Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PSAT1 OFD1 SUN1 RALGAPB LETM1 TAB3 NCOR2 PPP2R3A MTMR7 UBA1 PHLPP1 STIP1 CDC25A YME1L1 KDM6A NOTCH1	5.48e-07	1049	118	16	27880917
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBA5 DTX3 RSPRY1 UBA1 HECW2 ANKIB1	9.12e-07	95	118	6	29643511
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	MYLK DNAH2 PLXNB2 LRP1B MTMR7 UBA1 LATS1 HECW2 PRMT1 PLCB3 PLCL1 CDC25A KCNH5	1.27e-06	730	118	13	34857952
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	NAA15 DOCK11 PSMB1 TUB RABL6 NCOR2 RTRAF PLCB3 CHD6 STK24	5.38e-06	475	118	10	31040226
Pubmed	Physiological and pathophysiological characteristics of ataxin-3 isoforms.	PSAT1 MYH9 PSMB1 UBA1 RTRAF PRMT1 STIP1 HSPA1L	5.58e-06	281	118	8	30455355
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP85L POLG TTLL5 NCAPH2 LRP1B SATB1 SACS RTRAF DAAM2 YY1AP1 CHD6 ZNF84 CTSL YME1L1 KDM6A SOS1	7.41e-06	1285	118	16	35914814
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SLC12A6 MYH9 MYLK DNAH2 APOB PABPC5 NEB LETM1 RYR2 NUP54 LATS1 SACS ETHE1 ITSN2 CHD6 ZNF84 HSPA1L	7.66e-06	1442	118	17	35575683
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	OFD1 PSMB1 NCAPH2 CCDC122 RSPRY1 EHD3 UBA1 TMEM120A DDHD1 PRMT1 HSPA1L MUC5AC YME1L1 NUP160 INVS DNPEP	1.04e-05	1321	118	16	27173435
Pubmed	Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin.	ARF1 ARF3	1.14e-05	2	118	2	2474826
Pubmed	Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca2+ leakage promote cardiac contractile dysfunction in sepsis.	RYR2 TLR4	1.14e-05	2	118	2	29150444
Pubmed	Long-term bezafibrate treatment improves skin and spleen phenotypes of the mtDNA mutator mouse.	POLG TLR4	1.14e-05	2	118	2	22962610
Pubmed	Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.	ARF1 ARF3	1.14e-05	2	118	2	1577740
Pubmed	Assignment of human ADP ribosylation factor (ARF) genes ARF1 and ARF3 to chromosomes 1q42 and 12q13, respectively.	ARF1 ARF3	1.14e-05	2	118	2	8661066
Pubmed	Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves.	TLR4 NOTCH1	1.14e-05	2	118	2	22965987
Pubmed	Crosstalk between TLR4 and Notch1 signaling in the IgA nephropathy during inflammatory response.	TLR4 NOTCH1	1.14e-05	2	118	2	29230705
Pubmed	Exome sequencing: an efficient diagnostic tool for complex neurodegenerative disorders.	APOB SACS	1.14e-05	2	118	2	23043354
Pubmed	ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway.	ARF1 ARF3	1.14e-05	2	118	2	22971977
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	UBA5 PSAT1 MYH9 NAA15 PSMB1 GBP1 RABL6 UBA1 RTRAF PRMT1 PLCB3 STIP1 HSPA1L STK24 NUP160 DNPEP	3.38e-05	1455	118	16	22863883
Pubmed	MUC5AC expression through bidirectional communication of Notch and epidermal growth factor receptor pathways.	MUC5AC NOTCH1	3.42e-05	3	118	2	21622856
Pubmed	Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor.	MYH9 TLR4	3.42e-05	3	118	2	28153611
Pubmed	ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.	ARF1 ARF3	3.42e-05	3	118	2	23783033
Pubmed	Hyperphosphorylation and association with RBP of the intracellular domain of Notch1.	RBP3 NOTCH1	3.42e-05	3	118	2	11511084
Pubmed	Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression.	MYLK TLR4	3.42e-05	3	118	2	29157665
Pubmed	CUL4A promotes proliferation and inhibits apoptosis of colon cancer cells via regulating Hippo pathway.	LATS1 YY1AP1	3.42e-05	3	118	2	33155207
Pubmed	Stabilin receptors clear LPS and control systemic inflammation.	STAB2 TLR4	3.42e-05	3	118	2	34816100
Pubmed	Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.	ARF1 ARF3	3.42e-05	3	118	2	26330566
Pubmed	Differential expression of flectin in the extracellular matrix and left-right asymmetry in mouse embryonic heart during looping stages.	MYH9 INVS	3.42e-05	3	118	2	9842715
