Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesssynapse maturation

RELN ERBB4 NFATC4 ADGRL1

9.51e-0650554GO:0060074
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A1 CSNK2A3

4.06e-054552GO:0005956
DomainNFAT

NFATC1 NFATC4

8.16e-055542IPR008366
DomainRHD_dimer

NFATC1 NFATC4

3.64e-0410542IPR032397
DomainRHD_dimer

NFATC1 NFATC4

3.64e-0410542PF16179
DomainNFkB/Dor

NFATC1 NFATC4

3.64e-0410542IPR000451
DomainREL_1

NFATC1 NFATC4

3.64e-0410542PS01204
DomainRHD_DNA_bind_dom

NFATC1 NFATC4

3.64e-0410542IPR011539
DomainRHD_DNA_bind

NFATC1 NFATC4

3.64e-0410542PF00554
DomainREL_2

NFATC1 NFATC4

3.64e-0410542PS50254
Domain-

NFATC1 NFATC4

3.64e-04105422.60.40.340
Domainp53-like_TF_DNA-bd

NFATC1 NFATC4 TBX1

4.83e-0453543IPR008967
Domainfn3

EBI3 PTPRM MYOM3 CNTN2

1.23e-03162544PF00041
DomainFN3

EBI3 PTPRM MYOM3 CNTN2

2.00e-03185544SM00060
DomainNucleotide-diphossugar_trans

B3GALT1 UGP2 GALNT18

2.11e-0388543IPR029044
DomainFN3

EBI3 PTPRM MYOM3 CNTN2

2.61e-03199544PS50853
DomainIPT

NFATC1 NFATC4

2.75e-0327542SM00429
Domain-

NFATC1 EBI3 PTPRM NFATC4 CD226 MYOM3 CNTN2

2.86e-036635472.60.40.10
DomainFN3_dom

EBI3 PTPRM MYOM3 CNTN2

3.11e-03209544IPR003961
DomainTIG

NFATC1 NFATC4

3.62e-0331542PF01833
DomainIPT

NFATC1 NFATC4

3.85e-0332542IPR002909
DomainIg-like_fold

NFATC1 EBI3 PTPRM NFATC4 CD226 MYOM3 CNTN2

4.05e-03706547IPR013783
DomainEF-hand_8

CAPN11 MICU1

4.34e-0334542PF13833
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FAM120B NF1 MARK3 ANXA1 CSNK2A1 PABPC3 UGP2 KCNAB2 ADGRL1 DDX3Y ELP3 TFAM CNTN2

2.65e-071431551337142655
Pubmed

Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.

KCNA3 KCNAB2

2.46e-06255235091471
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A1 CSNK2A3

2.46e-06255214646071
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A1 CSNK2A3

2.46e-0625521577469
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A1 CSNK2A3

2.46e-06255212860116
Pubmed

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.

CD226 ITGB2

2.46e-06255225825444
Pubmed

Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes.

NFATC1 TFAM

2.46e-06255222709542
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A1 CSNK2A3

2.46e-0625522752008
Pubmed

Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells.

NFATC1 NFATC4

2.46e-06255228760926
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A1 CSNK2A3

2.46e-0625528420794
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

SETD1A GTF3C1 TRRAP

2.50e-061755321653943
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

SETD1A GTF3C1 TRRAP

3.00e-061855317846119
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

NF1 MARK3 CSNK2A1 PABPC3 KCNAB2 ADGRL1 ELP3

5.12e-0643055732581705
Pubmed

Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.

RELN ERBB4 CNTN2

6.48e-062355325875176
Pubmed

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

CSNK2A1 CSNK2A3

7.36e-06355215684395
Pubmed

CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation.

CD226 ITGB2

7.36e-06355214676297
Pubmed

Physical and functional association of LFA-1 with DNAM-1 adhesion molecule.

CD226 ITGB2

7.36e-06355210591186
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A1 CSNK2A3

7.36e-0635522174700
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A1 CSNK2A3

7.36e-0635521766873
Pubmed

Crystallization and preliminary characterization of crystals of human protein kinase CK2.

