Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone phosphatase activity

EYA1 EYA2 EYA3

4.41e-0731533GO:0140789
GeneOntologyMolecularFunctionhistone H2AXY142 phosphatase activity

EYA1 EYA2 EYA3

4.41e-0731533GO:0140793
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

STAG1 PRICKLE1 TTLL5 CEP290 OBSL1 PEX14 EYA1 SIRT1 FSIP2 KIF3B RNF4 ALMS1 SENP6 CFAP206 CFAP74 KIF4B MAPRE2 TRIM37 STAG2

1.53e-0672015219GO:0000226
GeneOntologyBiologicalProcesschromosome segregation

STAG1 PRICKLE1 SRPK1 SMC5 SIRT1 NCAPG KIF3B RNF4 NUP37 CIAO1 TERB1 SENP6 KIF4B MAPRE2 STAG2

1.88e-0646515215GO:0007059
GeneOntologyBiologicalProcessmicrotubule-based process

STAG1 PRICKLE1 ADAM7 TTLL5 CEP290 OBSL1 PEX14 EYA1 SIRT1 FSIP2 KIF3B RNF4 ALMS1 FEZ1 SENP6 CFAP206 CFAP74 KIF4B CFAP61 BSN MAPRE2 TRIM37 STAG2

3.07e-06105815223GO:0007017
GeneOntologyBiologicalProcessorganelle assembly

RPGRIP1L NRAP STAG1 PRICKLE1 TTLL5 CEP290 OBSL1 SYT7 FSIP2 KIF3B RNF4 ALMS1 FEZ1 SENP6 CFAP206 CFAP74 KIF4B CFAP61 SEPTIN7 DNMBP MAPRE2 TRIM37 STAG2

1.01e-05113815223GO:0070925
GeneOntologyBiologicalProcessspindle assembly

STAG1 PRICKLE1 KIF3B RNF4 SENP6 KIF4B MAPRE2 STAG2

1.81e-051531528GO:0051225
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA4 EYA1 EYA2 EYA3 NF1

4.81e-05541525GO:2001239
GeneOntologyBiologicalProcessembryo development

TPO EYA4 RPGRIP1L PRICKLE1 CEP290 APBA2 ITGA8 PHF6 RICTOR TSC2 EYA1 EYA2 ITGA4 BMPR1A KMT2D FBN2 NF1 SALL1 TET1 LRP2 LRP4 AATF PLCD1 ALDH1A3 SEPTIN7

5.01e-05143715225GO:0009790
GeneOntologyBiologicalProcessmesodermal cell fate specification

EYA1 EYA2 BMPR1A

1.06e-04131523GO:0007501
GeneOntologyBiologicalProcesscilium assembly

RPGRIP1L PRICKLE1 TTLL5 CEP290 FSIP2 KIF3B ALMS1 CFAP206 CFAP74 CFAP61 SEPTIN7 DNMBP

1.15e-0444415212GO:0060271
GeneOntologyBiologicalProcessregulation of kinetochore assembly

RNF4 SENP6

1.61e-0431522GO:0090234
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

MAPKAP1 ARHGEF12 DGKZ TSC2 NF1 ARHGAP31 LRP4 FGD5 DNMBP MAPRE2

1.86e-0433315210GO:0051056
GeneOntologyBiologicalProcessnegative regulation of signal transduction in absence of ligand

EYA4 EYA1 EYA2 EYA3

2.11e-04401524GO:1901099
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA4 EYA1 EYA2 EYA3

2.11e-04401524GO:2001240
GeneOntologyBiologicalProcessmembraneless organelle assembly

NRAP STAG1 PRICKLE1 OBSL1 KIF3B RNF4 ALMS1 SENP6 KIF4B MAPRE2 TRIM37 STAG2

2.14e-0447515212GO:0140694
GeneOntologyBiologicalProcesscilium organization

RPGRIP1L PRICKLE1 TTLL5 CEP290 FSIP2 KIF3B ALMS1 CFAP206 CFAP74 CFAP61 SEPTIN7 DNMBP

2.19e-0447615212GO:0044782
GeneOntologyBiologicalProcessembryonic morphogenesis

EYA4 RPGRIP1L PRICKLE1 CEP290 ITGA8 TSC2 EYA1 EYA2 ITGA4 BMPR1A FBN2 SALL1 LRP2 LRP4 ALDH1A3

2.59e-0471315215GO:0048598
GeneOntologyBiologicalProcessspindle organization

STAG1 PRICKLE1 KIF3B RNF4 SENP6 KIF4B MAPRE2 STAG2

2.62e-042241528GO:0007051
DomainEYA_dom

EYA4 EYA1 EYA2 EYA3

3.89e-0941494IPR006545
DomainEYA_fam

EYA4 EYA1 EYA2 EYA3

3.89e-0941494IPR028472
DomaincEGF

FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.74e-06261495PF12662
DomaincEGF

FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.74e-06261495IPR026823
DomainEGF_CA

TPO COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

5.67e-06861497PF07645
DomainEGF_Ca-bd_CS

TPO COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.26e-05971497IPR018097
DomainEGF_CA

TPO COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.44e-05991497PS01187
Domain-

USP45 STUB1 RNF148 PHF6 KMT2C RNF113B KMT2D RNF4 SHPRH SCAF11 FGD5 BSN TRIM37 PDZRN4

1.49e-05449149143.30.40.10
DomainZnf_RING/FYVE/PHD

USP45 STUB1 RNF148 PHF6 KMT2C RNF113B KMT2D RNF4 SHPRH SCAF11 FGD5 BSN TRIM37 PDZRN4

1.90e-0545914914IPR013083
DomainEGF_CA

TPO COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

5.56e-051221497SM00179
DomainEGF-like_Ca-bd_dom

TPO COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

6.17e-051241497IPR001881
DomainARM-like

ZYG11A STAG1 RICTOR TSC2 HEATR1 HUWE1 NCAPG NF1 TERB1 STAG2

6.32e-0527014910IPR011989
DomainARM-type_fold

USP34 ZYG11A STAG1 RICTOR TSC2 HEATR1 HUWE1 NCAPG NF1 TERB1 STAG2

8.90e-0533914911IPR016024
DomainEGF

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.15e-042351499SM00181
DomainEGF_3

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.15e-042351499PS50026
DomainASX_HYDROXYL

TPO FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.50e-041001496PS00010
DomainEGF-like_dom

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.78e-042491499IPR000742
DomainEGF-type_Asp/Asn_hydroxyl_site

