Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionKrueppel-associated box domain binding

HDAC1 HDAC2

2.48e-053582GO:0035851
GeneOntologyMolecularFunctionhistone reader activity

ZCWPW1 PHF14 TP53BP1

5.77e-0526583GO:0140566
GeneOntologyMolecularFunctionprotein decrotonylase activity

HDAC1 HDAC2

8.25e-055582GO:0160008
GeneOntologyMolecularFunctionhistone decrotonylase activity

HDAC1 HDAC2

8.25e-055582GO:0160009
GeneOntologyMolecularFunctionNF-kappaB binding

AKAP8 HDAC1 HDAC2

1.55e-0436583GO:0051059
GeneOntologyMolecularFunctionchromatin-protein adaptor activity

ZCWPW1 PHF14 TP53BP1

2.29e-0441583GO:0140463
GeneOntologyMolecularFunctiontropomyosin binding

CALD1 TNNT1

8.50e-0415582GO:0005523
GeneOntologyMolecularFunctionnucleosomal DNA binding

HMGN5 HDAC1 HDAC2

9.76e-0467583GO:0031492
GeneOntologyMolecularFunctionhistone binding

PTMS ZCWPW1 PHF14 TP53BP1 HDAC2

1.02e-03265585GO:0042393
GeneOntologyBiologicalProcessfungiform papilla formation

HDAC1 HDAC2

4.65e-054582GO:0061198
GeneOntologyBiologicalProcessnegative regulation of stem cell population maintenance

ARID4B HDAC1 HDAC2

5.24e-0526583GO:1902455
GeneOntologyBiologicalProcessRNA splicing

DHX16 RBM25 C9orf78 SF3A1 DHX38 PRPF38B RBM28 IWS1

7.66e-05502588GO:0008380
GeneOntologyBiologicalProcesshair follicle placode formation

HDAC1 HDAC2

1.16e-046582GO:0060789
GeneOntologyBiologicalProcessfungiform papilla morphogenesis

HDAC1 HDAC2

1.16e-046582GO:0061197
GeneOntologyBiologicalProcessmRNA processing

DHX16 RBM25 C9orf78 SF3A1 DHX38 PRPF38B RBM28 IWS1

1.46e-04551588GO:0006397
GeneOntologyBiologicalProcessfungiform papilla development

HDAC1 HDAC2

1.62e-047582GO:0061196
GeneOntologyCellularComponentSin3-type complex

ARID4B HDAC1 HDAC2

3.33e-0522603GO:0070822
GeneOntologyCellularComponentspliceosomal complex

DHX16 C9orf78 SF3A1 DHX38 PRPF38B RBM28

3.48e-05215606GO:0005681
GeneOntologyCellularComponentprecatalytic spliceosome

DHX16 SF3A1 PRPF38B

5.02e-0454603GO:0071011
DomainHis_deacetylse_1

HDAC1 HDAC2

5.66e-054582IPR003084
DomainHist_deacetyl

HDAC1 HDAC2

5.12e-0411582PF00850
DomainHis_deacetylse_dom

HDAC1 HDAC2

5.12e-0411582IPR023801
Domain-

HDAC1 HDAC2

5.12e-04115823.40.800.20
DomainHis_deacetylse

HDAC1 HDAC2

5.12e-0411582IPR000286
DomainDUF1605

DHX16 DHX38

1.25e-0317582IPR011709
DomainOB_NTP_bind

DHX16 DHX38

1.25e-0317582PF07717
DomainHA2

DHX16 DHX38

1.40e-0318582SM00847
DomainHA2

DHX16 DHX38

1.40e-0318582PF04408
DomainHelicase-assoc_dom

DHX16 DHX38

1.40e-0318582IPR007502
DomainDNA/RNA_helicase_DEAH_CS

DHX16 DHX38

5.28e-0335582IPR002464
DomainDEAH_ATP_HELICASE

DHX16 DHX38

6.20e-0338582PS00690
DomainUBQ

NEDD8 SF3A1

7.89e-0343582SM00213
Domainubiquitin

NEDD8 SF3A1

9.37e-0347582PF00240
DomainUBIQUITIN_2

NEDD8 SF3A1

1.22e-0254582PS50053
PathwayKEGG_SPLICEOSOME

DHX16 RBM25 SF3A1 DHX38 PRPF38B

4.01e-05127435M2044
PathwayWP_HISTONE_MODIFICATIONS

HDAC1 HDAC2

9.04e-055432MM15874
PathwayREACTOME_P75NTR_NEGATIVELY_REGULATES_CELL_CYCLE_VIA_SC1

HDAC1 HDAC2

1.35e-046432M27072
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION

HDAC1 HDAC2

1.89e-047432M47673
PathwayREACTOME_METABOLISM_OF_RNA

DHX16 RBM25 UPF2 C9orf78 SF3A1 PSMA4 DHX38 PSMD7 RBM28

2.76e-04724439M16843
PathwayREACTOME_MRNA_SPLICING

DHX16 RBM25 C9orf78 SF3A1 DHX38

3.47e-04201435MM15411
PathwayREACTOME_MRNA_SPLICING

DHX16 RBM25 C9orf78 SF3A1 DHX38

4.44e-04212435M14033
PathwayREACTOME_METABOLISM_OF_RNA

DHX16 RBM25 UPF2 C9orf78 SF3A1 PSMA4 DHX38 PSMD7

4.55e-04612438MM15547
PathwayKEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION

HDAC1 HDAC2

4.91e-0411432M47438
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

HDAC1 HDAC2

4.91e-0411432M42523
PathwayBIOCARTA_PRC2_PATHWAY

HDAC1 HDAC2

8.08e-0414432M22025
PathwayREACTOME_PTEN_REGULATION

PSMA4 PSMD7 HDAC1 HDAC2

8.29e-04139434M27646
PathwayREACTOME_G2_M_CHECKPOINTS

PSMA4 PSMD7 CLSPN TP53BP1

9.22e-04143434MM15383
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

PTMS NEFM ARID4B UPF2 PPP1R12A SEC62 SYT1 TP53BP1 HDAC2

4.37e-1119160920195357
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RBM25 AKAP8 ARID4B UPF2 PRRC2C SF3A1 PSMA4 CAST PSMD7 ZC3H18 RBM28 CLSPN HDAC1 HDAC2 IWS1

7.23e-11971601533306668
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

DHX16 RBM25 AKAP8 CALR SF3A1 SEC62 DHX38 PSMD7 RBM28 EIF3J LETM1 HDAC1 IWS1

7.37e-11653601333742100
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

NEFM RBM25 UBXN4 CALD1 UPF2 PRRC2C SF3A1 PSMA4 PRPF38B PSMD7 HSP90AB2P RBM28 HDAC1 HDAC2

1.43e-10847601435235311
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

DHX16 AKAP8 SF3A1 DHX38 EIF3J HDAC1 HDAC2 IWS1

4.07e-1016360822113938
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DHX16 RBM25 WAPL AKAP8 ARID4B C9orf78 SF3A1 CAST PHF14 PRPF38B ZC3H18 TP53BP1 IWS1

5.87e-10774601315302935
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DHX16 NEDD8 RBM25 WAPL PSMA4 DHX38 PHF14 PRPF38B ZC3H18 MED13L EIF3J HDAC1 HDAC2 IWS1

