Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DYNC1H1 HTT	3.90e-04	37	77	3	GO:0045505
GeneOntologyMolecularFunction	volume-sensitive anion channel activity	TTYH1 LRRC8A	5.19e-04	9	77	2	GO:0005225
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51E2 OR2A14 ADGRG5 VIPR2 OR51B5 OR10H3 OR51Q1 OR51B6 ADGRL1 ADGRA1 OR51B4	5.55e-04	884	77	11	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	TLR10 OR51E2 OR2A14 ADGRG5 VIPR2 OR51B5 IGF2R OR10H3 OR51Q1 OR51B6 ADGRL1 ADGRA1 PLXND1 OR51B4	6.00e-04	1353	77	14	GO:0004888
Domain	Protein_Kinase_C_mu-related	PRKD3 PRKD1	5.15e-05	3	78	2	IPR015727
Domain	G_PROTEIN_RECEP_F2_2	ADGRG5 VIPR2 ADGRL1 ADGRA1	5.60e-05	50	78	4	PS00650
Domain	7tm_2	ADGRG5 VIPR2 ADGRL1 ADGRA1	5.60e-05	50	78	4	PF00002
Domain	GPCR_2_secretin-like	ADGRG5 VIPR2 ADGRL1 ADGRA1	1.15e-04	60	78	4	IPR000832
Domain	GPCR_2-like	ADGRG5 VIPR2 ADGRL1 ADGRA1	1.15e-04	60	78	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRG5 VIPR2 ADGRL1 ADGRA1	1.23e-04	61	78	4	PS50261
Domain	Xpo1	IPO13 TNPO3	2.55e-04	6	78	2	PF08389
Domain	Exportin-1/Importin-b-like	IPO13 TNPO3	2.55e-04	6	78	2	IPR013598
Domain	GPCR_2_secretin-like_CS	VIPR2 ADGRL1 ADGRA1	3.82e-04	34	78	3	IPR017983
Domain	ARM-type_fold	CAND2 IPO13 ZYG11B LYST UNC79 TNPO3 HTT	5.34e-04	339	78	7	IPR016024
Domain	G_PROTEIN_RECEP_F2_1	ADGRG5 VIPR2 ADGRL1	6.19e-04	40	78	3	PS00649
Domain	GPCR_2_extracellular_dom	ADGRG5 VIPR2 ADGRL1	6.19e-04	40	78	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	ADGRG5 VIPR2 ADGRL1	6.19e-04	40	78	3	PS50227
Domain	Olfact_rcpt	OR51E2 OR2A14 OR51B5 OR10H3 OR51Q1 OR51B6 OR51B4	1.27e-03	393	78	7	IPR000725
Domain	Dynein_HC_stalk	DNHD1 DYNC1H1	1.52e-03	14	78	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC1H1	1.52e-03	14	78	2	IPR013602
Domain	DHC_N2	DNHD1 DYNC1H1	1.52e-03	14	78	2	PF08393
Domain	MT	DNHD1 DYNC1H1	1.52e-03	14	78	2	PF12777
Domain	ATPase_dyneun-rel_AAA	MDN1 DYNC1H1	1.52e-03	14	78	2	IPR011704
Domain	AAA_5	MDN1 DYNC1H1	1.52e-03	14	78	2	PF07728
Domain	DHC_fam	DNHD1 DYNC1H1	1.75e-03	15	78	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DYNC1H1	1.75e-03	15	78	2	IPR004273
Domain	Dynein_heavy	DNHD1 DYNC1H1	1.75e-03	15	78	2	PF03028
Domain	HEAT	CAND2 IPO13 HTT	1.83e-03	58	78	3	IPR000357
Domain	zf-C2H2_6	ZNF140 ZNF600 ZNF852 ZNF408 ZNF780B RREB1	2.00e-03	314	78	6	PF13912
Domain	PH_dom-like	PRKD3 ARHGEF40 FRMD7 MYLIP OBSCN PRKD1 LYST	2.01e-03	426	78	7	IPR011993
Domain	-	CAND2 IPO13 ZYG11B TNPO3 HTT	2.37e-03	222	78	5	1.25.10.10
Domain	HEAT_REPEAT	CAND2 IPO13 HTT	3.14e-03	70	78	3	PS50077
Domain	Ez/rad/moesin-like	FRMD7 MYLIP	3.43e-03	21	78	2	IPR000798
Domain	DAG/PE-bd	PRKD3 PRKD1	3.43e-03	21	78	2	IPR020454
Domain	HormR	VIPR2 ADGRL1	4.85e-03	25	78	2	SM00008
