Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	2.43e-06	5	126	3	GO:0030156
GeneOntologyMolecularFunction	nitric-oxide synthase activity	NOS2 NOS3	1.18e-04	3	126	2	GO:0004517
GeneOntologyMolecularFunction	carbohydrate binding	CLEC18A CLEC18C PKD1L2 ITIH1 LMAN1L PRG2 AGL SIGLEC10 SIGLEC1	1.57e-04	310	126	9	GO:0030246
GeneOntologyMolecularFunction	extracellular matrix structural constituent	CILP LAMA5 SSPOP TINAGL1 PRG2 MUC2 MUC5AC	1.93e-04	188	126	7	GO:0005201
GeneOntologyMolecularFunction	tetrahydrobiopterin binding	NOS2 NOS3	2.35e-04	4	126	2	GO:0034617
GeneOntologyCellularComponent	extracellular matrix	SEMA7A CILP LAMA5 SSPOP TF F12 ITIH1 TINAGL1 LMAN1L CELA3B SSC5D CELA3A FCGBP PRG2 ADAMTS14 MUC2 MUC5AC OTOG	7.24e-08	656	125	18	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	SEMA7A CILP LAMA5 SSPOP TF F12 ITIH1 TINAGL1 LMAN1L CELA3B SSC5D CELA3A FCGBP PRG2 ADAMTS14 MUC2 MUC5AC OTOG	7.58e-08	658	125	18	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	SEMA7A CILP LAMA5 SSPOP TF F12 ITIH1 TINAGL1 LMAN1L CELA3B SSC5D CELA3A PRG2 MUC2	3.56e-06	530	125	14	GO:0062023
GeneOntologyCellularComponent	mucus layer	MUC2 MUC5AC	1.06e-04	3	125	2	GO:0070701
GeneOntologyCellularComponent	cell pole	TF PKP2 ASTN2	2.21e-04	20	125	3	GO:0060187
GeneOntologyCellularComponent	THO complex	THOC3 THOC6	5.24e-04	6	125	2	GO:0000347
GeneOntologyCellularComponent	THO complex part of transcription export complex	THOC3 THOC6	5.24e-04	6	125	2	GO:0000445
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	6.13e-04	28	125	3	GO:0002177
Domain	EGF_3	TPO CLEC18A CLEC18C SSPOP F12 MALRD1 TENM4 CELSR3 TIE1 ASTN2 ADAM33 OTOG PEAR1	6.91e-09	235	126	13	PS50026
Domain	C8	SSPOP FCGBP MUC2 MUC5AC OTOG	9.84e-09	12	126	5	PF08742
Domain	TIL	SSPOP FCGBP MUC2 MUC5AC OTOG	9.84e-09	12	126	5	PF01826
Domain	EGF-like_dom	TPO CLEC18A LAMA5 CLEC18C F12 FCGBP MALRD1 TENM4 CELSR3 TIE1 ADAM33 OTOG PEAR1	1.38e-08	249	126	13	IPR000742
Domain	Unchr_dom_Cys-rich	SSPOP FCGBP MUC2 MUC5AC OTOG	1.59e-08	13	126	5	IPR014853
Domain	C8	SSPOP FCGBP MUC2 MUC5AC OTOG	1.59e-08	13	126	5	SM00832
Domain	EGF_1	TPO CLEC18A LAMA5 CLEC18C SSPOP F12 MALRD1 TENM4 CELSR3 TIE1 ASTN2 ADAM33 PEAR1	1.83e-08	255	126	13	PS00022
Domain	TIL_dom	SSPOP FCGBP MUC2 MUC5AC OTOG	2.46e-08	14	126	5	IPR002919
Domain	EGF_2	TPO CLEC18A LAMA5 CLEC18C SSPOP F12 MALRD1 TENM4 CELSR3 TIE1 ASTN2 ADAM33 PEAR1	2.89e-08	265	126	13	PS01186
Domain	VWF_type-D	SSPOP FCGBP MUC2 MUC5AC OTOG	5.31e-08	16	126	5	IPR001846
Domain	VWFD	SSPOP FCGBP MUC2 MUC5AC OTOG	5.31e-08	16	126	5	PS51233
Domain	VWD	SSPOP FCGBP MUC2 MUC5AC OTOG	5.31e-08	16	126	5	SM00216
Domain	VWD	SSPOP FCGBP MUC2 MUC5AC OTOG	5.31e-08	16	126	5	PF00094
Domain	EGF	TPO CLEC18A LAMA5 CLEC18C F12 FCGBP MALRD1 TENM4 CELSR3 TIE1 ADAM33 PEAR1	6.54e-08	235	126	12	SM00181
Domain	VWC_out	SSPOP FCGBP MUC2 MUC5AC OTOG	1.39e-07	19	126	5	SM00215
Domain	EGF-like_CS	TPO CLEC18A LAMA5 CLEC18C F12 MALRD1 TENM4 CELSR3 TIE1 ADAM33 PEAR1	1.58e-06	261	126	11	IPR013032
Domain	WxxW_domain	CILP MUC2 MUC5AC	5.91e-06	6	126	3	IPR025155
Domain	Mucin2_WxxW	CILP MUC2 MUC5AC	5.91e-06	6	126	3	PF13330
Domain	VWF_dom	SSPOP FCGBP MUC2 MUC5AC OTOG	8.99e-06	42	126	5	IPR001007
Domain	Cys_knot_C	SSPOP MUC2 MUC5AC OTOG	2.24e-05	25	126	4	IPR006207
Domain	CTCK_2	SSPOP MUC2 MUC5AC OTOG	2.24e-05	25	126	4	PS01225
Domain	M_domain	TNRC6C TNRC6A	4.52e-05	2	126	2	PF12938
Domain	GW182_M_dom	TNRC6C TNRC6A	4.52e-05	2	126	2	IPR026805
Domain	VWC	SSPOP FCGBP MUC2 MUC5AC	1.22e-04	38	126	4	SM00214
Domain	CAP	CLEC18A CLEC18C GLIPR2	1.29e-04	15	126	3	PF00188
Domain	SCP	CLEC18A CLEC18C GLIPR2	1.29e-04	15	126	3	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18C GLIPR2	1.29e-04	15	126	3	IPR001283
Domain	-	CLEC18A CLEC18C GLIPR2	1.29e-04	15	126	3	3.40.33.10
Domain	CAP_domain	CLEC18A CLEC18C GLIPR2	1.29e-04	15	126	3	IPR014044
Domain	Ago_hook	TNRC6C TNRC6A	1.35e-04	3	126	2	PF10427
Domain	NO_synthase	NOS2 NOS3	1.35e-04	3	126	2	PF02898
Domain	NOS_euk	NOS2 NOS3	1.35e-04	3	126	2	IPR012144
Domain	-	NOS2 NOS3	1.35e-04	3	126	2	3.90.340.10
Domain	TNRC6_PABC-bd	TNRC6C TNRC6A	1.35e-04	3	126	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6C TNRC6A	1.35e-04	3	126	2	IPR019486
Domain	NOS_N	NOS2 NOS3	1.35e-04	3	126	2	IPR004030
Domain	TNRC6-PABC_bdg	TNRC6C TNRC6A	1.35e-04	3	126	2	PF16608
Domain	NOS	NOS2 NOS3	1.35e-04	3	126	2	PS60001
Domain	LDLR_class-A_CS	MFRP SSPOP ST14 MALRD1	1.50e-04	40	126	4	IPR023415
Domain	CTCK_1	SSPOP MUC2 MUC5AC	2.27e-04	18	126	3	PS01185
Domain	Ldl_recept_a	MFRP SSPOP ST14 MALRD1	2.38e-04	45	126	4	PF00057
Domain	-	MFRP SSPOP ST14 MALRD1	2.59e-04	46	126	4	4.10.400.10
Domain	LDLRA_1	MFRP SSPOP ST14 MALRD1	3.05e-04	48	126	4	PS01209
Domain	CUB	MFRP CSMD2 ST14 CSMD1	3.31e-04	49	126	4	PF00431
Domain	LDrepeatLR_classA_rpt	MFRP SSPOP ST14 MALRD1	3.31e-04	49	126	4	IPR002172
Domain	LDLa	MFRP SSPOP ST14 MALRD1	3.31e-04	49	126	4	SM00192
Domain	LDLRA_2	MFRP SSPOP ST14 MALRD1	3.31e-04	49	126	4	PS50068
Domain	CUB	MFRP CSMD2 ST14 CSMD1	3.58e-04	50	126	4	SM00042
Domain	TRYPSIN_SER	KLK7 ST14 F12 CELA3B CELA3A	3.59e-04	90	126	5	IPR033116
Domain	-	MFRP CSMD2 ST14 CSMD1	4.16e-04	52	126	4	2.60.120.290
Domain	Sushi	PAPPA2 TPO CSMD2 CSMD1	4.16e-04	52	126	4	PF00084
Domain	CT	MUC2 MUC5AC OTOG	4.20e-04	22	126	3	SM00041
Domain	CUB	MFRP CSMD2 ST14 CSMD1	4.48e-04	53	126	4	PS01180
Domain	CCP	PAPPA2 TPO CSMD2 CSMD1	4.81e-04	54	126	4	SM00032
Domain	FN3_dom	PAPPA2 INSRR RIMBP3 TIE1 ASTN2 RIMBP3C RIMBP3B	5.45e-04	209	126	7	IPR003961
Domain	SUSHI	PAPPA2 TPO CSMD2 CSMD1	5.53e-04	56	126	4	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA2 TPO CSMD2 CSMD1	5.92e-04	57	126	4	IPR000436
Domain	CUB_dom	MFRP CSMD2 ST14 CSMD1	5.92e-04	57	126	4	IPR000859
Domain	FAD_binding_1	NOS2 NOS3	6.65e-04	6	126	2	PF00667
Domain	-	NOS2 NOS3	6.65e-04	6	126	2	1.20.990.10
Domain	FAD-binding_1	NOS2 NOS3	6.65e-04	6	126	2	IPR003097
Domain	NADPH_Cyt_P450_Rdtase_dom3	NOS2 NOS3	6.65e-04	6	126	2	IPR023173
Domain	TRYPSIN_HIS	KLK7 ST14 F12 CELA3B CELA3A	6.66e-04	103	126	5	IPR018114