CSNK2A1 CSNK2A3

7.36e-06355211092945
Pubmed

Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

CSNK2A1 CSNK2A3

7.36e-06355212102635
Pubmed

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

CSNK2A1 CSNK2A3

7.36e-06355220625391
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH3 NF1 GTF3C1 NFATC4 MARK3 ANXA1 CSNK2A1 CSNK2A3 TRRAP

1.19e-0591055936736316
Pubmed

Alternative splicing and expression of human and mouse NFAT genes.

NFATC1 NFATC4

1.47e-05455218675896
Pubmed

Transcription factors of the NFAT family: regulation and function.

NFATC1 NFATC4

1.47e-0545529143705
Pubmed

Nuclear factor of activated T cells is activated in the endothelium of retinal microvessels in diabetic mice.

NFATC1 NFATC4

1.47e-05455225918731
Pubmed

Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro.

CD226 ITGB2

1.47e-05455225684021
Pubmed

NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis.

NFATC1 NFATC4

1.47e-05455226527057
Pubmed

HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.

NFATC1 NFATC4

1.47e-05455216260021
Pubmed

The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis.

NFATC1 NFATC4

1.47e-05455224970700
Pubmed

Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice.

RELN CNTN2

1.47e-05455216324103
Pubmed

Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process.

CD226 ITGB2

2.45e-05555216831868
Pubmed

Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.

NFATC1 NFATC4

2.45e-05555217693409
Pubmed

Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.

NFATC1 NFATC4

2.45e-05555222593154
Pubmed

Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons.

RELN CNTN2

2.45e-05555210399933
Pubmed

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1.

KCNAB2 CNTN2

2.45e-05555212963709
Pubmed

NFAT: ubiquitous regulator of cell differentiation and adaptation.

NFATC1 NFATC4

2.45e-05555211877454
Pubmed

Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif.

NFATC1 NFATC4

2.45e-0555527999066
Pubmed

Nf1 has an essential role in endothelial cells.

NF1 NFATC1

2.45e-05555212469121
Pubmed

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT.

NFATC1 NFATC4

2.45e-05555210089876
Pubmed

Subunit composition of Kv1 channels in human CNS.

KCNA3 KCNAB2

2.45e-05555210428084
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

ERBB4 ANXA1 CSNK2A1 PABPC3 DDX3Y

2.60e-0522055524550385
Pubmed

Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.

NFATC1 TFAM

3.67e-05655237891230
Pubmed

Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.

NFATC1 NFATC4

3.67e-05655224352425
Pubmed

A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.

NFATC1 NFATC4

3.67e-05655216141075
Pubmed

Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering.

NFATC1 NFATC4

3.67e-0565528814265
Pubmed

Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.

NFATC1 NFATC4

3.67e-05655221880741
Pubmed

Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.

NFATC1 NFATC4

3.67e-05655212788643
Pubmed

The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins.

NFATC1 NFATC4

3.67e-05655225728138
Pubmed

A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis.

NFATC1 NFATC4

3.67e-05655215339668
Pubmed

Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells.

NFATC1 NFATC4

3.67e-05655216690925
Pubmed

Migration of sympathetic preganglionic neurons in the spinal cord of a C3G-deficient mouse suggests that C3G acts in the reelin signaling pathway.

RELN CNTN2

3.67e-05655222351125
Pubmed

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

NFATC1 NFATC4

5.13e-05755216554754
Pubmed

Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells.

NFATC1 NFATC4

5.13e-05755218097055
Pubmed

NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

NFATC1 NFATC4

5.13e-05755218218901
Pubmed

Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

KCNAB2 CNTN2

5.13e-05755218509034
Pubmed

Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.

NFATC1 NFATC4

5.13e-05755217430895
Pubmed

Calcium/NFAT signalling promotes early nephrogenesis.

NFATC1 NFATC4

5.13e-05755221295565
Pubmed

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

CSNK2A1 CSNK2A3

5.13e-05755211239457
Pubmed

Genomic organization and genetic mapping of the neuroimmune gene I2rf5 to mouse chromosome 4.

KCNAB2 SKI

6.83e-0585527774930
Pubmed

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.