1.46e-091014601432416067
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NEDD8 PTMS CALD1 CALR C9orf78 SF3A1 PPP1R12A PSMA4 DHX38 CAST PSMD7 HSP90AB2P HERC1 EIF3J HDAC1 IWS1

2.13e-091455601622863883
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NEFM RBM25 WAPL CALD1 PRRC2C PPP1R12A CAST PEAK1 TP53BP1 HDAC1 HDAC2

2.34e-09549601138280479
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RBM25 AKAP8 PRRC2C SF3A1 DHX38 PHF14 ZC3H18 RBM28 HDAC1 HDAC2 IWS1

6.39e-09605601128977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

DHX16 HMGN5 WAPL ARID4B CALR C9orf78 PHF14 ZC3H18 HDAC1 HDAC2 IWS1

6.72e-09608601136089195
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RBM25 WAPL ARID4B CALD1 PRRC2C SF3A1 CAST SYT1 PHF14 ZC3H18 RBM28 TP53BP1 HDAC2

7.20e-09954601336373674
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DHX16 PTMS WAPL AKAP8 CALD1 CALR C9orf78 SF3A1 PPP1R12A DHX38 EIF3J TP53BP1 HDAC2 NAA16

7.65e-091155601420360068
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

AKAP8 PRRC2C SF3A1 PPP1R12A TP53BP1 HDAC1 HDAC2

8.82e-0915360726365490
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX16 NEFM RBM25 CALR PRRC2C SF3A1 DHX38 ZC3H18 RBM28 TP53BP1 HDAC2

1.40e-08653601122586326
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NEDD8 NEFM UBXN4 CALD1 ARMC3 PRRC2C PPP1R12A SEC62 SANBR PHF14 PSMD7 TNNT1 LETM1 HDAC1 HDAC2

1.57e-081442601535575683
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DHX16 HMGN5 RBM25 WAPL UPF2 CALR SF3A1 PSMA4 DHX38 PRPF38B PSMD7 RBM28 HDAC1 HDAC2

3.99e-081318601430463901
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

NEFM AKAP8 CALD1 CALR PRRC2C SF3A1 PPP1R12A PSMA4 CAST PSMD7 EIF3J HDAC1 HDAC2

6.38e-081149601335446349
Pubmed

Human transcription factor protein interaction networks.

PTMS ZNF771 RBM25 AKAP8 ARID4B PRRC2C PSMA4 PSMD7 ZC3H18 PAX7 RBM28 HERC1 TP53BP1 HDAC2

1.08e-071429601435140242
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

WAPL UPF2 SF3A1 DHX38 ZC3H18 RBM28 TP53BP1 HDAC2

1.29e-0734160832971831
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

DHX16 NEFM ZCWPW1 WAPL AKAP8 ARID4B PRRC2C SF3A1 PPP1R12A TP53BP1 HDAC2

2.18e-07857601125609649
Pubmed

Identification and characterization of three new components of the mSin3A corepressor complex.

ARID4B HDAC1 HDAC2

2.72e-07860312724404
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

NEDD8 UBXN4 WAPL C9orf78 PPP1R12A SEC62 LETM1 HDAC1 HDAC2

4.86e-0756060935241646
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

WAPL CALD1 PRRC2C SF3A1 PPP1R12A PSMA4 DHX38 CAST PRPF38B PSMD7 TP53BP1

5.09e-07934601133916271
Pubmed

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.

ARID4B HDAC1 HDAC2

5.81e-071060321490601
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

PRRC2C C9orf78 SF3A1 PSMA4 DHX38 CAST ZC3H18 HSP90AB2P EIF3J LETM1 HDAC2 SPINK5 IWS1

6.88e-071415601328515276
Pubmed

CRL4B interacts with and coordinates the SIN3A-HDAC complex to repress CDKN1A and drive cell cycle progression.

ARID4B HDAC1 HDAC2

7.97e-071160325189618
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RBM25 WAPL AKAP8 SF3A1 DHX38 PHF14 HSP90AB2P RBM28 CLSPN TP53BP1 HDAC2

8.92e-07989601136424410
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

DHX16 HMGN5 RBM25 AKAP8 PRRC2C SF3A1 DHX38 ZC3H18 RBM28 HDAC2

1.13e-06807601022681889
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RBM25 WAPL AKAP8 SF3A1 PPP1R12A PSMA4 DHX38 ZC3H18 RBM28 HDAC1

1.75e-06847601035850772
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

HMGN5 RBM25 AKAP8 ARID4B SF3A1 DHX38 PHF14 ZC3H18 RBM28 HDAC1 HDAC2 IWS1

1.79e-061294601230804502
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ZCWPW1 ARID4B UPF2 SF3A1 DHX38 PHF14 PRPF38B ZC3H18 MED13L EIF3J CLSPN IWS1

2.33e-061327601232694731
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

DHX16 PTMS RBM25 CALD1 CALR SF3A1 PSMD7 TP53BP1

2.50e-0650660830890647
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PRRC2C C9orf78 SF3A1 PSMA4 PRPF38B PSMD7 RBM28 MED13L TP53BP1 HDAC1 HDAC2

2.56e-061103601134189442
Pubmed

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.

SF3A1 HDAC1 HDAC2

2.69e-061660311013263
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NEDD8 ZNF771 RBM25 WAPL AKAP8 ARID4B PPP1R12A ZC3H18 CLSPN HDAC1 HDAC2

2.87e-061116601131753913
Pubmed

The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle.

HDAC1 HDAC2

2.93e-06260235575026
Pubmed

Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis.

HDAC1 HDAC2

2.93e-06260223792463
Pubmed

Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.

HDAC1 HDAC2

2.93e-06260219531758
Pubmed

Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro.

HDAC1 HDAC2

2.93e-06260231222845
Pubmed

The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.

HDAC1 HDAC2

2.93e-06260224525021
Pubmed

12q21 deletion syndrome: Narrowing the critical region down to 1.6 Mb including SYT1 and PPP1R12A.

PPP1R12A SYT1

2.93e-06260232633079
Pubmed

HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.

HDAC1 HDAC2

2.93e-06260211287668
Pubmed

Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development.

HDAC1 HDAC2

2.93e-06260231533525
Pubmed

Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown.

HDAC1 HDAC2

2.93e-06260234890513
Pubmed

Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts.

HDAC1 HDAC2

2.93e-06260232366868
Pubmed

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

HDAC1 HDAC2

2.93e-06260221423190
Pubmed

Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.

HDAC1 HDAC2

2.93e-06260224335310
Pubmed

Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway.

HDAC1 HDAC2

2.93e-06260238523117
Pubmed

Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC.

HDAC1 HDAC2

2.93e-06260218408217
Pubmed

HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.

HDAC1 HDAC2

2.93e-06260228579617
Pubmed

HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition.

HDAC1 HDAC2

2.93e-06260229641990
Pubmed

HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.

HDAC1 HDAC2

2.93e-06260224040068
Pubmed

Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.

HDAC1 HDAC2

2.93e-06260226174178
Pubmed

[Regulatory effect of ginsenoside Rh2 on HDAC1/2 activity and cyclin in human erythroleukemia K562 cells].

HDAC1 HDAC2

2.93e-06260225270209
Pubmed

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

HDAC1 HDAC2

2.93e-06260222156779
Pubmed

Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer.

HDAC1 HDAC2

2.93e-06260223251689
Pubmed

Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity.

HDAC1 HDAC2

2.93e-06260232934238
Pubmed

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.

