Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	endoplasmic reticulum organization	GAK MIA3 RETREG2 RTN3 ZBED3 SEC16A	1.28e-05	107	99	6	GO:0007029
GeneOntologyCellularComponent	collagen trimer	COL3A1 COL4A3 FCN3 COLQ SFTPA2 SFTPA1	4.07e-06	88	100	6	GO:0005581
HumanPheno	Pulmonary opacity	COL3A1 SFTPA2 CSF2RB SFTPA1	1.97e-05	26	33	4	HP:0031457
HumanPheno	Pulmonary interstitial high-resolution computed tomography abnormality	COL3A1 SFTPA2 CSF2RB SFTPA1	2.68e-05	28	33	4	HP:0025389
Domain	Collagen	COL3A1 COL4A3 FCN3 COLQ SFTPA2 SFTPA1	5.27e-06	85	97	6	IPR008160
Domain	Collagen	COL3A1 COL4A3 FCN3 COLQ SFTPA2 SFTPA1	5.27e-06	85	97	6	PF01391
Domain	DH_1	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40	1.89e-05	63	97	5	PS00741
Domain	RhoGEF	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40	3.16e-05	70	97	5	PF00621
Domain	DH_2	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40	3.16e-05	70	97	5	PS50010
Domain	DH-domain	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40	3.38e-05	71	97	5	IPR000219
Domain	-	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40	3.38e-05	71	97	5	1.20.900.10
Domain	Notch	NOTCH3 NOTCH4	1.59e-04	4	97	2	IPR008297
Domain	NODP	NOTCH3 NOTCH4	1.59e-04	4	97	2	PF07684
Domain	Notch_NODP_dom	NOTCH3 NOTCH4	1.59e-04	4	97	2	IPR011656
Domain	Notch_NOD_dom	NOTCH3 NOTCH4	1.59e-04	4	97	2	IPR010660
Domain	NOD	NOTCH3 NOTCH4	1.59e-04	4	97	2	PF06816
Domain	NOD	NOTCH3 NOTCH4	1.59e-04	4	97	2	SM01338
Domain	NODP	NOTCH3 NOTCH4	1.59e-04	4	97	2	SM01339
Domain	LNR	NOTCH3 NOTCH4	2.64e-04	5	97	2	PS50258
Domain	hEGF	DLL3 NOTCH3 NOTCH4	4.05e-04	28	97	3	PF12661
Domain	RhoGEF	OBSCN ARHGEF25 ARHGEF17 PLEKHG5	4.32e-04	68	97	4	SM00325
Domain	Notch_dom	NOTCH3 NOTCH4	5.51e-04	7	97	2	IPR000800
Domain	Notch	NOTCH3 NOTCH4	5.51e-04	7	97	2	PF00066
Domain	Reticulon	RETREG2 RTN3	5.51e-04	7	97	2	PF02453
Domain	NL	NOTCH3 NOTCH4	5.51e-04	7	97	2	SM00004
Domain	Reticulon	RETREG2 RTN3	7.32e-04	8	97	2	IPR003388
Domain	Homeobox_metazoa	HMX2 HOXA4 HOXA10 HOXC12	1.24e-03	90	97	4	IPR020479
Domain	CTDL_fold	COL4A3 CD93 SFTPA2 SFTPA1	2.34e-03	107	97	4	IPR016187
Domain	Homeobox_CS	ALX3 HMX2 HOXA4 HOXA10 HOXC12	2.86e-03	186	97	5	IPR017970
Domain	EGF_CA	CD93 DLL3 NOTCH3 NOTCH4	3.76e-03	122	97	4	SM00179
Domain	EGF-like_Ca-bd_dom	CD93 DLL3 NOTCH3 NOTCH4	3.99e-03	124	97	4	IPR001881
Domain	EGF	CD93 DLL3 NOTCH3 NOTCH4	4.22e-03	126	97	4	PF00008
Domain	-	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 RGS12 ARHGEF40 AGAP2	4.27e-03	391	97	7	2.30.29.30
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL3 HES1 NOTCH3 NOTCH4	3.64e-07	13	69	4	M47423
Pathway	WP_NOTCH_SIGNALING_WP268	PTCRA DLL3 HES1 NOTCH3 NOTCH4	2.55e-06	45	69	5	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	PTCRA DLL3 HES1 NOTCH3 NOTCH4	2.84e-06	46	69	5	MM15971
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	PTCRA DLL3 HES1 NOTCH3 NOTCH4	3.17e-06	47	69	5	M7946
Pathway	REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5	SFTPA2 CSF2RB SFTPA1	6.18e-06	8	69	3	M27575
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	DLL3 HES1 NOTCH3 NOTCH4	8.47e-06	27	69	4	M39545
Pathway	WP_NOTCH_SIGNALING_WP61	PTCRA DLL3 HES1 NOTCH3 NOTCH4	1.17e-05	61	69	5	M39540
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM	SFTPA2 CSF2RB SFTPA1	1.31e-05	10	69	3	M27573
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380	HES1 NOTCH3 NOTCH4	2.39e-05	12	69	3	M47532
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381	HES1 NOTCH3 NOTCH4	2.39e-05	12	69	3	M47533
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382	HES1 NOTCH3 NOTCH4	3.10e-05	13	69	3	M47534
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	DLL3 HES1 NOTCH4	6.00e-05	16	69	3	M47424
Pathway	REACTOME_RHOA_GTPASE_CYCLE	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 ARHGEF40 DIAPH1	8.73e-05	149	69	6	M41805
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	OBSCN ARHGEF25 ARHGEF17 PLEKHG5	1.19e-04	52	69	4	MM14743
Pathway	PID_NOTCH_PATHWAY	PTCRA DLL3 NOTCH3 NOTCH4	1.95e-04	59	69	4	M17
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	OBSCN ARHGEF17 PLEKHG5 ARHGEF40	1.95e-04	59	69	4	M11215
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH3 NOTCH4	2.34e-04	5	69	2	M27411
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	NOTCH3 NOTCH4	2.34e-04	5	69	2	MM14733
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	PTCRA HES1 NOTCH3	2.39e-04	25	69	3	M27880
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH3 NOTCH4	3.50e-04	6	69	2	M27068
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	OBSCN ARHGEF25 ARHGEF17 PLEKHG5	3.78e-04	70	69	4	MM14824
Pathway	REACTOME_SURFACTANT_METABOLISM	SFTPA2 CSF2RB SFTPA1	4.14e-04	30	69	3	M27566
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ARHGEF25 ARHGEF17 ARHGEF40 DIAPH1	4.67e-04	74	69	4	M41807
Pathway	REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	NOTCH3 NOTCH4	4.88e-04	7	69	2	MM14734
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	OBSCN ARHGEF17 PLEKHG5 ARHGEF40	5.17e-04	76	69	4	M19832
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	OBSCN ARHGEF25 ARHGEF17 PLEKHG5	5.44e-04	77	69	4	MM15044
