Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH17 KIFC3 DNAH11

2.80e-06181134GO:0008569
GeneOntologyMolecularFunctiondystroglycan binding

DAG1 DMD VCL

3.74e-05121133GO:0002162
GeneOntologyCellularComponentnuclear pore outer ring

NUP85 NUP160 SEC13

1.89e-05101153GO:0031080
GeneOntologyCellularComponentpostsynaptic membrane

GABRP SUSD4 HTR3A DAG1 GRM3 CHRNA7 CHRND LRRTM4 DGKI DMD

8.15e-0540511510GO:0045211
GeneOntologyCellularComponentcostamere

DAG1 DMD VCL

2.31e-04221153GO:0043034
GeneOntologyCellularComponentsynaptic membrane

GABRP SUSD4 HTR3A DAG1 GRM3 CHRNA7 CHRND LRRTM4 MTMR2 DGKI DMD

3.75e-0458311511GO:0097060
DomainNCD3G

CASR GRM3 TAS1R1

5.75e-05131123PF07562
DomainGPCR_3_9-Cys_dom

CASR GRM3 TAS1R1

5.75e-05131123IPR011500
DomainGPCR_3_CS

CASR GRM3 TAS1R1

7.28e-05141123IPR017979
DomainPpantetheine_attach_site

FASN ALDH1L2

1.07e-0431122IPR006162
DomainNeurotransmitter_ion_chnl_CS

GABRP HTR3A CHRNA7 CHRND

1.51e-04451124IPR018000
DomainNeur_chan_memb

GABRP HTR3A CHRNA7 CHRND

1.65e-04461124PF02932
DomainNeurotrans-gated_channel_TM

GABRP HTR3A CHRNA7 CHRND

1.79e-04471124IPR006029
Domain-

GABRP HTR3A CHRNA7 CHRND

1.79e-044711242.70.170.10
DomainNeur_chan_LBD

GABRP HTR3A CHRNA7 CHRND

1.79e-04471124PF02931
DomainNEUROTR_ION_CHANNEL

GABRP HTR3A CHRNA7 CHRND

1.79e-04471124PS00236
DomainNeur_channel

GABRP HTR3A CHRNA7 CHRND

1.79e-04471124IPR006201
DomainNeur_chan_lig-bd

GABRP HTR3A CHRNA7 CHRND

1.79e-04471124IPR006202
Domain-

FSTL5 EML6 BIRC6 WDR38 WDR12 WDR73 EIF3B HERC1 SEC13

1.79e-0433311292.130.10.10
DomainWD40/YVTN_repeat-like_dom

FSTL5 EML6 BIRC6 WDR38 WDR12 WDR73 EIF3B HERC1 SEC13

1.88e-043351129IPR015943
DomainGPCR_3

CASR GRM3 TAS1R1

2.58e-04211123IPR000337
Domain7tm_3

CASR GRM3 TAS1R1

2.97e-04221123PF00003
DomainG_PROTEIN_RECEP_F3_2

CASR GRM3 TAS1R1

2.97e-04221123PS00980
DomainG_PROTEIN_RECEP_F3_3

CASR GRM3 TAS1R1

2.97e-04221123PS00981
DomainG_PROTEIN_RECEP_F3_1

CASR GRM3 TAS1R1

2.97e-04221123PS00979
DomainG_PROTEIN_RECEP_F3_4

CASR GRM3 TAS1R1

2.97e-04221123PS50259
DomainGPCR_3_C

CASR GRM3 TAS1R1

2.97e-04221123IPR017978
Domain-

HTR3A CHRNA7 CHRND

3.41e-042311231.20.120.370
DomainAcetylcholine_rcpt_TM

HTR3A CHRNA7 CHRND

3.41e-04231123IPR027361
Domain-

FASN ALDH1L2

3.52e-04511221.10.1200.10
DomainPHOSPHOPANTETHEINE

FASN ALDH1L2

3.52e-0451122PS00012
DomainPP-binding

FASN ALDH1L2

3.52e-0451122PF00550
DomainACP_DOMAIN

FASN ALDH1L2

3.52e-0451122PS50075
DomainPP-bd_ACP

FASN ALDH1L2

5.26e-0461122IPR009081
DomainANF_lig-bd_rcpt

CASR GRM3 TAS1R1

1.41e-03371123IPR001828
DomainANF_receptor

CASR GRM3 TAS1R1

1.41e-03371123PF01094
DomainWD_REPEATS_1

EML6 WDR38 WDR12 WDR73 EIF3B HERC1 SEC13

1.44e-032781127PS00678
DomainWD_REPEATS_2

EML6 WDR38 WDR12 WDR73 EIF3B HERC1 SEC13

1.47e-032791127PS50082
DomainWD_REPEATS_REGION

EML6 WDR38 WDR12 WDR73 EIF3B HERC1 SEC13

1.47e-032791127PS50294
DomainPeripla_BP_I

CASR GRM3 TAS1R1

1.64e-03391123IPR028082
Domain-

GAK MTMR1 STYXL2 MTMR2

2.28e-039211243.90.190.10
DomainKelch_2

KLHDC2 ATRNL1

2.66e-03131122IPR011498
DomainKelch_2

KLHDC2 ATRNL1

2.66e-03131122PF07646
DomainProt-tyrosine_phosphatase-like

GAK MTMR1 STYXL2 MTMR2

2.98e-03991124IPR029021
