Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

GPR89B ANO2 AQP10 SLC9A8 ABCA3 CALHM5 ABCA4 SLC2A9 XKR9 SLC26A9 SLCO1B3 ATP8B1 TTYH3 SLC43A3 ABCA10 ABCA8 SVOPL SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC22A9 SLC7A2 MFSD2A ABCG1 SIDT2 SLC9A2 ABCB10 NALCN KCND1 KCND2 KCND3 SV2A ATRAID SCN1A SCN2A ATP2C2 SLC22A10 SCN5A SCN8A TMEM37 SCN10A GPR89A SLC13A5 NIPA2 SLC49A3 CACNG5 SLC41A1 SLC16A7 LMBRD1 ANO3 MFSD5 PLTP

8.19e-26128917958GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

GPR89B ANO2 AQP10 SLC9A8 ABCA3 CALHM5 ABCA4 SLC2A9 SLC26A9 SLCO1B3 TTYH3 SLC43A3 ABCA10 ABCA8 SVOPL SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC22A9 SLC7A2 MFSD2A ABCG1 SIDT2 SLC9A2 ABCB10 NALCN KCND1 KCND2 KCND3 SV2A ATRAID SCN1A SCN2A ATP2C2 SLC22A10 SCN5A SCN8A TMEM37 SCN10A GPR89A SLC13A5 NIPA2 SLC49A3 CACNG5 SLC41A1 SLC16A7 ANO3 MFSD5

2.91e-24118017954GO:0022857
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 GLP1R OR6C1 GPR75 OR5H8 HRH4 OR5H2 OR6T1 ACKR1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

2.59e-1988417942GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 HLA-DRB3 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 MET OR52I2 TAS2R16 CD3D OR51D1 OR4S1 OR14A2 MS4A2 CD27 GLP1R OR6C1 GPR75 OR5H8 TLR5 ANTXR1 HRH4 OR5H2 OR6T1 ACKR1 MUSK OR52B6 OR2AE1 GPR119 GPR151 CNR2 LILRA4

3.76e-19135317951GO:0004888
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GPR89B ANO2 SLC9A8 CALHM5 SLC2A9 SLC26A9 TTYH3 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 MFSD2A SLC9A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A GPR89A SLC13A5 NIPA2 CACNG5 SLC41A1 ANO3

2.29e-1479317934GO:0015075
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO2 AQP10 SLC9A8 SLC2A9 SLC26A9 TTYH3 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 MFSD2A SLC9A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 ANO3 MFSD5

3.81e-1475817933GO:0015318
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A8 ABCA3 ABCA4 SLC2A9 SLC26A9 SLCO1B3 ABCA10 ABCA8 SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC22A9 MFSD2A ABCG1 SLC9A2 ABCB10 ATP2C2 SLC22A10 SLC13A5 SLC41A1 SLC16A7

1.19e-1247717925GO:0022804
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC9A8 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 MFSD2A SLC9A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1

4.83e-1246517924GO:0046873
GeneOntologyMolecularFunctionlipid transporter activity

ANO2 ABCA3 ABCA4 XKR9 SLCO1B3 ATP8B1 SLC43A3 ABCA10 ABCA8 SLC22A7 SLC22A9 MFSD2A ABCG1 SLC22A10 ANO3 PLTP

2.64e-1119617916GO:0005319
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC9A8 CALHM5 SLC2A9 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 MFSD2A SLC9A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1

4.92e-1166417927GO:0008324
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC9A8 SLC2A9 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 MFSD2A SLC9A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1

7.61e-1162717926GO:0022890
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A8 SLC2A9 SLC26A9 SLCO1B3 SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC22A9 MFSD2A SLC9A2 SLC22A10 SLC13A5 SLC41A1 SLC16A7

1.92e-1029617918GO:0015291
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A8 SLC5A4 SLC5A5 SLC6A2 MFSD2A SLC9A2 NALCN SCN1A SCN2A SCN5A SCN8A SCN10A SLC13A5 SLC41A1

4.64e-1017117914GO:0015081
GeneOntologyMolecularFunctionolfactory receptor activity

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

2.07e-0943117920GO:0004984
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GPR89B ANO2 CALHM5 SLC26A9 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5 ANO3

6.05e-0945917920GO:0005216
GeneOntologyMolecularFunctionchannel activity

GPR89B ANO2 AQP10 CALHM5 SLC26A9 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5 ANO3

1.10e-0852517921GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GPR89B ANO2 AQP10 CALHM5 SLC26A9 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5 ANO3

1.14e-0852617921GO:0022803
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO2 ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3

1.63e-08511798GO:0140303
GeneOntologyMolecularFunctionphospholipid transporter activity

ANO2 ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3 PLTP

2.05e-08741799GO:0005548
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

GPR89B CACNG3 CACNG2 KCND1 KCND2 KCND3 SCN1A SCN2A TMEM37 SCN10A GPR89A CACNG5

9.44e-0818217912GO:0005244
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN1A SCN2A SCN5A SCN8A SCN10A

9.47e-08261796GO:0005248
GeneOntologyMolecularFunctionvoltage-gated channel activity

GPR89B CACNG3 CACNG2 KCND1 KCND2 KCND3 SCN1A SCN2A TMEM37 SCN10A GPR89A CACNG5

1.06e-0718417912GO:0022832
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCA4 SLCO1B3 SLC43A3 SLC22A7 SLC22A9 MFSD2A ABCG1 SLC22A10

2.92e-07731798GO:0170055
GeneOntologyMolecularFunctiongated channel activity

GPR89B ANO2 TTYH3 CACNG3 CACNG2 KCND1 KCND2 KCND3 SCN1A SCN2A TMEM37 SCN10A GPR89A CACNG5 ANO3

3.59e-0733417915GO:0022836
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A8 SLC2A9 SLC26A9 SLC4A2 SLC30A6 SLC5A4 SLC5A5 SLC6A2 SLC2A10 MFSD2A SLC9A2 ATP2C2 SLC13A5 SLC41A1

5.89e-0730117914GO:0022853
GeneOntologyMolecularFunctionprostaglandin receptor activity

PTGDR PTGER3 PTGER4 PTGFR

1.96e-06111794GO:0004955
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CALHM5 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A CACNG5

2.75e-0634317914GO:0005261
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND1 KCND2 KCND3

2.82e-0641793GO:0005250
GeneOntologyMolecularFunctionprostanoid receptor activity

PTGDR PTGER3 PTGER4 PTGFR

2.92e-06121794GO:0004954
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA3 ABCA4 ATP8B1 MFSD2A ABCG1

4.55e-06281795GO:0140326
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

4.85e-06491796GO:0140359
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ABCA3 ABCA4 ATP8B1 MFSD2A

5.83e-06141794GO:0140333
GeneOntologyMolecularFunctionsodium channel activity

NALCN SCN1A SCN2A SCN5A SCN8A SCN10A

6.90e-06521796GO:0005272
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GPR89B ANO2 SLC26A9 TTYH3 SLC4A2 SLC5A5 SLC6A2 GPR89A ANO3

9.05e-061511799GO:0008509
GeneOntologyMolecularFunctionicosanoid receptor activity

PTGDR PTGER3 PTGER4 PTGFR

1.04e-05161794GO:0004953
GeneOntologyMolecularFunctionflippase activity

ABCA3 ABCA4 ATP8B1 MFSD2A

1.36e-05171794GO:0140327
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A9 SLCO1B3 SLC43A3 SLC22A7 SLC4A2 SLC2A10 SLC22A9 SLC7A2 MFSD2A SLC22A10 SLC13A5 SLC16A7

1.40e-0529317912GO:0008514
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B3 SLC22A7 SLC22A9 SLC22A10

1.73e-05181794GO:0015347
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A9 SLCO1B3 SLC43A3 SLC22A7 SLC22A9 SLC7A2 MFSD2A SLC22A10 SLC13A5 SLC16A7

1.82e-0520717910GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A9 SLCO1B3 SLC43A3 SLC22A7 SLC22A9 SLC7A2 MFSD2A SLC22A10 SLC13A5 SLC16A7

1.89e-0520817910GO:0005342
GeneOntologyMolecularFunctionodorant binding

OR8I2 OR5A1 OR10R2 OR8U8 OR12D3 OR14A2 OR5H8 OR5H2

1.93e-051271798GO:0005549
GeneOntologyMolecularFunction11-cis retinal binding

OPN4 ABCA4 RHO

2.41e-0571793GO:0005502
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA3 ATP8B1 ABCG1 PLTP

2.70e-05201794GO:0008525
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

AQP10 ABCA4 SLCO1B3 SLC6A2 ABCG1 SLC16A7

3.89e-05701796GO:1901618
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

SLC43A3 SLC22A9 MFSD2A SLC22A10

4.84e-05231794GO:0015245
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10 ATP2C2

5.71e-051091797GO:0042626
GeneOntologyMolecularFunctionsymporter activity

SLC2A9 SLC5A4 SLC5A5 SLC6A2 SLC2A10 MFSD2A SLC13A5 SLC16A7

6.35e-051501798GO:0015293
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC2A9 SLC5A4 SLC5A5 SLC6A2 SLC2A10 MFSD2A SLC13A5

9.96e-051191797GO:0015294
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC22A9 ABCG1 SLC22A10

1.47e-04121793GO:0019534
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ANO2 SLC26A9 TTYH3 SLC4A2 SLC5A5 SLC6A2 ANO3 MFSD5

1.58e-041711798GO:0015103
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B3 SLC43A3 SLC22A9 MFSD2A SLC22A10 SLC16A7

1.59e-04901796GO:0008028
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCA3 SLC43A3 ABCA8 ATRAID

2.35e-04341794GO:0042910
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A7 CYP2A13

2.38e-0431792GO:0008389
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN8A

2.40e-04141793GO:0031402
GeneOntologyMolecularFunctionaromatase activity

CYP2A7 CYP2A13 CYP2D7 CYP4B1

2.63e-04351794GO:0070330
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GPR89B ANO2 SLC26A9 TTYH3 GPR89A ANO3

3.32e-041031796GO:0005253
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC2A9 SLC5A4 SLC2A10

4.39e-04171793GO:0005402
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A SCN10A

4.39e-04171793GO:0099508
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

AQP10 SLC2A9 SLC5A4 SLC2A10

5.36e-04421794GO:0015144
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A8 SLC30A6 SLC9A2 SLC41A1

5.87e-04431794GO:0140828
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO2 TTYH3 ANO3

7.22e-04201793GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO2 TTYH3 ANO3

7.22e-04201793GO:0005229
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A9 SLC22A10

7.85e-0451792GO:0015636
GeneOntologyMolecularFunctionprostaglandin E receptor activity

PTGER3 PTGER4

7.85e-0451792GO:0004957
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A4 SLC5A5 SLC6A2 MFSD2A SLC13A5

8.09e-04811795GO:0015370
GeneOntologyMolecularFunctionretinal binding

OPN4 ABCA4 RHO

8.37e-04211793GO:0016918
GeneOntologyMolecularFunctionretinoid binding

OPN4 ABCA4 UGT1A10 RHO

8.93e-04481794GO:0005501
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

ANO2 SLC26A9 TTYH3 SLC4A2 SLC6A2 ANO3

9.28e-041251796GO:0015108
GeneOntologyMolecularFunctionisoprenoid binding

OPN4 ABCA4 UGT1A10 RHO

9.66e-04491794GO:0019840
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP2A7 CYP2A13 CYP2D7 CYP4B1

9.66e-04491794GO:0016712
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO2 XKR9 ANO3

1.10e-03231793GO:0017128
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10 ATP2C2

1.14e-031781797GO:0015399
GeneOntologyMolecularFunctionphosphatidylcholine flippase activity

ABCA3 ATP8B1

1.17e-0361792GO:0140345
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN5A SCN10A

1.17e-0361792GO:0086006
GeneOntologyMolecularFunctionphosphatidylcholine transfer activity

ABCA3 PLTP

1.17e-0361792GO:0120019
GeneOntologyMolecularFunctionhistamine receptor activity

HTR6 HRH4

1.17e-0361792GO:0004969
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A9 SLC5A4 SLC2A10

1.41e-03251793GO:0015149
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A9 SLC5A4 SLC2A10

1.41e-03251793GO:0055056
GeneOntologyMolecularFunctionantiporter activity

SLC9A8 SLC26A9 SLC4A2 SLC30A6 SLC9A2 SLC41A1

1.54e-031381796GO:0015297
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN8A

1.58e-03261793GO:0031420
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A8 SLC30A6 SLC9A2

1.77e-03271793GO:0051139
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND1 KCND2 KCND3

1.77e-03271793GO:0015271
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A9 SLC5A4 SLC2A10

1.77e-03271793GO:0015145
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP2A7 CYP2A13 CYP2D7

1.77e-03271793GO:0008391
GeneOntologyMolecularFunctioncarbohydrate:proton symporter activity

SLC2A9 SLC2A10

2.16e-0381792GO:0005351
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ATP8B1 ABCG1

2.16e-0381792GO:0090554
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A9 SLC5A4 SLC2A10

2.18e-03291793GO:0051119
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNG3 CACNG2 KCND1 KCND2 KCND3 CACNG5

2.51e-031521796GO:0022843
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A9 SLC22A7 SLC13A5

2.65e-03311793GO:0005310
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP2A7 CYP2A13 CYP2D7

3.46e-03341793GO:0008395
GeneOntologyMolecularFunctionimmunoglobulin binding

MS4A2 MS4A1 LILRA4

4.07e-03361793GO:0019865
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A9 SLC4A2

5.84e-03131792GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A9 SLC4A2

5.84e-03131792GO:0140829
GeneOntologyMolecularFunctionepidermal growth factor receptor binding

ARF4 LINGO1 MS4A1

5.88e-03411793GO:0005154
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

HTR6 TAAR2 HRH4

5.88e-03411793GO:0008227
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A8 SLC9A2

6.77e-03141792GO:0015386
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B3 SLC22A7

6.77e-03141792GO:0015132
GeneOntologyMolecularFunctionarylsulfatase activity

GALNS ARSI

6.77e-03141792GO:0004065
GeneOntologyMolecularFunctionAP-2 adaptor complex binding

SIDT2 LMBRD1

6.77e-03141792GO:0035612
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC9A8 SLC2A9 SLC30A6 SLC5A4 SLC2A10 SLC9A2

7.06e-031881796GO:0015078
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8I2 GPR3 NPPA PDE3B OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 MET OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 MS4A2 GLP1R OR6C1 GPR75 OR5H8 HRH4 OR5H2 OR6T1 ACKR1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

1.53e-15139517946GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transport

GPR89B ANO2 NPPA SLC9A8 CALHM5 SLC2A9 SLC26A9 SLCO1B3 ATP8B1 TTYH3 PTGER3 SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC22A9 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SLC22A10 SCN5A SCN8A TMEM37 SCN10A GPR89A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1 ANO3 MFSD5

4.32e-15137417945GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GPR89B ANO2 NPPA SLC9A8 CALHM5 SLC2A9 SLC26A9 ATP8B1 TTYH3 PTGER3 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A GPR89A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1 ANO3

1.04e-14111517940GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ANO2 NPPA SLC9A8 SLC2A9 SLC26A9 TTYH3 PTGER3 SLC4A2 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1 ANO3

4.24e-13101717936GO:0098660
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8I2 OPN4 OR4C6 OR52L1 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 SCN1A OR6C1 OR5H8 SCN10A OR5H2 OR6T1 OR52B6 OR2AE1

7.29e-1258217926GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR8I2 OPN4 ABCA4 OR4C6 OR52L1 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 SCN1A OR6C1 OR5H8 SCN10A OR5H2 OR6T1 ANO3 OR52B6 OR2AE1