TPO FBN2 EFEMP1 HMCN1 LRP2 LRP4

2.06e-041061496IPR000152
DomainEGF_1

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

2.12e-042551499PS00022
DomainEGF-like_CS

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

2.52e-042611499IPR013032
DomainEGF_2

TPO COMP ADAM23 BCAN FBN2 EFEMP1 HMCN1 LRP2 LRP4

2.82e-042651499PS01186
DomainDISINTEGRIN_1

ADAM23 ADAM7 ADAMTS13 ADAMTS20

2.84e-04401494PS00427
DomainReprolysin

ADAM23 ADAM7 ADAMTS13 ADAMTS20

2.84e-04401494PF01421
DomainADAM_MEPRO

ADAM23 ADAM7 ADAMTS13 ADAMTS20

2.84e-04401494PS50215
DomainDISINTEGRIN_2

ADAM23 ADAM7 ADAMTS13 ADAMTS20

2.84e-04401494PS50214
DomainPeptidase_M12B

ADAM23 ADAM7 ADAMTS13 ADAMTS20

2.84e-04401494IPR001590
DomainDisintegrin_dom

ADAM23 ADAM7 ADAMTS13 ADAMTS20

3.13e-04411494IPR001762
DomainVDCC_L_bsu

CACNB1 CACNB4

3.75e-0441492IPR000584
DomainSCD

STAG1 STAG2

3.75e-0441492PS51425
DomainSCD

STAG1 STAG2

3.75e-0441492IPR020839
DomainSTAG

STAG1 STAG2

3.75e-0441492PF08514
DomainSTAG

STAG1 STAG2

3.75e-0441492IPR013721
DomainVGCC_beta4Aa_N

CACNB1 CACNB4

3.75e-0441492PF12052
DomainHAD-like_dom

EYA4 EYA2 NT5C2 PITPNM3 ATP2A1

4.24e-04791495IPR023214
DomainFYrich_C

KMT2C KMT2D

6.22e-0451492IPR003889
DomainFYrich_N

KMT2C KMT2D

6.22e-0451492IPR003888
DomainFYRC

KMT2C KMT2D

6.22e-0451492SM00542
DomainFYRN

KMT2C KMT2D

6.22e-0451492SM00541
DomainFYRN

KMT2C KMT2D

6.22e-0451492PF05964
DomainFYRC

KMT2C KMT2D

6.22e-0451492PF05965
DomainFYRC

KMT2C KMT2D

6.22e-0451492PS51543
DomainFYRN

KMT2C KMT2D

6.22e-0451492PS51542
DomainZF_RING_2

RNF148 KMT2C RNF113B KMT2D RNF4 SHPRH SCAF11 TRIM37 PDZRN4

6.60e-042981499PS50089
DomainFG_GAP

ITFG2 ITGA8 ITGA4

6.86e-04221493PS51470
DomainEPHD

PHF6 KMT2C KMT2D

6.86e-04221493PS51805
DomainRING

RNF148 KMT2C RNF113B KMT2D RNF4 SHPRH SCAF11 TRIM37 PDZRN4

7.78e-043051499SM00184
DomainPeptidase_M12B_ADAM-TS

PAPLN ADAMTS13 ADAMTS20

8.91e-04241493IPR013273
DomainFG-GAP

ITFG2 ITGA8 ITGA4

8.91e-04241493PF01839
DomainFG-GAP

ITFG2 ITGA8 ITGA4

8.91e-04241493IPR013517
DomainPET

TES PRICKLE1

9.29e-0461492PF06297
DomainPET_domain

TES PRICKLE1

9.29e-0461492IPR010442
DomainPET

TES PRICKLE1

9.29e-0461492PS51303
DomainZnf_RING

RNF148 KMT2C RNF113B KMT2D RNF4 SHPRH SCAF11 TRIM37 PDZRN4

1.24e-033261499IPR001841
DomainADAM_Cys-rich

ADAM23 ADAM7 ADAMTS13

1.26e-03271493IPR006586
DomainACR

ADAM23 ADAM7 ADAMTS13

1.26e-03271493SM00608
DomainGrowth_fac_rcpt_

COMP FBN2 EFEMP1 HMCN1 LRP2 LRP4

1.59e-031561496IPR009030
DomainTSP_1

PAPLN ADAMTS13 HMCN1 ADAMTS20

1.61e-03631494PF00090
Domain-

EYA4 EYA2 NT5C2 PITPNM3

1.71e-036414943.40.50.1000
DomainTSP1

PAPLN ADAMTS13 HMCN1 ADAMTS20

1.81e-03651494SM00209
DomainTSP1_rpt

PAPLN ADAMTS13 HMCN1 ADAMTS20

1.81e-03651494IPR000884
DomainTSP1

PAPLN ADAMTS13 HMCN1 ADAMTS20

1.81e-03651494PS50092
Domain-

ZYG11A RICTOR TSC2 HEATR1 NCAPG NF1 TERB1

2.06e-0322214971.25.10.10
DomainZF_RING_1

RNF148 RNF113B KMT2D RNF4 SHPRH SCAF11 TRIM37 PDZRN4

2.36e-032911498PS00518
DomainDAGK_acc

DGKB DGKZ

2.73e-03101492PF00609
DomainDiacylglycerol_kin_accessory

DGKB DGKZ

2.73e-03101492IPR000756
DomainDAGKa

DGKB DGKZ

2.73e-03101492SM00045
DomainIntegrin_alpha

ITGA8 ITGA4

3.32e-03111492PF00357
DomainPep_M12B_propep

ADAM23 ADAM7 ADAMTS20

3.69e-03391493PF01562
DomainPeptidase_M12B_N

ADAM23 ADAM7 ADAMTS20

3.69e-03391493IPR002870
Domain-

PON3 LRP2 LRP4

3.69e-033914932.120.10.30
Domain-

ADAM23 ADAM7 ADAMTS13 ADAMTS20

4.02e-038114943.40.390.10
DomainMetalloPept_cat_dom

ADAM23 ADAM7 ADAMTS13 ADAMTS20

4.02e-03811494IPR024079
DomainIg_I-set

IGFN1 CEACAM5 OBSL1 PAPLN HMCN1 IGLON5

4.23e-031901496IPR013098
DomainI-set

IGFN1 CEACAM5 OBSL1 PAPLN HMCN1 IGLON5

4.23e-031901496PF07679
DomainLdl_recept_b

LRP2 LRP4

5.40e-03141492PF00058
DomainLDLRB

LRP2 LRP4

5.40e-03141492PS51120
DomainDAGKc

DGKB DGKZ

5.40e-03141492SM00046
DomainPHD

PHF6 KMT2C KMT2D SHPRH

5.62e-03891494SM00249
Domain6-blade_b-propeller_TolB-like

PON3 LRP2 LRP4

5.88e-03461493IPR011042
DomainZnf_PHD

PHF6 KMT2C KMT2D SHPRH

6.08e-03911494IPR001965
DomainDiacylglycerol_kinase_cat_dom

DGKB DGKZ

6.20e-03151492IPR001206
DomainEF-hand_like

PLCD1 PLCL1

6.20e-03151492PF09279
DomainDAGK

DGKB DGKZ

6.20e-03151492PS50146
DomainPI-PLC-Y

PLCD1 PLCL1

6.20e-03151492PF00387
DomainPLCYc

PLCD1 PLCL1

6.20e-03151492SM00149
DomainLY

LRP2 LRP4

6.20e-03151492SM00135
DomainPLipase_C_Pinositol-sp_Y

PLCD1 PLCL1

6.20e-03151492IPR001711
DomainDAGK_cat

DGKB DGKZ

6.20e-03151492PF00781
DomainPIPLC_Y_DOMAIN

PLCD1 PLCL1

6.20e-03151492PS50008
DomainPI-PLC_fam

PLCD1 PLCL1

6.20e-03151492IPR001192
DomainPLC_EF-hand-like

PLCD1 PLCL1

6.20e-03151492IPR015359
DomainLDLR_classB_rpt

LRP2 LRP4

6.20e-03151492IPR000033
DomainZnf_FYVE_PHD

KMT2C KMT2D SHPRH FGD5 BSN

6.52e-031471495IPR011011
DomainPost-SET_dom

KMT2C KMT2D

7.05e-03161492IPR003616
DomainPostSET

KMT2C KMT2D

7.05e-03161492SM00508
DomainIntegrin_alpha_C_CS

ITGA8 ITGA4

7.05e-03161492IPR018184
DomainPOST_SET

KMT2C KMT2D

7.05e-03161492PS50868
DomainZF_PHD_2

PHF6 KMT2C KMT2D SHPRH

7.07e-03951494PS50016
DomainZF_PHD_1

PHF6 KMT2C KMT2D SHPRH

7.33e-03961494PS01359
DomainNAD/diacylglycerol_kinase

DGKB DGKZ

7.95e-03171492IPR016064
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 DCHS2 STUB1 STAG1 ADAM23 TTLL5 CEP290 APBA2 OBSL1 TSC2 HUWE1 EYA3 ANKRD6 CUEDC1 TARS3 EFEMP1 FEZ1 CLK1 NMT2 LRP2 SENP6 LRP4 SEPTIN7 TRIM37

4.46e-0912851582435914814
Pubmed

EYA4, a novel vertebrate gene related to Drosophila eyes absent.

EYA4 EYA1 EYA2 EYA3

6.11e-09615849887327
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 HIVEP1 RPGRIP1L STUB1 OBSL1 HUWE1 EYA3 SIRT1 SALL1 ALMS1 CIAO1 PRDX3 SENP6 BSN DNMBP TRIM37

1.31e-085881581638580884
Pubmed

A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

EYA1 EYA2 EYA3

9.20e-08315839020840
Pubmed

Eyes absent represents a class of protein tyrosine phosphatases.

