Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 NSD1 ISL2 ISL1 ZNF354B ZNF263 ZNF610 AGO1 ZNF792 GLI1 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287 VDR	4.79e-07	1271	146	27	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 NSD1 ISL1 ZNF354B ZNF263 ZNF610 AGO1 ZNF792 GLI1 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287 VDR	1.10e-06	1244	146	26	GO:0000978
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	DCAF1 ZNF366 NSD1 ISL1 CNOT1 DNMT1	2.38e-06	53	146	6	GO:0030331
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 NSD1 ISL1 ZNF354B ZNF77 ZNF263 ZNF610 AGO1 ZNF792 GLI1 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287 VDR	6.56e-06	1459	146	27	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ABHD2 ISL2 ISL1 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 GLI1 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287 VDR	3.20e-05	1412	146	25	GO:0000981
GeneOntologyMolecularFunction	nuclear receptor binding	DCAF1 ZNF366 NSD1 ISL1 DDX5 CNOT1 DNMT1 VDR	7.14e-05	187	146	8	GO:0016922
Domain	zf-C2H2	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	1.90e-11	693	144	26	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287	3.98e-11	775	144	27	PS50157
Domain	KRAB	ZNF586 ZNF211 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	3.99e-11	358	144	19	PS50805
Domain	KRAB	ZNF586 ZNF211 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	3.99e-11	358	144	19	PF01352
Domain	ZINC_FINGER_C2H2_1	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287	4.22e-11	777	144	27	PS00028
Domain	KRAB	ZNF586 ZNF211 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	6.70e-11	369	144	19	SM00349
Domain	KRAB	ZNF586 ZNF211 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF483 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	7.02e-11	370	144	19	IPR001909
Domain	Znf_C2H2-like	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287	7.27e-11	796	144	27	IPR015880
Domain	ZnF_C2H2	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287	1.02e-10	808	144	27	SM00355
Domain	Znf_C2H2/integrase_DNA-bd	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	1.16e-10	694	144	25	IPR013087
Domain	-	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681	4.18e-10	679	144	24	3.30.160.60
Domain	Znf_C2H2	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30 ZNF681 ZNF287	4.93e-10	805	144	26	IPR007087
Domain	zf-C2H2_6	ZNF384 ZNF586 ZNF211 ZNF366 ZNF354B ZNF77 ZNF792 ZNF483 ZNF480 ZNF616 ZNF766 ZNF420 ZNF30 ZNF681	1.49e-07	314	144	14	PF13912
Domain	Clathrin_H-chain_propeller_rpt	CLTCL1 CLTC	5.90e-05	2	144	2	IPR022365
Domain	Clathrin-link	CLTCL1 CLTC	5.90e-05	2	144	2	PF09268
Domain	-	CLTCL1 CLTC	5.90e-05	2	144	2	2.130.10.110
Domain	Clathrin_heavy_chain	CLTCL1 CLTC	5.90e-05	2	144	2	IPR016341
Domain	MeTrfase_trithorax	KMT2B KMT2A	5.90e-05	2	144	2	IPR016569
Domain	Clathrin_H-chain_propeller_N	CLTCL1 CLTC	5.90e-05	2	144	2	IPR001473
Domain	DUF5050	LRP1B LRP1	5.90e-05	2	144	2	IPR032485
Domain	Clathrin_H-chain_link/propller	CLTCL1 CLTC	5.90e-05	2	144	2	IPR016025
Domain	Clathrin_propel	CLTCL1 CLTC	5.90e-05	2	144	2	PF01394
Domain	Clathrin_H-chain_linker_core	CLTCL1 CLTC	5.90e-05	2	144	2	IPR015348
Domain	DUF5050	LRP1B LRP1	5.90e-05	2	144	2	PF16472
Domain	ZF_CXXC	KMT2B KMT2A DNMT1	7.08e-05	11	144	3	PS51058
Domain	Znf_CXXC	KMT2B KMT2A DNMT1	7.08e-05	11	144	3	IPR002857
Domain	zf-CXXC	KMT2B KMT2A DNMT1	7.08e-05	11	144	3	PF02008
Domain	Clathrin_H-chain_linker	CLTCL1 CLTC	1.76e-04	3	144	2	IPR012331
Domain	CLH	CLTCL1 CLTC	1.76e-04	3	144	2	SM00299
Domain	Post-SET_dom	KMT2B NSD1 KMT2A	2.34e-04	16	144	3	IPR003616
Domain	PostSET	KMT2B NSD1 KMT2A	2.34e-04	16	144	3	SM00508
Domain	POST_SET	KMT2B NSD1 KMT2A	2.34e-04	16	144	3	PS50868
Domain	SET	KMT2B NSD1 PRDM12 KMT2A	4.30e-04	46	144	4	SM00317
Domain	FYrich_C	KMT2B KMT2A	5.81e-04	5	144	2	IPR003889
Domain	FYrich_N	KMT2B KMT2A	5.81e-04	5	144	2	IPR003888
Domain	FYRC	KMT2B KMT2A	5.81e-04	5	144	2	SM00542
Domain	FYRN	KMT2B KMT2A	5.81e-04	5	144	2	SM00541
Domain	BAAT_C	ACOT1 ACOT6	5.81e-04	5	144	2	IPR014940
Domain	ICAM_N	ICAM3 ICAM4	5.81e-04	5	144	2	PF03921
Domain	ICAM_N	ICAM3 ICAM4	5.81e-04	5	144	2	IPR013768
Domain	FYRN	KMT2B KMT2A	5.81e-04	5	144	2	PF05964
Domain	FYRC	KMT2B KMT2A	5.81e-04	5	144	2	PF05965
Domain	FYRC	KMT2B KMT2A	5.81e-04	5	144	2	PS51543
Domain	FYRN	KMT2B KMT2A	5.81e-04	5	144	2	PS51542
Domain	BAAT_C	ACOT1 ACOT6	5.81e-04	5	144	2	PF08840
Domain	SET_dom	KMT2B NSD1 PRDM12 KMT2A	5.93e-04	50	144	4	IPR001214
Domain	SET	KMT2B NSD1 PRDM12 KMT2A	5.93e-04	50	144	4	PS50280
Domain	-	RNF32 TRAF5 RNF168 KMT2B NSD1 BARD1 UBOX5 PHF3 KMT2A FGD6 RNF208	7.30e-04	449	144	11	3.30.40.10
Domain	ICAM_VCAM_N	ICAM3 ICAM4	8.68e-04	6	144	2	IPR003987
Domain	Znf_RING/FYVE/PHD	RNF32 TRAF5 RNF168 KMT2B NSD1 BARD1 UBOX5 PHF3 KMT2A FGD6 RNF208	8.74e-04	459	144	11	IPR013083
Domain	-	ETFDH CFAP61 MTO1 SMOX	9.12e-04	56	144	4	3.50.50.60
Domain	FAD/NAD-binding_dom	ETFDH CFAP61 MTO1 SMOX	9.75e-04	57	144	4	IPR023753
Domain	cEGF	MATN2 LRP1B LRP1	1.02e-03	26	144	3	PF12662
Domain	cEGF	MATN2 LRP1B LRP1	1.02e-03	26	144	3	IPR026823
Domain	Clathrin	CLTCL1 CLTC	1.21e-03	7	144	2	PF00637
Domain	CHCR	CLTCL1 CLTC	1.21e-03	7	144	2	PS50236
Domain	Clathrin_H-chain/VPS_repeat	CLTCL1 CLTC	1.60e-03	8	144	2	IPR000547
Domain	zf-C2H2_11	ZNF354B ZNF592	2.05e-03	9	144	2	PF16622
Domain	-	ABHD2 ACOT1 ACOT6 SPG21 LIPC	2.30e-03	119	144	5	3.40.50.1820
Domain	AB_hydrolase	ABHD2 ACOT1 ACOT6 SPG21 LIPC	2.30e-03	119	144	5	IPR029058
Domain	PHD	KMT2B NSD1 PHF3 KMT2A	2.70e-03	75	144	4	PF00628