2.96e-1172217928GO:0051606
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

NPPA SLC9A8 CALHM5 SLC2A9 PTGER3 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1

3.03e-1194217932GO:0098655
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

NPPA SLC9A8 SLC2A9 PTGER3 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1

8.35e-1192217931GO:0098662
GeneOntologyBiologicalProcesssensory perception

OR8I2 OPN4 ABCA4 OR4C6 OR52L1 MC1R RDH12 OR5A1 OR10C1 ATP8B1 TAS2R38 OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 KCND2 SCN1A OR6C1 OR5H8 SCN8A SCN10A OR5H2 LUM OR6T1 OR52B6 OR2AE1

1.87e-10107217933GO:0007600
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

2.57e-1048517922GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

1.09e-0952417922GO:0009593
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

1.25e-0943217920GO:0050911
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

2.42e-0954717922GO:0007606
GeneOntologyBiologicalProcesssodium ion transmembrane transport

NPPA SLC9A8 SLC5A4 SLC5A5 SLC6A2 SLC9A2 NALCN SCN1A SCN2A SCN5A SCN8A SCN10A SLC13A5 SLC41A1

3.97e-0920817914GO:0035725
GeneOntologyBiologicalProcesssensory perception of smell

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR14A2 OR6C1 OR5H8 OR5H2 OR6T1 OR52B6 OR2AE1

4.39e-0946517920GO:0007608
GeneOntologyBiologicalProcessmonoatomic cation transport

NPPA SLC9A8 CALHM5 SLC2A9 PTGER3 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC2A10 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1

5.09e-09115717932GO:0006812
GeneOntologyBiologicalProcessmetal ion transport

NPPA SLC9A8 PTGER3 SLC30A6 SLC5A4 SLC5A5 CACNG3 CACNG2 SLC6A2 SLC9A2 MS4A2 MS4A1 NALCN KCND1 KCND2 KCND3 SCN1A GLP1R SCN2A ATP2C2 SCN5A SCN8A TMEM37 SCN10A SLC13A5 NIPA2 CACNG5 SLC41A1 PLP1

1.05e-08100017929GO:0030001
GeneOntologyBiologicalProcessorganic anion transport

ACSL6 SLC2A9 HTR6 SLC26A9 SLCO1B3 ATP8B1 TTYH3 SLC43A3 PTGER3 SLC22A7 SLC4A2 SLC2A10 SLC22A9 SLC7A2 MFSD2A SV2A SLC22A10 SLC13A5 SLC16A7

1.24e-0751517919GO:0015711
GeneOntologyBiologicalProcesssodium ion transport

NPPA SLC9A8 SLC5A4 SLC5A5 SLC6A2 SLC9A2 NALCN SCN1A SCN2A SCN5A SCN8A SCN10A SLC13A5 SLC41A1

1.34e-0727517914GO:0006814
GeneOntologyBiologicalProcesstransmission of nerve impulse

CACNG3 CACNG2 KCND2 SCN1A SCN2A SCN5A SCN8A SCN10A CACNG5

5.82e-071121799GO:0019226
GeneOntologyBiologicalProcesslipid translocation

ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3

8.64e-07601797GO:0034204
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3

1.50e-06651797GO:0097035
GeneOntologyBiologicalProcessphospholipid transport

ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3 PLTP

4.02e-061061798GO:0015914
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

GPR3 PDE3B MC1R LGR4 PTGER3 PTGER4 PTGFR GLP1R GPR119 CNR2

6.82e-0619117910GO:0007189
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

GPR3 PDE3B HTR6 MC1R LGR4 PTGER3 PTGER4 PTGFR GLP1R HRH4 GPR119 CNR2

7.96e-0628617912GO:0007188
GeneOntologyBiologicalProcesscardiac muscle cell action potential

KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.07e-05871797GO:0086001
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN5A SCN8A SCN10A

1.41e-05361795GO:0086010
GeneOntologyBiologicalProcesscarboxylic acid transport

ACSL6 HTR6 SLC26A9 SLCO1B3 ATP8B1 TTYH3 SLC43A3 SLC22A7 SLC22A9 SLC7A2 MFSD2A SV2A SLC13A5 SLC16A7

1.46e-0541017914GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

ACSL6 HTR6 SLC26A9 SLCO1B3 ATP8B1 TTYH3 SLC43A3 SLC22A7 SLC22A9 SLC7A2 MFSD2A SV2A SLC13A5 SLC16A7

1.54e-0541217914GO:0015849
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.61e-05621796GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

KCND2 SCN1A SCN2A SCN5A SCN8A SCN10A

1.77e-05631796GO:0019228
GeneOntologyBiologicalProcessxenobiotic transmembrane transport

ABCA3 ATP8B1 ABCA8 ATRAID

1.92e-05191794GO:0006855
GeneOntologyBiologicalProcessmonoatomic anion transport

GPR89B ANO2 SLC26A9 ATP8B1 TTYH3 SLC4A2 SLC5A5 GPR89A ANO3

3.25e-051831799GO:0006820
GeneOntologyBiologicalProcessneurotransmitter receptor transport, postsynaptic endosome to lysosome

CACNG3 CACNG2 CACNG5

3.49e-0581793GO:0098943
GeneOntologyBiologicalProcesslipid transport

ACSL6 ABCA3 ABCA4 XKR9 SLCO1B3 ATP8B1 SLC43A3 ABCA10 ABCA8 SLC22A7 SLC22A9 MFSD2A ABCG1 ANO3 PLTP

3.72e-0550617915GO:0006869
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GPR89B ANO2 SLC26A9 TTYH3 SLC4A2 SLC5A5 GPR89A ANO3

5.84e-051531798GO:0098656
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

CACNG3 CACNG2 CACNG5 PRRT1

6.02e-05251794GO:2000311
GeneOntologyBiologicalProcessaction potential

KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A CNR2

6.75e-052011799GO:0001508
GeneOntologyBiologicalProcessorganic hydroxy compound transport

AQP10 ABCA3 ABCA4 HTR6 SLCO1B3 ATP8B1 PTGER3 ABCA8 SLC6A2 ABCG1 SLC16A7 PLTP

7.20e-0535817912GO:0015850
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

CYP2A7 CYP2A13 UGT1A10

7.37e-05101793GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

CYP2A7 CYP2A13 UGT1A10

7.37e-05101793GO:0009804
GeneOntologyBiologicalProcessthermotaxis

OPN4 RHO

7.49e-0521792GO:0043052
GeneOntologyBiologicalProcesspositive regulation of cholesterol efflux

ABCA3 ABCA8 ABCG1 PLTP

8.23e-05271794GO:0010875
GeneOntologyBiologicalProcessorganophosphate ester transport

ABCA3 ABCA4 XKR9 ATP8B1 MFSD2A ABCG1 ANO3 PLTP

8.73e-051621798GO:0015748
GeneOntologyBiologicalProcesscardiac muscle contraction

NPPA MET KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.08e-041671798GO:0060048
GeneOntologyBiologicalProcessphospholipid translocation

ABCA4 XKR9 ATP8B1 MFSD2A ANO3

1.14e-04551795GO:0045332
GeneOntologyBiologicalProcessactin-mediated cell contraction

PTGER3 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.23e-041271797GO:0070252
GeneOntologyBiologicalProcesslipid localization

ACSL6 ABCA3 ABCA4 XKR9 SLCO1B3 ATP8B1 SLC43A3 ABCA10 ABCA8 SLC22A7 SLC22A9 MFSD2A ABCG1 ANO3 PLTP

1.28e-0456517915GO:0010876
GeneOntologyBiologicalProcesscardiac muscle cell contraction

KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.60e-04931796GO:0086003
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

NPPA PTGER3 CACNG3 CACNG2 MS4A2 MS4A1 NALCN GLP1R ATP2C2 TMEM37 CACNG5 PLP1

1.69e-0439217912GO:0070588
GeneOntologyBiologicalProcesspigment metabolic process

CYP2A13 UGT1A10 TMEM14A MC1R SLCO1B3 ABCB10

1.70e-04941796GO:0042440
GeneOntologyBiologicalProcessneurotransmitter receptor diffusion trapping

CACNG3 CACNG2 CACNG5

1.72e-04131793GO:0099628
GeneOntologyBiologicalProcesspostsynaptic neurotransmitter receptor diffusion trapping

CACNG3 CACNG2 CACNG5

1.72e-04131793GO:0098970
GeneOntologyBiologicalProcessinorganic anion transport

ANO2 SLC26A9 ATP8B1 TTYH3 SLC4A2 SLC5A5 ANO3 MFSD5

1.81e-041801798GO:0015698
GeneOntologyBiologicalProcessdetection of temperature stimulus

OPN4 RHO SCN10A ANO3

1.84e-04331794GO:0016048
GeneOntologyBiologicalProcessmuscle contraction

NPPA PTGER3 PTGER4 MET SSPN KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

2.03e-0440017912GO:0006936
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission

HTR6 PTGER4 CACNG3 CACNG2 NALCN LRRTM2 CACNG5 PRRT1 MUSK

2.07e-042331799GO:0050806
GeneOntologyBiologicalProcessreceptor diffusion trapping

CACNG3 CACNG2 CACNG5

2.18e-04141793GO:0098953
GeneOntologyBiologicalProcesscirculatory system process

NPPA ANGPT1 PTGER3 SLC5A5 SLC2A10 MET SLC7A2 MFSD2A KCND2 KCND3 SCN1A GLP1R SCN2A SCN5A SCN8A SCN10A SLC16A7

2.28e-0473317917GO:0003013
GeneOntologyBiologicalProcessxenobiotic transport

ABCA3 ATP8B1 SLC43A3 ABCA8 ATRAID

2.35e-04641795GO:0042908
GeneOntologyBiologicalProcessbehavior

OPN4 HTR6 MC1R REG1B PTGER3 PTGER4 ARF4 MET MFSD2A IGF2 KCND2 SCN1A GLP1R SCN2A SCN8A SCN10A PRRT1 UNC79 MUSK

2.83e-0489117919GO:0007610
GeneOntologyBiologicalProcessheart contraction

NPPA MET KCND2 KCND3 SCN1A GLP1R SCN2A SCN5A SCN8A SCN10A

2.87e-0429817910GO:0060047
GeneOntologyBiologicalProcessheart process

NPPA MET KCND2 KCND3 SCN1A GLP1R SCN2A SCN5A SCN8A SCN10A

3.82e-0430917910GO:0003015
GeneOntologyBiologicalProcessactin filament-based movement

PTGER3 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

3.86e-041531797GO:0030048
GeneOntologyBiologicalProcessregulation of cAMP-mediated signaling

GPR3 PDE3B PTGER3 PTGER4

3.93e-04401794GO:0043949
GeneOntologyBiologicalProcesspositive regulation of sterol transport

ABCA3 ABCA8 ABCG1 PLTP

3.93e-04401794GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

ABCA3 ABCA8 ABCG1 PLTP

3.93e-04401794GO:0032376
GeneOntologyBiologicalProcessregulation of synaptic transmission, cholinergic

HTR6 NALCN MUSK

4.00e-04171793GO:0032222
GeneOntologyBiologicalProcesscAMP-mediated signaling

GPR3 PDE3B PTGER3 PTGER4 GLP1R

5.23e-04761795GO:0019933
GeneOntologyBiologicalProcessmonocarboxylic acid transport

ACSL6 SLCO1B3 ATP8B1 SLC43A3 SLC22A7 SLC22A9 MFSD2A SLC16A7

5.60e-042131798GO:0015718
GeneOntologyBiologicalProcessstriated muscle contraction

NPPA MET KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

6.33e-042171798GO:0006941
GeneOntologyBiologicalProcessregulation of pH

GPR89B SLC9A8 SLC26A9 SLC4A2 SLC9A2 GPR89A

6.34e-041201796GO:0006885
GeneOntologyBiologicalProcessmembrane depolarization

CACNG2 SCN1A SCN2A SCN5A SCN8A SCN10A

6.62e-041211796GO:0051899
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in thermoception

OPN4 RHO

7.36e-0451792GO:0050960
GeneOntologyBiologicalProcessspongiotrophoblast layer developmental growth

PLAC1 IGF2

7.36e-0451792GO:0090214
GeneOntologyBiologicalProcesssynaptic signaling

NPPA HTR6 PTGER4 CACNG3 CACNG2 SLC6A2 MET NALCN KCND2 SV2A LRRTM2 HRH4 CACNG5 PRRT1 MCTP2 PLP1 MUSK GPR151 CNR2

8.56e-0497617919GO:0099536
GeneOntologyBiologicalProcesschloride transport

ANO2 SLC26A9 ATP8B1 TTYH3 SLC4A2 ANO3

8.89e-041281796GO:0006821
GeneOntologyBiologicalProcessregulation of hormone levels

NPPA PDE3B CYP2D7 UGT1A10 RDH12 PTGER3 PTGER4 SLC5A5 SLC22A9 ABCG1 SIDT2 IGF2 GLP1R EXOC3L1 GPR119

9.49e-0468417915GO:0010817
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC5A5 SLC2A10 SLC7A2 MFSD2A SLC16A7

9.68e-04871795GO:0150104
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

NPPA SLC9A8 PTGER3 SLC9A2 NALCN KCND1 KCND2 KCND3

9.76e-042321798GO:0071805
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

PTGDR PTGER4 PTGFR

1.00e-03231793GO:0071379
GeneOntologyBiologicalProcesspositive regulation of cAMP-mediated signaling

GPR3 PTGER3 PTGER4

1.00e-03231793GO:0043950
GeneOntologyBiologicalProcessvascular transport

SLC5A5 SLC2A10 SLC7A2 MFSD2A SLC16A7

1.02e-03881795GO:0010232
GeneOntologyBiologicalProcessreceptor internalization

ANGPT1 PTGER3 CACNG3 CACNG2 LRRTM2 CACNG5 LMBRD1

1.08e-031821797GO:0031623
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

ANO2 SLC26A9 TTYH3 SLC4A2 SLC5A5 ANO3

1.13e-031341796GO:0098661
GeneOntologyBiologicalProcessamide transport

AQP10 PDE3B SLCO1B3 PTGER3 PTGER4 ABCG1 SIDT2 GLP1R EXOC3L1 PLTP GPR119

1.14e-0342017911GO:0042886
GeneOntologyBiologicalProcessregulation of membrane potential

NPPA CACNG2 MET NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A CNR2

1.23e-0355917913GO:0042391
GeneOntologyBiologicalProcessheme metabolic process

CYP2A13 TMEM14A SLCO1B3 ABCB10

1.24e-03541794GO:0042168
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

HTR6 PTGER4 CACNG3 CACNG2 SLC6A2 MET NALCN KCND2 SV2A LRRTM2 HRH4 CACNG5 PRRT1 MCTP2 PLP1 MUSK GPR151 CNR2

1.27e-0393117918GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

HTR6 PTGER4 CACNG3 CACNG2 SLC6A2 MET NALCN KCND2 SV2A LRRTM2 HRH4 CACNG5 PRRT1 MCTP2 PLP1 MUSK GPR151 CNR2

1.27e-0393117918GO:0007268
GeneOntologyBiologicalProcessregulation of intracellular pH

GPR89B SLC9A8 SLC4A2 SLC9A2 GPR89A

1.37e-03941795GO:0051453
GeneOntologyBiologicalProcesstrans-synaptic signaling

HTR6 PTGER4 CACNG3 CACNG2 SLC6A2 MET NALCN KCND2 SV2A LRRTM2 HRH4 CACNG5 PRRT1 MCTP2 PLP1 MUSK GPR151 CNR2

1.39e-0393917918GO:0099537
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

CACNG3 CACNG2 CACNG5 PRRT1

1.42e-03561794GO:0099601
GeneOntologyBiologicalProcessmembrane repolarization

NPPA KCND2 KCND3 SCN5A

1.42e-03561794GO:0086009
GeneOntologyBiologicalProcessregulation of cholesterol efflux

