Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalmodulin-dependent protein phosphatase activity

PPP3CA PPP3CB PPM1F

5.28e-0651633GO:0033192
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine phosphatase activity

PPP3CA PPP3CB PPM1F

2.90e-0581633GO:0004723
GeneOntologyMolecularFunctionglucose-6-phosphate dehydrogenase activity

H6PD G6PD

6.62e-0521632GO:0004345
GeneOntologyMolecularFunctionsteroid 11-beta-monooxygenase activity

CYP11B1 CYP11B2

6.62e-0521632GO:0004507
GeneOntologyMolecularFunctioncorticosterone 18-monooxygenase activity

CYP11B1 CYP11B2

6.62e-0521632GO:0047783
GeneOntologyBiologicalProcesslipid biosynthetic process

GPLD1 PGS1 ACACA GAL3ST1 CYP7A1 SPTLC2 CYP11B1 CYP11B2 SDR42E1 H6PD ABCA8 EFR3A PITPNM1 ABHD5 SH3GLB1 CHPT1 TM7SF2 SCO1 PAM ABCG2 PC GPAT2 G6PD GNPAT

2.07e-0881316124GO:0008610
GeneOntologyBiologicalProcessphospholipid biosynthetic process

PGS1 SPTLC2 ABCA8 EFR3A PITPNM1 ABHD5 SH3GLB1 CHPT1 PC GPAT2 GNPAT

8.66e-0626816111GO:0008654
GeneOntologyBiologicalProcesspeptide metabolic process

CPA4 ANPEP CHAC2 ECE1 PAM DNPEP

5.07e-05841616GO:0006518
GeneOntologyBiologicalProcesscortisol biosynthetic process

CYP11B1 CYP11B2 H6PD

5.38e-05101613GO:0034651
GeneOntologyBiologicalProcesstertiary alcohol biosynthetic process

CYP11B1 CYP11B2 H6PD

5.38e-05101613GO:1902645
GeneOntologyBiologicalProcessphospholipid metabolic process

GPLD1 PGS1 SPTLC2 ABCA8 EFR3A PITPNM1 ABHD5 SH3GLB1 CHPT1 PC GPAT2 GNPAT

9.41e-0541016112GO:0006644
GeneOntologyBiologicalProcesscortisol metabolic process

CYP11B1 CYP11B2 H6PD

9.75e-05121613GO:0034650
GeneOntologyCellularComponentglutamatergic synapse

GABRD CUL3 CACNA2D1 CTTNBP2 NRCAM TSPOAP1 L1CAM LAMA5 GRIA2 GRIN2D ERBIN EFR3A PPP3CA TENM4 PPP3CB LINGO1 LRRC7 PLXNA1

7.18e-0581716318GO:0098978
MousePhenoabnormal circulating mineral level

CUL3 EXOC6 PGS1 HSPA4L CYP7A1 CYP11B1 CYP11B2 BACH2 PAQR5 U2AF2 GRIN2D TFRC PITPNM1 PRDM8 RSAD2 PPP3CA TENM4 AP2A2 AGL ABCG2 LRBA HERC1

7.76e-0598212822MP:0006357
MousePhenoabnormal urine progesterone level

CYP11B1 CYP11B2

8.32e-0521282MP:0011545
MousePhenoabnormal urine deoxycorticosterone level

CYP11B1 CYP11B2

8.32e-0521282MP:0011552
MousePhenodecreased urine corticosterone level

CYP11B1 CYP11B2

8.32e-0521282MP:0011550
MousePhenoincreased urine deoxycorticosterone level

CYP11B1 CYP11B2

8.32e-0521282MP:0011553
MousePhenoincreased urine progesterone level

CYP11B1 CYP11B2

8.32e-0521282MP:0011546
MousePhenoabnormal axon morphology

NRCAM GAL3ST1 L1CAM THOC2 ERBIN RUFY3 SLC9A1 ARSA GNPAT

8.88e-051991289MP:0005404
MousePhenoabnormal mineral level

CUL3 EXOC6 PGS1 CTTNBP2 HSPA4L CYP7A1 CYP11B1 CYP11B2 BACH2 PAQR5 U2AF2 GRIN2D TFRC PITPNM1 PRDM8 RSAD2 PPP3CA TENM4 AP2A2 AGL ABCG2 LRBA HERC1

9.24e-05106612823MP:0000192
MousePhenoabnormal mineral homeostasis

CUL3 EXOC6 PGS1 CTTNBP2 HSPA4L CYP7A1 CYP11B1 CYP11B2 BACH2 PAQR5 U2AF2 GRIN2D TFRC PITPNM1 PRDM8 RSAD2 PPP3CA TENM4 AP2A2 AGL ABCG2 LRBA HERC1

1.06e-04107612823MP:0005636
MousePhenoincreased circulating mineral level

CUL3 EXOC6 PGS1 HSPA4L CYP11B1 CYP11B2 BACH2 PAQR5 PRDM8 RSAD2 TENM4 AP2A2 AGL ABCG2 LRBA HERC1

1.90e-0462612816MP:0014547
DomainG6PD_N

H6PD G6PD

7.29e-0521602PF00479
DomainG6P_DH_AS

H6PD G6PD

7.29e-0521602IPR019796
DomainCXorf40

EOLA1 EOLA2

7.29e-0521602IPR033615
DomainCyt_P450_mitochondrial

CYP11B1 CYP11B2

7.29e-0521602IPR002399
DomainG6P_DH

H6PD G6PD

7.29e-0521602IPR001282
DomainG6P_DEHYDROGENASE

H6PD G6PD

7.29e-0521602PS00069
DomainG6P_DH_C

H6PD G6PD

7.29e-0521602IPR022675
DomainG6P_DH_NAD-bd

H6PD G6PD

7.29e-0521602IPR022674
DomainG6PD_C

H6PD G6PD

7.29e-0521602PF02781
DomainASCH_domain

EOLA1 EOLA2

2.18e-0431602IPR007374
DomainASCH

EOLA1 EOLA2

2.18e-0431602SM01022
DomainGPAT/DHAPAT

GPAT2 GNPAT

2.18e-0431602IPR022284
DomainNeurofascin/L1/NrCAM_C

NRCAM L1CAM

4.33e-0441602IPR026966
DomainSEP_domain

UBXN11 UBXN2B

4.33e-0441602IPR012989
DomainSHR-BD

VPS13C VPS13B

4.33e-0441602IPR009543
DomainBravo_FIGEY

NRCAM L1CAM

4.33e-0441602PF13882
DomainVPS13_C

VPS13C VPS13B

4.33e-0441602PF16909
DomainSEP

UBXN11 UBXN2B

4.33e-0441602PF08059
DomainSEP

UBXN11 UBXN2B

4.33e-0441602PS51399
DomainVPS13_C

VPS13C VPS13B

4.33e-0441602IPR031645
DomainSHR-BD

VPS13C VPS13B

4.33e-0441602PF06650
DomainBiotin_BS

ACACA PC

7.17e-0451602IPR001882
DomainBiotin_COase_C

ACACA PC

7.17e-0451602IPR005482
DomainYD

NID2 TENM4

7.17e-0451602IPR006530
DomainAutophagy-rel_C

VPS13C VPS13B

7.17e-0451602IPR015412
DomainBC

ACACA PC

7.17e-0451602PS50979
DomainATG_C

VPS13C VPS13B

7.17e-0451602PF09333
DomainBiotin_carb_C

ACACA PC

7.17e-0451602SM00878
DomainBiotin_carb_C

ACACA PC

7.17e-0451602PF02785
DomainBiotin_carboxylation_dom

ACACA PC

7.17e-0451602IPR011764
DomainBIOTIN

ACACA PC

7.17e-0451602PS00188
DomainCupredoxin

TMED6 PKHD1L1 F8

8.43e-04221603IPR008972
DomainRudment_hybrid_motif

ACACA PC

1.07e-0361602IPR011054
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACA PC

1.49e-0371602IPR005479
DomainBC-like_N

ACACA PC

1.49e-0371602IPR005481
DomainCPSase_L_D2

ACACA PC

1.49e-0371602PF02786
DomainBiotin_carb_N

ACACA PC

1.49e-0371602PF00289
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

AHI1 CDC42BPA NRCAM VPS13C CHGB BBS9 PPP3CA SH3GLB1 CHPT1

1.15e-08128165930995482
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CUL3 CACNA2D1 CTTNBP2 NRCAM DOCK11 HECTD4 NSD1 GRIA2 GRIN2D ERBIN ITIH1 WDR91 PPP3CA PPP3CB AP2A2 LRRC7 PLCL1 MGA DNMT1

1.80e-079631651928671696
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CDC42BPA FAT3 NSD1 U2AF2 THOC2 CGNL1 LRBA HERC1 PC VPS13B

1.97e-072341651036243803
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GPC1 POMT2 CACNA2D1 ANPEP HSPA4L SPTLC2 L1CAM LAMA5 LAMC3 H6PD GALNT7 ECE1 UST TFRC ARSA CHPT1 PAM UGGT2 G6PD PLXNA1 DNMT1

2.87e-0712011652135696571
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPC1 CUL3 CACNA2D1 CTTNBP2 NRCAM HSPA4L PSMA7 L1CAM RBP3 GRIA2 PLEKHG5 ERBIN RUFY3 PITPNM1 PPP3CA TENM4 AP2A2 LRRC7 PLCL1 CGNL1 PC SYNCRIP DNPEP

3.27e-0714311652337142655
Pubmed

The extent of linkage disequilibrium caused by selection on G6PD in humans.