HDAC1 HDAC2

2.93e-06260220802485
Pubmed

Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.

HDAC1 HDAC2

2.93e-06260231799598
Pubmed

The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31.

HDAC1 HDAC2

2.93e-06260215016876
Pubmed

Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions.

HDAC1 HDAC2

2.93e-06260211919195
Pubmed

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia.

HDAC1 HDAC2

2.93e-06260221292776
Pubmed

Genetic dissection of histone deacetylase requirement in tumor cells.

HDAC1 HDAC2

2.93e-06260219416910
Pubmed

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

HDAC1 HDAC2

2.93e-06260223287868
Pubmed

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells.

HDAC1 HDAC2

2.93e-06260231071955
Pubmed

Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers.

HDAC1 HDAC2

2.93e-06260225942572
Pubmed

Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function.

HDAC1 HDAC2

2.93e-06260219553468
Pubmed

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

HDAC1 HDAC2

2.93e-06260224449838
Pubmed

HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.

HDAC1 HDAC2

2.93e-06260220398369
Pubmed

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice.

HDAC1 HDAC2

2.93e-06260222307625
Pubmed

Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease.

HDAC1 HDAC2

2.93e-06260226116233
Pubmed

Dynamic distribution of HDAC1 and HDAC2 during mitosis: association with F-actin.

HDAC1 HDAC2

2.93e-06260223280436
Pubmed

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.

HDAC1 HDAC2

2.93e-06260225688158
Pubmed

Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse.

HDAC1 HDAC2

2.93e-06260223516383
Pubmed

Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection.

HDAC1 HDAC2

2.93e-06260219740981
Pubmed

NuRD and SIN3 histone deacetylase complexes in development.

HDAC1 HDAC2

2.93e-06260210904264
Pubmed

HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.

HDAC1 HDAC2

2.93e-06260225648995
Pubmed

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.

HDAC1 HDAC2

2.93e-06260217639084
Pubmed

Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly.

HDAC1 HDAC2

2.93e-06260230209338
Pubmed

HDAC1 and HDAC2 are differentially expressed in endometriosis.

HDAC1 HDAC2

2.93e-06260222344732
Pubmed

HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.

HDAC1 HDAC2

2.93e-06260230926862
Pubmed

Trans-regulation of histone deacetylase activities through acetylation.

HDAC1 HDAC2

2.93e-06260219822520
Pubmed

Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer.

HDAC1 HDAC2

2.93e-06260231692265
Pubmed

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.

HDAC1 HDAC2

2.93e-06260215297431
Pubmed

Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.

HDAC1 HDAC2

2.93e-06260224958871
Pubmed

Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.

HDAC1 HDAC2

2.93e-06260220585871
Pubmed

Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.

HDAC1 HDAC2

2.93e-06260226129908
Pubmed

Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation.

HDAC1 HDAC2

2.93e-06260219412887
Pubmed

A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes.

HDAC1 HDAC2

2.93e-06260219561124
Pubmed

HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population.

HDAC1 HDAC2

2.93e-06260226352599
Pubmed

Leucine zipper domain is required for Kaposi sarcoma-associated herpesvirus (KSHV) K-bZIP protein to interact with histone deacetylase and is important for KSHV replication.

HDAC1 HDAC2

2.93e-06260222416134
Pubmed

Histone deacetylase 1 and 2 in mesenchymal tumors.

HDAC1 HDAC2

2.93e-06260222037263
Pubmed

Loss of histone deacetylase 2 improves working memory and accelerates extinction learning.

HDAC1 HDAC2

2.93e-06260223575838
Pubmed

Podocyte histone deacetylase activity regulates murine and human glomerular diseases.

HDAC1 HDAC2

2.93e-06260230776024
Pubmed

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

HDAC1 HDAC2

2.93e-06260221270520
Pubmed

Direct interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha1A subunit of the P/Q-type calcium channel.

CACNA1A SYT1

2.93e-0626029303303
Pubmed

HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer.

HDAC1 HDAC2

2.93e-06260230669676
Pubmed

JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice.

HDAC1 HDAC2

2.93e-06260233498747
Pubmed

Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy.