Domain	Znf_PHD-finger	KMT2B NSD1 PHF3 KMT2A	3.25e-03	79	144	4	IPR019787
Domain	Quinoprot_gluc/sorb_DH	EML5 LRP1	3.70e-03	12	144	2	IPR011041
Domain	SET	KMT2B NSD1 KMT2A	3.86e-03	41	144	3	PF00856
Domain	PHD	KMT2B NSD1 PHF3 KMT2A	4.99e-03	89	144	4	SM00249
Domain	Ldl_recept_b	LRP1B LRP1	5.06e-03	14	144	2	PF00058
Domain	LDLRB	LRP1B LRP1	5.06e-03	14	144	2	PS51120
Domain	Znf_PHD	KMT2B NSD1 PHF3 KMT2A	5.39e-03	91	144	4	IPR001965
Domain	Znf_FYVE_PHD	KMT2B NSD1 PHF3 KMT2A FGD6	5.66e-03	147	144	5	IPR011011
Domain	LY	LRP1B LRP1	5.80e-03	15	144	2	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP1	5.80e-03	15	144	2	IPR000033
Domain	ZF_PHD_2	KMT2B NSD1 PHF3 KMT2A	6.27e-03	95	144	4	PS50016
Domain	ZF_PHD_1	KMT2B NSD1 PHF3 KMT2A	6.51e-03	96	144	4	PS01359
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DCAF1 WDR7 MARK3 IGDCC4 FOCAD KLHL29 PHF3 CLTC NAV3 SUZ12 KIF17 ARHGAP21 SENP7	2.34e-08	407	148	13	12693553
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF263 ZNF610 ZNF616 ZNF420 ZNF681 ZNF287	6.45e-08	49	148	6	9630514
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF384 RNF168 KMT2B NSD1 BARD1 DMAP1 ZNF592 PHF3 ZNF483 KMT2A SUZ12 SENP7 DNMT1 HELLS	3.69e-07	608	148	14	36089195
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DLGAP1 DCHS2 SPTBN1 ACOT1 ARMCX4 LRP1B TF DMAP1 TMEFF1 FOCAD JAK1 DGLUCY CS ADAMTS9 ZNF592 CLTC NAV3 LRP1 ARHGAP21 DNMT1	5.92e-07	1285	148	20	35914814
Pubmed	Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.	ISL2 ISL1 GLI1 GREM1	1.45e-06	20	148	4	28379358
Pubmed	Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases.	ICAM3 ICAM4 ITGB2	1.50e-06	6	148	3	11857637
Pubmed	Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.	DAPK1 ACE TF	1.50e-06	6	148	3	18813964
Pubmed	MuSK controls where motor axons grow and form synapses.	ISL2 ISL1 MUSK	2.61e-06	7	148	3	18084289
Pubmed	LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth.	ISL2 ISL1 GLI1 GREM1	3.72e-06	25	148	4	19304889
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZBTB6 RHBDF1 ABHD2 SPTBN1 SUN1 TTC14 NSD1 UBOX5 TMEFF1 EML5 GLI1 CLTC PEAK1 PAN3 MTO1 CNOT1 ARHGAP21	4.01e-06	1084	148	17	11544199
Pubmed	Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.	ISL2 ISL1 GLI1	6.23e-06	9	148	3	10725236
Pubmed	Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction.	ISL2 ISL1 MUSK	6.23e-06	9	148	3	18830404
Pubmed	Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.	ISL2 ISL1 GLI1	6.23e-06	9	148	3	12361967
Pubmed	Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.	DCAF1 CLTCL1 DDX5 CLTC	7.92e-06	30	148	4	22963397
Pubmed	Candidate gene polymorphisms for ischemic stroke.	ICAM4 ACE LIPC NOS3 VDR	8.12e-06	64	148	5	19729601
Pubmed	Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.	ISL2 ISL1 GLI1	8.87e-06	10	148	3	12812795
Pubmed	Gli1 can rescue the in vivo function of Gli2.	ISL2 ISL1 GLI1	8.87e-06	10	148	3	11748151
Pubmed	Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation.	ISL2 ISL1 MUSK	8.87e-06	10	148	3	11395002
Pubmed	Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis.	ACE LIPC NOS3	8.87e-06	10	148	3	16928730
Pubmed	ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.	KMT2A SUZ12 DNMT1	8.87e-06	10	148	3	20569692
Pubmed	An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles.	ISL2 ISL1 MUSK	1.22e-05	11	148	3	11988168
Pubmed	The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.	ISL2 ISL1 SEMA5B GLI1	1.32e-05	34	148	4	25631876
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF211 ZNF354B ZNF77 ZNF792 ZNF480 ZNF766 ZNF681	1.33e-05	181	148	7	37372979
Pubmed	AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis.	ISL2 ISL1 GLI1	1.62e-05	12	148	3	20150232
Pubmed	Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.	ISL1 GLI1 GREM1	1.62e-05	12	148	3	28530676
Pubmed	Association between genetic polymorphisms of ACE & eNOS and diabetic nephropathy.	ACE NOS3	1.80e-05	2	148	2	25227524
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.80e-05	2	148	2	15963947
Pubmed	[GENES ALLELE STATUS OF ANGIOTENSINCONVERTING ENZYME (I/D) AND ENDOTHELIAL NITRIC OXIDE SYNTHASE (894 G > T) IN PATIENTS WITH ACUTE CORONARY SYNDROME].	ACE NOS3	1.80e-05	2	148	2	27089712
Pubmed	Association between Endothelial nitric oxide synthase and Hepatic lipase gene polymorphisms with the risk of coronary artery disease in Southern Iran population - A case control study.	LIPC NOS3	1.80e-05	2	148	2	33673789
Pubmed	ACE I allele and eNOS G allele crosstalk may have a role in chronic obstructive pulmonary disease.	ACE NOS3	1.80e-05	2	148	2	15498534
Pubmed	Effects of human endothelial gene polymorphisms on cellular responses to hyperglycaemia: role of NOS3 (Glu298Asp) and ACE (I/D) polymorphisms.	ACE NOS3	1.80e-05	2	148	2	21844127
Pubmed	Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme.	GLI1 NOS3	1.80e-05	2	148	2	11821712
Pubmed	[The influence of single nucleotide polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme on the course of pregnancy complicated by type 1 diabetes].	ACE NOS3	1.80e-05	2	148	2	24505959
Pubmed	Association of Polymorphisms in Endothelial Nitric Oxide Synthesis and Renin-Angiotensin-Aldosterone System with Developing of Coronary Artery Disease in Bulgarian Patients.	ACE NOS3	1.80e-05	2	148	2	26670794
Pubmed	eNOS gene Glu298Asp variant confer risk in sudden sensorineural hearing loss.	NOS3 VDR	1.80e-05	2	148	2	30354859
Pubmed	Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation.	ACE NOS3	1.80e-05	2	148	2	12687832