L1CAM F8 G6PD

4.18e-074165316020776
Pubmed

The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms.

CYP11B1 CYP11B2 PER2

1.04e-065165330321360
Pubmed

Na(+)/H(+) exchanger 1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophy.

SLC9A1 PPP3CA PPP3CB

1.04e-065165322688515
Pubmed

Sex Differences in Adrenal Bmal1 Deletion-Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice.

CYP11B1 CYP11B2 PER2

1.04e-065165331398249
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CUL3 NRCAM GRIA2 GRIN2D PITPNM1 PPP3CA PPP3CB AP2A2 LRRC7 PLCL1

1.05e-062811651028706196
Pubmed

Novel Cul3 binding proteins function to remodel E3 ligase complexes.

CUL3 ERBIN WDR91 CIITA LRRC7

1.30e-0640165525011449
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

NRCAM VPS13C CHGB BBS9 SH3GLB1 PPP3CB

3.34e-0685165623055939
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

CUL3 JCAD MYH7 ZNF326 TRPC4AP ACACA VPS13C LAMA5 ECE1 SV2C RIPOR1 HSF1 PPIH MGA G6PD

3.44e-067541651535906200
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

CUL3 CTTNBP2 GRIA2 GRIN2D ERBIN PPP3CA PPP3CB LRRC7 PLCL1

3.46e-06251165927507650
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CPA4 GPC1 CACNA2D1 POGLUT3 ACACA L1CAM LAMA5 LAMC3 GALNT7 ECE1 TFRC GLMN PPP3CA NAPRT MRPS23 UGGT2 G6PD DNMT1 SYNCRIP DNPEP

3.82e-0612971652033545068
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

GPLD1 CACNA2D1 NRCAM ANPEP L1CAM F8 TFRC FREM2 C1S

4.20e-06257165916335952
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

POMT2 PLIN4 NID2 POGLUT3 ACACA SPTLC2 LAMA5 H6PD GALNT7 CBL TFRC AARS2 PPM1F DHRS7 MRPS23 PAM UGGT2 G6PD PLXNA1 SYNCRIP DNPEP

5.71e-0614511652130550785
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CDC42BPA ACACA L1CAM HECTD4 NSD1 LAMA5 LAMC3 GRIN2D ECE1 PLEKHG5 PER2 NAPRT RIPOR1 LRBA HERC1 PC ANKRD33B PLXNA1

5.74e-0611051651835748872
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

NAGK HSPA4L PSMA7 L1CAM U2AF2 CHGB WDR91 PPP3CA PPP3CB AGL

5.87e-063411651029791485
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

POMT2 PGS1 AHI1 ANPEP LAMC3 THOC2 PLEKHG5 PITPNM1 PAOX WDR91 SLC9A1 AP2A2 NAPRT AASS AGL DNMT1

9.36e-069251651628986522
Pubmed

Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.

L1CAM F8 G6PD

1.23e-051016531964443
Pubmed

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.

CUL3 ZBTB16 DNMT1 SYNCRIP

1.39e-0531165423086144
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

POMT2 POGLUT3 LAMA5 H6PD ECE1 TFRC TENM4

1.42e-05164165732409323
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

GPC1 CUL3 NAGK ACACA HSPA4L PSMA7 PPP3CA SH3GLB1 PPP3CB TELO2 NAPRT AGL RIPOR1 LRBA HERC1 HSF1 G6PD KYNU SYNCRIP DNPEP

2.03e-0514551652022863883
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ZNF326 CDC42BPA ACACA VPS13C U2AF2 PKHD1L1 ERBIN RUFY3 PPP3CA CGNL1 LRBA PC MGA DNMT1

2.22e-057771651435844135
Pubmed

Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.

CYP11B1 CYP11B2

2.24e-052165223150505
Pubmed

GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

2.24e-052165235012455
Pubmed

Role of genetic variation in regulation of aldosterone biosynthesis.

CYP11B1 CYP11B2

2.24e-052165221164264
Pubmed

Gender-based differences on the association between salt-sensitive genes and obesity in Korean children aged between 8 and 9 years.

CYP11B2 GRK4

2.24e-052165225768006
Pubmed

The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.

CYP11B1 CYP11B2

2.24e-05216528645611
Pubmed

Role of Apg-1 in HSF1 activation and bortezomib sensitivity in myeloma cells.

HSPA4L HSF1

2.24e-052165231899217
Pubmed

High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis.

H6PD G6PD

2.24e-052165220032314
Pubmed

Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.

CYP11B1 CYP11B2

2.24e-052165212231255
Pubmed

A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.

CYP11B1 CYP11B2

2.24e-052165220634641
Pubmed

Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.

CYP11B1 CYP11B2

2.24e-05216521303253
Pubmed

Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity.

PPP3CA PPP3CB

2.24e-052165219861587
Pubmed

Inhibition of calcineurin phosphatase promotes exocytosis of renin from juxtaglomerular cells.

PPP3CA PPP3CB

2.24e-052165219907416
Pubmed

Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.

CYP11B1 CYP11B2

2.24e-05216521741400
Pubmed

Chromosomal assignments of the genes for the calcineurin A alpha (Calna1) and A beta subunits (Calna2) in the rat.

PPP3CA PPP3CB

2.24e-05216528187553
Pubmed

Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.

CYP11B1 CYP11B2

2.24e-052165232540969
Pubmed

Dephosphorylation of the small heat shock protein hsp25 by calcium/calmodulin-dependent (type 2B) protein phosphatase.

PPP3CA PPP3CB

2.24e-05216521328240
Pubmed

Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.

CYP11B1 CYP11B2

2.24e-052165226047574
Pubmed

Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.

CYP11B1 CYP11B2

2.24e-052165226324851
Pubmed

Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.

CYP11B1 CYP11B2

2.24e-05216527669222
Pubmed

Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.

CYP11B1 CYP11B2

2.24e-052165222933298
Pubmed

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.

CYP11B1 CYP11B2

2.24e-05216522783417
Pubmed

Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.

CYP11B1 CYP11B2

2.24e-05216522256920
Pubmed

Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.

CYP11B1 CYP11B2

2.24e-052165220708777
Pubmed

Molecular genetic studies on the biosynthesis of aldosterone in humans.

CYP11B1 CYP11B2

2.24e-052165222217843
Pubmed

Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.

CYP11B1 CYP11B2

2.24e-052165216396990
Pubmed

Genetic conservation of the immunophilin-binding domains of human calcineurin A1 and A2.

PPP3CA PPP3CB

2.24e-052165211005320
Pubmed

[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.

CYP11B1 CYP11B2

2.24e-052165218397978
Pubmed

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.

CYP11B1 CYP11B2

2.24e-05216521518866
Pubmed

Procollagen I-expressing renin cell precursors.

CYP11B1 CYP11B2

2.24e-052165223761669
Pubmed

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).

CYP11B1 CYP11B2

2.24e-05216522592361
Pubmed

Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain.

PPP3CA PPP3CB

2.24e-05216522556704
Pubmed

Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.

CYP11B1 CYP11B2

2.24e-052165223314847
Pubmed

Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.

CYP11B1 CYP11B2

2.24e-052165217980006
Pubmed

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

CYP11B1 CYP11B2

2.24e-052165216984984
Pubmed

Evidence for local aldosterone synthesis in the large intestine of the mouse.