NFATC1 NFATC4

6.83e-05855212370307
Pubmed

Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity.

NFATC1 NFATC4

6.83e-0585527957556
Pubmed

Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations.

RELN ERBB4

6.83e-05855222376909
Pubmed

p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.

CSNK2A1 CSNK2A3

6.83e-05855212393879
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH3 GPR19 GTF3C1 PABPC3 UGP2 SPAG17 SKI TFAM TBX1 CAPN11

7.75e-051442551035575683
Pubmed

Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons.

RELN CNTN2

8.78e-05955231693895
Pubmed

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.

ERBB4 NF1 PTPRM

9.26e-055555332561725
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

ARID1B GTF3C1 CSNK2A1 CSNK2A3

9.55e-0515055428242625
Pubmed

Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling.

NFATC1 NFATC4

1.10e-041055219710169
Pubmed

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development.

RELN CNTN2

1.10e-041055216407979
Pubmed

The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes.

NFATC4 TFAM

1.10e-041055219653005
Pubmed

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.

MYH3 MYOM3 TFAM

1.26e-046155327166947
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

SNIP1 SETD1A ARID1B NF1 TRRAP TMC3 GALNT18 CAPN11 CYBA

1.33e-04124255930973865
Pubmed

Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.

NFATC1 NFATC4

1.34e-041155220824138
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

RELN CNTN2

1.34e-041155223968836
Pubmed

Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain.

RELN CNTN2

1.34e-041155220170731
Pubmed

Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules.

ERBB4 CNTN2

1.60e-041255215457507
Pubmed

ErbB4 in Laminated Brain Structures: A Neurodevelopmental Approach to Schizophrenia.

RELN ERBB4

1.60e-041255226733804
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

SETD1A ELP3 TRRAP

1.82e-046955328481362
Pubmed

Transcription factor ETV1 is essential for rapid conduction in the heart.

ERBB4 CNTN2

1.89e-041355227775552
Pubmed

Arabidopsis HY5 protein functions as a DNA-binding tag for purification and functional immobilization of proteins on agarose/DNA microplate.

MARK3 CSNK2A1

1.89e-041355218082144
Pubmed

NRIP is newly identified as a Z-disc protein, activating calmodulin signaling for skeletal muscle contraction and regeneration.

MYH3 NFATC1

1.89e-041355226430214
Pubmed

Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex.

RELN CNTN2

1.89e-041355212091317
Pubmed

Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells.

RELN CNTN2

1.89e-041355226525675
Pubmed

Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain.

RELN CNTN2

2.21e-041455222821687
Pubmed

Ablation of CNTN2+ Pyramidal Neurons During Development Results in Defects in Neocortical Size and Axonal Tract Formation.

RELN CNTN2

2.21e-041455231749685
Pubmed

Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.

RELN CNTN2

2.21e-041455215964824
Pubmed

Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development.

MYH3 SKI

2.21e-04145529284043
Pubmed

Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients.

NFATC1 NFATC4

2.54e-041555221047202
Pubmed

Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries.

NFATC1 TBX1

2.54e-041555223797856
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RELN FAM120B ARID1B GTF3C1 CSNK2A1 DDX3Y TRRAP TFAM

2.85e-04108255838697112
Pubmed

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons.

RELN ERBB4

2.90e-041655220713522
Pubmed

STAT5A/B activity is required in the developing forebrain and spinal cord.

RELN CNTN2

2.90e-041655217462911
Pubmed

Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis.

RELN CNTN2

2.90e-041655219948886
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

GTF3C1 NFATC1 NFATC4 CSNK2A1 SKI TFAM

3.12e-0458355629844126
Pubmed

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.

ERBB4 ANXA1 CNTN2

3.14e-048355320029029
Pubmed

Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.

RELN ERBB4

3.29e-041755217376983
Pubmed

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.

RELN CNTN2

3.70e-041855227320921
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

RELN CNTN2

3.70e-041855215570159
Pubmed

Human transcription factor protein interaction networks.