EYA1 EYA2 EYA3

9.20e-083158314628052
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 EYA4 STUB1 BSPRY NUP88 OBSL1 SRPK1 DGKZ HEATR1 EYA1 HUWE1 EYA2 EYA3 DNAJC6 FAAP100 SIRT1 FBN2 CIAO1 ATP2A1

1.08e-079741581928675297
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

DMTF1 USP34 USP45 DGKZ RICTOR HEATR1 HUWE1 ANKRD6 KMT2C BMPR1A GLG1 KCNJ3 TET1 ZNF638 LRP2 OSBPL11 AATF TRIM37 STAG2 ATP6V0A2

1.19e-0710841582011544199
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RPGRIP1L CEP290 OBSL1 EYA1 HUWE1 GTF3C6 KMT2C KMT2D NCAPG ALMS1 ANGEL2 ZNF638 SCAF11

2.60e-074691581327634302
Pubmed

Misexpression of the eyes absent family triggers the apoptotic program.

EYA1 EYA2 EYA3

3.67e-074158311700312
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 HIVEP1 NUP88 HUWE1 GTF3C6 TXNIP KMT2D SALL1 ALMS1 ZFHX4 TET1 LRP2

5.28e-074181581234709266
Pubmed

Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya.

EYA1 EYA2 EYA3

9.14e-075158310490620
Pubmed

Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode.

EYA1 EYA2 EYA3

9.14e-07515839006082
Pubmed

Eyes absent: a gene family found in several metazoan phyla.

EYA1 EYA2 EYA3

9.14e-07515839195991
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MAPKAP1 CEACAM5 CLK4 ARHGEF12 PHF6 SRPK1 DGKZ RICTOR HEATR1 SYT7 CUEDC1 KMT2C NUP37 GLG1 NMT2 WDR89 INTS9 AATF SCAF11 DNMBP STAG2 ATP6V0A2

1.26e-0614971582231527615
Pubmed

Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.

MAPKAP1 RICTOR SIRT1

1.82e-066158322084251
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RPGRIP1L TTLL5 NUP88 KMT2D FBN2 ALMS1 ARHGAP31 TRIM37

2.16e-06184158832908313
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

HIVEP1 STUB1 RICTOR HUWE1 SIRT1 KMT2D SAFB NF1 ZNF638 OSBPL11 SENP6 ELF1 SCAF11 DNMBP STAG2

2.76e-067741581515302935
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

MAPKAP1 STUB1 NUP88 OBSL1 RICTOR TSC2 HEATR1 HUWE1 TAMM41 CIAO1 PRDX3 CDK5RAP1 INTS9

4.44e-066061581336538041
Pubmed

Interaction network of human early embryonic transcription factors.

EYA4 HIVEP1 NUP88 SIRT1 KMT2C KMT2D SALL1 ALMS1 ZFHX4 TET1

5.15e-063511581038297188
Pubmed

Dachshund homologues play a conserved role in islet cell development.

EYA4 EYA1 EYA2 EYA3

6.63e-0627158420869363
Pubmed

Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.

MAPKAP1 RICTOR NF1

7.57e-069158327340174
Pubmed

Global landscape of HIV-human protein complexes.

STUB1 ARHGEF12 HEATR1 HUWE1 ITGA4 SIRT1 FBN2 EFEMP1 ALMS1 GLG1 CIAO1

8.52e-064571581122190034
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

PHF6 SRPK1 TSC2 HUWE1 KMT2D NF1

9.37e-06106158631024071
Pubmed

STAG Mutations in Cancer.

STAG1 STAG2

2.05e-052158231421907
Pubmed

Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells.

STAG1 STAG2

2.05e-052158232778134
Pubmed

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.

MAPKAP1 RICTOR

2.05e-052158223030823
Pubmed

Nuclear import and export signals of human cohesins SA1/STAG1 and SA2/STAG2 expressed in Saccharomyces cerevisiae.

STAG1 STAG2

2.05e-052158222715410
Pubmed

Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1.

STAG1 STAG2

2.05e-052158228430577
Pubmed

The Integrator complex desensitizes cellular response to TGF-β/BMP signaling.

BMPR1A INTS9

2.05e-052158236641752
Pubmed

Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B.

SRPK1 SAFB

2.05e-052158211509566
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

2.05e-052158231924266
Pubmed

Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.

SRPK1 CLK1

2.05e-052158227397683
Pubmed

Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors.

CLK4 CLK1

2.05e-052158211461155
Pubmed

Molecular approach in the study of Alström syndrome: analysis of ten Spanish families.

RPGRIP1L ALMS1

2.05e-052158222876109
Pubmed

Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repair.

STAG1 STAG2

2.05e-052158224324008
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

2.05e-052158228967912
Pubmed

Familial transmission of oculoauriculovertebral spectrum (Goldenhar syndrome) is not due to mutations in either EYA1 or SALL1.

EYA1 SALL1

2.05e-052158219213029
Pubmed

Acquired Cystic Kidney Disease-associated Renal Cell Carcinoma (ACKD-RCC) Harbor Recurrent Mutations in KMT2C and TSC2 Genes.

TSC2 KMT2C

2.05e-052158232604168
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

2.05e-052158236601880
Pubmed

Critical roles for Rictor/Sin1 complexes in interferon-dependent gene transcription and generation of antiproliferative responses.

MAPKAP1 RICTOR

2.05e-052158224469448
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

2.05e-052158228483418
Pubmed

STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells.

STAG1 STAG2

2.05e-052158234648034
Pubmed

Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.

RPGRIP1L CEP290

2.05e-052158233625872
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

2.05e-052158234156443
Pubmed

Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer.

STAG1 STAG2

2.05e-052158229649003
Pubmed

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.

MAPKAP1 RICTOR

2.05e-052158235926713
Pubmed

Cohesin subunits, STAG1 and STAG2, and cohesin regulatory factor, PDS5b, in oral squamous cells carcinomas.

STAG1 STAG2

2.05e-052158227341316
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

2.05e-052158227280393
Pubmed

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.

STAG1 STAG2

2.05e-052158228691904
Pubmed

Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.

CACNB1 CACNB4

2.05e-052158214500989
Pubmed

Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.

STAG1 STAG2

2.05e-052158222415365
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

2.05e-052158236869380
Pubmed

Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells.

STAG1 STAG2

2.05e-052158219822671
Pubmed

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.

STAG1 STAG2

2.05e-052158232467316
Pubmed

Specialized functions of cohesins STAG1 and STAG2 in 3D genome architecture.

STAG1 STAG2

2.05e-052158232294612
Pubmed

Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.

STAG1 STAG2

2.05e-052158231495782
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

2.05e-052158225346535
Pubmed

A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor.

SRPK1 CLK1

2.05e-052158232359191
Pubmed

Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.

ITGA8 EYA1 SALL1 LRP2

2.41e-0537158416319116
Pubmed

Tagging genes with cassette-exchange sites.

ARHGEF12 PEX14 EYA3 SIRT1 KMT2C SAFB TET1 AATF SEPTIN7

2.45e-05335158915741177
Pubmed

BMP4 is essential for lens induction in the mouse embryo.

EYA1 EYA2 BMPR1A

2.54e-051315839851982
Pubmed

Human transcription factor protein interaction networks.

EYA4 HIVEP1 STUB1 NUP88 PHF6 EYA3 SIRT1 KMT2C KMT2D FBN2 SALL1 ALMS1 ZFHX4 PRDX3 NT5C2 ZNF638 LRP2 ELF1 SCAF11

2.84e-0514291581935140242
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNB1 CACNB4 ARHGEF12 DGKZ TSC2 HUWE1 DNAJC6 PPM1H KIF3B NF1 NT5C2 KIF4B PLCL1 SEPTIN7 BSN

3.60e-059631581528671696
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

HIVEP1 STUB1 PRICKLE1 PHF6 KMT2D NF1 SALL1 PITPNM3 AATF FGD5 BSN STAG2

3.79e-056381581231182584
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

HIVEP1 ARHGEF12 PHF6 SAFB NF1 ZFHX4 CLK1 DBR1 SLC17A6

4.37e-05361158926167880
Pubmed

Impact of WIN site inhibitor on the WDR5 interactome.