CYP11B1 CYP11B2

2.24e-052165235288482
Pubmed

Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.

CYP11B1 CYP11B2

2.24e-052165215731365
Pubmed

Nucleotide variability at G6pd and the signature of malarial selection in humans.

L1CAM G6PD

2.24e-052165212524354
Pubmed

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

CYP11B1 CYP11B2

2.24e-052165217651452
Pubmed

Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.

CYP11B1 CYP11B2

2.24e-052165234743356
Pubmed

Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.

CYP11B1 CYP11B2

2.24e-052165220339375
Pubmed

Coexpression of calcineurin A and B subunits in various subcellular and synaptic compartments of cerebellar neurons and glia with particular abundance at parallel fiber-Purkinje cell synapses.

PPP3CA PPP3CB

2.24e-052165235247520
Pubmed

Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development.

NRCAM L1CAM

2.24e-052165211564762
Pubmed

Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

2.24e-052165220808686
Pubmed

The role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses.

PPP3CA PPP3CB

2.24e-052165220810903
Pubmed

Loss of rapid transferrin receptor recycling due to a mutation in Sec15l1 in hbd mice.

EXOC6 TFRC

2.24e-052165217087999
Pubmed

Calcineurin A-alpha but not A-beta is required for normal kidney development and function.

PPP3CA PPP3CB

2.24e-052165215509543
Pubmed

Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.

CYP11B1 CYP11B2

2.24e-052165221519965
Pubmed

Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.

CYP11B1 CYP11B2

2.24e-052165221625068
Pubmed

Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.

CYP11B1 CYP11B2

2.24e-052165216110193
Pubmed

Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.

CYP11B1 CYP11B2

2.24e-052165226066897
Pubmed

Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans.

ZBTB16 CIITA

2.24e-052165220038602
Pubmed

Autosomal control of an electrophoretic variant of glucose-6-phosphate dehydrogenase in the mouse (Mus musculus).

H6PD G6PD

2.24e-05216525693479
Pubmed

Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.

CYP11B1 CYP11B2

2.24e-052165218651133
Pubmed

Calcineurin mediates the angiotensin II-induced aldosterone synthesis in the adrenal glands by up-regulation of transcription of the CYP11B2 gene.

CYP11B2 PPP3CA

2.24e-052165220413672
Pubmed

A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.

CYP11B1 CYP11B2

2.24e-052165222083159
Pubmed

Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.

CYP11B1 CYP11B2

2.24e-052165215699546
Pubmed

Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.

CYP11B1 CYP11B2

2.24e-052165218162527
Pubmed

Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.

CYP11B1 CYP11B2

2.24e-052165238341019
Pubmed

Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation.

PER2 HSF1

2.24e-052165236871756
Pubmed

Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.

CYP11B1 CYP11B2

2.24e-052165224837548
Pubmed

Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.

CYP11B1 CYP11B2

2.24e-052165230046010
Pubmed

Familial and phenotypic associations of the aldosterone Renin ratio.

CYP11B1 CYP11B2

2.24e-052165219820005
Pubmed

Calcineurin expression and activity is regulated by the intracellular redox status and under hypertension in human neutrophils.

PPP3CA PPP3CB

2.24e-052165222739212
Pubmed

Cloning and expression of human arylsulfatase A.

GAL3ST1 ARSA

2.24e-05216522562955
Pubmed

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

CYP11B1 CYP11B2

2.24e-052165222622494
Pubmed

Are calcineurin genes associated with athletic status? A function, replication study.

PPP3CA PPP3CB

2.24e-052165221233773
Pubmed

Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.

CYP11B1 CYP11B2

2.24e-052165215062555
Pubmed

Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.

CYP11B1 CYP11B2

2.24e-052165217075030
Pubmed

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.

CYP11B1 CYP11B2

2.24e-052165217075029
Pubmed

The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome.

CPA4 CPA5

2.24e-052165212676894
Pubmed

CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.

CYP11B1 CYP11B2

2.24e-052165215507509
Pubmed

Polymorphism of CYP11B2 determines salt sensitivity in Japanese.

CYP11B1 CYP11B2

2.24e-052165217296872
Pubmed

Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.

CYP11B1 CYP11B2

2.24e-052165218039983
Pubmed

Oxidation-induced conformational changes in calcineurin determined by covalent labeling and tandem mass spectrometry.

PPP3CA PPP3CB

2.24e-052165225286016
Pubmed

Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.

CYP11B1 CYP11B2

2.24e-052165219029289
InteractionSUSD4 interactions

NID2 CACNA2D1 POGLUT3 LAMA5 ECE1 ARSA PAM PLXNA1

4.85e-09501588int:SUSD4
InteractionCEACAM8 interactions

CACNA2D1 GLB1L LAMA5 GALNT7 ECE1 FREM2 PAM UGGT2

4.49e-061191588int:CEACAM8
InteractionTMEM25 interactions

NID2 POGLUT3 ACACA LAMA5 ARSA PAM PC PLXNA1

1.08e-051341588int:TMEM25
InteractionPRG2 interactions

CPA4 GPC1 POGLUT3 TRPC4AP LAMA5 LAMC3 H6PD ECE1 PAM UGGT2 PLXNA1

1.60e-0528515811int:PRG2
InteractionC1QTNF7 interactions

POMT2 POGLUT3 LAMA5 H6PD LINGO1 PAM

1.68e-05691586int:C1QTNF7
InteractionTAFAZZIN interactions

NID2 CACNA2D1 CPA5 CHGB H6PD GALNT7 FREM2 PAM PLXNA1

3.83e-052071589int:TAFAZZIN
InteractionODAPH interactions

GPC1 TRPC4AP ACACA FAT3 LAMA5

4.01e-05491585int:ODAPH
InteractionPDGFRA interactions

POGLUT3 GLB1L LAMA5 H6PD GALNT7 ECE1 CBL ERBIN TFRC PAM UGGT2 PLXNA1

5.36e-0538515812int:PDGFRA
InteractionPTCH1 interactions

POMT2 CUL3 CACNA2D1 PSMA7 L1CAM LAMA5 GALNT7 ECE1 PAM PLXNA1

6.07e-0527315810int:PTCH1
InteractionLGALS1 interactions

NID2 TRPC4AP NRCAM FAT3 L1CAM LAMA5 U2AF2 ECE1 FREM2 PLXNA1 HSPB2

6.43e-0533215811int:LGALS1
Cytoband2q36.2

CUL3 FAM124B

3.84e-05316522q36.2
Cytoband17q22-q23

TSPOAP1 MRPS23

1.91e-046165217q22-q23
CytobandXq28

L1CAM EOLA1 F8 EOLA2 G6PD

4.57e-041761655Xq28
GeneFamilyCytochrome P450 family 11

CYP11B1 CYP11B2

1.12e-04311121007
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

AHI1 CDC42BPA VPS13C ERBIN RUFY3 TENM4 UGGT2 LRBA VPS13B

1.13e-061691629M39230
CoexpressionGSE27786_BCELL_VS_CD8_TCELL_UP

EXOC6 ZNF326 L1CAM TFRC SH3GLB1 CIITA PPIH ANKRD33B RASGRP2

4.53e-062001629M4801
CoexpressionBONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING

ZBTB16 VPS13C U2AF2 ECE1 F8 ABCA8 PAOX PPP3CA PPP3CB TELO2 PAM ABCG2 HERC1

1.69e-0550616213M253
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

INTS6L CACNA2D1 AHI1 SFRP2 TMED6 ACACA NRCAM TSPOAP1 GAL3ST1 CDHR1 NSD1 PAQR5 GALNT7 TFRC RSAD2 CHPT1 PAM MGA VPS13B SYNCRIP

1.61e-0679515620gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

ZBTB16 BACH2 ECE1 UST ABCA8 PPP3CA KCNT2 C1S UGGT2

5.01e-0819516596a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NID2 ZNF326 L1CAM PRDM8 PLCL1 PC ANKRD33B PLXNA1

1.94e-0716516589d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACACA PAQR5 PGM5 LINGO1 AP2A2 TM7SF2 MGA PLXNA1

3.47e-071781658c87945146b2734141f07b39d268e0d8086ee0364
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLIN4 CACNA2D1 SFRP2 LAMC3 KCNT2 C1S EPHX3 HSPB2

4.28e-0718316588de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

EXOC6 JCAD ZBTB16 NRCAM LAMA5 FREM2 ABCG2 CGNL1

5.04e-0718716587e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANPEP DOCK11 CBL TFRC ABHD5 CIITA MYO1F KYNU