SETD1A ARID1B GTF3C1 NFATC4 CSNK2A1 PABPC3 SKI TRRAP TFAM

3.76e-04142955935140242
Cytoband11p15.3

CSNK2A3 GALNT18

2.92e-042155211p15.3
GeneFamilyNuclear factors of activated T-cells

NFATC1 NFATC4

3.42e-055342665
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

EBI3 SLC19A1 DDX3Y

1.19e-0451343870
GeneFamilyFibronectin type III domain containing

EBI3 PTPRM MYOM3 CNTN2

2.23e-04160344555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PTPRM MYOM3 CNTN2

3.39e-03161343593
GeneFamilyImmunoglobulin like domain containing

PTPRM MYOM3 CNTN2

5.62e-03193343594
GeneFamilyEF-hand domain containing

TBC1D8B CAPN11 MICU1

7.96e-03219343863
GeneFamilyG protein-coupled receptors, Class A orphans

GPR161 GPR19

9.43e-0378342262
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NFATC1 ANXA1 GALNT18 TBX1

3.59e-06192545ee9a23a4f00424a50bd7907cf3b12dc50027877e
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NFATC1 ANXA1 GALNT18 TBX1

3.87e-0619554536d4a11bc77a4cc97a22525c78ef8359f4a3ca66
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

CD226 MFHAS1 ANXA1 UGP2 SKI

3.87e-061955456687e579582d7a239bee80846de0cf827a6f6a62
ToppCellAdult-Immune-monocyte-D122|Adult / Lineage, Cell type, age group and donor

EBI3 KCNAB2 EMILIN2 ITGB2 CYBA

3.96e-0619654516b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell(0)_NK_cells-(0)_NK_FCGR3Apos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GTF3C1 CD226 ANXA1 ITGB2 CYBA

4.17e-06198545eba39656c6f699ab297b652ded8cb9727b49593c
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD226 ANXA1 KCNAB2 DDX3Y ITGB2

4.27e-06199545b01328a80db5bb088c44564cea0f6729b1a9805b
ToppCellCTRL-Myeloid|CTRL / Disease state, Lineage and Cell class

PTPRM KCNAB2 EMILIN2 ITGB2 CYBA

4.27e-0619954570b89a930709fdb91fde6f96106add8455b11618
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GPR161 RELN ERBB4 PTPRM

4.37e-06200545862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GPR161 RELN ERBB4 PTPRM

4.37e-06200545a91345f268f13170c27309333603eb82400c9947
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-dn_T|ICU-SEP / Disease, condition lineage and cell class

FAM120B CNNM2 GTF3C1 AGMAT TBX1

4.37e-062005459ee3e18dc429b9c472e3e366d9bfdbb150daa369
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GPR161 RELN ERBB4 PTPRM

4.37e-06200545d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 PTPRM TBC1D8B

1.56e-05124544690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 PTPRM TBC1D8B

1.88e-051305448bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 PTPRM TBC1D8B

1.88e-0513054460e28d452d0e2af768459ba8dbe998117c94a251
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR161 RELN PTPRM EMILIN2

2.81e-0514454471107275767a0728541a3695715c44874b3e5efc
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

MYH3 GPR19 EBI3 UGP2

2.89e-0514554429422c908d58081e6a748e362a7ac41bf001444c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR161 RELN PTPRM EMILIN2

3.05e-0514754450e86860a94be103092c40e39a172eac92372f0d
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 ANXA1 ITGB2 CYBA

3.13e-0514854474f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EBI3 CD226 EMILIN2 ITGB2

3.21e-0514954443d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EBI3 CD226 EMILIN2 ITGB2

3.21e-051495441c5a2572741c47246d455c865e8e1677c9f49598
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 ANXA1 ITGB2 CYBA

3.21e-051495444de52569611e63a780cde9bd111d6d9c11a05a11
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 ANXA1 ITGB2 CYBA

3.21e-05149544c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCellImmune_cells-Neutrophils|World / Lineage and Cell class

EBI3 ANXA1 ITGB2 CYBA

3.38e-05151544056301bedb4285e797250b55d79ee1790a17516d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 PTPRM TBC1D8B

3.47e-051525448ff5a178a8f3550d89a003c0858820aab3773386
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