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	OBSCN ARHGEF17 PLEKHG5 ARHGEF40	6.28e-04	80	69	4	M800
Pathway	REACTOME_RHOA_GTPASE_CYCLE	OBSCN ARHGEF25 ARHGEF17 PLEKHG5 DIAPH1	6.47e-04	142	69	5	MM15576
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	OBSCN ARHGEF25 ARHGEF17 PLEKHG5	7.90e-04	85	69	4	MM14746
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION	NOTCH3 NOTCH4	1.26e-03	11	69	2	M47865
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	DLL3 HES1 NOTCH3 NOTCH4	1.29e-03	97	69	4	MM15926
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	OBSCN ARHGEF17 PLEKHG5 ARHGEF40	1.29e-03	97	69	4	M9400
Pathway	REACTOME_DISEASES_OF_METABOLISM	SFTPA2 CSF2RB ADAMTS15 SFTPA1 NOTCH3 NOTCH4	1.38e-03	250	69	6	M27554
Pathway	PID_RHOA_REG_PATHWAY	OBSCN ARHGEF25 ARHGEF17	1.47e-03	46	69	3	M68
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	DLL3 HES1 NOTCH3 NOTCH4	1.50e-03	101	69	4	M39448
Pathway	REACTOME_SIGNALING_BY_NOTCH3	PTCRA HES1 NOTCH3	1.76e-03	49	69	3	M618
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL3A1 COL4A3 LOXL3	1.87e-03	50	69	3	MM14796
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	SFTPA2 SFTPA1	2.07e-03	14	69	2	MM15011
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	HES1 NEUROG3	2.71e-03	16	69	2	M27121
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	SFTPA2 SFTPA1	2.71e-03	16	69	2	M925
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 OBSCN PER1 DGKQ ATG2A FHIP1B ZBED3 PLEKHG5 PPP1R26 ZCCHC14 MST1R GAS2L1 SCAF1 ARHGEF40 ARVCF SEC16A STRN4 LRP3 WDR90 CABIN1	6.54e-11	1105	102	20	35748872
Pubmed	Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.	COL3A1 DLL3 HES1 NOTCH3 NOTCH4 FOXD1	6.09e-09	48	102	6	35247391
Pubmed	Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.	DLL3 HES1 NOTCH3 NOTCH4	6.82e-08	14	102	4	14757642
Pubmed	Expression of Notch pathway components in fetal and adult mouse small intestine.	DLL3 HES1 NOTCH3 NOTCH4	1.24e-07	16	102	4	12617809
Pubmed	Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.	DLL3 HES1 NOTCH3 NOTCH4	1.24e-07	16	102	4	11739954
Pubmed	Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.	DLL3 HES1 NOTCH3 NOTCH4	1.61e-07	17	102	4	18694942
Pubmed	Segmental expression of Notch and Hairy genes in nephrogenesis.	DLL3 HES1 NOTCH3 NOTCH4	1.61e-07	17	102	4	15821257
Pubmed	Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.	DLL3 HES1 NOTCH3 NOTCH4	1.61e-07	17	102	4	39315665
Pubmed	RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.	DLL3 HES1 NOTCH3 NOTCH4	2.07e-07	18	102	4	15689374
Pubmed	Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.	DLL3 HES1 NOTCH3 NOTCH4	4.02e-07	21	102	4	28656980
Pubmed	Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.	HES1 NEUROG3 NOTCH3 NOTCH4	4.02e-07	21	102	4	14702043
Pubmed	A study on Notch signaling in human breast cancer.	HES1 NOTCH3 NOTCH4	4.87e-07	6	102	3	17822320
Pubmed	Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.	HES1 NOTCH3 NOTCH4	4.87e-07	6	102	3	15019995
Pubmed	Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.	HES1 NOTCH3 NOTCH4	4.87e-07	6	102	3	21991352
Pubmed	The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.	HES1 NEUROG3 NOTCH3 NOTCH4	8.41e-07	25	102	4	21786021
Pubmed	Cdc42-mediated tubulogenesis controls cell specification.	HES1 NEUROG3 NOTCH3 NOTCH4	1.35e-06	28	102	4	19914171
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	DLL3 HES1 NOTCH3 NOTCH4	1.57e-06	29	102	4	21402740
Pubmed	Notch signaling regulates ovarian follicle formation and coordinates follicular growth.	DLL3 HES1 NOTCH3 NOTCH4	1.80e-06	30	102	4	24552588
Pubmed	pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.	DLL3 HES1 NEUROG3 NOTCH3	1.80e-06	30	102	4	17257418
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	DLL3 NOTCH3 NOTCH4	2.03e-06	9	102	3	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	DLL3 NOTCH3 NOTCH4	2.03e-06	9	102	3	16245338
Pubmed	Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.	HES1 NOTCH3 NOTCH4	2.03e-06	9	102	3	12370315
Pubmed	A census of human transcription factors: function, expression and evolution.	ALX3 FOXN1 IRF7 DBP HMX2 ZBED3 HOXA4 HOXC12 NFATC3 SETBP1 DMRTA1 HES1 NEUROG3	2.64e-06	908	102	13	19274049
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	DLL3 NOTCH3 NOTCH4	2.90e-06	10	102	3	23665443
Pubmed	Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.	HES1 NOTCH3 NOTCH4	2.90e-06	10	102	3	14766969
Pubmed	Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.	DLL3 HES1 NOTCH3 NOTCH4	3.02e-06	34	102	4	17015435
Pubmed	Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.	DLL3 HES1 NOTCH3 NOTCH4	3.02e-06	34	102	4	21311046
Pubmed	Control of endodermal endocrine development by Hes-1.	DLL3 HES1 NEUROG3 NOTCH3	3.02e-06	34	102	4	10615124
Pubmed	Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.	DLL3 NOTCH3 NOTCH4	3.97e-06	11	102	3	10878608
Pubmed	Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.	HES1 NOTCH3 NOTCH4	3.97e-06	11	102	3	12866128
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ALX3 IRF7 DBP HMX2 HOXA4 HOXA10 HOXC12 NFATC3 DMRTA1 HES1	4.75e-06	544	102	10	28473536
Pubmed	Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.	HES1 NOTCH3 NOTCH4	5.29e-06	12	102	3	10952889