Domain	FERM_C	FRMD7 MYLIP	5.24e-03	26	78	2	PF09380
Domain	ARM-like	CAND2 IPO13 ZYG11B TNPO3 HTT	5.45e-03	270	78	5	IPR011989
Domain	FERM_C	FRMD7 MYLIP	5.65e-03	27	78	2	SM01196
Domain	FERM_PH-like_C	FRMD7 MYLIP	5.65e-03	27	78	2	IPR018980
Domain	-	PRKD3 ARHGEF40 FRMD7 MYLIP OBSCN PRKD1	5.86e-03	391	78	6	2.30.29.30
Domain	HRM	VIPR2 ADGRL1	6.07e-03	28	78	2	PF02793
Domain	zf-C2H2	ZNF140 ZNF600 ZNF852 ZNF408 ZNF780B ZKSCAN7 RREB1 ZNF687	8.24e-03	693	78	8	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF140 ZNF600 ZNF852 ZNF408 ZNF780B ZKSCAN7 RREB1 ZNF687	8.31e-03	694	78	8	IPR013087
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARHGEF40 IGF2R MDN1 SZT2 CTC1 ZNF408 OBSCN ADGRL1 DTX2 PLXND1 LYST TNPO3 DYNC1H1 TOP3A ZNF687 HTT	2.62e-09	1105	78	16	35748872
Pubmed	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.	OR51B5 OR51B6 OR51B4	4.84e-06	15	78	3	11121057
Pubmed	Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.	OR51B5 OR51B6 OR51B4	4.84e-06	15	78	3	10220430
Pubmed	Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.	PRKD3 PRKD1	1.49e-05	3	78	2	26253275
Pubmed	Expression of the protein kinase D (PKD) family during mouse embryogenesis.	PRKD3 PRKD1	1.49e-05	3	78	2	16377259
Pubmed	A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.	PRKD3 PRKD1	1.49e-05	3	78	2	27662904
Pubmed	Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.	PRKD3 PRKD1	1.49e-05	3	78	2	32747433
Pubmed	Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.	PRKD3 PRKD1	1.49e-05	3	78	2	26426580
Pubmed	A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation.	PRKD3 PRKD1	1.49e-05	3	78	2	20621130
Pubmed	Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.	OR51B5 OR51B6	1.49e-05	3	78	2	20018918
Pubmed	Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1(G93A) motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice.	GARS1 DYNC1H1	1.49e-05	3	78	2	19593442
Pubmed	Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.	PRKD3 PRKD1	1.49e-05	3	78	2	38419169
Pubmed	Huntingtin facilitates dynein/dynactin-mediated vesicle transport.	DYNC1H1 HTT	2.97e-05	4	78	2	17548833
Pubmed	Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.	PRKD3 PRKD1	2.97e-05	4	78	2	14743217
Pubmed	The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.	LYST HPS3	2.97e-05	4	78	2	23043085
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRG5 ADGRL1 ADGRA1	3.80e-05	29	78	3	15203201
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	IGF2R MDN1 GARS1 IPO13 FADS2 ZYG11B SLC39A10 TNPO3 WDTC1	4.85e-05	754	78	9	33060197
Pubmed	Protein kinase D regulates RhoA activity via rhotekin phosphorylation.	PRKD3 PRKD1	4.94e-05	5	78	2	22228765