7.76e-071981658e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANPEP DOCK11 CBL TFRC ABHD5 CIITA MYO1F KYNU

7.76e-0719816580baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

JCAD NID2 LAMC3 ECE1 TFRC ABCG2 CGNL1 FAM124B

8.06e-071991658b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

JCAD NID2 LAMC3 ECE1 TFRC ABCG2 CGNL1 FAM124B

8.06e-0719916580b4edf3e359749827ef978a77b5267ddde732d71
ToppCellBiopsy_Control_(H.)-Mesenchymal-Mesothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CPA4 NID2 CACNA2D1 PKHD1L1 ABCA8 KCNT2 C1S HSPB2

8.06e-071991658ca970114b5aef4518ce580897a62ac88688b2671
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

JCAD NID2 LAMC3 ECE1 TFRC ABCG2 CGNL1 FAM124B

8.06e-0719916589e01eee126247a0696c71b019f855a8a41a0ede3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

CTTNBP2 BACH2 L1CAM GRIA2 CHGB PPP3CA LINGO1 LRRC7

8.37e-072001658c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

CTTNBP2 NRCAM L1CAM GRIA2 RUFY3 PRDM8 PPP3CA LRRC7

8.37e-07200165809fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRD ITGAD UST PITPNM1 TENM4 MYO1F PLXNA1

2.02e-061571657ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 ZBTB16 NRCAM BACH2 ECE1 KCNT2 AASS

2.92e-06166165794636dbc039f794c735960c3425e00bdd5523602
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPLD1 GLB1L LAMC3 H6PD F8 GLMN C1S

3.16e-061681657d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

JCAD ZBTB16 ABCA8 PGM5 PRDM8 ABCG2 PLCL1

3.16e-061681657a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NSD1 PAQR5 ZNF510 UST MLH3 TELO2 FAM124B

3.29e-0616916570425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NSD1 PAQR5 ZNF510 UST MLH3 TELO2 FAM124B

3.29e-061691657fec669968a77060bd77ee8695034e35a642c984f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 VPS13C ITGAD F8 HERC1 PC ANKRD33B

3.98e-061741657f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 VPS13C NSD1 ERBIN KCNT2 CHPT1 PAM

4.30e-061761657749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

PLIN4 GPLD1 ACACA DOCK11 LGALS12 TENM4 PC

5.55e-061831657b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

PLIN4 GPLD1 ACACA DOCK11 LGALS12 TENM4 PC

5.55e-0618316573f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ANPEP H6PD ITIH1 AGL C1S PC

5.55e-061831657d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA2D1 MYH7 FAT3 GRIA2 PPP3CA LINGO1 ANKRD33B

6.86e-0618916574b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ECE1 PKHD1L1 PGM5 RSAD2 PPM1F RIPOR1 ABCG2

7.34e-06191165779b399496bd7322a1d53c43378f48695fd09a5d9
ToppCellfacs-Trachea-24m-Endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ECE1 PKHD1L1 PGM5 RSAD2 PPM1F RIPOR1 ABCG2

7.34e-0619116579c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ECE1 PKHD1L1 PGM5 RSAD2 PPM1F RIPOR1 ABCG2

7.34e-0619116571b1e943709d0c3283a980c7c965ef1f110506a29
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

ANPEP DOCK11 TFRC ABHD5 CIITA MYO1F KYNU

7.34e-061911657dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANPEP DOCK11 TFRC ABHD5 CIITA MYO1F KYNU

7.60e-061921657bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA2D1 ZBTB16 NRCAM FAT3 UST CHPT1 LRBA

7.60e-0619216576c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

BACH2 ECE1 UST ABCA8 KCNT2 C1S UGGT2

7.60e-061921657356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 AHI1 TSPOAP1 L1CAM GRIA2 TENM4 LINGO1

7.86e-061931657be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LINC00518 CTTNBP2 NRCAM ABCA8 LINGO1 C1S HSPB2

7.86e-0619316576be11fef87af04ee7a3cc223882ccd4077caded9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 AHI1 TSPOAP1 L1CAM GRIA2 TENM4 LINGO1

7.86e-0619316570c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 AHI1 TSPOAP1 L1CAM GRIA2 TENM4 LINGO1

7.86e-0619316578689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 BACH2 ECE1 ABCA8 AASS C1S DNMT1

7.86e-061931657261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CPA4 CACNA2D1 NRCAM LAMA5 CHPT1 PAM C1S

8.13e-061941657f44394c8a6f86483063f2f5722f003a8a0a70254
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

ANPEP DOCK11 SPTLC2 TFRC AP2A2 MYO1F KYNU

8.13e-061941657ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAGK SPTLC2 RUFY3 RSAD2 CIITA NAPRT KYNU

8.41e-061951657dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAGK SPTLC2 RUFY3 RSAD2 CIITA NAPRT KYNU

8.41e-061951657d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPC1 NRCAM LAMA5 FREM2 PAM C1S PLXNA1

8.69e-061961657b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

BACH2 ECE1 UST ABCA8 PPP3CA KCNT2 UGGT2

8.69e-061961657e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CACNA2D1 L1CAM GRIA2 CHGB RUFY3 DUOX1 LINGO1

8.98e-061971657c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-PNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

CACNA2D1 L1CAM GRIA2 CHGB PRDM8 LINGO1 LRRC7

8.98e-06197165710e72b425a2bcba35e63a5b074d3dedcd49a762e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRD JCAD NID2 ECE1 EVA1B PPM1F ABCG2

8.98e-0619716579244f087ba4b60fdc81d54ce91860de715b3e12c
ToppCellImmune|World / Lineage, Cell type, age group and donor

ANPEP DOCK11 CBL TFRC CIITA MYO1F KYNU

9.28e-06198165765681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal|3_mon / Sample Type, Dataset, Time_group, and Cell type.

CTTNBP2 BACH2 GRIA2 CHGB PPP3CA LINGO1 LRRC7

9.28e-061981657a0032e3ed259e39324a659490b9d340c5d9ba0fc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD NID2 SFRP2 LAMC3 ABCA8 C1S HSPB2

9.59e-061991657dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

JCAD NID2 SFRP2 LAMC3 ABCA8 C1S HSPB2

9.59e-06199165712133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

BACH2 GRIA2 CHGB RUFY3 PPP3CA LINGO1 LRRC7

9.59e-0619916570cd3e4e0fba000c996feaf012ff32198e1048c9d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD NID2 SFRP2 LAMC3 ABCA8 C1S HSPB2

9.59e-061991657c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

CTTNBP2 NRCAM L1CAM GRIA2 RUFY3 PRDM8 PPP3CA

9.91e-062001657e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

CTTNBP2 BACH2 GRIA2 CHGB PPP3CA LINGO1 LRRC7

9.91e-062001657af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 NRCAM BACH2 ECE1 KCNT2 AASS

2.21e-051521656621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ANPEP ITIH1 TM7SF2 C1S PC

2.56e-051561656e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 FAT3 PKHD1L1 KCNT2 AASS C1S

2.95e-051601656c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 FAT3 PKHD1L1 KCNT2 AASS C1S

2.95e-05160165625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRD ITGAD UST TENM4 PLCL1 PLXNA1

3.28e-0516316568dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRD ITGAD UST TENM4 PLCL1 PLXNA1

3.28e-051631656fd243ca223079033be480a24817a399f281fa4d4
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAC2 RSAD2 SH3GLB1 ABCG2 HERC1 PC

3.39e-051641656f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

PLIN4 DOCK11 LGALS12 ABHD5 TENM4 PC

3.63e-0516616567e5852891714465c6228c9f955fd511ec79d0e02
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLIN4 HECTD4 LAMA5 FREM2 TM7SF2 CGNL1

3.63e-05166165689e2b8453180983533faccb4275867861876d7ee
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR5 PKHD1L1 F8 PGM5 CGNL1 ANKRD33B

3.75e-051671656a4a795751644b22af616335379e64ae95175180c
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAC2 HECTD4 TFRC RSAD2 ABCG2 PC

3.88e-05168165608fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAC2 HECTD4 TFRC RSAD2 ABCG2 PC

3.88e-051681656d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ACACA H6PD ITIH1 C1S PC

3.88e-051681656b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF326 C12orf56 VPS13C MCMDC2 FREM2 CHPT1

3.88e-051681656d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ACACA H6PD ITIH1 C1S PC