Pubmed	Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.	DLL3 NOTCH3 NOTCH4	5.29e-06	12	102	3	15465494
Pubmed	Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.	DLL3 HES1 NOTCH3	5.29e-06	12	102	3	14732396
Pubmed	Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos.	HOXA4 SFTPA2 SFTPA1	5.29e-06	12	102	3	10208743
Pubmed	Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.	COLQ DLL3 HES1 NOTCH3 NOTCH4	5.67e-06	86	102	5	35103284
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	DLL3 HES1 NOTCH3 NOTCH4	6.50e-06	41	102	4	22675208
Pubmed	Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.	DLL3 NOTCH3 NOTCH4	6.86e-06	13	102	3	11578869
Pubmed	Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome.	SFTPA2 SFTPA1	8.52e-06	2	102	2	31354704
Pubmed	Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.	SFTPA2 SFTPA1	8.52e-06	2	102	2	35444643
Pubmed	Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo.	SFTPA2 SFTPA1	8.52e-06	2	102	2	10749762
Pubmed	The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.	SFTPA2 SFTPA1	8.52e-06	2	102	2	17593964
Pubmed	Studies of the structure of lung surfactant protein SP-A.	SFTPA2 SFTPA1	8.52e-06	2	102	2	2610270
Pubmed	Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.	SFTPA2 SFTPA1	8.52e-06	2	102	2	9922219
Pubmed	Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24858142
Pubmed	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	SFTPA2 SFTPA1	8.52e-06	2	102	2	11867335
Pubmed	Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19228388
Pubmed	SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19494306
Pubmed	An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24793167
Pubmed	Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24954098
Pubmed	Characterization of a second human pulmonary surfactant-associated protein SP-A gene.	SFTPA2 SFTPA1	8.52e-06	2	102	2	1372511
Pubmed	Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation.	SFTPA2 SFTPA1	8.52e-06	2	102	2	21257967
Pubmed	The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.	SFTPA2 SFTPA1	8.52e-06	2	102	2	21205009
Pubmed	Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.	SFTPA2 SFTPA1	8.52e-06	2	102	2	38964703
Pubmed	Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.	SFTPA2 SFTPA1	8.52e-06	2	102	2	34917085
Pubmed	Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.	SFTPA2 SFTPA1	8.52e-06	2	102	2	22219327
Pubmed	ASXL1 and SETBP1 mutations and their prognostic contribution in chronic myelomonocytic leukemia: a two-center study of 466 patients.	ASXL1 SETBP1	8.52e-06	2	102	2	24695057
Pubmed	Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.	SFTPA2 SFTPA1	8.52e-06	2	102	2	15890661
Pubmed	Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.	SFTPA2 SFTPA1	8.52e-06	2	102	2	15385504
Pubmed	A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.	SFTPA2 SFTPA1	8.52e-06	2	102	2	23475791
Pubmed	Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.	NOTCH3 NOTCH4	8.52e-06	2	102	2	33665264
Pubmed	Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.	SFTPA2 SFTPA1	8.52e-06	2	102	2	23038062
Pubmed	Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24312669
Pubmed	Correlation analysis between single nucleotide polymorphisms of pulmonary surfactant protein A gene and pulmonary tuberculosis in the Han population in China.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24984162
Pubmed	Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.	SFTPA2 SFTPA1	8.52e-06	2	102	2	17580966
Pubmed	Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.	SFTPA2 SFTPA1	8.52e-06	2	102	2	3755136
Pubmed	Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.	SFTPA2 SFTPA1	8.52e-06	2	102	2	29394894
Pubmed	Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs.	SFTPA2 SFTPA1	8.52e-06	2	102	2	22384248
Pubmed	The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration.	PLEKHG5 DIAPH1	8.52e-06	2	102	2	24126053
Pubmed	Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19155504
Pubmed	Surfactant Protein A can Affect the Surface Tension of the Eustachian Tube and Macrophage Migration.	SFTPA2 SFTPA1	8.52e-06	2	102	2	36102297
Pubmed	Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.	PTCRA NOTCH3	8.52e-06	2	102	2	11891328
Pubmed	Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus.	HES1 NEUROG3	8.52e-06	2	102	2	20235092
Pubmed	Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.	SFTPA2 SFTPA1	8.52e-06	2	102	2	17307210
Pubmed	GAK rs1564282 and DGKQ rs11248060 increase the risk for Parkinson's disease in a Chinese population.	GAK DGKQ	8.52e-06	2	102	2	23618683
Pubmed	Surfactant protein A modulates induction of regulatory T cells via TGF-β.	SFTPA2 SFTPA1	8.52e-06	2	102	2	22474025
Pubmed	Constitutive expression of the pre-TCR enables development of mature T cells.	FOXN1 PTCRA	8.52e-06	2	102	2	16641111
Pubmed	The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.	SFTPA2 SFTPA1	8.52e-06	2	102	2	11504713
Pubmed	Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.	SFTPA2 SFTPA1	8.52e-06	2	102	2	38553537
Pubmed	Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.	NOTCH3 NOTCH4	8.52e-06	2	102	2	17696940