ABCA3 ABCA8 ABCG1 PLTP

1.42e-03561794GO:0010874
GeneOntologyBiologicalProcessxenobiotic metabolic process

CYP2A7 CYP2A13 CYP2D7 UGT1A10 SLCO1B3 SLC22A7

1.46e-031411796GO:0006805
GeneOntologyBiologicalProcessresponse to prostaglandin D

PTGDR PTGFR

1.53e-0371792GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

PTGDR PTGFR

1.53e-0371792GO:0071799
GeneOntologyBiologicalProcessbundle of His cell action potential

SCN5A SCN10A

1.53e-0371792GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

SCN5A SCN10A

1.53e-0371792GO:0086028
GeneOntologyCellularComponentmonoatomic ion channel complex

GPR89B ANO2 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5

4.07e-0837818317GO:0034702
GeneOntologyCellularComponentsynaptic membrane

ANO2 CACNG3 CACNG2 SLC6A2 MET SSPN KCND1 KCND2 KCND3 SCN1A SCN2A LRRTM2 SCN8A SCN10A CACNG5 PRRT1 PCDH10 SLC16A7 MUSK GPR151

2.12e-0758318320GO:0097060
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN5A SCN8A SCN10A

2.77e-07171835GO:0001518
GeneOntologyCellularComponentbasal part of cell

AQP10 SLC2A9 SLCO1B3 REG1B SLC43A3 ABCA8 SLC22A7 SLC4A2 MET SLC22A9 ATP2C2 SLC22A10 SLC13A5 SLC41A1 SLC16A7

1.28e-0637818315GO:0045178
GeneOntologyCellularComponenttransporter complex

GPR89B ANO2 ATP8B1 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5

1.74e-0655018318GO:1990351
GeneOntologyCellularComponentbasal plasma membrane

AQP10 SLC2A9 SLCO1B3 SLC43A3 ABCA8 SLC22A7 SLC4A2 MET SLC22A9 ATP2C2 SLC22A10 SLC13A5 SLC41A1 SLC16A7

3.05e-0635418314GO:0009925
GeneOntologyCellularComponenttransmembrane transporter complex

GPR89B ANO2 TTYH3 CACNG3 CACNG2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5

3.75e-0652318317GO:1902495
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN5A SCN8A SCN10A

4.87e-06291835GO:0034706
GeneOntologyCellularComponentbasolateral plasma membrane

AQP10 SLC2A9 SLCO1B3 SLC43A3 ABCA8 SLC22A7 SLC4A2 SLC22A9 ATP2C2 SLC22A10 SLC13A5 SLC41A1 SLC16A7

5.19e-0632018313GO:0016323
GeneOntologyCellularComponentpostsynaptic membrane

CACNG3 CACNG2 MET SSPN KCND1 KCND2 KCND3 LRRTM2 SCN8A CACNG5 PRRT1 PCDH10 SLC16A7 MUSK

1.41e-0540518314GO:0045211
GeneOntologyCellularComponentcation channel complex

CACNG3 CACNG2 KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

4.41e-0523518310GO:0034703
GeneOntologyCellularComponentendoplasmic reticulum membrane

ACSL6 CYP2A7 CYP2A13 VMA21 GPAA1 CYP4B1 UGT1A10 TMEM14A HLA-DRB3 DOLK RDH12 RTN3 SLC26A9 TLR7 OR2L13 RHO MFSD2A SPCS3 ABCG1 ZDHHC9 PGAP2 HHAT POFUT2 TM4SF20 LMBRD1 GSG1

6.25e-05129318326GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

ACSL6 CYP2A7 CYP2A13 VMA21 GPAA1 CYP4B1 UGT1A10 TMEM14A HLA-DRB3 DOLK RDH12 RTN3 SLC26A9 TLR7 OR2L13 RHO MFSD2A SPCS3 ABCG1 ZDHHC9 PGAP2 HHAT POFUT2 TM4SF20 LMBRD1 GSG1

6.75e-05129918326GO:0098827
GeneOntologyCellularComponentpostsynaptic specialization membrane

CACNG3 CACNG2 KCND2 KCND3 LRRTM2 SCN8A CACNG5 PRRT1 SLC16A7

7.23e-052011839GO:0099634
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

ACSL6 CYP2A7 CYP2A13 VMA21 GPAA1 CYP4B1 UGT1A10 TMEM14A HLA-DRB3 DOLK RDH12 RTN3 SLC26A9 TLR7 OR2L13 RHO MFSD2A SPCS3 ABCG1 ZDHHC9 PGAP2 HHAT POFUT2 TM4SF20 LMBRD1 GSG1

9.56e-05132718326GO:0042175
GeneOntologyCellularComponentsperm head plasma membrane

OPN4 ADAM21 RHO

1.03e-04111833GO:1990913
GeneOntologyCellularComponentsperm head

OPN4 ADAM21 PCDH11Y RHO

1.30e-04301834GO:0061827
GeneOntologyCellularComponentplasma membrane protein complex

HLA-DRB3 CACNG3 CACNG2 SSPN CD3D MS4A2 KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A CACNG5 TRAV40 PLP1 LILRA4

1.92e-0478518318GO:0098797
GeneOntologyCellularComponentphotoreceptor inner segment membrane

RDH12 RHO

4.52e-0441832GO:0060342
GeneOntologyCellularComponentpostsynaptic density membrane

CACNG3 CACNG2 LRRTM2 SCN8A CACNG5 PRRT1 SLC16A7

4.75e-041571837GO:0098839
GeneOntologyCellularComponentmembrane protein complex

GPR89B ANO2 GPAA1 HLA-DRB3 TTYH3 CACNG3 CACNG2 SPCS3 SSPN CD3D MS4A2 NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A TMEM37 SCN10A GPR89A CACNG5 TRAV40 PLP1 LILRA4

6.28e-04149818326GO:0098796
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

6.74e-04201833GO:0033268
GeneOntologyCellularComponentglutamatergic synapse

ANO2 RTN3 ELMO1 ARF4 CACNG3 CACNG2 LINGO1 KCND2 SV2A SCN2A LRRTM2 SCN8A SCN10A CACNG5 PRRT1 PCDH10 SLC16A7

8.67e-0481718317GO:0098978
GeneOntologyCellularComponentsperm plasma membrane

OPN4 ADAM21 RHO

8.99e-04221833GO:0097524
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN4 ABCA4 RHO

1.48e-03261833GO:0097381
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

2.04e-03291833GO:0043194
GeneOntologyCellularComponentAMPA glutamate receptor complex

CACNG3 CACNG2 CACNG5

2.25e-03301833GO:0032281
GeneOntologyCellularComponentexcitatory synapse

CACNG3 MET LRRTM2 SCN8A SLC16A7

2.52e-031071835GO:0060076
GeneOntologyCellularComponentFc-epsilon receptor I complex

MS4A2 LILRA4

2.64e-0391832GO:0032998
GeneOntologyCellularComponentGolgi membrane

GPR89B SLC9A8 HLA-DRB3 RTN3 SLC26A9 TLR7 RHO ARF4 ABCG1 ZDHHC9 PGAP2 HHAT ATP2C2 GPR89A

4.56e-0372118314GO:0000139
GeneOntologyCellularComponentFc receptor complex

MS4A2 LILRA4

4.75e-03121832GO:0032997
GeneOntologyCellularComponentT-tubule

KCND2 SCN1A SCN2A SCN5A

5.13e-03791834GO:0030315
GeneOntologyCellularComponentsomatodendritic compartment

NPPA OPN4 HTR6 ADAM21 REG1B PTGER3 PTGER4 ARF4 CACNG3 CACNG2 SLC6A2 MET KCND1 KCND2 KCND3 SV2A SCN1A SCN8A HRH4 CNR2

5.56e-03122818320GO:0036477
DomainGPCR_Rhodpsn_7TM

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 GPR75 HRH4 OR5H2 OR6T1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

1.08e-1767017536IPR017452
Domain7tm_1

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 GPR75 HRH4 OR5H2 OR6T1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

1.50e-1767717536PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 GPR75 HRH4 OR5H2 OR6T1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

2.19e-1768517536PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 GPR75 HRH4 OR5H2 OR6T1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

2.88e-1769117536PS50262
DomainGPCR_Rhodpsn

OR8I2 GPR3 OPN4 MRGPRD HTR6 GPR33 OR4C6 OR52L1 MC1R LGR4 TAAR2 OR5A1 OR10C1 PTGDR PTGER3 PTGER4 PTGFR OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 GPR75 HRH4 OR5H2 OR6T1 OR52B6 OR2AE1 GPR119 GPR151 CNR2

3.02e-1769217536IPR000276
DomainMFS

SLC2A9 SLCO1B3 SVOPL SLC22A7 SLC2A10 SLC22A9 MFSD2A SV2A SLC22A10 SLC49A3 SLC16A7 MFSD5

4.01e-1010817512PS50850
DomainMFS_dom

SLC2A9 SLCO1B3 SLC43A3 SVOPL SLC22A7 SLC2A10 SLC22A9 MFSD2A SV2A SLC22A10 SLC49A3 SLC16A7 MFSD5

4.05e-1013417513IPR020846
DomainChannel_four-helix_dom

NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

2.77e-09571759IPR027359
Domain-

NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

2.77e-095717591.20.120.350
DomainNa_channel_asu

SCN1A SCN2A SCN5A SCN8A SCN10A

1.65e-08101755IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN5A SCN8A SCN10A

1.65e-08101755IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN5A SCN8A SCN10A

1.65e-08101755PF06512
DomainOlfact_rcpt

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 OR5H2 OR6T1 OR52B6 OR2AE1

3.26e-0839317518IPR000725
DomainMFS_1

SLC43A3 SVOPL SLC22A7 SLC22A9 MFSD2A SV2A SLC22A10 SLC49A3 SLC16A7

4.23e-08771759PF07690
DomainMFS

SLC43A3 SVOPL SLC22A7 SLC22A9 MFSD2A SV2A SLC22A10 SLC49A3 SLC16A7

4.23e-08771759IPR011701
DomainNa_trans_cytopl

SCN1A SCN2A SCN5A SCN8A

1.10e-0761754PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN5A SCN8A

1.10e-0761754IPR024583
DomainProstanoid_rcpt

PTGDR PTGER3 PTGER4 PTGFR

5.06e-0781754IPR008365
DomainDUF3399

KCND1 KCND2 KCND3

8.09e-0731753PF11879
DomainK_chnl_volt-dep_Kv4

KCND1 KCND2 KCND3

8.09e-0731753IPR003975
DomainShal-type

KCND1 KCND2 KCND3

8.09e-0731753PF11601
DomainShal-type_N

KCND1 KCND2 KCND3

8.09e-0731753IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND1 KCND2 KCND3

8.09e-0731753IPR024587
DomainIon_trans_dom

NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.26e-061141759IPR005821
DomainIon_trans

NALCN KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.26e-061141759PF00520
DomainCD20-like

MS4A12 MS4A10 SSPN MS4A2 MS4A1

1.58e-06221755IPR007237
DomainCD20

MS4A12 MS4A10 SSPN MS4A2 MS4A1

1.58e-06221755PF04103
DomainABC_A

ABCA3 ABCA4 ABCA10 ABCA8

3.48e-06121754IPR026082
DomainABC_tran

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

5.50e-06481756PF00005
DomainABC_TRANSPORTER_2

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

5.50e-06481756PS50893
DomainABC_TRANSPORTER_1

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

6.22e-06491756PS00211
DomainABC_transporter-like

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

7.01e-06501756IPR003439
DomainMFS_sugar_transport-like

SLC2A9 SVOPL SLC2A10 SV2A SLC22A10

2.03e-05361755IPR005828
DomainSugar_tr

SLC2A9 SVOPL SLC2A10 SV2A SLC22A10

2.03e-05361755PF00083
DomainPMP22_Claudin

CLDN14 CACNG3 CACNG2 LIM2 CACNG5

3.44e-05401755PF00822
DomainVDCC_gsu

CACNG3 CACNG2 CACNG5

4.37e-0581753IPR008368
DomainABC_transporter_CS

ABCA3 ABCA4 ABCA10 ABCG1 ABCB10

4.38e-05421755IPR017871
DomainPMP22/EMP/MP20/Claudin

CLDN14 CACNG3 CACNG2 LIM2 CACNG5

6.15e-05451755IPR004031
DomainProstglndn_DP_rcpt

PTGER3 PTGER4

2.60e-0431752IPR001244
DomainMS4A

MS4A10 MS4A2 MS4A1

2.73e-04141753IPR030417
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A7 CYP2A13

5.17e-0441752IPR008067
Domain7TM_GPCR_Srsx

OPN4 HTR6 MC1R TAAR2 RHO CNR2

6.54e-041121756SM01381
DomainThbox_rcpt

PTGDR PTGFR

8.57e-0451752IPR001105
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN5A SCN8A SCN10A

1.58e-03901755IPR000048
DomainAnoct_dimer

ANO2 ANO3

1.78e-0371752PF16178
DomainAnoct_dimer

ANO2 ANO3

1.78e-0371752IPR032394
DomainIQ

SCN1A SCN2A SCN5A SCN8A SCN10A

1.82e-03931755PS50096
DomainK_chnl_volt-dep_Kv

KCND1 KCND2 KCND3

2.00e-03271753IPR003968
DomainClaudin

CLDN14 CACNG3 CACNG2

2.23e-03281753IPR006187
DomainLRRNT

LGR4 TLR7 LINGO1 LRRTM2 LUM

2.30e-03981755IPR000372
DomainLRRNT

LGR4 TLR7 LINGO1 LRRTM2 LUM

2.30e-03981755SM00013
DomainNa/solute_symporter_CS

SLC5A4 SLC5A5

2.36e-0381752IPR018212
DomainRetinal_BS

OPN4 RHO

2.36e-0381752IPR027430
DomainAAA+_ATPase

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

2.38e-031441756IPR003593
DomainAAA

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

2.38e-031441756SM00382
DomainNaH_exchanger

SLC9A8 SLC9A2

3.01e-0391752IPR004709
DomainPMP22_EMP_MP20

LIM2 TMEM37

3.01e-0391752IPR004032
DomainPMP22_2

LIM2 TMEM37

3.01e-0391752PS01222
DomainPMP22_1

LIM2 TMEM37

3.01e-0391752PS01221
DomainSugar_transporter_CS

SLC2A9 SLC2A10 SV2A

3.28e-03321753IPR005829
DomainVG_K_chnl

KCND1 KCND2 KCND3

3.59e-03331753IPR028325
DomainOPSIN

OPN4 RHO

3.74e-03101752PS00238
DomainLRR_5

TLR7 LINGO1

3.74e-03101752PF13306
DomainLRR_5

TLR7 LINGO1

3.74e-03101752IPR026906
DomainAnoctamin

ANO2 ANO3

3.74e-03101752PF04547
DomainAnoctamin

ANO2 ANO3

3.74e-03101752IPR007632
DomainOpsin

OPN4 RHO

4.54e-03111752IPR001760
DomainNA_SOLUT_SYMP_1

SLC5A4 SLC5A5

4.54e-03111752PS00456
DomainCation/H_exchanger_CPA1

SLC9A8 SLC9A2

4.54e-03111752IPR018422
DomainNA_SOLUT_SYMP_2

SLC5A4 SLC5A5

5.42e-03121752PS00457
DomainSSF

SLC5A4 SLC5A5

5.42e-03121752PF00474
DomainNa/solute_symporter

SLC5A4 SLC5A5

5.42e-03121752IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A4 SLC5A5

5.42e-03121752PS50283
DomainLRR_8

LGR4 TLR7 LINGO1 TLR5 LRRTM2 LUM

5.54e-031711756PF13855
DomainLeu-rich_rpt_typical-subtyp

LGR4 TLR7 LINGO1 TLR5 LRRTM2 LUM

6.52e-031771756IPR003591
DomainLRR_TYP

LGR4 TLR7 LINGO1 TLR5 LRRTM2 LUM

6.52e-031771756SM00369
DomainIQ

SCN1A SCN2A SCN5A SCN8A

7.08e-03811754SM00015
DomainNa_H_Exchanger

SLC9A8 SLC9A2

7.38e-03141752PF00999
DomainCation/H_exchanger

SLC9A8 SLC9A2

7.38e-03141752IPR006153
DomainSugar/inositol_transpt

SLC2A9 SLC2A10

7.38e-03141752IPR003663
DomainCyt_P450_E_grp-I

CYP2A7 CYP2A13 CYP4B1

8.60e-03451753IPR002401
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO2 AQP10 SLC9A8 ABCA3 ABCA4 SLC2A9 SLC26A9 SLCO1B3 ATP8B1 TTYH3 ABCA10 ABCA8 SLC22A7 SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC7A2 ABCG1 SLC9A2 ABCB10 NALCN ATP2C2 SLC13A5 NIPA2 SLC41A1 SLC16A7 UNC79 ANO3 PLTP