Pubmed	[Relations between endothelial nitric oxide synthase and angiotensin-converting gene polymorphisms and certain biochemical parameters in patients with cardiac syndrome X].	ACE NOS3	1.80e-05	2	148	2	15724677
Pubmed	The cellular internalization and degradation of hepatic lipase is mediated by low density lipoprotein receptor-related protein and requires cell surface proteoglycans.	LIPC LRP1	1.80e-05	2	148	2	7721852
Pubmed	Genetic susceptibility to atrial fibrillation in patients with congestive heart failure.	ACE NOS3	1.80e-05	2	148	2	16818212
Pubmed	Genetic predisposition to breath-hold diving-induced hemoptysis: Preliminary study.	ACE NOS3	1.80e-05	2	148	2	26094307
Pubmed	[Association between angiotensin-converting enzyme and endothelial nitric oxide synthase gene polymorphism and risk of coronary artery disease].	ACE NOS3	1.80e-05	2	148	2	18269824
Pubmed	Association of angiotensin-converting enzyme and endothelial Nitric Oxide synthase gene polymorphisms with vascular disease in ESRD patients in a Chinese population.	ACE NOS3	1.80e-05	2	148	2	18629615
Pubmed	Correlation between common genetic variants and risk factors associated with prediction of cardiovascular diseases in dyslipidemic patients.	ACE NOS3	1.80e-05	2	148	2	21919778
Pubmed	Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with lung cancer.	ACE NOS3	1.80e-05	2	148	2	11361058
Pubmed	Association between the NOS3 (-786 T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease.	ACE NOS3	1.80e-05	2	148	2	11485372
Pubmed	High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide synthase (Glu298Asp) in patients with systemic sclerosis.	ACE NOS3	1.80e-05	2	148	2	12015245
Pubmed	eNOS and ACE genes influence peripheral arterial disease predisposition in smokers.	ACE NOS3	1.80e-05	2	148	2	20478683
Pubmed	ACE I/D and eNOS E298D gene polymorphisms in Saudi subjects with hypertension.	ACE NOS3	1.80e-05	2	148	2	23042814
Pubmed	Association of the genetic polymorphisms of the ACE gene and the eNOS gene with lupus nephropathy in northern Chinese population.	ACE NOS3	1.80e-05	2	148	2	20540812
Pubmed	Angiotensin-converting enzyme and endothelial constitutive nitric oxide synthase polymorphisms in Turkish renal transplant population and possible influence on renal artery atherosclerosis and graft survival.	ACE NOS3	1.80e-05	2	148	2	16213264
Pubmed	Relations between ACE gene and ecNOS gene polymorphisms and resistive index in type 2 diabetic patients with nephropathy.	ACE NOS3	1.80e-05	2	148	2	11522715
Pubmed	Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease.	ACE NOS3	1.80e-05	2	148	2	14989558
Pubmed	Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.	ICAM3 ITGB2	1.80e-05	2	148	2	7822326
Pubmed	Endothelial dysfunction in patients with asthma: the role of polymorphisms of ACE and endothelial NOS genes.	ACE NOS3	1.80e-05	2	148	2	15115168
Pubmed	Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses.	NOS3 DNMT1	1.80e-05	2	148	2	23867713
Pubmed	Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with asthma.	ACE NOS3	1.80e-05	2	148	2	11030378
Pubmed	Association of eNOS and ACE gene polymorphisms and plasma nitric oxide with risk of non-small cell lung cancer in South India.	ACE NOS3	1.80e-05	2	148	2	27328622
Pubmed	Lack of association between endothelial nitric oxide synthase gene polymorphisms, microalbuminuria and endothelial dysfunction in hypertensive men.	ACE NOS3	1.80e-05	2	148	2	17563560
Pubmed	Association of eNOS and ACE Polymorphisms with Retinopathy of Prematurity: A Systematic Review and Meta-Analysis.	ACE NOS3	1.80e-05	2	148	2	31437068
Pubmed	Lack of association of NOS3 and ACE gene polymorphisms with coronary artery disease in Southern Tunisia.	ACE NOS3	1.80e-05	2	148	2	23011259
Pubmed	ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction.	ACE NOS3	1.80e-05	2	148	2	12837457
Pubmed	Aspects of the molecular-genetic profile in patients with ischemic heart disease.	ACE NOS3	1.80e-05	2	148	2	24505896
Pubmed	Distinct roles of DMAP1 in mouse development.	DMAP1 DNMT1	1.80e-05	2	148	2	21383065
Pubmed	Polymorphisms of angiotensin converting enzyme and nitric oxide synthase 3 genes as risk factors of high-altitude pulmonary edema: a case-control study and meta-analysis.	ACE NOS3	1.80e-05	2	148	2	23603420
Pubmed	Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.	CLTCL1 CLTC	1.80e-05	2	148	2	8733129
Pubmed	KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.	KMT2B KMT2A	1.80e-05	2	148	2	28723559
Pubmed	Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD).	ACE NOS3	1.80e-05	2	148	2	22695028
Pubmed	Association study of ACE and eNOS single nucleotide polymorphisms with Henoch-Schönlein purpura nephritis.	ACE NOS3	1.80e-05	2	148	2	22895845
Pubmed	Angiotensin-converting enzyme/vitamin D receptor gene polymorphisms and bioelectrical impedance analysis in predicting athletic performances of Italian young soccer players.	ACE VDR	1.80e-05	2	148	2	21747292
Pubmed	LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.	ITGB2 LRP1	1.80e-05	2	148	2	15328156
Pubmed	Angiotensin-converting enzyme gene and endothelial nitric oxide synthase gene polymorphisms in Behçet's disease with or without ocular involvement.	ACE NOS3	1.80e-05	2	148	2	19255721
Pubmed	CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.	CLTCL1 CLTC	1.80e-05	2	148	2	29097553
Pubmed	Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic efficacy of salvianolate injection in Chinese patients with coronary heart disease.	ACE NOS3	1.80e-05	2	148	2	24827774