Pubmed	Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.	SFTPA2 SFTPA1	8.52e-06	2	102	2	33510368
Pubmed	Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19392648
Pubmed	Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.	SFTPA2 SFTPA1	8.52e-06	2	102	2	20448439
Pubmed	Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.	SFTPA2 SFTPA1	8.52e-06	2	102	2	20048345
Pubmed	Functional assessment and phenotypic heterogeneity of SFTPA1 and SFTPA2 mutations in interstitial lung diseases and lung cancer.	SFTPA2 SFTPA1	8.52e-06	2	102	2	32855221
Pubmed	Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.	SFTPA2 SFTPA1	8.52e-06	2	102	2	11342662
Pubmed	Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.	SFTPA2 SFTPA1	8.52e-06	2	102	2	9126996
Pubmed	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.	SFTPA2 SFTPA1	8.52e-06	2	102	2	24080545
Pubmed	Lung development in the mouse embryo.	SFTPA2 SFTPA1	8.52e-06	2	102	2	2050021
Pubmed	Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.	SFTPA2 SFTPA1	8.52e-06	2	102	2	1443158
Pubmed	Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.	SFTPA2 SFTPA1	8.52e-06	2	102	2	27835691
Pubmed	Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.	SFTPA2 SFTPA1	8.52e-06	2	102	2	31350355
Pubmed	Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.	SFTPA2 SFTPA1	8.52e-06	2	102	2	23069847
Pubmed	Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19055785
Pubmed	Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.	NOTCH3 NOTCH4	8.52e-06	2	102	2	25658374
Pubmed	Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.	SFTPA2 SFTPA1	8.52e-06	2	102	2	34484180
Pubmed	Surfactant protein A limits Pneumocystis murina infection in immunosuppressed C3H/HeN mice and modulates host response during infection.	SFTPA2 SFTPA1	8.52e-06	2	102	2	15857803
Pubmed	Surfactant protein-A reduces translocation of mediators from the lung into the circulation.	SFTPA2 SFTPA1	8.52e-06	2	102	2	20715984
Pubmed	Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.	SFTPA2 SFTPA1	8.52e-06	2	102	2	19335775
Pubmed	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.	SFTPA2 SFTPA1	8.52e-06	2	102	2	12922979
Interaction	TOP3B interactions	ABCA2 OBSCN PER1 DGKQ ATG2A FHIP1B ZBED3 PLEKHG5 PPP1R26 ZCCHC14 MST1R GAS2L1 SCAF1 ARHGEF40 ARVCF SEC16A STRN4 LRP3 WDR90 RPP25L CABIN1	8.83e-06	1470	100	21	int:TOP3B
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN ARHGEF25 ARHGEF17 ARHGEF40	6.77e-05	66	60	4	722
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CD93 SFTPA2 SFTPA1	3.39e-04	41	60	3	1298
GeneFamily	Collectins	SFTPA2 SFTPA1	4.79e-04	10	60	2	491
GeneFamily	HOXL subclass homeoboxes	HOXA4 HOXA10 HOXC12	6.84e-04	52	60	3	518
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL3 HES1 NOTCH3 NOTCH4	3.79e-07	16	102	4	MM1296
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL3 HES1 NOTCH3 NOTCH4	3.79e-07	16	102	4	M2207
Coexpression	GSE29618_PDC_VS_MDC_UP	MIA3 MAP1A BSPRY IRF7 CSF2RB PIAS3 SETBP1 NOTCH4	1.10e-06	198	102	8	M4951
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	ALX3 HMX2 HOXA4 HOXA10 HOXC12 DMRTA1 NEUROG3 NOTCH3	1.15e-05	272	102	8	M1938
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	ALX3 HMX2 HOXA4 HOXA10 HOXC12 DMRTA1 NEUROG3 NOTCH3	1.49e-05	282	102	8	MM822
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP1A PTCRA BSPRY IRF7 CSF2RB SETBP1 SFTPA1 NOTCH4	1.11e-08	185	102	8	308a98f111895071d8772bc010554471cc12fab2
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALX3 COL4A3 ARHGEF17 MST1R WDR90 CARNS1 NOTCH3	2.36e-07	185	102	7	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALX3 COL4A3 ARHGEF17 MST1R WDR90 CARNS1 NOTCH3	2.36e-07	185	102	7	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	facs-Heart-LA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF467 ARHGEF17 ARVCF KCNQ4 NOTCH3 AGAP2 PDZD2	2.44e-07	186	102	7	e2ba9f3518d87a44537a57a648df17ab98fbbb39
ToppCell	facs-Heart-LA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF467 ARHGEF17 ARVCF KCNQ4 NOTCH3 AGAP2 PDZD2	2.44e-07	186	102	7	fda3415222f688ef5cd8de4b0b79daa2493c585f
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C2CD4B HOXA4 CD93 GAS2L1 SCAF1 CSF2RB NOTCH4	3.99e-07	200	102	7	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	Healthy_donor-HSPC\|World / disease group, cell group and cell class (v2)	TEDC2 BSPRY ARHGEF17 HOXA4 HOXA10 NOTCH3	2.40e-06	167	102	6	70630ebdfee8171d625811844f8a7c94736d101e
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	TEDC2 ARHGEF40 PIAS3 PROB1 LOXL3 FOXD1	2.40e-06	167	102	6	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	390C-Myeloid-Dendritic-pDC\|390C / Donor, Lineage, Cell class and subclass (all cells)	PTCRA BSPRY IRF7 CSF2RB SETBP1 NOTCH4	2.48e-06	168	102	6	5a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALX3 COL3A1 PTCRA HOXA10 ARHGEF40 LOXL3	2.66e-06	170	102	6	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCRA CD93 MST1R HES1 DESI1 NOTCH3	3.04e-06	174	102	6	a9f34d1237f335d27c5560ff514368f4709f9144
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|myeloid / Lineage, cell class and subclass	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	3.46e-06	178	102	6	f75591988bbbeba073b66329a3437cb9b02f7648