1.73e-1273613531M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO2 SLC9A8 ABCA3 ABCA4 SLC2A9 SLC26A9 SLCO1B3 ATP8B1 TTYH3 ABCA8 SLC22A7 SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC2A10 ABCG1 SLC9A2 NALCN ATP2C2 SLC13A5 NIPA2 SLC41A1 SLC16A7 UNC79 ANO3 PLTP

2.36e-1068113527MM14985
PathwayREACTOME_SENSORY_PERCEPTION

OR8I2 ANO2 ABCA4 OR4C6 OR52L1 RDH12 OR5A1 OR10C1 TAS2R38 OR10R2 OR2L13 OR6X1 RHO OR8U8 OR12D3 OR52I2 TAS2R16 OR51D1 OR4S1 OR14A2 OR6C1 SCN2A OR5H2 OR6T1 OR52B6 OR2AE1

2.78e-1063613526M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8I2 ANO2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR14A2 OR6C1 OR5H2 OR6T1 OR52B6 OR2AE1

2.77e-0941713520M4072
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC2A9 SLC26A9 SLCO1B3 SLC22A7 SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC7A2 SLC9A2 SLC13A5 SLC41A1 SLC16A7

1.56e-0824913515M5988
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR2L13 OR6X1 OR8U8 OR12D3 OR52I2 OR51D1 OR4S1 OR6C1 OR5H2 OR6T1 OR52B6 OR2AE1

3.21e-0838913518M14091
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC2A9 SLC26A9 SLCO1B3 SLC22A7 SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC9A2 SLC13A5 SLC41A1 SLC16A7

6.51e-0823813514MM15076
PathwayWP_GPCRS_NONODORANT

OPN4 MRGPRD HTR6 MC1R PTGDR PTGER3 PTGER4 PTGFR TAS2R16 GLP1R HRH4 ACKR1 GPR119 CNR2

2.57e-0726613514MM15843
PathwayWP_GPCRS_SMALL_LIGAND

PTGDR PTGER3 PTGER4 PTGFR CNR2

5.80e-07181355MM15858
PathwayWP_SMALL_LIGAND_GPCRS

PTGDR PTGER3 PTGER4 PTGFR CNR2

7.81e-07191355M39728
PathwayREACTOME_PROSTANOID_LIGAND_RECEPTORS

PTGDR PTGER3 PTGER4 PTGFR

9.77e-0791354MM15014
PathwayREACTOME_PROSTANOID_LIGAND_RECEPTORS

PTGDR PTGER3 PTGER4 PTGFR

9.77e-0791354M804
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR3 OPN4 HTR6 GPR33 MC1R PTGDR PTGER3 PTGER4 PTGFR RHO CNR2

1.70e-0618613511MM15994
PathwayWP_GPCRS_ODORANT

GPR89B GPR3 GPR33 LGR4 TAAR2 TAS2R38 RHO GPR75 GPR89A OR5H2

2.63e-0615713510MM15872
PathwayKEGG_ABC_TRANSPORTERS

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

3.61e-06441356M11911
PathwayREACTOME_CARDIAC_CONDUCTION

NPPA KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

4.29e-061301359M27454
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR3 OPN4 HTR6 MC1R PTGDR PTGER3 PTGER4 PTGFR RHO OR12D3 GPR75 CNR2

7.45e-0626013512M39397
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

PTGDR PTGER3 PTGER4 PTGFR

7.47e-06141354MM15012
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

PTGDR PTGER3 PTGER4 PTGFR

1.01e-05151354M10620
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN5A SCN8A SCN10A

1.04e-05311355M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN5A SCN8A SCN10A

1.22e-05321355M27455
PathwayREACTOME_FATTY_ACIDS

CYP2A7 CYP2A13 CYP2D7 CYP4B1

2.22e-05181354MM14841
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

2.92e-0571353M27457
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

2.92e-0571353MM15199
PathwayREACTOME_GPCR_LIGAND_BINDING

OPN4 HTR6 MC1R TAAR2 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR RHO TAS2R16 GLP1R HRH4 ACKR1 CNR2

3.69e-0546313515M507
PathwayREACTOME_GPCR_LIGAND_BINDING

OPN4 HTR6 MC1R TAAR2 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR RHO TAS2R16 GLP1R HRH4 CNR2

6.46e-0543013514MM15160
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OPN4 HTR6 MC1R TAAR2 PTGDR PTGER3 PTGER4 PTGFR RHO HRH4 ACKR1 CNR2

7.80e-0533013512M18334
PathwayREACTOME_MUSCLE_CONTRACTION

NPPA KCND1 KCND2 KCND3 SCN1A SCN2A SCN5A SCN8A SCN10A

1.46e-042031359M5485
PathwayREACTOME_CYP2E1_REACTIONS

CYP2A7 CYP2A13 CYP2D7

1.77e-04121353MM14847
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

HTR6 CACNG3 CACNG2 SLC6A2 SCN1A SCN2A SCN5A SCN8A SCN10A CACNG5 LMBRD1 CNR2

2.11e-0436713512M48346
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

PTGDR PTGER3 PTGER4 PTGFR

2.35e-04321354MM15850
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

HTR6 MC1R TAAR2 PTGDR PTGER3 PTGER4 PTGFR GLP1R HRH4 CNR2

2.87e-0427213510M13380
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OPN4 HTR6 MC1R TAAR2 PTGDR PTGER3 PTGER4 PTGFR RHO HRH4 CNR2

3.58e-0433313511MM14963
PathwayREACTOME_FATTY_ACIDS

CYP2A7 CYP2A13 CYP4B1

3.59e-04151353M27126
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA3 ABCA4 ABCA10 ABCA8 ABCG1 ABCB10

4.61e-041031356M758
PathwayREACTOME_SENSORY_PERCEPTION

ABCA4 RDH12 TAS2R38 OR2L13 RHO TAS2R16 OR51D1 OR14A2

4.84e-041901358MM15687
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC26A9 SLC4A2 SLC5A5 SLC7A2 SLC9A2

5.94e-041081356M823
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA3 ABCA10 ABCG1

6.31e-04181353M524
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A9 SLC5A4 SLC2A10

7.44e-04191353MM14718
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

PDE3B HTR6 MC1R TAAR2 PTGDR PTGER4 GLP1R

7.82e-041571357M4904
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A7 SLC6A2 SLC13A5 SLC41A1 SLC16A7

8.01e-04761355MM15072
PathwayBIOCARTA_EICOSANOID_PATHWAY

PTGER3 PTGER4 PTGFR

8.69e-04201353MM1529
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

ABCA4 RDH12 RHO

8.69e-04201353MM14888
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

PTGDR PTGER3 PTGER4 PTGFR

8.84e-04451354M39355
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A9 SLC5A4 SLC2A10

1.01e-03211353M27058
PathwayKEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING

CACNG3 CACNG2 CACNG5

1.01e-03211353M47950
PathwayKEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING

CACNG3 CACNG2 CACNG5

1.01e-03211353M47949
PathwayREACTOME_SIGNALING_BY_GPCR

PDE3B OPN4 HTR6 MC1R TAAR2 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR RHO TAS2R16 GLP1R HRH4 ACKR1 CNR2

1.10e-0370213516M746
PathwayBIOCARTA_EICOSANOID_PATHWAY

PTGER3 PTGER4 PTGFR

1.16e-03221353M22003
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A7 SLC6A2 SLC13A5 SLC41A1 SLC16A7

1.26e-03841355M27334
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

ABCA4 RDH12 RHO

1.32e-03231353M27174
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 ATP8B1 TTYH3 NALCN ATP2C2 UNC79 ANO3

1.52e-031761357MM15718
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

ABCA3 SLC2A9 SLCO1B3 SLC5A5 SLC6A2 SLC2A10 LMBRD1

1.57e-031771357M27476
PathwayREACTOME_XENOBIOTICS

CYP2A7 CYP2A13 CYP2D7

1.69e-03251353MM14846
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNG3 CACNG2 CACNG5

1.69e-03251353M47948
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 ATP8B1 TTYH3 NALCN ATP2C2 UNC79 ANO3

1.90e-031831357M997
PathwayWP_OMEGA6FATTY_ACIDS_IN_SENESCENCE

PTGDR PTGER3 PTGER4 PTGFR

2.15e-03571354M48332
PathwayWP_NRF2_PATHWAY

SLC2A9 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SERPINA1

2.35e-031411356M39454
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN8A

2.36e-03281353M45519
PathwayREACTOME_HDL_REMODELING

ABCG1 PLTP

2.45e-0381352MM15568
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

HTR6 MC1R TAAR2 PTGDR PTGER4 GLP1R

2.53e-031431356MM15055
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO2 TTYH3 NALCN UNC79 ANO3

2.60e-03991355MM14910
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC2A9 SLCO1B3 SLC5A5 SLC6A2 SLC2A10

2.60e-03991355M27474
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A8 SLC9A2

3.14e-0391352M27337
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A8 SLC9A2

3.14e-0391352MM15079
PathwayREACTOME_OPSINS

OPN4 RHO

3.14e-0391352M6285
PathwayKEGG_RETINOL_METABOLISM

CYP2A7 CYP2A13 UGT1A10 RDH12

3.28e-03641354M9488
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO2 TTYH3 NALCN UNC79 ANO3

3.50e-031061355M27200
PathwayREACTOME_SIGNALING_BY_GPCR

OPN4 HTR6 MC1R TAAR2 TAS2R38 PTGDR PTGER3 PTGER4 PTGFR RHO TAS2R16 GLP1R HRH4 CNR2

3.58e-0364613514MM14962
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP2A7 CYP2A13 CYP2D7 CYP4B1

3.66e-03661354MM14839
PathwayREACTOME_OPSINS

OPN4 RHO

3.90e-03101352MM15063
PathwayREACTOME_HDL_REMODELING

ABCG1 PLTP

3.90e-03101352M27849
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC26A9 SLC4A2 SLC5A5 SLC9A2

3.94e-031091355MM15074
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN5A SCN8A SCN10A

4.86e-109184516382098
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR2L13 OR6X1 OR12D3 OR52I2 OR51D1 OR14A2 OR6C1 OR5H8 OR5H2

4.41e-093401841411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR2L13 OR6X1 OR12D3 OR52I2 OR51D1 OR14A2 OR6C1 OR5H8 OR5H2

4.41e-093401841411802173
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN5A SCN8A SCN10A

4.88e-0913184515123669
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR2L13 OR6X1 OR12D3 OR52I2 OR51D1 OR14A2 OR6C1 OR5H8 OR5H2

4.93e-093431841432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR2L13 OR6X1 OR12D3 OR52I2 OR51D1 OR14A2 OR6C1 OR5H8 OR5H2

5.50e-093461841414611657
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN8A SCN10A

1.13e-086184423652591
Pubmed

Prostanoid receptors: structures, properties, and functions.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184410508233
Pubmed

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184420566843
Pubmed

Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184415834430
Pubmed

The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184411927615
Pubmed

Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184417496729
Pubmed

Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta.

PTGDR PTGER3 PTGER4 PTGFR

5.22e-088184419966781
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNG2 KCND1 KCND2 KCND3 SCN1A SCN5A SCN8A SCN10A CACNG5

6.06e-08139184916985003
Pubmed

Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression.

PTGDR PTGER3 PTGER4 PTGFR

9.36e-089184421460251
Pubmed

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

PTGDR PTGER3 PTGER4 PTGFR

9.36e-089184411782353
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN5A SCN8A

9.36e-089184415746173
Pubmed

Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.

KCND1 KCND2 KCND3

1.46e-073184318371079
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.46e-073184332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.46e-073184328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.46e-073184317928448
Pubmed

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

KCND1 KCND2 KCND3

1.46e-073184310729221
Pubmed

The human olfactory receptor gene family.

OR8I2 OR4C6 OR52L1 OR5A1 OR10C1 OR10R2 OR6X1 OR12D3 OR52I2 OR51D1 OR4S1 OR5H8 OR5H2 OR6T1 OR52B6

2.24e-075411841514983052
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN5A SCN8A

3.63e-0712184430175250
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN8A

5.80e-074184317537961
Pubmed

Potential sites of prostaglandin actions in the periimplantation mouse uterus: differential expression and regulation of prostaglandin receptor genes.

PTGER3 PTGER4 PTGFR

5.80e-07418439116135
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN8A

5.80e-074184335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN8A

5.80e-074184329578003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

5.80e-074184321156207
Pubmed

Isolation of a family of organic anion transporters from human liver and kidney.

SLC22A7 SLC22A9 SLC22A10

5.80e-074184311327718
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

CYP2A13 ABCA3 ABCA4 CYP4B1 SLCO1B3 ABCA8 SLC22A7 ABCG1 ABCB10

9.81e-07193184919343046
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

GPR89B CLDN14 DOLK TLR7 VPREB3 MFSD2A SPCS3 SIDT2 LINGO1 MPZL3 ZDHHC9 ATRAID ATP2C2 GPR89A SLC49A3 TM4SF20 MFSD5 GPN3 GSG1

1.37e-069851841912975309
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN5A SCN8A

1.45e-065184317724025
Pubmed

Genetic determinants of P wave duration and PR segment.

MET KCND3 SCN5A SCN10A

1.71e-0617184424850809
Pubmed

Prostanoid receptors in anagen human hair follicles.

PTGDR PTGER3 PTGER4

2.88e-066184318005048
Pubmed

Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor.

PTGER3 PTGER4 PTGFR

2.88e-066184315983244
Pubmed

Chromosomal localization of the human prostanoid receptor gene family.

PTGER3 PTGER4 PTGFR

2.88e-06618437759114
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

5.02e-067184325818041
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

5.02e-067184315272007
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

GPR89B CLDN14 DOLK TLR7 MFSD2A SIDT2 LINGO1 ZDHHC9 GPR89A SLC49A3 TM4SF20 MFSD5

6.98e-064601841220562862
Pubmed

Brugada Syndrome

KCND2 KCND3 SCN5A SCN10A

7.42e-0624184420301690
Pubmed

Calcium channel gamma subunits: a functionally diverse protein family.