Pubmed	The Critical Role of Notch1-TLR 4 Signaling in the Inflammatory and Fungicidal Activity of Macrophages Against Paracoccidioides brasiliensis Strain Pb18.	TLR4 NOTCH1	3.42e-05	3	118	2	28600728
Pubmed	Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.	ARF1 ARF3	3.42e-05	3	118	2	10623590
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	OFD1 CEP85L TTLL5 LRP1B TAB3 ARF1 ARF3 PPP2R3A LATS1 ITSN2 NFKBIE CLEC16A	3.48e-05	853	118	12	28718761
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYH9 DOCK11 DNAH2 TIGD4 ICE1 CPT1B MYO15B HECW2 PLCB3 STIP1 CHD6	4.36e-05	736	118	11	29676528
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	NAA15 SUN1 LETM1 ARF1 ARF3 UBA1 RTRAF PRMT1 STIP1 NUP160	4.39e-05	607	118	10	39147351
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ARF3 STAC2 PPP2R3A UBA1 SACS SECISBP2 PRMT1 YY1AP1 CHD6 NOTCH1	4.45e-05	608	118	10	16713569
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DNAH2 NEB RYR2 NCOR2 DDHD1 ITSN2 CHD6 CCDC102B YME1L1 KDM6A	6.64e-05	638	118	10	31182584
Pubmed	Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response.	LYSMD3 ZFP69B	6.82e-05	4	118	2	29851555
Pubmed	Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.	NCOR2 NOTCH1	6.82e-05	4	118	2	22888005
Pubmed	Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.	TLR4 NOTCH1	6.82e-05	4	118	2	31189722
Pubmed	SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.	NCOR2 NOTCH1	6.82e-05	4	118	2	10713164
Pubmed	Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages.	RBP3 TLR4	6.82e-05	4	118	2	7822029
Pubmed	Crosstalk between Toll-like receptor 3 and Notch signaling contributes to CD14+ monocytes activity in enterovirus 71 infected hand, foot, and mouth disease.	TLR4 NOTCH1	6.82e-05	4	118	2	29702280
Pubmed	Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.	DTX3 NOTCH1	6.82e-05	4	118	2	11226752
Pubmed	Notch signaling is activated by TLR stimulation and regulates macrophage functions.	TLR4 NOTCH1	6.82e-05	4	118	2	18085664
Pubmed	Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint.	NCOR2 TLR4	6.82e-05	4	118	2	19595715
Pubmed	Interaction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulin.	NEB SOS1	6.82e-05	4	118	2	12482578
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	NAA15 RALGAPB LETM1 RSPRY1 UPF2 DDHD1 ANKIB1 YY1AP1 PLCB3 CLEC16A	7.75e-05	650	118	10	38777146
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PSAT1 MYH9 RALGAPB NCAPH2 CCDC122 PLXNB2 HECW2 DDHD1 SECISBP2 PRMT1 DAAM2 TRAM2 XKRX DNPEP	8.39e-05	1242	118	14	30973865
Pubmed	Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.	NEB RYR2 PLCB3	1.05e-04	27	118	3	18468998
Pubmed	Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.	ARF1 ARF3	1.13e-04	5	118	2	9038142
Pubmed	Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IRA Signal in Malignant Mesothelioma.	DTX3 UBA1	1.13e-04	5	118	2	37108544
Pubmed	A novel role for IkappaB kinase (IKK) alpha and IKKbeta in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae.	TLR4 MUC5AC	1.13e-04	5	118	2	17237423
Pubmed	FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression.	RTRAF PRMT1	1.13e-04	5	118	2	28040436
Pubmed	UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.	KDM6A NOTCH1	1.13e-04	5	118	2	29073101
Pubmed	ADP-ribosylation factor is functionally and physically associated with the Golgi complex.	ARF1 ARF3	1.13e-04	5	118	2	2105501
Pubmed	Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.	NCOR2 NOTCH1	1.13e-04	5	118	2	21475249
Pubmed	Telokin expression is restricted to smooth muscle tissues during mouse development.	MYH9 MYLK	1.13e-04	5	118	2	11121372