Domain	TRYPSIN_SER	KLK7 ST14 F12 CELA3B CELA3A	7.59e-04	106	126	5	PS00135
Domain	TRYPSIN_HIS	KLK7 ST14 F12 CELA3B CELA3A	7.92e-04	107	126	5	PS00134
Domain	Peptidase_S1A	KLK7 ST14 F12 CELA3B CELA3A	1.01e-03	113	126	5	IPR001314
Domain	TRYPSIN_DOM	KLK7 ST14 F12 CELA3B CELA3A	1.10e-03	115	126	5	PS50240
Domain	Tryp_SPc	KLK7 ST14 F12 CELA3B CELA3A	1.18e-03	117	126	5	SM00020
Domain	Flavodoxin/NO_synth	NOS2 NOS3	1.23e-03	8	126	2	IPR008254
Domain	Flavdoxin-like	NOS2 NOS3	1.23e-03	8	126	2	IPR001094
Domain	FLAVODOXIN_LIKE	NOS2 NOS3	1.23e-03	8	126	2	PS50902
Domain	Flavodoxin_1	NOS2 NOS3	1.23e-03	8	126	2	PF00258
Domain	Trypsin_dom	KLK7 ST14 F12 CELA3B CELA3A	1.37e-03	121	126	5	IPR001254
Domain	Trypsin	KLK7 ST14 F12 CELA3B CELA3A	1.37e-03	121	126	5	PF00089
Domain	Peptidase_S1_PA	KLK7 ST14 F12 CELA3B CELA3A	1.48e-03	123	126	5	IPR009003
Domain	Ig_2	LILRA1 SEMA7A SIGLEC10 SIGLEC1	1.50e-03	73	126	4	PF13895
Domain	FN3	PAPPA2 INSRR TIE1 ASTN2 RIMBP3C RIMBP3B	1.61e-03	185	126	6	SM00060
Domain	EGF_Lam	LAMA5 CELSR3 PEAR1	1.68e-03	35	126	3	SM00180
Domain	Laminin_EGF	LAMA5 CELSR3 PEAR1	1.68e-03	35	126	3	PF00053
Domain	-	PAPPA2 LILRA1 SEMA7A CILP INSRR RIMBP3 TIE1 SIGLEC10 ASTN2 RIMBP3C SIGLEC1 RIMBP3B	1.77e-03	663	126	12	2.60.40.10
Domain	VWFC_1	SSPOP MUC2 MUC5AC	1.82e-03	36	126	3	PS01208
Domain	SH3_9	ARHGEF5 RIMBP3 RIMBP3C RIMBP3B	1.92e-03	78	126	4	PF14604
Domain	-	NOS2 NOS3	1.96e-03	10	126	2	3.40.50.360
Domain	Flavoprotein-like_dom	NOS2 NOS3	1.96e-03	10	126	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NOS2 NOS3	1.96e-03	10	126	2	IPR001709
Domain	C_TYPE_LECTIN_1	CLEC18A CLEC18C PKD1L2 PRG2	2.10e-03	80	126	4	PS00615
Domain	VWFC_2	SSPOP MUC2 MUC5AC	2.13e-03	38	126	3	PS50184
Domain	Laminin_EGF	LAMA5 CELSR3 PEAR1	2.13e-03	38	126	3	IPR002049
Domain	FN3	INSRR RIMBP3 TIE1 ASTN2 RIMBP3C RIMBP3B	2.32e-03	199	126	6	PS50853
Domain	Lectin_C	CLEC18A CLEC18C PKD1L2 PRG2	2.51e-03	84	126	4	PF00059
Domain	CLECT	CLEC18A CLEC18C PKD1L2 PRG2	2.51e-03	84	126	4	SM00034
Domain	C_TYPE_LECTIN_2	CLEC18A CLEC18C PKD1L2 PRG2	2.62e-03	85	126	4	PS50041
Domain	SH3_2	ARHGEF5 RIMBP3 RIMBP3C RIMBP3B	2.74e-03	86	126	4	PF07653
Domain	C-type_lectin-like	CLEC18A CLEC18C PKD1L2 PRG2	2.74e-03	86	126	4	IPR001304
Domain	SH3_2	ARHGEF5 RIMBP3 RIMBP3C RIMBP3B	2.74e-03	86	126	4	IPR011511
Domain	OxRdtase_FAD/NAD-bd	NOS2 NOS3	2.85e-03	12	126	2	IPR001433
Domain	NAD_binding_1	NOS2 NOS3	2.85e-03	12	126	2	PF00175
Domain	Ig-like_fold	PAPPA2 LILRA1 SEMA7A CILP INSRR RIMBP3 TIE1 SIGLEC10 ASTN2 RIMBP3C SIGLEC1 RIMBP3B	2.96e-03	706	126	12	IPR013783
Domain	C-type_lectin_CS	CLEC18A CLEC18C PRG2	3.04e-03	43	126	3	IPR018378
Domain	6-hairpin_glycosidase-like	LANCL1 AGL	3.35e-03	13	126	2	IPR008928
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.04e-07	4	130	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	5.08e-07	5	130	3	17855024
Pubmed	Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.	CPA2 CELA3B CELA3A	5.08e-07	5	130	3	27358403
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EP400 SEMA7A APBB3 LAMA5 TNRC6C WASHC2A ZBED3 ST14 RYR1 PKMYT1 TINAGL1 PHLDB1 LLGL2 MDN1 CELSR3 ZFYVE26 GAREM1	8.47e-07	1105	130	17	35748872
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LAMA5 SSPOP ITIH1 TINAGL1 CELA3B CELA3A PRG2	4.55e-06	175	130	7	28071719
Pubmed	Hereditary spastic paraplegia with mental impairment and thin corpus callosum in Tunisia: SPG11, SPG15, and further genetic heterogeneity.	SPG11 ZFYVE26	1.39e-05	2	130	2	18332254
Pubmed	Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice.	NOS2 NOS3	1.39e-05	2	130	2	18931027
Pubmed	Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.	NOS2 NOS3	1.39e-05	2	130	2	18849972
Pubmed	Nitric oxide overproduction derived from inducible nitric oxide synthase increases cardiomyocyte apoptosis in human atrial fibrillation.	NOS2 NOS3	1.39e-05	2	130	2	18585800
Pubmed	Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS.	NOS2 NOS3	1.39e-05	2	130	2	11435211
Pubmed	Single nucleotide polymorphisms in NOS2A and NOS3 genes are not associated with treatment response of non-small cell lung cancer patients following the definitive radiochemotherapy.	NOS2 NOS3	1.39e-05	2	130	2	22862164
Pubmed	Exercise-induced activation of cardiac sympathetic nerve triggers cardioprotection via redox-sensitive activation of eNOS and upregulation of iNOS.	NOS2 NOS3	1.39e-05	2	130	2	17259438
Pubmed	Inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) expression in fulminant hepatic failure.	NOS2 NOS3	1.39e-05	2	130	2	12399227
Pubmed	Nitric oxide stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells.	NOS2 NOS3	1.39e-05	2	130	2	18453977
Pubmed	Impaired lymphatic contraction associated with immunosuppression.	NOS2 NOS3	1.39e-05	2	130	2	22065738
Pubmed	Nitric oxide synthase and postischemic liver injury.	NOS2 NOS3	1.39e-05	2	130	2	11027558
Pubmed	Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.	CELA3B CELA3A	1.39e-05	2	130	2	27999401
Pubmed	eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia.	NOS2 NOS3	1.39e-05	2	130	2	27030287
Pubmed	Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via "imported" nitric oxide synthase activity.	NOS2 NOS3	1.39e-05	2	130	2	15723985
Pubmed	Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity.	NOS2 NOS3	1.39e-05	2	130	2	16093363
Pubmed	Nitric oxide, a key signaling molecule in the murine early embryonic heart.	NOS2 NOS3	1.39e-05	2	130	2	15132985
Pubmed	Association of NOS2 and NOS3 gene polymorphisms with susceptibility to type 2 diabetes mellitus and diabetic nephropathy in the Chinese Han population.	NOS2 NOS3	1.39e-05	2	130	2	27192959
Pubmed	Inducible but not endothelial nitric oxide synthase polymorphism is associated with susceptibility to rheumatoid arthritis in northwest Spain.	NOS2 NOS3	1.39e-05	2	130	2	15226517
Pubmed	Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation.	NOS2 NOS3	1.39e-05	2	130	2	18753139
Pubmed	Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.	NOS2 NOS3	1.39e-05	2	130	2	7479866