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH11

3.09e-03141122IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH11

3.09e-03141122IPR024743
DomainMyotubularin-like_Pase_dom

MTMR1 MTMR2

3.09e-03141122IPR010569
Domain-

NAGA FUCA2

3.09e-031411222.60.40.1180
DomainMT

DNAH14 DNAH11

3.09e-03141122PF12777
DomainAAA_8

DNAH14 DNAH11

3.09e-03141122PF12780
DomainPPASE_MYOTUBULARIN

MTMR1 MTMR2

3.09e-03141122PS51339
DomainMyotubularin_fam

MTMR1 MTMR2

3.09e-03141122IPR030564
DomainMyotub-related

MTMR1 MTMR2

3.09e-03141122PF06602
DomainDHC_fam

DNAH14 DNAH11

3.56e-03151122IPR026983
DomainDynein_heavy

DNAH14 DNAH11

3.56e-03151122PF03028
DomainGlyco_hydro_b

NAGA FUCA2

3.56e-03151122IPR013780
DomainDynein_heavy_dom

DNAH14 DNAH11

3.56e-03151122IPR004273
DomainGlycoside_hydrolase_SF

NAGA FUCA2 GAA

3.95e-03531123IPR017853
DomainGRAM

MTMR1 MTMR2

4.05e-03161122SM00568
DomainNicotinic_acetylcholine_rcpt

CHRNA7 CHRND

4.05e-03161122IPR002394
DomainAcyl_Trfase/lysoPLipase

FASN PLA2G4C

4.57e-03171122IPR016035
DomainWD40

EML6 WDR38 WDR12 WDR73 HERC1 SEC13

4.72e-032591126PF00400
DomainWD40

EML6 WDR38 WDR12 WDR73 HERC1 SEC13

5.56e-032681126SM00320
DomainWD40_repeat

EML6 WDR38 WDR12 WDR73 HERC1 SEC13

5.97e-032721126IPR001680
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

CASR GRM3 TAS2R3 TAS1R1 TAS2R20

1.84e-0637795MM15067
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

CASR GRM3 TAS2R3 TAS1R1 TAS2R20

2.41e-0639795M793
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 NUP85 MYCBP2 POLG ANKLE1 BIRC6 HDAC7 LDLR KANSL3 FASN CANT1 PCNX4 SUMF1 KIFC3 HERC1 EVI5L

8.57e-0711051161635748872
Pubmed

Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.

NUP85 NUP160 SEC13

2.99e-069116317360435
Pubmed

The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.

CASR GRM3 TAS1R1

4.26e-0610116317156446
Pubmed

The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

NUP85 NUP160 SEC13

4.26e-0610116315146057
Pubmed

The discovery of a Werner Helicase Interacting Protein (WHIP) association with the nuclear pore complex.

NUP85 NUP160 SEC13

4.26e-0610116320676042
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

AUP1 PEG10 BIRC6 HDAC7 ALDH1L2 SUMF1 GIGYF2 KIFC3 HERC1 TOP1MT IKBKB

6.00e-066041161138803224
Pubmed

α-Dystroglycan hypoglycosylation affects cell migration by influencing β-dystroglycan membrane clustering and filopodia length: A multiscale confocal microscopy analysis.

DAG1 DMD

1.10e-052116228572004
Pubmed

Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.

DAG1 DMD

1.10e-052116210932245
Pubmed

Disruption of sarcolemmal dystrophin and beta-dystroglycan may be a potential mechanism for myocardial dysfunction in severe sepsis.

DAG1 DMD

1.10e-052116220142806
Pubmed

IKKβ links vascular inflammation to obesity and atherosclerosis.

LDLR IKBKB

1.10e-052116224799533
Pubmed

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.

DMD IKBKB

1.10e-052116230143619
Pubmed

The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture.

NUP85 NUP160

1.10e-052116219576787
Pubmed

Exogenous Dp71 restores the levels of dystrophin associated proteins but does not alleviate muscle damage in mdx mice.