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	PSAT1 MYH9 RBP3 VAT1L ARF3 UBA1 RTRAF STIP1 DNPEP	1.16e-04	552	118	9	36293380
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	OFD1 DOCK11 RALGAPB LETM1 LATS1 STK24 NUP160 NOTCH1	1.47e-04	446	118	8	24255178
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SLC12A6 PSAT1 POLG RALGAPB EHD3 NCOR2 PPP2R3A ANKIB1 CHD6 ZNF84 ZDHHC13 CLEC16A SCARA3 KDM6A INVS	1.60e-04	1489	118	15	28611215
Pubmed	Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth.	SACS HSPA1L	1.70e-04	6	118	2	34429451
Pubmed	The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.	NCOR2 NOTCH1	1.70e-04	6	118	2	11404076
Pubmed	Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X.	TSNAXIP1 SUN1	1.70e-04	6	118	2	12036294
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ROGDI NCOR2 RTRAF NUP160 SOS1	1.70e-04	151	118	5	17043677
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	UPF2 HECW2 ANKIB1 CHD6 EBF4	1.81e-04	153	118	5	10718198
Pubmed	Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.	PLCB3 SOS1	2.37e-04	7	118	2	30720883
Pubmed	GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.	ARF1 ARF3	2.37e-04	7	118	2	11950392
Pubmed	A human MAP kinase interactome.	MYH9 NEB NUP54 LATS1 ITSN2 YY1AP1 CHD6 SOS1	2.63e-04	486	118	8	20936779
Pubmed	Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.	PSAT1 LRP1B DNPEP	2.95e-04	38	118	3	29799838
Pubmed	Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.	PSAT1 MYH9 PSMB1 ARF1 UBA1 RTRAF PRMT1	3.13e-04	377	118	7	25147182
Pubmed	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).	ARF1 ARF3	3.15e-04	8	118	2	8947846
Pubmed	Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia.	TLR4 CTSL	3.15e-04	8	118	2	31611307
Pubmed	Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein.	TLR4 KCNH5	3.15e-04	8	118	2	10524757
Pubmed	MKP1 regulates the induction of MUC5AC mucin by Streptococcus pneumoniae pneumolysin by inhibiting the PAK4-JNK signaling pathway.	TLR4 MUC5AC	3.15e-04	8	118	2	18782768
Pubmed	Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.	MYH9 MYLK	3.15e-04	8	118	2	17429076
Pubmed	Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development.	ARF1 ARF3	3.15e-04	8	118	2	38227057
Pubmed	Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells.	ARF1 ARF3	3.15e-04	8	118	2	8195219
Pubmed	Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.	ARF1 UPF2	3.15e-04	8	118	2	15680326
Pubmed	Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade.	TLR4 NOTCH1	3.15e-04	8	118	2	25825216
Pubmed	Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.	TLR4 CTSL	3.15e-04	8	118	2	22916010
Pubmed	A proteomic snapshot of the human heat shock protein 90 interactome.	PSAT1 MYH9 UBA1	3.43e-04	40	118	3	16263121
Pubmed	Human transcription factor protein interaction networks.	OFD1 CCDC174 PSMB1 TAB3 ARF3 NUP54 NCOR2 SATB1 NFKBIE PRMT1 YY1AP1 STIP1 CHD6 KDM6A	3.55e-04	1429	118	14	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC12A6 MYH9 RBP3 LETM1 EHD3 UBA1 UPF2 SACS HECW2 RTRAF ITSN2 STIP1 PLCL1 DNPEP	3.60e-04	1431	118	14	37142655
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	UBA5 MYH9 NAA15 LETM1 RABL6 RTRAF PRMT1 LGR6 DNPEP	3.99e-04	653	118	9	33742100
Pubmed	PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1.	MYH9 LATS1	4.05e-04	9	118	2	31605013
Pubmed	The human RNA surveillance factor UPF1 is required for S phase progression and genome stability.	POLG UPF2	4.05e-04	9	118	2	16488880
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPB VAT1L ITSN2 DAAM2 YY1AP1 CHD6 CLEC16A	4.94e-04	407	118	7	12693553
Pubmed	Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.	NCOR2 NFKBIE	5.05e-04	10	118	2	15536134
Pubmed	Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.	ARF1 ARF3	5.05e-04	10	118	2	10828067
