Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	BRK	CHD8 CHD7	2.12e-04	6	71	2	SM00592
Domain	BRK_domain	CHD8 CHD7	2.12e-04	6	71	2	IPR006576
Domain	BRK	CHD8 CHD7	2.12e-04	6	71	2	PF07533
Domain	Helicase_C	DDX54 CHD8 CHD7 DICER1	7.37e-04	107	71	4	PF00271
Domain	HELICc	DDX54 CHD8 CHD7 DICER1	7.37e-04	107	71	4	SM00490
Domain	Helicase_C	DDX54 CHD8 CHD7 DICER1	7.63e-04	108	71	4	IPR001650
Domain	HELICASE_CTER	DDX54 CHD8 CHD7 DICER1	7.90e-04	109	71	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX54 CHD8 CHD7 DICER1	7.90e-04	109	71	4	PS51192
Domain	Cadherin_CS	FAT4 CELSR2 PCDHB14 PCDH8	7.90e-04	109	71	4	IPR020894
Domain	DEXDc	DDX54 CHD8 CHD7 DICER1	7.90e-04	109	71	4	SM00487
Domain	Helicase_ATP-bd	DDX54 CHD8 CHD7 DICER1	8.17e-04	110	71	4	IPR014001
Domain	CADHERIN_1	FAT4 CELSR2 PCDHB14 PCDH8	9.04e-04	113	71	4	PS00232
Domain	Cadherin	FAT4 CELSR2 PCDHB14 PCDH8	9.04e-04	113	71	4	PF00028
Domain	CADHERIN_2	FAT4 CELSR2 PCDHB14 PCDH8	9.34e-04	114	71	4	PS50268
Domain	-	FAT4 CELSR2 PCDHB14 PCDH8	9.34e-04	114	71	4	2.60.40.60
Domain	CA	FAT4 CELSR2 PCDHB14 PCDH8	9.65e-04	115	71	4	SM00112
Domain	Cadherin-like	FAT4 CELSR2 PCDHB14 PCDH8	9.96e-04	116	71	4	IPR015919
Domain	Cadherin	FAT4 CELSR2 PCDHB14 PCDH8	1.06e-03	118	71	4	IPR002126
Domain	P-loop_NTPase	NPHP3 CHST15 KIF19 DDX54 CHD8 IFI44L CHD7 KIF5A PFKFB3 DICER1	1.32e-03	848	71	10	IPR027417
Domain	PDZ	SHANK1 MAST4 FRMPD4 FRMPD3	2.04e-03	141	71	4	PF00595
Domain	PDZ	SHANK1 MAST4 FRMPD4 FRMPD3	2.44e-03	148	71	4	SM00228
Domain	-	SHANK1 MAST4 FRMPD4 FRMPD3	2.56e-03	150	71	4	2.30.42.10
Domain	His_PPase_superfam	ACP4 PFKFB3	2.59e-03	20	71	2	IPR029033
Domain	-	ACP4 PFKFB3	2.59e-03	20	71	2	3.40.50.1240
Domain	PDZ	SHANK1 MAST4 FRMPD4 FRMPD3	2.62e-03	151	71	4	PS50106
Domain	PDZ	SHANK1 MAST4 FRMPD4 FRMPD3	2.68e-03	152	71	4	IPR001478
Domain	Chromo_domain	CHD8 CHD7	3.73e-03	24	71	2	IPR023780
Domain	Bromodomain_CS	PHIP BRWD1	4.37e-03	26	71	2	IPR018359
Domain	Chromo	CHD8 CHD7	4.37e-03	26	71	2	PF00385
Domain	CHROMO_1	CHD8 CHD7	5.05e-03	28	71	2	PS00598
Domain	hEGF	FAT4 CELSR2	5.05e-03	28	71	2	PF12661
Domain	CHROMO_2	CHD8 CHD7	5.05e-03	28	71	2	PS50013
Domain	Ubiquitin-rel_dom	FRMPD4 RAPGEF5 FRMPD3 APBB1IP	5.30e-03	184	71	4	IPR029071
Domain	ASX_HYDROXYL	FAT4 CELSR2 LRP1	6.54e-03	100	71	3	PS00010
Domain	SNF2_N	CHD8 CHD7	6.57e-03	32	71	2	IPR000330
Domain	JMJC	TYW5 KDM2B	6.57e-03	32	71	2	PS51184
Domain	Chromodomain-like	CHD8 CHD7	6.57e-03	32	71	2	IPR016197
Domain	SNF2_N	CHD8 CHD7	6.57e-03	32	71	2	PF00176
Domain	JmjC_dom	TYW5 KDM2B	6.57e-03	32	71	2	IPR003347
Domain	JmjC	TYW5 KDM2B	6.97e-03	33	71	2	SM00558
Domain	Chromo/shadow_dom	CHD8 CHD7	6.97e-03	33	71	2	IPR000953
Domain	CHROMO	CHD8 CHD7	6.97e-03	33	71	2	SM00298
