Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	PYCR1 PYCR3	7.02e-05	3	91	2	1.10.3730.10
Domain	P5CR_dimer	PYCR1 PYCR3	7.02e-05	3	91	2	PF14748
Domain	P5CR_dimer	PYCR1 PYCR3	7.02e-05	3	91	2	IPR029036
Domain	P5CR	PYCR1 PYCR3	1.40e-04	4	91	2	PS00521
Domain	Pyrroline-COOH_reductase	PYCR1 PYCR3	1.40e-04	4	91	2	IPR000304
Domain	Leu-rich_rpt_typical-subtyp	IGSF10 LRFN4 PXDN CEP72 LRFN5 NRROS	2.28e-04	177	91	6	IPR003591
Domain	LRR_TYP	IGSF10 LRFN4 PXDN CEP72 LRFN5 NRROS	2.28e-04	177	91	6	SM00369
Domain	BRIX	PPAN IMP4	2.33e-04	5	91	2	PS50833
Domain	Brix	PPAN IMP4	2.33e-04	5	91	2	SM00879
Domain	Brix	PPAN IMP4	2.33e-04	5	91	2	IPR007109
Domain	Brix	PPAN IMP4	2.33e-04	5	91	2	PF04427
Domain	Leu-rich_rpt	IGSF10 LRFN4 PXDN CEP72 LRFN5 NRROS NLRP5	3.59e-04	271	91	7	IPR001611
Domain	ProC_N	PYCR1 PYCR3	4.85e-04	7	91	2	IPR028939
Domain	F420_oxidored	PYCR1 PYCR3	4.85e-04	7	91	2	PF03807
Domain	-	IGSF10 LRFN4 PXDN CEP72 LRFN5 NRROS NLRP5	9.78e-04	321	91	7	3.80.10.10
Domain	Cys-rich_flank_reg_C	IGSF10 LRFN4 PXDN LRFN5	9.79e-04	90	91	4	IPR000483
Domain	LRRCT	IGSF10 LRFN4 PXDN LRFN5	9.79e-04	90	91	4	SM00082
Domain	L_dom-like	IGSF10 LRFN4 PXDN CEP72 LRFN5 NRROS NLRP5	1.11e-03	328	91	7	IPR032675
Domain	LRRNT	IGSF10 LRFN4 PXDN LRFN5	1.34e-03	98	91	4	IPR000372
Domain	LRRNT	IGSF10 LRFN4 PXDN LRFN5	1.34e-03	98	91	4	SM00013
Domain	Ig_I-set	IGSF10 CILP2 LRFN4 PXDN LRFN5	2.37e-03	190	91	5	IPR013098
Domain	I-set	IGSF10 CILP2 LRFN4 PXDN LRFN5	2.37e-03	190	91	5	PF07679
Domain	6-PGluconate_DH_C-like	PYCR1 PYCR3	3.80e-03	19	91	2	IPR008927
Domain	LRR_1	LRFN4 PXDN CEP72 LRFN5 NRROS	4.35e-03	219	91	5	PF00560
Domain	UDPGT	UGT2A3 UGT3A1	4.64e-03	21	91	2	PF00201
Domain	UDPGT	UGT2A3 UGT3A1	4.64e-03	21	91	2	PS00375
Domain	UDP_glucos_trans	UGT2A3 UGT3A1	4.64e-03	21	91	2	IPR002213
Domain	IGc2	IGSF10 CILP2 LRFN4 PXDN LRFN5	5.85e-03	235	91	5	SM00408
Domain	Ig_sub2	IGSF10 CILP2 LRFN4 PXDN LRFN5	5.85e-03	235	91	5	IPR003598
Domain	-	PIK3C2G ITSN1 CAPN6 ASCC3	5.94e-03	148	91	4	2.60.40.150
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	CILP2 LRFN4 PXDN AMOT ANKRD28 FASTKD5 TTC17 ITGA2B NRROS HSD17B11 CTSA	8.58e-07	613	94	11	22268729
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	IGSF10 LRFN4 PXDN LRFN5	2.18e-06	34	94	4	18848646
Pubmed	Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen receptor alpha (ERalpha) involves multiple domains of both proteins.	ESR1 MED1	7.23e-06	2	94	2	15471764
Pubmed	New approach to capture and characterize synaptic proteome.	KIF5A KIF5C	7.23e-06	2	94	2	25352669
Pubmed	Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation.	ESR1 MED1	7.23e-06	2	94	2	20351249
Pubmed	Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor alpha.	HDAC4 ESR1	7.23e-06	2	94	2	16051668
Pubmed	Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH.	PYCR1 PYCR3	7.23e-06	2	94	2	2722838
Pubmed	Roles of Estrogen Receptor-α and the Coactivator MED1 During Human Endometrial Decidualization.	ESR1 MED1	7.23e-06	2	94	2	26849466
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	SLC12A6 TRPM4 IARS2 PPAN ATP7B AHNAK USP32 PYCR1 TTC17 STAM SLC39A10 HSD17B11	1.01e-05	952	94	12	38569033
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	ATP7B DISC1 ITSN1 USP32 HEATR5B VPS53 DMXL1	1.28e-05	285	94	7	34369648
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	IGSF10 PPP2R5A AMOT NOA1 DISC1 ANKRD28 STAM KDM6A SHC3 VPS13B	1.70e-05	686	94	10	29987050
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	PXDN AHNAK RICTOR TTC17 ASCC3 MED1	1.90e-05	202	94	6	33005030
Pubmed	Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.	KIF5A KIF5C	2.16e-05	3	94	2	17693257
Pubmed	Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.	KIF5A KIF5C	2.16e-05	3	94	2	7514426