Pubmed	NOVA2 regulates neural circRNA biogenesis.	PCMTD1 ZDHHC13	5.05e-04	10	118	2	34157123
Pubmed	A point mutation in Myh10 causes major defects in heart development and body wall closure.	MYH9 MYLK	5.05e-04	10	118	2	24825879
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	PSAT1 MYH9 NAA15 PSMB1 NCOR2 UPF2 RTRAF STIP1	5.15e-04	538	118	8	28524877
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	RBP3 DNAH2 NEB	5.54e-04	47	118	3	8812413
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	UBA5 MYH9 ZSWIM3 RALGAPB NCAPH2 UBA1 UPF2 SLC15A2 PHLPP1 PRMT1 STIP1 CDC25A SOS1	5.83e-04	1327	118	13	32694731
Pubmed	The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.	LATS1 TLR4	6.15e-04	11	118	2	27912060
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	MYH9 HSPA1L	6.15e-04	11	118	2	19015242
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MYH9 LETM1 ARF3 RABL6 UBA1 LATS1 PRMT1 STIP1 NOTCH1	7.12e-04	708	118	9	39231216
Pubmed	The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.	UBA1 HSPA1L	7.37e-04	12	118	2	24399297
Pubmed	Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network.	NUP54 RTRAF	7.37e-04	12	118	2	21994455
Pubmed	Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.	MUC5AC NOTCH1	7.37e-04	12	118	2	19369400
Pubmed	GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.	ARF1 ARF3	7.37e-04	12	118	2	30631079
Pubmed	LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.	GBP1 TLR4	7.37e-04	12	118	2	29459437
Cytoband	22q13.33	NCAPH2 CPT1B PLXNB2	1.31e-04	38	118	3	22q13.33
GeneFamily	Ubiquitin like modifier activating enzymes	UBA5 UBA1	7.09e-04	10	73	2	100
GeneFamily	EF-hand domain containing	LETM1 RYR2 EHD3 PPP2R3A ITSN2	1.92e-03	219	73	5	863
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCB3 PLCL1	2.63e-03	19	73	2	832
GeneFamily	Ankyrin repeat domain containing	NFKBIE ANKIB1 ZDHHC13 NOTCH1 INVS	2.96e-03	242	73	5	403
Coexpression	GSE4142_GC_BCELL_VS_MEMORY_BCELL_UP	UBA5 NEB PLXNB2 DYDC2 UPF2 SLC15A2 PLCL1 CLEC16A	3.35e-06	200	117	8	M6397
Coexpression	GSE25677_MPL_VS_R848_STIM_BCELL_DN	MYH9 DOCK11 ICE1 CC2D2B STAC2 SATB1 ITSN2	1.74e-05	181	117	7	M8187
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK RYR2 DAAM2 PLCL1 LGR6 CCDC102B SCARA3	7.35e-07	189	118	7	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK VAT1L RYR2 DAAM2 LGR6 CCDC102B SCARA3	7.88e-07	191	118	7	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK RYR2 DAAM2 PLCL1 LGR6 CCDC102B SCARA3	7.88e-07	191	118	7	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK RYR2 DAAM2 PLCL1 LGR6 CCDC102B SCARA3	8.17e-07	192	118	7	992d08092edbc68c47b945deb8708379738c239a
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK LRP1B RYR2 MTMR7 SACS LGR6 SCARA3	9.37e-07	196	118	7	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	control-unassigned\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FSIP1 DTX3 SATB1 ZNF84 LGR6 ZDHHC13 HSPA1L	1.04e-06	199	118	7	5db7c8089172ac8e796613b3cef618d87007a0ab
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 STAC2 DAAM2 PLCL1 LGR6 CCDC102B	1.07e-06	200	118	7	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 RYR2 DAAM2 PLCL1 LGR6 CCDC102B	1.07e-06	200	118	7	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 DTX3 RYR2 DAAM2 PLCL1 CCDC102B	1.07e-06	200	118	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A6 FSIP1 NUP54 SATB1 XKRX STK24	5.40e-06	166	118	6	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A6 FSIP1 NUP54 SATB1 XKRX STK24	5.40e-06	166	118	6	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK APOB PABPC5 LGR6 CLEC16A EBF4	7.07e-06	174	118	6	c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK LRP1B RYR2 PLCL1 