Domain	-	NPHP3 CHST15 DDX54 CHD8 IFI44L CHD7 PFKFB3 DICER1	7.22e-03	746	71	8	3.40.50.300
Domain	MAGE	MAGED1 TRO	7.39e-03	34	71	2	SM01373
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 PTPN9 CSNK1A1L SF3B1 MAGED1 CELSR2 CLTC LRP1 CHD8 CHD7 KIF5A FRMPD3 PCDH8	1.34e-07	963	75	13	28671696
Pubmed	CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome.	CHD8 CHD7	4.59e-06	2	75	2	20453063
Pubmed	Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.	CHD8 CHD7	4.59e-06	2	75	2	24211491
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PTPN9 CSNK1A1L VPS26B SHCBP1 LRRC1 DDX54 LRP1 KRI1 KIF5A ELP3 DICER1	7.50e-06	974	75	11	28675297
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM15 SF3B1 CLTC DDX54 KRI1 CHD8 CHD7 DICER1 PHIP	1.14e-05	653	75	9	22586326
Pubmed	Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8.	CHD8 CHD7	1.37e-05	3	75	2	30108144
Pubmed	Comparative expression analysis of the MAGED genes during embryogenesis and brain development.	MAGED1 TRO	1.37e-05	3	75	2	15162511
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD7	1.37e-05	3	75	2	28533432
Pubmed	Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes.	CHD8 CHD7	1.37e-05	3	75	2	30277262
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	1.37e-05	3	75	2	24220028
Pubmed	Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.	CHD8 CHD7	2.75e-05	4	75	2	23285124
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD4 GSE1 CHST15 RAPGEF5 TRO VPS8 CLTC	2.86e-05	407	75	7	12693553
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SEC16B RBM15 SF3B1 GSE1 SHCBP1 CLTC SORBS3 KDM2B CHD7	4.33e-05	774	75	9	15302935
Pubmed	Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.	RBM15 SF3B1	4.57e-05	5	75	2	26575292
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1A1L CSNK1G1	6.84e-05	6	75	2	16014721
Pubmed	CHARGE and Kabuki syndromes: a phenotypic and molecular link.	CHD8 CHD7	6.84e-05	6	75	2	24705355
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RBM15 PTPN9 GSE1 COPE LRRC1 CLTC SORBS3 DDX54 KRI1 ELP3	8.38e-05	1049	75	10	27880917
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	RBM15 SF3B1 MAGED1 TRO CLTC DDX54 KRI1 MRPL1	1.07e-04	678	75	8	30209976
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	SHANK1 FAT4 SF3B1 FRMPD4 CLTC KDM2B PFKFB3	1.22e-04	513	75	7	25798074
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SF3B1 CELSR2 KRI1 CHD7 MNAT1 PHIP	1.26e-04	358	75	6	32460013
Pubmed	Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.	SUPT20HL1 SUPT20HL2	1.27e-04	8	75	2	21802298
Pubmed	Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.	SHCBP1 CENPI PHIP	1.46e-04	47	75	3	15009096
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	RBM15 SF3B1 CLTC DDX54 KRI1	1.55e-04	234	75	5	36243803