HDAC1 HDAC2

2.93e-06260221725353
InteractionFLII interactions

RBM25 WAPL AKAP8 CALD1 CALR C9orf78 PPP1R12A HERC1 HDAC1 HDAC2

1.42e-082985910int:FLII
InteractionEP300 interactions

DHX16 PTMS RBM25 AKAP8 CALR SF3A1 SEC62 DHX38 PSMD7 PAX7 RBM28 HERC1 EIF3J LETM1 TP53BP1 HDAC1 HDAC2 IWS1

5.38e-0814015918int:EP300
InteractionCSNK2A1 interactions

DHX16 AKAP8 ARID4B CALD1 PRRC2C SF3A1 PSMA4 DHX38 ZC3H18 HSP90AB2P PAX7 EIF3J HDAC1 HDAC2 IWS1

6.98e-089565915int:CSNK2A1
InteractionPOLR1G interactions

DHX16 ARID4B C9orf78 DHX38 PHF14 PSMD7 ZC3H18 RBM28 CLSPN HDAC1 IWS1

1.50e-074895911int:POLR1G
InteractionSERF2 interactions

DHX16 UPF2 C9orf78 DHX38 PRPF38B IWS1

2.04e-0787596int:SERF2
InteractionSAP18 interactions

RBM25 ARID4B CALD1 UPF2 SF3A1 PRPF38B ZC3H18 HDAC1 HDAC2

2.40e-07305599int:SAP18
InteractionPARP1 interactions

DHX16 NEDD8 HMGN5 RBM25 ARID4B CALD1 CALR C9orf78 SF3A1 PHF14 ZC3H18 RBM28 CLSPN TP53BP1 HDAC1 HDAC2

7.52e-0713165916int:PARP1
InteractionFZR1 interactions

RBM25 AKAP8 ARID4B UPF2 PRRC2C SF3A1 PSMA4 CAST PSMD7 ZC3H18 RBM28 CLSPN HDAC1 HDAC2 IWS1

9.54e-0711725915int:FZR1
InteractionCHD3 interactions

RBM25 AKAP8 ARID4B PRRC2C SF3A1 DHX38 PHF14 ZC3H18 RBM28 TNNT1 HDAC1 HDAC2

1.60e-067575912int:CHD3
InteractionNR2C2 interactions

DHX16 HMGN5 RBM25 WAPL UPF2 CALR SF3A1 PSMA4 DHX38 PRPF38B PSMD7 PAX7 RBM28 TP53BP1 HDAC1 HDAC2

1.75e-0614035916int:NR2C2
InteractionCBX3 interactions

DHX16 PTMS HMGN5 WAPL CALR C9orf78 PPP1R12A DHX38 CLSPN TP53BP1 HDAC2

2.33e-066465911int:CBX3
InteractionDEK interactions

DHX16 RBM25 PPP1R12A PHF14 ZC3H18 TP53BP1 HDAC2

2.52e-06209597int:DEK
InteractionCEBPB interactions

NEDD8 RBM25 AKAP8 CALR PRRC2C SF3A1 CAST PHF14 HSP90AB2P EIF3J TEF LETM1 TP53BP1 HDAC1 HDAC2 IWS1

2.53e-0614435916int:CEBPB
InteractionTAF15 interactions

NEDD8 CACNA1A RBM25 CALD1 SF3A1 PPP1R12A ZC3H18 TP53BP1 HDAC2

2.69e-06408599int:TAF15
InteractionCIT interactions

DHX16 NEFM RBM25 CALR PRRC2C SF3A1 PPP1R12A DHX38 PRPF38B PNPLA8 HSP90AB2P RBM28 HERC1 HDAC1 HDAC2 IWS1

2.69e-0614505916int:CIT
InteractionNAA40 interactions

DHX16 HMGN5 WAPL CALD1 PRRC2C SF3A1 PPP1R12A PSMA4 DHX38 CAST PRPF38B PSMD7 TP53BP1

3.87e-069785913int:NAA40
InteractionCHAF1A interactions

AKAP8 ARID4B PRRC2C SF3A1 PPP1R12A TP53BP1 HDAC1 HDAC2

4.25e-06322598int:CHAF1A
InteractionSMC5 interactions

RBM25 WAPL ARID4B CALD1 PRRC2C SF3A1 CAST SYT1 PHF14 ZC3H18 RBM28 TP53BP1 HDAC2

4.93e-0610005913int:SMC5
InteractionKLF8 interactions

ZNF771 AKAP8 ARID4B PRRC2C PSMA4 PSMD7 RBM28 HDAC2

4.98e-06329598int:KLF8
InteractionENO1 interactions

RBM25 UPF2 CALR C9orf78 SF3A1 PPP1R12A ZC3H18 TP53BP1 HDAC1 HDAC2 IWS1

5.09e-067015911int:ENO1
InteractionZBTB2 interactions

SF3A1 PPP1R12A PHF14 ZC3H18 RBM28 EIF3J TP53BP1 HDAC1 HDAC2

5.95e-06450599int:ZBTB2
InteractionCSNK2A2 interactions

ARID4B PRRC2C SF3A1 PHF14 PSMD7 ZC3H18 HSP90AB2P EIF3J TP53BP1 HDAC1 HDAC2

6.40e-067185911int:CSNK2A2
InteractionSYNCRIP interactions

NEDD8 PRRC2C SF3A1 SYT1 PNPLA8 PSMD7 ZC3H18 RBM28 MED13L LETM1 HDAC2

6.65e-067215911int:SYNCRIP
InteractionHNRNPU interactions

NEDD8 CALR SF3A1 PPP1R12A SEC62 PHF14 PSMD7 ZC3H18 RBM28 EIF3J HDAC1 HDAC2 NAA16

7.16e-0610355913int:HNRNPU
InteractionDHX40 interactions

DHX16 AKAP8 DHX38 ZC3H18 RBM28 HERC1 CLSPN

7.97e-06249597int:DHX40
InteractionSMARCC2 interactions

RBM25 ARID4B UPF2 SF3A1 PPP1R12A TP53BP1 HDAC1 HDAC2

8.33e-06353598int:SMARCC2
InteractionSIRT7 interactions

DHX16 NEFM RBM25 CALR PRRC2C SF3A1 DHX38 ZC3H18 RBM28 TP53BP1 HDAC2

8.95e-067445911int:SIRT7
InteractionH3C1 interactions

NEDD8 HMGN5 WAPL ARID4B PRRC2C C9orf78 DHX38 CAST RBM28 TP53BP1 HDAC1 HDAC2

9.52e-069015912int:H3C1
InteractionDDX23 interactions

DHX16 NEFM RBM25 C9orf78 SF3A1 DHX38 ZC3H18 RBM28 IWS1

9.99e-06480599int:DDX23
InteractionSMARCB1 interactions

RBM25 ARID4B CALR SF3A1 PPP1R12A TP53BP1 HDAC1 HDAC2

1.04e-05364598int:SMARCB1
InteractionCALD1 interactions

NEFM ARID4B CALD1 PRRC2C PPP1R12A SEC62 PEAK1

1.20e-05265597int:CALD1
InteractionPPP4R3A interactions

RBM25 C9orf78 SF3A1 DHX38 CAST HDAC1

1.38e-05179596int:PPP4R3A
InteractionSAP130 interactions

ARID4B C9orf78 PAX7 TP53BP1 HDAC1 HDAC2

1.47e-05181596int:SAP130
InteractionSMARCC1 interactions

RBM25 ARID4B C9orf78 SF3A1 PPP1R12A TP53BP1 HDAC1 HDAC2

1.53e-05384598int:SMARCC1
InteractionMECP2 interactions

DHX16 NEFM RBM25 AKAP8 UPF2 SF3A1 PHF14 PRPF38B ZC3H18 RBM28 TP53BP1 HDAC1 HDAC2 IWS1

1.54e-0512875914int:MECP2
InteractionPLK1 interactions

NEFM RBM25 WAPL C9orf78 PPP1R12A PSMA4 CLSPN TP53BP1 HDAC2

1.62e-05510599int:PLK1
InteractionPRC1 interactions

RBM25 AKAP8 SF3A1 PPP1R12A PHF14 PRPF38B PNPLA8 PSMD7 ZC3H18 RBM28 HERC1 HDAC2

2.05e-059735912int:PRC1
InteractionEPB41L2 interactions

RBM25 CALD1 UPF2 C9orf78 PPP1R12A SEC62 ZC3H18

2.60e-05299597int:EPB41L2
InteractionPSMA6 interactions

NEDD8 UBXN4 CALR SF3A1 PSMA4 CAST PSMD7

2.95e-05305597int:PSMA6
InteractionWWTR1 interactions

NEFM RBM25 WAPL CALD1 PRRC2C PPP1R12A PEAK1 TP53BP1

3.01e-05422598int:WWTR1
InteractionTOP1 interactions

DHX16 RBM25 AKAP8 ARID4B PHF14 ZC3H18 RBM28 EIF3J TNNT1 IWS1

3.08e-056965910int:TOP1
InteractionHSPB1 interactions

HMGN5 CFAP251 RBM25 AKAP8 CALR PRRC2C CAST ZC3H18 LETM1 HDAC1

3.56e-057085910int:HSPB1
InteractionMEN1 interactions

RBM25 WAPL AKAP8 UPF2 SF3A1 PSMA4 DHX38 ZC3H18 RBM28 TP53BP1 HDAC1 HDAC2