3.94e-05157544857cd7edc872ade3f0164abefe61600c69d16f58
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

4.04e-05158544097a1b719da5c99a7db8531ab45913bd9270b497
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

4.14e-05159544dd9059f98eec43adbcc0cd42bb155670f7a3a479
ToppCellE17.5-Hematopoietic|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EBI3 EMILIN2 ITGB2 CYBA

4.14e-05159544a5648f731f1a22d1af1be2b0e1b80e29d05bae04
ToppCellBac-SEP-Lymphocyte-T_NK-dnT|Bac-SEP / Disease, Lineage and Cell Type

KCNA3 NFATC1 LRRC56 AGMAT

4.24e-05160544f5ca49801c981b903a85a64b21ece6b59fe91cbc
ToppCellE17.5-Hematopoietic-Immune-immune_cell_unspecified|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EBI3 EMILIN2 ITGB2 CYBA

4.35e-0516154430741ca6548db2dfb5cf1faecf0d7412c91d0077
ToppCellE17.5-Hematopoietic-Immune|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EBI3 EMILIN2 ITGB2 CYBA

4.35e-05161544e3ff08d0b9c686253556c56ee88648206751ef2b
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

4.56e-0516354445a0a03d642a9751f522b2f068598ab5de4a87bd
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

4.78e-051655441d844d19ff9b49dd0f61f0b24799e172076771ef
ToppCellPND14-Immune-Immune_Myeloid|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

4.78e-05165544e37d00084f58fbd25f66ee65be510c030167084e
ToppCellE18.5-Immune-Immune_Myeloid|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

4.78e-0516554457de10d9237e56fafaa58995792f998fecc77e7a
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

4.78e-051655449a6abd0e6b11860231ce5e845c87b8d66f3ef697
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA1 MYOM3 KCNAB2 EMILIN2

4.78e-05165544ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

4.78e-05165544433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

4.89e-0516654473b472ea846968a08b2ac09269fca5b333ecdf2d
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNA3 GTF3C1 KCNAB2 ITGB2

4.89e-05166544e4f14b2dd8c6199fa27cc3e3beeda681a3b5b889
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM5 ANXA1 CNTN2 CAPN11

4.89e-05166544c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCellPND28-Immune-Immune_Myeloid|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

4.89e-05166544caa992944bc7488a6868dbd1902bc3ead6945eb1
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

FAM120B CNNM2 GTF3C1 TBX1

4.89e-0516654496d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellE18.5-Immune|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

5.01e-051675440878ea803621a139c91016a7fb49b59ccc502c1a
ToppCellImmune_cells-Neutrophils|Immune_cells / Lineage and Cell class

EBI3 ANXA1 ITGB2 CYBA

5.13e-051685443539f802fe0143da1462df0618f78f9f15143f71
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

RELN ERBB4 KCNA3 PTPRM

5.25e-05169544c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCellE16.5-Immune-Immune_Myeloid|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

5.37e-05170544a249696c6aae08e83f44b263fc838582a2736ee5
ToppCellE16.5-Immune|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 EMILIN2 ITGB2 CYBA

5.49e-05171544b5916748fa0cecc887527be645df88a9ebd0a822
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

5.62e-05172544e72966ced5f2ee9e24ce9fd820d99a69a482a607
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NF1 MFHAS1 UGP2 TMC3

5.62e-05172544eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANXA1 EMILIN2 ITGB2 CYBA

5.62e-0517254483730ea3b240b8e2f2a9fb6c34dd1408050867ff
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

ERBB4 ANXA1 ITGB2 CYBA

5.75e-051735441e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 CD226 KCNAB2 ITGB2

6.28e-0517754431201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 CD226 KCNAB2 ITGB2

6.28e-0517754489d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_large-bowel / Manually curated celltypes from each tissue

MYH3 KCNA3 PTPRM ANXA1

6.56e-051795446359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA1 EMILIN2 ITGB2 CYBA

6.56e-051795446d2458a887047b5c20389f08345ff5aac7c683e6
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNA3 CD226 MFHAS1 TBX1

6.56e-051795446bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNA3 CD226 MFHAS1 ANXA1