Pubmed	Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.	CLTC LRP1	2.04e-04	10	75	2	26005850
Pubmed	Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7.	CSNK1A1L CSNK1G1	2.04e-04	10	75	2	25500533
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RBM15 SF3B1 MAGED1 COPE DDX54 LRP1 KRI1 PFKFB3 MRPL1	2.40e-04	971	75	9	33306668
Pubmed	Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.	SUPT20HL1 SUPT20HL2	2.49e-04	11	75	2	24051374
Pubmed	The DNA sequence of the human X chromosome.	SUPT20HL1 MAGED1 TRO CENPI SUPT20HL2 FRMPD3	2.52e-04	407	75	6	15772651
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SF3B1 MAGED1 COPE VPS8 CLTC DDX54 KRI1 IFI44L PFKFB3 DICER1 MRPL1	2.53e-04	1440	75	11	30833792
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SHANK1 CA12 P4HA2 SF3B1 MAGED1 GSE1 CENPI CLTC LRP1 CHD8	2.54e-04	1203	75	10	29180619
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PIKFYVE RBM15 MAGED1 GSE1 CLTC KDM2B CHD7	2.80e-04	588	75	7	38580884
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	SHANK1 CHD8	2.99e-04	12	75	2	27824329
Pubmed	Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.	P4HA2 SF3B1 MAGED1 CLTC	3.27e-04	151	75	4	18457437
Pubmed	Protocadherins.	PCDHB14 PCDH8	3.52e-04	13	75	2	12231349
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	RBM15 SHCBP1 CHD8 CHD7 MRPL1	3.67e-04	282	75	5	23667531
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM2B CHD8 CHD7 METTL14	3.79e-04	157	75	4	30186101
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	FAT4 CELSR2 RYK	4.18e-04	67	75	3	21875946
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 SF3B1 MAGED1 ARIH2 CLTC LRP1 CCDC15 KIF5A MNAT1 BRWD1	4.28e-04	1285	75	10	35914814
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	SUPT20HL1 TRADD RBM15 SUPT20HL2 MNAT1 METTL14	4.67e-04	457	75	6	32968282
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	CELSR2 PCDHB14 PCDH8	5.16e-04	72	75	3	10380929
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RBM15 SF3B1 GSE1 CLTC DDX54 KRI1 CHD8 CHD7 PHIP MRPL1	5.22e-04	1318	75	10	30463901
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	RBM15 SF3B1 TYW5 COPE DDX54 KRI1 ELP3	5.24e-04	653	75	7	33742100
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	RSPH3 CHD7 PHIP RYK BRWD1	5.32e-04	306	75	5	18973680
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CSNK1A1L SF3B1 MAGED1 SHCBP1 ARIH2 LRRC1 CLTC ELP3 DICER1 MRPL1	5.76e-04	1335	75	10	29229926
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	CELSR2 PCDHB14 PCDH8	6.28e-04	77	75	3	10835267
Pubmed	An overview of the MAGE gene family with the identification of all human members of the family.	MAGED1 TRO	6.87e-04	18	75	2	11454705
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	CELSR2 PCDHB14 PCDH8	7.02e-04	80	75	3	10716726