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 ARHGEF17 KCNQ4 LOXL3 NOTCH3 PDZD2	3.58e-06	179	102	6	56db12467b445f2b8ef92af50779eeab10413eb2
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	3.69e-06	180	102	6	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	3.94e-06	182	102	6	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	3.94e-06	182	102	6	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MAP1A PTCRA IRF7 CSF2RB SFTPA1 NOTCH4	4.06e-06	183	102	6	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 NCKAP5 ARHGEF25 ARHGEF17 ARVCF ADAMTS15	4.33e-06	185	102	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 NCKAP5 ARHGEF25 ARHGEF17 ARVCF ADAMTS15	4.33e-06	185	102	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 NCKAP5 ARHGEF25 ARHGEF17 ARVCF ADAMTS15	4.33e-06	185	102	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	Healthy_donor-pDC\|Healthy_donor / disease group, cell group and cell class (v2)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.33e-06	185	102	6	7fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	4.46e-06	186	102	6	a07694caf7fede06a47636725bcc7f09909cdf07
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.46e-06	186	102	6	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|Dendritic_cell / Lineage, cell class and subclass	MAP1A PTCRA IRF7 CSF2RB SETBP1 NOTCH4	4.46e-06	186	102	6	858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.46e-06	186	102	6	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC\|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	4.60e-06	187	102	6	068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	MAP1A PTCRA IRF7 IGFLR1 CSF2RB NOTCH4	4.60e-06	187	102	6	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	C2CD4B SPNS2 NCKAP5 FCN3 CD93 NOTCH4	4.74e-06	188	102	6	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.74e-06	188	102	6	89411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	4.74e-06	188	102	6	26405ef1b934744e672c642db78834c21d3ba28f
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.74e-06	188	102	6	de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.74e-06	188	102	6	879054b780378ae05be68e597c77c931bf0ade03
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.89e-06	189	102	6	209cae68d78c8f72479b169e27c3ff7e143adece
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.89e-06	189	102	6	a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCell	COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease group, lineage and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.89e-06	189	102	6	c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCell	Control-Myeloid-pDC\|Control / Disease group, lineage and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.89e-06	189	102	6	46770b99da42f11f10cfc67cea8562342d60b867
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	4.89e-06	189	102	6	98ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 ARHGEF17 KCNQ4 LOXL3 NOTCH3 PDZD2	4.89e-06	189	102	6	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	MAP1A PTCRA IRF7 IGFLR1 CSF2RB NOTCH4	5.04e-06	190	102	6	dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	MAP1A PTCRA IRF7 IGFLR1 CSF2RB NOTCH4	5.04e-06	190	102	6	6892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell	COVID-19_Moderate-pDC\|World / disease group, cell group and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	5.19e-06	191	102	6	93adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCell	(011)_pDC\|World / immune cells in Peripheral Blood (logTPM normalization)	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	5.19e-06	191	102	6	d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCell	COVID-19_Moderate-pDC\|COVID-19_Moderate / disease group, cell group and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	5.19e-06	191	102	6	9d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCell	Healthy-pDC\|World / disease group, cell group and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	5.19e-06	191	102	6	6e1d825dc33b915b95f13ccd237a552160a4be98
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HCN2 ARHGEF17 ARVCF LOXL3 NOTCH3 PDZD2	5.35e-06	192	102	6	158cc5736f154da1cb3186ffbf186eae10483e48
ToppCell	Healthy-pDC\|Healthy / disease group, cell group and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	5.35e-06	192	102	6	33d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HCN2 ARHGEF17 ARVCF LOXL3 NOTCH3 PDZD2	5.35e-06	192	102	6	f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1A PTCRA BSPRY IRF7 IGFLR1 CSF2RB	5.51e-06	193	102	6	5a4accf3af236ff285942163c45277a80263f421
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TTYH1 MAP1A PTCRA IRF7 IGFLR1 CSF2RB	5.68e-06	194	102	6	bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell	medial-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TTYH1 MAP1A PTCRA IRF7 IGFLR1 CSF2RB	5.68e-06	194	102	6	d58be6454a0795d6771036a1620553a153861615
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TTYH1 MAP1A PTCRA IRF7 IGFLR1 CSF2RB	5.68e-06	194	102	6	0117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1A PTCRA BSPRY IRF7 IGFLR1 CSF2RB	5.85e-06	195	102	6	de60fa0c69c835f0b1d6d2dba1a1acd73246b001