Pubmed	Mucolytic activity of bacterial and human chitinases.	MUC2 MUC5AC	1.39e-05	2	130	2	17321686
Pubmed	The NOS3 (27-bp repeat, intron 4) polymorphism is associated with susceptibility to osteomyelitis.	NOS2 NOS3	1.39e-05	2	130	2	16889995
Pubmed	Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.	MUC2 MUC5AC	1.39e-05	2	130	2	20731025
Pubmed	Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.	NOS2 NOS3	1.39e-05	2	130	2	12437348
Pubmed	The role of NOS2 and NOS3 in renal protein and arginine metabolism during early endotoxemia in mice.	NOS2 NOS3	1.39e-05	2	130	2	15547116
Pubmed	Nitric oxide synthase gene polymorphisms in Alzheimer's disease and dementia with Lewy bodies.	NOS2 NOS3	1.39e-05	2	130	2	11297817
Pubmed	The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.	FCGBP MUC2	1.39e-05	2	130	2	34126068
Pubmed	Elevated blood pressures in mice lacking endothelial nitric oxide synthase.	NOS2 NOS3	1.39e-05	2	130	2	8917564
Pubmed	Effects of coenzyme Q10 on the heart ultrastructure and nitric oxide synthase during hyperthyroidism.	NOS2 NOS3	1.39e-05	2	130	2	18274157
Pubmed	Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase.	NOS2 NOS3	1.39e-05	2	130	2	10981965
Pubmed	Nitric oxide synthase in healthy and inflamed human dental pulp.	NOS2 NOS3	1.39e-05	2	130	2	15044505
Pubmed	Nitric oxide synthases in infants and children with pulmonary hypertension and congenital heart disease.	NOS2 NOS3	1.39e-05	2	130	2	19912632
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD2 CSMD1	1.39e-05	2	130	2	24408017
Pubmed	Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.	NOS2 NOS3	1.39e-05	2	130	2	27665476
Pubmed	Serum inducible and endothelial nitric oxide synthase in coronary artery disease patients with Type 2 Diabetes mellitus.	NOS2 NOS3	1.39e-05	2	130	2	35647851
Pubmed	Nitric oxide synthases modulate progenitor and resident endothelial cell behavior in galactosemia.	NOS2 NOS3	1.39e-05	2	130	2	16356104
Pubmed	Participation of the mouse implanting trophoblast in nitric oxide production during pregnancy.	NOS2 NOS3	1.39e-05	2	130	2	10642561
Pubmed	Antisense evidence for two functionally active forms of nitric oxide synthase in brain microvascular endothelium.	NOS2 NOS3	1.39e-05	2	130	2	8702423
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.	MUC2 MUC5AC	1.39e-05	2	130	2	23832517
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.	MUC2 MUC5AC	1.39e-05	2	130	2	23832516
Pubmed	Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children.	NOS2 NOS3	1.39e-05	2	130	2	12631094
Pubmed	The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice.	NOS2 NOS3	1.39e-05	2	130	2	12730888
Pubmed	Thalidomide ameliorates portal hypertension via nitric oxide synthase independent reduced systolic blood pressure.	NOS2 NOS3	1.39e-05	2	130	2	25892862
Pubmed	Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.	NOS2 NOS3	1.39e-05	2	130	2	22000010
Pubmed	ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis.	SPG11 ZFYVE26	1.39e-05	2	130	2	30081747
Pubmed	Inducible and endothelial nitric oxide synthase genes polymorphism in inflammatory bowel disease.	NOS2 NOS3	1.39e-05	2	130	2	16634870
Pubmed	Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension.	NOS2 NOS3	1.39e-05	2	130	2	12381520
Pubmed	Is apoptosis the cause of noninsertional achilles tendinopathy?	NOS2 NOS3	1.39e-05	2	130	2	19741110
Pubmed	Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line.	NOS2 NOS3	1.39e-05	2	130	2	15492785
Pubmed	Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice.	NOS2 NOS3	1.39e-05	2	130	2	21154234
Pubmed	Dissociation between adipose nitric oxide synthase expression and tissue metabolism.	NOS2 NOS3	1.39e-05	2	130	2	17456572
Pubmed	Role of polymorphisms of inducible nitric oxide synthase and endothelial nitric oxide synthase in idiopathic environmental intolerances.	NOS2 NOS3	1.39e-05	2	130	2	25878398
Pubmed	Nicorandil mitigates folic acid-induced nephrotoxicity in mice: Role of iNOS and eNOS.	NOS2 NOS3	1.39e-05	2	130	2	33404076
Pubmed	Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study.	NOS2 NOS3	1.39e-05	2	130	2	22244784
Pubmed	Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes.	CELA3B CELA3A	1.39e-05	2	130	2	2460440
Pubmed	Deficiency of inducible and endothelial nitric oxide synthase results in diminished bone formation and delayed union and nonunion development.	NOS2 NOS3	1.39e-05	2	130	2	26555548
Pubmed	[Immunohistochemical study on expression of iNOS and eNOS during skin incised wound healing in mice].	NOS2 NOS3	1.39e-05	2	130	2	16259358
Pubmed	Role of nitric oxide synthase genes in hepatitis E virus infection.	NOS2 NOS3	1.39e-05	2	130	2	24215170
Pubmed	Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.	MUC2 MUC5AC	1.39e-05	2	130	2	17203232
Pubmed	Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II.	NOS2 NOS3	1.39e-05	2	130	2	11880293
Pubmed	[Effects of osmolarity on NO synthase activity in endothelial cells and its mechanism].	NOS2 NOS3	1.39e-05	2	130	2	21171409
Pubmed	Long-term survival after ischemic stroke in postmenopausal women is affected by an interaction between smoking and genetic variation in nitric oxide synthases.	NOS2 NOS3	1.39e-05	2	130	2	18648197
Pubmed	Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs.	NOS2 NOS3	1.39e-05	2	130	2	26799210
Pubmed	Structural basis for endothelial nitric oxide synthase binding to calmodulin.	NOS2 NOS3	1.39e-05	2	130	2	12574113
Pubmed	Sustained hypertension despite endothelial-specific eNOS rescue in eNOS-deficient mice.	NOS2 NOS3	1.39e-05	2	130	2	25680465
Pubmed	Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption.	NOS2 NOS3	1.39e-05	2	130	2	10205152
Pubmed	Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney.	NOS2 NOS3	1.39e-05	2	130	2	12682064
Pubmed	Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.	MUC2 MUC5AC	1.39e-05	2	130	2	12527922
Pubmed	Critical role of endothelial cell-derived nitric oxide synthase in sickle cell disease-induced microvascular dysfunction.	NOS2 NOS3	1.39e-05	2	130	2	16631534
