Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent protein disaggregase activity	HSPA1A HSPA1B HSPA8	8.20e-08	6	33	3	GO:0140545
GeneOntologyMolecularFunction	C3HC4-type RING finger domain binding	HSPA1A HSPA1B HSPA8	8.20e-08	6	33	3	GO:0055131
GeneOntologyMolecularFunction	protein-containing complex destabilizing activity	HSPA1A HSPA1B HSPA8	1.85e-06	15	33	3	GO:0140776
GeneOntologyMolecularFunction	denatured protein binding	HSPA1A HSPA1B	7.94e-06	3	33	2	GO:0031249
GeneOntologyMolecularFunction	death receptor agonist activity	HSPA1A HSPA1B	2.64e-05	5	33	2	GO:0038177
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSPA1A HSPA1B HSPA8	3.90e-05	40	33	3	GO:0140662
GeneOntologyMolecularFunction	protein folding chaperone	HSPA1A HSPA1B HSPA8	2.36e-04	73	33	3	GO:0044183
GeneOntologyMolecularFunction	virus receptor activity	HSPA1A HSPA1B ITGB7	3.70e-04	85	33	3	GO:0001618
GeneOntologyMolecularFunction	exogenous protein binding	HSPA1A HSPA1B ITGB7	3.83e-04	86	33	3	GO:0140272
GeneOntologyMolecularFunction	misfolded protein binding	HSPA1A HSPA1B	3.99e-04	18	33	2	GO:0051787
GeneOntologyMolecularFunction	death receptor activity	HSPA1A HSPA1B	5.45e-04	21	33	2	GO:0005035
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF27 HSPA1A HSPA1B DHX34 HSPA8	7.32e-04	441	33	5	GO:0016887
GeneOntologyMolecularFunction	unfolded protein binding	HSPA1A HSPA1B HSPA8	1.17e-03	126	33	3	GO:0051082
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	HSPA1A HSPA1B	1.61e-03	36	33	2	GO:0140416
GeneOntologyMolecularFunction	NF-kappaB binding	HSPA1A HSPA1B	1.61e-03	36	33	2	GO:0051059
GeneOntologyMolecularFunction	disordered domain specific binding	HSPA1A HSPA1B	1.89e-03	39	33	2	GO:0097718
GeneOntologyMolecularFunction	heat shock protein binding	HSPA1A HSPA1B HSPA8	2.43e-03	163	33	3	GO:0031072
GeneOntologyMolecularFunction	ATP-dependent activity	KIF27 HSPA1A HSPA1B DHX34 HSPA8	3.15e-03	614	33	5	GO:0140657
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	MAPK9 FAM20A NEK8 POLR3A EPHA8 REV1	3.94e-03	938	33	6	GO:0016772
GeneOntologyBiologicalProcess	protein refolding	HSPA1A HSPA1B HSPA8	1.21e-05	30	31	3	GO:0042026
GeneOntologyBiologicalProcess	chaperone cofactor-dependent protein refolding	HSPA1A HSPA1B HSPA8	1.95e-05	35	31	3	GO:0051085
GeneOntologyBiologicalProcess	'de novo' post-translational protein folding	HSPA1A HSPA1B HSPA8	3.15e-05	41	31	3	GO:0051084
GeneOntologyBiologicalProcess	cellular heat acclimation	HSPA1A HSPA1B	3.27e-05	6	31	2	GO:0070370
GeneOntologyBiologicalProcess	'de novo' protein folding	HSPA1A HSPA1B HSPA8	4.47e-05	46	31	3	GO:0006458
GeneOntologyBiologicalProcess	heat acclimation	HSPA1A HSPA1B	4.57e-05	7	31	2	GO:0010286
GeneOntologyBiologicalProcess	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	HSPA1A HSPA1B	4.57e-05	7	31	2	GO:0070434
GeneOntologyBiologicalProcess	positive regulation of microtubule nucleation	HSPA1A HSPA1B	6.09e-05	8	31	2	GO:0090063
GeneOntologyBiologicalProcess	positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	HSPA1A HSPA1B	6.09e-05	8	31	2	GO:0070426
GeneOntologyBiologicalProcess	lysosomal transport	VPS41 HSPA1A HSPA1B HSPA8	7.45e-05	151	31	4	GO:0007041
GeneOntologyBiologicalProcess	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	HSPA1A HSPA1B	1.19e-04	11	31	2	GO:0070432
GeneOntologyBiologicalProcess	negative regulation of inclusion body assembly	HSPA1A HSPA1B	1.43e-04	12	31	2	GO:0090084
GeneOntologyBiologicalProcess	vacuolar transport	VPS41 HSPA1A HSPA1B HSPA8	1.70e-04	187	31	4	GO:0007034
GeneOntologyBiologicalProcess	positive regulation of tumor necrosis factor-mediated signaling pathway	HSPA1A HSPA1B	1.97e-04	14	31	2	GO:1903265
GeneOntologyBiologicalProcess	chaperone-mediated protein folding	HSPA1A HSPA1B HSPA8	2.34e-04	80	31	3	GO:0061077
GeneOntologyBiologicalProcess	cellular response to heat	HSPA1A HSPA1B HSPA8	2.42e-04	81	31	3	GO:0034605
GeneOntologyBiologicalProcess	regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	HSPA1A HSPA1B	2.59e-04	16	31	2	GO:0070424
GeneOntologyBiologicalProcess	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	MAPK9 HSPA1A HSPA1B	2.79e-04	85	31	3	GO:0032436
GeneOntologyBiologicalProcess	regulation of microtubule nucleation	HSPA1A HSPA1B	3.68e-04	19	31	2	GO:0010968
GeneOntologyBiologicalProcess	nucleotide-binding oligomerization domain containing 2 signaling pathway	HSPA1A HSPA1B	4.08e-04	20	31	2	GO:0070431
GeneOntologyBiologicalProcess	regulation of inclusion body assembly	HSPA1A HSPA1B	4.51e-04	21	31	2	GO:0090083
GeneOntologyBiologicalProcess	regulation of mitotic spindle assembly	HSPA1A HSPA1B	5.91e-04	24	31	2	GO:1901673
GeneOntologyBiologicalProcess	positive regulation of ubiquitin-dependent protein catabolic process	MAPK9 HSPA1A HSPA1B	6.60e-04	114	31	3	GO:2000060
GeneOntologyBiologicalProcess	response to oxidative stress	TXNRD2 MAPK9 HSPA1A HSPA1B HSPA8	6.76e-04	478	31	5	GO:0006979
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	VPS41 MAPK9 HSPA1A HSPA1B HSPA8	7.49e-04	489	31	5	GO:0043254
GeneOntologyBiologicalProcess	response to heat	HSPA1A HSPA1B HSPA8	7.85e-04	121	31	3	GO:0009408
GeneOntologyBiologicalProcess	positive regulation of proteasomal protein catabolic process	MAPK9 HSPA1A HSPA1B	8.23e-04	123	31	3	GO:1901800
GeneOntologyBiologicalProcess	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	HSPA1A HSPA1B	9.26e-04	30	31	2	GO:0035872
GeneOntologyBiologicalProcess	regulation of cytoplasmic pattern recognition receptor signaling pathway	HSPA1A HSPA1B HSPA8	9.45e-04	129	31	3	GO:0039531