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	C2CD4B SPNS2 NCKAP5 FCN3 CD93 NOTCH4	5.85e-06	195	102	6	dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCell	ASK454-Endothelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.02e-06	196	102	6	14dd6956ef420b660be0baf52a66960e57d75d16
ToppCell	ASK454-Endothelial-Endothelium\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.02e-06	196	102	6	2b777a2026b56839112fd179f2db482c49f4594a
ToppCell	mild-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAP1A PTCRA IRF7 CSF2RB SETBP1 NOTCH4	6.20e-06	197	102	6	0cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.20e-06	197	102	6	7caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.20e-06	197	102	6	951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell	390C-Endothelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.20e-06	197	102	6	aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell	severe-pDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	6.38e-06	198	102	6	22da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCell	(6)_Endothelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.38e-06	198	102	6	f38f49d532fa6211f57e36ee494478bdd3f4f89c
ToppCell	severe-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAP1A PTCRA BSPRY IRF7 SETBP1 NOTCH4	6.38e-06	198	102	6	3c4820a8391088682fb3e47b914f872533bae227
ToppCell	368C-Endothelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.38e-06	198	102	6	9a2c2201baee51581733e183065298a97eba4553
ToppCell	Sepsis-Leuk-UTI-Others\|Leuk-UTI / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	e45fe91f1d1c47a305b0f39d808730723852af00
ToppCell	Control-Control-Others-RBC\|Control / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	eb4c52d04f572433c0239bf479d0040a309939a1
ToppCell	MS-IIF-Myeloid-pDC\|IIF / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	e262ee854e64d87460bee810c14d6cbe744460e8
ToppCell	Sepsis-Leuk-UTI-Others-RBC\|Leuk-UTI / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	d9b517199a646c9461c615412ad5b58cf4bed7c8
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	edb68a4f622a494f22fd7b25bc40ae0d58456cdb
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	523e01f6a0abd9820697572e042a381aae8932dc
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	448dd5a27d57627468c6b8347f1b6b1005aea004
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	0d0d5cb821db16514192ad536849a8a04e22e637
ToppCell	Sepsis-ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	a199e67438eeed903d0996605591ec54400fdd66
ToppCell	Control-Control-Myeloid-pDC\|Control / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 IGFLR1 NOTCH4	6.57e-06	199	102	6	8e9cac53fabe497ffa27fca0627eafe883af2534
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	45f9c03d2ed2d98d66086fb0251bd24e30c6f775
ToppCell	COVID-19-COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease, condition lineage and cell class	MAP1A PTCRA BSPRY IRF7 CSF2RB NOTCH4	6.57e-06	199	102	6	9de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.57e-06	199	102	6	dfd60380a29f99e187050933ee5252ec11c68a32
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C2CD4B SPNS2 FCN3 CD93 HES1 NOTCH4	6.76e-06	200	102	6	2989325b0e78ab42f362cfb59e34a4fce7f8e869
ToppCell	(54)_pDC\|World / shred on Cell_type and subtype	MAP1A PTCRA IRF7 CSF2RB SFTPA1 NOTCH4	7.36e-06	203	102	6	b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCell	Control-Endothelial-Endothelial-Activated_Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	C2CD4B SPNS2 CD93 ARHGEF40 NOTCH4	8.75e-06	121	102	5	a5962d1c476e6966870832b72d511607e047248b
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	NCKAP5 ARHGEF17 SFTPA2 ARVCF HES1	1.84e-05	141	102	5	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	MAP1A PTCRA IRF7 CSF2RB SETBP1	3.17e-05	158	102	5	2af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCell	facs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RETREG2 SPNS2 HOXA4 CD93 TRIM47	3.79e-05	164	102	5	5ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	COL4A3 ABCA2 PKDCC GAS2L1 PDZD2	3.90e-05	165	102	5	f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A PTCRA IRF7 IGFLR1 HCN2	3.90e-05	165	102	5	e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFRSF6B PKDCC DGKQ HOXA10 KCNQ4	4.02e-05	166	102	5	3b67064a5149e72f895344d938c64b8ff65247f5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG2A ARHGEF40 CSF2RB MROH7 HES1	4.13e-05	167	102	5	9b9b4cad0b35d121256176600ea4705759c105d3
ToppCell	mild_COVID-19-HSPC\|mild_COVID-19 / disease group, cell group and cell class (v2)	C2CD4B SPNS2 BSPRY HOXA10 PDZD2	4.25e-05	168	102	5	90b33962adb77d8326dee403712118398b4d1315
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	MAP1A PTCRA IRF7 HCN2 SETBP1	4.25e-05	168	102	5	4bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	MAP1A PTCRA IRF7 CSF2RB NOTCH4	4.25e-05	168	102	5	cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MAP1A PTCRA IRF7 MST1R STKLD1	4.50e-05	170	102	5	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	368C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MAP1A PTCRA IRF7 ZCCHC14 AGAP2	4.63e-05	171	102	5	f3bf5805823d5733b58742172e7668725ce82931