Pubmed	Genetic removal of basal nitric oxide enhances contractile activity in isolated murine collecting lymphatic vessels.	NOS2 NOS3	1.39e-05	2	130	2	23420659
Pubmed	Expression of nitric oxide synthases in parathyroid gland adenoma and parathyroid gland hyperplasia.	NOS2 NOS3	1.39e-05	2	130	2	16136006
Pubmed	[Polymorphism of eNOS and iNOS Genes and Chronic Heart Failure in Patients With Ischemic Heart Disease].	NOS2 NOS3	1.39e-05	2	130	2	20459417
Pubmed	Doppler analysis and placental nitric oxide synthase expression during fetal growth restriction.	NOS2 NOS3	1.39e-05	2	130	2	18828052
Pubmed	Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation.	NOS2 NOS3	1.39e-05	2	130	2	10074942
Pubmed	Investigations on the inducible and endothelial nitric oxide synthases in human breast cancer cell line MCF-7 - estrogen has an influence on e-NOS, but not on i-NOS.	NOS2 NOS3	1.39e-05	2	130	2	16326029
Pubmed	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.	FCGBP MUC2	1.39e-05	2	130	2	19432394
Pubmed	Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.	NOS2 NOS3	1.39e-05	2	130	2	17099710
Pubmed	Exhaled nitric oxide and nitric oxide synthase expression in Hodgkin's disease.	NOS2 NOS3	1.39e-05	2	130	2	20074466
Pubmed	[The relationship between resting heart rate and single nucleotide polymorphism at 3 sites of nitric oxide synthase gene in the Chinese Han nationality population].	NOS2 NOS3	1.39e-05	2	130	2	17160951
Pubmed	Expressions and regulation of endothelial and inducible nitric oxide synthases in mouse uterus during the estrous cycle and early pregnancy.	NOS2 NOS3	1.39e-05	2	130	2	15970571
Pubmed	Role of nitric oxide synthases in elastase-induced emphysema.	NOS2 NOS3	1.39e-05	2	130	2	20956973
Pubmed	iNOS-dependent sweating and eNOS-dependent cutaneous vasodilation are evident in younger adults, but are diminished in older adults exercising in the heat.	NOS2 NOS3	1.39e-05	2	130	2	26586908
Pubmed	Nitric oxide synthase gene polymorphisms and prostate cancer risk.	NOS2 NOS3	1.39e-05	2	130	2	19168583
Pubmed	Nitric oxide synthase expression in human bladder cancer and its relation to angiogenesis.	NOS2 NOS3	1.39e-05	2	130	2	12937869
Pubmed	Endothelial dysfunction and altered mechanical and structural properties of resistance arteries in a murine model of graft-versus-host disease.	NOS2 NOS3	1.39e-05	2	130	2	24813168
Pubmed	Different vasculoprotective roles of NO synthase isoforms in vascular lesion formation in mice.	NOS2 NOS3	1.39e-05	2	130	2	11073861
Pubmed	NOS3 is involved in the increased protein and arginine metabolic response in muscle during early endotoxemia in mice.	NOS2 NOS3	1.39e-05	2	130	2	15644457
Pubmed	Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.	NOS2 NOS3	1.39e-05	2	130	2	9516116
Pubmed	Outcome after BCG treatment for urinary bladder cancer may be influenced by polymorphisms in the NOS2 and NOS3 genes.	NOS2 NOS3	1.39e-05	2	130	2	26298202
Pubmed	Inducible and endothelial nitric synthetase expression and nitrotyrosine accumulation in iris vasculature of patients with primary open-angle glaucoma: a pilot study.	NOS2 NOS3	1.39e-05	2	130	2	25564962
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD2 CSMD1	1.39e-05	2	130	2	27890662
Pubmed	Functional variants of eNOS and iNOS genes have no relationship to the portal hypertension in patients with liver cirrhosis.	NOS2 NOS3	1.39e-05	2	130	2	23452051
Pubmed	Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species.	NOS2 NOS3	1.39e-05	2	130	2	18091741
Pubmed	Expression of nitric oxide synthase isoforms in the human placenta is not altered by labor.	NOS2 NOS3	1.39e-05	2	130	2	14614209
Pubmed	In vivo glycosylation of mucin tandem repeats.	MUC2 MUC5AC	1.39e-05	2	130	2	11445551
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 TPO CSMD2 CSMD1	1.36e-04	57	83	4	1179
GeneFamily	Ataxins\|Trinucleotide repeat containing	EP400 TNRC6C TNRC6A	1.99e-04	25	83	3	775
GeneFamily	THO complex	THOC3 THOC6	4.31e-04	7	83	2	770
GeneFamily	WD repeat domain containing	THOC3 THOC6 LLGL2 WDR86 IFT80 SEC13	1.30e-03	262	83	6	362
Coexpression	NABA_MATRISOME	PAPPA2 TPO CLEC18A SEMA7A CILP LAMA5 CLEC18C MFRP SSPOP ST14 F12 ITIH1 TINAGL1 LMAN1L CELA3B CELA3A PRG2 ADAM33 ADAMTS14 MUC2 MUC5AC OTOG	4.95e-09	1008	130	22	MM17056
Coexpression	NABA_MATRISOME	PAPPA2 TPO CLEC18A SEMA7A CILP LAMA5 CLEC18C SSPOP ST14 F12 ITIH1 TINAGL1 LMAN1L CELA3B CELA3A PRG2 ADAM33 ADAMTS14 MUC2 MUC5AC OTOG	3.48e-08	1026	130	21	M5889
Coexpression	NABA_MATRISOME_ASSOCIATED	PAPPA2 TPO CLEC18A SEMA7A CLEC18C MFRP ST14 F12 ITIH1 LMAN1L CELA3B CELA3A ADAM33 ADAMTS14 MUC2 MUC5AC	8.17e-07	738	130	16	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	PAPPA2 TPO CLEC18A SEMA7A CLEC18C ST14 F12 ITIH1 LMAN1L CELA3B CELA3A ADAM33 ADAMTS14 MUC2 MUC5AC	5.00e-06	751	130	15	M5885
Coexpression	NABA_ECM_AFFILIATED	CLEC18A SEMA7A CLEC18C MFRP LMAN1L MUC2 MUC5AC	1.44e-05	158	130	7	MM17063
Coexpression	NABA_ECM_REGULATORS	PAPPA2 ST14 F12 ITIH1 CELA3B CELA3A ADAM33 ADAMTS14	2.58e-05	238	130	8	M3468
Coexpression	NABA_ECM_REGULATORS	PAPPA2 ST14 F12 ITIH1 CELA3B CELA3A ADAM33 ADAMTS14	2.90e-05	242	130	8	MM17062
Coexpression	GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP	TBX19 PHLDB1 MDN1 DSTYK ZFYVE26 SIGLEC1 IFT80	6.09e-05	198	130	7	M9035
Coexpression	GSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_DN	WRN APBB3 CHRNE SLC6A3 PKP2 KDM2A NBR1	6.09e-05	198	130	7	M8424
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	CILP MRGPRF SSC5D ZNF469 SIGLEC10 ADAMTS14	1.01e-05	168	130	6	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 APBB3 KCNE5 PRG2 ADAM33 RFT1	1.23e-05	174	130	6	eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 APBB3 KCNE5 PRG2 ADAM33 RFT1	1.23e-05	174	130	6	32fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCell	wk_20-22-Hematologic-Myeloid-Basophil\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ARHGAP9 ZNF683 PRG2 GLIPR2 PKP2 ZSWIM4	1.64e-05	183	130	6	93d821d5340caed0eef455d3d738be213ce5fff8