LGR6 ZFP69B	8.05e-06	178	118	6	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK LRP1B RYR2 PLCL1 LGR6 ZFP69B	8.05e-06	178	118	6	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA12 APOB NEB LRP1B RYR2	9.72e-06	184	118	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA12 APOB NEB LRP1B RYR2	9.72e-06	184	118	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ABCA12 APOB NEB LRP1B RYR2	9.72e-06	184	118	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK VAT1L RYR2 DAAM2 PLCL1 CCDC102B	9.72e-06	184	118	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PSAT1 MYO15B TLR4 PHLPP1 DAAM2 NOTCH1	1.17e-05	190	118	6	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	distal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TSNAXIP1 CCDC74B ABCA12 DNAH2 TIGD4 DYDC2	1.43e-05	197	118	6	15b4d1203943ce90a7083178d4a4284d9b323071
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK LRP1B RYR2 UNC45B PLCL1 LGR6	1.47e-05	198	118	6	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	control-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FSIP1 SATB1 ZNF84 LGR6 ZDHHC13 HSPA1L	1.52e-05	199	118	6	50e2da35edff1aadef939cfbd4549f73c1a07717
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYH9 MYLK DOCK11 RYR2 DAAM2 CCDC102B	1.56e-05	200	118	6	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 RYR2 DAAM2 LGR6 CCDC102B	1.56e-05	200	118	6	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 PLXNB2 RYR2 ARF3 CCDC102B	1.56e-05	200	118	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBA5 CEP85L PLCL1 LGR6 CCDC102B	5.64e-05	154	118	5	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	LRP1B FAT2 PLCL1 LGR6 SCARA3	6.76e-05	160	118	5	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYLK TUB STAC2 LGR6 SCARA3	7.60e-05	164	118	5	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	STAB2 SLC15A2 TLR4 DAAM2 SLC25A48	8.28e-05	167	118	5	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP1B RYR2 DAAM2 PLCL1 CCDC102B	9.00e-05	170	118	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK RYR2 SACS PLCL1 LGR6	9.77e-05	173	118	5	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	LRP1B TUB SATB1 UPF2 PHLPP1	1.09e-04	177	118	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 EHD3 UNC45B HECW2 DAAM2	1.21e-04	181	118	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYLK APOB RYR2 LGR6 SCARA3	1.21e-04	181	118	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 EHD3 UNC45B HECW2 DAAM2	1.21e-04	181	118	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	Club-club-8\|World / Class top	ITPRID1 SLC15A2 LGR6 MUC5AC SCARA3	1.24e-04	182	118	5	8111d917e588008d947021460ddf8f1e7ae1337a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK11 RYR2 DAAM2 PLCL1 CCDC102B	1.27e-04	183	118	5	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	OFD1 ICE1 UBA1 SECISBP2 CHD6	1.34e-04	185	118	5	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK VAT1L STAC2 LGR6 SCARA3	1.34e-04	185	118	5	76304829fcfb5934188933ca20d33bc8c8b0dc91
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK VAT1L STAC2 LGR6 SCARA3	1.34e-04	185	118	5	0595e7ab37eed690f6e3d16a9a4e9a4bce2b89db
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	PLXNB2 CC2D2B NFKBIE YY1AP1 PLCB3	1.37e-04	186	118	5	3314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 DAAM2 PLCL1 LGR6 CCDC102B	1.37e-04	186	118	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSNAXIP1 CCDC74B SPATA6L DNAH2 DYDC2	1.37e-04	186	118	5	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 DAAM2 PLCL1 LGR6 CCDC102B	1.37e-04	186	118	5	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TLR4 DAAM2 SCARA3 SLC25A48 NOTCH1	1.41e-04	187	118	5	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TLR4 