Pubmed	The Role of Sorting Nexin 17 in Cardiac Development.	FAT4 LRP1	7.66e-04	19	75	2	34988124
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	GSE1 KDM2B CHD7	7.82e-04	83	75	3	28794006
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	MAGED1 GSE1 KDM2B CHD8 MNAT1	8.44e-04	339	75	5	30415952
Pubmed	Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development.	MAST4 CLTC	8.50e-04	20	75	2	25196998
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	RBM15 CSNK1A1L SF3B1 CLTC MNAT1	8.55e-04	340	75	5	24332808
Pubmed	The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.	PIKFYVE CSNK1A1L CLTC	8.67e-04	86	75	3	26885983
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SHANK1 FRMPD4 CSNK1G1 PYGM	8.87e-04	197	75	4	36604605
Pubmed	Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.	SUPT20HL1 SUPT20HL2	9.38e-04	21	75	2	23747598
Pubmed	Supt20 is required for development of the axial skeleton.	SUPT20HL1 SUPT20HL2	9.38e-04	21	75	2	27894818
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	SUPT20HL1 SUPT20HL2	1.03e-03	22	75	2	16751104
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15 SF3B1 CLTC KRI1 CHD8 CHD7 PHIP MRPL1	1.04e-03	954	75	8	36373674
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	PSME3IP1 SF3B1 CLTC DDX54 CHD8	1.06e-03	357	75	5	37059091
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	VPS8 LRP1	1.23e-03	24	75	2	17452356
Pubmed	Genomic screen for genes involved in mammalian craniofacial development.	MAGED1 TRO	1.23e-03	24	75	2	12533789
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	GSE1 KDM2B	1.23e-03	24	75	2	33722704
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	SF3B1 CHD8	1.33e-03	25	75	2	15456888
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	SNX30 SORBS3	1.33e-03	25	75	2	16374509
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	SPATA2L P4HA2 RBM15 UCHL3 SHCBP1 LRP1 KRI1 DICER1	1.44e-03	1005	75	8	19615732
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PSME3IP1 RBM15 SF3B1 UCHL3 ARIH2 CHD8 MNAT1 METTL14	1.53e-03	1014	75	8	32416067
Pubmed	Same but different - Molecular comparison of human KTI12 and PSTK.	MAGED1 ELP3	1.56e-03	27	75	2	33417976
Pubmed	Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons.	RAPGEF5 RYK	1.56e-03	27	75	2	31257105
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	RBM15 SF3B1 LRRC1 CHD8 CHD7 APBB1IP	1.62e-03	582	75	6	20467437
Pubmed	TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.	SF3B1 CLTC	1.67e-03	28	75	2	29653964
Pubmed	The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.	SUPT20HL1 SUPT20HL2	1.67e-03	28	75	2	19114550
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	CHD8 CHD7 PHIP	1.72e-03	109	75	3	33554859