Pubmed	HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1.	ESR1 MED1	2.16e-05	3	94	2	29187405
Pubmed	Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.	KIF5A KIF5C	2.16e-05	3	94	2	21768290
Pubmed	Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.	KIF5A KIF5C	2.16e-05	3	94	2	30068641
Pubmed	Functional specialization in proline biosynthesis of melanoma.	PYCR1 PYCR3	2.16e-05	3	94	2	23024808
Pubmed	Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis.	ESR1 NOTCH1	2.16e-05	3	94	2	18593928
Pubmed	Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.	ESR1 NOTCH1	2.16e-05	3	94	2	18593923
Pubmed	Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.	LRFN4 LRFN5	2.16e-05	3	94	2	20410109
Pubmed	[Involvement of Notch1 and ALK4/5 Signaling Pathways in Renal Tubular Cell Death: Their Application to Clarification of Cadmium Toxicity].	ACVR1B NOTCH1	2.16e-05	3	94	2	33342936
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PHKA1 PPP2R5A CEP72 AHNAK SYNE2 PYCR1 ANKRD28 RICTOR STAM SLC39A10 KDM6A NOTCH1	2.62e-05	1049	94	12	27880917
Pubmed	H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependency.	ESR1 KDM6A	4.32e-05	4	94	2	21841772
Pubmed	Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription.	ESR1 MED1	4.32e-05	4	94	2	10760302
Pubmed	Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.	TYMS ATP7B	4.32e-05	4	94	2	18593893
Pubmed	The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.	LRFN4 LRFN5	4.32e-05	4	94	2	21736948
Pubmed	Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites.	KIF5A KIF5C	4.32e-05	4	94	2	11986669
Pubmed	Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex.	ESR1 MED1	4.32e-05	4	94	2	10770935
Pubmed	KIF5C, a novel neuronal kinesin enriched in motor neurons.	KIF5A KIF5C	4.32e-05	4	94	2	10964943
Pubmed	MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia.	ESR1 ACVR1B NOTCH1	5.34e-05	27	94	3	20347265
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SLC12A6 ATP7B SYNE2 USP32 SLC39A10 HEATR5B VPS13B DMXL1	6.89e-05	504	94	8	34432599
Pubmed	Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.	ESR1 MED1	7.19e-05	5	94	2	17502350
Pubmed	UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.	KDM6A NOTCH1	7.19e-05	5	94	2	29073101
Pubmed	KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.	KIF5A KIF5C	7.19e-05	5	94	2	7528108
Pubmed	The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha.	ESR1 MED1	7.19e-05	5	94	2	15886699
Pubmed	Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.	ITSN1 KIF5A	7.19e-05	5	94	2	15256501
Pubmed	Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.	HDAC4 ESR1	7.19e-05	5	94	2	19893013
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	IARS2 NOA1 PYCR1 ANKRD28 FASTKD5 RICTOR KIF5C VPS53	8.00e-05	515	94	8	31617661
Pubmed	Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.	ESR1 AHNAK NOTCH1	8.14e-05	31	94	3	32546759
Pubmed	Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women.	LIPC ESR1	1.08e-04	6	94	2	19489872
Pubmed	Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.	ESR1 NOTCH1	1.08e-04	6	94	2	19838210
Pubmed	Chromosomal localization reveals three kinesin heavy chain genes in mouse.	KIF5A KIF5C	1.08e-04	6	94	2	9782088
Pubmed	Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.	RICTOR NOTCH1	1.08e-04	6	94	2	26437242
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	EPHX1 IARS2 NOA1 AHNAK PYCR1 FASTKD5 SLC39A10 HSD17B11 CTSA ALG1L2 PYCR3 CREB5 PCYOX1	1.43e-04	1451	94	13	30550785
Pubmed	Kinesin transports RNA: isolation and characterization of an RNA-transporting granule.	KIF5A KIF5C	1.50e-04	7	94	2	15312650
Pubmed	mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1.	KIF5A KIF5C	1.50e-04	7	94	2	20019668
Pubmed	Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia.	TYMS EPHX1	1.50e-04	7	94	2	19162321