CACNG3 CACNG2 CACNG5

8.00e-068184317652770
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

1.20e-059184317884088
Pubmed

A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.

CACNG3 CACNG2 CACNG5

1.20e-059184311170751
Pubmed

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis.

PTGDR PTGER3 PTGER4

1.20e-059184331688905
Pubmed

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.

PTGDR PTGER3 PTGER4 PTGFR

1.21e-0527184423624557
Pubmed

Common variants associated with general and MMR vaccine-related febrile seizures.

SCN1A SCN2A ANO3

1.70e-0510184325344690
Pubmed

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development.

NPPA KCND2 SCN5A SCN10A

1.87e-0530184439366945
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PLAC1 RTN3 SLC43A3 ADA2 MFSD2A SIDT2 IGF2 METTL9 SV2A MFSD5 GSG1

2.03e-054301841116303743
Pubmed

Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts.

PTGDR PTGER3 PTGER4 PTGFR

2.75e-0533184439002541
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN5A SCN10A

2.78e-052184224642470
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.78e-052184237901435
Pubmed

Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.

TLR7 TLR5

2.78e-052184224447081
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.78e-052184226410685
Pubmed

Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans.

TAS2R38 TAS2R16

2.78e-052184218524836
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

2.78e-052184210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

2.78e-052184219694741
Pubmed

Role of EP3 and EP4 prostaglandin receptors in reorganization of the cytoskeleton in mature human osteoclasts.

PTGER3 PTGER4

2.78e-052184215290741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

2.78e-052184235348308
Pubmed

Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis.

CD27 TLR5

2.78e-052184215685542
Pubmed

Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis.

OPN4 RHO

2.78e-052184231924821
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN5A SCN10A

2.78e-052184215047701
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

2.78e-052184215760941
Pubmed

Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice.

ABCA4 RDH12

2.78e-052184217032653
Pubmed

TARP redundancy is critical for maintaining AMPA receptor function.

CACNG3 CACNG2

2.78e-052184218753375
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

2.78e-05218421317301
Pubmed

Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin.

TAS2R38 TAS2R16

2.78e-052184217250611
Pubmed

Mechanism of prostaglandin (PG)E2-induced prolactin expression in human T cells: cooperation of two PGE2 receptor subtypes, E-prostanoid (EP) 3 and EP4, via calcium- and cyclic adenosine 5'-monophosphate-mediated signaling pathways.

PTGER3 PTGER4

2.78e-052184215528329
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

2.78e-052184231439038
Pubmed

Significance of divergent expression of prostaglandin EP4 and EP3 receptors in human prostate cancer.

PTGER3 PTGER4

2.78e-052184223364535
Pubmed

GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.

GPR89B GPR89A

2.78e-052184222572823
Pubmed

Expression of CYP2A genes in human liver and extrahepatic tissues.

CYP2A7 CYP2A13

2.78e-052184210353262
Pubmed

Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications.

CACNG3 CACNG2

2.78e-052184210221464
Pubmed

SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+.

SLC26A9 SLC9A2

2.78e-052184215800055
Pubmed

Differential regulation of the aggressive phenotype of inflammatory breast cancer cells by prostanoid receptors EP3 and EP4.

PTGER3 PTGER4

2.78e-052184220503412
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

2.78e-052184231943325
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

2.78e-052184215249644
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

2.78e-052184215563876
Pubmed

Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation.

PTGER3 PTGER4

2.78e-052184221311040
Pubmed

A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells.

TAS2R38 GLP1R

2.78e-052184227208775
Pubmed

S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation.

KCND1 KCND2

2.78e-052184224675763
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

2.78e-052184226196737
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

2.78e-052184210942109
Pubmed

The deleterious role of the prostaglandin E2 EP3 receptor in angiotensin II hypertension.

PTGER3 PTGER4

2.78e-052184232142358
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

2.78e-052184218601978
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN5A SCN10A

2.78e-052184224998131
Pubmed

GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

GPR89B GPR89A

2.78e-052184218794847
Pubmed

Signaling of Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice.

PTGER3 PTGER4

2.78e-052184227711210
Pubmed

Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors.

PTGER3 PTGER4

2.78e-052184222615395
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

2.78e-052184219465131
Pubmed

Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes.

SLC22A7 SLC22A9

2.78e-052184229906129
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

2.78e-052184216847056
Pubmed

A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma.

MC1R MET

2.78e-052184224975581
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN5A SCN10A

2.78e-052184224360055
Pubmed

Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.

MS4A2 MS4A1

2.78e-05218422448768
Pubmed

Analysis of the arrhythmogenic substrate in human heart failure.

KCND3 SCN5A

2.78e-052184223036686
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

2.78e-052184230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

2.78e-052184223735284
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN5A SCN10A

2.78e-052184232330377
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

2.78e-052184229649454
InteractionSCN11A interactions

NALCN SCN1A SCN5A SCN8A SCN10A

8.61e-08151615int:SCN11A
InteractionTSPAN15 interactions

GPAA1 LGR4 RDH12 RTN3 SLC43A3 SLC4A2 SLC5A4 SLC22A9 SLC7A2 ZDHHC9 GPR89A GPR151

2.34e-0627616112int:TSPAN15
InteractionCREB3L1 interactions

AQP10 TMEM14A DOLK MS4A1 PGAP2 TMEM19 TMEM239 PLP1 MFSD5 GPR151

6.36e-0620616110int:CREB3L1
InteractionFPR2 interactions

GPAA1 DOLK TTYH3 SLC30A6 SLC7A2 GPR89A NIPA2 MFSD5

1.54e-051381618int:FPR2
InteractionFAM241A interactions

ST7 RTN3 SVOPL SLC4A2 LINGO1 CD27 PLP1

1.78e-051021617int:FAM241A
InteractionLRRTM2 interactions

PDE3B ST7 LGR4 LRRTM2

2.11e-05211614int:LRRTM2
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

2.72e-0581613int:SCN4B
InteractionSCN5A interactions

NALCN SCN1A SCN5A SCN8A SCN10A

3.58e-05471615int:SCN5A
InteractionCACNA1D interactions

NALCN SCN1A SCN5A SCN10A

3.68e-05241614int:CACNA1D
InteractionSSMEM1 interactions

AQP10 TMEM14A PGAP2 SLC41A1 TMEM239 MFSD5 GPR151

4.10e-051161617int:SSMEM1
InteractionKCNIP1 interactions

KCND1 KCND2 KCND3 ATRAID

4.35e-05251614int:KCNIP1
InteractionGJA8 interactions

DOLK TTYH3 SLC7A2 PGAP2 SLC13A5 TMEM239 PLP1 GPR151

4.45e-051601618int:GJA8
InteractionGPR21 interactions

ST7 LGR4 SLC4A2 SIDT2 ZDHHC9 GPR89A

4.69e-05811616int:GPR21
InteractionENTREP1 interactions

PDE3B ABCA3 ST7 LGR4 TTYH3 SIDT2

6.57e-05861616int:ENTREP1
InteractionSCN10A interactions

SCN1A SCN5A SCN10A

7.88e-05111613int:SCN10A
InteractionSCN1A interactions

NALCN SCN1A SCN5A SCN10A

7.98e-05291614int:SCN1A
InteractionCLGN interactions

GALNS ST7 TTYH3 SLC4A2 MET SLC22A9 CD3D PLTP CNR2

1.18e-042351619int:CLGN
InteractionYIPF3 interactions

GPAA1 SLC5A4 SLC5A5 SLC7A2 SIDT2 GPR89A NIPA2 MFSD5

1.28e-041861618int:YIPF3
InteractionCREB3 interactions

TMEM14A DOLK MS4A1 ZDHHC9 SLC49A3 TMEM19 PLP1 MFSD5 PLTP

1.34e-042391619int:CREB3
InteractionSCN4A interactions

GPAA1 ST7 SIDT2 SCN8A GPR89A MFSD5

1.36e-04981616int:SCN4A
InteractionTTYH1 interactions

PDE3B ABCA3 GPAA1 HTR6 ST7 RDH12 SLC4A2 ABCB10 ZDHHC9 GPR89A

1.54e-0430016110int:TTYH1
InteractionNALCN interactions

NALCN SCN1A SCN5A

1.71e-04141613int:NALCN
InteractionTMEM63A interactions

GPR89B DOLK SLC4A2 SIDT2 ZDHHC9 MFSD5

1.79e-041031616int:TMEM63A
InteractionCYP2A7 interactions

CYP2A7 CYP2A13

1.89e-0431612int:CYP2A7
InteractionGPR42 interactions

MS4A1 SLC41A1 TMEM19 TMEM239 PLP1 MFSD5

2.69e-041111616int:GPR42
InteractionNIPAL1 interactions

ST7 SLC30A6 SLC7A2 GPR89A NIPA2 MFSD5

3.10e-041141616int:NIPAL1
InteractionKASH5 interactions

SLC5A4 MS4A1 PGAP2 SLC41A1 TMEM19 MFSD5

3.10e-041141616int:KASH5
InteractionCHRNA9 interactions

PDE3B ST7 SLC30A6 METTL9 ZDHHC9

3.16e-04741615int:CHRNA9
InteractionAQP6 interactions

VMA21 TMEM14A ABCG1 MS4A1 SLC41A1 TMEM19 TMEM239 PLP1 MFSD5 GPR151

3.31e-0433016110int:AQP6
InteractionCRELD1 interactions

GPAA1 ST7 DOLK PTGER3 SLC4A2 CD27 GPR89A

3.42e-041631617int:CRELD1
Cytoband17q24

ABCA10 ABCA8 CACNG5

7.44e-0610184317q24
CytobandEnsembl 112 genes in cytogenetic band chr11q12

OR8I2 MS4A12 OR5A1 SLC43A3 MS4A10 SLC22A9 MS4A2 MS4A1 SLC22A10

1.19e-053451849chr11q12
Cytoband7q31

MET TAS2R16 KCND2

1.73e-042718437q31
CytobandEnsembl 112 genes in cytogenetic band chr7q31

SPAM1 ST7 MET TAS2R16 KCND2

2.64e-041401845chr7q31
Cytoband11q11

OR4C6 SLC43A3 OR8U8

9.02e-0447184311q11
GeneFamilySolute carriers

SLC9A8 SLC2A9 SLC26A9 SLCO1B3 SLC43A3 SLC22A7 SLC4A2 SLC30A6 SLC5A4 SLC5A5 SLC6A2 SLC2A10 SLC22A9 SLC7A2 SLC9A2 SLC22A10 SLC13A5 SLC49A3 SLC41A1 SLC16A7

2.19e-1139513820752
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN5A SCN8A SCN10A

2.96e-09913851203
GeneFamilyProstaglandin (prostanoid) receptors

PTGDR PTGER3 PTGER4 PTGFR

3.97e-0791384207
GeneFamilyG protein-coupled receptors, Class A orphans

GPR3 MRGPRD GPR33 LGR4 GPR75 GPR119 GPR151

2.18e-06781387262
GeneFamilyATP binding cassette subfamily A

ABCA3 ABCA4 ABCA10 ABCA8

3.07e-06141384805
GeneFamilyCD molecules|Membrane spanning 4-domains

MS4A12 MS4A10 MS4A2 MS4A1

9.15e-06181384958
GeneFamilyCalcium voltage-gated channel subunits

CACNG3 CACNG2 CACNG5

9.95e-04261383253
GeneFamilyCytochrome P450 family 2

CYP2A7 CYP2A13 CYP2D7

2.38e-033513831001
GeneFamilyCD molecules|Toll like receptors

TLR7 TLR5

2.50e-03101382948
GeneFamilyAnoctamins

ANO2 ANO3

2.50e-03101382865
GeneFamilyOpsin receptors

OPN4 RHO

3.04e-03111382215
GeneFamilyPotassium voltage-gated channels

KCND1 KCND2 KCND3

3.50e-03401383274
GeneFamilyNon-clustered protocadherins

PCDH11Y PCDH10

3.63e-0312138221
GeneFamilyOlfactory receptors, family 52

OR52L1 OR52I2 OR52B6

6.20e-03491383165
GeneFamilyOlfactory receptors, family 6

OR6X1 OR6C1 OR6T1

6.94e-03511383153
GeneFamilySulfatases

GALNS ARSI

8.17e-03181382410
CoexpressionSHEN_SMARCA2_TARGETS_DN

GPR3 ANO2 NPPA CYP2D7 HTR6 RHO CACNG3 TAS2R16 GLP1R SCN2A GPR75 LILRA4

2.54e-0632218012M1676
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA4 SLC5A4 MET SLC22A9 LINGO1 KCND3 SLC22A10 PCDH10 ANO3

5.86e-0818118196e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

CALHM5 PTGDR PTGER3 PTGFR ARSI SVOPL IGF2 LUM

1.80e-0714918183980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PDE3B SLC2A9 ABCG1 IGF2 INTS2 TMEM37 ANTXR1 TM4SF20

3.26e-0716118182fe77af3b41e6eacb707a64feea18f9991618173
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALHM5 ANGPT1 PI15 ABCA8 SLC5A4 NALCN LUM PCDH10

5.40e-071721818ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALHM5 ANGPT1 PI15 ABCA8 SLC5A4 NALCN LUM PCDH10

5.40e-0717218181ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTGDR ABCA10 ABCA8 NALCN KCND2 ANTXR1 ANO3 MUSK

6.15e-071751818795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTGFR IGF2 CD27 TMEM37 SLC49A3 LUM MUSK

7.28e-07123181764a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 LGR4 COLCA1 PTGER3 PI15 ABCA10 SCN2A SLC16A7

8.62e-0718318182f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CALHM5 ABCA4 PTGDR PTGFR SLC7A2 IGF2 LUM MUSK

8.98e-071841818235890e8b424f4386b6ea52d173d20a00898df73
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 SLC26A9 MET MFSD2A MPZL3 SCN1A ATP2C2 MCTP2

9.74e-071861818acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCA3 PTGFR SLC7A2 MFSD2A KCND3 SCN1A ATP2C2 MCTP2

1.06e-061881818ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 SPCS3 ABCG1 TM9SF2 LUM PLP1

1.10e-0618918186dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 SPCS3 ABCG1 TM9SF2 LUM PLP1

1.10e-061891818875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 SPCS3 ABCG1 TM9SF2 LUM PLP1

1.10e-0618918183ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 SPCS3 ABCG1 TM9SF2 LUM PLP1

1.10e-06189181897ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTGDR ABCA10 ABCA8 NALCN KCND2 KCND3 ANTXR1 LUM

1.34e-061941818c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B ANGPT1 COLCA1 PTGER3 SLC9A2 METTL9 SCN2A SLC16A7

1.39e-0619518183f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTGDR ABCA10 ABCA8 NALCN KCND2 KCND3 ANTXR1 LUM

1.39e-0619518183c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPT1 PI15 ABCA8 SLC7A2 SSPN IGF2 ANTXR1 LUM

1.62e-0619918189b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPT1 PI15 ABCA8 SLC7A2 SSPN IGF2 ANTXR1 LUM

1.62e-061991818251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPT1 PI15 ABCA8 SLC7A2 SSPN IGF2 ANTXR1 LUM

1.62e-061991818117f4f43b6c06dda553799b1063e827bce697370
ToppCell-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CLDN14 MS4A1 CD27 SCN5A LUM MUSK CNR2

5.37e-061661817bc9323de1373fdc0357e6bb46874f6c4787443a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PI15 ABCA10 ABCA8 NALCN KCND2 ANTXR1 ANO3