3.88e-051681656073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ACACA H6PD ITIH1 C1S PC

4.01e-051691656f195467438c589f87224bde7da720dea072d110c
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ECE1 PGM5 KCNT2 PAN2 ABCG2 GPAT2

4.01e-05169165658136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ACACA H6PD ITIH1 C1S PC

4.01e-0516916567785cab967a33560830c394c918d6ce625103858
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LGALS12 CHPT1 AASS ABCG2 PC

4.01e-051691656ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ECE1 PGM5 KCNT2 PAN2 ABCG2 GPAT2

4.01e-05169165604c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LGALS12 CHPT1 AASS ABCG2 PC

4.01e-051691656922086f218135b734b7d370b871923e50141edce
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

JCAD ZBTB16 ABCA8 PGM5 PRDM8 PLCL1

4.15e-051701656cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

JCAD ZBTB16 ABCA8 PGM5 PRDM8 PLCL1

4.15e-0517016560bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

JCAD ZBTB16 ABCA8 PGM5 PRDM8 PLCL1

4.15e-051701656516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

PLIN4 DOCK11 LGALS12 ABHD5 TENM4 PC

4.57e-051731656c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIN2D ITGAD ITIH1 CIITA ANKRD33B KYNU

4.72e-05174165616204ff504b7b382b4d90ca35003ad5336020e07
ToppCellfacs-Heart-RV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGS1 TSPOAP1 L1CAM PAQR5 DUOX1 PLXNA1

4.87e-051751656bde002379088c0407afd0f3dae60b6a166683957
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NID2 CACNA2D1 NRCAM L1CAM LAMC3 HSPB2

4.87e-051751656f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 GRIA2 PKHD1L1 F8 PGM5 LINGO1

5.19e-0517716566e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 GRIA2 PKHD1L1 F8 PGM5 LINGO1

5.19e-051771656e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCelldroplet-Marrow-nan-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAC2 HECTD4 RSAD2 SH3GLB1 ABCG2 PC

5.36e-051781656b4e15c176875cd226854a0019495309d02730c42
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLIN4 TM7SF2 GPAT2 EPHX3 HSPB2 RASGRP2

5.52e-051791656d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLIN4 TM7SF2 GPAT2 EPHX3 HSPB2 RASGRP2

5.52e-0517916566be47c877250968a916c711ba0787eb7b4c5443d
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAC2 HECTD4 RSAD2 SH3GLB1 ABCG2 PC

5.52e-0517916567e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 UST DUOX1 RSAD2 AP2A2 PLXNA1

5.70e-0518016566c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD CHGB F8 PGM5 WDR89 PAM

5.70e-051801656dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD CHGB F8 PGM5 WDR89 PAM

5.70e-051801656423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 NRCAM BACH2 ECE1 KCNT2 AASS

5.70e-05180165601f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMED6 CPA5 CHGB ECE1 ITIH1 LINGO1

5.70e-0518016560677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FAT3 LAMC3 ABCA8 KCNT2 C1S

5.88e-051811656c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 CTTNBP2 DOCK11 FAT3 KCNT2 ANKRD33B

5.88e-0518116566956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FAT3 LAMC3 ABCA8 KCNT2 C1S

5.88e-051811656c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellNS-critical-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LINC00518 NRCAM L1CAM ABCA8 LINGO1 HSPB2

6.06e-051821656dd1c59babf7211362452e3e264009d70004d99f6
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR1 CHGB ECE1 PKHD1L1 PGM5 CGNL1

6.24e-0518316566c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRCAM CYP7A1 FAT3 PKHD1L1 FREM2 TENM4

6.44e-0518416562cbed6462fea2622871bb7e49b0df3d984239281
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

GPC1 CACNA2D1 NRCAM CDHR1 BACH2 TENM4

6.44e-051841656ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
Drughydroxyl radicals

CPA4 GPLD1 CPA5 ANPEP GAL3ST1 CYP7A1 CYP11B1 CYP11B2 GLB1L RBP3 H6PD F8 FMO6P PAOX ARSA PPP3CA PPP3CB AP2A2 NAPRT AASS PPM1F AGL TM7SF2 PAM PLCL1 PC G6PD EPHX3 KYNU

6.48e-08134116129CID000000961
DrugNADP(H

ACACA ANPEP CYP7A1 SPTLC2 CYP11B1 CYP11B2 GLB1L H6PD FMO6P DUOX1 PER2 AASS TM7SF2 PC G6PD KYNU GNPAT

2.17e-0752716117CID000000930
Drugbeta-NADP

ACACA CYP7A1 SPTLC2 CYP11B1 CYP11B2 GLB1L H6PD F8 FMO6P DUOX1 AASS TM7SF2 PC G6PD KYNU GNPAT

4.28e-0749016116CID000000929
Drugepoxiconazole

GPC1 NAGK NRCAM CYP11B1 CYP11B2 GRIA2 THOC2 ITIH1 RSAD2 NAPRT AASS LRRC7 PC

9.91e-0734116113ctd:C109476
DrugH526

CPA4 CACNA2D1 CPA5 ANPEP CYP11B1 ECE1 PAOX DUOX1 PAM DNPEP

1.16e-0619216110CID000002550
DrugLaevuflex

MYH7 ACACA ANPEP HSPA4L L1CAM H6PD SLC9A1 AGL HERC1 PC G6PD

3.96e-0627216111CID000003426
DrugAC1L9ITU

NAGK ACACA TFRC CIITA CGNL1 PC G6PD

5.09e-06951617CID000445947
Drugcyproconazole

ZBTB16 NAGK NRCAM CYP11B1 CYP11B2 THOC2 ITIH1 RSAD2 NAPRT AASS TM7SF2 PC

5.12e-0633616112ctd:C093628
DrugAC1Q6PCP

CACNA2D1 MYH7 CYP7A1 CYP11B1 CYP11B2 PAQR5 DUOX1 SLC9A1 ABCG2 G6PD

5.84e-0623016110CID000005267
DrugHomosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

SPTLC2 GRK4 NSD1 ZNF510 ECE1 SLC9A1 MLH3 C1S DNPEP

1.07e-0519516194533_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A

NSD1 ECE1 CBL MLH3 TENM4 TELO2 AASS HSF1 VPS13B

1.16e-0519716196727_DN
DrugMoxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A

GPC1 AHI1 H6PD CBL F8 PITPNM1 SLC9A1 RIPOR1 VPS13B

1.16e-0519716197343_UP
DrugNitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A

POMT2 CACNA2D1 CDC42BPA CDHR1 H6PD CBL RUFY3 VPS13B RASGRP2

1.26e-0519916192303_UP
DrugAC1L19XE

CTTNBP2 GAL3ST1 CYP7A1 H6PD SH3GLB1 G6PD

2.74e-05831616CID000000744
Drugglucuronic acid 2-sulfate

L1CAM F8 ARSA G6PD

3.19e-05261614CID000126960
Drugangiotensin

CPA4 CPA5 ANPEP CYP11B1 CYP11B2 ECE1 DUOX1 SLC9A1 TM7SF2 DNPEP

3.40e-0528216110CID003083715
Drugcyadox

CYP11B1 CYP11B2

4.97e-0521612ctd:C020728
Drug18-hydroxydeoxycorticosterone

CYP11B1 CYP11B2

4.97e-0521612ctd:C042509
DrugBay a 4798

CYP7A1 G6PD

4.97e-0521612CID000182522
Drugoxygen

CACNA2D1 CYP7A1 CYP11B1 CYP11B2 FMO6P TFRC PAOX DUOX1 TM7SF2 SCO1 PAM G6PD KYNU

5.77e-0549916113CID000000977
DrugAcacetin [480-44-4]; Down 200; 14uM; HL60; HT_HG-U133A

BBS9 PAOX EVA1B PPP3CB AGL PRRG4 RASGRP2 SYNCRIP

6.42e-0519016182189_DN
Drugpicolinic acid

ACACA TFRC NAPRT G6PD KYNU

6.63e-05601615CID000001018
Drugretinoic acid; Down 200; 1uM; PC3; HT_HG-U133A

POMT2 L1CAM BBS9 WDR91 TM7SF2 RIPOR1 PC PLXNA1

7.43e-0519416181211_DN
DrugAG-012559 [369370-06-9]; Up 200; 10uM; MCF7; HT_HG-U133A

CACNA2D1 L1CAM H6PD UST RUFY3 EVA1B PPM1F STOML1

7.98e-0519616186889_UP
DrugMethoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; PC3; HT_HG-U133A