Pubmed	Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins.	LRFN4 LRFN5	1.50e-04	7	94	2	16828986
Pubmed	Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.	KIF5A KIF5C	1.50e-04	7	94	2	21335237
Pubmed	PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.	ESR1 MED1	1.50e-04	7	94	2	16554032
Pubmed	Analysis of Kif5b expression during mouse kidney development.	KIF5A KIF5C	1.50e-04	7	94	2	25885434
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	GUCY1B2 HDAC4 DISC1 ESR1 ITSN1 SETBP1 NOTCH1	1.71e-04	430	94	7	35044719
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	IARS2 ITSN1 SYNE2 PYCR1 ANKRD28 FASTKD5 RICTOR TTC17 SLC39A10 ASCC3 PYCR3 VPS13B DMXL1	1.82e-04	1487	94	13	33957083
Pubmed	Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.	HDAC4 ESR1	2.00e-04	8	94	2	24413532
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	HDAC4 CEP72 AMOT ANKRD28 RICTOR STAM NOTCH1	2.13e-04	446	94	7	24255178
Pubmed	Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.	TYMS EPHX1 ESR1 KCNQ1	2.16e-04	108	94	4	19956635
Pubmed	Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.	TYMS EPHX1 ESR1	2.18e-04	43	94	3	18510611
Pubmed	Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms.	HDAC4 ESR1	2.57e-04	9	94	2	12535528
Pubmed	Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.	KIF5A KIF5C	2.57e-04	9	94	2	9624122
Pubmed	Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.	HDAC4 NOTCH1	2.57e-04	9	94	2	24684754
Pubmed	Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.	ESR1 MED1	3.21e-04	10	94	2	12738788
Pubmed	Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.	KIF5A KIF5C	3.21e-04	10	94	2	21976701
Pubmed	The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.	ESR1 MED1	3.21e-04	10	94	2	9653119
Pubmed	Enhancer activation requires trans-recruitment of a mega transcription factor complex.	ESR1 MED1	3.21e-04	10	94	2	25303530
Pubmed	Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5.	ITGA2B NOTCH1	3.21e-04	10	94	2	37669937
Pubmed	Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.	ITSN1 NOTCH1	3.21e-04	10	94	2	16798735
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	AHNAK ITSN1 USP32 STAM ASCC3 HSD17B11 PYCR3	3.37e-04	481	94	7	28190767
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CEP72 AMOT SETBP1 SYNE2 ANKRD28	3.73e-04	225	94	5	12168954
Pubmed	A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.	TYMS ESR1	3.91e-04	11	94	2	18285546
Pubmed	Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition.	ITGA2B NOTCH1	3.91e-04	11	94	2	26204127
Pubmed	Claudin-4 localization in epithelial ovarian cancer.	AHNAK SLC39A10 NOTCH1	4.29e-04	54	94	3	36237976
Pubmed	MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling.	ESR1 MED1	4.69e-04	12	94	2	18391015
Pubmed	Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.	NEURL1 CTSA	4.69e-04	12	94	2	14960280
Pubmed	The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.	KIF5A KIF5C	4.69e-04	12	94	2	15834408
Pubmed	The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.	KIF5A KIF5C	4.69e-04	12	94	2	16018997
Pubmed	Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.	KIF5A KIF5C	4.69e-04	12	94	2	16301330
Pubmed	Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.	HDAC4 SETBP1	5.53e-04	13	94	2	22693459
Pubmed	Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.	ESR1 MED1	5.53e-04	13	94	2	11266503
Pubmed	MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.	UGT2A3 RICTOR ACVR1B NOTCH1	5.79e-04	140	94	4	20819778
Pubmed	Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.	TYMS EPHX1 LIPC ESR1	5.95e-04	141	94	4	18636124
Pubmed	MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.	ESR1 MED1	6.44e-04	14	94	2	17641689