5.81e-0616818174b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

LGR4 VPREB3 ABCA10 SSPN MS4A1 HHAT SCN2A

7.05e-0617318173a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4B1 PTGER3 CACNG2 KCND2 KCND3 TLR5 LUM

7.05e-06173181711e95a60b5f6f07f27154a23203bac431e7528c6
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 UGT1A10 SLC22A7 MFSD2A IGF2 TMEM37 TMEM19

7.59e-061751817076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 UGT1A10 SLC22A7 MFSD2A IGF2 TMEM37 TMEM19

7.59e-061751817445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA4 SLC5A4 MET SLC22A9 KCND3 SLC22A10 ANO3

8.49e-0617818175522b179c2e7dd707de01e2df10556349d0382a6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B ZPLD1 PTGER3 SVOPL SLC7A2 SLC9A2 SCN2A

8.80e-061791817d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA4 SLC5A4 MET SLC22A9 KCND3 SLC22A10 ANO3

9.13e-0618018172ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PI15 ARSI ABCA8 KCND2 LUM PLP1 PLTP

1.05e-0518418174a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA10 ABCA8 NALCN KCND2 KCND3 ANTXR1 ANO3

1.05e-051841817e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.05e-051841817369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CLDN14 VPREB3 SSPN CD3D MS4A1 CD27 CNR2

1.09e-05185181710f7e5daf8e95dda9453212e84b64874f4e0d7ab
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PDE3B LGR4 PTGFR ABCA10 ABCA8 KCND2 ANTXR1

1.17e-0518718174ea486991f66c29728d127171a07b81404ec0b78
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 PI15 ANTXR1 HRH4 LUM ANO3 PLTP

1.17e-0518718170f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 PI15 ANTXR1 HRH4 LUM ANO3 PLTP

1.17e-05187181776c957b2976d38adb45e07bcf96c689442e1fc20
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 PI15 ANTXR1 HRH4 LUM ANO3 PLTP

1.17e-05187181790a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYP2A13 ZPLD1 PTGFR MET SERPINA1 SLC9A2 ATP2C2

1.21e-05188181707705bed928683470a52c8ccfa40ffb9a0971318
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN ANTXR1 LUM ANO3

1.25e-05189181771397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN ANTXR1 LUM ANO3

1.25e-0518918174eea4759520c312bd17a681034d8074e47093d2b
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.30e-05190181727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN ANTXR1 LUM ANO3

1.34e-051911817a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 ABCA8 SSPN IGF2 ANTXR1 LUM PLP1

1.34e-0519118175271198116343c07202649889057e5774d7fdde3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ANGPT1 LGR4 PI15 ABCA8 SSPN PLP1 PLTP

1.34e-05191181706107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.34e-051911817276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN ANTXR1 LUM ANO3

1.34e-0519118178f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN LUM PCDH10 ANO3

1.39e-051921817bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 ABCA10 ABCA8 NALCN LUM PCDH10 ANO3

1.39e-0519218170ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.39e-05192181758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 SLC26A9 PTGFR MET SLC7A2 MFSD2A SCN1A

1.43e-051931817f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC3 CACNG2 KCND2 SCN1A SCN2A SCN8A ACKR1

1.43e-0519318175fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 SLC26A9 PTGFR MET SLC7A2 MFSD2A SCN1A

1.43e-051931817fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.43e-051931817738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 ARF4 TM9SF2 LUM PLP1

1.48e-0519418172224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 ARF4 TM9SF2 LUM PLP1

1.48e-05194181750c5fc349533281a426bc7227a8ea9eca8d11985
ToppCellfacs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 ARF4 TM9SF2 LUM PLP1

1.48e-0519418171662b110f84584e75150df0ac970e7df82f26e7e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZPLD1 ATP8B1 SLC7A2 MFSD2A SLC9A2 SCN2A VWA5B1

1.48e-0519418174579b4a44f7c731553a284843c296866027d7c0e
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

PDE3B LGR4 ABCA10 ABCA8 ANTXR1 LUM MUSK

1.48e-051941817014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA10 ABCA8 SSPN IGF2 LUM PLP1 PLTP

1.48e-05194181735b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B TLR7 ELMO1 ARF4 TM9SF2 LUM PLP1

1.48e-051941817b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZPLD1 ATP8B1 SLC7A2 MFSD2A SLC9A2 SCN2A VWA5B1

1.53e-0519518173d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 COLCA1 PTGER3 ABCA10 SLC6A2 SCN2A SLC16A7

1.53e-051951817a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell(7)_MNP-(7)_Macrophage|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

VPREB3 CD3D MS4A1 CD27 TMEM37 PLTP CNR2

1.59e-05196181771ec157163278ad259c190051926bf41e4ecef46
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.69e-0519818172e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTN3 TTC3 KCND2 SCN1A SCN2A SCN8A UNC79

1.69e-051981817c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTN3 TTC3 KCND2 SCN1A SCN2A SCN8A UNC79

1.69e-0519818176d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 SLC26A9 PTGFR MET MFSD2A SCN1A ATP2C2

1.69e-051981817f948391296c261c473d339069a6d0f20ccd6f38f
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA3 SLC26A9 MET SLC7A2 MFSD2A ZDHHC9 ATP2C2

1.69e-051981817de5748c2b66ecc432974cf095ecd241369579f7c
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 ST7 PTGFR MET MFSD2A SCN1A ATP2C2

1.75e-0519918175f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PI15 SLC6A2 SSPN KCND2 ANTXR1 LUM PLP1

1.75e-05199181795d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA3 CYP4B1 SLC26A9 MET MFSD2A SERPINA1 SCN1A

1.81e-052001817acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA3 CYP4B1 SLC26A9 MET MFSD2A SERPINA1 SCN1A

1.81e-052001817ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCelldistal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANGPT1 ARSI ABCA8 SSPN PGAP2 LUM PLTP

1.81e-05200181720112be28f80baffad92641c9cfd7c3718967dbb
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

ABCA10 ABCA8 SSPN SCN2A LUM PLP1 PLTP

1.81e-0520018179996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CALHM5 PTGER3 ABCA8 SSPN IGF2 ANTXR1 LUM

1.81e-052001817ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCellParenchymal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 CYP4B1 COLCA1 MET MFSD2A SERPINA1 ATP2C2

1.81e-05200181716828c6a2be66bbbd805453325d6da719f2dea1b
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA3 CYP4B1 SLC26A9 MET MFSD2A SERPINA1 SCN1A

1.81e-052001817eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellnormal_Lung-Fibroblasts-COL14A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

ABCA10 ABCA8 SSPN IGF2 ANTXR1 LUM PLTP

1.81e-052001817ee3d06865a6300e1279edf6664320b71647f5efb
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MRGPRD PTGFR IGF2 LUM PLTP MUSK

2.54e-051421816f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPTE2P1 ANO2 OR5A1 ABCA8 SCN1A ANO3

3.33e-051491816c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPTE2P1 ANO2 OR5A1 ABCA8 SCN1A ANO3

3.33e-051491816a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT1 PTGER3 PCNX4 SCN2A SLC49A3 VWA5B1

3.45e-05150181687968ce885a4959616f0321f58517fe8029ba1b1
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 NUP210L TLR5 LUM MUSK

3.69e-05921815926e02725a03d8473eda25d4aef63e34a6566224
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 NUP210L TLR5 LUM MUSK

3.69e-05921815d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

PDE3B SLC2A9 TTYH3 ADA2 ABCG1 TM4SF20

4.15e-05155181615bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|390C / Donor, Lineage, Cell class and subclass (all cells)

ACSL6 PDE3B CD3D MPZL3 CD27 SLC13A5

4.62e-051581816ad0e2371c0bc6e53d22518aa3a401cddcde3759f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CACNG3 MET SPCS3 LINGO1 SCN2A VWA5B1

5.13e-051611816ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellInfluenza_Severe-B_memory|World / Disease group and Cell class

VPREB3 TMEM269 SSPN MS4A1 CD27 SCN2A

5.31e-05162181621eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCellInfluenza_Severe-B_memory|Influenza_Severe / Disease group and Cell class

VPREB3 TMEM269 SSPN MS4A1 CD27 SCN2A

5.88e-05165181651172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PI15 SLC2A10 IGF2 KCND2 LUM PCDH10

5.88e-0516518164e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ANO2 CALHM5 ABCA10 ABCA8 IGF2 LRRTM2

6.08e-051661816f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 RHO SLC2A10 MS4A1 KCND2 KCND3

6.28e-051671816e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLCO1B3 PI15 IGF2 KCND2 LUM PCDH10

6.28e-051671816fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTGDR SLC7A2 IGF2 TMEM37 LUM PLTP

6.49e-0516818169930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

ABCA3 OR2L13 SVOPL SLC4A2 MS4A2 SV2A

6.49e-05168181645ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGER3 PTGFR OR6X1 CD3D SCN5A VWA5B1

6.49e-0516818160a7f81266576409560396356d16989e944865844
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CLDN14 ABCA3 MC1R PTGER3 INTS2 ANTXR1

6.71e-0516918160425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CLDN14 ABCA3 MC1R PTGER3 INTS2 ANTXR1

6.71e-051691816fec669968a77060bd77ee8695034e35a642c984f
ToppCell-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CACNG2 CD3D MS4A1 CD27 LUM LILRA4

6.93e-051701816601630644f09133ee4c5e64499460b55cf3e80a0
Drugverapamil

NPPA CYP2A13 ABCA3 ABCA4 ATP8B1 ABCA10 ABCA8 CACNG3 CACNG2 ABCG1 ABCB10 KCND1 KCND2 KCND3 ATP2C2 SCN5A TMEM37 SCN10A CACNG5 MUSK

2.49e-0949018120CID000002520
Druglamotrigine

UGT1A10 SLC43A3 CACNG3 CACNG2 SCN2A SCN5A TMEM37 SCN10A CACNG5

3.82e-071161819CID000003878
DrugAlprostadil

NPPA PTGDR PTGER3 PTGER4 PTGFR

7.09e-07221815ctd:D000527
Drugbepridil

CACNG3 CACNG2 KCND3 ATP2C2 SCN5A TMEM37 SCN10A SLC13A5 CACNG5

7.70e-071261819CID000002351
Drugfelodipine

CYP2A7 NPPA CYP2A13 PDE3B CYP2D7 CYP4B1 CACNG3 CACNG2 TMEM37 CACNG5

1.05e-0616918110CID000003333
Drugsodium

GPR89B NPPA SLC9A8 SLC2A9 SLC26A9 SLCO1B3 SLC43A3 PTGDR SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC2A10 MET SLC7A2 SLC9A2 KCND2 KCND3 SCN2A ATP2C2 SCN5A SCN10A SLC13A5

1.85e-0694418123CID000000923
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A SCN10A

1.97e-0641813ctd:C501880
DrugZK118182

PTGDR PTGER3 PTGER4 PTGFR

2.61e-06131814CID005311208
DrugMB28767

PTGDR PTGER3 PTGER4 PTGFR

2.61e-06131814CID005311223
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; HL60; HT_HG-U133A

NPPA RHO SSPN ABCG1 SLC9A2 SV2A GPR75 SCN5A GSG1 LILRA4

4.59e-06199181103095_UP
DrugZK110841

PTGDR PTGER3 PTGER4 PTGFR

4.92e-06151814CID005311503
DrugAH13205

PTGDR PTGER3 PTGER4 PTGFR

4.92e-06151814CID000132836
Drugbumetanide

NPPA SLC9A8 SLC22A7 SLC4A2 SLC5A4 SLC5A5 SLC6A2 SLC9A2 SCN2A SLC13A5

7.08e-0620918110CID000002471
DrugProbenecid

SLC2A9 SLCO1B3 TAS2R38 ABCA8 SLC22A9 TAS2R16

7.38e-06591816ctd:D011339
Drugnilvadipine

NPPA RHO CACNG3 CACNG2 TMEM37 CACNG5

8.15e-06601816CID000004494
DrugAC1L9NBR

ANO2 MC1R TAAR2 RHO HRH4 ANO3 CNR2

8.86e-06921817CID000449625
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN8A SCN10A

9.71e-0661813ctd:C475726
Drugphenytoin

CYP2A13 CYP2D7 CYP4B1 CACNG3 CACNG2 SCN2A SCN5A TMEM37 SCN10A CACNG5

1.07e-0521918110CID000001775
DrugD-myo-inositol-1,4,5-triphosphate

NPPA PTGDR PTGER3 PTGER4 PTGFR RHO CACNG3 CACNG2 CD3D MS4A2 MS4A1 GPR75 ATP2C2 TMEM37 HRH4 CACNG5

1.32e-0556818116CID000000806
DrugBW245C

PTGDR PTGER3 PTGER4 PTGFR MUSK

1.79e-05411815CID000119304
Drugforskolin from Coleus forskohlii

NPPA AQP10 PDE3B MRGPRD HTR6 MC1R SLC26A9 PTGER3 PTGER4 PTGFR SLC4A2 SLC5A5 SLC2A10 SPCS3 SLC9A2 IGF2 KCND2 GLP1R SCN10A HRH4 MUSK CNR2

1.91e-05101318122CID000003413
Drugflecainide

CYP2D7 KCND1 KCND2 KCND3 SCN5A SCN10A

2.17e-05711816CID000003355
Drugpyraclofos

CACNG3 CACNG2 KCND1 KCND2 KCND3 SCN2A SCN5A

2.24e-051061817CID000093460
DrugCAS 298-57-7

CYP2D7 CACNG3 CACNG2 TMEM37 HRH4 CACNG5

2.54e-05731816CID000002761
Drugfexofenadine

CYP4B1 SLCO1B3 SLC22A7 SCN5A HRH4 QARS1

2.54e-05731816CID000003348
DrugCocaine

SLC6A2 SCN5A SCN10A

2.69e-0581813DB00907
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN8A SCN10A

2.69e-0581813ctd:C489827
DrugLY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A

ANO2 SLC2A9 PTGER3 SLC22A7 SLC5A4 SV2A GLP1R SCN8A SCN10A

2.73e-0519518195576_UP
DrugDipyridamole [58-32-2]; Up 200; 8uM; PC3; HT_HG-U133A

PDE3B SLC2A9 ABCG1 IGF2 HHAT GPR75 ATP2C2 MCTP2 SLC16A7

2.84e-0519618194656_UP
Drugestrone sulfate

SLCO1B3 ABCA8 SLC22A7 SLC22A9

3.04e-05231814ctd:C017296
Drug(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A