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRG5 ADGRL1 ADGRA1	5.64e-05	33	78	3	25713288
Pubmed	Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.	DYNC1H1 HTT	7.40e-05	6	78	2	19525941
Pubmed	The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.	ZSWIM2 RNF133	7.40e-05	6	78	2	35831855
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR51E2 OR2A14 OR10H3 OR51Q1 OR51B6 OR51B4	1.19e-04	340	78	6	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR51E2 OR2A14 OR10H3 OR51Q1 OR51B6 OR51B4	1.19e-04	340	78	6	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR51E2 OR2A14 OR10H3 OR51Q1 OR51B6 OR51B4	1.25e-04	343	78	6	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR51E2 OR2A14 OR10H3 OR51Q1 OR51B6 OR51B4	1.31e-04	346	78	6	14611657
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PRKD3 IGF2R SLC26A2 FADS2 SLC39A10 LYST HPS3	1.40e-04	504	78	7	34432599
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CAND2 SUPT5H GARS1 IPO13 ZYG11B PRKD1 RREB1 TNPO3 DYNC1H1 DYRK2 WDTC1	1.72e-04	1321	78	11	27173435
Pubmed	Survival and lung pathology of mouse models of Hermansky-Pudlak syndrome and Chediak-Higashi syndrome.	LYST HPS3	1.77e-04	9	78	2	10193444
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAND2 SZT2 LRRC8A IPO13 PLXND1 FTO ZNF687	1.88e-04	529	78	7	14621295
Pubmed	Morphological diversity of single neurons in molecularly defined cell types.	VIPR2 PLXND1	2.21e-04	10	78	2	34616072
Pubmed	Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.	PRKD3 PRKD1	2.70e-04	11	78	2	2182321
Pubmed	In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence for the phosphorylation of amino acid residue serine-46.	PRKD3 PRKD1	2.70e-04	11	78	2	8914829
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ARHGAP32 PIEZO2 IGF2R SLC26A2 SLCO2B1 FRMD7 SLC39A10	2.93e-04	569	78	7	30639242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ADGRL1 ZYG11B SLC39A10 DYNC1H1 EPG5 EPM2AIP1	3.13e-04	407	78	6	12693553
Pubmed	HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta.	PRKD3 PRKD1	3.23e-04	12	78	2	11919157
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	ARHGAP32 TMTC1 MDN1 TNPO3 WDTC1	3.74e-04	272	78	5	18187620
Pubmed	Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.	NRBP2 SUPT5H	4.44e-04	14	78	2	22354037
Pubmed	Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.	LYST HPS3	5.12e-04	15	78	2	18715234
Pubmed	Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes.	PRKD3 PRKD1	5.12e-04	15	78	2	8627654
Pubmed	[HIV-1 Tat protein induces IL-10 production by human monocytes: implications of the PKC and calcium pathway].	PRKD3 PRKD1	5.84e-04	16	78	2	11833470
Pubmed	Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.	DNHD1 ARHGEF40	6.61e-04	17	78	2	12693554