DAG1 DMD

1.10e-05211627894483
Pubmed

The WW domain of dystrophin requires EF-hands region to interact with beta-dystroglycan.

DAG1 DMD

1.10e-052116210355629
Pubmed

Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells.

DAG1 DMD

1.10e-052116232982691
Pubmed

Lack of dystrophin leads to the selective loss of superior cervical ganglion neurons projecting to muscular targets in genetically dystrophic mdx mice.

DAG1 DMD

1.10e-052116216023353
Pubmed

What do mouse models of muscular dystrophy tell us about the DAPC and its components?

DAG1 DMD

1.10e-052116225270874
Pubmed

Desensitization characteristics of the human alpha7nAChR/5HT3A chimera receptor.

HTR3A CHRNA7

1.10e-052116217192651
Pubmed

Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse.

DAG1 DMD

1.10e-052116222810924
Pubmed

Role of mental retardation-associated dystrophin-gene product Dp71 in excitatory synapse organization, synaptic plasticity and behavioral functions.

DAG1 DMD

1.10e-052116219649270
Pubmed

Exogenous Dp71 is a dominant negative competitor of dystrophin in skeletal muscle.

DAG1 DMD

1.10e-052116212398834
Pubmed

Functional implication of Dp71 in osmoregulation and vascular permeability of the retina.

DAG1 DMD

1.10e-052116219809515
Pubmed

Identification and characterization of the dystrophin anchoring site on beta-dystroglycan.

DAG1 DMD

1.10e-05211627592992
Pubmed

Dystroglycan contributes to the formation of multiple dystrophin-like complexes in brain.

DAG1 DMD

1.10e-052116211520903
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

NUP85 FAN1 AATF EIF3B TOP1MT NUP160 VCL

2.18e-05250116733536335
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

CAD NUP85 AUP1 MTMR1 BIRC6 FASN WDR73 EIF3B NUP160 SEC13

2.26e-055711161037167062
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NUP85 PEG10 DPP8 BIRC6 LAP3 FASN JMJD6 PSMG1 MTMR2 WDR12 EIF3B HERC1 IKBKB NUP160 VCL SEC13

2.73e-0514551161622863883
Pubmed

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

ARPP21 LAP3 EPG5 SACS JMJD8

2.80e-05105116523284306
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CPA4 GAK CAD HSP90AB4P MYCBP2 PEG10 BIRC6 LDLR FASN TMTC3 PSMG1 WDR12 IKBKB NUP160 GAA

2.80e-0512971161533545068
Pubmed

N-terminal α Dystroglycan (αDG-N): A Potential Serum Biomarker for Duchenne Muscular Dystrophy.

DAG1 DMD

3.30e-053116227854211
Pubmed

A new look at cytoskeletal NOS-1 and β-dystroglycan changes in developing muscle and brain in control and mdx dystrophic mice.

DAG1 DMD

3.30e-053116223940011
Pubmed

Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.

CHRNA7 DMD

3.30e-053116224833065
Pubmed

α7 Nicotinic acetylcholine receptor is expressed in human atherosclerosis and inhibits disease in mice--brief report.

LDLR CHRNA7

3.30e-053116225324572
Pubmed

Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.

DAG1 DMD

3.30e-053116225324540
Pubmed

Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.

DAG1 DMD

3.30e-053116211741881
Pubmed

Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors.

HTR3A CHRNA7

3.30e-053116215927954
Pubmed

Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy.

DAG1 DMD

3.30e-053116214678011
Pubmed

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

DAG1 DMD

3.30e-05311621757468
Pubmed

Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.

DMD VCL

3.30e-053116215128702
Pubmed

Deletion of Galgt2 (B4Galnt2) reduces muscle growth in response to acute injury and increases muscle inflammation and pathology in dystrophin-deficient mice.

DAG1 DMD

3.30e-053116226435413
Pubmed

Platelet IκB kinase-β deficiency increases mouse arterial neointima formation via delayed glycoprotein Ibα shedding.

LDLR IKBKB

3.30e-053116223241410
Pubmed

Intermittent hypoxia and hypercapnia induces inhibitor of nuclear factor-κB kinase subunit β-dependent atherosclerosis in pulmonary arteries.

LDLR IKBKB

3.30e-053116231618063
Pubmed

Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice.

LDLR IKBKB

3.30e-053116223023371
Pubmed

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

LDLR IKBKB

3.30e-053116214561702
Pubmed

Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle.

DMD GAA

3.30e-053116220413686
Pubmed

Reduced size and macrophage content of advanced atherosclerotic lesions in mice with bone marrow specific deficiency of alpha 7 nicotinic acetylcholine receptor.