3.56e-0510295912int:MEN1
InteractionIFI27L1 interactions

DHX16 RBM25 C9orf78 PRPF38B

3.93e-0565594int:IFI27L1
InteractionPPP1R12A interactions

NEFM RBM25 CALD1 C9orf78 PPP1R12A PSMA4 HDAC2

4.17e-05322597int:PPP1R12A
InteractionRBM25 interactions

RBM25 UPF2 SF3A1 PPP1R12A ZC3H18 RBM28 HDAC1

4.25e-05323597int:RBM25
InteractionNSUN2 interactions

CALD1 CALR PPP1R12A PSMA4 RBM28 TP53BP1 HDAC2

4.25e-05323597int:NSUN2
InteractionACTR2 interactions

CALD1 UPF2 CALR PPP1R12A PSMA4 PSMD7 HSP90AB2P

4.25e-05323597int:ACTR2
InteractionMAU2 interactions

WAPL AKAP8 MED13L TP53BP1 HDAC2

4.86e-05136595int:MAU2
InteractionFOXK2 interactions

ARID4B PRRC2C SEC62 TP53BP1 HDAC1 HDAC2

4.98e-05225596int:FOXK2
InteractionBRCA1 interactions

HMGN5 WAPL AKAP8 SF3A1 DHX38 PSMD7 HSP90AB2P RBM28 HERC1 CLSPN TP53BP1 HDAC1 HDAC2

5.21e-0512495913int:BRCA1
InteractionH3-3A interactions

DHX16 NEDD8 HMGN5 WAPL ARID4B C9orf78 PHF14 HDAC1 HDAC2 IWS1

5.72e-057495910int:H3-3A
InteractionCWC22 interactions

RBM25 C9orf78 SEC62 SYT1 ZC3H18

5.77e-05141595int:CWC22
InteractionCD2BP2 interactions

C9orf78 SF3A1 DHX38 PRPF38B ZC3H18 TP53BP1

5.91e-05232596int:CD2BP2
InteractionNCAPD2 interactions

CALR C9orf78 PSMD7 EDN3 HDAC1 HDAC2

6.19e-05234596int:NCAPD2
InteractionYAP1 interactions

NEDD8 NEFM RBM25 WAPL CALD1 PRRC2C SF3A1 PPP1R12A PSMA4 CAST HDAC1 HDAC2

6.50e-0510955912int:YAP1
InteractionRBM8A interactions

PTMS UPF2 PRRC2C SF3A1 DHX38 ZC3H18 RBM28 EIF3J

6.73e-05473598int:RBM8A
InteractionSRRM1 interactions

DHX16 RBM25 WAPL CALD1 UPF2 SF3A1 ZC3H18

6.80e-05348597int:SRRM1
InteractionPWWP2A interactions

HMGN5 ARID4B HDAC1 HDAC2

7.26e-0576594int:PWWP2A
InteractionC9orf78 interactions

NEDD8 UBXN4 WAPL C9orf78 PPP1R12A SEC62 LETM1 HDAC1 HDAC2

7.41e-05620599int:C9orf78
InteractionCHD4 interactions

RBM25 AKAP8 PRRC2C SF3A1 PPP1R12A PHF14 ZC3H18 RBM28 HDAC1 HDAC2 IWS1

7.53e-059385911int:CHD4
InteractionCYP1A1 interactions

HMGN5 SF3A1 EIF3J LETM1

7.64e-0577594int:CYP1A1
InteractionEIF3A interactions

CACNA1A CALD1 PRRC2C PHF14 PRPF38B ZC3H18 EIF3J

7.70e-05355597int:EIF3A
InteractionCOPS3 interactions

NEDD8 RBM25 ARID4B PPP1R12A PSMD7 HDAC1

7.98e-05245596int:COPS3
InteractionRAB3GAP2 interactions

RBM25 UPF2 C9orf78 SEC62 HDAC1

8.24e-05152595int:RAB3GAP2
InteractionZNF827 interactions

TP53BP1 HDAC1 HDAC2

8.25e-0529593int:ZNF827
InteractionC22orf31 interactions

HDAC1 HDAC2

8.38e-055592int:C22orf31
InteractionADARB1 interactions

ZNF771 RBM25 WAPL SF3A1 PHF14 RBM28 TP53BP1 HDAC2

8.49e-05489598int:ADARB1
InteractionBAP1 interactions

NEFM AKAP8 CALD1 CALR PRRC2C SF3A1 PPP1R12A PSMA4 CAST PSMD7 EIF3J HDAC1 HDAC2

8.75e-0513145913int:BAP1
InteractionSNRNP40 interactions

DHX16 RBM25 AKAP8 C9orf78 SF3A1 DHX38 ZC3H18 RBM28 HDAC2

9.11e-05637599int:SNRNP40
InteractionRCOR1 interactions

NEFM HMGN5 C9orf78 PPP1R12A PAX7 TP53BP1 HDAC1 HDAC2

9.11e-05494598int:RCOR1
InteractionH3C3 interactions

WAPL CALR C9orf78 PHF14 ZC3H18 HDAC1 HDAC2 IWS1

9.24e-05495598int:H3C3
InteractionHSP90AB1 interactions

CALR PRRC2C C9orf78 PPP1R12A CAST ZC3H18 HSP90AB2P PEAK1 TNNT1 HDAC1 HDAC2

9.26e-059605911int:HSP90AB1
InteractionMED18 interactions

MED13L TP53BP1 HDAC1 HDAC2

9.32e-0581594int:MED18
InteractionPSMC1 interactions

C9orf78 SF3A1 PSMA4 PSMD7 TP53BP1 HDAC1 HDAC2

9.64e-05368597int:PSMC1
InteractionSUZ12 interactions

HMGN5 CALR C9orf78 SF3A1 PHF14 ZC3H18 EIF3J HDAC1 HDAC2

9.90e-05644599int:SUZ12
InteractionNFE2L2 interactions

EIF3J TEF TNNT1 HDAC1 HDAC2

1.02e-04159595int:NFE2L2
InteractionCABIN1 interactions

CALD1 TP53BP1 HDAC1 HDAC2

1.02e-0483594int:CABIN1
InteractionGTF2I interactions

RBM25 WAPL C9orf78 PSMA4 ZC3H18 HDAC1 HDAC2

1.05e-04373597int:GTF2I
InteractionNR2C1 interactions

PAX7 TP53BP1 HDAC1 HDAC2

1.07e-0484594int:NR2C1
InteractionMBD2 interactions

ARID4B C9orf78 PSMD7 HDAC1 HDAC2

1.08e-04161595int:MBD2
InteractionNXF1 interactions

RBM25 AKAP8 UPF2 SF3A1 DHX38 ZC3H18 HSP90AB2P CLSPN ANKRD33B TP53BP1 HDAC1 HDAC2 IWS1

1.11e-0413455913int:NXF1
InteractionAKT3 interactions

PTMS CALD1 HERC1 IWS1

1.12e-0485594int:AKT3
InteractionSNRNP70 interactions

RBM25 AKAP8 UPF2 PRRC2C SF3A1 PPP1R12A PRPF38B ZC3H18 RBM28 HDAC1 HDAC2

1.15e-049845911int:SNRNP70
InteractionMIF interactions

PTMS UPF2 CALR PHF14 ZC3H18 CLSPN

1.20e-04264596int:MIF
InteractionBRCA2 interactions

UBXN4 PHF14 HERC1 CLSPN TP53BP1 HDAC1 HDAC2

1.26e-04384597int:BRCA2
InteractionSS18 interactions

NEFM PAX7 HDAC1 HDAC2

1.29e-0488594int:SS18
InteractionTOP2A interactions

DHX16 HMGN5 PRRC2C C9orf78 ZC3H18 HDAC1 HDAC2 IWS1

1.30e-04520598int:TOP2A
InteractionMYCN interactions

ZNF771 NEFM AKAP8 UPF2 PRRC2C C9orf78 SF3A1 PRPF38B PSMD7 ZC3H18 RBM28 HDAC1 HDAC2

1.36e-0413735913int:MYCN
InteractionTGIF2LX interactions

ARID4B HDAC1 HDAC2

1.59e-0436593int:TGIF2LX
InteractionTAL1 interactions

PTMS RBM25 HDAC1 HDAC2

1.59e-0493594int:TAL1
InteractionHSPD1 interactions

NEDD8 PTMS NEFM PRRC2C C9orf78 SF3A1 ZC3H18 MED13L LETM1 HDAC1 HDAC2

1.61e-0410225911int:HSPD1
InteractionATF3 interactions

CALD1 TP53BP1 HDAC1 HDAC2

1.66e-0494594int:ATF3
InteractionTPR interactions

CALD1 PRRC2C PPP1R12A SEC62 CAST HDAC1

1.69e-04281596int:TPR
InteractionRREB1 interactions

SF3A1 PAX7 HDAC1 HDAC2

1.73e-0495594int:RREB1
InteractionDNTTIP1 interactions

NEFM PAX7 HDAC1 HDAC2

1.73e-0495594int:DNTTIP1
InteractionSMURF1 interactions