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	MAGED1 GSE1 SORBS3 PYGM APBB1IP	1.79e-03	402	75	5	24722188
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	PHIP BRWD1	1.79e-03	29	75	2	21834987
Pubmed	Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.	DICER1 BRWD1	1.79e-03	29	75	2	31330130
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CELSR2 LRP1	1.79e-03	29	75	2	20167577
Pubmed	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.	SUPT20HL1 SUPT20HL2	1.92e-03	30	75	2	18206972
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SHCBP1 DDX54 KRI1 CHD8 CHD7	1.95e-03	410	75	5	26949251
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DDX54 KDM2B CHD8 CHD7 PHIP BRWD1	2.02e-03	608	75	6	36089195
Pubmed	The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling.	SHCBP1 DICER1	2.05e-03	31	75	2	22508726
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	SF3B1 MAGED1 VPS26B CLTC SORBS3	2.12e-03	418	75	5	32552912
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GSE1 LRP1 KDM2B CHD8 CHD7	2.12e-03	418	75	5	34709266
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	PIKFYVE CENPI VPS8 ELP3	2.16e-03	251	75	4	29778605
Interaction	CENPA interactions	SHCBP1 CENPI DDX54 KDM2B KRI1 CHD7 ELP3 PHIP BRWD1	9.65e-06	377	74	9	int:CENPA
GeneFamily	PDZ domain containing	SHANK1 MAST4 FRMPD4 FRMPD3	4.19e-04	152	42	4	1220
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	PHIP BRWD1	7.87e-04	18	42	2	498
GeneFamily	MAGE family	MAGED1 TRO	3.89e-03	40	42	2	1136
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF19 KIF5A	5.11e-03	46	42	2	622
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD4 FRMPD3	6.01e-03	50	42	2	1293
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	P4HA2 MAGED1 CHST15 VPS26B SORBS3 APBB1IP	8.54e-07	191	75	6	054fa0493b00149313c243d39cf39a264044f074
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 MAST4 CHST15 RAPGEF5 CHD7 BRWD1	1.12e-06	200	75	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	AOC3 CCDC15 ACP4 FRMPD3 MNAT1	4.67e-06	145	75	5	34fc6da04d4fe0817e37cdcd844fe2a6e53a4796
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; PC3; HT_HG-U133A	IPPK CA12 CELSR2 ARIH2 DDX54 KRI1 RYK	3.39e-06	198	73	7	6346_DN
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD7	1.29e-04	7	74	2	DOID:0050834 (implicated_via_orthology)
Disease	Major Depressive Disorder	RAPGEF5 LRP1 IFI44L HTR3B PFKFB3	3.69e-04	243	74	5	C1269683
Disease	Oligospermia	DICER1 BRWD1	4.03e-04	12	74	2	C0028960
Disease	cyclic adenosine monophosphate measurement	MAST4 NT5C1B	8.24e-04	17	74	2	EFO_0010473
Disease	cytotoxicity measurement, response to clozapine	SHANK1 CHST15	2.41e-03	29	74	2	EFO_0006952, GO_0097338

Protein segments in the cluster