GeneOntologyBiologicalProcess	cellular response to oxidative stress	MAPK9 HSPA1A HSPA1B HSPA8	9.51e-04	295	31	4	GO:0034599
GeneOntologyBiologicalProcess	inclusion body assembly	HSPA1A HSPA1B	1.12e-03	33	31	2	GO:0070841
GeneOntologyBiologicalProcess	regulation of proteasomal ubiquitin-dependent protein catabolic process	MAPK9 HSPA1A HSPA1B	1.17e-03	139	31	3	GO:0032434
GeneOntologyBiologicalProcess	regulation of spindle assembly	HSPA1A HSPA1B	1.19e-03	34	31	2	GO:0090169
GeneOntologyBiologicalProcess	positive regulation of proteolysis involved in protein catabolic process	MAPK9 HSPA1A HSPA1B	1.40e-03	148	31	3	GO:1903052
GeneOntologyBiologicalProcess	positive regulation of microtubule polymerization	HSPA1A HSPA1B	1.41e-03	37	31	2	GO:0031116
GeneOntologyBiologicalProcess	positive regulation of erythrocyte differentiation	HSPA1A HSPA1B	1.41e-03	37	31	2	GO:0045648
GeneOntologyBiologicalProcess	viral life cycle	HSPA1A HSPA1B ITGB7 HSPA8	1.61e-03	340	31	4	GO:0019058
GeneOntologyBiologicalProcess	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	HSPA1A HSPA1B	1.65e-03	40	31	2	GO:2001240
GeneOntologyBiologicalProcess	negative regulation of signal transduction in absence of ligand	HSPA1A HSPA1B	1.65e-03	40	31	2	GO:1901099
GeneOntologyBiologicalProcess	biological process involved in symbiotic interaction	HSPA1A HSPA1B ITGB7 HSPA8	1.80e-03	351	31	4	GO:0044403
GeneOntologyBiologicalProcess	positive regulation of microtubule polymerization or depolymerization	HSPA1A HSPA1B	1.81e-03	42	31	2	GO:0031112
GeneOntologyBiologicalProcess	positive regulation of T cell mediated cytotoxicity	CD1A HSPA8	1.81e-03	42	31	2	GO:0001916
GeneOntologyBiologicalProcess	cellular response to cadmium ion	MAPK9 HSPA8	1.90e-03	43	31	2	GO:0071276
GeneOntologyBiologicalProcess	regulation of mitotic spindle organization	HSPA1A HSPA1B	1.99e-03	44	31	2	GO:0060236
GeneOntologyBiologicalProcess	symbiont entry into host cell	HSPA1A HSPA1B ITGB7	2.05e-03	169	31	3	GO:0046718
GeneOntologyBiologicalProcess	symbiont entry into host	HSPA1A HSPA1B ITGB7	2.30e-03	176	31	3	GO:0044409
GeneOntologyBiologicalProcess	cellular response to chemical stress	MAPK9 HSPA1A HSPA1B HSPA8	2.34e-03	377	31	4	GO:0062197
GeneOntologyBiologicalProcess	regulation of spindle organization	HSPA1A HSPA1B	2.36e-03	48	31	2	GO:0090224
GeneOntologyBiologicalProcess	protein targeting to vacuole	VPS41 HSPA8	2.46e-03	49	31	2	GO:0006623
GeneOntologyBiologicalProcess	positive regulation of membrane permeability	HSPA1A HSPA8	2.56e-03	50	31	2	GO:1905710
GeneOntologyBiologicalProcess	positive regulation of proteolysis	MAPK9 HSPA1A HSPA1B HSPA8	2.64e-03	390	31	4	GO:0045862
GeneOntologyBiologicalProcess	regulation of ubiquitin-dependent protein catabolic process	MAPK9 HSPA1A HSPA1B	2.65e-03	185	31	3	GO:2000058
GeneOntologyBiologicalProcess	cytoplasmic pattern recognition receptor signaling pathway	HSPA1A HSPA1B HSPA8	2.78e-03	188	31	3	GO:0002753
GeneOntologyBiologicalProcess	regulation of T cell mediated cytotoxicity	CD1A HSPA8	2.87e-03	53	31	2	GO:0001914
GeneOntologyBiologicalProcess	regulation of extrinsic apoptotic signaling pathway in absence of ligand	HSPA1A HSPA1B	2.98e-03	54	31	2	GO:2001239
GeneOntologyBiologicalProcess	regulation of pattern recognition receptor signaling pathway	HSPA1A HSPA1B HSPA8	2.99e-03	193	31	3	GO:0062207
GeneOntologyBiologicalProcess	microtubule nucleation	HSPA1A HSPA1B	3.31e-03	57	31	2	GO:0007020
Domain	HSP70	HSPA1A HSPA1B HSPA8	2.52e-06	16	32	3	PF00012
Domain	HSP70_2	HSPA1A HSPA1B HSPA8	3.06e-06	17	32	3	PS00329
Domain	HSP70_3	HSPA1A HSPA1B HSPA8	3.06e-06	17	32	3	PS01036
Domain	HSP70_1	HSPA1A HSPA1B HSPA8	3.06e-06	17	32	3	PS00297
Domain	Hsp_70_fam	HSPA1A HSPA1B HSPA8	3.66e-06	18	32	3	IPR013126
Domain	TIL	MUC5B FCGBP	1.86e-04	12	32	2	PF01826
Domain	-	HSPA1A HSPA8	1.86e-04	12	32	2	2.60.34.10
Domain	HSP70_peptide-bd	HSPA1A HSPA8	1.86e-04	12	32	2	IPR029047
Domain	C8	MUC5B FCGBP	1.86e-04	12	32	2	PF08742
Domain	-	HSPA1A HSPA8	2.19e-04	13	32	2	1.20.1270.10
Domain	Unchr_dom_Cys-rich	MUC5B FCGBP	2.19e-04	13	32	2	IPR014853
Domain	Heat_shock_70_CS	HSPA1A HSPA8	2.19e-04	13	32	2	IPR018181
Domain	HSP70_C	HSPA1A HSPA8	2.19e-04	13	32	2	IPR029048
Domain	C8	MUC5B FCGBP	2.19e-04	13	32	2	SM00832
Domain	TIL_dom	MUC5B FCGBP	2.55e-04	14	32	2	IPR002919
Domain	VWFD	MUC5B FCGBP	3.36e-04	16	32	2	PS51233
Domain	VWD	MUC5B FCGBP	3.36e-04	16	32	2	SM00216
Domain	VWF_type-D	MUC5B FCGBP	3.36e-04	16	32	2	IPR001846
Domain	VWD	MUC5B FCGBP	3.36e-04	16	32	2	PF00094
Domain	VWC_out	MUC5B FCGBP	4.78e-04	19	32	2	SM00215
Domain	VWC	MUC5B FCGBP	1.92e-03	38	32	2	SM00214
Domain	VWF_dom	MUC5B FCGBP	2.35e-03	42	32	2	IPR001007
Domain	EGF_extracell	ITGB7 ADAM22	4.73e-03	60	32	2	IPR013111
Domain	EGF_2	ITGB7 ADAM22	4.73e-03	60	32	2	PF07974
Domain	TPR-like_helical_dom	VPS41 TRAPPC10 TRANK1	7.28e-03	233	32	3	IPR011990
Domain	EGF-like_CS	ITGB7 ADAM22 EPHA8	9.92e-03	261	32	3	IPR013032
Pathway	REACTOME_ATTENUATION_PHASE	HSPA1A HSPA1B HSPA8	1.23e-06	13	24	3	MM14952
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSPA1A HSPA1B HSPA8	7.51e-06	23	24	3	MM14953
Pathway	REACTOME_ATTENUATION_PHASE	HSPA1A HSPA1B HSPA8	1.38e-05	28	24	3	M27254
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSPA1A HSPA1B HSPA8	3.52e-05	38	24	3	M27255
Pathway	WP_MEASLES_VIRUS_INFECTION	MAPK9 HSPA1A HSPA1B HSPA8	7.58e-05	136	24	4	M42547