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PLK2 ITSN1 ZNF197 USP32 NFKBID TTC17 KIF5A KIF5C STAM IDS KDM6A	7.01e-04	1285	94	11	35914814
Pubmed	Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.	HDAC4 NEURL1 KIF5C	7.40e-04	65	94	3	23453885
Pubmed	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	NEURL1 KCNQ1	7.42e-04	15	94	2	20526338
Pubmed	Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples.	EPHX1 ESR1	7.42e-04	15	94	2	15654505
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	CILP2 LIPC ACSM1	7.73e-04	66	94	3	20679960
Pubmed	Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.	DISC1 ESR1	8.46e-04	16	94	2	19693267
Pubmed	Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women.	EPHX1 ESR1	8.46e-04	16	94	2	19415745
Pubmed	A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.	SLC12A6 KIF5A	9.57e-04	17	94	2	20808911
Pubmed	Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.	ZNF407 ZNF236	9.57e-04	17	94	2	19690890
Pubmed	Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes.	SLC12A6 KCNQ1	9.57e-04	17	94	2	18353863
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	IGSF10 LRFN4 PXDN LRFN5	9.99e-04	162	94	4	25826454
Pubmed	Characterization of immunoisolated human gastric parietal cells tubulovesicles: identification of regulators of apical recycling.	EPHX1 AHNAK KCNQ1	1.08e-03	74	94	3	17255364
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	AMOT NOA1 DISC1 KIF5A KIF5C MED1 HEATR5B CTSA PYCR3 NLRP5	1.12e-03	1153	94	10	29845934
Pubmed	Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.	EPHX1 LIPC MED1	1.17e-03	76	94	3	22323595
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	CEP72 ITSN1 STAM ASCC3	1.17e-03	169	94	4	31462741
Pubmed	Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling.	ESR1 NOTCH1	1.20e-03	19	94	2	29885287
Pubmed	A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.	CILP2 LIPC	1.20e-03	19	94	2	19656773
Pubmed	Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.	ESR1 MED1	1.20e-03	19	94	2	17392787
Interaction	FBXO2 interactions	CILP2 LRFN4 PXDN AMOT SYNE2 TTC17 KLK5 NOTCH1 RNF157 PCYOX1	1.65e-05	411	91	10	int:FBXO2
Interaction	FBXO6 interactions	CILP2 LRFN4 PXDN AMOT ANKRD28 FASTKD5 TTC17 ITGA2B NRROS NUDT9 HSD17B11 CTSA PCYOX1	1.95e-05	717	91	13	int:FBXO6
Interaction	BAG2 interactions	VWA5B2 SLC12A6 HDAC4 AMOT DISC1 AHNAK RICTOR STAM ASCC3 KDM6A VPS13B NLRP5	2.29e-05	622	91	12	int:BAG2
Cytoband	1q42.1	EPHX1 DISC1	2.70e-04	12	94	2	1q42.1
Cytoband	4q22.1	NUDT9 HSD17B11	1.31e-03	26	94	2	4q22.1
Coexpression	CUI_TCF21_TARGETS_2_UP	TYMS TRPM4 PPAN LRFN4 ESR1 SYNE2 CAPN6 NEURL1 PYCR1 PYCR3	3.89e-06	437	94	10	M1610
Coexpression	LEE_NEURAL_CREST_STEM_CELL_DN	PLK2 SYNE2 CAPN6 ZNF236 CREB5 NOTCH1	5.24e-06	122	94	6	M10276
Coexpression	CUI_TCF21_TARGETS_2_UP	TYMS TRPM4 PPAN LRFN4 ESR1 SYNE2 CAPN6 NEURL1 PYCR1 PYCR3	5.54e-06	455	94	10	MM1189
Coexpression	LEIN_CEREBELLUM_MARKERS	PHKA1 IL16 CEP72 AMOT SYNE2	1.39e-05	85	94	5	MM720
Coexpression	LEIN_CEREBELLUM_MARKERS	PHKA1 IL16 CEP72 AMOT SYNE2	1.39e-05	85	94	5	M1723
Coexpression	CAIRO_LIVER_DEVELOPMENT_UP	PLK2 LRFN4 PXDN SYNE2 CAPN6 PDZD2	3.03e-05	166	94	6	M17163
Coexpression	CAIRO_LIVER_DEVELOPMENT_UP	PLK2 LRFN4 PXDN SYNE2 CAPN6 PDZD2	3.13e-05	167	94	6	MM1057
Coexpression	MURARO_PANCREAS_DELTA_CELL	LRFN5 SETBP1 SYNE2 ACVR1B NUDT9 IDS EDN3	3.34e-05	250	94	7	M39170
Coexpression	GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP	NOA1 STAM HSD17B11 VPS53 PCYOX1 PDZD2	7.85e-05	197	94	6	M9862
Coexpression	GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP	VWA5B2 USP32 STAM ASCC3 NOTCH1 RNF157	8.30e-05	199	94	6	M9759
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP	PPP2R5A NOA1 RICTOR STAM VPS53 VPS13B	8.54e-05	200	94	6	M8497