LDLR CHRNA7

3.30e-053116225826262
Pubmed

Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder.

CHRNA7 FAN1

3.30e-053116226658876
Pubmed

Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting.

DAG1 DMD

3.30e-053116225082828
Pubmed

Dystroglycan mRNA expression during normal and mdx mouse embryogenesis: a comparison with utrophin and the apo-dystrophins.

DAG1 DMD

3.30e-05311628589441
Pubmed

Hematopoietic α7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis.

LDLR CHRNA7

3.30e-053116225345495
Pubmed

Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.

DMD VCL

3.30e-053116212711699
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

CAD NUP85 RBL1 TMEM214 FASN COG1 PCNX4 IRAG2 DMD NUP160 SEC13

4.62e-057541161135906200
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC3 STIM2 MYCBP2 NAGA DAG1 ALG11 TMEM214 LDLR TMTC3 CANT1 PSMG1 JMJD8 SUMF1 FUCA2

4.86e-0512011161435696571
Pubmed

Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein.

DAG1 DMD

6.59e-054116211717465
Pubmed

Local proliferation dominates lesional macrophage accumulation in atherosclerosis.

LDLR CSF2RB

6.59e-054116223933982
Pubmed

Functional redundancy in the myotubularin family.

MTMR1 MTMR2

6.59e-054116211846405
Pubmed

Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.

DAG1 DMD

6.59e-054116211259414
Pubmed

Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensable for their differentiation.

DAG1 DMD

6.59e-054116212040032
Pubmed

Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases.

MTMR1 MTMR2

6.59e-054116212925573
Pubmed

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.

CSF2RB DGKI

6.59e-054116219065143
Pubmed

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.

NUP85 NUP160

6.59e-054116230179222
Pubmed

Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels.

STIM2 CASR

6.59e-054116232186932
Pubmed

Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.

DAG1 DMD

6.59e-054116217389230
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAD MYCBP2 BIRC6 FASN GIGYF2 AATF WDR12 NUP160 VCL SEC13

6.96e-056531161022586326
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

EML6 MTMR1 TEK LRRTM4 MTMR2 GIGYF2 EIF3B HERC1

8.63e-05420116828065597
Pubmed

BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells.

STIM2 IKBKB

1.10e-045116232294437
Pubmed

Role of dystrophins and utrophins in platelet adhesion process.

DMD VCL

1.10e-045116216803572
Pubmed

Foot pad skin biopsy in mouse models of hereditary neuropathy.

DAG1 MTMR2

1.10e-045116220878767
Pubmed

Dp71 gene disruption alters the composition of the dystrophin-associated protein complex and neuronal nitric oxide synthase expression in the hypothalamic supraoptic and paraventricular nuclei.

DAG1 DMD

1.10e-045116222493004
Pubmed

Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.

DAG1 DMD

1.10e-045116211430802
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

DAG1 DMD

1.10e-045116219109891
Pubmed

Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study.

DGKI DNAH11

1.10e-045116224468470
Pubmed

Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation.

DAG1 DMD

1.10e-045116217993586
Pubmed

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.

MTMR1 MTMR2

1.10e-04511628640223
Pubmed

NF-κB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia.

DMD IKBKB

1.10e-045116224084740
Pubmed

Dystroglycan mediates homeostatic synaptic plasticity at GABAergic synapses.

DAG1 DMD

1.10e-045116224753587
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

NUP85 NUP160 SEC13

1.37e-0430116324315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

NUP85 NUP160 SEC13

1.37e-0430116327016207
Pubmed

Maternal synchronization of gestational length and lung maturation.

ABCA3 TEK FASN

1.52e-0431116322096492
Pubmed

Fukutin-related protein associates with the sarcolemmal dystrophin-glycoprotein complex.

DAG1 DMD

1.64e-046116217452335
Pubmed

Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy.

DMD IKBKB

1.64e-046116217380205
Pubmed

TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.

DMD IKBKB

1.64e-046116220814569
Pubmed

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.

POLG FASN

1.64e-046116231358769
Pubmed

Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb.

RBL1 AATF

1.64e-046116212450794
Pubmed

Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse.

DAG1 DMD

1.64e-04611629245586
Pubmed

15q13.3 Recurrent Deletion

CHRNA7 FAN1

1.64e-046116221290787
Pubmed

Interactions between dystrophin glycoprotein complex proteins.

DAG1 DMD

1.64e-04611627547961
Pubmed

Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion.

CHRNA7 DMD

1.64e-046116212079404
Pubmed

GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta.

CSF2RB IKBKB

1.64e-046116212637324
Pubmed

Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex.

DAG1 DMD

1.64e-046116210767429
Pubmed

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.