6.70e-05180544d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD226 ANXA1 KCNAB2 ITGB2

7.00e-051825447dd435e456da1470d19d3db307ae4909c25d2f0d
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

CD226 KCNAB2 ITGB2 CYBA

7.00e-05182544257a7847917b6ea1d60608183d90300bfd028758
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

GTF3C1 CD226 ITGB2 CYBA

7.00e-0518254452baef8173df0a55307c375674a37c2488066738
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

RELN ERBB4 KCNA3 PTPRM

7.00e-05182544b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT1 RELN ERBB4 PTPRM

7.45e-0518554479cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 CD226 KCNAB2 ITGB2

7.61e-051865446e3bea4319d2a1bb060fe0cb1bb8bafafa05f83c
ToppCelldroplet-Marrow-nan-18m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA1 UGP2 ITGB2 CYBA

7.93e-05188544fa7a612b0a2b35de5f76a0408168dabe5db00773
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NFATC1 MFHAS1 ANXA1 SKI

8.10e-05189544284f39dfacec76004daae9dd5317fb7b1f04fa99
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA1 UGP2 EMILIN2 DDX3Y

8.10e-051895446e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFATC1 PABPC3 DDX3Y CYBA

8.26e-051905444d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GTF3C1 ANXA1 DDX3Y ITGB2

8.43e-05191544b2d0ea24970da09209da9d9dda76e30fbfe22917
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR161 RELN ERBB4 PTPRM

8.43e-051915447b386512284dfaa0e95358b28ee82632ee965e64
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RELN NFATC1 UGP2 TBX1

8.43e-05191544d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCellBLOOD--(1)_gd_T_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 CD226 ANXA1 ITGB2

8.43e-0519154447ced00ed6fb47ddc6e9baa76186ea974720defd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT1 RELN ERBB4 PTPRM

8.43e-05191544fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellBLOOD--(1)_T_cell-(1)_gd_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 ANXA1 ITGB2 CYBA

8.43e-05191544c6914e2733de20ecd6d1d27786b9a03992d612e7
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

RELN P3H2 GALNT18 TBX1

8.60e-051925442496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 PTPRM GALNT18

8.60e-05192544bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNA3 NFATC1 ANXA1 DDX3Y

8.60e-051925443e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 KCNA3 PTPRM

8.60e-0519254467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

ANXA1 DDX3Y ITGB2 CYBA

8.60e-0519254482e6a818b6c56a1556d2a1aea2e56676369556df
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 KCNA3 PTPRM

8.78e-051935449f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 PTPRM GALNT18

8.78e-05193544294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFATC1 MFHAS1 GALNT18 TBX1

8.78e-05193544eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MFHAS1 P3H2 GALNT18

8.78e-05193544263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MFHAS1 P3H2 GALNT18

8.78e-0519354480e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MFHAS1 P3H2 GALNT18

8.78e-05193544b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 PTPRM GALNT18

8.78e-051935443d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN KCNA3 PTPRM EMILIN2

8.78e-05193544e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

GTF3C1 ANXA1 ITGB2 CYBA

8.78e-051935443184a5f454e3ac5a81f6bacf9bd8f07d9d448fba
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN KCNA3 PTPRM EMILIN2

8.78e-05193544658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+|normal / PBMC cell types (v2) per disease, treatment status, and sex

GTF3C1 ANXA1 ITGB2 CYBA

8.78e-05193544123d4d13c8944c32bf4a5d7fdc65e3b65aa568ef
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MFHAS1 P3H2 GALNT18

8.95e-05194544e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellBLOOD--(1)_EM_CTLs| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 ANXA1 ITGB2 CYBA

8.95e-0519454466583c6cff3814902d6babdea3a2ae962decde65
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

KCNA3 PTPRM MFHAS1 ANXA1

8.95e-051945444547b57669be5d4f0de55175802ee04372288a6a
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFATC1 MFHAS1 GALNT18 TBX1

8.95e-051945445d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 KCNA3 PTPRM

8.95e-051945444f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ERBB4 KCNA3 PTPRM