GPC1 CDC42BPA H6PD ECE1 SLC9A1 AP2A2 STOML1 MYO1F

7.98e-0519616186627_DN
DrugNicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A

POMT2 ECE1 PITPNM1 WDR91 MLH3 TELO2 G6PD PLXNA1

7.98e-0519616182058_DN
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A

AHI1 GRK4 ECE1 BBS9 MLH3 AP2A2 C1S HSF1

8.27e-0519716184544_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; HL60; HG-U133A

CUL3 SPTLC2 CHGB CBL PAOX PC PLXNA1 RASGRP2

8.27e-0519716182024_UP
DrugDihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; PC3; HT_HG-U133A

POMT2 NRCAM GRK4 LAMC3 ECE1 DUOX1 AP2A2 MYO1F

8.27e-0519716185751_UP
DrugPrimidone [125-33-7]; Up 200; 18.4uM; HL60; HT_HG-U133A

GPC1 GPLD1 SPTLC2 ECE1 DUOX1 KYNU RASGRP2 DNPEP

8.27e-0519716183065_UP
DrugAcebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A

CDC42BPA LAMA5 U2AF2 BBS9 PITPNM1 EVA1B AP2A2 PPM1F

8.57e-0519816181493_UP
DrugPridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A

POMT2 CACNA2D1 CDC42BPA VPS13C H6PD AP2A2 ABCG2 DNPEP

8.57e-0519816182715_UP
DrugPHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A

POMT2 CDC42BPA CBL PAOX WDR91 SLC9A1 RIPOR1 SECTM1

8.57e-0519816183854_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A

POMT2 PGS1 TRPC4AP AHI1 SPTLC2 PITPNM1 TM7SF2 UGGT2

8.57e-0519816182047_DN
Drugcorticosterone

TSPOAP1 GAL3ST1 CYP7A1 CYP11B1 CYP11B2 GRIN2D H6PD PER2 ABCG2 G6PD DNMT1

8.85e-0538116111CID000005753
Drughaloperidol; Down 200; 10uM; PC3; HT_HG-U133A

NID2 CDC42BPA SPTLC2 SLC9A1 TENM4 AP2A2 TELO2 PC

8.87e-0519916181203_DN
Diseasecell growth regulator with EF hand domain protein 1 measurement

NID2 CYP11B1 CYP11B2

2.36e-05111573EFO_0801461
DiseaseGlucocorticoid-remediable aldosteronism

CYP11B1 CYP11B2

2.81e-0521572C1260386
Diseaseadrenal cortical adenoma (is_marker_for)

CYP11B1 CYP11B2

2.81e-0521572DOID:0050891 (is_marker_for)
Diseasebile acid measurement

CYP7A1 UBXN2B

2.81e-0521572EFO_0020050
DiseaseMalignant neoplasm of breast

GPC1 NID2 SFRP2 NRCAM GRIN2D H6PD TFRC LLGL1 KCNT2 PER2 PPM1F MRPS23 LRRC7 ABCG2 LRBA VPS13B DNMT1

6.23e-05107415717C0006142
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13B

8.41e-0531572DOID:0111590 (implicated_via_orthology)
Diseasecongenital adrenal hyperplasia (implicated_via_orthology)

CYP11B1 CYP11B2

8.41e-0531572DOID:0050811 (implicated_via_orthology)
Diseaseschizophrenia (is_marker_for)

GRIN2D PPP3CA PPP3CB DNMT1

8.87e-05441574DOID:5419 (is_marker_for)
Diseasecholelithiasis

CYP7A1 NSD1 UBXN2B LRBA VPS13B

1.10e-04881575EFO_0004799
DiseaseCholecystitis

CYP7A1 UBXN2B LRBA

1.35e-04191573HP_0001082
Diseasephotoreceptor cell layer thickness measurement

CDC42BPA ATOH7 CDHR1 RBP3 DUOX1 PLCL1

1.46e-041481576EFO_0803370
Diseaseprolyl 4-hydroxylase subunit alpha-2 measurement

GPLD1 C1S

1.68e-0441572EFO_0802918
Diseasecongestive heart failure (biomarker_via_orthology)

MYH7 CYP11B1 ECE1 HSF1 DNMT1

2.75e-041071575DOID:6000 (biomarker_via_orthology)
Disease7-alpha-hydroxy-3-oxo-4-cholestenoate 7-Hoca measurement

CYP7A1 UBXN2B

2.78e-0451572EFO_0021116
Diseaseprimary hyperaldosteronism (is_implicated_in)

CYP11B1 CYP11B2

2.78e-0451572DOID:446 (is_implicated_in)
Diseasefibroblast growth factor 19 measurement

CYP7A1 UBXN2B

2.78e-0451572EFO_0010782
DiseaseConn Syndrome

CYP11B1 CYP11B2

4.16e-0461572C1384514
Diseasesegment polarity protein dishevelled homolog DVL-2 measurement

ITIH1 C1S

4.16e-0461572EFO_0802044
Diseasetaurocholenate sulfate measurement

CYP7A1 UBXN2B

4.16e-0461572EFO_0800277
DiseaseHyperaldosteronism

CYP11B1 CYP11B2

4.16e-0461572C0020428
Diseasecardiomyopathy (implicated_via_orthology)

MYH7 PPP3CA PPP3CB SCO1

5.68e-04711574DOID:0050700 (implicated_via_orthology)
Diseaseprotocadherin alpha-7 measurement

CYP11B1 CYP11B2

5.80e-0471572EFO_0801973
Diseasetaurochenodeoxycholic acid 3-sulfate measurement

CYP7A1 UBXN2B

5.80e-0471572EFO_0800584
DiseaseMASA syndrome (implicated_via_orthology)

NRCAM L1CAM

5.80e-0471572DOID:0060246 (implicated_via_orthology)
Diseasebitter non-alcoholic beverage consumption measurement

CUL3 PPP3CA FAM124B

6.54e-04321573EFO_0010093
Diseasebrain infarction (biomarker_via_orthology)

CACNA2D1 CYP11B1 CYP11B2

7.17e-04331573DOID:3454 (biomarker_via_orthology)
Diseasefocal segmental glomerulosclerosis (is_marker_for)

PPP3CA PPP3CB

7.71e-0481572DOID:1312 (is_marker_for)
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C AARS2

7.71e-0481572DOID:0050753 (implicated_via_orthology)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 1

SPTLC2 DNMT1

7.71e-0481572C0020071
Diseasehypothyroidism (biomarker_via_orthology)

MYH7 L1CAM SLC9A1 PAM

8.91e-04801574DOID:1459 (biomarker_via_orthology)
Diseasealcohol drinking

FAT3 HECTD4 LINGO1 PLCL1

9.34e-04811574EFO_0004329
Diseaseprotein FAM163B measurement

CYP11B1 CYP11B2

9.88e-0491572EFO_0802936
Diseasecataract (implicated_via_orthology)

SLC9A1 G6PD VPS13B

1.09e-03381573DOID:83 (implicated_via_orthology)
Diseasefeeling nervous measurement

CACNA2D1 TRPC4AP ITIH1 MGA

1.22e-03871574EFO_0009597
Diseaseadseverin measurement

CYP11B1 C1S

1.23e-03101572EFO_0801358
Diseaselevel of Ceramide (d42:1) in blood serum

CYP7A1 UBXN2B

1.23e-03101572OBA_2045187
Diseaseandrostenedione measurement

CYP11B1 CYP11B2

1.23e-03101572EFO_0007972
Diseaselipid measurement, lipoprotein measurement

TMED6 CYP7A1 LLGL1 UBXN2B

1.38e-03901574EFO_0004529, EFO_0004732
Diseasefibrinogen measurement, coronary artery disease

JCAD SFRP2 HECTD4 PRDM8 ARSA

1.43e-031541575EFO_0001645, EFO_0004623
Diseasebitter beverage consumption measurement

CUL3 ABCG2 FAM124B

1.46e-03421573EFO_0010089
DiseaseAutoimmune Diseases

RBP3 F8 C1S

1.46e-03421573C0004364
Diseaselevel of Ceramide (d40:1) in blood serum

CYP7A1 UBXN2B

1.50e-03111572OBA_2045185
Disease3-hydroxyanthranilate 3,4-dioxygenase measurement

CYP11B1 CYP11B2

1.50e-03111572EFO_0021862
Diseasehyperhomocysteinemia (implicated_via_orthology)