MAPKAP1 RICTOR KMT2C KMT2D

4.41e-0543158433472061
Pubmed

Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.

ITGA8 EYA1 SALL1

4.93e-0516158320439720
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IBA57 RPGRIP1L STUB1 TTLL5 OBSL1 PEX14 TSC2 HEATR1 HUWE1 LARS2 SIRT1 ALMS1 NUP37 PRDX3 ANGEL2 LRP2 OSBPL11 CDK5RAP1 AATF

5.26e-0514961581932877691
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

NUP88 HEATR1 NCAPG ZNF638 ELF1 AATF KIF4B SCAF11 MAPRE2

5.29e-05370158922922362
Pubmed

A comprehensive family-based replication study of schizophrenia genes.

FEZ1 ARHGAP31 NT5C2

5.97e-0517158323894747
Pubmed

Embryonic expression of three mouse genes with homology to the Drosophila melanogaster prickle gene.

TES PRICKLE1

6.13e-053158214516664
Pubmed

Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).

RICTOR PRDX3

6.13e-053158228986255
Pubmed

TRIM37 promotes the aggressiveness of ovarian cancer cells and increases c-Myc expression by binding to HUWE1.

HUWE1 TRIM37

6.13e-053158235921902
Pubmed

Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function.

EYA1 EYA2

6.13e-05315829342347
Pubmed

Characterization of the interaction between the cohesin subunits Rad21 and SA1/2.

STAG1 STAG2

6.13e-053158223874961
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

6.13e-053158223932714
Pubmed

Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue.

MAPKAP1 RICTOR

6.13e-053158227016480
Pubmed

Six and Eya expression during human somitogenesis and MyoD gene family activation.

EYA1 EYA2

6.13e-053158212500905
Pubmed

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.

EYA2 ALDH1A3

6.13e-053158214623956
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

6.13e-053158222183980
Pubmed

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.

RICTOR TSC2

6.13e-053158225893604
Pubmed

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

MAPKAP1 TSC2

6.13e-053158224161930
Pubmed

Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.

SRPK1 CLK1

6.13e-053158225529026
Pubmed

Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor.

CLK4 CLK1

6.13e-053158221949414
Pubmed

High glucose-induced PRDX3 acetylation contributes to glucotoxicity in pancreatic β-cells: Prevention by Teneligliptin.

SIRT1 PRDX3

6.13e-053158232763411
Pubmed

A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10.

EYA4 EYA1

6.13e-053158215492887
Pubmed

Morin Acts as a USP7 Inhibitor to Hold Back the Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes in a "Prickle1-mTORC2" Dependent Manner.

MAPKAP1 RICTOR

6.13e-053158234331380
Pubmed

Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.

CACNB1 CACNB4

6.13e-053158222737983
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

6.13e-053158221683083
Pubmed

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent.

EYA2 EYA3

6.13e-053158219351884
Pubmed

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.

SRPK1 SAFB

6.13e-053158219674106
Pubmed

Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction.

MAPKAP1 RICTOR

6.13e-053158221170086
Pubmed

Single-molecule imaging reveals a direct role of CTCF's zinc fingers in SA interaction and cluster-dependent RNA recruitment.

STAG1 STAG2

6.13e-053158238742641
Pubmed

Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications.

STAG1 STAG2

6.13e-053158224335498
Pubmed

Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty.

SRPK1 CLK1

6.13e-053158216223727
Pubmed

Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases.

SRPK1 CLK1

6.13e-053158223707382
Pubmed

Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation.

SRPK1 SAFB

6.13e-053158228627136
Pubmed

SIRT1 negatively regulates the mammalian target of rapamycin.

TSC2 SIRT1

6.13e-053158220169165
Pubmed

Detecting Low-Variant Allele Frequency Mosaic Pathogenic Variants of NF1, TSC2, and AKT3 Genes from Blood in Patients with Neurodevelopmental Disorders.

TSC2 NF1

6.13e-053158237088138
Pubmed

Mobilization of a splicing factor through a nuclear kinase-kinase complex.

SRPK1 CLK1

6.13e-053158229335301
InteractionDYRK1A interactions

USP34 DCHS2 TES ADAM23 NUP88 OBSL1 PHF6 SRPK1 TSC2 HUWE1 SIRT1 KMT2D EFEMP1 NF1 RNF4 FEZ1 LRP2 LRP4

2.39e-0755215418int:DYRK1A
InteractionKRT8 interactions

EYA4 TES RPGRIP1L TTLL5 NUP88 OBSL1 ARHGEF12 RICTOR ITGA4 ALMS1 CLK1 FGD5 DNMBP TRIM37

7.63e-0644115414int:KRT8
InteractionRBBP7 interactions

HIVEP1 STAG1 PHF6 RICTOR HUWE1 SMC5 SIRT1 TXNIP SAFB NCAPG SALL1 RNF4 TET1 SHPRH STAG2

8.29e-0650715415int:RBBP7
Cytoband12q12

PRICKLE1 ADAMTS20 SCAF11 PDZRN4

2.15e-0547158412q12
CytobandEnsembl 112 genes in cytogenetic band chr12q12

PRICKLE1 ADAMTS20 SCAF11 PDZRN4

6.87e-05631584chr12q12
Cytoband3q22.3

STAG1 NME9 DBR1

8.70e-052515833q22.3
Cytoband2q33

ADAM23 CLK1 PLCL1

1.37e-042915832q33
GeneFamilyEYA transcriptional coactivator and phosphatases

EYA4 EYA1 EYA2 EYA3

1.61e-09411641044
GeneFamilyCDC like kinases

CLK4 CLK1

2.43e-0441162480
GeneFamilyMTOR complex 1|MTOR complex 2

MAPKAP1 RICTOR

4.03e-04511621333
GeneFamilyCohesin complex

STAG1 STAG2

1.11e-03811621060
GeneFamilyFibulins

EFEMP1 HMCN1

1.11e-0381162556
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKB DGKZ

1.78e-031011621178
GeneFamilyRing finger proteins

RNF148 RNF113B RNF4 SHPRH SCAF11 TRIM37 PDZRN4

1.99e-03275116758
GeneFamilyPHD finger proteins

PHF6 KMT2C KMT2D SHPRH

2.69e-0390116488
GeneFamilyLow density lipoprotein receptors

LRP2 LRP4

3.04e-03131162634
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGFN1 CEACAM5 OBSL1 PAPLN HMCN1

3.82e-031611165593
GeneFamilyCD molecules|Integrin alpha subunits

ITGA8 ITGA4

5.84e-031811621160
GeneFamilyLIM domain containing

TES NRAP PRICKLE1

6.44e-035911631218
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS13 ADAMTS20

6.50e-0319116250
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCD1 PLCL1

6.50e-03191162832
CoexpressionGSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP

USP34 EYA4 CLK4 SRPK1 SMC5 SIRT1 GLG1 ZNF638 STAG2

3.69e-062001589M387
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_1_CELL

TES PAPLN BCAN EYA2 CUEDC1 FBN2 EFEMP1 ZFHX4 PLCL1 ALDH1A3

1.26e-0529415810M45674
CoexpressionGSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP

USP34 TES CLK4 ITGA4 ALMS1 CLK1 ELF1 IP6K2

2.92e-051991588M7596
CoexpressionGSE14308_TH1_VS_INDUCED_TREG_UP

CACNB4 STAG1 CLK4 PHF6 EYA2 PPM1H SENP6 FGD5

3.03e-052001588M3378
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN

USP45 EYA4 GLTP KIF3B ANGEL2 DBR1 STAG2 ATP6V0A2

3.03e-052001588M3963
CoexpressionGSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN

HUWE1 EYA2 ITGA4 NDRG3 RTP4 TXNIP RNASEL ELF1

3.03e-052001588M6563
CoexpressionGSE7852_LN_VS_THYMUS_TCONV_DN

DMTF1 ITFG2 PRICKLE1 CEP290 SMC5 STRIP2 SAFB TRIM37

3.03e-052001588M5746
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000

EYA4 ADAM23 EYA1 HUWE1 ITGA4 SALL1 HMCN1 ZFHX4 FEZ1 ADAMTS20

1.23e-0524315510gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3
CoexpressionAtlasDevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_100

EYA4 EYA1 ANKRD6 SALL1

2.59e-05241554gudmap_developingKidney_e11.5_metaneph mesench_100_k4
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

EYA4 ADAM23 ITGA8 EYA1 FBN2 SALL1 HMCN1 LRP4

3.06e-051661558gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ZYG11A HORMAD2 ADAM23 TTLL5 NUP88 HEATR1 HUWE1 SIRT1 KMT2C TARS3 NCAPG ALMS1 NMT2 TET1 CDK5RAP1 AATF CFAP61 TRIM37

3.16e-0582015518gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

DMTF1 FAM13C CLK4 ARHGEF12 LARS2 LYSMD3 GTF3C6 SIRT1 KIF3B CLK1 ATAD2B SENP6 CFAP74 TRIM37 STAG2

3.17e-0559515515Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

CACNB4 EYA4 ADAM23 EYA1 TARS3 SALL1 HMCN1

3.37e-051231557gudmap_kidney_P3_CapMes_Crym_k3_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

EYA4 FAM13C ADAM23 ITGA8 DGKB EYA1 HUWE1 ANKRD6 DNAJC6 ZFHX4 SHPRH ALDH1A3

7.30e-0542715512DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

USP45 EYA4 FAM13C ADAM23 PHF6 EYA1 HUWE1 ANKRD6 FBN2 SALL1 ZFHX4 MAPRE2

7.63e-0542915512gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlaskidney_P1_CapMes_Crym_top-relative-expression-ranked_100

EYA4 ITGA8 EYA1 SALL1 HMCN1

8.99e-05621555gudmap_kidney_P1_CapMes_Crym_100
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_100

EYA4 ITGA8 EYA1 SALL1 HMCN1

9.71e-05631555gudmap_kidney_P0_CapMes_Crym_100
CoexpressionAtlasDevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_200

EYA4 EYA1 ANKRD6 SALL1

1.07e-04341554gudmap_developingKidney_e11.5_metaneph mesench_200_k2
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

ZYG11A NUP88 RICTOR HEATR1 SIRT1 NCAPG NMT2 CDK5RAP1 AATF TRIM37

1.73e-0433315510gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4

HTR1B FAM13C ITGA8 DGKB ITGA4 RTP4 TXNIP PLCL1

1.87e-042151558facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4
CoexpressionAtlaskidney_P1_CapMes_Crym_top-relative-expression-ranked_200

CACNB4 EYA4 ITGA8 EYA1 SALL1 HMCN1

2.53e-041201556gudmap_kidney_P1_CapMes_Crym_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000

EYA4 EYA1 HUWE1 ANKRD6 ZFHX4 ADAMTS20

2.53e-041201556gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_100

CACNB4 EYA4 EYA1 ANKRD6 SALL1

2.67e-04781555gudmap_developingKidney_e15.5_Cap mesenchyme_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000

EYA4 PRICKLE1 EYA1 HUWE1 ANKRD6 SALL1 ZFHX4 ADAMTS20

2.86e-042291558gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_500

EYA4 FAM13C ADAM23 EYA1 ITGA4 ANKRD6 DNAJC6 EFEMP1 SALL1 ZFHX4 FEZ1

2.92e-0442415511gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000

EYA4 ARHGEF12 PHF6 EYA1 ANKRD6 PPM1H TARS3 NCAPG SALL1

3.11e-042931559gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_100

ITGA8 DGKB ITGA4 RTP4 PLCL1

3.18e-04811555gudmap_kidney_adult_Mesangium_Meis_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

EYA4 FAM13C ADAM23 ITGA8 DGKB EYA1 HUWE1 ITGA4 ANKRD6 DNAJC6 EFEMP1 SALL1 ZFHX4 SHPRH ADAMTS20 ALDH1A3

3.29e-0481815516DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

ZYG11A ADAM23 TTLL5 NUP88 HEATR1 SIRT1 NCAPG NMT2 AATF TRIM37

3.30e-0436115510gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlaskidney_P2_CapMes_Crym_top-relative-expression-ranked_100

EYA4 ITGA8 EYA1 SALL1 HMCN1

3.77e-04841555gudmap_kidney_P2_CapMes_Crym_100
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#1_top-relative-expression-ranked_200

EYA4 EYA1 FBN2 SALL1

3.82e-04471554gudmap_kidney_P4_CapMesRenVes_Crym_k1_200
CoexpressionAtlasDevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_100

EYA4 EYA1 ANKRD6 SYT7 SALL1

3.98e-04851555gudmap_developingKidney_e11.5_metaneph mesench_100
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

CACNB4 EYA4 ADAM23 ITGA8 EYA1 TARS3 FBN2 SALL1 HMCN1 LRP4

4.01e-0437015510gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

USP45 EYA4 FAM13C ADAM23 PHF6 EYA1 HUWE1 ITGA4 ANKRD6 DNAJC6 FBN2 SALL1 HMCN1 ZFHX4 MAPRE2 TRIM37

4.17e-0483615516gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_500

EYA4 EYA1 HUWE1 ANKRD6 ZFHX4

4.20e-04861555DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000

USP34 EYA4 FAM13C PHF6 FBN2 TET1 ADAMTS20 SCAF11 MAPRE2

4.37e-043071559gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3
CoexpressionAtlasDevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_1000

EYA4 EYA1 ANKRD6 SYT7 SALL1

4.92e-04891555gudmap_developingKidney_e11.5_metaneph mesench_1000_k2
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_100

EYA4 ITGA8 EYA1 SALL1 LRP4

4.92e-04891555gudmap_kidney_P3_CapMes_Crym_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

USP45 EYA4 ITFG2 FAM13C PRICKLE1 ADAM23 PHF6 EYA1 HUWE1 ANKRD6 FBN2 SALL1 HMCN1 ZFHX4 MAPRE2 TRIM37

5.00e-0485015516gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500

ADAM23 EYA1 HUWE1 ITGA4 SALL1 ZFHX4

5.14e-041371556gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500

EYA2 ITGA4 SYT7 FBN2 RNASEL EFEMP1 HMCN1 ZFHX4 ADAMTS20 MAPRE2

5.80e-0438815510gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000

EYA4 EYA1 HUWE1 ANKRD6 SALL1 ZFHX4 ADAMTS20

6.04e-041961557DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

USP45 RPGRIP1L TTLL5 CEP290 NUP88 ARHGEF12 HUWE1 ANKRD6 SMC5 NDRG3 ATAD2B TET1 ADAMTS20 SCAF11 DBR1

6.04e-0478015515Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

TES ADAM23 CEP290 SMC5 ALMS1 TET1 ZNF638 OSBPL11 INTS9 CFAP74 SCAF11

6.78e-0446915511Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#3_top-relative-expression-ranked_100

EYA4 ANKRD6 SALL1

6.90e-04241553gudmap_developingKidney_e15.5_Cap mesenchyme_100_k3
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

HIVEP1 FAM13C PRICKLE1 EYA2 ITGA4 SYT7 FBN2 RNASEL EFEMP1 HMCN1 ZFHX4 CLK1 ADAMTS20 ALDH1A3 MAPRE2

6.97e-0479115515gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 DGKB ITGA4 ANKRD6 STRIP2 ZFHX4 ALDH1A3 SLC17A6

1.15e-071611588e3327c296d48e821004e61a573abb75624a6f040
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TES PRICKLE1 ITGA8 EYA2 ITGA4 FBN2 ZFHX4 SEPTIN7

2.83e-0718115889b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

USP34 STAG1 ARHGEF12 PHF6 ALMS1 HMCN1 OSBPL11 SCAF11

3.48e-07186158803db813598b67b1e08f759758a1c2023396921fa
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