8.95e-0519454402a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCellBLOOD--(1)_T_cell-(1)_EM_CTLs|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GTF3C1 ANXA1 ITGB2 CYBA

9.13e-051955447df67ad5c62235474ee56ea07a957253d45f066b
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

ANXA1 EMILIN2 DDX3Y ITGB2

9.13e-051955440fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PTPRM GALNT18 TBX1

9.13e-051955447f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

RELN PTPRM GALNT18 TBX1

9.13e-05195544094cf6591daa5ffad36e44122b6f524a3a34c2fd
DrugICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A

GPR161 SETD1A NF1 NFATC1 P3H2 TBX1

6.84e-061925564462_DN
DrugTropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A

RELN NF1 KCNAB2 ADGRL1 SKI TBX1

8.39e-061995563569_UP
DiseaseChromosome 1p36 Deletion Syndrome

KCNAB2 SKI

3.15e-055532C1842870
DiseaseCutaneous Melanoma

ERBB4 NF1 TRRAP

5.56e-0541533C0151779
Diseaserisk-taking behaviour

RELN FAM120B ARID1B NF1 PTPRM MFHAS1 MARK3 CNTN2

6.16e-05764538EFO_0008579
Diseaseschizophrenia (implicated_via_orthology)

SETD1A RELN CNNM2

2.52e-0468533DOID:5419 (implicated_via_orthology)
Diseaseventricular septal defect (is_implicated_in)

NFATC1 TBX1

2.84e-0414532DOID:1657 (is_implicated_in)
Diseaseotosclerosis

RELN MFHAS1 MARK3

4.23e-0481533EFO_0004213
Diseaseischemia (biomarker_via_orthology)

ARID1B ANXA1

4.75e-0418532DOID:326 (biomarker_via_orthology)
Diseasesystemic lupus erythematosus

ERBB4 GPR19 NFATC1 CD226 MFHAS1 LRRC56 ELP3

5.42e-04799537MONDO_0007915
DiseaseSeizures

CNNM2 CSNK2A1 UGP2 TRRAP

6.39e-04218534C0036572
Diseaseuric acid measurement

ERBB4 CNNM2 NFATC1 AGMAT SKI TFAM

7.67e-04610536EFO_0004761
Diseasemalignant astrocytoma (is_marker_for)

NF1 ANXA1

7.82e-0423532DOID:3069 (is_marker_for)
Diseasecongenital heart disease (is_implicated_in)

NFATC1 TBX1

8.52e-0424532DOID:1682 (is_implicated_in)
Diseasesupramarginal gyrus volume measurement

ERBB4 MFHAS1

8.52e-0424532EFO_0010332
Diseasecomparative body size at age 10, self-reported

RELN NF1 NFATC1 MFHAS1 ELP3

9.34e-04420535EFO_0009819
DiseaseEpilepsy

SETD1A ARID1B KCNAB2

1.00e-03109533C0014544
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

NF1 ADGRL1

1.16e-0328532DOID:1094 (implicated_via_orthology)
DiseaseDevelopmental Academic Disorder