NEDD8 NEFM AKAP8 C9orf78 SF3A1 PSMA4 TNNT1 NAA16

1.77e-04544598int:SMURF1
InteractionMAP1LC3B interactions

DHX16 RBM25 UPF2 PRRC2C SEC62 PRPF38B LETM1 HDAC1

1.93e-04551598int:MAP1LC3B
InteractionSMARCD2 interactions

UPF2 PAX7 TP53BP1 HDAC1 HDAC2

1.97e-04183595int:SMARCD2
InteractionKLF15 interactions

PTMS ZNF771 AKAP8 ARID4B PRRC2C PSMA4

2.00e-04290596int:KLF15
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

2.86e-054402989
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

1.70e-0494021306
GeneFamilyPHD finger proteins|NuRD complex

HDAC1 HDAC2

3.11e-04124021305
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

3.11e-04124021243
GeneFamilyDEAH-box helicases

DHX16 DHX38

5.62e-0416402500
GeneFamilyProteasome

PSMA4 PSMD7

4.07e-0343402690
CoexpressionMENON_FETAL_KIDNEY_4_PODOCYTES

PTMS CALD1 CALR PRRC2C SEC62 CAST

6.98e-06206596M39254
CoexpressionBUSSLINGER_GASTRIC_ISTHMUS_CELLS

RBM25 CALR PSMA4 CAST PRPF38B PSMD7 EIF3J SPINK5

8.31e-06458598M40010
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

ARID4B CALD1 PSMA4 SEC62 CAST PRPF38B EIF3J HDAC2 IWS1

1.50e-05656599M18979
CoexpressionQI_PBMC_ZOSTAVAX_AGE_50_75YO_CORRELATED_WITH_EXPANSION_OF_VZV_SPECIFIC_T_CELLS_TO_PEAK_AT_1DY_POSITIVE

UBXN4 UPF2 PRRC2C DHX38 CAST IWS1

2.00e-05248596M40874
CoexpressionTABULA_MURIS_SENIS_BRAIN_NON_MYELOID_OLIGODENDROCYTE_AGEING

NEDD8 PTMS ZNF771 RBM25 UBXN4 CALD1 CALR C9orf78 PSMA4 PRPF38B PSMD7

4.09e-0511395911MM3690
CoexpressionEIF4E_DN

ARID4B UPF2 PRRC2C TP53BP1

7.73e-05100594M2790
CoexpressionPUJANA_BREAST_CANCER_LIT_INT_NETWORK

CLSPN TP53BP1 HDAC1 HDAC2

8.03e-05101594M15356
CoexpressionGSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP

WAPL PRRC2C SEC62 CAST HERC1

8.41e-05198595M8036
CoexpressionHALLMARK_MYC_TARGETS_V1

SF3A1 PSMA4 PSMD7 EIF3J HDAC2

8.82e-05200595M5926
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

HMGN5 RBM25 WAPL ARID4B CALD1 PHF14 PRPF38B PEAK1 CLSPN EGFL6

8.73e-092985910Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000

CACNA1A HMGN5 RBM25 ZCWPW1 WAPL ARID4B CALD1 SANBR PHF14 PRPF38B PAX7 PEAK1 CLSPN EGFL6 IWS1

4.82e-089795915Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

HMGN5 RBM25 WAPL UPF2 PRRC2C DHX38 PRPF38B CLSPN NAA16 IWS1

5.99e-074695910Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

CACNA1A NEFM HMGN5 RBM25 AKAP8 SANBR PHF14 PRPF38B PEAK1 CLSPN TNNT1 EGFL6 IWS1

2.31e-069835913Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

HMGN5 RBM25 PHF14 PRPF38B PEAK1 CLSPN EGFL6

5.25e-06246597Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

HMGN5 ARID4B UPF2 PPP1R12A SANBR PRPF38B PNPLA8 CLSPN EGFL6 IWS1

8.22e-066295910Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

HMGN5 ARID4B PHF14 PRPF38B CLSPN LETM1 IWS1

2.40e-05311597Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

CACNA1A NEFM HMGN5 RBM25 WAPL ARID4B CALD1 SANBR PHF14 PRPF38B PNPLA8 CLSPN NAA16

3.11e-0512525913facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A NEFM RBM25 AKAP8 SANBR PHF14 PRPF38B CLSPN IWS1

7.49e-05654599Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

CACNA1A NEFM HMGN5 ARID4B SANBR PHF14 PRPF38B EIF3J CLSPN LETM1 IWS1

7.59e-059895911Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

PTMS ZNF771 CACNA1A NEFM HMGN5 RBM25 ARID4B SANBR PHF14 PRPF38B CLSPN TEF TP53BP1

7.87e-0513705913facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000

NEDD8 PTMS NEFM RBM25 ARID4B CALD1 DHX38 PSMD7 MED13L HDAC2

1.00e-048445910gudmap_developingGonad_e11.5_testes and mesonephros_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

HMGN5 RBM25 ARID4B CALD1 PSMA4 PHF14 PRPF38B PNPLA8 CLSPN EDN3 HDAC2 NAA16

1.30e-0412415912facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

CACNA1A HMGN5 RBM25 WAPL ARID4B SANBR PHF14 PRPF38B HERC1 CLSPN TP53BP1

1.40e-0410605911facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

HMGN5 RBM25 WAPL ARID4B UPF2 SANBR PHF14 PRPF38B CLSPN TP53BP1 NAA16 IWS1

1.47e-0412575912facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

NEFM HMGN5 RBM25 WAPL ARID4B UPF2 SANBR PHF14 PRPF38B CLSPN TP53BP1 NAA16 IWS1

1.48e-0414595913facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

CACNA1A NEFM AKAP8 SANBR CLSPN IWS1

1.75e-04298596Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

NEFM SANBR PRPF38B CLSPN IWS1

1.93e-04192595Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

RBM25 WAPL ARID4B CALD1 PHF14 PRPF38B PAX7 PEAK1 EGFL6

1.98e-04744599Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

RBM25 CALD1 PRRC2C PRPF38B HERC1 TEF TNNT1 EDN3 EGFL6

3.30e-04797599gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

NEFM HMGN5 RBM25 CALD1 PRRC2C PRPF38B PSMD7 HERC1 HDAC2

3.58e-04806599gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

CACNA1A NEFM HMGN5 RBM25 WAPL ARID4B SANBR PHF14 PRPF38B HERC1 CLSPN TP53BP1

4.35e-0414145912facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

HMGN5 RBM25 ARID4B CALD1 PSMA4 PHF14 PRPF38B PNPLA8 CLSPN EDN3 HDAC2 NAA16

6.09e-0414685912facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

RBM25 WAPL PRRC2C DHX38 SANBR CLSPN IWS1

6.58e-04532597Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

HMGN5 RBM25 UPF2 PRRC2C PHF14 PRPF38B RBM28 EIF3J CLSPN

6.00e-121976090fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM25 UBXN4 WAPL ARID4B UPF2 PRRC2C