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	HSPA1A HSPA1B HSPA8	9.07e-05	52	24	3	MM14949
Pathway	REACTOME_AUF1_HNRNP_D0_BINDS_AND_DESTABILIZES_MRNA	HSPA1A HSPA1B HSPA8	1.07e-04	55	24	3	MM15137
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	HSPA1A HSPA1B HSPA8	1.19e-04	57	24	3	M27251
Pathway	WP_MAPK_SIGNALING_PATHWAY	MAPK9 HSPA1A HSPA1B HSPA8	1.42e-04	160	24	4	MM15990
Pathway	REACTOME_PKR_MEDIATED_SIGNALING	HSPA1A HSPA1B HSPA8	1.85e-04	66	24	3	MM17074
Pathway	WP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY	HSPA1A HSPA1B HSPA8	2.30e-04	71	24	3	M39690
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	HSPA1A HSPA1B HSPA8	2.49e-04	73	24	3	MM14948
Pathway	REACTOME_PKR_MEDIATED_SIGNALING	HSPA1A HSPA1B HSPA8	2.81e-04	76	24	3	M48037
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	HSPA1A HSPA1B HSPA8	3.52e-04	82	24	3	M27250
Pathway	REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS	HSPA1A HSPA1B HSPA8	4.04e-04	86	24	3	MM15140
Pathway	WP_APOPTOSIS_MODULATION_BY_HSP70	HSPA1A HSPA1B	4.18e-04	18	24	2	MM15964
Pathway	KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	HSPA1A HSPA1B HSPA8	4.33e-04	88	24	3	M16004
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	HSPA1A HSPA1B HSPA8	4.93e-04	92	24	3	MM14951
Pathway	REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES	HSPA1A HSPA1B HSPA8	5.25e-04	94	24	3	MM14515
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	HSPA1A HSPA1B HSPA8	6.48e-04	101	24	3	M27253
Pathway	WP_MAPK_SIGNALING	MAPK9 HSPA1A HSPA1B HSPA8	7.30e-04	246	24	4	M39597
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	MAPK9 HSPA1A HSPA1B HSPA8	9.92e-04	267	24	4	M10792
Pathway	REACTOME_HSF1_ACTIVATION	HSPA1A HSPA1B	1.25e-03	31	24	2	M27252
Pathway	KEGG_SPLICEOSOME	HSPA1A HSPA1B HSPA8	1.26e-03	127	24	3	M2044
Pathway	REACTOME_CELLULAR_RESPONSES_TO_STIMULI	TXNRD2 MAPK9 HSPA1A HSPA1B HSPA8	1.40e-03	505	24	5	MM15548
Pathway	REACTOME_INTERFERON_SIGNALING	HSPA1A HSPA1B HSPA8	1.60e-03	138	24	3	MM15635
Pathway	REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES	HSPA1A HSPA1B HSPA8	2.07e-03	151	24	3	M550
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	MUC5B GSDME MAPK9 HSPA1A HSPA1B HSPA8 POLR3A	2.12e-03	1128	24	7	M1036
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	MAPK9 ITGB7	2.87e-03	47	24	2	M39829
Pubmed	Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.	HSPA1A HSPA1B HSPA8	8.54e-10	3	34	3	23352621
Pubmed	Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.	HSPA1A HSPA1B HSPA8	8.54e-10	3	34	3	15129916
Pubmed	Functional analysis of HSPA1A and HSPA8 in parturition.	HSPA1A HSPA1B HSPA8	8.54e-10	3	34	3	28025138
Pubmed	Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.	HSPA1A HSPA1B HSPA8	3.41e-09	4	34	3	22956628
Pubmed	Upregulation of the constitutively expressed HSC70 by KLF4.	HSPA1A HSPA1B HSPA8	3.41e-09	4	34	3	18379898
Pubmed	Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.	HSPA1A HSPA1B HSPA8	3.41e-09	4	34	3	18299791
Pubmed	Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.	HSPA1A HSPA1B HSPA8	8.52e-09	5	34	3	16906134
Pubmed	A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.	HSPA1A HSPA1B HSPA8	8.52e-09	5	34	3	11584023
Pubmed	HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.	HSPA1A HSPA1B HSPA8	8.52e-09	5	34	3	17182002
Pubmed	BAG-1 modulates the chaperone activity of Hsp70/Hsc70.	HSPA1A HSPA1B HSPA8	1.70e-08	6	34	3	9305631
Pubmed	Heat shock factor 2 is activated during mouse heart development.	HSPA1A HSPA1B HSPA8	1.70e-08	6	34	3	11032181
Pubmed	RING finger protein RNF207, a novel regulator of cardiac excitation.	HSPA1A HSPA1B HSPA8	1.70e-08	6	34	3	25281747
Pubmed	Genetic aspects of the hsp70 multigene family in vertebrates.	HSPA1A HSPA1B HSPA8	1.70e-08	6	34	3	7988674
Pubmed	Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.	HSPA1A HSPA1B HSPA8	1.70e-08	6	34	3	15963462
Pubmed	Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.	HSPA1A HSPA1B HSPA8	2.98e-08	7	34	3	10205060
Pubmed	Function and regulation of heat shock factor 2 during mouse embryogenesis.	HSPA1A HSPA1B HSPA8	4.76e-08	8	34	3	9122205
Pubmed	Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.	HSPA1A HSPA1B HSPA8	7.14e-08	9	34	3	21763498
Pubmed	Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.	HSPA1A HSPA1B HSPA8	1.02e-07	10	34	3	23921388
Pubmed	Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.	HSPA1A HSPA1B HSPA8	1.02e-07	10	34	3	7906708
Pubmed	Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.	HSPA1A HSPA1B HSPA8	1.02e-07	10	34	3	11932435
Pubmed	gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.	HSPA1A HSPA1B HSPA8	1.02e-07	10	34	3	12832005
Pubmed	ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.	HSPA1A HSPA1B HSPA8	1.40e-07	11	34	3	27708256
Pubmed	Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.	HSPA1A HSPA1B HSPA8	1.40e-07	11	34	3	24318877
Pubmed	HIV-1 viral protein R (Vpr) and its interactions with host cell.	HSPA1A HSPA1B HSPA8	1.87e-07	12	34	3	19275587
Pubmed	CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.	HSPA1A HSPA1B HSPA8	1.87e-07	12	34	3	12150907
Pubmed	Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.	MAPK9 HSPA1A HSPA1B	1.87e-07	12	34	3	18385140
Pubmed	A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.	HSPA1A HSPA1B HSPA8	2.42e-07	13	34	3	30792309
Pubmed	UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.	HSPA1A HSPA1B HSPA8	2.42e-07	13	34	3	27477512
Pubmed	Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.	HSPA1A HSPA1B HSPA8	3.85e-07	15	34	3	10964507