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIK4 ST14 SLC5A5 FCGBP CMTM5 CSMD1	1.64e-05	183	130	6	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIK4 ST14 SLC5A5 FCGBP CMTM5 CSMD1	1.64e-05	183	130	6	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO LAMA5 ST14 LLGL2 CRYGN PKP2	1.69e-05	184	130	6	61caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO LAMA5 ST14 LLGL2 CRYGN PKP2	1.69e-05	184	130	6	03da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO LAMA5 ST14 LLGL2 CRYGN PKP2	1.69e-05	184	130	6	9ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCell	facs-Trachea-nan-24m-Epithelial-mucus_secreting_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO LAMA5 ST14 LLGL2 CRYGN PKP2	1.74e-05	185	130	6	e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CILP KCNE5 GRIK4 ADARB1 SSC5D TENM4	1.74e-05	185	130	6	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LILRA1 ARHGAP9 GRIN2C RYR1 FCGBP SIGLEC1	2.15e-05	192	130	6	7e7383093efaadceadd4d1f900c2d39cd690102e
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.21e-05	193	130	6	c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.21e-05	193	130	6	6905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.21e-05	193	130	6	f73630725f093c646bdaf178c39505c04a16e2c6
ToppCell	P15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAPPA2 GRIK4 SSC5D TENM4 ADAM33 CSMD1	2.28e-05	194	130	6	5f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.34e-05	195	130	6	4d7ca21f14730e1b6d0473bc1a11aa626db948f3
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.34e-05	195	130	6	8727554ef047ca7f1d4b888a8468f148c64a6918
ToppCell	droplet-Trachea-nan-3m-Epithelial-epithelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO ST14 SLC5A5 TENM4 CRYGN PKP2	2.34e-05	195	130	6	9f0ee826d4f0997aee8d63284ed24549bbdf6a28
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF703 ST14 F12 LLGL2 PKP2 NOS2	2.48e-05	197	130	6	c0250509836f1be04f5e54386191d7bb1e1da652
ToppCell	distal-3-mesenchymal-Fibromyocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 IP6K3 MRGPRF CSMD2 SSC5D ADAM33	2.55e-05	198	130	6	dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MRGPRF CSMD2 SSC5D ZNF469 TENM4 CRYGN	2.55e-05	198	130	6	0cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MRGPRF CSMD2 SSC5D ZNF469 TENM4 CRYGN	2.55e-05	198	130	6	e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell	Skin-Mesangial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	IP6K3 MRGPRF SSPOP TINAGL1 CHST7 NOS3	2.63e-05	199	130	6	bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell	Calu_3\|World / Cell line, Condition and Strain	SEMA7A LAMA5 ST14 TINAGL1 LLGL2 MUC5AC	2.70e-05	200	130	6	a549aa08aeefe905653266dae3936094ff55f8e4
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MRGPRF PTGES3L TINAGL1 ASB5 ADAMTS14	2.72e-05	120	130	5	a320799ab5f2ce872e038b15841a23174c5436e8
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CLEC18A FCGBP PKP2 ADAMTS14 MUC2	3.57e-05	127	130	5	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D231\|Adult / Lineage, Cell type, age group and donor	SMKR1 PPP1R13B LLGL2 CELSR3 FAM151A	4.30e-05	132	130	5	8d30b71776f5f6da55dc78e0c5cb27be460004e3
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPA2 ANKRD63 CHRNE RIMBP3 TENM4	7.40e-05	148	130	5	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APBB3 KCNE5 PRG2 ADAM33 RFT1	8.14e-05	151	130	5	523dcd243c285a6b74830a93c82cca8784edd658
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APBB3 KCNE5 PRG2 ADAM33 RFT1	8.14e-05	151	130	5	f3406094ce79cc80398b82d58ca6fd87a96e68d4
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA7A TINAGL1 TIE1 NOS2 NOS3	1.01e-04	158	130	5	78b48b110b777bcc4c07cd23388bee911c0231d6
ToppCell	Adult-Immune-mast_cell-D175\|Adult / Lineage, Cell type, age group and donor	PAPPA2 SEMA7A ARHGAP9 SLC5A5 PKP2	1.04e-04	159	130	5	9f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCell	Healthy_Control-Lymphoid-Plasma\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SEMA7A PKP2 IFT80 ADAMTS14 ZSWIM4	1.17e-04	163	130	5	2913ccdd4613472cd82077d4993e1d9f8b223398
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MRGPRF ADARB1 SLC5A5 TINAGL1 CSMD1	1.17e-04	163	130	5	51dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell	Healthy_Control-Lymphoid-Plasma-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SEMA7A PKP2 IFT80 ADAMTS14 ZSWIM4	1.17e-04	163	130	5	b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LILRA1 PPP1R13B WASHC2A SSC5D AGL	1.20e-04	164	130	5	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	F12 PKMYT1 ZNF469 GLIPR2 ADAM33	1.31e-04	167	130	5	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	CILP CLEC18C WASHC2A ZPR1 GAREM1	1.34e-04	168	130	5	d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLEC18A CSMD2 TF CRYGN CSMD1	1.46e-04	171	130	5	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MRGPRF ADARB1 TINAGL1 ADAM33 MUC5AC	1.54e-04	173	130	5	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA7A PPP1R13B TINAGL1 TIE1 NOS3	1.58e-04	174	130	5	40bb87d219aafab0357ab0d797efd38085fc0312
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LILRA1 LANCL1 ZNF683 GRIN2C TINAGL1	1.58e-04	174	130	5	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A CPA2 SPG11 GRIN2C WDR86	1.63e-04	175	130	5	91cb819a1786020713b7e64480de0545380daae9
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLK7 LAMA5 TNRC6A PKP2 ADAM33	1.63e-04	175	130	5	f5451c29c487b998778e50349b3d774d5e20fd28
ToppCell	18-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	SEMA7A CPA2 TF PRG2 SIGLEC10	1.63e-04	175	130	5	7130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	MRGPRF ZNF683 RYR1 CRYGN WDR86	1.63e-04	175	130	5	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	18-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	SEMA7A CPA2 TF PRG2 SIGLEC10	1.63e-04	175	130	5	cc476b4244442418b8f21721a82a36209b556b36