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	IGF2R LRRC8A FADS2 SLC39A10	6.75e-04	176	78	4	28692057
Pubmed	Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.	SLC26A2 HTT	7.42e-04	18	78	2	9090377
Pubmed	Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.	PRKD1 FTO	7.42e-04	18	78	2	23669352
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	ADGRG5 ADGRL1 ADGRA1	7.59e-04	79	78	3	12679517
Pubmed	Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway.	PRKD3 PRKD1	9.19e-04	20	78	2	11044099
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PRKD3 PRKD1	1.01e-03	21	78	2	9446795
Pubmed	Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.	PRKD3 PRKD1	1.01e-03	21	78	2	9671211
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PRKD3 PRKD1	1.11e-03	22	78	2	11154208
Pubmed	Charcot-Marie-Tooth Neuropathy Type 2 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	GARS1 DYNC1H1	1.22e-03	23	78	2	20301462
Pubmed	Genomic variants in an inbred mouse model predict mania-like behaviors.	OBSCN HPS3	1.22e-03	23	78	2	29768498
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKD3 PRKD1	1.33e-03	24	78	2	10843712
Pubmed	Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.	PRKD3 SLCO2B1	1.33e-03	24	78	2	19706712
Pubmed	Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.	SFMBT1 LINS1 SLC39A10	1.42e-03	98	78	3	23898208
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 IGF2R MDN1 ADGRA1 PRKD1 UNC79 DYNC1H1 EPM2AIP1	1.42e-03	963	78	8	28671696
Pubmed	Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.	SLC26A2 HTT	1.44e-03	25	78	2	8889551
Pubmed	MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.	RREB1 TOP3A	1.44e-03	25	78	2	32528060
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ARHGAP32 IPO13 EPM2AIP1	1.54e-03	101	78	3	9872452
Pubmed	Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.	CAND2 TNPO3	1.56e-03	26	78	2	23181366
Pubmed	Role of phosphorylation in the nuclear biology of HIV-1.	PRKD1 TNPO3	1.68e-03	27	78	2	21651489
Cytoband	11p15.4	DNHD1 OR51B5 OR51Q1 OR51B6	3.88e-04	200	78	4	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51E2 DNHD1 OR51B5 OR51Q1 OR51B6 OR51B4	4.07e-04	564	78	6	chr11p15
GeneFamily	Olfactory receptors, family 51	OR51E2 OR51B5 OR51Q1 OR51B6 OR51B4	3.34e-07	44	60	5	164
GeneFamily	Armadillo repeat containing\|Importins	IPO13 TNPO3	1.60e-03	18	60	2	596
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CAND2 SLC10A7 FAM135B TOP3A SIAH3	2.85e-06	126	78	5	ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	TBXAS1 SLCO2B1 FADS2 HAS2 SLC10A7	1.30e-05	172	78	5	c477008444d2d71071177807870d7455e90c2fad