Pubmed	Clathrin facilitates the morphogenesis of retrovirus particles.	HSPA1A HSPA1B HSPA8	4.74e-07	16	34	3	21738476
Pubmed	Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.	HSPA1A HSPA1B	9.28e-07	2	34	2	12411538
Pubmed	Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.	HSPA1A HSPA1B	9.28e-07	2	34	2	2868009
Pubmed	Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.	HSPA1A HSPA1B	9.28e-07	2	34	2	25618331
Pubmed	Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.	HSPA1A HSPA1B	9.28e-07	2	34	2	24328534
Pubmed	In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	3786141
Pubmed	The role of heat shock protein 70 in mediating age-dependent mortality in sepsis.	HSPA1A HSPA1B	9.28e-07	2	34	2	21296977
Pubmed	Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.	HSPA1A HSPA1B	9.28e-07	2	34	2	16679378
Pubmed	The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages.	HSPA1A HSPA1B	9.28e-07	2	34	2	17617616
Pubmed	Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.	HSPA1A HSPA1B	9.28e-07	2	34	2	19639652
Pubmed	Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.	HSPA1A HSPA1B	9.28e-07	2	34	2	26448330
Pubmed	Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	29323151
Pubmed	HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.	HSPA1A HSPA1B	9.28e-07	2	34	2	12714332
Pubmed	Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.	HSPA1A HSPA1B	9.28e-07	2	34	2	19299581
Pubmed	Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.	HSPA1A HSPA1B	9.28e-07	2	34	2	11713291
Pubmed	Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.	HSPA1A HSPA1B	9.28e-07	2	34	2	21108992
Pubmed	The septic shock associated HSPA1B1267 polymorphism influences production of HSPA1A and HSPA1B.	HSPA1A HSPA1B	9.28e-07	2	34	2	15232679
Pubmed	Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.	HSPA1A HSPA1B	9.28e-07	2	34	2	16100242
Pubmed	Role of the C-terminal region of mouse inducible Hsp72 in the recognition of peptide substrate for chaperone activity.	HSPA1A HSPA1B	9.28e-07	2	34	2	15498567
Pubmed	Biological activity of truncated C-terminus human heat shock protein 72.	HSPA1A HSPA1B	9.28e-07	2	34	2	21094186
Pubmed	Processing of U14 small nucleolar RNA from three different introns of the mouse 70-kDa-cognate-heat-shock-protein pre-messenger RNA.	HSPA1B HSPA8	9.28e-07	2	34	2	7813466
Pubmed	Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.	HSPA1A HSPA1B	9.28e-07	2	34	2	26923070
Pubmed	Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).	HSPA1A HSPA1B	9.28e-07	2	34	2	31320473
Pubmed	Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.	HSPA1A HSPA8	9.28e-07	2	34	2	18772114
Pubmed	Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors.	HSPA1A HSPA1B	9.28e-07	2	34	2	38703814
Pubmed	Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.	HSPA1A HSPA1B	9.28e-07	2	34	2	16482515
Pubmed	Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	17482577
Pubmed	Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.	HSPA1A HSPA1B	9.28e-07	2	34	2	23812373
Pubmed	Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.	HSPA1A HSPA1B	9.28e-07	2	34	2	19605647
Pubmed	Differential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions.	HSPA1B HSPA8	9.28e-07	2	34	2	12114509
Pubmed	Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.	HSPA1A HSPA1B	9.28e-07	2	34	2	11864979
Pubmed	Structure and expression of an inducible HSP70-encoding gene from Mus musculus.	HSPA1A HSPA1B	9.28e-07	2	34	2	8076831
Pubmed	The 70 kDa heat shock protein protects against experimental traumatic brain injury.	HSPA1A HSPA1B	9.28e-07	2	34	2	23816752
Pubmed	hsp72, a host determinant of measles virus neurovirulence.	HSPA1A HSPA1B	9.28e-07	2	34	2	16971451
Pubmed	Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.	HSPA1A HSPA1B	9.28e-07	2	34	2	15719414
Pubmed	Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.	HSPA1A HSPA1B	9.28e-07	2	34	2	26976620
Pubmed	Human immunodeficiency virus-1 Nef suppresses Hsp70-mediated Tat activation.	HSPA1A HSPA1B	9.28e-07	2	34	2	21970979
Pubmed	Induction of heat shock protein 70 inhibits ischemic renal injury.	HSPA1A HSPA1B	9.28e-07	2	34	2	21270764
Pubmed	[Relationship between heat stress protein 70 gene polymorphisms and the risk of acute mountain sickness].	HSPA1A HSPA1B	9.28e-07	2	34	2	15748471
Pubmed	Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.	HSPA1A HSPA1B	9.28e-07	2	34	2	21187371
Pubmed	Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.	HSPA1A HSPA1B	9.28e-07	2	34	2	20849898
Pubmed	Heat shock protein 70 promotes lipogenesis in HepG2 cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	29631603
Pubmed	Coordinated post-transcriptional regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation.	HSPA1A HSPA1B	9.28e-07	2	34	2	21757701
Pubmed	Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer.	HSPA1A HSPA1B	9.28e-07	2	34	2	19005184
Pubmed	Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.	HSPA1A HSPA1B	9.28e-07	2	34	2	20430459
Pubmed	Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.	HSPA1A HSPA1B	9.28e-07	2	34	2	20235222
Pubmed	Genetic determinants of HSP70 gene expression following heat shock.	HSPA1A HSPA1B	9.28e-07	2	34	2	20876613
Pubmed	Role of membrane Hsp70 in radiation sensitivity of tumor cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	26197988
Pubmed	The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.	HSPA1A HSPA1B	9.28e-07	2	34	2	20223214