NUP85 POLG ITPKC

1.67e-0432116326142281
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

CAD MYCBP2 HERC1 IKBKB

1.93e-0485116416051665
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

CAD NUP85 AUP1 NAGA TMEM214 FASN EIF3B FUCA2 GAA

2.22e-04613116922268729
Pubmed

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.

DAG1 DMD

2.29e-04711621461282
Pubmed

Phosphoinositide 3-kinase p85beta regulates invadopodium formation.

PIK3R2 VCL

2.29e-047116225217619
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

DNAH17 DNAH11

2.29e-047116233139725
Pubmed

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.

HDAC7 LDLR

2.29e-047116212970571
Pubmed

Embryo implantation in mouse: fetomaternal coordination in the pattern of expression of uPA, uPAR, PAI-1 and alpha 2MR/LRP genes.

TEK LDLR

2.29e-04711628798151
Pubmed

The cellular prion protein colocalizes with the dystroglycan complex in the brain.

DAG1 DMD

2.29e-047116211032878
Pubmed

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

DMD VCL

2.29e-047116223266827
CytobandEnsembl 112 genes in cytogenetic band chr17q25

NUP85 LRRC45 FASN COG1 CANT1 JMJD6 DNAH17 GAA

1.24e-063071168chr17q25
CytobandEnsembl 112 genes in cytogenetic band chr19p13

SIN3B CPAMD8 ACER1 ZNF559 ANKLE1 TMEM205 LDLR PIK3R2 EVI5L

2.00e-047971169chr19p13
GeneFamilyDyneins, axonemal

DNAH14 DNAH17 DNAH11

4.12e-0517733536
GeneFamilyNucleoporins

NUP85 NUP160 SEC13

2.88e-04327331051
GeneFamilyWD repeat domain containing

EML6 WDR38 WDR12 WDR73 HERC1 SEC13

6.61e-04262736362
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR1 MTMR2

1.63e-0315732903
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA7 CHRND

1.86e-0316732173
GeneFamilyFibronectin type III domain containing

TEK IGDCC4 CSF2RB CNTFR

4.00e-03160734555
CoexpressionGSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP

CAD PEG10 DPP8 TMTC3 PIK3R2 NUP160 CNTFR

1.92e-051871157M6807
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN

ABCC3 RBL1 FASN IRAG2 IKBKB NUP160 VCL

2.96e-052001157M5212
CoexpressionGSE17721_CTRL_VS_POLYIC_12H_BMDC_UP

ABCC3 MYCBP2 POLG MTMR1 FASN FUCA2 HERC1

2.96e-052001157M3719
CoexpressionGSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP

ABCC3 ABCA3 SUMF1 IRAG2 FUCA2 DMD VCL

2.96e-052001157M6888
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR3A PEG10 EML6 C3orf20 CHRND IRAG2

4.25e-0616211663e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML6 CSF2RB IRAG2 DGKI LY75 EDRF1

4.89e-0616611660a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_F|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CPA4 CHST5 SERPINE3 CAD FJX1 PQBP1

5.60e-06170116671718dcebd48105994c313bb55babc70301170a0
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

C2orf69 DAG1 ANKRD50 BIRC6 GIGYF2 CPLANE1

1.16e-051931166abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PEG10 DAG1 CHRND IGDCC4 TMEM47 DMD

1.38e-051991166e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PEG10 DAG1 CHRND IGDCC4 TMEM47 DMD

1.38e-051991166801887db51ac5dc5b068808ff75e3a46643398e9
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-052001166f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-052001166cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-052001166c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-0520011664fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-052001166310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SUSD4 ARPP21 TEK ATRNL1 LRRTM4 DGKI

1.41e-052001166961858738ce35db8760c8c2e136f8369bc444ccf
DiseaseDuchenne muscular dystrophy (is_implicated_in)

DAG1 DMD

3.90e-0531072DOID:11723 (is_implicated_in)
DiseaseCardiomyopathies

POLG EPG5 DMD GAA VCL

1.14e-041301075C0878544
DiseaseDuchenne muscular dystrophy (is_marker_for)

DAG1 DMD

1.29e-0451072DOID:11723 (is_marker_for)
Diseasepulmonary alveolar proteinosis (implicated_via_orthology)

ABCA3 CSF2RB

1.29e-0451072DOID:12120 (implicated_via_orthology)
Diseaseacute kidney tubular necrosis (biomarker_via_orthology)

TEK BMP7

1.29e-0451072DOID:12556 (biomarker_via_orthology)
Diseaseimmunoglobulin superfamily DCC subclass member 4 measurement

DPP8 IGDCC4

1.29e-0451072EFO_0801690
DiseaseMental deterioration

TEK DGKI DNAH11

1.58e-04291073HP_0001268
Diseasemuscular atrophy (biomarker_via_orthology)