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP32 CAND2 PRKD1 DTX2 SLC10A7	1.33e-05	173	78	5	12f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBXAS1 CTC1 SLC26A2 SLCO2B1 MYLIP	1.45e-05	176	78	5	d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBXAS1 CTC1 SLC26A2 SLCO2B1 MYLIP	1.45e-05	176	78	5	4f37854124d77ee64dcb40fd491eaed2ba389891
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBXAS1 CTC1 SLC26A2 SLCO2B1 MYLIP	1.45e-05	176	78	5	0afba8707b847e5bdf6f38fe4379967631fe2240
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	PRKD3 SFMBT1 LYST DYNC1H1 EPG5	1.66e-05	181	78	5	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	Dendritic_cell\|World / shred by cell class for nasal brushing	TLR10 TBXAS1 ADGRG5 SLCO2B1 PLXND1	2.10e-05	190	78	5	ae24934f45eea9c228bf6fe8cd0d6abca9eb208e
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FADS2 PRKD1 HAS2	2.10e-05	190	78	5	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FADS2 PRKD1 HAS2	2.15e-05	191	78	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FADS2 PRKD1 HAS2	2.20e-05	192	78	5	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
Computational	Genes in the cancer module 239.	IGF2R LRRC8A FADS2 PLXND1 DYNC1H1	9.75e-05	120	42	5	MODULE_239
Disease	Thromboembolism	OR51E2 OR51B5 FAM135B	1.72e-04	44	72	3	HP_0001907
Disease	anti-topoisomerase-I-antibody-positive systemic scleroderma	TLR10 TNPO3	2.61e-04	10	72	2	EFO_0008537
Disease	triacylglycerol 54:9 measurement	TMTC1 FADS2	3.81e-04	12	72	2	EFO_0010427
Disease	fatty acid measurement, fetal genotype effect measurement, breast milk measurement	FADS2 FAM135B	4.50e-04	13	72	2	EFO_0005110, EFO_0007959, EFO_0009092
Disease	fatty acid measurement, breast milk measurement, parental genotype effect measurement	FADS2 FAM135B	5.24e-04	14	72	2	EFO_0005110, EFO_0005939, EFO_0009092
Disease	platelet storage pool deficiency (implicated_via_orthology)	LYST HPS3	6.04e-04	15	72	2	DOID:2223 (implicated_via_orthology)
Disease	P wave duration	CAND2 FADS2	6.04e-04	15	72	2	EFO_0005094
Disease	diabetes mellitus	ANO4 FTO RREB1	6.23e-04	68	72	3	EFO_0000400
Disease	phosphatidylcholine 38:3 measurement	IGF2R FADS2	6.89e-04	16	72	2	EFO_0010385
Disease	Mood Disorders	CACNA1D FTO CRHBP HTT	7.72e-04	168	72	4	C0525045
Disease	Charcot-Marie-Tooth disease type 2	GARS1 DYNC1H1	7.80e-04	17	72	2	cv:C0270914
Disease	fetal hemoglobin measurement	OR51B5 OR51B6	1.20e-03	21	72	2	EFO_0004576
Disease	sleep duration, low density lipoprotein cholesterol measurement	IGF2R FADS2 HTT	1.45e-03	91	72	3	EFO_0004611, EFO_0005271
Disease	lysophosphatidylcholine 18:0 measurement	TMTC1 FADS2	1.57e-03	24	72	2	EFO_0010359
Disease	systemic mastocytosis	OR51B5 OR51Q1	1.70e-03	25	72	2	MONDO_0016586

Protein segments in the cluster

Peptide	Gene	Start	Entry