Pubmed	Glu298Asp endothelial nitric oxide synthase polymorphism is a risk factor for erectile dysfunction in the Mexican Mestizo population.	ACE NOS3	1.80e-05	2	148	2	15292102
Pubmed	The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.	CLTCL1 CLTC	1.80e-05	2	148	2	20065094
Pubmed	Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow.	ACE NOS3	1.80e-05	2	148	2	16915032
Pubmed	Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.	ACE NOS3	1.80e-05	2	148	2	15338496
Pubmed	Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice.	NOS3 VDR	1.80e-05	2	148	2	24284821
Pubmed	Tgfbr1 controls developmental plasticity between the hindlimb and external genitalia by remodeling their regulatory landscape.	ISL1 GLI1 GREM1	2.09e-05	13	148	3	38509075
Pubmed	Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.	ISL2 ISL1 GLI1	2.09e-05	13	148	3	9636069
Pubmed	A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).	ACE ITGB2 LIPC LRP1 NOS3	2.42e-05	80	148	5	19420105
Pubmed	A hypomorphic allele reveals an important role of inturned in mouse skeletal development.	ISL2 ISL1 GLI1	2.66e-05	14	148	3	25774014
Pubmed	Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures.	ISL2 ISL1 GLI1	2.66e-05	14	148	3	21674568
Pubmed	Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice.	ISL2 ISL1 CLTC	2.66e-05	14	148	3	29962937
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PUS3 COPG1 WDR7 ARFGEF1 PKHD1L1 BTBD3 PI4KB CLTC ADAMTS16 PEAK1 ARHGAP21 DNMT1 HELLS	3.01e-05	777	148	13	35844135
Pubmed	Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.	ACE LRP1 NOS3	3.31e-05	15	148	3	11436125
Pubmed	Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.	ACE LIPC NOS3 VDR	3.41e-05	43	148	4	20565774
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PARP14 DMAP1 ZNF592 PRDM12 KMT2A SUZ12 CNOT1 DNMT1 VDR HELLS	3.51e-05	469	148	10	27634302
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KMT2B KMT2A SUZ12 DNMT1	3.74e-05	44	148	4	24183668
Pubmed	Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.	ISL2 ISL1 GLI1	4.06e-05	16	148	3	28800946
Pubmed	Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain.	ISL2 ISL1 GLI1	4.06e-05	16	148	3	17026983
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	CLTCL1 COPG1 SPTBN1 DAPK1 ACE DDX5 CS PPA2 CLTC KMT2A PEAK1 MYO15A CNOT1	4.43e-05	807	148	13	30575818
Pubmed	Genome-wide association analysis of age-at-onset in Alzheimer's disease.	DCHS2 ADAMTS9 ZNF592	4.91e-05	17	148	3	22005931
Pubmed	Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.	DAPK1 ACE TF	4.91e-05	17	148	3	20413850
Pubmed	Lp(a) and risk of recurrent cardiac events in obese postinfarction patients.	ACE LIPC NOS3	4.91e-05	17	148	3	18927546
Pubmed	Differential Islet-1 expression among lumbosacral spinal motor neurons in prenatal mouse.	ISL2 ISL1	5.38e-05	3	148	2	19236857
Pubmed	Concentrations of eNOS, VEGF, ACE and PlGF in maternal blood as predictors of impaired fetal growth in pregnancy complicated by gestational hypertension/preeclampsia.	ACE NOS3	5.38e-05	3	148	2	25181428
Pubmed	Endothelial constitutive nitric oxide synthase, angiotensin converting enzyme, angiotensin II type 1 receptor gene polymorphisms and endothelial functions in healthy individuals.	ACE NOS3	5.38e-05	3	148	2	24452940
Pubmed	Endothelial function and germ-line ACE I/D, eNOS and PAI-1 gene profiles in patients with coronary slow flow in the Canakkale population: multiple thrombophilic gene profiles in coronary slow flow.	ACE NOS3	5.38e-05	3	148	2	24435163
Pubmed	Associations of uric acid with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.	NOS3 VDR	5.38e-05	3	148	2	16263504
Interaction	LCOR interactions	ACOT1 POLR1G LRP1B TF DGLUCY CS NAV3 LRP1 SUZ12 DNMT1 VDR	1.47e-06	242	145	11	int:LCOR
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF134 ZNF586 ZNF211 KMT2B PSG11 ZNF233 ZNF230 POLR1G ZNF610 ZNF792 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 ZNF30	3.45e-07	1192	148	17	chr19q13
Cytoband	19q13.41	ZNF610 ZNF534 ZNF480 ZNF616 ZNF766	5.68e-06	78	148	5	19q13.41
Cytoband	3q21.1	PARP14 SEC22A SEMA5B	3.59e-05	20	148	3	3q21.1
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF384 ZNF134 ZBTB6 ZNF586 ZNF211 ZNF366 ZNF233 ZNF230 ZNF354B ZNF77 ZNF263 ZNF610 ZNF792 ZNF592 GLI1 ZNF483 PRDM12 ZNF534 ZNF480 ZNF616 ZNF766 ZNF420 ZNF470 SUZ12 ZNF30 ZNF681 ZNF287	1.18e-14	718	109	27	28
GeneFamily	Zinc fingers CXXC-type	KMT2B KMT2A DNMT1	4.51e-05	12	109	3	136
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B NSD1 KMT2A	1.11e-03	34	109	3	487
GeneFamily	Acyl-CoA thioesterases	ACOT1 ACOT6	1.57e-03	10	109	2	41
GeneFamily	PHD finger proteins	KMT2B NSD1 PHF3 KMT2A	2.15e-03	90	109	4	88
GeneFamily	LIM class homeoboxes	ISL2 ISL1	2.28e-03	12	109	2	522
GeneFamily	Low density lipoprotein receptors	LRP1B LRP1	2.69e-03	13	109	2	634
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	DAPK1 ACE RIMBP3 LRP1 FITM2 FGD6 ARHGAP21	1.94e-06	174	148	7	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCHS2 DGKG ISL2 ARMCX4 ZNF483 NAV3 GREM1	2.09e-06	176	148	7	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 UBOX5 DMAP1 IGDCC4 GLI1 ZNF616 ZNF470	2.91e-06	185	148	7	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 UBOX5 DMAP1 IGDCC4 GLI1 ZNF616 ZNF470	2.91e-06	185	148	7	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 ISL2 CXCL14 ISL1 VSTM4 GLI1 LRP1	3.72e-06	192	148	7	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 ISL2 CXCL14 ISL1 VSTM4 GLI1 LRP1	3.72e-06	192	148	7	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 ISL2 CXCL14 ISL1 VSTM4 GLI1 LRP1	3.72e-06	192	148	7	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF SEMA5B NAV3 PEAK1 NOS3	3.98e-06	194	148	7	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF SEMA5B NAV3 PEAK1 NOS3	4.55e-06	198	148	7	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	TRAF5 ZNF211 TBC1D2 TTC14 ZNF263 SEMA5B MYO15A	4.86e-06	200	148	7	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ISL1 RIMBP3 IL1RAPL2 PRDM12 GREM1 VDR	1.03e-05	148	148	6	afebb64365c94b9476494bffe7c364677f19c8cf