PDE3B ST7 ATP8B1 SLC5A5 HHAT ATP2C2 SCN10A TMEM19 CNR2

3.07e-0519818195444_DN
Drugamiodarone

CYP2D7 PTGDR SLC5A5 SERPINA1 KCND2 KCND3 SCN5A SCN10A

4.36e-051601818CID000002156
Drughalothane

CYP2A7 CYP2A13 CYP2D7 CYP4B1 RHO CACNG3 CACNG2 ATP2C2 TMEM37 CACNG5 MUSK

4.53e-0531418111CID000003562
Drug2-hydroxydesipramine

CYP2D7 SLC5A5 SLC6A2

5.69e-05101813CID000121249
DrugBP-9,10-oxide

CYP2A7 CYP2A13 CYP2D7 CYP4B1

5.88e-05271814CID000037456
DrugBrn 4136738

CYP2A7 CYP2A13 CYP2D7 CYP4B1

5.88e-05271814CID000050331
DrugC14845

CYP2A7 CYP2A13 CYP2D7 CYP4B1

5.88e-05271814CID011954064
DrugHexylcaine

SCN5A SCN10A

6.29e-0521812DB00473
DrugPhenytoin

SCN1A SCN5A

6.29e-0521812DB00252
DrugHeymann Nephritis Antigenic Complex

PTGER3 PTGER4

6.29e-0521812ctd:D026541
Drug4-((diethylamino)sulfonyl)benzoic acid

TAS2R38 TAS2R16

6.29e-0521812ctd:C047832
Drug9-OH-BaP-4,5-oxide

CYP2A7 CYP2A13 CYP2D7 CYP4B1

6.81e-05281814CID000115064
Drugsulfinpyrazone

ABCA3 UGT1A10 SLCO1B3 SLC22A7 SLC22A9 SLC16A7

6.88e-05871816CID000005342
Drugmephenytoin

CYP2A7 CYP2A13 CYP2D7 CYP4B1 LIM2 SCN5A

7.34e-05881816CID000004060
Drug19-hydroxytestosterone

CYP2A7 CYP2A13 CYP2D7 CYP4B1

9.01e-05301814CID000150968
Drug11-H-14,15-EETA

CYP2A7 CYP2A13 CYP2D7 CYP4B1

9.01e-05301814CID011954058
Drug1,1-dichloroethylene

CYP2A7 CYP2A13 CYP2D7 CYP4B1 SLC16A7

1.15e-04601815CID000006366
DrugBP-7,8-oxide

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.17e-04321814CID000037455
Drug3-iodothyronamine

SLC9A8 SLC43A3 SLC7A2 SLC16A7

1.32e-04331814ctd:C487948
DrugAC1L1GOT

PTGER3 PTGER4 PTGFR

1.33e-04131813CID000003777
DrugN-0164

PTGER3 PTGER4 PTGFR

1.33e-04131813CID000173763
DrugNSC641089

PTGER3 PTGER4 PTGFR

1.33e-04131813CID003004260
DrugBW A868C

PTGDR PTGER3 PTGER4 PTGFR

1.49e-04341814CID000122021
Drug12(13)-EpOME

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.49e-04341814CID000001416
DrugTCEO

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.49e-04341814CID000028167
DrugAC1O5XSP

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.49e-04341814CID006442739
Drugisradipine

CYP2D7 CACNG3 CACNG2 TMEM37 SCN10A CACNG5

1.49e-041001816CID000003784
Drugisovalerate

GALNS CACNG3 CACNG2 SCN5A TMEM37 SLC13A5 CACNG5

1.51e-041431817CID000010430
Drugmibefradil

CACNG3 CACNG2 SCN5A TMEM37 CACNG5

1.57e-04641815CID000060662
Drugdihydropyridine

SLC22A7 SLC5A5 CACNG3 CACNG2 SSPN ATP2C2 TMEM37 CACNG5

1.62e-041931818CID000104822
DrugAH23848B

PTGDR PTGER3 PTGER4 PTGFR

1.67e-04351814CID005310999
Drugbimatoprost

PTGDR PTGER3 PTGER4 PTGFR

1.67e-04351814CID005311027
DrugAC1L1CJI

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.67e-04351814CID000001929
DrugCyclic AMP

NPPA HTR6 SLCO1B3 PTGER3 PTGER4 SLC4A2 KCND2 GLP1R CNR2

1.68e-042471819ctd:D000242
DrugAC1NSKAN

PTGDR PTGER3 PTGER4

1.69e-04141813CID005311244
Drugtetradotoxin

NPPA MRGPRD HTR6 PTGER3 KCND2 KCND3 SCN2A SCN5A SCN8A SCN10A HRH4 CNR2

1.71e-0442818112CID000020382
Drugmethanethiosulfonate

RHO SLC6A2 KCND1 KCND2 KCND3 SCN5A

1.75e-041031816CID004188587
DrugHydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A

PDE3B CYP4B1 PTGER3 ELMO1 KCND3 TMEM19 TM4SF20 MUSK

1.86e-0419718186011_UP
Drug15-H-11,12-EETA

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.87e-04361814CID011954042
DrugBAY u3405

PDE3B PTGDR PTGER3 PTGFR

1.87e-04361814CID000005036
DrugAC1L3NGJ

CYP2A7 CYP2A13 CYP2D7 CYP4B1

1.87e-04361814CID000092121
Drugiloperidone

HTR6 SLC6A2 TMEM37 HRH4

1.87e-04361814CID000071360
DrugDibucaine

SCN5A SCN10A

1.88e-0431812DB00527
Drug[18f]frb

SLC5A5 SLC6A2

1.88e-0431812CID009548004
Drug3-methylsulfonyl-4-piperidinobenzoyl guanidine

SLC9A8 SLC9A2

1.88e-0431812ctd:C074107
DrugAC1L1H0W

PTGER3 PTGER4

1.88e-0431812CID000003927
DrugMisoprostol

PTGER3 PTGER4

1.88e-0431812DB00929
Drug2'-methoxyacetophenone

CYP2A7 CYP2A13

1.88e-0431812CID000068481
DrugMS-245

HTR6 RHO

1.88e-0431812CID006918541
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A

NPPA SLC2A9 SLC22A7 KCND3 GLP1R GPR75 ACKR1 MUSK

1.99e-0419918186069_UP
Drugbutamben

KCND1 KCND2 KCND3

2.10e-04151813CID000002482
DrugONO-DI-004

PTGER3 PTGER4 MET

2.10e-04151813CID005311227
Drug5-iodonaphthyl-1-azide

RHO MS4A2 MS4A1

2.10e-04151813CID003035415
Drugtrichloroacetic acid

CYP2A7 CYP2A13 GALNS CYP2D7 CYP4B1 IGF2

2.16e-041071816CID000006421
Drugprocaine

MC1R CACNG3 CACNG2 TMEM37 SCN10A CACNG5 MUSK

2.28e-041531817CID000004914
Drug1h1q

CYP2A7 CYP2A13 CYP2D7 CYP4B1 UGT1A10

2.39e-04701815CID000001540
Drug4-bromophenol

CYP2A7 CYP2A13 CYP2D7 CYP4B1 CNR2

2.39e-04701815CID000007808
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

SLC26A9 TTYH3 SLC4A2 SLC5A5 SLC9A2 KCND3 SLC13A5 SLC16A7

2.52e-042061818CID000040600
Drug11,14,15-THET

CYP2A7 CYP2A13 CYP2D7 CYP4B1

2.56e-04391814CID006439531
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN5A SCN8A SCN10A

1.47e-09101705DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN5A SCN8A SCN10A

1.47e-09101705DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN5A SCN8A SCN10A

4.59e-09121705DOID:0060170 (implicated_via_orthology)
DiseaseParkinson disease, disease progression measurement

ANO2 AQP10 SLCO1B3 PI15 MCTP2

2.94e-06391705EFO_0008336, MONDO_0005180
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A ANO3

6.47e-0671703C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A ANO3

6.47e-0671703C0751057
DiseaseFebrile Convulsions

SCN1A SCN2A ANO3

1.54e-0591703C0009952
DiseaseAtrial standstill

NPPA SCN5A

3.30e-0521702C0541782
Diseaseretinitis pigmentosa 4 (implicated_via_orthology)

OPN4 RHO

3.30e-0521702DOID:0110372 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SV2A SCN1A SCN2A SCN5A SCN8A SCN10A SLC13A5

4.66e-051631707DOID:1826 (implicated_via_orthology)
DiseaseBrugada Syndrome 1

KCND3 SCN5A SCN10A

5.15e-05131703C4551804
DiseaseMMR-related febrile seizures

SCN1A SCN2A ANO3

8.12e-05151703EFO_0006519
DiseaseP wave duration

KCND3 SCN5A SCN10A

8.12e-05151703EFO_0005094
DiseaseCARDIOMYOPATHY, FAMILIAL, WITH CONDUCTION DISTURBANCE

NPPA SCN5A

9.86e-0531702C1838539
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

9.86e-0531702cv:C5575231
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A ANO3

1.44e-04181703HP_0002373
DiseaseBrugada ECG Pattern

SCN5A SCN10A

1.96e-0441702C1721096
DiseaseColorectal Neoplasms

ABCA3 ABCA4 SLCO1B3 ABCA10 ABCA8 ABCG1 IGF2 ABCB10

2.15e-042771708C0009404
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A CNR2

2.67e-04221703DOID:2030 (implicated_via_orthology)
Diseaseecosanoids measurement

CYP4B1 SLCO1B3 SLC22A10 MUSK

2.88e-04551704EFO_0020044
DiseaseBrugada Syndrome (disorder)

KCND3 SCN5A SCN10A

3.48e-04241703C1142166
DiseaseFEV change measurement, response to zileuton

SLC7A2 SLC16A7 LMBRD1

3.94e-04251703EFO_0005921, EFO_0007676
DiseaseEpilepsy

KCND2 ZDHHC9 SCN1A SCN2A SCN8A

4.31e-041091705C0014544
Disease1-stearoyl-GPC (18:0) measurement

MFSD2A MUSK

4.88e-0461702EFO_0800217
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

4.88e-0461702C0220669
Diseaseelectrocardiography, PR interval

SCN5A SCN10A

6.80e-0471702EFO_0004327, EFO_0004462
Diseasekallistatin measurement

SERPINA12 SERPINA1

9.03e-0481702EFO_0008196
DiseaseSudden Cardiac Arrest

KCND2 KCND3

9.03e-0481702C1720824
Disease1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) measurement

SIDT2 MUSK

1.16e-0391702EFO_0800409
Disease1-stearoyl-2-arachidonoyl-GPE (18:0/20:4) measurement

SIDT2 MUSK

1.16e-0391702EFO_0800403
Diseasesupraventricular ectopy

SCN5A SCN10A

1.16e-0391702EFO_0009277
Disease1-palmitoyl-2-linoleoyl-GPE (16:0/18:2) measurement

SIDT2 MUSK

1.16e-0391702EFO_0800272
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

1.16e-0391702C3502809
Diseaseserum metabolite measurement

ANGPT1 GPAA1 SLC2A9 CYP4B1 UGT1A10 HLA-DRB3 OR52L1 TAAR2 IGF2 PGAP2 HHAT CACNG5 PLTP MUSK

1.20e-0394517014EFO_0005653
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

PTGER3 SCN8A ANO3

1.26e-03371703EFO_0007645, EFO_0009458
Diseasesensory perception of sweet taste

SPAM1 TMEM14A PCDH10 ANO3

1.31e-03821704GO_0050916
Diseaseestrogen measurement

SLC22A9 SLC22A10

1.44e-03101702EFO_0011007
DiseaseReactive hypoglycemia

SERPINA1 IGF2

1.44e-03101702C0271710
DiseaseFasting Hypoglycemia

SERPINA1 IGF2

1.44e-03101702C0271708
Disease1-stearoyl-2-linoleoyl-GPE (18:0/18:2) measurement

SIDT2 MUSK

1.44e-03101702EFO_0800402
Diseasecholesteryl ester 22:5 measurement

SIDT2 MUSK

1.44e-03101702EFO_0021444
Diseasepancreatitis (biomarker_via_orthology)

MET SERPINA1 CNR2

1.47e-03391703DOID:4989 (biomarker_via_orthology)
Diseaseorofacial cleft, sex interaction measurement

PTGFR SLC7A2 SSPN SCN10A

1.56e-03861704EFO_0008343, MONDO_0000358
Diseasecholesteryl ester 18:3 measurement

ELMO1 SIDT2 MUSK

1.59e-03401703EFO_0010346
Diseasecholelithiasis

UGT1A10 ATP8B1 SERPINA1 MUSK

1.70e-03881704EFO_0004799
DiseaseOther specified cardiac arrhythmias

KCND3 SCN10A

1.75e-03111702C0348626
DiseaseNodal rhythm disorder

KCND3 SCN10A

1.75e-03111702C0264893
DiseaseEctopic rhythm

KCND3 SCN10A

1.75e-03111702C1399226
DiseaseHypoglycemia

SERPINA1 IGF2

1.75e-03111702C0020615
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

KCND3 SCN10A

1.75e-03111702C2748542
DiseaseSchizophrenia

ACSL6 HTR6 PTGER3 CACNG2 SLC6A2 MET IGF2 SV2A HHAT CACNG5 MCTP2 PLP1 CNR2

1.89e-0388317013C0036341
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 SLC6A2 MET SCN1A SCN2A

1.92e-031521705DOID:0060041 (implicated_via_orthology)
DiseasePathological accumulation of air in tissues

ABCA3 SERPINA1

2.10e-03121702C0013990
Diseasedodecanedioate measurement

UGT1A10 PGGT1B

2.10e-03121702EFO_0021054
Diseaseeconomic and social preference

SLC2A9 SLC22A9 SLC13A5 TMEM19

2.43e-03971704EFO_0004827
Diseaseinterleukin 6 receptor subunit alpha measurement

AQP10 NUP210L

2.47e-03131702EFO_0008187
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

2.47e-03131702C0751122
DiseaseX-24588 measurement

UGT1A10 SLCO1B3

2.47e-03131702EFO_0800898
DiseaseGranulomatosis with Polyangiitis

HLA-DRB3 MS4A10

2.47e-03131702EFO_0005297
DiseaseAlzheimer disease, APOE carrier status

ARSI SLC2A10 ANTXR1 MCTP2

2.52e-03981704EFO_0007659, MONDO_0004975
DiseaseColorectal Carcinoma

ABCA3 ABCA4 GALNS SLCO1B3 ABCA10 ABCA8 SLC22A9 ABCG1 IGF2 ABCB10 KCND3

2.61e-0370217011C0009402
Diseaseglycerophospholipid measurement

ANO2 SIDT2 MUSK

2.85e-03491703EFO_0007630
DiseaseT wave morphology measurement

SCN5A SCN10A

2.87e-03141702EFO_0008398
Diseasefamilial atrial fibrillation (is_implicated_in)

NPPA SCN5A

2.87e-03141702DOID:0050650 (is_implicated_in)
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

SLC43A3 LINGO1

2.87e-03141702EFO_0006830, EFO_0006896
Diseaseearly cardiac repolarization measurement

SLC9A8 KCND3

2.87e-03141702EFO_0004885
DiseaseLiver Cirrhosis

NPPA SERPINA1 LUM CNR2

3.02e-031031704C0023890
DiseaseFibrosis, Liver

NPPA SERPINA1 LUM CNR2

3.24e-031051704C0239946
DiseaseSinus Node Dysfunction (disorder)

KCND3 SCN10A

3.30e-03151702C0428908
Diseasegallstones

UGT1A10 ATP8B1 SERPINA1 MUSK

3.58e-031081704EFO_0004210
Disease5-oxoproline measurement

GPAA1 GLP1R

3.76e-03161702EFO_0010988
DiseaseRomano-Ward Syndrome

SCN5A SCN10A

3.76e-03161702C0035828
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

3.76e-03161702C0393706
DiseaseMalignant neoplasm of breast

ABCA3 ABCA4 ATP8B1 TTC3 SLC5A5 OR12D3 SLC2A10 SLC22A9 NLRP9 SLC9A2 ABCB10 EXOC3L1 PRRT1 CNR2

3.84e-03107417014C0006142
DiseaseX-21441 measurement

UGT1A10 SLCO1B3

4.24e-03171702EFO_0800814
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR7 TLR5