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-tDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KCNE5 ST14 EVPLL ADAM33 MUC5AC	1.67e-04	176	130	5	fb07a047a3a7a8d03bfcc28eea3da2eaa0f6b733
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A SSPOP TINAGL1 TIE1 OTOG	1.67e-04	176	130	5	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	LILRA1 LANCL1 ZNF683 GRIN2C TINAGL1	1.67e-04	176	130	5	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	PBMC-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	LAMA5 PPP1R13B ZBED3 SIGLEC10 PKP2	1.71e-04	177	130	5	974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MRGPRF KCNE5 TINAGL1 ADAM33 CSMD1	1.76e-04	178	130	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	SEMA7A MRGPRF SSC5D ZNF469 ADAMTS14	1.76e-04	178	130	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF703 KLK7 SEMA7A MRGPRF PCARE	1.81e-04	179	130	5	c1c0b7186a0eab8c76404b95f1cf8d64b1b45cb1
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF703 SLC6A3 LLGL2 PKP2 NOS2	1.81e-04	179	130	5	6405010e8136a4d9bab356f628e36e3194911112
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SSPOP RYR1 ZNF469 SIGLEC10 SIGLEC1	1.85e-04	180	130	5	66c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCell	Thalamus-Macroglia\|Thalamus / BrainAtlas - Mouse McCarroll V32	PPP1R13B SSPOP PHLDB1 RNF5 CMTM5	1.90e-04	181	130	5	4f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F12 ITIH1 NAGS PKP2 GAREM1	1.95e-04	182	130	5	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-tDC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KCNE5 ST14 ADAM33 RIMBP3C SIGLEC1	1.95e-04	182	130	5	ad5c99ec62cdab347d3a03c971d981e3b924020c
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA2 ST14 CELA3B FCGBP TENM4	1.95e-04	182	130	5	b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F12 ITIH1 NAGS PKP2 GAREM1	1.95e-04	182	130	5	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F12 ITIH1 NAGS PKP2 GAREM1	1.95e-04	182	130	5	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA2 ST14 CELA3B FCGBP TENM4	1.95e-04	182	130	5	cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LINC00482 ARHGEF5 TINAGL1 TIE1 PEAR1	2.00e-04	183	130	5	6cdadb3ece45a94a2915063aa461048e1d371ccd
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F12 ITIH1 AGL PKP2 GAREM1	2.00e-04	183	130	5	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LINC00482 ARHGEF5 TINAGL1 TIE1 PEAR1	2.00e-04	183	130	5	8714d3e7663c93cdf9b25b647353572e136f30c3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LINC00482 ARHGEF5 TINAGL1 TIE1 PEAR1	2.00e-04	183	130	5	c7fc96ac1d5d31ccefe0c1fc6ec76c7d8607a172
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	MRGPRF ITIH1 TINAGL1 ASB5 CMTM5	2.05e-04	184	130	5	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD1L2 SSPOP TENM4 CSMD1 OTOG	2.05e-04	184	130	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ST14 SLC5A5 CELA3B FCGBP PKP2	2.05e-04	184	130	5	204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPO KIAA0087 TINAGL1 TIE1 NOS3	2.05e-04	184	130	5	842473fa415575441b595073a994b6d621169776
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	TINAGL1 TIE1 PRG2 NOS2 NOS3	2.05e-04	184	130	5	7e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD1L2 SSPOP TENM4 CSMD1 OTOG	2.05e-04	184	130	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ST14 SLC5A5 CELA3B FCGBP PKP2	2.05e-04	184	130	5	9365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD1L2 SSPOP TENM4 CSMD1 OTOG	2.05e-04	184	130	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST14 SLC5A5 CELA3B FCGBP PKP2	2.05e-04	184	130	5	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST14 SLC5A5 CELA3B FCGBP PKP2	2.05e-04	184	130	5	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	E12.5-Endothelial-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEMA7A CPA2 TINAGL1 TIE1 NOS3	2.10e-04	185	130	5	e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADARB1 TINAGL1 TIE1 NOS2 NOS3	2.10e-04	185	130	5	62cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCell	E12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEMA7A CPA2 TINAGL1 TIE1 NOS3	2.10e-04	185	130	5	0bccc424d0466f7f82baa00127c733640a2d50fb
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF5 LAMA5 TINAGL1 TUBGCP6 PEAR1	2.10e-04	185	130	5	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IP6K3 TF PHLDB1 CMTM5 ADAMTS14	2.10e-04	185	130	5	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADARB1 TINAGL1 TIE1 NOS3 PEAR1	2.16e-04	186	130	5	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IP6K3 TF PHLDB1 CMTM5 ADAMTS14	2.16e-04	186	130	5	d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADARB1 TINAGL1 TIE1 NOS3 PEAR1	2.16e-04	186	130	5	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A TINAGL1 TIE1 NOS2 NOS3	2.21e-04	187	130	5	7abc174a06bf07b5f6efe0a370fbb1c23e0079b3
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A TINAGL1 TIE1 NOS2 NOS3	2.21e-04	187	130	5	f9863428943b695f26bd680e6fc5aeb38ec3422f
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNE5 SSC5D TENM4 MDN1 ASB5	2.21e-04	187	130	5	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	facs-Aorta-Heart-3m-Endothelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A PPP1R13B TINAGL1 TIE1 NOS3	2.21e-04	187	130	5	df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A TINAGL1 TIE1 NOS2 NOS3	2.21e-04	187	130	5	b0a2e417b4eb9a185033e89c5df3431c11488688
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 MRGPRF GRIK4 SSC5D CSMD1	2.21e-04	187	130	5	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 MRGPRF GRIK4 SSC5D CSMD1	2.21e-04	187	130	5	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	droplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IP6K3 SEMA7A TINAGL1 TIE1 NOS3	2.27e-04	188	130	5	67c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A TINAGL1 TIE1 NOS2 NOS3	2.27e-04	188	130	5	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA7A PPP1R13B TINAGL1 TIE1 NOS3	2.27e-04	188	130	5	20072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCell	368C-Epithelial_cells-Epithelial-I_(AT1)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 LLGL2 TRMT44 SIGLEC10 NBR1	2.27e-04	188	130	5	c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell	facs-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA7A PPP1R13B TINAGL1 TIE1 NOS3	2.27e-04	188	130	5	dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCell	368C-Epithelial_cells-Epithelial-I_(AT1)\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 LLGL2 TRMT44 SIGLEC10 NBR1	2.27e-04	188	130	5	9155b9a92496e75646778c025b02947e9e9ec73a