ECE1 F8

1.50e-03111572DOID:9279 (implicated_via_orthology)
Diseaseresponse to virus

BBS9 FREM2

1.50e-03111572GO_0009615
Diseasedermatomyositis

CYP11B1 PLCL1

1.79e-03121572EFO_0000398
Diseaselevel of Ceramide (d42:2) in blood serum

CYP7A1 UBXN2B

1.79e-03121572OBA_2045186
Diseasehypothyroidism (implicated_via_orthology)

DUOX1 ARSA

2.11e-03131572DOID:1459 (implicated_via_orthology)
Diseaseglycerophospholipid measurement

PGS1 GAL3ST1 PAQR5

2.28e-03491573EFO_0007630
DiseaseFEV/FEC ratio

JCAD NID2 SFRP2 CTTNBP2 VPS13C BACH2 NSD1 FREM2 EVA1B MYO1F UGGT2 RIPOR1 PLCL1 HERC1 MGA

2.39e-03122815715EFO_0004713
Diseasegallstones

ANPEP CYP7A1 UBXN2B LRBA

2.69e-031081574EFO_0004210
Diseaseneutrophil count

JCAD POGLUT3 AHI1 ZBTB16 CDC42BPA TSPOAP1 BACH2 HECTD4 NSD1 SLC9A1 LINGO1 TELO2 PAM PLCL1 LRBA DNMT1

2.93e-03138215716EFO_0004833
Diseaseapolipoprotein B measurement

EXOC6 CACNA2D1 PGS1 CYP7A1 ABCA8 KCTD6 PRDM8 LLGL1 UBXN2B SV2C

3.00e-0366315710EFO_0004615
DiseaseIntrahepatic cholestasis of pregnancy

CYP7A1 UBXN2B

3.21e-03161572EFO_0009048
Diseasepancreatitis

JCAD HECTD4

3.21e-03161572EFO_0000278
Diseaseoptic cup area measurement

CDC42BPA ATOH7 FAT3

3.33e-03561573EFO_0006940
Diseasecomplement factor H-related protein 1 measurement

CYP11B1 CYP11B2 KCNT2

3.33e-03561573EFO_0600054
Diseaseserum gamma-glutamyl transferase measurement

JCAD CDC42BPA DOCK11 CYP7A1 CYP11B1 HECTD4 TENM4 UBXN2B C1S CGNL1 LRBA DNMT1

3.67e-0391415712EFO_0004532
DiseaseColorectal Neoplasms

SFRP2 NRCAM ABCA8 TFRC MLH3 ABCG2

3.76e-032771576C0009404
Diseaseessential hypertension (is_implicated_in)

GRK4 ECE1

4.07e-03181572DOID:10825 (is_implicated_in)
DiseaseCannabis use initiation

UST LRRC7

4.07e-03181572EFO_0007586
DiseaseBMI-adjusted waist circumference, physical activity measurement

CPA5 NSD1 ITIH1 MYO1F

4.29e-031231574EFO_0007789, EFO_0008002
DiseaseColorectal Carcinoma

SFRP2 ACACA NRCAM RBP3 ABCA8 TFRC MLH3 PPM1F PAN2 ABCG2

4.48e-0370215710C0009402
Diseaserenovascular hypertension (biomarker_via_orthology)

SLC9A1 G6PD

4.53e-03191572DOID:1591 (biomarker_via_orthology)
Diseasecoronary artery disease

EXOC6 JCAD TRPC4AP HECTD4 ABCA8 GLMN PRDM8 ABHD5 STOML1 PAN2 C1S LRRC7 ABCG2 PLCL1

4.77e-03119415714EFO_0001645
Diseasetransient cerebral ischemia (implicated_via_orthology)

CBL HSF1 G6PD

4.86e-03641573DOID:224 (implicated_via_orthology)
Diseasehypertension (implicated_via_orthology)

CYP11B1 CYP11B2 ECE1 KYNU

4.94e-031281574DOID:10763 (implicated_via_orthology)
Diseaseresponse to ziprasidone

PPP3CA TENM4

5.02e-03201572GO_0097337
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ACACA TFRC G6PD

5.07e-03651573DOID:0080208 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NDAFLEFLPANFGRL