DAAM2 SCARA3 SLC25A48 NOTCH1	1.41e-04	187	118	5	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PSAT1 TLR4 DAAM2 SLC25A48 NOTCH1	1.41e-04	187	118	5	2b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK RYR2 DAAM2 LGR6 CCDC102B	1.44e-04	188	118	5	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUB RYR2 LGR6 HSPA1L SCARA3	1.44e-04	188	118	5	61f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell	droplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUB RYR2 LGR6 HSPA1L SCARA3	1.44e-04	188	118	5	7553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO15B TLR4 PHLPP1 DAAM2 NOTCH1	1.44e-04	188	118	5	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR2 UNC45B DAAM2 LGR6 SCARA3	1.48e-04	189	118	5	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VAT1L RYR2 DAAM2 LGR6 CCDC102B	1.48e-04	189	118	5	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR2 UNC45B DAAM2 LGR6 SCARA3	1.48e-04	189	118	5	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 DAAM2 PLCL1 LGR6 SCARA3	1.48e-04	189	118	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 STAC2 DAAM2 PLCL1 LGR6	1.52e-04	190	118	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 DAAM2 PLCL1 LGR6 SCARA3	1.55e-04	191	118	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO15B TLR4 PHLPP1 DAAM2 NOTCH1	1.55e-04	191	118	5	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DTX3 ARF1 PRMT1 STIP1 CTSL	1.59e-04	192	118	5	796e04365b2ea645e14d8970c8c22ff96ddd75de
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DTX3 ARF1 PRMT1 STIP1 CTSL	1.59e-04	192	118	5	0134967d36b5dac1e4646d1a555ca8bb4eeac8ef
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	RALGAPB CCDC122 ITSN2 PHLPP1 YY1AP1	1.63e-04	193	118	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	SLC12A6 STAB2 CEP85L LYSMD3 ETHE1	1.71e-04	195	118	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DNAH2 CDCP1 UPF2 TLR4 CTSL	1.71e-04	195	118	5	d53585715c7f5827c4f5a6db11cb31857ee9d4f0
ToppCell	distal-Epithelial-Proximal_Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TSNAXIP1 CCDC74B ABCA12 TIGD4 DYDC2	1.71e-04	195	118	5	abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCell	distal-Epithelial-Proximal_Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TSNAXIP1 CCDC74B ABCA12 TIGD4 DYDC2	1.71e-04	195	118	5	0e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYLK RYR2 DAAM2 LGR6 CCDC102B	1.75e-04	196	118	5	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP1 PLXNB2 TLR4 CTSL SECTM1	1.79e-04	197	118	5	383d598ce3f8f5fc98bef3300e4cf7b6992aec9c
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GBP1 PLXNB2 TLR4 CTSL SECTM1	1.79e-04	197	118	5	3cc4e56a77f96a43f9b5a24cf1b9524c927ef795
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK RYR2 DAAM2 CCDC102B SCARA3	1.79e-04	197	118	5	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK LRP1B UNC45B DAAM2 SCARA3	1.84e-04	198	118	5	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|World / disease group, cell group and cell class	GBP1 PLXNB2 TLR4 CTSL SECTM1	1.84e-04	198	118	5	8449934e20bb2a34079fb642cae0d4647b9efe51
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	TSNAXIP1 CCDC74B CCDC122 DYDC2 MYO15B	1.84e-04	198	118	5	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPATA6L FSIP1 POLG LETM1 UNC45B	1.88e-04	199	118	5	26bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	CPT1B MTMR7 SLC15A2 DDHD1 DNPEP	1.92e-04	200	118	5	401d50fa394fa863fa7836344110ae5c7af3250a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 DAAM2 PLCL1 CCDC102B	1.92e-04	200	118	5	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 RYR2 DAAM2 CCDC102B	1.92e-04	200	118	5	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK RYR2 DAAM2 CCDC102B SCARA3	1.92e-04	200	118	5	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	Sepsis-Leuk-UTI\|Sepsis / Disease, condition lineage and cell class	GBP1 PRMT1 FAM118A CTSL SECTM1	1.92e-04	200	118	5	7d92b24c0c888dd46e40b7e3c6c2645c3604f132