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1A PTCRA IRF7 IGFLR1 CSF2RB	4.63e-05	171	102	5	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	COVID-pDC\|COVID / Condition, Cell_class and T cell subcluster	MAP1A PTCRA BSPRY IRF7 NOTCH4	4.76e-05	172	102	5	3ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell	Healthy_donor-HSPC\|Healthy_donor / disease group, cell group and cell class (v2)	TEDC2 BSPRY ARHGEF17 HOXA4 NOTCH3	4.76e-05	172	102	5	bc7549faadfc92c683c0e26bea380458706774b5
ToppCell	COVID-pDC-\|COVID / Condition, Cell_class and T cell subcluster	MAP1A PTCRA BSPRY IRF7 NOTCH4	4.76e-05	172	102	5	a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	OBSCN ARHGEF17 KCNQ4 SETBP1 NOTCH3	4.89e-05	173	102	5	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PERM1 ARHGEF25 KCNQ4 SETBP1 NOTCH3	4.89e-05	173	102	5	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCRA CD93 MST1R HES1 NOTCH3	5.02e-05	174	102	5	0fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCRA CD93 MST1R HES1 NOTCH3	5.02e-05	174	102	5	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 BICDL2 BSPRY NCKAP5 MST1R	5.02e-05	174	102	5	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
Drug	Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	MAP1A DGKQ ZCCHC14 HOXA10 ARHGEF40 L3MBTL1 FBXO41 CABIN1	2.56e-06	193	102	8	5273_UP
Drug	PF-00539758-00 [351321-34-1]; Up 200; 10uM; MCF7; HT_HG-U133A	COL3A1 ABCA2 PTCRA GALR3 PER1 DBP L3MBTL1 ARVCF	2.87e-06	196	102	8	6416_UP
Drug	Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A	COL4A3 ABCA2 PTCRA TNFRSF6B ARHGEF17 L3MBTL1 KRT75 DLL3	2.98e-06	197	102	8	2279_UP
Drug	Niflumic acid [4394-00-7]; Up 200; 14.2uM; PC3; HT_HG-U133A	PTCRA PER1 RGS12 L3MBTL1 ARVCF LRP3 CABIN1 AGAP2	3.21e-06	199	102	8	5071_UP
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A	ABCA2 TEDC2 BSPRY PER1 KRT75 DIAPH1 CABIN1	3.01e-05	197	102	7	6563_UP
Drug	U0125; Down 200; 1uM; PC3; HG-U133A	COL3A1 MBOAT7 CD93 ARVCF NFATC3 STRN4 DESI1	3.01e-05	197	102	7	663_DN
Drug	Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A	ABCA2 MAP1A PTCRA ARVCF KCNQ4 SETBP1 CABIN1	3.01e-05	197	102	7	5249_UP
Drug	Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	PTCRA TNFRSF6B ARHGEF17 MST1R L3MBTL1 ARVCF AGAP2	3.11e-05	198	102	7	3865_UP
Drug	Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; HL60; HT_HG-U133A	PTCRA TEDC2 TNFRSF6B ZNF467 COLQ HOXA10 NFATC3	3.11e-05	198	102	7	1266_UP
Drug	Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; HL60; HT_HG-U133A	ABCA2 PTCRA MBOAT7 TEDC2 COLQ NFATC3 LRP3	3.11e-05	198	102	7	1340_UP
Drug	Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A	COL3A1 PTCRA PER1 RGS12 L3MBTL1 NFATC3 FBXO41	3.21e-05	199	102	7	3516_UP
Drug	dopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A	ALX3 GALR3 TEDC2 DBP PPP1R26 LRP3 CABIN1	3.21e-05	199	102	7	491_DN
Drug	Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	COL4A3 MAP1A PER1 DGKQ RGS12 CSF2RB AGAP2	3.32e-05	200	102	7	5626_UP
Disease	O-methylcatechol sulfate measurement	SPNS2 CARNS1	1.14e-05	2	100	2	EFO_0022102
Disease	X-24513 measurement	SPNS2 CARNS1	3.40e-05	3	100	2	EFO_0022133
Disease	X-21658 measurement	SPNS2 CARNS1	6.79e-05	4	100	2	EFO_0022121
Disease	pulmonary edema (is_implicated_in)	IL13 SFTPA1	6.79e-05	4	100	2	DOID:11396 (is_implicated_in)
Disease	Carcinoma, Pancreatic Ductal	HES1 NOTCH3 NOTCH4	7.26e-05	24	100	3	C0887833
Disease	brain cancer (implicated_via_orthology)	L3MBTL1 HES1 NOTCH3	9.28e-05	26	100	3	DOID:1319 (implicated_via_orthology)
Disease	level of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum	SFTPA2 SFTPA1	1.13e-04	5	100	2	OBA_2042200
Disease	level of prosaposin in blood serum	SFTPA2 SFTPA1	1.13e-04	5	100	2	OBA_2044552
Disease	Myeloid Leukemia, Chronic	ASXL1 PER1 SETBP1	1.29e-04	29	100	3	C0023473
Disease	newborn respiratory distress syndrome (biomarker_via_orthology)	SFTPA2 SFTPA1	1.69e-04	6	100	2	DOID:12716 (biomarker_via_orthology)
Disease	level of complement component C1q receptor in blood serum	COL4A3 CD93	1.69e-04	6	100	2	OBA_2040369
Disease	2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement	SPNS2 CARNS1	1.69e-04	6	100	2	EFO_0800111
Disease	newborn respiratory distress syndrome (is_implicated_in)	SFTPA2 SFTPA1	2.36e-04	7	100	2	DOID:12716 (is_implicated_in)
Disease	central nervous system cancer (implicated_via_orthology)	HES1 NOTCH3	2.36e-04	7	100	2	DOID:3620 (implicated_via_orthology)
Disease	leukocyte immunoglobulin-like receptor subfamily B member 4 measurement	SFTPA2 SFTPA1	3.14e-04	8	100	2	EFO_0801768
Disease	hemangiopericytoma (is_marker_for)	HES1 NOTCH4	4.03e-04	9	100	2	DOID:264 (is_marker_for)
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	SFTPA2 SFTPA1	7.34e-04	12	100	2	EFO_0801493
Disease	granulins measurement	SFTPA2 SFTPA1	7.34e-04	12	100	2	EFO_0008141
Disease	Hamman-Rich syndrome	SFTPA2 SFTPA1	1.01e-03	14	100	2	C0085786
Disease	inositol measurement	SETBP1 NOTCH3	1.01e-03	14	100	2	EFO_0010504