Pubmed	Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.	HSPA1A HSPA1B	9.28e-07	2	34	2	16361353
Pubmed	Association between heat shock protein 72 gene polymorphism and acute renal failure in premature neonates.	HSPA1A HSPA8	9.28e-07	2	34	2	12840151
Pubmed	Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.	HSPA1A HSPA1B	9.28e-07	2	34	2	17234954
Pubmed	Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.	HSPA1A HSPA1B	9.28e-07	2	34	2	22792201
Pubmed	Structure of a new crystal form of human Hsp70 ATPase domain.	HSPA1A HSPA1B	9.28e-07	2	34	2	10216320
Pubmed	Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	20093776
Pubmed	Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.	HSPA1A HSPA1B	9.28e-07	2	34	2	23704948
Pubmed	Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.	HSPA1A HSPA1B	9.28e-07	2	34	2	3931075
Pubmed	Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic.	HSPA1A HSPA1B	9.28e-07	2	34	2	9820195
Pubmed	Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.	HSPA1A HSPA1B	9.28e-07	2	34	2	19157555
Pubmed	Tumor necrosis factor alpha and inflammation disrupt the polarity complex in intestinal epithelial cells by a posttranslational mechanism.	HSPA1A HSPA1B	9.28e-07	2	34	2	21135124
Pubmed	Effects of voluntary exercise and genetic selection for high activity levels on HSP72 expression in house mice.	HSPA1A HSPA1B	9.28e-07	2	34	2	14672969
Pubmed	Structure and expression of the human gene encoding major heat shock protein HSP70.	HSPA1A HSPA1B	9.28e-07	2	34	2	2858050
Pubmed	Regulation of hsp70 mRNA levels during oocyte maturation and zygotic gene activation in the mouse.	HSPA1B HSPA8	9.28e-07	2	34	2	2010034
Pubmed	Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.	HSPA1A HSPA1B	9.28e-07	2	34	2	37298493
Pubmed	Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.	HSPA1A HSPA1B	9.28e-07	2	34	2	17513788
Pubmed	Heat-shock protein 70 genes and human longevity: a view from Denmark.	HSPA1A HSPA1B	9.28e-07	2	34	2	16804002
Pubmed	IL-6 activates HSP72 gene expression in human skeletal muscle.	HSPA1A HSPA1B	9.28e-07	2	34	2	12207910
Pubmed	Genetic Modulation of HSPA1A Accelerates Kindling Progression and Exerts Pro-convulsant Effects.	HSPA1A HSPA1B	9.28e-07	2	34	2	29964156
Pubmed	Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.	HSPA1A HSPA1B	9.28e-07	2	34	2	16735677
Pubmed	Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.	HSPA1A HSPA1B	9.28e-07	2	34	2	28837204
Pubmed	Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia.	HSPA1A HSPA1B	9.28e-07	2	34	2	3019832
Interaction	CCDC117 interactions	HSPA1A HSPA1B HSPA8	8.37e-06	26	31	3	int:CCDC117
Interaction	PDLIM4 interactions	PTPN13 HSPA1A HSPA8	9.40e-06	27	31	3	int:PDLIM4
Interaction	BMX interactions	HSPA1A HSPA8 ARIH2 EPHA8	1.07e-05	90	31	4	int:BMX
Interaction	METTL21A interactions	HSPA1A HSPA1B HSPA8	2.27e-05	36	31	3	int:METTL21A
Interaction	FAM83F interactions	HSPA1A HSPA1B HSPA8	2.27e-05	36	31	3	int:FAM83F
Interaction	PPP1R15A interactions	HSPA1A HSPA8 POLR3A	3.13e-05	40	31	3	int:PPP1R15A
Interaction	RNF207 interactions	HSPA1A HSPA8	4.79e-05	7	31	2	int:RNF207
Interaction	TRIM38 interactions	HSPA1A HSPA1B HSPA8	5.10e-05	47	31	3	int:TRIM38
Interaction	TSSK6 interactions	HSPA1A HSPA8 POLR3A	5.10e-05	47	31	3	int:TSSK6
Interaction	HEY1 interactions	PTPN13 HSPA1A HSPA1B HSPA8	6.07e-05	140	31	4	int:HEY1
Interaction	LGALS3BP interactions	TRAPPC10 HSPA1A HSPA8 ARIH2 EPHA8	6.98e-05	286	31	5	int:LGALS3BP
Interaction	CCNI2 interactions	HSPA1B HSPA8	8.19e-05	9	31	2	int:CCNI2
Interaction	HSPA1B interactions	HSPA1A HSPA1B NEK8 ARIH2 EPHA8	8.88e-05	301	31	5	int:HSPA1B
Interaction	CCDC142 interactions	HSPA1B HSPA8	1.02e-04	10	31	2	int:CCDC142
Interaction	DNAI1 interactions	KIF27 HSPA8	1.25e-04	11	31	2	int:DNAI1
Interaction	ENDOG interactions	HSPA1A HSPA8 EPHA8	1.75e-04	71	31	3	int:ENDOG
Interaction	LRRC28 interactions	HSPA1B HSPA8	1.77e-04	13	31	2	int:LRRC28
Interaction	LRRC56 interactions	MAPK9 HSPA8	1.77e-04	13	31	2	int:LRRC56
Interaction	CFAP52 interactions	HSPA1A HSPA8	1.77e-04	13	31	2	int:CFAP52
Interaction	NNMT interactions	HSPA1A HSPA8	2.06e-04	14	31	2	int:NNMT
Interaction	RAPGEF6 interactions	PTPN13 HSPA1A HSPA8	2.32e-04	78	31	3	int:RAPGEF6
Interaction	FCGBP interactions	FCGBP HSPA8	2.37e-04	15	31	2	int:FCGBP
Interaction	CYP2W1 interactions	HSPA1B HSPA8	2.37e-04	15	31	2	int:CYP2W1
Interaction	C3orf38 interactions	HSPA1A HSPA8	3.07e-04	17	31	2	int:C3orf38
Interaction	TECPR2 interactions	VPS41 HSPA8	3.07e-04	17	31	2	int:TECPR2
Interaction	S100A11 interactions	HSPA1A HSPA8 NEK8	3.09e-04	86	31	3	int:S100A11
Interaction	CNTNAP1 interactions	HSPA1A HSPA1B HSPA8	3.20e-04	87	31	3	int:CNTNAP1
Interaction	ILRUN interactions	HSPA1A HSPA8	3.45e-04	18	31	2	int:ILRUN
Cytoband	3q25.1	MED12L MINDY4B	2.77e-04	33	34	2	3q25.1
GeneFamily	Heat shock 70kDa proteins	HSPA1A HSPA1B HSPA8	1.57e-06	17	25	3	583
Coexpression	KRISHNAN_FURIN_TARGETS_UP	HSPA1A HSPA1B HSPA8	1.97e-07	10	32	3	MM1243
Coexpression	DEN_INTERACT_WITH_LCA5	HSPA1A HSPA1B HSPA8	4.22e-06	26	32	3	M1380
Coexpression	DAUER_STAT3_TARGETS_DN	TRANK1 HSPA1A HSPA1B	2.75e-05	48	32	3	M13696
Coexpression	AIZARANI_LIVER_C12_NK_NKT_CELLS_4	HSPA1A HSPA1B HSPA8	2.93e-05	49	32	3	M39116
Coexpression	JINESH_BLEBBISHIELD_TRANSFORMED_STEM_CELL_SPHERES_UP	GSDME HSPA1A HSPA1B HSPA8	5.33e-05	170	32	4	M38971
Coexpression	KRISHNAN_FURIN_TARGETS_UP	HSPA1A HSPA8	6.46e-05	10	32	2	M15228