ToppCell	Thalamus-Neuronal-Inhibitory\|Thalamus / BrainAtlas - Mouse McCarroll V32	ISL1 RIMBP3 IL1RAPL2 PRDM12 GREM1 VDR	1.03e-05	148	148	6	5f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCell	343B-Fibroblasts-Fibroblast-D-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MATN2 ZNF77 GLI1 ADAMTS16 ZNF470 PALLD	1.78e-05	163	148	6	8d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCell	343B-Fibroblasts-Fibroblast-D\|343B / Donor, Lineage, Cell class and subclass (all cells)	MATN2 ZNF77 GLI1 ADAMTS16 ZNF470 PALLD	1.78e-05	163	148	6	acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCAF1 PUS3 CXCL14 SLC12A3 ZNF792 VDR	1.90e-05	165	148	6	50f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCell	facs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISL1 ARMCX4 PKHD1L1 BTBD3 ELMOD1 NOS3	2.04e-05	167	148	6	a4a795751644b22af616335379e64ae95175180c
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 TTC14 ISL1 DDX5 EML5 SEMA5B	2.04e-05	167	148	6	b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 COL27A1 LRP1B VSTM4 LRP1 PALLD	2.25e-05	170	148	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	TSPAN11 DYSF PKHD1L1 SEMA5B KIF17 NOS3	2.41e-05	172	148	6	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 DGKG DYSF PKHD1L1 KIF17 NOS3	2.41e-05	172	148	6	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAPK1 ITGB2 P4HA1 ANO7 TDRD6 KIF17	2.57e-05	174	148	6	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 COL27A1 IGDCC4 VSTM4 NAV3 LRP1	3.11e-05	180	148	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 KLHL29 LIPC ADAMTS9 ADAMTS16 ELMOD1	3.30e-05	182	148	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 DYSF SEMA5B NAV3 NOS3 HELLS	3.51e-05	184	148	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	(7)_DC_activated\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ZNF366 CXCL14 SLC12A3 FGD6 PALLD ARHGAP21	3.51e-05	184	148	6	b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	COL27A1 DAPK1 TF LIPC TBCK LRP1	3.62e-05	185	148	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 DMAP1 IGDCC4 GLI1 ZNF616 ZNF470	3.73e-05	186	148	6	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN11 MATN2 IGDCC4 VSTM4 GLI1 LRP1	3.73e-05	186	148	6	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 DMAP1 IGDCC4 GLI1 ZNF616 ZNF470	3.73e-05	186	148	6	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ZNF366 SPTBN1 PKHD1L1 INO80D ADAMTS9 NOS3	3.84e-05	187	148	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF NAV3 NOS3 HELLS	3.84e-05	187	148	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF366 SPTBN1 DYSF ADAMTS9 KIF17 NOS3	3.96e-05	188	148	6	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 MATN2 COL27A1 ACOT6 KLHL29 DNAI2	3.96e-05	188	148	6	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 DGKG DYSF PKHD1L1 FZD8 SEMA5B	4.20e-05	190	148	6	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Control-B_naive-4\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	POLR1G LRP1B FZD8 VSTM4 EML5	4.30e-05	116	148	5	35d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TRAF5 DGLUCY ZNF470 SUZ12 CNOT1 HELLS	4.32e-05	191	148	6	d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	WDR7 SUN1 NSD1 PARP14 TBCK HELLS	4.32e-05	191	148	6	9454f642c3621370fa23640b631301346b300950
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	PUS3 DMAP1 FOCAD ZNF420 GREM1 UBE2Z	4.45e-05	192	148	6	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	TSPAN11 SPTBN1 DYSF PKHD1L1 ADAMTS9 NOS3	4.58e-05	193	148	6	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 MATN2 ISL1 DDX5 EML5 CLTC	4.58e-05	193	148	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 MATN2 ISL1 DDX5 EML5 CLTC	4.58e-05	193	148	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 DGKG DYSF PKHD1L1 SEMA5B NOS3	4.72e-05	194	148	6	cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPAN11 MATN2 COL27A1 DAZL TF SMOX	4.72e-05	194	148	6	f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 MATN2 ISL1 DDX5 EML5 CLTC	4.72e-05	194	148	6	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 MATN2 ISL1 DDX5 EML5 CLTC	4.72e-05	194	148	6	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPAN11 MATN2 COL27A1 TF GREM1 SMOX	4.85e-05	195	148	6	1be9502577267ca2a04656a99d57e3e2f124d92e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 ARFGEF1 DDX5 CLTC KMT2A VDR	4.85e-05	195	148	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 DYSF SEMA5B NAV3 PEAK1 NOS3	4.99e-05	196	148	6	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF NAV3 PEAK1 NOS3	5.14e-05	197	148	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MATN2 GLI1 NAV3 GREM1 PALLD ZNF287	5.14e-05	197	148	6	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF NAV3 PEAK1 NOS3	5.14e-05	197	148	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF SEMA5B NAV3 NOS3	5.28e-05	198	148	6	07701c73137947ed4a27e225975329235bbb8734
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF366 SPTBN1 DYSF ADAMTS9 KIF17 NOS3	5.28e-05	198	148	6	ff8a9adc1302a4679ccdfe9ef95ef53e4c7a5391