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	CILP MRGPRF SSC5D ADAM33 PEAR1	2.27e-04	188	130	5	c90669b51e1902fe7726555290c91c92a911df83
Drug	ketamine	KLK7 GRIK4 GRIN2C F12 RYR1 CHRNE SLC6A3 NOS2 NOS3	1.68e-05	262	127	9	CID000003821
Drug	N,N-dimethylarginine	NOS2 NOS3	3.09e-05	2	127	2	DB01686
Drug	6 Ni	NOS2 NOS3	3.09e-05	2	127	2	CID000024239
Drug	3 h x	NOS2 NOS3	3.09e-05	2	127	2	CID016058621
Drug	DB02077	NOS2 NOS3	3.09e-05	2	127	2	CID000656912
Drug	AC1LCVOW	NOS2 NOS3	3.09e-05	2	127	2	CID000656910
Drug	5-nitroindazole	NOS2 NOS3	3.09e-05	2	127	2	CID000021501
Drug	5-chloro-2-mercaptobenzothiazole	TPO SLC5A5	3.09e-05	2	127	2	ctd:C539674
Drug	AC1NRAON	NOS2 NOS3	3.09e-05	2	127	2	CID005288020
Drug	DB07388	NOS2 NOS3	3.09e-05	2	127	2	CID011149707
Drug	AC1L96OZ	NOS2 NOS3	3.09e-05	2	127	2	CID000439092
Drug	AC1NRAUH	NOS2 NOS3	3.09e-05	2	127	2	CID005288100
Drug	ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE	NOS2 NOS3	3.09e-05	2	127	2	DB07388
Drug	NSC-10379	NOS2 NOS3	3.09e-05	2	127	2	CID000223131
Drug	hard metal	NOS2 NOS3	3.09e-05	2	127	2	ctd:C080121
Drug	Ethylisothiourea	NOS2 NOS3	3.09e-05	2	127	2	DB02234
Drug	7-Nitroindazole	NOS2 NOS3	3.09e-05	2	127	2	DB02207
Drug	5-Nitroindazole	NOS2 NOS3	3.09e-05	2	127	2	DB04534
Drug	6-Nitroindazole	NOS2 NOS3	3.09e-05	2	127	2	DB03100
Drug	l956	SIGLEC1 NOS2 NOS3	7.34e-05	15	127	3	CID000017814
Drug	martentoxin, Buthus martensi	NOS2 NOS3	9.23e-05	3	127	2	ctd:C471035
Drug	NCX 6560	NOS2 NOS3	9.23e-05	3	127	2	ctd:C524539
Drug	3-Bromo-7-Nitroindazole	NOS2 NOS3	9.23e-05	3	127	2	DB01997
Drug	r142	NOS2 NOS3	9.23e-05	3	127	2	CID002734672
Drug	sodium perchlorate	TPO SLC5A5	9.23e-05	3	127	2	ctd:C031068
Drug	N-(3-(Aminomethyl)Benzyl)Acetamidine	NOS2 NOS3	9.23e-05	3	127	2	DB02044
Disease	cystitis (is_marker_for)	MUC2 MUC5AC	1.59e-05	2	118	2	DOID:1679 (is_marker_for)
Disease	Coronary Artery Vasospasm	ARHGAP9 NOS3	4.74e-05	3	118	2	C0010073
Disease	sputum mucin-5B amount	MUC2 MUC5AC	4.74e-05	3	118	2	OBA_2050332
Disease	pulmonary edema (biomarker_via_orthology)	NOS2 NOS3	9.46e-05	4	118	2	DOID:11396 (biomarker_via_orthology)
Disease	congenital hypothyroidism (is_implicated_in)	TPO SLC5A5	9.46e-05	4	118	2	DOID:0050328 (is_implicated_in)
Disease	diabetic angiopathy (biomarker_via_orthology)	NOS2 NOS3	9.46e-05	4	118	2	DOID:11713 (biomarker_via_orthology)
Disease	Bipolar Disorder	TPO GRIK4 ADARB1 ITIH1 SLC6A3 TENM4 ASTN2 CSMD1 NOS3	1.32e-04	477	118	9	C0005586
Disease	renal hypertension (implicated_via_orthology)	NOS2 NOS3	1.57e-04	5	118	2	DOID:1073 (implicated_via_orthology)
Disease	mucositis (biomarker_via_orthology)	MUC2 NOS2	1.57e-04	5	118	2	DOID:0080178 (biomarker_via_orthology)
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC5AC	1.57e-04	5	118	2	DOID:3030 (is_marker_for)
Disease	leucine measurement	CLEC18C MALRD1 ZPR1 PKP2	2.14e-04	73	118	4	EFO_0009770
Disease	Thyroid Dyshormonogenesis 1	TPO SLC5A5	2.35e-04	6	118	2	C1848805
Disease	bipolar disorder, schizophrenia, schizoaffective disorder	ITIH1 CSMD1	2.35e-04	6	118	2	EFO_0005411, MONDO_0004985, MONDO_0005090
Disease	Goiter	TPO SLC5A5	3.29e-04	7	118	2	C0018021
Disease	valine measurement	CLEC18C MALRD1 ZPR1	5.53e-04	40	118	3	EFO_0009792
Disease	bringing up phlegm, sputum or mucus on most days, self-reported	MUC2 MUC5AC	5.60e-04	9	118	2	EFO_0009824
Disease	Hepatic Insufficiency	NOS2 NOS3	5.60e-04	9	118	2	C1306571
Disease	colitis (biomarker_via_orthology)	MUC2 NOS2 NOS3	6.39e-04	42	118	3	DOID:0060180 (biomarker_via_orthology)
Disease	response to angiotensin-converting enzyme inhibitor, Cough	WRN PKD1L2 CSMD1	8.35e-04	46	118	3	EFO_0005325, HP_0012735
Disease	Sodium measurement	MFRP IFT80	8.52e-04	11	118	2	C0337443
Disease	Adverse Event by CTCAE Category	MFRP IFT80	8.52e-04	11	118	2	C1879645
Disease	triacylglycerol 54:9 measurement	CRYGN ZPR1	1.02e-03	12	118	2	EFO_0010427
Disease	Essential Hypertension	NOS2 NOS3	1.02e-03	12	118	2	C0085580
Disease	tRNA (guanine-N(7)-)-methyltransferase measurement	F12 ZPR1	1.20e-03	13	118	2	EFO_0802162
Disease	triacylglycerol 48:4 measurement	TENM4 PRG2	1.40e-03	14	118	2	EFO_0010407
Disease	asthma (is_marker_for)	PRG2 ADAM33 MUC5AC NOS2	1.67e-03	126	118	4	DOID:2841 (is_marker_for)
Disease	cystic fibrosis (is_marker_for)	MUC2 MUC5AC NOS2	1.99e-03	62	118	3	DOID:1485 (is_marker_for)
Disease	Necrotizing Enterocolitis	NOS2 NOS3	2.07e-03	17	118	2	C0520459
Disease	triacylglycerol 48:1 measurement	ZPR1 CSMD1	2.07e-03	17	118	2	EFO_0010404
Disease	otitis media (biomarker_via_orthology)	MUC5AC NOS2	2.07e-03	17	118	2	DOID:10754 (biomarker_via_orthology)
Disease	cholangiocarcinoma (is_marker_for)	MUC2 MUC5AC NOS2	2.17e-03	64	118	3	DOID:4947 (is_marker_for)
Disease	Gastric ulcer	NOS2 NOS3	2.33e-03	18	118	2	C0038358
Disease	Alcohol abuse	TF SLC6A3 TBX19	2.48e-03	67	118	3	C0085762
Disease	cortical surface area change measurement, age at assessment	KIAA0087 TF	2.59e-03	19	118	2	EFO_0008007, EFO_0021503
Disease	Osteoarthritis of hip	ITIH1 ASTN2	2.87e-03	20	118	2	C0029410
Disease	Schizophrenia	GRIK4 GRIN2C CSMD2 ADARB1 TF ITIH1 SLC6A3 TENM4 ASTN2 CSMD1	2.92e-03	883	118	10	C0036341
Disease	gastric ulcer (biomarker_via_orthology)	MUC5AC NOS3	3.17e-03	21	118	2	DOID:10808 (biomarker_via_orthology)
Disease	platelet component distribution width	SMKR1 LAMA5 CHRNE LMAN1L ZPR1 ADAM33 SIGLEC1 NOS3 PEAR1	3.37e-03	755	118	9	EFO_0007984
Disease	Amphetamine-Related Disorders	SLC6A3 ASTN2 CSMD1	3.41e-03	75	118	3	C0236733