HSP90AB4P DAG1 DMD

1.58e-04291073DOID:767 (biomarker_via_orthology)
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NUP85 NUP160 PLCE1

1.75e-04301073C1868672
Diseasebrain disease (implicated_via_orthology)

STIM2 MYCBP2

1.94e-0461072DOID:936 (implicated_via_orthology)
Diseasepulmonary alveolar proteinosis (is_implicated_in)

ABCA3 CSF2RB

1.94e-0461072DOID:12120 (is_implicated_in)
Diseaseworry measurement

ARPP21 TMEM241 MYCBP2 GRM3 MTMR2

2.51e-041541075EFO_0009589
DiseaseVentricular Dysfunction

DMD GAA

3.60e-0481072C0242973
Diseasecentronuclear myopathy X-linked (implicated_via_orthology)

MTMR1 MTMR2

4.61e-0491072DOID:0111225 (implicated_via_orthology)
Diseasehepatocellular carcinoma (biomarker_via_orthology)

ABCC3 CAD TEK PIK3R2

6.56e-041081074DOID:684 (biomarker_via_orthology)
Diseaseurokinase-type plasminogen activator measurement

LY75 VCL

7.01e-04111072EFO_0010803
DiseaseCardiomyopathy, Dilated

FASN WDR12 DMD

7.12e-04481073C0007193
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRP SIN3B GIGYF2

7.57e-04491073DOID:0060037 (implicated_via_orthology)
DiseaseCardiomyopathy, Familial Idiopathic

FASN WDR12 DMD

8.03e-04501073C1449563
DiseaseColorectal Carcinoma

ABCC3 CPAMD8 ABCA3 CAD FSTL5 PQBP1 SACS DMD EDRF1

1.05e-037021079C0009402
Diseaseurokinase plasminogen activator surface receptor measurement

LY75 VCL

1.15e-03141072EFO_0010932
DiseaseHypertrophic Cardiomyopathy

FASN GAA VCL

1.18e-03571073C0007194
Diseasemitochondrial DNA measurement

SERPINE3 POLG ANKLE1 LDLR TOP1MT LY75

1.27e-033281076EFO_0006312
Diseasecortex volume change measurement

SUMF1 LRRTM4

1.33e-03151072EFO_0021500
Diseasenon-lobar intracerebral hemorrhage

DNAH14 WDR12 NUP160

1.57e-03631073EFO_0010178
Diseaseattention deficit hyperactivity disorder, schizophrenia

GRM3 DGKI GIGYF2

1.64e-03641073EFO_0003888, MONDO_0005090
Diseasecognitive function measurement, self reported educational attainment

ARPP21 MYCBP2 DPP8 BIRC6 MTMR2 NUP160

1.90e-033551076EFO_0004784, EFO_0008354
Diseasesusceptibility to mononucleosis measurement

ANKRD50 HDAC7 DMD

2.04e-03691073EFO_0008403
Diseasethrombin activatable fibrinolysis inhibitor activation peptide measurement

OTOA ARPP21

2.14e-03191072EFO_0008582
Diseasecortisol measurement

LDLR BMP7

2.37e-03201072EFO_0005843
Diseasekidney disease (biomarker_via_orthology)

ABCC3 BMP7

2.62e-03211072DOID:557 (biomarker_via_orthology)
Diseasemuscular dystrophy (implicated_via_orthology)

DAG1 DMD

2.62e-03211072DOID:9884 (implicated_via_orthology)
Diseasemucocutaneous lymph node syndrome

STIM2 EPG5 ITPKC

2.69e-03761073EFO_0004246
Diseasedilated cardiomyopathy (implicated_via_orthology)

STIM2 DAG1 DMD

3.11e-03801073DOID:12930 (implicated_via_orthology)
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM3 TEK

3.14e-03231072C0393672
DiseaseEpilepsy, Lateral Temporal

GRM3 TEK

3.14e-03231072C0393682
DiseaseUncinate Epilepsy

GRM3 TEK

3.14e-03231072C0014558
DiseaseEpilepsy, Temporal Lobe

GRM3 TEK

3.14e-03231072C0014556
DiseaseCoronary heart disease

LDLR DNAH11

3.41e-03241072C0010068
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR1 MTMR2

3.41e-03241072DOID:10595 (implicated_via_orthology)
DiseaseNephritis, Interstitial