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF SEMA5B NAV3 NOS3	5.28e-05	198	148	6	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF366 SPTBN1 DYSF ADAMTS9 KIF17 NOS3	5.28e-05	198	148	6	09e452742aed9f48bf1ffc35c6b06a296bcfe076
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF366 SPTBN1 DYSF ADAMTS9 KIF17 NOS3	5.28e-05	198	148	6	4a70a1ab40fe30b90acd97e4e36067db62acc905
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 SPTBN1 DYSF SEMA5B NAV3 NOS3	5.28e-05	198	148	6	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TTC14 ARFGEF1 PARP14 DDX5 CEP78 PHF3	5.43e-05	199	148	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Transverse-T_cell-Tfh\|T_cell / Region, Cell class and subclass	DLGAP1 TBC1D2 NSD1 AGO1 ZNF287 B4GALT4	5.43e-05	199	148	6	33ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SPTBN1 PARP14 ACE JAK1 ADAMTS9 KMT2A	5.58e-05	200	148	6	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTBN1 PARP14 ACE JAK1 ADAMTS9 KMT2A	5.58e-05	200	148	6	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DAZL GLI1 LRP1 CFAP61 ELMOD1	9.48e-05	137	148	5	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BTBD3 ZNF77 ZNF534 PEAK1 B4GALT4	1.05e-04	140	148	5	a88dbe7bf3e1419e360ab0b8cf24681d3424c3a7
Drug	cholesteryl ether	CLTCL1 TF LIPC CLTC LRP1	3.90e-07	24	146	5	CID000296867
Drug	AC1OAR8J	CLTCL1 TF CLTC	1.03e-06	4	146	3	CID006834124
Disease	Weaver syndrome	NSD1 KMT2A SUZ12	9.94e-07	5	138	3	C0265210
Disease	lysophosphatidylethanolamine 18:1 measurement	LRP1B LIPC UBE2E1 MUSK	1.90e-05	34	138	4	EFO_0010368
Disease	lysophosphatidylethanolamine 18:0 measurement	MATN2 LIPC ADAMTS16	4.37e-05	15	138	3	EFO_0010367
Disease	hepatitis (implicated_via_orthology)	TF LIPC	6.49e-05	3	138	2	DOID:2237 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	RNF168 ETFDH NSD1 DGKG TF LIPC SLC12A3 GLI1 ZNF483 LRP1 KMT2A CNOT1 MUSK	1.81e-04	848	138	13	EFO_0004614
Disease	unipolar depression, neuroticism measurement	ZNF366 PHF3 ARHGAP21	1.89e-04	24	138	3	EFO_0003761, EFO_0007660
Disease	nephritis (is_implicated_in)	ACE NOS3	2.15e-04	5	138	2	DOID:10952 (is_implicated_in)
Disease	Fabry disease (is_implicated_in)	ACE VDR	2.15e-04	5	138	2	DOID:14499 (is_implicated_in)
Disease	limb ischemia (implicated_via_orthology)	CS NOS3	2.15e-04	5	138	2	DOID:0050852 (implicated_via_orthology)
Disease	Carcinoma, Granular Cell	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0205644
Disease	Adenocarcinoma, Tubular	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0205645
Disease	Adenocarcinoma, Oxyphilic	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0205642
Disease	Carcinoma, Cribriform	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0205643
Disease	Adenocarcinoma, Basal Cell	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0205641
Disease	Adenocarcinoma	DAPK1 ACE KMT2A NOS3 DNMT1	2.20e-04	116	138	5	C0001418
Disease	retinal degeneration (biomarker_via_orthology)	BARD1 NOS3 VDR	3.01e-04	28	138	3	DOID:8466 (biomarker_via_orthology)
Disease	Respiratory Tract Diseases	DAPK1 ACE	3.22e-04	6	138	2	C0035242
Disease	1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6) measurement	LIPC MUSK	3.22e-04	6	138	2	EFO_0800471
Disease	1-palmitoyl-2-dihomo-linolenoyl-GPE (16:0/20:3) measurement	LIPC MUSK	3.22e-04	6	138	2	EFO_0800444
Disease	Congenital Pain Insensitivity	CLTCL1 PRDM12	4.49e-04	7	138	2	C0002768
Disease	level of Phosphatidylcholine (18:2_20:3) in blood serum	LIPC MUSK	4.49e-04	7	138	2	OBA_2045108
Disease	level of Phosphatidylcholine (18:2_20:4) in blood serum	ABHD2 LIPC	4.49e-04	7	138	2	OBA_2045109
Disease	1-oleoyl-2-arachidonoyl-GPE (18:1/20:4) measurement	LIPC MUSK	4.49e-04	7	138	2	EFO_0800470
Disease	1-oleoyl-2-linoleoyl-GPE (18:1/18:2) measurement	LIPC MUSK	4.49e-04	7	138	2	EFO_0800443
Disease	level of Phosphatidylcholine (17:0_18:2) in blood serum	LIPC MUSK	4.49e-04	7	138	2	OBA_2045086
Disease	liver cirrhosis (biomarker_via_orthology)	ACE NOS3 DNMT1	5.39e-04	34	138	3	DOID:5082 (biomarker_via_orthology)
Disease	2-arachidonoyl-GPE (20:4) measurement	LIPC MUSK	5.97e-04	8	138	2	EFO_0800260
Disease	bone measurement	IRAK1BP1 ZNF483	5.97e-04	8	138	2	EFO_0004512
Disease	1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6) measurement	ABHD2 MUSK	5.97e-04	8	138	2	EFO_0800450
Disease	Behcet's disease (is_implicated_in)	ACE NOS3 VDR	6.38e-04	36	138	3	DOID:13241 (is_implicated_in)
Disease	1-arachidonoyl-GPE (20:4n6) measurement	LIPC MUSK	7.65e-04	9	138	2	EFO_0800248
Disease	octanoylcarnitine measurement	COL27A1 ETFDH	7.65e-04	9	138	2	EFO_0021042
Disease	1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) measurement	LIPC MUSK	7.65e-04	9	138	2	EFO_0800409
Disease	1-stearoyl-2-arachidonoyl-GPE (18:0/20:4) measurement	LIPC MUSK	7.65e-04	9	138	2	EFO_0800403
Disease	1-palmitoyl-2-linoleoyl-GPE (16:0/18:2) measurement	LIPC MUSK	7.65e-04	9	138	2	EFO_0800272
Disease	X-17653 measurement	ACOT6 HELLS	7.65e-04	9	138	2	EFO_0800783
Disease	Carcinoma, Transitional Cell	DAPK1 KMT2A VDR	9.37e-04	41	138	3	C0007138
Disease	1-palmitoyl-2-oleoyl-GPE (16:0/18:1) measurement	LIPC MUSK	9.53e-04	10	138	2	EFO_0800608
Disease	1-stearoyl-2-linoleoyl-GPE (18:0/18:2) measurement	LIPC MUSK	9.53e-04	10	138	2	EFO_0800402
Disease	cholesteryl ester 22:5 measurement	LIPC MUSK	9.53e-04	10	138	2	EFO_0021444
Disease	aspartate aminotransferase measurement	ZNF366 MARK3 SUN1 ETFDH NSD1 POLR1G TMEFF1 DGLUCY LIPC ADAMTS9 GLI1 MYO15A	1.14e-03	904	138	12	EFO_0004736