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PHKA1 USP32 ZNF407 ITGA2B NRROS VPS13B	1.76e-06	172	94	6	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17\|lymph-node_spleen / Manually curated celltypes from each tissue	AHNAK SYNE2 TAS1R2 ANKRD28 KIF5C IDS	2.95e-06	188	94	6	a20521198c6db17589535fb439533329582c9dd2
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Memory_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	AHNAK NFKBID ANKRD28 IDS CTSA NOTCH1	3.33e-06	192	94	6	37d0d0fdd6bc3114d546020b472b6df9392392f4
ToppCell	erythropoietic-CD34+_Pro-erythroblast\|World / Lineage and Cell class	TYMS IGSF10 PYCR1 ANKRD28 ITGA2B FAM124B	3.53e-06	194	94	6	cd12d01f6f2f12bbc33ed523bc678d3965074974
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-9\|TCGA-Kidney / Sample_Type by Project: Shred V9	TOMM40L PIK3C2G KCNQ1 KIF5A SHC3	8.97e-06	132	94	5	f1ef63a4842ab6ca584a9dcc2dd5b2108fc990aa
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp-Inhibitory_Gad1Gad2_Htr3a.Ibsp_(Interneuron,__(candidate_CGE-derived_7))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SP8 DPYS ENPP7 NLRP5	1.03e-05	64	94	4	c13a7edad4d52a955e2c2247139246522d9e4463
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp-Inhibitory_Gad1Gad2_Htr3a.Ibsp_(Interneuron,__(candidate_CGE-derived_7))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SP8 DPYS ENPP7 NLRP5	1.03e-05	64	94	4	eefb4573ec4ff8efe602543ccbe555dbef1c4d54
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SP8 DPYS ENPP7 NLRP5	1.03e-05	64	94	4	fcc0f3fa0b462620d031aae810a01fadb7c01202
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	IGSF10 ATP7B PYCR1 ITGA2B FAM124B	3.12e-05	171	94	5	3ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCell	wk_15-18-Hematologic-Myeloid-Eosinophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ANKRD28 ITGA2B STAM NRROS TAS2R46	3.30e-05	173	94	5	a85cead231e03945fabbc7762540ad21fe4299df
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IGSF10 DPYS IL16 LRFN5 SETBP1	4.10e-05	181	94	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYMS CEP72 ANKRD28 KIF5A NOTCH1	4.20e-05	182	94	5	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega-Mega-Mast\|blood / Manually curated celltypes from each tissue	TYMS IGSF10 NEURL1 PYCR1 ITGA2B	4.20e-05	182	94	5	1923b5669901f828e890416c22d1f1d21a4a2c6a
ToppCell	mild-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SLC12A6 USP32 RICTOR CREB5 NOTCH1	4.43e-05	184	94	5	1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	AHNAK SYNE2 ANKRD28 KIF5C IDS	4.78e-05	187	94	5	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	IL16 LRFN5 ESR1 SETBP1 CREB5	4.91e-05	188	94	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 PLK2 AHNAK IDS HSD17B11	5.16e-05	190	94	5	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	control-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SLC12A6 USP32 RICTOR CREB5 NOTCH1	5.29e-05	191	94	5	db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	DISC1 AOAH NFKBID CREB5 ZNF710	5.29e-05	191	94	5	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	TYMS ATP7B PYCR1 ITGA2B FAM124B	5.42e-05	192	94	5	cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	HDAC4 AHNAK SYNE2 IDS KDM6A	5.42e-05	192	94	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IGSF10 IL16 LRFN5 ESR1 SETBP1	5.56e-05	193	94	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL16 AHNAK SETBP1 NFKBID IDS	5.69e-05	194	94	5	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	HDAC4 AHNAK SYNE2 TTC17 ASCC3	5.83e-05	195	94	5	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	CV-Mild-0\|Mild / Virus stimulation, Condition and Cluster	IL16 AHNAK AOAH IDS HSD17B11	5.83e-05	195	94	5	2ffb9a9b6143bb404fe454cd939b573252bba6e9