EYA4 NRAP ARHGEF12 EYA1 FBN2 PLCL1 CFAP61 MAPRE2

3.93e-0718915880a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPKAP1 USP34 SMC5 RNASEL SENP6 SCAF11 SEPTIN7 STAG2

4.26e-07191158860c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPKAP1 USP34 SMC5 RNASEL SENP6 SCAF11 SEPTIN7 STAG2

4.26e-071911588973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 PAPLN ADAMTS13 ITGA4 FBN2 EFEMP1 SALL1 LRP4

5.38e-0719715882e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 DGKB ITGA4 ANKRD6 STRIP2 ZFHX4 SLC17A6

1.45e-06156158709e0702400570089d9012dcf94dfb4827c97e49d
ToppCellwk_08-11-Epithelial-PNS-Late_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAM23 DGKB BCAN ITGA4 RTP4 ALDH1A3 MAPRE2

3.48e-061781587a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TES PAPLN BCAN EYA2 FBN2 ZFHX4 ALDH1A3

3.88e-0618115877e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellRV|World / Chamber and Cluster_Paper

NRAP ADAM23 EYA1 TXNIP FBN2 PLCL1 CFAP61

3.88e-061811587bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM23 DGKB ITGA4 RTP4 ZFHX4 ALDH1A3 PDZRN4

4.02e-061821587bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 DGKB FBN2 HMCN1 ZFHX4 LRP2 ADAMTS20

4.32e-0618415872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 DGKB FBN2 HMCN1 ZFHX4 LRP2 ADAMTS20

4.32e-061841587ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 DGKB FBN2 HMCN1 ZFHX4 LRP2 ADAMTS20

4.32e-0618415872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IGFN1 PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

4.81e-0618715874d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

ADAM23 EYA1 NDRG3 PEBP4 FBN2 PLCL1 CFAP61

4.81e-06187158778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 CUEDC1 TXNIP ZFHX4 ARHGAP31 LRP4

5.16e-06189158737ecbd73408d462b47d7e5611f203143e08a2689
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPKAP1 USP34 RNASEL SENP6 SCAF11 SEPTIN7 STAG2

5.53e-06191158709db184cb90fe282a14474d7217068c58092c6f8
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 PAPLN ADAMTS13 FBN2 EFEMP1 SALL1 LRP4

6.77e-0619715871da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DCHS2 EYA4 COMP ECM2 ITGA8 BCAN HMCN1

6.77e-06197158744673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 ITGA8 ANKRD6 STRIP2 ZFHX4 ALDH1A3

7.75e-061321586ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKB FBN2 HMCN1 ZFHX4 LRP2 PDZRN4

2.31e-051601586c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKB FBN2 HMCN1 ZFHX4 LRP2 PDZRN4

2.31e-05160158625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO1H PTCHD1 TARS3 NT5C2 CDK5RAP1 PLCL1

2.85e-051661586de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BCAN EYA1 ITGA4 PPM1H NMT2 ATP6V0A2

3.47e-0517215867fb43b3938b9a3b6935ec22d9d853e7d47b82b3c
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAG1 ECM2 HMCN1 KCNJ3 ZNF638 SCAF11

3.95e-051761586749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCTD7 RPGRIP1L ECM2 ITGA8 ALMS1 TAMM41

4.48e-051801586d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

EYA1 CFAP206 CFAP74 CFAP61 KIAA2012 MAP3K19

4.76e-051821586fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ECM2 ITGA4 ANKRD6 HMCN1 ZFHX4 ARHGAP31

5.06e-05184158667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP SALL1 HMCN1 ARHGAP31 WDR89 TRIM37

5.06e-051841586f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

CACNB1 PRICKLE1 HEATR1 NCAPG CFAP74 PNMA3

5.06e-0518415862e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 PAPLN ADAMTS13 EFEMP1 ALDH1A3 IGLON5

5.21e-051851586f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 PAPLN ADAMTS13 EFEMP1 ALDH1A3 IGLON5

5.21e-05185158640e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 PAPLN ADAMTS13 EFEMP1 ALDH1A3 IGLON5

5.21e-0518515865f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

EYA1 NME9 CFAP74 CFAP61 KIAA2012 MAP3K19

5.21e-05185158630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES ADAM23 TTLL5 ITGA4 STRIP2 PTCHD1

5.21e-05185158619fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

EYA1 CFAP206 CFAP74 CFAP61 KIAA2012 MAP3K19

5.21e-05185158618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PON3 PAPLN EYA1 EYA2 EFEMP1 LRP4

5.37e-05186158673cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA1 SALL1 HMCN1 ARHGAP31 FGD5 TRIM37

5.37e-0518615860ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A PAPLN EYA2 STRIP2 GLG1 LRP2

5.37e-0518615865784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

5.53e-0518715865d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

5.53e-0518715865c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

5.53e-05187158693c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 RICTOR HUWE1 KMT2C NF1 MAPRE2

5.70e-051881586ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL5 HMCN1 ARHGAP31 ATAD2B SHPRH INTS9

5.70e-0518815866468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL5 HMCN1 ARHGAP31 ATAD2B SHPRH INTS9

5.70e-0518815867a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL5 HMCN1 ARHGAP31 ATAD2B SHPRH INTS9

5.70e-0518815869cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUEDC1 TXNIP ZFHX4 ARHGAP31 LRP2 LRP4

5.87e-05189158642ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAM23 ECM2 TTLL5 ITGA8 EYA2 FBN2

6.04e-0519015863aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

EYA4 NRAP ARHGEF12 EYA1 PLCL1 MAPRE2

6.04e-05190158693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COMP ECM2 ITGA8 HMCN1 ZFHX4 FEZ1

6.22e-051911586f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellfacs-Heart-RV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP EYA1 SALL1 HMCN1 ARHGAP31 TRIM37

6.22e-051911586f0c649bb32732c9dd38a0af8ce94d2a4d16de39a
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COMP ECM2 ITGA8 HMCN1 ZFHX4 FEZ1

6.22e-051911586387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP EYA1 SALL1 HMCN1 ARHGAP31 TRIM37

6.22e-051911586e518c598719119e60c76016c586b1520c258bbcb
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

6.40e-05192158643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

6.59e-051931586b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN EYA2 EFEMP1 ZFHX4 ARHGAP31 LRP4

6.59e-05193158640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PRICKLE1 ADAM23 HMCN1 FGD5 ALDH1A3 IGLON5

6.59e-051931586194e7fa00a50cc4e026987b715323d125d79594e
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPO IGFN1 BSPRY LARS2 SALL1 LRP2

6.78e-0519415863701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPO IGFN1 BSPRY LARS2 SALL1 LRP2

6.78e-05194158665f9bf126be26114c2c3f4c46d48318986212a92
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

EYA4 NRAP PRICKLE1 KCNJ3 PLCL1 MAPRE2

6.78e-051941586c3535f7cc0076653c72db582047cff053c322397
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM13C PRICKLE1 ADAM23 ARHGEF12 HMCN1 FGD5

6.78e-0519415867f24023df47935286f185dd428d48797daf26f49
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCAN RTP4 FBN2 ZFHX4 ALDH1A3 SEPTIN7

6.98e-05195158619347b7e8d3ea67e0fddd948078abcab9d364a2d
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCAN RTP4 FBN2 ZFHX4 ALDH1A3 SEPTIN7

6.98e-05195158655b4030f078173b0136990fae87b6eaf44c58f33
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA8 EYA1 EFEMP1 ZFHX4 LRP4 ALDH1A3

7.18e-05196158657df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

CACNB4 EYA2 EFEMP1 ELF1 FGD5 PDZRN4

7.18e-0519615864930eeb303d174c28fd91021723e26fdf1af9170
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 PAPLN ADAMTS13 EFEMP1 SALL1 LRP4

7.38e-051971586ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NRAP MYO1H PAPLN CFAP206 CFAP74 MAP3K19

7.38e-0519715866e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 ADAMTS13 FBN2 EFEMP1 SALL1 LRP4

7.59e-0519815864a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ECM2 ITGA8 BMPR1A EFEMP1 ZFHX4 LRP4

7.59e-051981586bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCellstromal_cell|World / Lineage and Cell class