SLC16A12 FAN1

3.41e-03241072C0027707
DiseaseDyslipidemias

LDLR DNAH11

3.41e-03241072C0242339
DiseaseDyslipoproteinemias

LDLR DNAH11

3.41e-03241072C0598784
Diseasecarotid plaque build

EPG5 ATRNL1 LRRTM4

3.57e-03841073EFO_0006501

Protein segments in the cluster

PeptideGeneStartEntry
LRWWATSASNDSLLE

nan

121

A8MVM7
VNSSWTLNHILSLWK

ALG11

256

Q2TAA5
SSNLSHLEEDTWILW

EVI5L

76

Q96CN4
NWVSVLSDAWNSSPH

EPG5

2096

Q9HCE0
ETLTTNVWIEHGWTD

CHRND

71

Q07001
WHSWVGALTLLATAV

CYB561D1

126

Q8N8Q1
VVTSVSWWSHKVDNA

EIF3B

666

P55884
WEHQTSIDSDMATLW

ANKLE1

321

Q8NAG6
TWKLQTDSNSWDEHV

BIRC6

1076

Q9NR09
WENWSLENVATILAH

C2orf69

126

Q8N8R5
SVVLWAVALTSWISD

ACER1

176

Q8TDN7
KIWLASEAWASSSLI

CASR

291

P41180
AEISWDQSAEVLHNW

ALDH1L2

231

Q3SY69
WAETLSLDVNSIHWS

GRM3

486

Q14832
TSWLHTIQDINISLW

HTR3A

176

P46098
AIDEQLTAATTWLTW

DNAH11

791

Q96DT5
VHVASFWLSALLWDL

ABCA3

1136

Q99758
HTDQDGWTALRSAAW

ANKRD50

606

Q9ULJ7
NRAWTELTDWLSLLD

DMD

2476

P11532
EGWLVFDITATSNHW

BMP7

221

P18075
SGWLHNTSSWLASSL

BBS12

566

Q6ZW61
NELKWSDHQRAWSST

ARPP21

351

Q9UBL0
VLTTNIWLQMSWTDH

CHRNA7

71

P36544
VHAESNSSTSIWLRW

IGDCC4

756

Q8TDY8
DEARWLSNVDGTHWL

MTMR1

396

Q13613
RTHLEWSWSELETTC

ITPKC

121

Q96DU7
WWALELSHLHTFVSS

ABCC3

1396

O15438
SSWLWNKLFEASIET

LAP3

411

P28838
TDDSASWVSAEHLWV

OTOA

246

Q7RTW8
SSIDTVASLSWQTEW

OTOA

921

Q7RTW8
WWHVVLNLDTTIAIT

JMJD6

271

Q6NYC1
QGLTWTWSSLHNLDL

LRRTM4

246

Q86VH4
ALDWSWLQTEEEEHS

IKBKB

736

O14920
HPAVWDSVNWELSTT

EDRF1

956

Q3B7T1
EDSINWRHLSELLWS

HSP90AB4P

351

Q58FF6
KWLEHLNSSWITEDS

HERC1

11

Q15751
SWLHWDSQSHTLEGL

DAG1

106

Q14118
LIHESACWSDTLQRW

CANT1

281

Q8WVQ1
VSTVHLISSTDIWWN

PCNX4

501

Q63HM2
LISSTDIWWNRSLDT

PCNX4

506

Q63HM2
IALSNWWFVAHLTDL

NUP85

366

Q9BW27
AISSWDWLDISSVNS

POLG

341

P54098
VRWLSTHDPNITWST

PEG10

446

Q86TG7
GLSQHSVDQSWSWLD

LY75

1601

O60449
ETHWLSNLESTHWLE

MTMR2

376

Q13614
IQSLTLEWNSLGTWD

LRRC45

116

Q96CN5
KSHDQVWVLSWGTLE

FSTL5

551

Q8N475
WNADTDLVSWLSPHD

PQBP1

66

O60828
LWNEWCRTTDTTHLS

PSMG1

101

O95456
DWSLSDVDQWDTAAL

PIK3R2

156

O00459
AAHWTEGSVVSLTRW

FJX1

231

Q86VR8
EHTWLTEMLENWTRT

PLA2G4C

306

Q9UP65
HTWRSQNDTVTPDVW

FUCA2

371

Q9BTY2
STLHTVLWDGESRWT

GAK

1236

O14976
SEWSEARSWDTESVL

CSF2RB

426

P32927
MWELLTNESTNHSWD

COG1

386

Q8WTW3
QWASDLVSSIWSNAD

GIGYF2

1056

Q6Y7W6
WVGDISWTHDSLFLA

CPLANE1

316

Q9H799
ISIWFEVQRTWSHLE