ToppCell	mLN-T_cell-Th17\|T_cell / Region, Cell class and subclass	AHNAK NFKBID ANKRD28 KIF5C PDZD2	6.27e-05	198	94	5	efdc9515dd9fb20ef9c8ddc106d88cbdde7d6ea2
ToppCell	(1)_T_cell-(12)_Th1\|(1)_T_cell / shred on Cell_type and subtype	AHNAK SYNE2 NFKBID ANKRD28 IDS	6.42e-05	199	94	5	15133e0a4ea6cfcc27c1d438d9e854879ea84c30
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLK2 SYNE2 ZNF518B FAM124B NOTCH1	6.58e-05	200	94	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A SYNE2 ZNF518B FAM124B	6.58e-05	200	94	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PPP2R5A AHNAK ZNF518B NRROS FAM124B	6.58e-05	200	94	5	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLK2 PPP2R5A ZNF518B NRROS FAM124B	6.58e-05	200	94	5	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATP7B GUCY1B2 CAPN6 PYCR1	8.71e-05	110	94	4	b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATP7B GUCY1B2 CAPN6 PYCR1	8.71e-05	110	94	4	ee45592e936d32881c0f3429c21360670e5b3ce3
Drug	Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	SLC9A5 ATP7B DISC1 ESR1 NEURL1 VPS53 VPS13B	1.39e-05	194	92	7	2844_UP
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	TRPM4 DISC1 NEURL1 ACVR1B ZNF236 VPS53 ZNF710	1.54e-05	197	92	7	7351_UP
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; HL60; HT_HG-U133A	PLK2 LRFN4 ATP7B PIK3C2G AMOT SETBP1 KCNQ1	1.59e-05	198	92	7	2536_UP
Drug	Lymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A	AMOT ESR1 ACSM1 HSD17B11 KDM6A VPS53 VPS13B	1.64e-05	199	92	7	5994_UP
Drug	Torsemide [56211-40-6]; Up 200; 11.4uM; HL60; HT_HG-U133A	LRFN4 ESR1 KLK5 ACVR1B IDS VPS53 ZNF710	1.64e-05	199	92	7	2956_UP
Drug	Levodopa [59-92-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A	SLC12A6 HDAC4 ESR1 ITSN1 ACVR1B KDM6A ZNF710	1.64e-05	199	92	7	1472_DN
Drug	Proxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A	TRPM4 SETBP1 ACVR1B IDS VPS53 CREB5 NOTCH1	1.64e-05	199	92	7	7290_UP
Disease	spinal muscular atrophy (implicated_via_orthology)	ATP7B KIF5A KIF5C	2.27e-06	9	90	3	DOID:12377 (implicated_via_orthology)
Disease	level of ADP-ribose pyrophosphatase, mitochondrial in blood serum	NUDT9 HSD17B11	9.20e-06	2	90	2	OBA_2042674
Disease	hepatitis (implicated_via_orthology)	LIPC ATP7B	2.75e-05	3	90	2	DOID:2237 (implicated_via_orthology)
Disease	S-1-pyrroline-5-carboxylate measurement	TAS1R2 PYCR3	5.50e-05	4	90	2	EFO_0800136
Disease	ADP-ribose pyrophosphatase, mitochondrial measurement	NUDT9 HSD17B11	5.50e-05	4	90	2	EFO_0801349
Disease	lung small cell carcinoma (is_implicated_in)	RICTOR ACVR1B KDM6A	8.51e-05	28	90	3	DOID:5409 (is_implicated_in)
Disease	Prostatic Neoplasms	TYMS EPHX1 TRPM4 IL16 ATP7B ESR1 ITSN1 KLK5 KDM6A	1.12e-04	616	90	9	C0033578
Disease	Malignant neoplasm of prostate	TYMS EPHX1 TRPM4 IL16 ATP7B ESR1 ITSN1 KLK5 KDM6A	1.12e-04	616	90	9	C0376358
Disease	SPARC-like protein 1 measurement	NUDT9 HSD17B11	1.37e-04	6	90	2	EFO_0008289
Disease	Lung Neoplasms	TYMS EPHX1 ESR1 ACSM1 RICTOR IDS	1.64e-04	265	90	6	C0024121
Disease	Malignant neoplasm of lung	TYMS EPHX1 ESR1 ACSM1 RICTOR IDS	1.68e-04	266	90	6	C0242379
Disease	hair color	IL16 HDAC4 AHNAK SYNE2 CREB5 EDN3	3.87e-04	311	90	6	EFO_0003924
Disease	Intellectual Disability	HDAC4 DISC1 SETBP1 PYCR1 KIF5A ASCC3 VPS53	4.43e-04	447	90	7	C3714756
Disease	fetal genotype effect measurement, body weights and measures	DISC1 ESR1 KCNQ1	4.57e-04	49	90	3	EFO_0004324, EFO_0007959
Disease	X-18913 measurement	SP8 ANKRD28	4.97e-04	11	90	2	EFO_0800795
Disease	hair colour measurement	IL16 PXDN HDAC4 AHNAK SETBP1 SYNE2 CREB5 EDN3	5.89e-04	615	90	8	EFO_0007822
Disease	motor neuron disease (implicated_via_orthology)	KIF5A KIF5C	5.95e-04	12	90	2	DOID:231 (implicated_via_orthology)
Disease	lymphangioleiomyomatosis (is_marker_for)	ESR1 RICTOR	5.95e-04	12	90	2	DOID:3319 (is_marker_for)