ERBIN

146

Q96RT1
LSFRQPYAGFVLNGI

EOLA1

6

Q8TE69
LSFRQPYAGFVLNGI

EOLA2

6

Q96DE9
EVTARGFGPLLQFAY

BACH2

81

Q9BYV9
PTFYGESGPQNRFEL

CDHR1

351

Q96JP9
SQGFPDTYRLFGNIL

DNMT1

1556

P26358
GGAYDEFIFAPRLDN

DNPEP

261

Q9ULA0
FNENFPYLLRGSDES

AHI1

426

Q8N157
LNRPGDAYGLQDLLF

CIITA

456

P33076
AYNNPADFFLDIING

ABCG2

286

Q9UNQ0
FFPGLNLEGYPNRDS

AASS

691

Q9UDR5
YRIGSFGPQEDLLFL

ACACA

1686

Q13085
SFGRNVFAISYIPGL

PAM

726

P19021
DDLARNGITGFPYFS

LINC00518

21

Q8N0U6
YALNVTGPILNFFAG

ANPEP

316

P15144
RGFFNGLRTELATYP

DHRS7

211

Q9Y394
IGFFGSNLPDYQRSE

EFR3A

386

Q14156
NYFPGLDLERRNAFG

ANKRD33B

176

A6NCL7
FTEAPVLNIQFRYGG

AP2A2

796

O94973
AEGAQQGDPLSRYIF

NAGK

221

Q9UJ70
VGEFPVLFFGSNDYL

NSD1

1791

Q96L73
GVASIYRGPFADENF

PPIH

86

O43447
FFLYIRPNLLEEGGN

OR5K2

256

Q8NHB8
YGELNGQRGLVPSNF

TSPOAP1

1811

O95153
FRDGLLPENTFIVGY

G6PD

56

P11413
SGIDNYGQGRNPFFL

INTS6L

106

Q5JSJ4
QPRQYFIGVLDIAGF

MYH7

451

P12883
FYRLFLFPGESAQNE

PAQR5

201

Q9NXK6
GQGFYLISPSEFERF

LLGL1

921

Q15334
TGLFEGQRNYLPNFI

PGM5

31

Q15124
LYAFGAERGNREPFL

DUOX1

231

Q9NRD9
FGPALERYSSFQVNG

PAN2

101

Q504Q3
TGFPQLQDGSLLYFF

OR6K3

31

Q8NGY3
NLAGFILLGFSDYPQ

OR2G2

11

Q8NGZ5
AINPEGLFYAASRQF

MCMDC2

521

Q4G0Z9
YEFANPSRLGEQRFG

HSPB2

16

Q16082
FQIIRGNFPYLSAFG

RASGRP2

451

Q7LDG7
GNFPYLSAFGDLDQN

RASGRP2

456

Q7LDG7
YNPFAKGFRDDGLNN

MGA

251

Q8IWI9
GRFPLYNLGFGHNVD

ITIH1

426

P19827
QGLNGDLYFSNVLPE

NRCAM

196

Q92823
NDAFLEFLPANFGRL

LRRC7

146

Q96NW7
FPGAFGELYTQNARA

GPC1

126

P35052
DGDGERLFQDLYPFI

JCAD

201

Q9P266
YVGISRNLDFAPGVN

FREM2

2061

Q5SZK8
GISLQQDPGALYDFN

HERC1

2911

Q15751
FELRDTGQYGFLLPA

CPA5

396

Q8WXQ8
DPLTGLNRGYAFVTF

SYNCRIP

196

O60506
GLFPRGADQEYSAFR

GRIA2

31

P42262
NDLPVLFELGEGSYF

HSF1

486

Q00613
LQSGGQPFDYSPIRF

PER2

386

O15055
TNDLDGAGIPFLDYR

PLXNA1

1311

Q9UIW2
GFLNINPFVEGSREY

LGALS12

181

Q96DT0
NPRFYGFRGEALANI

MLH3

86

Q9UHC1
YQILLASPEVNGFFG

PGS1

406

Q32NB8
VLNYRFDPLGIVDGF

FAM214A

886

Q32MH5
GGVQVLFPLFAQLDY

LRBA

471

P50851
DERFFPYANGTLGIR

L1CAM

471

P32004
GQLAVVEPYAFRGLN

LINGO1

321

Q96FE5
LPNLDGLIAGYARNF

GABRD

41

O14764
GAYAPVLQDFRSLND

F8

1261

P00451
PTDSFPGLDQFRGNY

FMO6P

156

O60774
QLAAGGLRFTDFYVP

ARSA

51

P15289
ETAGNGLYNFIVPLR

KCNT2

726

Q6UVM3
LLNLRPDDFVFYVGG

LAMA5

2866

O15230
RANFGSRPFAYAEGQ

HECTD4

2126

Q9Y4D8
LFDTQGSPGLEDYFN

HECTD4

3221

Q9Y4D8
DTLQGYGFPVNRLFD

EXOC6

401

Q8TAG9
QESYAFGRFLPGFLL

BBS9

166

Q3SYG4
SGNPIYDFFLGRELN

TM7SF2

166

O76062
GAPGEQENRGAVYLF

ITGAD

541

Q13349
LFLYPANGLQFLGTR

NID2

196

Q14112
NLLFFDLGYDNSLDP

GAL3ST1

216

Q99999
NSEPRQTYFGGFPRD

FAM124B

371

Q9H5Z6
IRANPESFGLYFVLG

EVA1B

21

Q9NVM1
NAGPLAYARAFLNDS

DOCK11

1956

Q5JSL3
NNFEFFRPLVEGLGY

SDR42E1

261

Q8WUS8
LRNGYAPVEFFLEGT

GNPAT

231

O15228
DYTNQIGRFFGEIDP

CACNA2D1

866

P54289
SAFPFGLQGNSEYLI

CGNL1

391

Q0VF96
NDPFLALQRDYEAGA

CTTNBP2

81

Q8WZ74
REFFFELGLYDPGLQ

GALNT7

396

Q86SF2
AGDFEYFLNLNSRSP

CUL3

371

Q13618
FELRDTGTYGFLLPA

CPA4

381

Q9UI42
ISGNELGFFYLNPDS

FAT3

616

Q8TDW7
LGFFYLNPDSGVLQL

FAT3

621

Q8TDW7
PGVYNFNGSRDLIAF

GLB1L

91

Q6UWU2
AFLRQGQLPDTELGY

GPAT2

706

Q6NUI2
GESELYSQRLFGFQP

ATOH7

131

Q8N100
DSLVFVAGDRQFGPY

C1S

236

P09871
TFQELGPIFRYDLGG

CYP11B1

71

P15538
LEAFLYNFSQPGGLT

EPHX3

261

Q9H6B9
ANFILAYQFRPDGAS

FBXW4

136

P57775
DPQGNYFIDRDGPLF

KCTD6

51

Q8NC69
QALIDGFREGFYLFP

CBL

326

P22681
GFREGFYLFPDGRNQ

CBL

331

P22681
YLGCALQFGANPLEF

CYP7A1

41

P22680
TFQELGPIFRYNLGG

CYP11B2

71

P19099
DQSGLGLPSRDYYLN

ECE1

256

P42892
IYNLGNPGFDEQRAV

GRK4

276

P32298
YPGGAENGRLLDFEF

H6PD

501

O95479
FEVGGSPANTRYLFL

PPP3CB

111

P16298
LIGPDGEFLDYFGQN

SCO1

266

O75880
ELDRNYLNYGEEGAP

CHGB

466

P05060
EGPFFRDYALNVFVG

IZUMO2

61

Q6UXV1
LFEVGGSPANTRYLF

PPP3CA

101

Q08209
QLFGLSDPVNRAYFA

PPM1F

181

P49593
EFILLGFSNYPELQG

OR10A6

11

Q8NH74
RGNPVFQLAAEYGLL

PAOX

76

Q6QHF9
EGGNDPFRYFASEII

GLMN

231

Q92990
SYFVRLGDLGPSFRQ

PLIN4

1176

Q96Q06
SVYGSGQRAFDLFNP

MRPS23

76

Q9Y3D9
GRTLDSDYAPLQQFF

RUFY3

91

Q7L099
SARGLFLFGQPDFSY

SFRP2

21

Q96HF1
LYPTDRRATGFGFLN

SV2C

661

Q496J9
PNTYIFDLFGGVDLL

TRPC4AP

126

Q8TEL6
GVNDTDFRVYLLGNP

POMT2

581

Q9UKY4
NFSGGEPFLQDRGEY

RSAD2

121

Q8WXG1
YFGLEENGRLFAPPS

PRDM8

361

Q9NQV8
LNFLTPLRNFIEGDY

SH3GLB1

141

Q9Y371
LAEFFPQNYFRLLGE

TELO2

176

Q9Y4R8
FQSGFLRYPLNGEGN

CDC42BPA

1376

Q5VT25
RSAFSNLFGGEPLSY

TFRC

6

P02786
NLFGGEPLSYTRFSL

TFRC

11

P02786
GLLLDRTNFYAEQGG

AARS2

556

Q5JTZ9
LENGQDNPIGFLAYI

ABCA8

1011

O94911
NRPVYAFDLLGFGRS

ABHD5

101

Q8WTS1
GPSGRNTEYLFELAN

CHAC2

136

Q8WUX2
DTVFLGPGLLFLDQY

CHPT1

326

Q8WUD6
GPGLLFLDQYFNNFI

CHPT1

331

Q8WUD6
NGNEFYLGNSLLDSP

C12orf56

246

Q8IXR9
QAYSAFLRSPEGAGF

PITPNM1

541

O00562
ENPQLLDAGITGYFF

POGLUT3

331

Q7Z4H8
FLNFSRFGGDQPVYI

UST

171

Q9Y2C2
NTPLSLTFEAYRFGG

PLEKHG5

126

O94827
YLIEDQFRGPADING

PLCL1

416

Q15111
NYPGFLTILRATGFD

THOC2

1066

Q8NI27
NGFSLDDGELRPYNE

UBXN2B

151

Q14CS0
YGGLLPQGFIQRELF

ZBTB16

371

Q05516
PGNVGYLRFDSFADA

RBP3

436

P10745
AIFNEVAPGYFSRDG

SECTM1

76

Q8WVN6
NGGLYKRPFNEAFEE

SPTLC2

51

O15270
GYRALPLGDFDRFQQ

STOML1

6

Q9UBI4
TFDPYLGGRNFDEAL

HSPA4L

226

O95757
SPFLVEQFQEYFLGG

GPLD1

236

P80108
GDQPLFRGADRYDFA

TMED6

31

Q8WW62
NPLFGYTISRQDGSF

TENM4

946

Q6N022
LDAGYFLPLRQFTEN

SLC9A1

171

P19634
INNEVLRNGGSPAFY

TEX13C

21

A0A0J9YWL9
GNEVFRFNLDLYPDA

VPS13C

1151

Q709C8
ALAFPRAFQGLLDTY

NAPRT

276

Q6XQN6
LYNRFDLELFTPGNL

PRRG4

51

Q9BZD6
NVSFILDNDYGRSFP

PKHD1L1

236

Q86WI1
LFIGGLPNYLNDDQV

U2AF2

261

P26368
SIGNGVADFFRLPYE

VPS13B

3666

Q7Z7G8
AEGGYPLRFSTLFQE

ZNF510

21

Q9Y2H8
NVLREFSGYPGLLNG

WDR89

61

Q96FK6
NGRFLGPLDEDFYAE

UGGT2

876

Q9NYU1
EPQLREENDLGLFGY

XPC

721

Q01831
RPLGQVGVFLDYDNG

TRIM64

401

A6NGJ6
GLEFLIYFQGNSAPD

TRBV7-2

61

A0A1B0GXF2
DDYRGQFPELQGLEQ

RIPOR1

806

Q6ZS17
VPRGRLFAFDSEGNY

WDR91

666

A4D1P6
ALIVGFDFDGTPRLY

PSMA7

131

O14818
PGYGFLSERADFAQA

PC

116

P11498
RFSNGFIQFLGEPYR

PRO1933

71

Q9H354
DGFFPSELQRLYPNG

UBXN11

266

Q5T124
RDLYRSGYGFNEPEQ

ZNF326

86

Q5BKZ1
EQGYELQFRLGPTLQ

AGL

26

P35573
ENAIYFLGNSLGLQP

KYNU

66

Q16719
FLGDQRFSYGQPLIL

LAMC3

546

Q9Y6N6
NRNFVGDYLGLEERP

MYO1F

736

O00160
AQALLRDYGFLPELG

GRIN2D

331

O15399