4.24e-03171702DOID:8677 (biomarker_via_orthology)
DiseaseLung Neoplasms

NPPA SLCO1B3 PGGT1B MET SERPINA1 SIDT2

4.47e-032651706C0024121
DiseaseMalignant neoplasm of lung

NPPA SLCO1B3 PGGT1B MET SERPINA1 SIDT2

4.55e-032661706C0242379
DiseaseCarcinoma, Granular Cell

NPPA MET SERPINA1 HRH4

4.62e-031161704C0205644
DiseaseAdenocarcinoma, Tubular

NPPA MET SERPINA1 HRH4

4.62e-031161704C0205645
DiseaseAdenocarcinoma, Oxyphilic

NPPA MET SERPINA1 HRH4

4.62e-031161704C0205642
DiseaseCarcinoma, Cribriform

NPPA MET SERPINA1 HRH4

4.62e-031161704C0205643
DiseaseAdenocarcinoma, Basal Cell

NPPA MET SERPINA1 HRH4

4.62e-031161704C0205641
DiseaseAdenocarcinoma

NPPA MET SERPINA1 HRH4

4.62e-031161704C0001418
DiseaseAlcoholic Intoxication, Chronic

CYP2A13 TAS2R38 SLC6A2 TAS2R16 PCDH10 CNR2

4.72e-032681706C0001973
Diseaseprotein Z-dependent protease inhibitor measurement

SERPINA12 SERPINA1

4.75e-03181702EFO_0021849
DiseaseBrugada syndrome

SCN5A SCN10A

5.29e-03191702MONDO_0015263
Diseaseosteoporosis (implicated_via_orthology)

PTGER4 IGF2

5.29e-03191702DOID:11476 (implicated_via_orthology)
Diseasemetabolite measurement

CYP2D7 GPAA1 SLC2A9 UGT1A10 SVOPL SLC22A9 SLC13A5 PLTP MUSK

5.35e-035601709EFO_0004725

Protein segments in the cluster

PeptideGeneStartEntry
MSSFSTTTVSFLLLL

NPPA

1

P01160
MALSELGTFLRSFSD

EXOC3L1

451

Q86VI1
IFFSISGMLSIISER

MS4A2

106

Q01362
ALLSLVLMAGTFFIA

SLC4A2

901

P04920
MSTAASLAFPFILIL

SLC4A2

1181

P04920
ASLTLGILLGMFFVT

HTR6

266

P50406
MEHSTFLSGLVLATL

CD3D

1

P04234
FGDMLSFTLTAFVEL

ELMO1

151

Q92556
SFIVFSTRGTTLMKL

ANTXR1

81

Q9H6X2
SSDFIRILVIFSGMF

CD27

186

P26842
VLSLLSPFAFTAGMA

ABCA10

271

Q8WWZ4
FLLAFSTATIMLCFL

ABCA4

736

P78363
AVRFVLFAALGTMTS

ABCG1

531

P45844
LFAALGTMTSLVAQS

ABCG1

536

P45844
SLSVLTFLFTVGLLM

ADAM21

691

Q9UKJ8
MHTLTGFSLVSLLSF

ARSI

1

Q5FYB1
FSPVSIATAFAMLSL

SERPINA1

76

P01009
LLSAILSMLSLSFST

GSG1

16

Q2KHT4
GTLSLGMFTSVFFLS

GPR33

106

Q49SQ1
FTMFLAGSLAVTIAI

AQP10

56

Q96PS8
LITTVGAFAAFSLMT

CACNG3

11

O60359
FAMAFLASTFSILAV

ABCA3

1106

Q99758
LAAAVGFLTMSSVIS

ABCB10

171

Q9NRK6
LGILASSTVLFMLFR

ACKR1

71

Q16570
MTVFLSFAFLAAILT

ANGPT1

1

Q15389
SILFMIALTFSIVFG

ANO2

541

Q9NQ90
SLSLFAAISGMILSI

MS4A1

121

P11836
TLSSGAVAALMAFLF

SLC7A2

391

P52569
MGSILLLVSFVLSSG

TMEM37

126

Q8WXS4
LSMFTIGVSLAVAAI

ATP2C2

321

O75185
SLLHGVLTSMILFFI

ATP8B1

1036

O43520
RLLVSVSGIFFMISL

ANO3

546

Q9BYT9
FLLKIGSVTMTFTAS

CNR2

106

P34972
FMSFFGLSSTLQLLA

PTGDR

111

Q13258
AAFTLMFTLALIFLS

OR6C1

201

Q96RD1
VADLFMVLGGFTSTL

RHO

81

P08100
SSMLSSLCFLGAIAV

MC1R

126

Q01726
FLMLFILSGSIQVFT

OR5H8

196

P0DN80
LLTTVGAFAAFSLMT

CACNG2

11

Q9Y698
LDIFTLLCSSFLTVM

OVOS1

271

Q6IE37
MVSFVLAGFTLLSSL

OR8I2

196

Q8N0Y5
LGCFLTFMVSESLLL

OR8U8

101

P0C7N1
MLVTLGLLTSFFSFL

RDH12

1

Q96NR8
FIVFIASSLGHMLLT

PGAP2

146

Q9UHJ9
SCASELGFLLFSLTM

KCND1

321

Q9NSA2
SCASELGFLLFSLTM

KCND3

316

Q9UK17
AGIMFFSSTLFVVLA

LIM2

101

P55344
MTLILTSLLFFGLSL

LILRA4

1

P59901
QRVITGTMALLFSFF

LRRTM2

421

O43300
LTTSDFMGSAFVILS

MCTP2

266

Q6DN12
ATGMAVALFSSVLAL

DOLK

116

Q9UPQ8
TNFSLGFLLATTMVP

GPAA1

516

O43292
TELSFTSFQGLMVAI

GLP1R

386

P43220
LMALSVSGIGLVSFA

SLC2A10

306

O95528
AALSFSISSLTLIGM

LMBRD1

191

Q9NUN5
FFSVIFMTVGILSNS

PTGFR

31

P43088
FAMIAFLSLDSSLQG

PCNX4

456

Q63HM2
DFLSTFITSGMRFLL

PLTP

166

P55058
ILSVMGVDSLFIGFS

OR51D1

216

Q8NGF3
IFLSMLASADVLLST

OR52B6

81

Q8NGF0
SGMISLASFFILIIS

OR4S1

201

Q8NGB4
SHLMVVTLLFGTALF

OR5A1

246

Q8NGJ0
FLMVFILSGSIQVFT

OR5H2

201

Q8NGV7
VISSLRSISSLMGAF

PDE3B

376

Q13370
TFFGLTMTVFGLSSL

PTGER3

131

P43115
TMTVFGLSSLFIASA

PTGER3

136

P43115
FFSLSGLSIICAMSV

PTGER4

101

P35408
MESSFSFGVILAVLA

GPR119

1

Q8TDV5
LSFCMLLAFSTLVST

INTS2

431

Q9H0H0
SFLISGILAITMKTF

MS4A10

101

Q96PG2
ADLLFLFSMASTLSL

MRGPRD

71

Q8TDS7
LAMSSSIFIGGSFIL

NIPA2

16

Q8N8Q9
ASELGFLLFSLTMAI

KCND2

321

Q9NZV8
FGSVSSVLFETLMDL

SLC16A7

351

O60669
SVFSLFMSRTSINGL

METTL9

106

Q9H1A3
GFGTMLSSVALLSIL

MPZL3

151

Q6UWV2
VFSSESAIFLLMLAT

LGR4

626

Q9BXB1
TLIIATTMGFISFLG

LINGO1

556

Q96FE5
LSTLLMSGSFNLSTL

MT-ND1

151

P03886
ALGSVSFIFLLAMIV

PCDH10

721

Q9P2E7
GTTEFLILTIMSFDR

OR6X1

106

Q8NH79
GFIALSQVLMFSISS

GPR151

286

Q8TDV0
FSISSANPLIFLVMS

GPR151

296

Q8TDV0
LAMAFTASIGSLLAI

GPR3

116

P46089
FHLTSSGFIIMSLKT

GPR75

121

O95800
LLSIVTGSISMGAFF

OR12D3

196

Q9UGF7
TGSISMGAFFLTLLS

OR12D3

201

Q9UGF7
SLTHLFLFSLTMVVF

OR2AE1

21

Q8NHA4
LLGTLFSTAMTFAFV

HHAT

361

Q5VTY9
ITGFLFTSLAFMLVE

MFSD2A

311

Q8NA29
ALFGISSMITLTAIA

OPN4

151

Q9UHM6
SIMDLFTTSLALAGL

GALNS

341

P34059
TVTLMVLSSRLAFAG

HLA-DRB3

16

P79483
FAAISFLLTESAGVM

CACNG5

181

Q9UF02
FISGILAALSAMISL

GPN3

151

Q9UHW5
LVMTTLNLFFAGTET

CYP2A13

291

Q16696
VSGMAISVLLLASDF

COLCA1

86

Q6ZS62
FLLSFLGMVGTLITT

CLDN14

11

O95500
DSSIMITSQILFFGF

GPR89A

6

B7ZAQ6
DSSIMITSQILFFGF

GPR89B

6

P0CG08
SFMALLTVGSERLFS

CALHM5

21

Q8N5C1
LLSMMLGIFQFTSTS

CYP2A7

201

P20853
GKSMLVLLTFLAFAS

IGF2

6

P01344
MSFETTAITFFIILL

C2orf74

1

A8MZ97
LLAVAMSFFGSALSI

ADA2

16

Q9NZK5
MSLSAFTLFLALIGG

LUM

1

P51884
MGLFFGTLTITLTLQ

SLC2A9

391

Q9NRM0
MVPSFLSLSFSSLGL

CYP4B1

1

P13584
PSTLSATMFIVSILF

SPAM1

486

P38567
ATMFIVSILFLIISS

SPAM1

491

P38567
FSFISLAVGIAAMVL

PRRT1

271

Q99946
VMFAITRTLTGSALA

SLC22A7

196

Q9Y694
VATTTLFLPIFASMS

SLC13A5

466

Q86YT5
LGIIFSSFMAASLLG

MFSD5

281

Q6N075
TLSAFPLGMSLTFTV

NUP210L

1396

Q5VU65
SMVTEFLLLGFSHLA

OR10C1

6

Q96KK4
MFRVGFLIISSSSSL

PCDH11Y

1

Q9BZA8
SFFMLISSLMFLSLS

REG1B

6

P48304
LTMVTEFLLLGFSSL

OR10R2

26

Q8NGX6
LMTSFSAGEIFILTA

OR14A2

101

Q96R54
FFFLTMACSEGLLLT

OR2L13

101

Q8N349
LATAVETGLLLTMAF

OR52I2

136

Q8NH67
MTLVSFFSFLSKPLI

OR52L1

1

Q8NGH7
LTFLSLLDVMFSSVV

OR4C6

61

Q8NH72
GISATLMIFSLLEFF

MS4A12

201

Q9NXJ0
SLSTRVTLAFFMSLV

HRH4

11

Q9H3N8
MGQFSEVLLTSISTF

MET

431

P08581
SRLTIAFFALSGLDM

PGGT1B

46

P53609
FIGLMILLTSAFSAG

PLAC1

6

Q9HBJ0
TGFVFGTTLIMLLSL

RTN3

856

O95197
GTTLIMLLSLAAFSV

RTN3

861

O95197
FLSEPMSTALFLLSL

RTTN

496

Q86VV8
MAALDSLSLFTSLGL

QARS1

1

P47897
LFLASTIFLMASLTK

TAS2R16

191

Q9NYV7
FLLFLVSSGMLTVSL

TAS2R38

206

P59533
VVFFVMLLALGLDSS

SLC6A2

406

P23975
FLSSIAMFGSFLVLL

SIDT2

801

Q8NBJ9
TFHTLILDMSGVSFV

SLC26A9

661

Q7LBE3
MATLSFVFLLLGAVS

POFUT2

1

Q9Y2G5
SLRFLSGIAAMSLIT

SLC22A9

201

Q8IVM8
VLRFLAGFSSMIIIS

SLC22A10

201

Q63ZE4
IIFMILLSSGALAFE

SCN5A

1211

Q14524
LFAFSLSVMAALTFG

SPCS3

11

P61009
QSSGMTIFFSLLVLA

SLC9A8

56

Q9Y2E8
IVLFFGSMLVTLGIS

SLC5A4

531

Q9NY91
SVATAFIASLVLGMI

SLC41A1

221

Q8IVJ1
AFTSAGSAVLLFLAM

SLC43A3

116

Q8NBI5
GFLMASISSSLLVRD

SSPN

71

Q14714
FLGTTDFFLLAVMSL

OR6T1

106

Q8NGN1
ILFTAGLCSFTAMLA

ST7

516

Q9NRC1
FLSFGNSESAMIALL

SV2A

641

Q7L0J3
RLSLSITMGCTALFF

SVOPL

371

Q8N434
ETFIVFMILLSSGAL

SCN1A

1221

P35498
NIFLSPLSISTAFSM

SERPINA12

71

Q8IW75
RTGMFLSSLFSVITV

TM4SF20

81

Q53R12
FSSLLTMDLGRVDTF

ABCA8

56

O94911
TQFIILSGFMVVFSL

ABCA8

291

O94911
FFRSLSATTLVSMGA

ACSL6

21

Q9UKU0
MGLTISSLFSRLFGK

ARF4

1

P18085
LMFFGILGATTLSVS

ATRAID

201

Q6UW56
NLFLAGMVTTSTTLA

CYP2D7

301

A0A087X1C5
TLLTQVGIFMFGIST

NLRP9

486

Q7RTR0
TVSLLLMAGLCTFFS

SLC49A3

421

Q6UXD7
ANMVLGLFSIIFSFS

TMEM269

41

A0A1B0GVZ9
SGMVILGVTSFSLLL

ZPLD1

376

Q8TCW7
FLFSMATLLRTSFSD

ZDHHC9

76

Q9Y397
FSLLMSSSSGFLDLF

UGT1A10

106

Q9HAW8
GSIIFSLSGVAFLLM

SPO16

46

Q5VVC0
LSSVSETLIFIFMGV

SLC9A2

366

Q9UBY0
LSLSASFMSAVQVLG

SLC5A5

61

Q92911
SFIIFMILLSSGSLA

SCN10A

1156

Q9Y5Y9
GIAKFSFLTSMISFL

SLCO1B3

406

Q9NPD5
ETFIVFMILLSSGAL

SCN2A

1211

Q99250
SLFTAFFLATIMGVR

TMEM14A

56

Q9Y6G1
GASLKLLDFSIMTFL

TTC3

926

P53804
ETFIIFMILLSSGAL

SCN8A

1201

Q9UQD0
LILSMAITDFLLGFT

TAAR2

81

Q9P1P5
ILFSLSISVSLFLMV

TLR7

841

Q9NYK1
FFTSLLMFFLSSSKL

TMEM19

96

Q96HH6
LTIFDLFSLMTCLIS

SLC30A6

66

Q6NXT4
SVFLGSGTQILIMTF

TM9SF2

366

Q99805
SGTQILIMTFVTLFF

TM9SF2

371

Q99805
DFLILILMFGGTSSN

TRAV40

6

A0A0B4J280
LSFLLMGTFLSVSQT

VPREB3

6

Q9UKI3
TLKTLLFFTALMITV

VMA21

26

Q3ZAQ7
LFGMVSVDSLLFVLS

TPTE2P1

71

Q5T6R2
MIAISAVSSALLFSL

PI15

1

O43692
TLFLMTILTVTKFRG

TLR5

651

O60602
LALFSFVTALMFSSI

TTYH3

391

Q9C0H2
FSTLLSLVGLLTSMT

TMEM239

171

Q8WW34
EFIFLIDRSSSMSGI

VWA5B1

361

Q5TIE3
SALALSFMLFGTLVA

XKR9

41

Q5GH70
GTFLRTLASSLMDFN

UNC79

2106

Q9P2D8
SILLLTLMLVFASFG

NALCN

1021

Q8IZF0
MSSFAIFVLLTITTL

MUSK

501

O15146
GAAATLVSLLTFMIA

PLP1

246

P60201