Coexpression	GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN	PTPN13 MAPK9 HSPA1A POLR3A	1.00e-04	200	32	4	M3866
Coexpression	GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN	TRAPPC10 MAPK9 ARIH2 REV1	1.00e-04	200	32	4	M7372
Coexpression	FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_UP	HSPA1A HSPA1B	1.71e-04	16	32	2	MM559
ToppCell	Mild_COVID-19-Myeloid-MoAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	GSDME FAM20A HSPA1A HSPA1B	6.90e-06	162	34	4	e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HSPA1A HSPA1B HSPA8 REV1	9.79e-06	177	34	4	3d1b142aa2bd18df14816abaca356596b297394e
ToppCell	Severe-CD4+_T_activated\|Severe / Disease group and Cell class	TRANK1 HSPA1A HSPA1B HSPA8	9.79e-06	177	34	4	a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell	Severe-CD4+_T_activated\|World / Disease group and Cell class	TRANK1 HSPA1A HSPA1B HSPA8	1.00e-05	178	34	4	ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell	IPF-Myeloid-DC_Langerhans\|World / Disease state, Lineage and Cell class	MED12L CD1A GSDME FCGBP	1.09e-05	182	34	4	0e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A ADAM22	1.27e-05	189	34	4	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	TMEM132C HSPA1A HSPA1B ADAM22	1.29e-05	190	34	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A ADAM22	1.29e-05	190	34	4	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HSPA1A HSPA1B ITGB7 HSPA8	1.46e-05	196	34	4	d79a84aa25ba70483ae899cd5b52ba0bbffdcd7b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	HSPA1A HSPA1B HSPA8 AKAP7	1.49e-05	197	34	4	a97556e9fbb24272de51f54ecda6ab9ccb97a61e
ToppCell	(2)_MNPs-(2)_Dendritic_Cells\|(2)_MNPs / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	CD1A FCGBP ITGB7 HSPA8	1.52e-05	198	34	4	4c1f155298b7d0afddfeb2744b369a1ffd823916
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	FAM20A HSPA1A HSPA1B HSPA8	1.55e-05	199	34	4	0d1f2b0d10c1f8ee10c448659b2a22ea0a6a6f0d
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CD1A HSPA1A HSPA1B	3.23e-05	81	34	3	8cb94dda18010b3b05e5ab72235850483013c03a
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPA1A HSPA1B NEK8	2.01e-04	150	34	3	57f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCell	Adult-Immune-enucleated_erythrocyte-D175\|Adult / Lineage, Cell type, age group and donor	HSPA1A HSPA1B HSPA8	2.09e-04	152	34	3	530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA1A ITGB7 ADAM22	2.09e-04	152	34	3	7e686721b95c837f2b0d5116927c8ecacef055ee
ToppCell	facs-MAT-Fat-24m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAPPC10 TRANK1 TXNRD2	2.09e-04	152	34	3	fa03262e2853b7d35ef8cdbb652930abad90563c
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM20A HSPA1A HSPA1B	2.14e-04	153	34	3	5fbb90b8477f9fdabf3be19efd3068fbf70abee6
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAM20A HSPA1A HSPA1B	2.14e-04	153	34	3	2c46183481e6d5a7fa190a743062509465f88e56
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM20A HSPA1A HSPA1B	2.14e-04	153	34	3	decc4f3098a9374a6b65c015a9d36380986290bf
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM20A HSPA1A HSPA1B	2.14e-04	153	34	3	36a28805c0545c2f410c74a6ca0a70d840e75715
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HSPA1A HSPA1B ZNF641	2.22e-04	155	34	3	c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 DHX34 ADAM22	2.30e-04	157	34	3	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 DHX34 ITGB7	2.39e-04	159	34	3	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	343B-Myeloid-Mast_cell-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD300LD-AS1 HSPA1A HSPA1B	2.44e-04	160	34	3	a2f09b5955602819c8978f4372130c8ef915cd07
ToppCell	343B-Myeloid-Mast_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD300LD-AS1 HSPA1A HSPA1B	2.44e-04	160	34	3	133ecae0a894d9a0d49d58859623359096b6f030
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 HSPA1A HSPA1B	2.48e-04	161	34	3	140b3c7077947c541cff54f6754e2df968345f4d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 HSPA1A HSPA1B	2.53e-04	162	34	3	16f9fbcaa0093ffc5a2a5e32db6040e2cb519d47
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	HSPA1A HSPA1B HSPA8	2.57e-04	163	34	3	93bc67a13267c858cabc81eafe1c9b966d872a9e
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	2.67e-04	165	34	3	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	2.67e-04	165	34	3	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HSPA1A HSPA1B HSPA8	2.67e-04	165	34	3	3c8baed838eccb6e720bacb7458f087647dc1222
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	2.67e-04	165	34	3	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 HSPA1A HSPA1B	2.76e-04	167	34	3	e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPA1A ITGB7 HSPA8	2.81e-04	168	34	3	696b31bedbc7d40817a733e8c6ec2633404be619
ToppCell	Adult-Immune-enucleated_erythrocyte-D122\|Adult / Lineage, Cell type, age group and donor	TMEM132C HSPA1A HSPA1B	2.86e-04	169	34	3	d5624e5b3687bd3f18f3a2b47a94d11eb1fbdb75
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA1A ITGB7 HSPA8	2.86e-04	169	34	3	d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	2.91e-04	170	34	3	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 FAM20A ITGB7	2.96e-04	171	34	3	8719a18c9e6b6f5d8ec4e937c2bda1e36441c9ec
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 FAM20A ITGB7	2.96e-04	171	34	3	f4cdd7862c8fe99ee765a2f3ed375b584f4976c5
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPA1A ITGB7 HSPA8	3.17e-04	175	34	3	baaffc9af61f12168d6f7b96eb0b6e98a44a3909