FHQLVALLHCRSLHK	TTYH1	361	Q9H313
LKNEQFLSHLLLFLH	EPG5	1076	Q9HCE0
KCLRHVFLFEHLLLF	ARHGEF40	1286	Q8TER5
HLGQSRLFLLCHKEA	CTC1	726	Q2NKJ3
VFIFVFHCALQKKVH	ADGRL1	1091	O94910
KGRHTLLNFCFHAAL	ADGRA1	51	Q86SQ6
TLQHPAKLRFLHCIF	AADACL4	36	Q5VUY2
KLLFHNAALLHLVRT	ATP8B3	541	O60423
VCSHLHLFFLIGDKQ	DNHD1	3006	Q96M86
AFIIVFEHLVFCIKH	ANO4	886	Q32M45
CSHSHFVRLFQKQLL	CDAN1	496	Q8IWY9
EIISFQHLHRLTCLK	LRRC8A	631	Q8IWT6
FKTNHVFFLLLLAHI	FADS2	126	O95864
ALVHLKLHLFIQIFT	SLC10A7	66	Q0GE19
HEINHFFCEILSVLK	OR2A14	171	Q96R47
LVALRHLHFKNIVHC	PRKD1	691	Q15139
KELLCQLLTSLHHFV	MDN1	3191	Q9NU22
LFEVHSLKLLAAHCF	NRBP2	306	Q9NSY0
ASRIHLKLHFTCQRI	LINS1	261	Q8NG48
LCFPQRLKNFHVLSH	NLRP8	521	Q86W28
HLTKCSHAFHLLCLL	DTX2	441	Q86UW9
QEAFLTLHKHGCLFR	FTO	66	Q9C0B1
KHFLIKLHANILVLC	FRMD7	236	Q6ZUT3
LLHRVAFLDHLCKQK	C9orf131	81	Q5VYM1
LLNNKHFLIVFVHAL	PLXND1	1416	Q9Y4D7
LLHTFCLHQDVIKLA	OR51B4	171	Q9Y5P0
VLSHAFCLHQDVIKL	OR51B5	171	Q9H339
VLSHAFCLHQDVIKL	OR51B6	171	Q9H340
LIKRLAFCHSNVLSH	OR51E2	161	Q9H255
SLFLLKRLPFCHSHL	OR51Q1	161	Q8NH59
ALRNLHFKNIVHCDL	PRKD3	686	O94806
QTRHIFFLHIKEALL	MYLIP	91	Q8WY64
KHLHLCIYDRRFSQL	ARHGAP32	181	A7KAX9
HHFLCHVLSLLKLAC	OR10H3	176	O60404
HVFLFRNHLVICKPR	OBSCN	5921	Q5VST9
LFSHLLKVINICAHV	HTT	1141	P42858
KLQCHFILIFLTALR	CRHBP	6	P24387
HICTFEVKLNLFQRH	EPM2AIP1	411	Q7L775
HLIIQSLFAFLEHRK	HAS2	56	Q92819
LRKFHITNHACLVLA	CARD19	101	Q96LW7
IANNLLFKCHIHLRI	CEP95	11	Q96GE4
QLLKAQVVHHFLLTC	LYST	1956	Q99698
KKLHSLQPHACFRLF	DYNC1H1	4111	Q14204
AKDCTLIRHNVFHAL	FAM135B	1356	Q49AJ0
LHKQVFHSLARCVAA	CAND2	796	O75155
HTKFCLICLLTFIFH	SLC39A10	6	Q9ULF5
RKFAHSILQCLDALH	DYRK2	326	Q92630
ADILFALNKHCFSLL	IPO13	886	O94829
KLINHHIFTNLILVF	CACNA1D	881	Q01668
KKHFFINICHRVLQE	IGF2R	511	P11717
LIFCLLSQKLGLFHH	SZT2	2691	Q5T011
NDIVRILTCKHFFHK	RNF133	266	Q8WVZ7
KIAHLHLNTVFLGFR	TLR10	161	Q9BXR5
LFIGLKAICHFKNHI	HPS3	431	Q969F9
CFRADHLLKAHLQKL	GARS1	211	P41250
SCLGHHFLLVLRKQE	SIAH3	161	Q8IW03
HLFRSFAFLHCKKLV	SUPT5H	616	O00267
VASLITVLLHFHFRK	ADGRG5	261	Q8IZF4
LTLLHVLHKFRFQAC	TBXAS1	491	P24557
ISLNPCHLKAHFRLA	WDTC1	426	Q8N5D0
VAFRKAFCHHKLVEL	ZYG11B	96	Q9C0D3
LLSLHCLAAFKRLEH	TMTC1	366	Q8IUR5
SAAFAAKRNCIHHIL	RREB1	796	Q92766
IHVFRNIHKTNLCDL	SLC26A2	291	P50443
HNIKLFVLCHSLLQL	SLCO2B1	46	O94956
AFLQLCHLKKHAFVH	ZNF408	361	Q9H9D4
IQLLALFFHRSILKC	PIEZO2	2021	Q9H5I5
CGKAFRLHLQLSLHQ	ZNF780B	786	Q9Y6R6
KRHRLFNHTACLVLY	TOP3A	286	Q13472
FRKLHCTRNYIHLNL	VIPR2	151	P41587
KAYIQRLLHALARHC	TNPO3	366	Q9Y5L0
LCLKAFHLGQHTRLL	ZSWIM2	346	Q8NEG5
AFGLSKCLIRHQRLH	ZNF852	391	Q6ZMS4
KAFRCHSFLIKHQRI	ZNF140	336	P52738
FGLSKCLIRHQRLHT	ZKSCAN7	616	Q9P0L1
VFFNKCSLLLHAREH	ZNF687	571	Q8N1G0
AIKLCHHIERIKFAF	SFMBT1	846	Q9UHJ3
FNCSSLLRKHQIPHL	ZNF600	171	Q6ZNG1
CRFLDIHSVTKNHLL	UNC79	1071	Q9P2D8
HICVVLFKLFHVCLF	PP6455	96	Q8WZ26