Disease	bacterial pneumonia (biomarker_via_orthology)	SFTPA2 SFTPA1	1.01e-03	14	100	2	DOID:874 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	OBSCN PER1 HOXA4 ZCCHC14 SETBP1 MROH7 HES1 SPOCD1 NOTCH3 NOTCH4 AGAP2	1.04e-03	1074	100	11	C0006142
Disease	asthma (biomarker_via_orthology)	IL13 SFTPA2 SFTPA1	1.07e-03	59	100	3	DOID:2841 (biomarker_via_orthology)
Disease	urate measurement, bone density	PKDCC HCN2 CSF2RB SEC16A DIAPH1 CABIN1 NOTCH4 PDZD2	1.23e-03	619	100	8	EFO_0003923, EFO_0004531
Disease	Cerebrovascular accident	COL3A1 ZCCHC14 NOTCH3	1.24e-03	62	100	3	C0038454
Disease	alpha-L-iduronidase measurement	GAK DGKQ	1.50e-03	17	100	2	EFO_0020139
Disease	atopic eczema	IL13 TNFRSF6B NCKAP5 CSF2RB DMRTA1	1.70e-03	252	100	5	EFO_0000274
Disease	Juvenile Myelomonocytic Leukemia	ASXL1 SETBP1	1.87e-03	19	100	2	C0349639
Disease	Familial Idiopathic Pulmonary Fibrosis	SFTPA2 SFTPA1	2.08e-03	20	100	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	SFTPA2 SFTPA1	2.29e-03	21	100	2	C1800706
Disease	lung disease (is_marker_for)	IL13 SFTPA1	2.51e-03	22	100	2	DOID:850 (is_marker_for)
Disease	Colorectal Carcinoma	COL3A1 OBSCN PER1 CD93 SETBP1 ADAMTS15 DMRTA1 TSKS	2.69e-03	702	100	8	C0009402
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	TSKS PDZD2	2.99e-03	24	100	2	EFO_0003761, EFO_0005658
Disease	Ureteral obstruction	COL3A1 HES1	2.99e-03	24	100	2	C0041956
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SFTPA2 SFTPA1	2.99e-03	24	100	2	DOID:3827 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPPGSKIPSPGGGCV	TTYH1	76	Q9H313
AQGDSPPPCPGGAGT	CCDC185	141	Q8N715
PPPCPGGAGTPLSGT	CCDC185	146	Q8N715
GPSLPGLSPGACSLP	ARHGEF40	1431	Q8TER5
GLSSGPCSPGPPGPV	ARHGEF25	61	Q86VW2
GPLGPGPGDGCFTLP	ARVCF	216	O00192
TPGSPGCAGSPGLPG	COL4A3	416	Q01955
GSGSPGGPCLVSPEG	ALX3	251	O95076
SCTMGPVSLGPPSGP	CD93	466	Q9NPY3
LPCSDGPSPGPGLAV	CARNS1	216	A5YM72
GSPRPGSPACSPVLG	DGKQ	16	P52824
GSGPLPGPPSLSSGS	AGAP2	361	Q99490
SSGAGGPAPRCAPPS	CCSAP	66	Q6IQ19
SFGPGPGPGAPRSPC	DLL3	36	Q9NYJ7
LPGGVCISSPPSLPG	DIAPH1	621	O60610
PSPPVGGPAGSLGSC	ATG2A	1326	Q2TAZ0
ACGHPEPRGGPSTPG	ASXL1	671	Q8IXJ9
GVPGGPSGDPTSRCG	ADAMTS15	161	Q8TE58
PPSCGAPGLGSGTIP	MROH7	21	Q68CQ1
PVAAPPAPGSSGGGC	FOXD1	396	Q16676
LPLSGSFGPGGPCGT	ARHGEF17	1691	Q96PE2
VLLPSCPGAPGSPGE	FCN3	41	O75636
LGGSESPGPAPCSPG	FHIP1B	511	Q8N612
SPCMQGSLGSPGPPG	COLQ	91	Q9Y215
GGGAGPPHDPPSCQS	HOXC12	151	P31275
ALGCPALPTGVGGTP	PTCRA	11	Q6ISU1
ACVGGPSPSPSPGSS	KRBA1	631	A5PL33
PLSPCPGGTPAGSSG	KRBA1	681	A5PL33
CPGGGPAVVSCVPGP	LOXL3	271	P58215
QPVCPAGGSGGPPSS	MAP1A	2411	P78559
PPAPHCGELGSPGGS	NEUROG3	151	Q9Y4Z2
GGPGTKSGEPLCPPL	DNAAF2	511	Q9NVR5
LPPPGSCAAEGSPGT	MESD	26	Q14696
APLPGPGSGSGSACG	KCNQ4	56	P56696
PDAPLGTLCGPRGPG	C2CD4B	136	A6NLJ0
GTLCGPRGPGPATPA	C2CD4B	141	A6NLJ0
PGESFCPGGVPSPGP	PER1	16	O15534
PTGLCGVGAVTSPGP	PER1	506	O15534
LGPREPSSASPGGCP	L3MBTL1	586	Q9Y468
SPGPPAGGVSCPEKG	PDZD2	2521	O15018
FPCLGTPKGSGGSGP	HMX2	86	A2RU54
PPGLSGPSCRSFPGS	NOTCH3	1316	Q9UM47
GPSCRSFPGSPPGAS	NOTCH3	1321	Q9UM47
TCLGGFASPGPVPPS	IL13	26	P35225
SAPASEPPGSLCPGG	LRP3	201	O75074
RAGGGPTLQCPPPSS	MBOAT7	271	Q96N66
AGAPGPGLGLCSSSP	EP400P1	141	Q6ZTU2
DSPPPPTLACGSGGG	HOXA10	271	P31260
GGPPGSASPSTPACL	IRF7	381	Q92985
PCPGQSSGGAESPAP	FAM182B	81	Q5T319
PSTGDLTGPGPCPRG	OBSCN	6246	Q5VST9
PGRPKPGPCSSPGSA	OBSCN	7106	Q5VST9
ASSGPPGCPGDARPS	GALR3	326	O60755
GPLFSPGGQPAPCGS	GAK	1056	O14976
TPSLCPGLASGPPGA	CSF2RB	741	P32927
GSGSGPGPGPLCPEH	BSPRY	11	Q5W0U4
PGPGASLPSSSGPGL	CABIN1	1331	Q9Y6J0
SPCPGMGGPLDAPGS	GAS2L1	606	Q99501
AATSGSGGCPPAPGL	DMRTA1	66	Q5VZB9
SSCPPGGTLLGPPDS	DESI1	56	Q6ICB0
PCGGGAVTPTPAAGG	IGFLR1	91	Q9H665
CTGRTPGPPASGAGG	ABCA2	351	Q9BZC7
GPSFPSGPLSGGASP	BICDL2	6	A1A5D9
ALSGVGLPGCPKGPP	MAP3K12	521	Q12852
GPGPCPGPASASPAS	FBXO41	176	Q8TF61
RTPAPSPGPGSCGSA	DBP	146	Q10586
SPGSPGPPGICESCP	COL3A1	131	P02461
CCGPGTAPGPGAGVP	SBK1	16	Q52WX2
SCRGAASGPAPGPGP	HCN2	126	Q9UL51
PATPGVPAGGSAPAC	HOXA4	161	Q00056
GPGASPPSQFSSCPG	PERM1	116	Q5SV97
PPPGGAPCKLGSQAG	HES1	196	Q14469
GGPAGCPAPGSTPLK	IER5	226	Q5VY09
EPSAPGGGGSPGACP	RTN3	21	O95197
GCGPGPGPPRELSFT	TRIM47	346	Q96LD4
PGSPGPGPRLGCAAL	PKDCC	121	Q504Y2
SFGPSPVSGGECSPP	MIA3	1666	Q5JRA6
CPVGRPPGASPSCGG	TEDC2	331	Q7L2K0
CGSGPEAGVKSPSPP	NCKAP5	916	O14513
LLGCPPPGLSGSGPI	FOXN1	396	O15353
GSPPDGVKCSPGGPV	RETREG2	416	Q8NC44
RAPTGPPGTPGTPGC	SPNS2	66	Q8IVW8
PPGTPGTPGCAATAK	SPNS2	71	Q8IVW8
CPPKLVPGSGGGPGS	PPP1R26	186	Q5T8A7
CVGSPGIPGTPGSHG	SFTPA2	26	Q8IWL1
CAPPSSSGPTQPGKG	PROB1	996	E7EW31
GGPDCLTPPAPKGCG	NOTCH4	1121	Q99466
CVGSPGIPGTPGSHG	SFTPA1	26	Q8IWL2
GGIALSPPPSCGVGT	AMMECR1	81	Q9Y4X0
ARGGQCPGLGPAPTP	ZBED3	21	Q96IU2
GHGGPLPSGPSLTGC	PIAS3	606	Q9Y6X2
GAPSPGSGPGLVGCL	PLEKHG5	931	O94827
QSFPGAPPACKTGPG	WDR90	1006	Q96KV7
GTTPPGQKSPSGPFC	RGS12	1286	O14924
EPGPGCVTPGPALGF	SEC16A	1981	O15027
PGLPPGGSPQLGCTT	STKLD1	661	Q8NE28
LPGSLPLGGCGSTPP	SCAF1	1166	Q9H7N4
PLGGCGSTPPTPTGL	SCAF1	1171	Q9H7N4
TGDGPQPGSPCGPVG	SPOCD1	291	Q6ZMY3
PGAPPGLGSMPSSSC	RPP25L	136	Q8N5L8
GSPLTSPGGSPGGCP	NFATC3	206	Q12968
AATSQGCPGPPGSPD	TSKS	276	Q9UJT2
GTGAPKCGSDSTPPP	nan	41	Q8N1X5
KGAPGPGGALPTCPA	ZCCHC14	36	Q8WYQ9
PTAGSCQPSPLSPGG	nan	51	Q6ZR54
SCRPLGSGAGPGPTG	STRN4	16	Q9NRL3
PGCAGEPLLSTPGPG	SETBP1	31	Q9Y6X0
ACGPGPHGPPGDTDT	MST1R	106	Q04912
QCGPAGGSPPGIDPT	WBP1L	136	Q9NX94
APGGPGCGPGSDPVV	ZNF467	406	Q7Z7K2
SCPPGAGVIAPGTPS	TNFRSF6B	131	O95407
GGFSGPSFPVCPPGG	KRT75	106	O95678