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PTPN13 GSDME HSPA1A	3.22e-04	176	34	3	56c055488e34605d32562571a2fee621b47c9441
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 FAM20A HSPA1B	3.27e-04	177	34	3	4553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell	(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(1)_Control_(PBS) / Stress and Cell class	HSPA1A HSPA1B HSPA8	3.27e-04	177	34	3	d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIF27 FAM20A DHX34	3.27e-04	177	34	3	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	Dendritic_Cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CD1A FCGBP ITGB7	3.33e-04	178	34	3	3a28103cf282cc3637d1875a3b4cd7ddf3207687
ToppCell	BAL-Control-Myeloid-MoAM-MoAM2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM20A HSPA1A HSPA1B	3.38e-04	179	34	3	2fca4117c58824562ec80c7713fe15689a28efb3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.38e-04	179	34	3	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	BAL-Control-Myeloid-MoAM-MoAM2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM20A HSPA1A HSPA1B	3.38e-04	179	34	3	898425fa81526a2e00fca7a25085229ff1f31069
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPA1A ITGB7 HSPA8	3.38e-04	179	34	3	9af894dfbe44e9706f5d178769ceda3b4e2d89c0
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CD1A GSDME FCGBP	3.44e-04	180	34	3	289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCell	BAL-Control-Myeloid-MoAM-MoAM2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAM20A HSPA1A HSPA1B	3.44e-04	180	34	3	dcec59d66995f701d816eaeea3ed1439a2f71b73
ToppCell	BAL-Control-Myeloid-MoAM-MoAM2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM20A HSPA1A HSPA1B	3.44e-04	180	34	3	f3d8329b7e754c1ed89b0f39b8cd9e2ae22f6725
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KIF27 FAM20A DHX34	3.44e-04	180	34	3	a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCell	Control-Myeloid-MoAM2\|Control / Disease group,lineage and cell class （2021.01.30）	FAM20A HSPA1A HSPA1B	3.44e-04	180	34	3	38892483a6a5388765aec87f0119c0b9bb5c7cbd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A	3.44e-04	180	34	3	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD4 MED12L PTPN13	3.44e-04	180	34	3	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A	3.50e-04	181	34	3	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPA1A ITGB7 HSPA8	3.50e-04	181	34	3	e8c715fa3a0fed43ad4788b2d06cf45ab2c9e202
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|tumor_Lung / Location, Cell class and cell subclass	CD1A GSDME FCGBP	3.55e-04	182	34	3	243779ba1009097f8fafa1a691e296ec3aeefc04
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	CD1A FCGBP ITGB7	3.55e-04	182	34	3	8dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	THSD4 HSPA1A HSPA1B	3.55e-04	182	34	3	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.61e-04	183	34	3	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	3.61e-04	183	34	3	514b72a1ae55656934839800513385e19bc240e2
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.61e-04	183	34	3	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	3.67e-04	184	34	3	49eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B PTPN13 FCGBP	3.67e-04	184	34	3	41164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-B_cells-Naive_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1A HSPA1A HSPA8	3.67e-04	184	34	3	a068ae741889d59937690c11e0bf405481402c25
ToppCell	IPF-Myeloid-DC_Langerhans\|IPF / Disease state, Lineage and Cell class	MED12L CD1A FCGBP	3.73e-04	185	34	3	f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCell	IPF-Myeloid-DC_Langerhans\|Myeloid / Disease state, Lineage and Cell class	MED12L CD1A FCGBP	3.73e-04	185	34	3	ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.73e-04	185	34	3	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.73e-04	185	34	3	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 FAM20A ITGB7	3.73e-04	185	34	3	ea3ff0bd3f312bd2e93227ecf6ed577366aab3e0
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.73e-04	185	34	3	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	HSPA1A HSPA1B HSPA8	3.73e-04	185	34	3	b8cd94cf18308b514fc61557550225794ffd2860
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.73e-04	185	34	3	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCGBP FAM20A ITGB7	3.85e-04	187	34	3	59d28f4ee1d463ae20abb8d7e7399b504d80698a
ToppCell	Control-Myeloid-MoAM5\|Control / Disease group,lineage and cell class （2021.01.30）	FCGBP FAM20A ITGB7	3.85e-04	187	34	3	8769341be67382cea2a590d962f4def7c39de883
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCGBP FAM20A ITGB7	3.85e-04	187	34	3	25adf648c05c21534b4913254e73d43fc5f64e06
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FCGBP FAM20A ITGB7	3.85e-04	187	34	3	3b0cfa9e5ea5e7d6dda689c328b9b5110b43ee1d
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FCGBP FAM20A ITGB7	3.85e-04	187	34	3	0d589de12108230ced5b60229564f4a181e2f172
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.85e-04	187	34	3	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.91e-04	188	34	3	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	THSD4 HSPA1A HSPA1B	3.91e-04	188	34	3	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.91e-04	188	34	3	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17\|lymph-node_spleen / Manually curated celltypes from each tissue	PTPN13 HSPA1A HSPA8	3.91e-04	188	34	3	a20521198c6db17589535fb439533329582c9dd2