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK RYR2 DAAM2 CCDC102B SCARA3	1.92e-04	200	118	5	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK DOCK11 RYR2 DAAM2 CCDC102B	1.92e-04	200	118	5	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	mild-CD163+_Monocytes_(Sample_ID1_d7)\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GBP1 PLXNB2 TLR4 CTSL SECTM1	1.92e-04	200	118	5	82126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK RYR2 DAAM2 CCDC102B SCARA3	1.92e-04	200	118	5	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK RYR2 STAC2 DAAM2 CCDC102B	1.92e-04	200	118	5	7c62678cf408aaaf98d6df0fb27814d2007c4521
Disease	Congenital aneurysm of ascending aorta	MYLK NOTCH1	1.56e-05	2	117	2	C0345050
Disease	mood instability measurement	LRP1B TLR4 PLCL1 STK24 NUP160	1.61e-04	128	117	5	EFO_0008475
Disease	obesity (implicated_via_orthology)	PLXNB2 TUB SLC15A2 TLR4 PLCB3 NOTCH1	2.23e-04	215	117	6	DOID:9970 (implicated_via_orthology)
Disease	mitochondrial metabolism disease (implicated_via_orthology)	POLG LETM1 YME1L1	3.62e-04	35	117	3	DOID:700 (implicated_via_orthology)
Disease	common bile duct neoplasm (is_marker_for)	APOB MUC5AC	4.30e-04	8	117	2	DOID:4608 (is_marker_for)
Disease	melanoma	LRP1B SLC15A2 NFKBIE TLR4 STIP1 CCDC63	4.77e-04	248	117	6	C0025202
Disease	dry eye syndrome (is_marker_for)	TLR4 MUC5AC	6.87e-04	10	117	2	DOID:10140 (is_marker_for)
Disease	multiple sclerosis symptom measurement	STAB2 ITPRID1 SLC25A48	8.14e-04	46	117	3	EFO_0803536
Disease	developmental disorder of mental health (implicated_via_orthology)	NAA15 PLXNB2 NCOR2	9.80e-04	49	117	3	DOID:0060037 (implicated_via_orthology)
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	TLR4 PLCL1 FAM118A CLEC16A NOTCH1 DNPEP	1.17e-03	295	117	6	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	1.18e-03	13	117	2	DOID:3121 (is_implicated_in)
Disease	5-methyluridine (ribothymidine) measurement	NCAPH2 CPT1B	1.38e-03	14	117	2	EFO_0020013
Disease	Adenocarcinoma of lung (disorder)	PSAT1 LATS1 SATB1 SLC15A2 SOS1	1.41e-03	206	117	5	C0152013
Disease	Neoplasm of uncertain or unknown behavior of bladder	KDM6A NOTCH1	1.58e-03	15	117	2	C0496930
Disease	Benign neoplasm of bladder	KDM6A NOTCH1	1.58e-03	15	117	2	C0154017
Disease	Carcinoma in situ of bladder	KDM6A NOTCH1	1.58e-03	15	117	2	C0154091
Disease	otitis media (biomarker_via_orthology)	MUC5AC CTSL	2.04e-03	17	117	2	DOID:10754 (biomarker_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	TSNAXIP1 APOB NCOR2 PPP2R3A PLCB3	2.23e-03	229	117	5	EFO_0004639, EFO_0008317
Disease	Carcinoma of bladder	KDM6A NOTCH1	2.29e-03	18	117	2	C0699885
Disease	cerebral infarction (is_marker_for)	APOB SOS1	2.55e-03	19	117	2	DOID:3526 (is_marker_for)
Disease	intellectual disability (implicated_via_orthology)	NAA15 PSMB1 ITSN2	3.33e-03	75	117	3	DOID:1059 (implicated_via_orthology)
Disease	Kidney Failure	MYH9 TLR4	3.42e-03	22	117	2	C0035078
Disease	Sensorineural Hearing Loss (disorder)	MYH9 YME1L1	3.73e-03	23	117	2	C0018784

Protein segments in the cluster

Peptide	Gene	Start	Entry
QSPFNDLNRQLVNMG	FAM241B	61	Q96D05
LQRNINENFGPNTEM	DNPEP	181	Q9ULA0
KLEDKQPGNMAGNFN	CDCP1	296	Q9H5V8
PSKINLNMDQFLEQA	ABCA12	506	Q86UK0
QDPNINDNLLGNIMA	ANKIB1	961	Q9P2G1
LLVFANKQDLPNAMN	ARF3	121	P61204
FRGLKKEDNQNAMPF	ANGPTL5	286	Q86XS5
PKNNFAERQKRLQAM	CCDC74B	356	Q96LY2
RNAGQLDNFLLQQMP	CC2D2B	736	Q6DHV5
GMRPNAKNNRDLDFT	PRMT1	336	Q99873
GRDKNIPAGLQSMNQ	RABL6	16	Q3YEC7