Disease	acute lymphoblastic leukemia (is_implicated_in)	TYMS EPHX1 KDM6A	6.42e-04	55	90	3	DOID:9952 (is_implicated_in)
Disease	hypothyroidism (implicated_via_orthology)	PHKA1 LIPC	7.02e-04	13	90	2	DOID:1459 (implicated_via_orthology)
Disease	Profound Mental Retardation	HDAC4 DISC1 SETBP1 ASCC3	8.81e-04	139	90	4	C0020796
Disease	Mental Retardation, Psychosocial	HDAC4 DISC1 SETBP1 ASCC3	8.81e-04	139	90	4	C0025363
Disease	Mental deficiency	HDAC4 DISC1 SETBP1 ASCC3	8.81e-04	139	90	4	C0917816
Disease	Bladder Neoplasm	HDAC4 ESR1 KDM6A NOTCH1	9.04e-04	140	90	4	C0005695
Disease	Malignant neoplasm of urinary bladder	HDAC4 ESR1 KDM6A NOTCH1	9.29e-04	141	90	4	C0005684
Disease	Neoplasm of uncertain or unknown behavior of bladder	KDM6A NOTCH1	9.41e-04	15	90	2	C0496930
Disease	Benign neoplasm of bladder	KDM6A NOTCH1	9.41e-04	15	90	2	C0154017
Disease	Carcinoma in situ of bladder	KDM6A NOTCH1	9.41e-04	15	90	2	C0154091
Disease	amyotrophic lateral sclerosis	LIPC DISC1 KIF5A CREB5	1.03e-03	145	90	4	MONDO_0004976
Disease	anthranilic acid measurement	HDAC4 KCNQ1	1.07e-03	16	90	2	EFO_0010460
Disease	level of Sphingomyelin (d32:1) in blood serum	LIPC SYNE2	1.21e-03	17	90	2	OBA_2045173
Disease	unipolar depression, bipolar disorder	LRFN5 SETBP1 SYNE2 ASCC3	1.35e-03	156	90	4	EFO_0003761, MONDO_0004985
Disease	Carcinoma of bladder	KDM6A NOTCH1	1.36e-03	18	90	2	C0699885
Disease	Colorectal Carcinoma	TYMS ATP7B TOMM40L SETBP1 CAPN6 NEURL1 STAM KDM6A	1.38e-03	702	90	8	C0009402
Disease	Carcinomatosis	EPHX1 PLK2 ATP7B ESR1	1.59e-03	163	90	4	C0205699
Disease	Carcinoma, Spindle-Cell	EPHX1 PLK2 ATP7B ESR1	1.59e-03	163	90	4	C0205697
Disease	Undifferentiated carcinoma	EPHX1 PLK2 ATP7B ESR1	1.59e-03	163	90	4	C0205698
Disease	Anaplastic carcinoma	EPHX1 PLK2 ATP7B ESR1	1.59e-03	163	90	4	C0205696
Disease	Carcinoma	EPHX1 PLK2 ATP7B ESR1	1.62e-03	164	90	4	C0007097
Disease	Lymphoma, Diffuse	TYMS EPHX1	1.86e-03	21	90	2	C3714542
Disease	Low Grade Lymphoma (neoplasm)	TYMS EPHX1	1.86e-03	21	90	2	C0079747
Disease	Lymphoma, Intermediate-Grade	TYMS EPHX1	1.86e-03	21	90	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	TYMS EPHX1	1.86e-03	21	90	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	TYMS EPHX1	1.86e-03	21	90	2	C0079757
Disease	Lymphoma, Undifferentiated	TYMS EPHX1	1.86e-03	21	90	2	C0024306
Disease	Reticulosarcoma	TYMS EPHX1	1.86e-03	21	90	2	C0024302
Disease	Lymphoma, Mixed-Cell	TYMS EPHX1	1.86e-03	21	90	2	C0024304
Disease	progranulin measurement	LRFN5 ITGA2B	2.04e-03	22	90	2	EFO_0004625
Disease	Lymphoma, Non-Hodgkin, Familial	TYMS EPHX1	2.04e-03	22	90	2	C4721532
Disease	Lymphoma, Small Noncleaved-Cell	TYMS EPHX1	2.04e-03	22	90	2	C0079770
Disease	QRS duration	SP8 SETBP1 KCNQ1 ANKRD28 HEATR5B	2.22e-03	298	90	5	EFO_0005055
Disease	phosphatidylserines measurement	LIPC ASCC3	2.23e-03	23	90	2	EFO_0020049
Disease	alcohol dependence	HDAC4 LRFN5 ESR1 FAM124B	2.42e-03	183	90	4	MONDO_0007079
Disease	Cerebral Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0750935
Disease	Intracranial Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0750936
Disease	Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0004114
Disease	Grade I Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0205768
Disease	Mixed oligoastrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0547065
Disease	inflammatory bowel disease (implicated_via_orthology)	IL16 PDZD2	2.64e-03	25	90	2	DOID:0050589 (implicated_via_orthology)
Disease	Pilocytic Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0334583
Disease	Juvenile Pilocytic Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0280783
Disease	Diffuse Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0280785
Disease	Childhood Cerebral Astrocytoma	ESR1 NOTCH1	2.64e-03	25	90	2	C0338070