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 HSPA1A HSPA1B	3.91e-04	188	34	3	61f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A	3.91e-04	188	34	3	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	COVID-19-kidney-T-cells-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPA1A HSPA1B HSPA8	3.91e-04	188	34	3	15484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCell	droplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 HSPA1A HSPA1B	3.91e-04	188	34	3	7553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.97e-04	189	34	3	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 FAM20A ADAM22	3.97e-04	189	34	3	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	(02)_Cycling_Basal_(regeneration)-(1)_24hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	HSPA1A HSPA1B HSPA8	3.97e-04	189	34	3	311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCell	control-Myeloid-CD14_Monocytes_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PTPN13 FAM20A HSPA8	3.97e-04	189	34	3	7f78b5bb8195f99b18082cbb612e9199b7a1538c
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MUC5B FCGBP HSPA1B	3.97e-04	189	34	3	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MUC5B FCGBP HSPA1B	3.97e-04	189	34	3	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM132C PTPN13 FAM20A	3.97e-04	189	34	3	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 TMEM132C ADAM22	3.97e-04	189	34	3	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PTPN13 FAM20A	4.03e-04	190	34	3	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	ILEUM-non-inflamed\|ILEUM / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HSPA1A HSPA1B ITGB7	4.09e-04	191	34	3	c4a78ef7b87ffadbb1b9b69cbfa7c164ca456f9a
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSPA1A HSPA1B HSPA8	8.71e-05	50	19	3	GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSPA1A HSPA1B HSPA8	8.71e-05	50	19	3	GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
Drug	Azetidinecarboxylic Acid	HSPA1A HSPA1B	1.15e-05	4	32	2	ctd:D001383
Drug	2-phenylacetylenesulfonamide	HSPA1A HSPA1B	1.91e-05	5	32	2	ctd:C545747
Drug	polaprezinc	HSPA1A HSPA1B	2.86e-05	6	32	2	ctd:C061957
Drug	geranylgeranylacetone	HSPA1A HSPA1B	2.86e-05	6	32	2	ctd:C031049
Drug	formetanate	HSPA1A HSPA8	2.86e-05	6	32	2	ctd:C100163
Drug	benz(a)anthracene	THSD4 HSPA1A DHX34 HSPA8 ADAM22 AKAP7 ARIH2 ZNF641 REV1	3.94e-05	1251	32	9	ctd:C030935
Drug	LL Z1640-2	MAPK9 HSPA1B	4.00e-05	7	32	2	ctd:C118715
Drug	pirimicarb	HSPA1A HSPA8	4.00e-05	7	32	2	ctd:C011994
Drug	triphenyl(phenylethynyl)phosphonium	HSPA1A HSPA1B	5.33e-05	8	32	2	ctd:C000608764
Disease	graft-versus-host disease (biomarker_via_orthology)	HSPA1A HSPA1B HSPA8	1.05e-08	5	31	3	DOID:0081267 (biomarker_via_orthology)
Disease	Major depression, single episode	HSPA1A HSPA1B	3.83e-05	9	31	2	C0024517
Disease	Reperfusion Injury	MAPK9 HSPA1A HSPA8	1.12e-04	89	31	3	C0035126
Disease	Carcinoma, Pancreatic Ductal	HSPA1A HSPA1B	2.91e-04	24	31	2	C0887833
Disease	complement C4b measurement	HSPA1A HSPA1B	3.16e-04	25	31	2	EFO_0008092
Disease	Arsenic Induced Polyneuropathy	TRAPPC10 HSPA1B	1.94e-03	62	31	2	C0751852
Disease	Arsenic Encephalopathy	TRAPPC10 HSPA1B	1.94e-03	62	31	2	C0751851
Disease	Arsenic Poisoning	TRAPPC10 HSPA1B	1.94e-03	62	31	2	C0311375
Disease	Arsenic Poisoning, Inorganic	TRAPPC10 HSPA1B	1.94e-03	62	31	2	C0274861
Disease	Nervous System, Organic Arsenic Poisoning	TRAPPC10 HSPA1B	1.94e-03	62	31	2	C0274862
Disease	serum dimethylarginine measurement	THSD4 PTPN13	2.00e-03	63	31	2	EFO_0005418
Disease	Dermatologic disorders	TRAPPC10 HSPA1B	2.83e-03	75	31	2	C0037274
Disease	urinary bladder cancer (is_implicated_in)	MUC5B HSPA1A	2.90e-03	76	31	2	DOID:11054 (is_implicated_in)
Disease	schizophrenia (is_implicated_in)	HSPA1A HSPA1B	3.05e-03	78	31	2	DOID:5419 (is_implicated_in)
Disease	psoriatic arthritis	HSPA1A HSPA1B	3.78e-03	87	31	2	EFO_0003778
Disease	R-6-hydroxywarfarin to R-warfarin ratio measurement	THSD4 TMEM132C	5.55e-03	106	31	2	EFO_0803333
Disease	Drug Use Disorders	THSD4 AKAP7	6.50e-03	115	31	2	C0013222
Disease	Drug Dependence	THSD4 AKAP7	6.50e-03	115	31	2	C1510472
Disease	Drug habituation	THSD4 AKAP7	6.50e-03	115	31	2	C0013170

Protein segments in the cluster

Peptide	Gene	Start	Entry
HCESSIVIGEKNGGE	AKAP7	276	Q9P0M2
SEHMQVEEKCGGIVG	GSDME	171	O60443
EHGGKTVEVKGGEHC	ADAM22	121	Q9P0K1
GQVCTGVHVGAKEQE	CD300LD-AS1	141	Q96MU5
EQHCSVLVKDGVGVG	ARIH2	166	O95376
VVHDEGAVCSCTGGK	MUC5B	766	Q9HC84
GELVKGCVIFQGTDH	MAPK9	216	P45984
TAQVFEGLCGVVKHV	MED12L	901	Q86YW9
FEIQVTGGCELHSGK	CD1A	111	P06126
SCVGVFQHGKVEIIA	HSPA1B	16	P0DMV9
GGHIASVVEGQKGII	KIF27	96	Q86VH2
NGCEEGKSQETLHGV	MINDY4B	316	A8MYZ0
EGQSGVTIKHVACGD	NEK8	386	Q86SG6
ADHTQAIVLGCVGGI	ITGB7	721	P26010
VAVIVSNDHAGKLCG	FCGBP	5356	Q9Y6R7
HIEKIIGSGDSGEVC	EPHA8	636	P29322
SCVGVFQHGKVEIIA	HSPA1A	16	P0DMV8
KEHQVVVVAGDTGCG	DHX34	176	Q14147
GVCSKGVLVFEVHNG	PTPN13	796	Q12923
SCVGVFQHGKVEIIA	HSPA8	16	P11142
VGSGGKHVTATVACQ	TMEM132C	351	Q8N3T6
GCIVAHGQQSVIVDG	FAM20A	511	Q96MK3
KPGDVAVHGEAVVCV	POLR3A	1161	O14802
VETAKFGGHGICDNI	REV1	766	Q9UBZ9
HGVNDKVTVIGAGVT	TKTL2	501	Q9H0I9
GEHMGVCSEDGKVQV	VPS41	96	P49754
HRVGTVAEAVACIQG	PRSS48	301	Q7RTY5
FVDEHTVCGVAKGGK	TXNRD2	161	Q9NNW7
AIVGEIGHGCNEGEK	ZNF594	76	Q96JF6
SNAVVHVGGVLCVEI	TRAPPC10	596	P48553
GDNTGCQVVSGVFKH	THSD4	406	Q6ZMP0
QKDGDGCTVLHVVAA	TRANK1	236	O15050
SVGECEVHKGGYNEV	ZNF722	131	A0A1W2PQL4
VHAEGKSCKGQEVGE	ZNF641	341	Q96N77