1.98e-07187606663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM25 UBXN4 ARID4B PRRC2C SEC62 PRPF38B

2.04e-07188606d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellCOVID-19_Severe-PLT_4|World / Disease Group and Platelet Clusters

UBXN4 ARID4B UPF2 PPP1R12A SEC62 EIF3J

2.61e-07196606ad43efdd4d73b6615f65f06a315b33576e317473
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGB ARMC3 SMIM31 SPINK5 CFAP65

2.81e-06164605e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

RBM25 WAPL ARID4B PRRC2C PHF14

5.06e-06185605857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

WAPL ARID4B UPF2 PPP1R12A IWS1

5.20e-0618660503db813598b67b1e08f759758a1c2023396921fa
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RBM25 ARID4B HERC1 MED13L TP53BP1

5.47e-06188605ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP251 ARMC3 PAX7 CFAP65

6.22e-06193605ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL ARID4B PRRC2C PPP1R12A TEF

6.38e-06194605e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CALD1 ARMC3 SEC62 RBM28 EIF3J

6.54e-0619560532ec72103faccc9e37c0ecedff1998e7df6a19f6
ToppCell15-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

PTMS SYT1 PAX7 TNNT1 EDN3

6.54e-061956059e9283a397f56732a0a5f2e2527f154d4c2dd56a
ToppCell3'|World / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEDD8 PSMA4 SEC62 PRPF38B EIF3J

6.70e-0619660544007f0c14e0f0703f7ee715b8eababb4d80a8b5
ToppCell3'-Adult-Distal_Rectal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTMS CALR PRRC2C SMIM31 SPINK5

7.04e-061986057ad7726fc405806b1d7824f58548073ea5e0c70b
ToppCell3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTMS CALR PRRC2C SMIM31 SPINK5

7.04e-061986051fbec311f2c987ca90a023a5989128c05aa12d5c
ToppCellCOVID-19_Severe-PLT_4|COVID-19_Severe / Disease Group and Platelet Clusters

UBXN4 ARID4B UPF2 PPP1R12A EIF3J

7.04e-06198605abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCell3'-Adult-Distal_Rectal-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTMS CALR PRRC2C SMIM31 SPINK5

7.04e-06198605ceede961ad9af6a3159db7efaa5087bf38aafc2d
ToppCell3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTMS CALR PRRC2C SMIM31 SPINK5

7.04e-061986054f26a60e99f42343e5af7221723e108a1a1b7827
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

ARID4B PRRC2C SYT1 PHF14 HDAC2

7.04e-06198605de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CALD1 PPP1R12A CAST MCTP2 EGFL6

7.04e-0619860572aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

RBM25 UBXN4 ARID4B PRRC2C IWS1

7.22e-0619960553ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

RBM25 PRRC2C PAX7 TNNT1 EDN3

7.39e-062006057c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CALD1 PPP1R12A SYT1 MCTP2 EGFL6

7.39e-06200605f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RBM25 ARID4B PRRC2C CAST MED13L

7.39e-0620060512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellControl-Epithelial_airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARMC3 SMIM31 SPINK5 CFAP65

6.13e-0515860435aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP251 ARMC3 CFAP65

7.95e-0516960414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

CALD1 ARMC3 MCTP2 EGFL6

8.13e-05170604d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ARID4B PRRC2C C9orf78 EGFL6

8.32e-0517160461318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PNPLA8 PAX7 SMIM31 SPINK5

8.32e-051716040597339618fb4d416d55c538eceb353218a55002
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PNPLA8 PAX7 SMIM31 SPINK5

8.32e-051716040de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 PPP1R12A MCTP2 EGFL6

8.51e-05172604107417cfab7775bc1f80807115047abfb50b7a7e
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ADGB CFAP251 ARMC3 CFAP65

8.51e-05172604187ae91148d293537afc77e10da2b64302322224
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP251 ARMC3 CFAP65

9.30e-05176604dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

HMGN5 UPF2 HERC1 TEF

9.51e-05177604e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

9.72e-05178604de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB CFAP251 ARMC3 SMIM31

9.93e-051796040e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Ciliated|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADGB CFAP251 ARMC3 CFAP65

1.04e-041816048eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4|TCGA-Endometrium / Sample_Type by Project: Shred V9

ADGB CFAP251 ARMC3 CFAP65

1.04e-0418160451d91b923920463245e95d65c6a5197e21d34d73
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.04e-04181604dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.06e-041826047ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ADGB CFAP251 ARMC3 CFAP65

1.06e-04182604fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

ADGB CFAP251 ARMC3 CFAP65

1.06e-04182604e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CALD1 MCTP2 EDN3 EGFL6

1.08e-041836048a799807fbf24456a9811e0c64068187940a2f71
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ADGB CFAP251 ARMC3 CFAP65

1.08e-04183604b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

ADGB CFAP251 ARMC3 CFAP65

1.08e-04183604cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB CFAP251 ARMC3 CFAP65

1.10e-04184604797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.10e-041846045daff849625f2f41d56615569c0ed59cd733b34c
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB CFAP251 ARMC3 CFAP65

1.10e-0418460477d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.13e-0418560430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.13e-041856043e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ADGB CFAP251 ARMC3 CFAP65

1.13e-0418560418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP251 ARMC3 CFAP65

1.13e-041856045e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.13e-041856040998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTMS CALD1 SYT1 EGFL6

1.15e-041866049579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP251 ARMC3 CFAP65

1.15e-0418660476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP251 ARMC3 CFAP65

1.15e-0418660485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RBM25 UPF2 PRRC2C MED13L

1.15e-0418660423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.17e-041876049e10ed56090d82589bc457788282f664b70ace4b
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.17e-04187604f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.20e-0418860434b11f72ca73153d02edcd09b38983ad1a504659
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.20e-0418860461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.20e-041886042b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGB CFAP251 ARMC3 CFAP65

1.22e-04189604a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.22e-0418960468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.22e-04189604c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

ADGB CFAP251 ARMC3 CFAP65

1.22e-04189604b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

ADGB CFAP251 ARMC3 CFAP65

1.22e-0418960427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADGB CFAP251 ARMC3 CFAP65

1.27e-041916042a8e6d560907e71e9f6e190ca0667da804e25641
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL PRRC2C CAST HDAC1

1.27e-0419160460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADGB CFAP251 ARMC3 CFAP65

1.27e-041916042d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB CFAP251 ARMC3 CFAP65

1.27e-04191604acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP251 ARMC3 CFAP65

1.27e-04191604e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADGB CFAP251 ARMC3 CFAP65

1.27e-0419160446c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP251 ARMC3 CFAP65

1.27e-041916049d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL PRRC2C CAST HDAC1

1.27e-0419160409db184cb90fe282a14474d7217068c58092c6f8
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ADGB CFAP251 ARMC3 CFAP65

1.27e-04191604995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADGB CFAP251 ARMC3 CFAP65

1.27e-04191604a37f20172b85566b9039254a89680e37fd503fd5
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 PRRC2C PAX7 EDN3

1.27e-041916047d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL PRRC2C CAST HDAC1

1.27e-04191604973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP251 ARMC3 CFAP65

1.27e-041916041c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

ADGB CFAP251 ARMC3 CFAP65

1.30e-04192604097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.30e-04192604d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTMS CALD1 CALR PSMA4