Disease	Amphetamine Abuse	SLC6A3 ASTN2 CSMD1	3.41e-03	75	118	3	C0236807
Disease	Amphetamine Addiction	SLC6A3 ASTN2 CSMD1	3.41e-03	75	118	3	C0236804
Disease	triacylglycerol 48:2 measurement	ZPR1 CSMD1	3.48e-03	22	118	2	EFO_0010405
Disease	triacylglycerol 48:3 measurement	ZPR1 CSMD1	3.48e-03	22	118	2	EFO_0010406
Disease	impotence (biomarker_via_orthology)	NOS2 NOS3	3.48e-03	22	118	2	DOID:1875 (biomarker_via_orthology)
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	TPRX1 CSMD1	3.48e-03	22	118	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	Mental Depression	CSMD2 SLC6A3 TBX19 NOS2 NOS3	3.61e-03	254	118	5	C0011570
Disease	asthma (is_implicated_in)	ADAM33 MUC2 NOS2 NOS3	3.70e-03	157	118	4	DOID:2841 (is_implicated_in)
Disease	arginine measurement	TINAGL1 CSMD1	3.80e-03	23	118	2	EFO_0020990
Disease	QRS duration, response to sulfonylurea	MDN1 CSMD1	3.80e-03	23	118	2	EFO_0005055, EFO_0007922
Disease	Depression, Bipolar	GRIK4 ITIH1 TENM4	3.95e-03	79	118	3	C0005587

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGRGWHAGLCSTHEQ	FAM228A	186	Q86W67
AHLACNEGNWGPHLV	EP400	1131	Q96L91
NEGNWGPHLVVVRSC	EP400	1136	Q96L91
LSGRHDQWVPGCQVE	C1orf167	226	Q5SNV9
GSHVRECLANGLWSG	CSMD1	2656	Q96PZ7
WNSAVLRCEAPCGGH	CSMD2	741	Q7Z408
NGLWSGSEVRCLAGH	CSMD2	2701	Q7Z408
NSGGHAKTRPACQDW	ARHGEF5	871	Q12774
PSHWAAGDGPTQERC	BIRC7	16	Q96CA5
SLCVGVDPNRNWDAG	CPA2	246	P48052
TLEQQCQQLWGPGSH	ADAM33	521	Q9BZ11
CNNAEAHSWLRLGGP	C1orf147	116	Q96MC9
AAHGRSKSANDGNWP	PPP1R13B	376	Q96KQ4
RHLCVRSDWGQSEGP	ASTN2	546	O75129
GNPSRSLEQVCRWAH	ADAMTS14	326	Q8WXS8
EGQRHRQGTWTAAFC	CHRNE	396	Q04844
HGTCVQALTGPWGRA	ANKRD63	166	C9JTQ0
CEQGWPARLAHIAVG	RFT1	491	Q96AA3
SDLHTGRGGPCTQWL	RIMBP3B	506	A6NNM3
SDLHTGRGGPCTQWL	RIMBP3C	506	A6NJZ7
EHQCQSGLALLGTPW	MFRP	546	Q9BY79
QGPLHHGVCSTWLNS	NOS2	936	P35228
LLSCGGNWYRPLNSH	MDN1	446	Q9NU22
SLEWANTCGIQGRHQ	LINS1	46	Q8NG48
SSRHCPSLWAGTNGG	LLGL2	726	Q6P1M3
GDNRDLLVHWCHGAP	LANCL1	266	O43813
SCWFIHNNGAGLIDG	ITIH1	886	P19827
HGNRRVSGNPISVCW	KIAA0087	46	Q14695
QARPDGGWALDASCQ	LMAN1L	346	Q9HAT1
QACAEHEWAPGGALT	KCNE5	96	Q9UJ90
FSRQCSHAGGRPGNW	MUC2	271	Q02817
ARCHLSCPEGLWGVN	PEAR1	561	Q5VY43
GACNNRDHPRWGASN	TPO	156	P07202
GWPAALQRSQHTQCL	FAM205A	536	Q6ZU69
GWPAALQRSQHTQCL	FAM205BP	266	Q63HN1
GQPVHALQGCTWQLS	EVPLL	181	A8MZ36
VNLHGCRDLGGDWAP	GAREM1	401	Q9H706
VNLHEGNTWCPSSLG	HEATR6	351	Q6AI08
CARGSHPWQVALLSG	KLK7	36	P49862
QGCDSGSAEQHSPAW	TUBGCP6	841	Q96RT7
NQCGASPGEARHWLT	NAGS	111	Q8N159
ASNPAHNGRVCSTWG	MUC5AC	71	P98088
RQCTHAGGLPQDWRG	MUC5AC	316	P98088
AGRVWQGHANASFCP	LAMA5	1321	O15230
TQAGVQWCNHGSLQP	ADARB1	471	P78563
SNGSDCTLAQWPHAQ	IP6K3	116	Q96PC2
SGAWVCFNHPDFRGQ	CRYGN	46	Q8WXF5
SHWNCGAPGQDTKAQ	DSTYK	316	Q6XUX3
AGRPSDLEQGCSWAN	PKD1L2	196	Q7Z442
TELCIQHGWTPGNGR	NOS3	271	P29474
AAHQPWSRGGHCVAL	PRG2	186	P13727
ADNSCVWASRPGGLL	PFN3	26	P60673
FASRAGLGACWHPQC	PRICKLE3	201	O43900
ACGGPIQHLWQNTAA	MALRD1	166	Q5VYJ5
GHWDQNVSCLPVDCG	PAPPA2	1451	Q9BXP8
QCAAFWCQPHAGGLS	APBB3	386	O95704
WCQPHAGGLSEAVQA	APBB3	391	O95704
GGHLWEQGHVSPCAR	LINC00482	231	Q8N8I6
SVEAHCGAVLAGRWN	IFT80	101	Q9P2H3
RGSHNGQVWDPQCAP	KDM2A	431	Q9Y2K7
PESSRGQCGENLAWA	GLIPR2	56	Q9H4G4
ESCLQQLATHPGHWG	FAM151A	396	Q8WW52
ACQAAGGHVEPWRTE	FCGBP	1511	Q9Y6R7
SACQAAGGQVEPWRN	FCGBP	2711	Q9Y6R7
VSACQAAGGHVEPWR	FCGBP	3911	Q9Y6R7
LNCPTEDGGWQVHGV	CELA3A	221	P09093
VTQGQGSWADRSPLH	ASB5	61	Q8WWX0
LNCPTEDGGWQVHGV	CELA3B	221	P08861
WLEGQPQDAVGRSHS	DNAJC17	246	Q9NVM6
EHVGPDACGTQSWNL	INSRR	531	P14616
GVAGCTRGHRNWVPS	FIMP	6	Q96LL3
SPAHCSARQANVHWG	GPATCH2L	391	Q9NWQ4
SARQANVHWGPPCSR	GPATCH2L	396	Q9NWQ4
PGLAEQHGVWTARDC	CELSR3	2486	Q9NYQ7
KPLSCGSAQIWQHGT	GRIK4	331	Q16099
PCTGNQQSLAHSRLW	RYR1	3971	P21817
EPSNCWSDLDGGNHT	LRRFIP1	406	Q32MZ4
RQSGHTWQQSPFCLG	PCARE	391	A6NGG8
ELLGWTHGLCGNNNA	OTOG	276	Q6ZRI0
QGWGPRAVLHCSEHL	MROH5	541	Q6ZUA9
RNWGLGGHAFCRNPD	F12	256	P00748
NNAHTIGCNAVSWAP	SEC13	146	P55735
RGETTLWNPGCDHAG	VARS1	371	P26640
LWNPGCDHAGIATQV	VARS1	376	P26640
RWHQRCQPSGATNGL	SLC35G5	26	Q96KT7
CVTRAWAAEHGAGPQ	TRMT44	566	Q8IYL2
LIHEPLDQGNCAGSW	TINAGL1	216	Q9GZM7
VRSDAGHWNAPCLGG	TNRC6C	1626	Q9HCJ0
VGQLWSQHQRPSATC	SSPOP	181	A2VEC9
GGHWCPNILTAYQER	SSPOP	3981	A2VEC9
DLGQGHPASSWQDSL	RNF5	151	Q99942
ARWGQQAHSPLGTAA	ENTPD6	81	O75354
QCLNSQPRTHGWSRA	LILRA1	166	O75019
LSHKGQQFGPRVWCS	NBR1	461	Q14596
MAGNCSWEAHPGNRN	MRGPRF	1	Q96AM1
SDLHTGRGGPCTQWL	RIMBP3	506	Q9UFD9
GRDGLQSSCHVLWAP	WRN	856	Q14191
PWGRSNCDHSEDAGL	SSC5D	281	A1L4H1
GQVVHGSPREGFWCL	CILP	106	O75339
GAEHCPGLQRSLGVW	CHST7	41	Q9NS84
DRINWPCLLQGHGQS	CMTM5	86	Q96DZ9
ICQFAQEHISRWGPG	CLEC18A	431	A5D8T8
ICQFAQEHISRWGPG	CLEC18C	431	Q8NCF0
AQEARGSCNWQAHLP	TMEM270	51	Q6UE05
GSCNWQAHLPLGAAA	TMEM270	56	Q6UE05
HPSGHWATCRLCGEQ	ZBED3	61	Q96IU2
RNSCLAWHRGAPAGE	ZNF837	126	Q96EG3
NGWGRCSIPIHALEA	SPG11	521	Q96JI7
EHCGWNNTEIQSAGR	ZPR1	81	O75312
GIWENNSDLGSAGHC	ZFP28	256	Q8NHY6
NEPLPHSCNWVAASG	ZNF703	451	Q9H7S9
CSLHQAWGGPGCRAQ	TPRX1	71	Q8N7U7
SCHTGLGRSAGWNIP	TF	136	P02787
CGQSIHQCLPSNWTG	ERVFRD-1	301	P60508
GPSLQQHCEAWGASL	PKMYT1	191	Q99640
WTPCVGHDGGRDQQE	SLC5A5	626	Q92911
GWRGSQCQEACAPGH	TIE1	296	P35590
RGVNSHNPCGTSWIE	TECPR1	316	Q7Z6L1
NNSWNSPNCSDAHPG	SLC6A3	181	Q01959
GQGHICGASLISPNW	ST14	636	Q9Y5Y6
RGHGDSVDQLCWHPS	THOC3	96	Q96J01
RPHNGRWIGCLATDS	THOC6	216	Q86W42
GNGRCTLDLNGWHCV	TENM4	806	Q6N022
LACGTNARHPSCWNL	SEMA7A	141	O75326
NARHPSCWNLVNGTV	SEMA7A	146	O75326
LDAWEQHLDPNSGRC	ARHGAP9	216	Q9BRR9
HNGRWLQEGPAASLS	SIGLEC1	1296	Q9BZZ2
AEAQCQWDALHGAAP	PHLDB1	1061	Q86UU1
RWHQCCQPSDATNGL	SLC35G6	26	P0C7Q6
NVADCLHLRGFHWPG	SMKR1	41	H3BMG3
QERHAQSKAGPWACG	ZNF469	3136	Q96JG9
HPSEQDGERGTLWQC	THUMPD3	491	Q9BV44
IAQWADGAISPNGHR	WASHC2A	1066	Q641Q2
LNCSPDHIRRGSCWG	PTGES3L	6	E9PB15
SHLGGWIFSNPDGVC	TBX19	241	O60806
CEAWNVHGAQSGSIL	SIGLEC10	521	Q96LC7
CADHRGGINWLSLSP	WDR86	11	Q86TI4
GTGLCHWPLQNALVD	ZFYVE26	181	Q68DK2
RSRNGWPGAVAHACN	PKP2	466	Q99959
WPGAVAHACNPSTLG	PKP2	471	Q99959
DLNHWNGAGLSGTNC	TNRC6A	1896	Q8NDV7
PLASLACLAQWHQGA	ZNF683	461	Q8IZ20
DPTAGAGIEDANCWH	ZSWIM4	241	Q9H7M6
DLGHPFCNNLRSGDW	AGL	951	P35573
GGHPHNWTAISRECL	NDC1	356	Q9BTX1
ACQEGEQAGAPAWQH	GRIN2C	1131	Q14957