Disease	Gemistocytic astrocytoma	ESR1 NOTCH1	2.85e-03	26	90	2	C0334581
Disease	Protoplasmic astrocytoma	ESR1 NOTCH1	2.85e-03	26	90	2	C0334580
Disease	Fibrillary Astrocytoma	ESR1 NOTCH1	2.85e-03	26	90	2	C0334582

Protein segments in the cluster

Peptide	Gene	Start	Entry
QGPLPNQHSLKGMEH	AMOT	221	Q4VCS5
LQHRLFMKLGSTHSP	ALG1L2	26	C9J202
AQAHGHMKPLTASQV	ATP7B	1386	P35670
KLALSAASGLAHLHM	ACVR1B	306	P36896
AHLHMEIVGTQGKPG	ACVR1B	316	P36896
GKTPLHMTALHGRFS	ANKRD28	306	O15084
TQLLNTMGHHTVGLK	AHNAK	71	Q09666
EKITHLGHSLMSLTG	CEP72	41	Q9P209
LPAMTKNNHGHIVTV	HSD17B11	156	Q8NBQ5
TANITAGHLLMHLIG	MT-ATP6	161	P00846
AGHLLMHLIGSATLA	MT-ATP6	166	P00846
LAVGLSHGDHSSMKL	BBS12	271	Q6ZW61
PALLEAKMHAISGNH	DISC1	586	Q9NRI5
GHLLHSSLPGLSRME	DMXL1	1491	Q9Y485
LGTMSEAKPHLITHG	IMP4	176	Q96G21
LVKHMKNIHLPDGSA	PIK3C2G	1346	O75747
LGAAKMLLHSEQHPG	PYCR1	211	P32322
NMIDNIPKGTFSHLH	LRFN5	181	Q96NI6
VMQTLKHLNSHLPNG	AOAH	396	P28039
LKAALTHHPAAMSNG	CREB5	236	Q02930
DMLHQLLSLHGGSTP	KCNQ1	611	P51787
SLQHGMVGPLHSSLA	NOTCH1	2341	P46531
GGAAHSPLLQHMVLL	HDAC4	406	P56524
KAHGNTALHMAAALP	NFKBID	241	Q8NI38
TLKHPAHHGMGKNLA	KIAA0087	86	Q14695
AHHGMGKNLATSLPT	KIAA0087	91	Q14695
PSAMKNLLHHILSGK	PHKA1	951	P46020
HLGHNTMVTKPCGAL	KIAA1109	4716	Q2LD37
GKLVLPGGIDTHTHM	DPYS	56	Q14117
GNLLSHVGHTILGMN	KDM6A	1116	O15550
EAGGSVIHPLNLHMK	PCYOX1	86	Q9UHG3
HTKASGMALLHQIQG	ESR1	6	P03372
DSSGNKIMHPVSGKH	NUDT9	181	Q9BW91
GNHSKALEMTGIHAP	PDZD2	1356	O15018
IKNLFSPIMSENHGH	IL16	721	Q14005
EHMGLSVGIKQPIGH	LIPC	226	P11150
SHPGHSNDLMLIKLN	KLK5	146	Q9Y337
MLGTHPHLRQLDLGS	NLRP5	776	P59047
LFIGTLSCHPHGVKM	RICTOR	661	Q6R327
HIAFLTIKGAGHMVP	CTSA	446	P10619
GPLAMTVHLLANSGH	FAM124B	6	Q9H5Z6
KAFVILGIPHSHSML	FASTKD5	211	Q7L8L6
LMLHSNGIHTIPDKT	IGSF10	86	Q6WRI0
SHVKGLHLNMALVLS	EPHX1	241	P07099
IPSVMKAHGAHLKAS	HEATR5B	651	Q9P2D3
MQGQGALKESHIHLP	C18orf15	1	Q96N68
QALDLHHPKLMPGSG	EDN3	206	P14138
SHDKTMSGHLTGPQA	ITSN1	231	Q15811
GKTHTMEGKLHDPQL	KIF5A	91	Q12840
MSVGKVFHPGISSNH	IDS	131	P22304
ANDGHLATLLPMLHT	ENPP7	401	Q6UWV6
HQLTQGRLGHKPMVS	CAPN6	71	Q9Y6Q1
HLIQSCGLGGMKHNT	SLC12A6	841	Q9UHW9
MSGDALLHLLPHSQG	SLC39A10	451	Q9ULF5
SVHHGAPLQLLKSMG	RXYLT1	366	Q9Y2B1
HAGHTLLQIPMGGKE	NOA1	581	Q8NC60
LSNLHKMGAPEAGLA	FTH1P19	116	P0C7X4
LMEHHSGSQGPLLTT	MED1	946	Q15648
GFLRKMPSLSHLNLH	NRROS	346	Q86YC3
LHGKGSQDPSMKVHI	TAS2R46	211	P59540
LHVLGDGHLSGMLPS	RNF157	386	Q96PX1
LLQGHMRSHTGEKPF	SCRT2	226	Q9NQ03
GSDLPLHKMAIQGFH	SYNE2	1236	Q8WXH0
GKTHTMEGKLHDPQL	KIF5C	91	O60282
SRMESHGLPNKVHLS	GUCY1B2	516	O75343
FVLTGMHNGQAKHLL	SHC3	531	Q92529
QPLMGHKDHTHLSPG	SLC9A5	866	Q14940
HVTMAKGTGLVHTAP	IARS2	381	Q9NSE4
LDLGGKHSPICHTTM	ITGA2B	566	P08514
HIPAFTMGIKHSLHL	ODF3L1	251	Q8IXM7
TAKMLLHEGQHPAQL	PYCR3	216	Q53H96
GASSHLLSPAGQHLM	SP8	266	Q8IXZ3
LIPMHTAKGLALFHA	PPP2R5A	276	Q15172
GFPKMAKHSHGLALQ	ACSM1	231	Q08AH1
SNLKLTLAFGIGMHH	ASCC3	1606	Q8N3C0
AASQIHMPGHVEALK	CILP2	666	Q8IUL8
HNVTMLHQSGKFLIP	UGT3A1	51	Q6NUS8
SSLLMHLRNHSGEKP	ZNF197	411	O14709
HPHTKGSQILMDLSH	NEURL1	66	O76050
LVLNSFGPHGMHVKL	PPAN	141	Q9NQ55
THLVPGTFNHLESMK	PXDN	171	Q92626
GGVAGHDLNSLKHMP	ZBED8	56	Q8IZ13
NLLGHMHLHAGSKPF	ZNF710	561	Q8N1W2
GFLNKHAMTVHPTDL	ZNF654	761	Q8IZM8
MIAHITGLKPGDFIH	TYMS	236	P04818
HKDPHVAMQALTLLG	STAM	56	Q92783
GNLPTSMHTLDHLHG	TTC17	951	Q96AE7
ITTLNHLHMLAGGVD	VPS53	146	Q5VIR6
GGLFSLHANMKGIVH	TAS1R2	36	Q8TE23
HQPHLMLEGGSLSSA	VWA5B2	276	Q8N398
KLSEGLMDGSPHFLH	VPS13B	1476	Q7Z7G8
GHSTHLSGGKQVLPM	VPS13B	3556	Q7Z7G8
QVAHTIHMSALGLPG	TOMM40L	61	Q969M1
LGHPKTKAFITHGGM	UGT2A3	361	Q6UWM9
GSLKVHMRLHTGAKP	ZNF236	1236	Q9UL36
LKEHMQTHQAGPSLS	ZNF236	1701	Q9UL36
NGAHMSLLPDKKTVH	PLK2	531	Q9NYY3
LSGLNVHIAMKHPTK	ZNF407	1426	Q9C0G0
AKHGVHLQGPVSMGL	SETBP1	1111	Q9Y6X0
SHGLSLGHFLTPMRL	TRPM4	446	Q8TD43
GILNAHDTTKMGHLT	USP32	321	Q8NFA0
THLNGGHNSLTMSPK	ZNF518B	11	Q9C0D4
GAMPALHTLNLDHNL	LRFN4	166	Q6PJG9