NF1 MICU1

1.25e-0329532C1330966
DiseaseLearning Disorders

NF1 MICU1

1.25e-0329532C0023186
DiseaseLearning Disturbance

NF1 MICU1

1.25e-0329532C0751263
DiseaseAdult Learning Disorders

NF1 MICU1

1.25e-0329532C0751262
DiseaseLearning Disabilities

NF1 MICU1

1.25e-0329532C0751265
DiseaseAutistic Disorder

RELN NF1 SLC19A1 TRRAP

1.25e-03261534C0004352
DiseaseHirschsprung Disease

RELN ARID1B

1.42e-0331532C0019569
DiseaseColorectal Carcinoma

NF1 NFATC1 CD226 SLC19A1 SPAG17 TBX1

1.58e-03702536C0009402

Protein segments in the cluster

PeptideGeneStartEntry
YFYKQNGRIRPIVAE

ERBB4

1266

Q15303
LVARNPLQGYYQVRR

ADGRL1

1431

O94910
KPTLYSIYNANFRRG

GPR19

326

Q15760
TKPRRRYFTGYVING

B3GALT1

196

Q9Y5Z6
FYATLVRYVGDRKNP

ARID1B

2181

Q8NFD5
YRVVPRGQSFKKNYA

CAPN11

156

Q9UMQ6
TTRSYPQLRRVFQKY

ANXA1

226

P04083
IFAYRGKVPVVVSYR

MFHAS1

916

Q9Y4C4
VVKLFGPFTRNYYVR

CYBA

76

P13498
NRIRAYSTPDKIFRY

MICU1

116

Q9BPX6
GKRKRSQYQRFTYLP

NFATC1

681

O95644
YYYQSGGRIRRPVNV

KCNA3

161

P22001
VRSDFQRRVPYNYLQ

P3H2

141

Q8IVL5
STRYGSPKRQLQFYR

KCNAB2

26

Q13303
RTVPRYKYAAGVRNP

PABPC3

501

Q9H361
SLVGNPVRFRFYQKY

RELN

2826

P78509
NVTFRRAKGYPIDLY

ITGB2

116

P05107
QEYNVRVASRYFKGP

CSNK2A3

186

Q8NEV1
LYIQAKYQRLRFTGP

BCLAF3

671

A2AJT9
RAVRPRARYYVQVAA

EBI3

191

Q14213
SPEGRRVALKQFQYY

GALNT18

106

Q6P9A2
YTPFEVKIRSYNRRG

CNTN2

781

Q02246
QEYNVRVASRYFKGP

CSNK2A1

186

P68400
TRNYYRKIGYRLQGP

ELP3

526

Q9H9T3
FIKRLPTEYERNGRY

MARK3

621

P27448
GDRYYREPFVQRQRT

GPR161

341

Q8N6U8
KSNQVRGLYDFYLPR

KLHDC2

51

Q9Y2U9
VYRVNFRPRYVTRYK

EMILIN2

86

Q9BXX0
IYVNYPTFSRRPKTR

CD226

321

Q15762
AVKENGRYGRRKQYP

DDX3Y

251

O15523
DKTRQTIPRIRNYYF

FAM111B

336

Q6SJ93
PSQAFIYRPIRQRVY

FAM120B

616

Q96EK7
RIFRIYNAARPQDGY

PTPRM

1326

P28827
AQKRRPGVYTKVYNY

PRSS3P2

221

Q8NHM4
GTFLNNKRIEPQRYY

SNIP1

336

Q8TAD8
YPRNVRQYASRVPRQ

TMC3

921

Q7Z5M5
TNKVPRGYNYRAEVR

LRRC56

206

Q8IYG6
RGYNYRAEVRKLIPQ

LRRC56

211

Q8IYG6
KRVSRPVQVYFYVSN

NFATC4

656

Q14934
PVQVYFYVSNGRRKR

NFATC4

661

Q14934
LDPYRYNRSQGFRVV

AGMAT

231

Q9BSE5
PNRILYGDFKQRYRV

MYH3

711

P11055
KRPRSAYNVYVAERF

TFAM

156

Q00059
ALRRPSQKVYRYDGV

SETD1A

31

O15047
FDYGNKYKRRVPRVS

SKI

311

P12755
IYYPFQKREQLRAGR

SPAG17

1556

Q6Q759
YAKRIEPVRRQGNYL

CNNM2

301

Q9H8M5
CRVKIYTFNQSRYPR

UGP2

181

Q16851
FRRVLYRPYLQIFGQ

TRPM5

906

Q9NZQ8
RRVLTAYAYRNPKIG

TBC1D8B

556

Q0IIM8
FSLVRPARYQRVAGY

SLC19A1

141

P41440
AGNPIFYYVARRFKT

NF1

1601

P21359
RYQPRFHVVYVDPRK

TBX1

236

O43435
VGRRARYIVKNPQAY

GTF3C1

1316

Q12789
QVGRVYPQAVYFPIR

TRRAP

3256

Q9Y4A5
GFYNPVTRVVKDYRN

MORN5

126

Q5VZ52
PRLFRAGKYRITNNY

MYOM3

196

Q5VTT5