Disease	Posterior Choroidal Artery Infarction	NOS3 VDR	1.16e-03	11	138	2	C0887799
Disease	Cerebral Infarction, Left Hemisphere	NOS3 VDR	1.16e-03	11	138	2	C0751010
Disease	Anterior Choroidal Artery Infarction	NOS3 VDR	1.16e-03	11	138	2	C0751012
Disease	Cerebral Infarction, Right Hemisphere	NOS3 VDR	1.16e-03	11	138	2	C0751011
Disease	Subcortical Infarction	NOS3 VDR	1.16e-03	11	138	2	C0751014
Disease	1-stearoyl-2-oleoyl-GPE (18:0/18:1) measurement	LIPC MUSK	1.16e-03	11	138	2	EFO_0800269
Disease	Cerebral Infarction	NOS3 VDR	1.16e-03	11	138	2	C0007785
Disease	smoking status measurement, forced expiratory volume	PSG11 DGKG	1.16e-03	11	138	2	EFO_0004314, EFO_0006527
Disease	obstructive sleep apnea (is_implicated_in)	ACE NOS3	1.16e-03	11	138	2	DOID:0050848 (is_implicated_in)
Disease	myocardial infarction (is_implicated_in)	ISL1 ACE LRP1 NOS3	1.22e-03	99	138	4	DOID:5844 (is_implicated_in)
Disease	coronary artery disease (is_implicated_in)	ACE LIPC NOS3 VDR	1.27e-03	100	138	4	DOID:3393 (is_implicated_in)
Disease	metabolite measurement, body weight gain	DNAI2 MUSK	1.39e-03	12	138	2	EFO_0004566, EFO_0004725
Disease	decanoylcarnitine measurement	COL27A1 ETFDH	1.39e-03	12	138	2	EFO_0021039
Disease	1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement	LIPC MUSK	1.39e-03	12	138	2	EFO_0800466
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	LIPC MUSK	1.39e-03	12	138	2	OBA_2045157
Disease	level of Phosphatidylcholine (16:0_20:2) in blood serum	LIPC MUSK	1.39e-03	12	138	2	OBA_2045074
Disease	congestive heart failure (biomarker_via_orthology)	ACE CS NOS3 DNMT1	1.63e-03	107	138	4	DOID:6000 (biomarker_via_orthology)
Disease	liver cirrhosis (implicated_via_orthology)	FOCAD NOS3	1.64e-03	13	138	2	DOID:5082 (implicated_via_orthology)
Disease	methylcobalamin deficiency type cblE, response to antineoplastic agent	MATN2 KMT2A	1.64e-03	13	138	2	GO_0097327, MONDO_0009354
Disease	hypothyroidism (implicated_via_orthology)	LIPC CS	1.64e-03	13	138	2	DOID:1459 (implicated_via_orthology)
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	LIPC MUSK	1.64e-03	13	138	2	OBA_2045072
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	LIPC MUSK	1.64e-03	13	138	2	OBA_2045082
Disease	gallbladder cancer (is_implicated_in)	LRP1B GLI1	1.64e-03	13	138	2	DOID:3121 (is_implicated_in)
Disease	hepatocellular carcinoma (is_implicated_in)	KMT2B ACE LRP1B JAK1 VDR	1.65e-03	181	138	5	DOID:684 (is_implicated_in)
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	LIPC CFAP61 MUSK	1.67e-03	50	138	3	EFO_0010732
Disease	diabetic retinopathy (is_implicated_in)	ACE NOS3 VDR	1.67e-03	50	138	3	DOID:8947 (is_implicated_in)
Disease	Malignant mesothelioma	COPG1 TF AGO1 FGD6	1.74e-03	109	138	4	C0345967
Disease	sitting height ratio	NSD1 KLHL29 JAK1	1.77e-03	51	138	3	EFO_0007118
Disease	free cholesterol to total lipids in small HDL percentage	ETFDH LIPC MUSK	1.77e-03	51	138	3	EFO_0022285
Disease	S-6-hydroxywarfarin measurement	COL27A1 PARP14 DYSF UBOX5 KMT2A PEAK1 VDR	1.78e-03	368	138	7	EFO_0803326
Disease	myocarditis (implicated_via_orthology)	ACE PPA2	1.90e-03	14	138	2	DOID:820 (implicated_via_orthology)
Disease	atrial fibrillation (is_implicated_in)	ISL1 ACE	1.90e-03	14	138	2	DOID:0060224 (is_implicated_in)
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	LIPC MUSK	1.90e-03	14	138	2	OBA_2045100
Disease	level of Phosphatidylethanolamine (18:1_18:1) in blood serum	LIPC MUSK	1.90e-03	14	138	2	OBA_2045142
Disease	lysophosphatidylcholine 15:0 measurement	LRP1B LIPC	1.90e-03	14	138	2	EFO_0020941
Disease	anemia (is_implicated_in)	ACE TF	1.90e-03	14	138	2	DOID:2355 (is_implicated_in)
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	LIPC MUSK	2.19e-03	15	138	2	OBA_2045131
Disease	level of Phosphatidylcholine (16:0_16:0) in blood serum	LIPC MUSK	2.19e-03	15	138	2	OBA_2045067
Disease	Diffuse Large B-Cell Lymphoma	TRAF5 GLI1 CLTC	2.20e-03	55	138	3	C0079744
Disease	HOMA-B	SPTBN1 NAV3 MUSK	2.20e-03	55	138	3	EFO_0004469
Disease	free cholesterol to total lipids in very large HDL percentage	ETFDH LIPC MUSK	2.20e-03	55	138	3	EFO_0022288
Disease	ovarian cancer (is_implicated_in)	BARD1 JAK1 NOS3	2.31e-03	56	138	3	DOID:2394 (is_implicated_in)
Disease	peak expiratory flow	ISL2 DYSF KLHL29 VSTM4 TBCK LRP1 SUZ12 VDR	2.44e-03	498	138	8	EFO_0009718
Disease	coronary thrombosis, GM11992	TMEM229A PALLD	2.50e-03	16	138	2	EFO_0001124, EFO_1000883
Disease	pneumonia (is_implicated_in)	ACE VDR	2.50e-03	16	138	2	DOID:552 (is_implicated_in)
Disease	Pre-Eclampsia	ACE NOS3	2.50e-03	16	138	2	C0032914
Disease	level of Phosphatidylcholine (18:0_18:2) in blood serum	LIPC MUSK	2.50e-03	16	138	2	OBA_2045090
Disease	Prostatic Neoplasms	TBC1D2 ACE LRP1B JAK1 KMT2A NOS3 DNMT1 VDR B4GALT4	2.52e-03	616	138	9	C0033578
Disease	Malignant neoplasm of prostate	TBC1D2 ACE LRP1B JAK1 KMT2A NOS3 DNMT1 VDR B4GALT4	2.52e-03	616	138	9	C0376358
Disease	serum alanine aminotransferase measurement	DLGAP1 MARK3 COL27A1 DGLUCY LIPC ADAMTS9 P4HA1 CNOT1 MUSK SENP7 DNMT1	2.64e-03	869	138	11	EFO_0004735
Disease	free cholesterol to total lipids in medium HDL percentage	ETFDH LIPC MUSK	2.82e-03	60	138	3	EFO_0022282
Disease	Uremia	NOS3 VDR	2.82e-03	17	138	2	C0041948
Disease	Lipidemias	LIPC NOS3	2.82e-03	17	138	2	C1706412
Disease	Hyperlipidemia	LIPC NOS3	2.82e-03	17	138	2	C0020473
Disease	optic disc size measurement	TSPAN11 MARK3 LRP1B NAV3 ARHGAP21	2.83e-03	205	138	5	EFO_0004832
Disease	pancreatic ductal carcinoma (is_marker_for)	ACE PALLD DNMT1	2.95e-03	61	138	3	DOID:3587 (is_marker_for)