1.30e-041926048171a60df481195c39a7f740effcae8e4deb6ca7
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.30e-04192604eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.30e-04192604354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP251 ARMC3 CFAP65

1.33e-04193604e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal_differentiating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF771 PRRC2C TEF SPINK5

1.33e-0419360449f4fbec91acda4727703e0e359ed780eefb8a22
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTMS PAX7 TNNT1 EDN3

1.33e-0419360402dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ADGB CFAP251 ARMC3 CFAP65

1.33e-04193604a0baa8be6f590b2031fede22be588715ae458e93
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRC2C PAX7 TNNT1 EDN3

1.33e-041936041aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADGB CFAP251 ARMC3 CFAP65

1.35e-04194604756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

ADGB CFAP251 ARMC3 CFAP65

1.35e-04194604c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADGB CFAP251 ARMC3 CFAP65

1.35e-04194604b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP251 ARMC3 SANBR

1.35e-041946044a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP251 ARMC3 CFAP65

1.35e-041946041ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ADGB CFAP251 ARMC3 CFAP65

1.35e-0419460443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP251 ARMC3 CFAP65

1.38e-04195604d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP251 ARMC3 CFAP65

1.38e-0419560479dc031258579ea328181dda33710dd897f1064a
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CALD1 PAX7 TNNT1 EDN3

1.38e-04195604ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB CFAP251 ARMC3 CFAP65

1.38e-041956043486eae5fdb062a75a907b896c9d7b396d2aa195
ComputationalNeighborhood of RBBP6

RBM25 UBXN4 WAPL HDAC1

1.14e-0470394GNF2_RBBP6
ComputationalNeighborhood of CSNK1A1

RBM25 ARID4B EIF3J

2.90e-0436393GCM_CSNK1A1
Diseaseacute lymphoblastic leukemia (is_marker_for)

CAST HDAC1 HDAC2

4.13e-0534583DOID:9952 (is_marker_for)
Diseasealopecia areata (is_marker_for)

HDAC1 HDAC2

1.69e-0410582DOID:986 (is_marker_for)
Diseasepulmonary hypertension (is_marker_for)

TP53BP1 HDAC1 HDAC2

2.76e-0464583DOID:6432 (is_marker_for)
Diseasecognitive decline measurement

UBXN4 ZCWPW1 PRRC2C MED13L PPM1N EDN3

3.80e-04486586EFO_0007710
DiseaseMuscle hypotonia

PAX7 LETM1

5.07e-0417582C0026827
DiseaseIntellectual Disability

PPP1R12A SYT1 RBM28 MED13L LETM1

1.85e-03447585C3714756

Protein segments in the cluster

PeptideGeneStartEntry
KKEEEKKEEEEDDRG

CACNA1A

1196

O00555
EEDEVTKKRKDVKKD

ARID4B

796

Q4LE39
EEKMKEGLEDEKREE

EGFL6

336

Q8IUX8
QRGEKEDEDEDVKKR

AKAP8

356

O43823
EGKEIKDGKEVKDVK

ADGB

326

Q8N7X0
GKKEEEKVKEEEEVM

ARMC3

686

Q5W041
KREEEEEEEASEKGK

DHX16

131

O60231
KEAKEEKRKAEEAEK

ANKRD33B

461

A6NCL7
GKEDKKIVMEETEEK

CFAP251

66

Q8TBY9
LEEEKGKKEKERQEI

RBM25

291

P49756
ESVKKKGREEEDMEE

RBM28

216

Q9NW13
EKEGEEEKVAKRKAA

IWS1

381

Q96ST2
RIKFGKKEEEDEADK

PAX7

161

P23759
DEDDKESEKKGLIER

MCTP2

746

Q6DN12
VLKKKEESKEEDELG

MED13L

246

Q71F56
DKVERIKERVEEKEG

NEDD8

21

Q15843
EEEKTKEEKPEAKGV

HDAC1

461

Q13547
DDEKKEEAEVKPEVK

EIF3J

56

O75822
EEKKNDKEEKGKVEA

SPINK5

541

Q9NQ38
DKEEKGKVEAEKVKR

SPINK5

546

Q9NQ38
KEREKEISDGKAEEE

HSP90AB2P

141

Q58FF8
GKEEIEEKEEERDEK

CFAP65

1791

Q6ZU64
EEKESKEEEKGKHTR

HERC1

2271

Q15751
EEKEKAKEKAEKEVA

LETM1

721

O95202
KTDEEDDKEKEREKG

PEAK1

936

Q9H792
KKRDEEEEEASGLKE

NAA16

626

Q6N069
CKKKEREKEGREEEE

PPM1N

16

Q8N819
KEGKDVKVKEDEKER

HMGN5

221

P82970
VKVKEDEKEREDGKE

HMGN5

226

P82970
EGKEEDEIKEDDGKK

HMGN5

261

P82970
EKEKEREKEKEKATV

PHF14

126

O94880
AEKTDKEEEGKVEVK

EDN3

186

P14138
RLKEEEEDKKRKEEE

CALR

366

P27797
DEAKAKEEKLEKCGE

CAST

316

P20810
KAKEEDREKLGEKEE

CAST

461

P20810
GAKKARIEEDKKETE

HDAC2

441

Q92769
EEEEAKAEREKKEKE

PSMA4

241

P25789
ERKKKDEEKVKAEEE

UPF2

71

Q9HAU5
RDKSELEDKKVEEGK

PNPLA8

231

Q9NP80
GEEKEEPKEEEKLGK

SYT1

131

P21579
EEEEAKKRAEDDAKK

TNNT1

136

P13805
GEEDQRRKEEGEEKK

NBPF11

836

Q86T75
EKKEGQEKEESKKDR

PSMD7

286

P51665
EEREQRKEKEGEKAE

PRRC2C

1026

Q9Y520
RKEKEGEKAEKVTEK

PRRC2C

1031

Q9Y520
NEEEEHEKKGREKKR

SMIM31

36

A0A1B0GVY4
RLDKEKGKEKLEEDE

TEF

51

Q10587
VGDEEEVSKKQRKKE

SANBR

571

Q6NSI8
ERKKEEEEKEKERVA

SF3A1

256

Q15459
EDKEKEEEEEEKPKR

CALD1

186

Q05682
GEEKVEKEEKEEELE

CLSPN

646

Q9HAW4
KEKEEELEKEEGEKT

ZCWPW1

456

Q9H0M4
EEDEGEEKYEVVKLK

ZNF771

26

Q7L3S4
EKSDSEKKEDEEGKV

SEC62

311

Q99442
KERKKEVVEEEENGA

PTMS

31

P20962
VEEDEKNEAKKKKGE

TMIE

141

Q8NEW7
GEVEEKKHKEDKDDR

PRPF38B

396

Q5VTL8
KTDGTEEKHKKEEED

WAPL

1086

Q7Z5K2
EREEKDDGEDKKKSK

DHX38

61

Q92620
VEEEKGEELEQKEKE

TP53BP1

131

Q12888
KLKERGKDKISEEED

C9orf78

81

Q9NZ63
EEKRKEEEQREIKKE

UBXN4

211

Q92575
EAAKEKKKEDDDGEI

ZC3H18

181

Q86VM9
KENEREGEKREEEKE

PPP1R12A

816

O14974
VGKGEQKEEEEKEVK

NEFM

696

P07197