FAM13C ECM2 EYA1 EFEMP1 ZFHX4 ALDH1A3

7.80e-051991586507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

FAM13C ECM2 EYA1 EFEMP1 ZFHX4 ALDH1A3

7.80e-05199158674262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 TXNIP FBN2 EFEMP1 ALDH1A3 SEPTIN7

7.80e-05199158634199597371a20d9f1dea9ad59edfb615b14c4f6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 ADAMTS13 ITGA4 TXNIP EFEMP1 SALL1

7.80e-05199158605777e92344aedabfb5a72207c6632dc64205534
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 ITGA4 KMT2C CLK1 ATAD2B SCAF11

8.02e-05200158612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Ptrf|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 ADAMTS13 STRIP2 ZFHX4 ALDH1A3

1.12e-041331585a1bc34e5dda4ff4716b857931cc196f6770f58f4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 ANKRD6 STRIP2 ZFHX4 ALDH1A3

1.85e-041481585d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PAPLN ANKRD6 PPM1H PTCHD1 HMCN1

2.03e-0415115854533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PAPLN ANKRD6 PPM1H PTCHD1 HMCN1

2.03e-041511585edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DCHS2 ADAMTS13 EYA1 IGLV9-49 CFAP61

2.16e-041531585a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EYA4 NME9 CFAP61 KIAA2012 MAP3K19

2.22e-0415415854e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EYA4 NME9 CFAP61 KIAA2012 MAP3K19

2.22e-0415415857556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE1 DNAJC6 MGAT3 TET1 FGD5

2.29e-041551585e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ECM2 ITGA8 PTCHD1 CFAP206 PDZRN4

2.36e-041561585d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ECM2 ITGA8 PTCHD1 CFAP206 PDZRN4

2.36e-041561585363f1b661048d25895e2b8681c82894c957b29c0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA4 ANKRD6 ZFHX4 ALDH1A3 PDZRN4

2.36e-0415615852cd007b423c2395c5ce331902e7f27c805755eb3
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 FEZ1 KCNJ3 LRP4 ALDH1A3

2.73e-041611585da9eecf919866a9c579d7a707a996cf335213134
ToppCelldroplet-Heart-nan-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP PPM1H TXNIP SALL1 WDR89

2.73e-041611585eb546d5065ac506405d240f9a1f55f2122d0c368
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 FEZ1 KCNJ3 LRP4 ALDH1A3

2.73e-041611585d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 ITGA8 DGKB ADAMTS13 STRIP2

2.81e-0416215852d28306c6125b31f11ea6d911a167b93a74907c5
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7|TCGA-Stomach / Sample_Type by Project: Shred V9

DGKB PEBP4 PTCHD1 PLCL1 PDZRN4

2.81e-041621585b115b5799137122bd60696f8ae2aebadad6cd044
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

EYA4 EYA1 CFAP206 CFAP74 MAP3K19

2.97e-0416415850e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB1 ITFG2 ECM2 STRIP2 NCAPG

3.06e-0416515850edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-1|TCGA-Ovary / Sample_Type by Project: Shred V9

FBN2 SALL1 TET1 LRP4 IGLON5

3.06e-0416515852ca1154a8692af311d99a4d3aa2f2ac3d23a4310
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB1 ITFG2 ECM2 STRIP2 NCAPG

3.06e-041651585fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE1 ADAM23 ITGA8 CCDC168 ZFHX4

3.14e-0416615857286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE1 ADAM23 ITGA8 CCDC168 ZFHX4

3.14e-0416615857c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

RPGRIP1L PCNX4 CFAP206 KIAA2012 MAP3K19

3.23e-04167158526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DGKB EYA1 ITGA4 ALDH1A3 PDZRN4

3.23e-04167158549b19159c62d33d65ed1e59a148c11ae902fd41c
Diseaseeye disease (implicated_via_orthology)

EYA4 EYA1 EYA2 EYA3

1.01e-0861524DOID:5614 (implicated_via_orthology)
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA4 EYA1 EYA2 EYA3

2.34e-0871524DOID:14702 (implicated_via_orthology)
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

2.64e-0521522DOID:0080598 (implicated_via_orthology)
Diseasecup-to-disc ratio measurement

HORMAD2 MYO1H DGKB EYA1 EYA2 EFEMP1 SALL1 GLG1 TET1 IP6K2

8.30e-0543015210EFO_0006939
Diseasecognitive function measurement, self reported educational attainment

SYT7 MGAT3 ALMS1 KCNJ3 ZNF638 PLCL1 BSN TRIM37 IP6K2

9.90e-053551529EFO_0004784, EFO_0008354
Diseasefacial morphology

HTR1B ITGA8 DNAJC6 MAPRE2

1.88e-04551524EFO_0004743
DiseasePolydactyly

RPGRIP1L CEP290 SALL1 ALMS1 LRP4

3.58e-041171525C0152427
Diseaserenal cell carcinoma (implicated_via_orthology)

TSC2 TXNIP

3.90e-0461522DOID:4450 (implicated_via_orthology)
Diseasevenous thromboembolism, fibrinogen measurement

DCHS2 DGKZ LRP4 PMFBP1

4.03e-04671524EFO_0004286, EFO_0004623
Diseasereaction time measurement

FAM13C ITGA8 DGKZ KMT2D KCNJ3 ATAD2B TET1 PITPNM3 ZNF638 LRP4 PDZRN4

6.34e-0465815211EFO_0008393
Diseasechronotype measurement

USP34 HIVEP1 KMT2D RNASEL ATAD2B TET1 NT5C2 PLCL1 CFAP61 BSN TRIM37 IP6K2 PMFBP1

6.71e-0488215213EFO_0008328
Diseaseposterior thigh muscle fat infiltration measurement

EYA4 EYA1 EYA2

7.77e-04351523EFO_0020934
DiseaseDisorder of eye

KCTD7 RPGRIP1L CEP290 EFEMP1 ALMS1 PITPNM3

8.32e-042121526C0015397
Diseaseobesity (implicated_via_orthology)

DCHS2 SIRT1 ALMS1 ZFHX4 NT5C2 ADAMTS20

8.95e-042151526DOID:9970 (implicated_via_orthology)
Diseaseage at menarche

USP34 HTR1B MYO1H DNAJC6 ALMS1 ZFHX4 SENP6 PLCL1 CFAP61 BSN

1.06e-0359415210EFO_0004703
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

RPGRIP1L STAG1 KMT2D MGAT3 KCNJ3 ZNF638 PLCL1 BSN

1.11e-033981528EFO_0003756, EFO_0003888, EFO_0004337
Diseasecentral corneal thickness

STAG1 SMC5 RTP4 FBN2 EFEMP1 NUP37 ADAMTS20

1.15e-033091527EFO_0005213
DiseaseMeckel-Gruber syndrome

RPGRIP1L CEP290

1.15e-03101522cv:C0265215
Disease2-ketocaprylate measurement

ALMS1 PCNX4

1.15e-03101522EFO_0800110
DiseaseCongenital small ears

EYA1 KMT2D SALL1

1.24e-03411523C0152423
Diseaseworry measurement

HIVEP1 STAG1 MYO1H NT5C2 PLCL1

1.24e-031541525EFO_0009589
DiseaseCongenital Abnormality

EYA1 SALL1

1.41e-03111522C0000768
Diseasesmoking cessation

MAPKAP1 RPGRIP1L STAG1 DGKZ ALMS1 ATAD2B BSN

1.53e-033251527EFO_0004319
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

RICTOR KMT2C KMT2D

1.62e-03451523DOID:3748 (is_implicated_in)
Diseaseanthropometric measurement

DMTF1 MYO1H EYA1 EFEMP1 BSN

1.82e-031681525EFO_0004302
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP1 BMPR1A

1.98e-03131522DOID:0050787 (implicated_via_orthology)
DiseaseMental Retardation, X-Linked Nonsyndromic