Disease	alkaline phosphatase measurement	ZNF366 SPTBN1 JAK1 KIF9 LIPC CELA3A KIF17 CNOT1 ARHGAP21 MUSK SENP7 DNMT1	2.97e-03	1015	138	12	EFO_0004533
Disease	syndrome (implicated_via_orthology)	NSD1 CNOT1	3.16e-03	18	138	2	DOID:225 (implicated_via_orthology)
Disease	essential hypertension (is_implicated_in)	SLC12A3 NOS3	3.16e-03	18	138	2	DOID:10825 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFNGDCRITKDNRRH	VDR	61	P11473
RLQAHGRRKPQIICY	ACOT1	341	Q86TX2
CNLDISNKYGRTPLH	DAPK1	601	P53355
NSSQRRYTGKVPCNH	CFAP61	796	Q8NHU2
ELQRICYNTKPGASR	ELMOD1	36	Q8N336
DLCNYHPERVRQGKV	BARD1	741	Q99728
RGAQYQPILRDHICK	DNMT1	1401	P26358
EGPLHQCDIYRSTKA	ACE	551	P12821
GRYRPQECKALQRVA	B4GALT4	111	O60513
CPGIANHSEKQYIRT	ABHD2	131	P08910
LIRHCAKYVSDRPQA	ARFGEF1	1346	Q9Y6D6
KYRVCNVTRRPASHQ	AGO1	276	Q9UL18
RLQAHGKERPQIICY	ACOT6	341	Q3I5F7
ARKGLVPQRCHRFQS	BTBD3	366	Q9Y2F9
PRRHYTSQQELKDEC	DLGAP1	71	O14490
HRGFPLIKTRDICNQ	CEP78	401	Q5JTW2
HPDGNRKLAVAYSCL	DNAI2	171	Q9GZS0
LCEHKYGNAPRVRIN	BCKDK	241	O14874
GTQACRKTQPNIHDY	ARMCX4	1081	Q5H9R4
GAQSRPVQCTRRVHY	ADAMTS16	946	Q8TE57
HSGVYVCRANKPRTR	IGDCC4	306	Q8TDY8
VYHADCLNLTKRPAG	NSD1	2141	Q96L73
HGPICTEYAINKLRQ	JAK1	441	P23458
NRYGDVPCLDQTRVK	PTPN9	331	P43378
PAVRTGLYCRDQAHA	ANO7	21	Q6IWH7
NLKVRHQRTEECYLP	OVOS1	371	Q6IE37
YLREQHARCKNPVAT	DCAF1	1011	Q9Y4B6
DRCHRIGQTKPVVVY	HELLS	706	Q9NRZ9
YHTPGSVENLRRQAC	IRAK1BP1	161	Q5VVH5
IYQKRTQPTVRSHAC	LRP1B	461	Q9NZR2
RRINYCALNKPGCEH	MATN2	401	O00339
QCNSFYIPRHIRKEE	GREM1	121	O60565
NRGQHVCPLSRRAYI	MYO15A	3261	Q9UKN7
LNSHVKETTRGPRYC	MTO1	301	Q9Y2Z2
PRVRSHACENDQYGK	LRP1	471	Q07954
YRRSKEITVRGHNCP	DDX5	76	P17844
QHGKSPDLYERQVCL	PEAK1	1481	Q9H792
RQNGPVIYKHRSRIC	NAV3	1776	Q8IVL0
CNTLGYHVRQEPRSK	LIPC	321	P11150
SQCPRLEHYGQVQVK	GLI1	801	P08151
PHGAARAEVYLRKCT	KMT2B	2506	Q9UMN6
ALGDQKRDHIPFRQC	KIF9	281	Q9HAQ2
YPGKVREARCQASVH	POMGNT2	481	Q8NAT1
RLHTGERPYKCQVCQ	PRDM12	291	Q9H4Q4
SRYRGQEHCLHPKLQ	CXCL14	76	O95715
KTRHVLQCQARGNPY	ICAM3	416	P32942
EIGTRNLCDPHRYNI	NOS3	361	P29474
EIQRINEHPYRKCSD	DCHS2	3106	Q6V1P9
YSTRHAACPVLVGNK	P4HA1	496	P13674
EREVKSPGARHCYQD	PALLD	231	Q8WX93
NSKDDLPYCLRRIHG	PAN3	511	Q58A45
YDRVTQHLCLKGPSA	PARP14	501	Q460N5
PNDGRCHLEDNLYKR	ITGB2	281	P05107
KYTVHERCVSRNIPG	DGKG	306	P49619
HPLYNRVKTGQIANC	FZD8	246	Q9H461
KELYSVRNIRPSCHG	ETFDH	446	Q16134
IGTHKIARETECNPY	ADAMTS9	1526	Q9P2N4
YHICAKLANVRAVPG	DMAP1	196	Q9NPF5
CYQSPALEGVRKEHQ	FITM2	121	Q8N6M3
QQARLPVVDYKHCSR	CELA3A	176	P09093
GHAVLRKTDPRYTCQ	CS	346	O75390
HLRKQCGQADTYQSP	COL27A1	231	Q8IZC6
VQSVEKPQYRGTLHC	SLC25A29	31	Q8N8R3
CADEQPHIGNYRLLK	MARK3	46	P27448
IPKSEDRRYCNSHLQ	INO80D	66	Q53TQ3
PNCYSRVINIDGQKH	KMT2A	3911	Q03164
KEDNYRGPAVRALCQ	COPG1	116	Q9Y678
KVNLGHAARTVCYSP	EML5	1731	Q05BV3
GPAIRKQNLCAYHVQ	DAZL	111	Q92904
CAVHSQYLRKAVGPS	DGLUCY	536	Q7Z3D6
ITPKHNGLYACSARN	PSG11	291	Q9UQ72
QLPDRCTLKTGHYNI	SEC22A	46	Q96IW7
CQQHRVKAPVYRTDR	DYSF	1706	O75923
IRDICKQRPYQHGAD	FOCAD	591	Q5VW36
IDNCYHRAAEGRAPK	PANX2	161	Q96RD6
GRKYTLRCHVTQVFP	ICAM4	146	Q14773
KQLHTLRTCYAANPR	ISL2	201	Q96A47
ALVDGRCKHVPYRDS	KIF17	276	Q9P2E2
AAHNKCPRDGRFVEQ	MRPS16	36	Q9Y3D3
RPRIHCNKISADGYE	UBOX5	11	O94941
NPHKSCYLSERGSQR	SENP7	216	Q9BQF6
DRPKCQGLESRIQHF	PUS3	416	Q9BZE2
RPQRCAQVLHVDYGR	TDRD6	336	O60522
HFALEKVYLQQRRCP	TMEM229A	101	B2RXF0
AENKQLRRAGCPYQA	RIMBP3	396	Q9UFD9
LANYTCHVENRNGRK	IL1RAPL2	326	Q9NP60
IRHCSQRYGKLKPQV	RHBDF1	106	Q96CC6
KRHRYRVLSSCPQAG	POLR1G	76	O15446
PLCRKNQYQTRVIHD	RNF32	166	Q9H0A6
THQEQGRSYKEVCAP	HERC2P3	221	Q9BVR0
KQLHTLRTCYAANPR	ISL1	191	P61371
HTEERGQPCSQNYRL	PPA2	36	Q9H2U2
TLNCQNSYVEPHKIR	SPG21	201	Q9NZD8
GDAIKPYIVHRCRQS	PI4KB	191	Q9UBF8
HYGCAVTDKRRNLQQ	TRAF5	226	O00463
YKPCDPQVIRDRVAH	SPTBN1	601	Q01082
KRDPHLACVAYERGQ	CLTC	911	Q00610
KRDPHLACVAYERGQ	CLTCL1	911	P53675
KHARQEGRRYCDPVV	CNOT1	1531	A5YKK6
AKYPEHQQRCRDEIR	CYP4Z1	331	Q86W10
TNHQRIHTGERPYKC	ZNF610	416	Q8N9Z0
RHYLCNRPVGSDQKA	UHRF1BP1L	1231	A0JNW5
HQKISRQKPRECQEY	ZNF30	111	P17039
KHRNVRTGERPYECS	ZNF586	111	Q9NXT0
QQHTRIHTGDRPYKC	ZNF384	361	Q8TF68
FENRQRSHTGQRPCK	ZNF77	151	Q15935
NNGCLVSPHIREKTY	ZNF616	171	Q08AN1
QHQRIHTGEKPYACR	ZNF287	721	Q9HBT7
TRKPVEEYANCHLAR	TF	586	P02787
CGHSYNVTQRRPRVL	RNF208	146	Q9H0X6
HPKGARIDVSINECY	SUZ12	481	Q15022
HGRTLKRYPCRQCEQ	ZNF592	1006	Q92610
GLDYLKNQPARVCEH	FGD6	1261	Q6ZV73
ACYLTNHGRRIPKDV	SMOX	121	Q9NWM0
VQHQRLHSGKRPYEC	ZNF470	581	Q6ECI4
QHRRVHTGKRPYQCS	ZNF211	526	Q13398
QHRNIHTGVKPYSCN	ZNF534	636	Q76KX8
PEYHKENRRCSRNSG	PHF3	191	Q92576
DHIKNYRPQCLVLTG	SLC12A3	636	P55017
LALENCPTHRNARKY	TTC14	366	Q96N46
EKINGVARCPYDPRH	SEMA5B	221	Q9P283
SYDRNICQKRVPLGE	PKHD1L1	2596	Q86WI1
PRLCQYVDISRGKHE	TBCK	51	Q8TEA7
RCGQRAHPSNIYKVE	TSPAN11	191	A1L157
ERHPGDSKNYNECIR	UBE2Z	231	Q9H832
QKHYPRECKLRASGQ	RNF168	81	Q8IYW5
TNHQRIHTGERPYKC	ZNF480	471	Q8WV37
RKPGCCRSQSLHYQE	TMEM253	161	P0C7T8
QEVTLRCKPISGHDY	TRBV12-4	36	A0A0B4J2E0
KRHLTTHRGPIQYNC	ZNF366	381	Q8N895
QKVTPRRYGKCEHEN	ZNF681	96	Q96N22
ECGKAFNQRPTLIRH	ZNF792	566	Q3KQV3
LHQRVHTGERPYNCK	ZNF230	381	Q9UIE0
PHQRVSTGENLYRCQ	ZNF233	331	A6NK53
RHQRIHTGEKPYLCN	ZNF483	596	Q8TF39
SRHQRIHTGEKPYQC	ZNF420	631	Q8TAQ5
RVRHYLVKCPQNSSG	VSTM4	211	Q8IW00
GPVSRVYSRDRNQKC	SUN1	206	O94901
QEQKAHIRRKPYECN	ZNF766	176	Q5HY98
HIRRKPYECNEQGKV	ZNF766	181	Q5HY98
HQKEITVIARGPCYS	TMEFF1	131	Q8IYR6
NHQRIHTGEKPYRCL	ZNF354B	511	Q96LW1
PKVTFRTRIYHCNIN	UBE2E1	111	P51965
CERPRQQEIHKSFRG	ARHGAP21	541	Q5T5U3
RGHRNKVTCLLYPHQ	WDR7	461	Q9Y4E6
IVHQRVHNGARPYKC	ZNF134	276	P52741
CYQELLSRGQAREHP	TBC1D2	651	Q9BYX2
QNLEEGYSLRHQCPR	ZBTB6	291	Q15916
RHQRTHTGEKPYQCN	ZNF263	451	O14978
VPRCRHNSLVYDGKI	KLHL29	671	Q96CT2
RIHNVQKEDAGQYRC	MUSK	176	O15146