Peptide	Gene	Start	Entry
YVNARLRDLYPDEQD	NT5C1B	361	Q96P26
EDYLIQRRYLYERID	CHD8	1166	Q9HCK8
NEFVDIERYPDLPYV	HTR3B	121	O95264
DPAYIYDEFLQQRRR	GSE1	721	Q14687
PDIIERENPYLIYDE	FAT4	4581	Q6V0I7
LYEIYPELQIERFFE	APBB1IP	221	Q7Z5R6
PRIPESLRRFYEDYQ	SPATA5	871	Q8NB90
PERDVERDVFLYRAY	COPE	46	O14579
LPNEELREKYRRYLF	ARIH2	201	O95376
LVDLDYEDRPEYVLV	CELSR2	981	Q9HCU4
DYQDAVIIPRYRNFD	DICER1	926	Q9UPY3
ILEDYLIQRRYPYER	CHD7	1321	Q9P2D1
YHRRPVLFQEYLDID	AOC3	166	Q16853
DLERERDYPFYERVR	RBM15	326	Q96T37
EGLYPLYNRVERYLE	IPPK	336	Q9H8X2
LYNRVERYLEEFPEE	IPPK	341	Q9H8X2
QGIYEEYEDIRRENP	PTPN9	301	P43378
EAVALDYEARRPIYE	PAQR7	291	Q86WK9
IYNKREEDFPSLREY	MNAT1	81	P51948
IIREYTDVYPEIIER	MAGED1	501	Q9Y5V3
EPRYLVVYNPLEQDR	MAN2A1	646	Q16706
DEEPFLIFANRYYLR	LRP1	3026	Q07954
FDVILLEPPLEEYYR	METTL14	186	Q9HCE5
LLADIRDYRPYADLV	IFI44L	181	Q53G44
RDYRPYADLVSEIRI	IFI44L	186	Q53G44
RYVRRLDFFEKPDYE	CSNK1G1	291	Q9HCP0
EEARQRDQEFYIPYR	DDX54	671	Q8TDD1
NIEELLPERTAEYYR	CA12	206	O43570
PVDYERQDTYELDVR	PCDH8	311	O95206
EIRDTYPEEYALREQ	PFKFB3	336	Q16875
EYYRLDYEDIIDDLP	KRI1	506	Q8N9T8
LRFEEVPDYMYLRQL	CSNK1A1L	266	Q8N752
YVPEEIYRYARSLEE	LRRC1	26	Q9BTT6
IYERPVDYLPERDVY	P4HA2	276	O15460
VDYLPERDVYESLCR	P4HA2	281	O15460
PQRLEELYEVYLREL	KIF19	626	Q2TAC6
AFLSPEYRREEVYIR	ACP4	91	Q9BZG2
YPELVLDRALDYEQE	PCDHB14	191	Q9Y5E9
DQLFRDEYALYRPLQ	PIKFYVE	426	Q9Y2I7
DFNYEYVQREALRVP	KDM2B	91	Q8NHM5
VELLRRDPAAFEYLY	FRMPD3	271	Q5JV73
DLLRRDPVAFEYLYV	FRMPD4	296	Q14CM0
PVDLVEYPDYRDIID	BRWD1	1341	Q9NSI6
ALPEEYRDYFIRNLH	ELP3	176	Q9H9T3
RLLECLEFDPEEFYY	MAST4	481	O15021
YYRENDVPRRLEELL	ENO4	26	A6NNW6
PEERQKYEEEIRRLY	KIF5A	411	Q12840
KRLGYRYIEEPLEEA	FAM187B	161	Q17R55
INCVRDEPVLLRFYY	CENPI	376	Q92674
DEVRRLIGLDAELYY	RYK	71	P34925
YRAPLDLYRDLQEDE	SPATA2L	221	Q8IUW3
ETIRLPYEERALLDY	SUPT20HL1	101	Q3ZLR7
PRQDYIFYLEPERLE	SEMA3F	181	Q13275
YEREGLYEQAFQLLR	TRADD	256	Q15628
VPELEYAAAEYERLR	NPHP3	81	Q7Z494
EEVYDPRSLYERLQE	PSME3IP1	46	Q9GZU8
YRNVLDDVYEYPILE	RAPGEF5	176	Q92565
YLRDPLREEEVFNYI	VPS8	926	Q8N3P4
EYDYFVRCVEPRLRL	SHCBP1	216	Q8NEM2
FLEEERLLREYPQSF	SHANK1	131	Q9Y566
ETIRLPYEERALLDY	SUPT20HL2	101	P0C7V6
ERVREELPLDYHQYV	CCDC15	686	Q0P6D6
ERFLRENPYYDSRVV	CLTC	891	Q00610
DRYPVEDYLDLFDLA	CHST15	306	Q7LFX5
EIYVDPEREIYKRLG	PRXL2C	116	Q7RTV5
EPEDDVYLKRLYPRQ	MRPL1	81	Q9BYD6
YLNLVLIDEEERRYF	VPS26B	271	Q4G0F5
YFYDPIERDIEIGFL	RSPH3	421	Q86UC2
PEERARYLENYDAIR	UCHL3	131	P15374
FRQPVDLLEYPDYRD	PHIP	1341	Q8WWQ0
EYYDRIPELRQVIEQ	PYGM	731	P11217
EFDLPEYSVRRRYQD	SNX30	121	Q5VWJ9
LRDVIQEYDEYFPEI	TRO	471	Q12816
VVIEPLLIDEDYYAR	SF3B1	576	O75533
LLIDEDYYARVEGRE	SF3B1	581	O75533
RRRVSLVLPEYYEAF	SPDYE3	236	A6NKU9
EYYEAFNRLLEDPVI	SPDYE3	391	A6NKU9
YQYRPQNEDELELRE	SORBS3	621	O60504
YELSQYIRDAPERDD	SEC16B	236	Q96JE7
ELRLQPYREIFEFFI	TSNAXIP1	71	Q2TAA8
LAELPEEYRDFYARR	TYW5	286	A2RUC4