LNERIKNMQFSNTPD	ITSN2	561	Q9NZM3
NNPFKQENVLARMVA	OFD1	591	O75665
NGDKARLENMSPRQV	KIAA1107	131	Q9UPP5
FLNMFANKQLELPRG	HECW2	976	Q9P2P5
APLENFNVKNIVNML	DAAM2	421	Q86T65
DADQQRIKFINMNGL	NCOR2	401	Q9Y618
EQMDFRANLQRQVKP	MYLK	921	Q15746
GANKDMQNNREETPL	NOTCH1	2051	P46531
PGFQRNMKNRQCEDL	LRP1B	3831	Q9NZR2
AQQMRFEPDNKNTQR	LYSMD3	191	Q7Z3D4
MDKQPANFIVLLNNV	MGAM2	856	Q2M2H8
AQKQRMDIENPNLYG	ITPRID1	186	Q6ZRS4
VNPQMLQDLQAAGFD	LATS1	101	O95835
QMLQAIRKANPGSDF	MTMR7	221	Q9Y216
NNNIKAIPEKAFMGN	LGR6	266	Q9HBX8
SAGQIDQNFKMPQEI	DYDC2	141	Q96IM9
KNQPLMELLLRNGAD	NFKBIE	381	O00221
DNPQLSALLMGKANN	KDM6A	776	O15550
QNNRDAMELKPNGGA	KCNH5	776	Q8NCM2
LEMDQQAGKLAPANG	LETM1	626	O95202
RNFINDEMQAKGIPQ	PCMTD1	256	Q96MG8
EDPAAQKMQLAFRLQ	PLXNB2	1811	O15031
FLQLRNLNDNQPMFE	FAT2	551	Q9NYQ8
LEQGKQQLMPQEAGL	POLG	661	P54098
RLIGDAAKNQVAMNP	HSPA1L	51	P34931
NTNGRLMANPEALKI	GBP1	16	P32455
NLQAMKAQFERDLQG	MYH9	1561	P35579
GLVCRNQDQQGPFKM	MUC5AC	1816	P98088
GLVCRNQDQQGPFKM	MUC5AC	4026	P98088
QNVFPAKEQFMVQRG	PLEKHM3	86	Q6ZWE6
KLPFEFMQSGNNEAL	PPP2R3A	291	Q06190
QEMNRLFGATNPKNF	NAA15	736	Q9BXJ9
LNAPTQFKGRLNELM	NUP54	421	Q7Z3B4
LNTMNFDLINGKPFR	PABPC5	76	Q96DU9
GDNPQRALDINKVML	MYO15B	506	Q96JP2
LMDFINQKQRDPRLN	PLCB3	246	Q01970
GNQPQNGRMLVSKDA	DTX3	211	Q8N9I9
NLLEAFGRRQNKPME	FAM118A	151	Q9NWS6
NSLKEFNLQNMGLPD	APOB	1256	P04114
SHQLQKAMPFLQNRG	ICE1	816	Q9Y2F5
QIFAKMQEANNPRKL	CCDC63	136	Q8NA47
LFIINNFANSDRPMK	DOCK11	1551	Q5JSL3
KEELMQDLQNPGGNR	CCDC122	166	Q5T0U0
PDFQLQAMIQAAGKL	CHD6	771	Q8TD26
NQNCLKNAGNPRDMR	EBF4	196	Q9BQW3
LLVFANKQDLPNAMN	ARF1	121	P84077
RLPMLDAKQLQNEND	CEP85L	596	Q5SZL2
MGNLNLPKPQQIDFA	ETHE1	226	O95571
NRNNQKPDRDGERNM	FSIP1	346	Q8NA03
MDKNLQGRLFISPAN	CCDC174	186	Q6PII3
LLFPENVMQNKDNAL	DDHD1	826	Q8NEL9
APFMKLAQQIQDGSR	DNAH2	316	Q9P225
EGFQDLLNMRPDQSN	SLC12A6	1066	Q9UHW9
NRNLGFFVLQPDQMQ	SLC15A2	331	Q16348
MQKNLQGLDPKALNN	SCARA3	101	Q6AZY7
FKNSEGKQLDPNEMR	SACS	3861	Q9NZJ4
ALKNRQNLFQEEGMI	RYR2	481	Q92736
EMKPNLDGVDLFNNG	CCDC102B	216	Q68D86
AMLQPLLDNQVGFKN	PSMB1	171	P20618
GARLLKPQDLEMQFQ	CPT1B	351	Q92523
QPLEVKNNSNLQRMG	CDC25A	61	P30304
GMEVNQPKFNQRRIS	UPF2	856	Q9HAU5
KLLLDFAAFPNQMEN	INVS	506	Q9Y283
NNPDFKAGVMALANL	RTRAF	126	Q9Y224
ALSQADVNLKMPRNN	ROGDI	81	Q9GZN7
KENNLNRLPKGMQAR	SPATA6L	171	Q8N4H0
EKQMIFFLNGNQLPP	RSPRY1	436	Q96DX4
PQLKEGLQNMEARLA	STIP1	106	P31948
DLLQSRGNFDPKAMN	TAB3	596	Q8N5C8
QELENQMKERQGLFF	TMEM120A	81	Q9BXJ8
NGALQPSDLDRNKMK	STK24	351	Q9Y6E0
QNRSKMNIPFRIGNA	PSAT1	296	Q9Y617
LQGAENNMSEIQKQP	SECISBP2	226	Q96T21
LQMQTQPFRDANLGL	SLC25A48	131	Q6ZT89
DIKRFFENLNPMGNS	SOS1	986	Q07889
EMEKGFNPAQPLNIR	NUP160	686	Q12769
GDFPNLKRMQDQLQA	EHD3	351	Q9NZN3
TERNGKPENNTMNIN	SATB1	481	Q01826
EEFRQVMNGFQNRKP	CTSL	86	P07711
DEMEKNNNPLYSRQG	NCAPH2	156	Q6IBW4
IMNNAAQPDGKIRLA	CLEC16A	546	Q2KHT3
KFDPQDMDKNLNAIQ	UNC45B	386	Q8IWX7
KQPLDFMEGNQNTPR	PLCL1	226	Q15111
GMDPLGNRERQNQKE	TEX13D	361	A0A0J9YY54
QNVKGETPLDMALQN	ZDHHC13	246	Q8IUH4
FPENLLGMQEAIQQA	RBP3	41	P10745
EPQMKVAALRAGAQQ	SECTM1	186	Q8WVN6
LQESNTPGLRQMNFK	SARG	466	Q9BW04
DKVELANMNRLFFQP	UBA5	106	Q9GZZ9
QENNDLALQPGDRIM	STAC2	306	Q6ZMT1
LARMENQAFDPEKGN	TRAM2	271	Q15035
NGPMLRLKANDFAQK	TIGD4	106	Q8IY51
FVPNNEALNNMKDGT	STAB2	556	Q8WWQ8
NFIDLMVRQGNIDNP	VAT1L	81	Q9HCJ6
LAMLEQPLGNEQNDF	RALGAPB	956	Q86X10
QGLQPNGEEMTLKQF	UBA1	961	P22314
GKNFNLNMNFVPLRK	ZNF84	111	P51523
KNLNMNRAPDNIIKF	YY1AP1	326	Q9H869
NQLLAEMDGFKPNEG	YME1L1	461	Q96TA2
ESQQENQRMGKGQIP	ZFP69B	196	Q9UJL9
NTGQPEKQGRNDMIQ	ZSWIM3	606	Q96MP5
GNFLQSLPAELENMK	PHLPP1	746	O60346
QDGESLQMFQALKRP	SUN1	736	O94901
NNMKANFGDVVPRRD	TSNAXIP1	246	Q2TAA8
SGAQMPNNIEKNFSR	XKRX	291	Q6PP77
LKMAGNSFQENFLPD	TLR4	476	O00206
KRQEPLMVQANADGR	TUB	41	P50607
EPKFNLMQILQDNGN	TTLL5	656	Q6EMB2
RNPMNALNVGKLLDI	ZNF487	256	B1APH4
ELPQFIQAKVNALNM	NEB	1521	P20929