DNAH17

1486

Q9UFH2
TLDWSENAVNGEHLW

DGKI

166

O75912
HKWSWTSRTETLLSL

C3orf20

461

Q8ND61
HSREWISQATAIWTA

CPA4

181

Q9UI42
THWSLSNSWDVDKGT

CPAMD8

1346

Q8IZJ3
DWIAFIHSNDIWISN

DPP8

226

Q6V1X1
EIGTWSDWSVAAHAT

CNTFR

286

P26992
VTDELWVFNIHSQSW

ATRNL1

381

Q5VV63
ASWEWRNSSLQSIDV

DNAH14

946

Q0VDD8
STWTVDHQLLWGEAL

GAA

736

P10253
EDSWTSLEHILWPFT

IRAG2

531

Q12912
SWDTKLIQWLHTTLV

KANSL3

186

Q9P2N6
WNDHVHILDTETFTW

KLHDC2

191

Q9Y2U9
VTNVRWSHDFQWVLS

EML6

566

Q6ZMW3
DTIWNELHSSNAARW

HDAC7

626

Q8WUI4
RWLSTSIPEAQWHSS

FASN

711

P49327
ESWLKNAWHFISESV

SACS

3241

Q9NZJ4
LVVLSWVSFWISLDS

GABRP

256

O00591
ESLRAWVAATWHEQE

FAN1

896

Q9Y2M0
WHEQEGRVASLVSWD

FAN1

906

Q9Y2M0
WERASASSWTLEDAT

ARHGAP20

1156

Q9P2F6
WHVSWSITANILAVS

SEC13

266

P55735
NAWAVTNHFSIWLAT

TAS2R20

86

P59543
DVSWTFTNHLSIWLA

TAS2R3

86

Q9NYW6
ILASQHAWAQLTFWE

TMEM205

71

Q6UW68
AVSAWLWSLTSETTL

TMEM191B

311

P0C7N4
HWTANSSKIITWLLE

SLC16A12

6

Q6ZSM3
FNEVSSWVTWLILTA

PLCE1

601

Q9P212
QILESLAWSHDSALW

RBL1

561

P28749
LAWSHDSALWEALQV

RBL1

566

P28749
RAELGSWSSQEHLEW

KIFC3

776

Q9BVG8
EWHSRWLEDNVTVEA

SIN3B

1101

O75182
ESLLSILHWSWTTLV

MYCBP2

1421

O75592
ILHWSWTTLVLGVEE

MYCBP2

1426

O75592
WHWATTQTTQLSLSF

MT-ND5

66

P03915
LTSTDIWALWHDAEN

NUP160

401

Q12769
WTSDWWTVHHSVEET

SUMF1

301

Q8NBK3
TSRKAWNEDHWEQTL

AATF

76

Q9NY61
WHVWTTLSQGSAATL

CHST5

96

Q9GZS9
VSDASWVSELLWSLF

AUP1

201

Q9Y679
GHWEWSCESLESLAV

ZNF135

131

P52742
VWVASEAWALSRHIT

TAS1R1

296

Q7RTX1
SEVHNWTLEDTLQWL

STIM2

131

Q9P246
ESSAWESVSSHDIWV

STYXL2

436

Q5VZP5
EQTWPSTHETLLTTW

SUSD4

306

Q5VX71
SEAVHWTWLCLQDIT

TMEM214

661

Q6NUQ4
RVLQLTSWDEDAWAS

VCL

246

P18206
RSDNTVTWLAAWTES

TOP1MT

241

Q969P6
CFVEHVSWWANSSLE

SERPINE3

126

A8MV23
IWHCESTLSSDWQIA

TMEM47

66

Q9BQJ4
DSSGWATILAVIWLH

VWA5A

721

O00534
AQGEWSEDLTAWTLS

TEK

621

Q02763
LVLLVDFAHSWNESW

SERINC3

176

Q13530
SHWSATRTLHEWLQQ

CAD

96

P27708
HVSWKLGWVEINSSS

TMEM241

51

Q24JQ0
CLATGSWDSTVHIWD

WDR38

161

Q5JTN6
WDHTIRVWDVESGSL

WDR12

276

Q9GZL7
THSLKTFHRNWDWES

TMTC3

416

Q6ZXV5
VAVDWESHINTKWSA

ZNF559

51

Q9BR84
WDLWSVHFTQISLDF

UHRF1BP1

691

Q6BDS2
TNDASLHVWDWVDLC

WDR73

361

Q6P4I2
SILLVATWVTHSSWL

XKR8

296

Q9H6D3
WWHATLNLDTSVFIS

JMJD8

246

Q96S16
VDWIHSNIYWTDSVL

LDLR

481

P01130
HALLRESWEAAQETW

ART5

61

Q96L15
DDIQDSWWSVLSILN

NAGA

216

P17050
SWWSVLSILNWFVEH

NAGA

221

P17050