HUWE1 PTCHD1

1.98e-03131522C3501611
DiseaseBardet-Biedl Syndrome

CEP290 ALMS1

1.98e-03131522C0752166
Diseaserisk-taking behaviour

HIVEP1 STAG1 NF1 NUP37 GLG1 KCNJ3 ATAD2B LRP4 ATP2A1 KIAA2012 PMFBP1

2.09e-0376415211EFO_0008579
Diseasecorneal resistance factor

STAG1 BSPRY ARHGEF12 SMC5 FBN2 EFEMP1 TET1 ADAMTS20

2.42e-034511528EFO_0010067
Diseasenon-alcoholic fatty liver disease

STAG1 ITGA8 EYA1 EYA2 DNMBP

2.58e-031821525EFO_0003095
DiseaseMeckel-Gruber syndrome

RPGRIP1L CEP290

2.65e-03151522C0265215
Diseaseneutrophil-to-lymphocyte ratio

HORMAD2 HIVEP1 ITGA4 ATAD2B ELF1

2.76e-031851525EFO_0008447
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

HIVEP1 STAG1 NUP88 TET1 KIAA2012 PMFBP1 PDZRN4

2.89e-033641527EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseDiffuse Large B-Cell Lymphoma

TXNIP KMT2D PRDX3

2.89e-03551523C0079744
Diseasemean reticulocyte volume

ZYG11A SRPK1 ITGA4 SAFB ATAD2B ZNF638 ELF1 DBR1 TRIM37 STAG2 PMFBP1

2.94e-0379915211EFO_0010701
Diseaseuterine prolapse

FBN2 EFEMP1

3.02e-03161522EFO_1001864
Diseasebody composition measurement

EYA4 EYA1 EYA2 EFEMP1 AATF

3.31e-031931525EFO_0005106
Diseaselevel of Sphingomyelin (d32:1) in blood serum

NUP88 WDR89

3.41e-03171522OBA_2045173
Diseasehealth study participation

DGKB NCAPG RNF4 PLCL1 IP6K2

3.46e-031951525EFO_0010130
DiseaseColorectal Carcinoma

CACNB1 EYA4 KMT2C BMPR1A NCAPG FBN2 EFEMP1 NF1 LRP2 PDZRN4

3.56e-0370215210C0009402
Diseasemigraine disorder, type 2 diabetes mellitus

EYA1 SENP6 KIAA2012

3.70e-03601523MONDO_0005148, MONDO_0005277
DiseaseMeckel syndrome type 1

RPGRIP1L CEP290

3.82e-03181522C3714506
Diseasecortical surface area measurement

USP34 DCHS2 TES STAG1 ARHGEF12 EYA1 FBN2 ARHGAP31 ATAD2B NT5C2 ADAMTS20 PLCL1 MAPRE2 IP6K2 PDZRN4

4.11e-03134515215EFO_0010736
DiseaseFamilial aplasia of the vermis

RPGRIP1L CEP290

4.71e-03201522cv:C0431399

Protein segments in the cluster

PeptideGeneStartEntry
KAEEEVSECVVNTDH

HTR1B

191

P28222
EAQDEENHAVVCEVE

CFAP61

221

Q8NHU2
DDDDDITLTVEASCH

ELF1

76

P32519
EASCHDGDETIETIE

ELF1

86

P32519
DCSGAHVVLDDDTDV

ADAM23

691

O75077
DIILDENQLEDACEH

CACNB1

386

Q02641
PQEITHCHDEDDDEE

NT5C2

541

P49902
CSELFDDEAIESHDI

ADAM7

511

Q9H2U9
YECGIQNELSVDHSD

CEACAM5

391

P06731
VDHDFVGDACDSDQD

COMP

421

P49747
LQINIEESECHSEFE

ALMS1

3456

Q8TCU4
ADADLDLAVECAHQG

ALDH1A3

291

P47895
QEHSEVSGFLLECDS

IBA57

116

Q5T440
DCLENTLGVEEQRHE

DNMBP

326

Q6XZF7
AHPVDTDECQEAVEE

APBA2

126

Q99767
FDADVLCLQEVQEDH

ANGEL2

211

Q5VTE6
DVILDENQLEDACEH

CACNB4

376

O00305
LHCPQNEADEIDSED

DMTF1

31

Q9Y222
CTEDNTHFEGIDCEV

ATP2A1

876

O14983
HGEDDGEEILLDTQC

ADAMTS13

981

Q76LX8
ELASAVLEDTECHEA

ADAMTS20

1106

P59510
CDLDVQDDGDQTALH

ANKRD6

66

Q9Y2G4
VQEEECEVERVTEHG

ARHGEF12

721

Q9NZN5
EIGQECAAHGEIVSE

CFAP206

16

Q8IYR0
VEDDEEGHLICQSGD

CLK1

141

P49759
TIECNQGEQEGVEHE

PDZRN4

651

Q6ZMN7
EECDQVHVEDVASDD

EYA3

361

Q99504
IQIEEDSTHIICDND

INTS9

626

Q9NV88
HDLEVTEGDTATFEC

OBSL1

1636

O75147
RCEVQHGIDDSSDAV

BCAN

136

Q96GW7
QDFDCQEHDIETTHG

NDRG3

26

Q9UGV2
ESDGQLFEHHCEVDV

KCTD7

216

Q96MP8
SSEVKHICGEDQIED

KMT2C

631

Q8NEZ4
VHAFGNCSDSDILEE

LYSMD3

21

Q7Z3D4
TCGIDGDNEEETEHA

NMT2

21

O60551
DEQDLECEDIGVAHV

RPGRIP1L

1246

Q68CZ1
HELGDVVDAFVVCES

MGAT3

226

Q09327
GDHGIVDIVDNSDCE

IP6K2

91

Q9UHH9
EAISGIHDQEDGEQC

NRAP

81

Q86VF7
ENSTTEIAHQGLDCD

HORMAD2

251

Q8N7B1
NGEFEVSTDCHEENG

ATAD2B

1181

Q9ULI0
VSTDCHEENGEETGD

ATAD2B

1186

Q9ULI0
CVVSDSEAYHLGQEE

BSN

3566

Q9UPA5
QEDLISSTGEAEDCH

FSIP2

6801

Q5CZC0
AEEDEHEFTSCTGAE

PCNX4

111

Q63HM2
DIPDDCEEHEFQEAV

PNMA6F

21

A0A0J9YX94
NIQEEDESDYHCGAD

IGLV9-49

101

A0A0B4J1Y8
ESVENGDFVHCEESG

TPO

746

P07202
ENSPCAHEALLDEDT

PEBP4

26

Q96S96
STANLLDDVEGHACD

CUEDC1

351

Q9NWM3
TLEDHAQDESAEESC

FGD5

311

Q6ZNL6
FNDLEECDQVHIDDV

EYA1

376

Q99502
ECDQVHIDDVSSDDN

EYA1

381

Q99502
DETQAEDTSIENHLC

KIAA2012

271

Q0VF49
IEALNGNCSDTEIHE

FEZ1

126

Q99689
GNCSDTEIHEKEEEE

FEZ1

131

Q99689
VDNDCGDHSDEPIEE

LRP2

3656

P98164
EGQEIASVSDDHTCR

NUP37

136

Q8NFH4
EAAENFLPDEDVHCD

FAAP100

296

Q0VG06
HSCSEEGLEDAANVL

HUWE1

3591

Q7Z6Z7
STEDTGLQEHTDDNC

RICTOR

1506

Q6R327
VSEQAHILVDCGEDN

ITGA8

631

P53708
HAICLGDVDNDTLNE

ITFG2

21

Q969R8
EGSEASHDTCVDIDE

HMCN1

5421

Q96RW7
VDIDECENTDACQHE

HMCN1

5431

Q96RW7
HIIDGNTDECFTINE

DCHS2

1866

Q6V1P9
RECDHSQTDSLEDEE

PLCD1

186

P51178
EIIFADECTEAEGRH

PRICKLE1

196

Q96MT3
TETGQELECLQDHLD

GLG1

651

Q92896
LEECDQVHIDDVSSD

EYA4

426

O95677
EGDNATLSCFIDEHV

IGLON5

46

A6NGN9
CESEEQRLLEQVHGE

BSPRY

121

Q5W0U4
ISGIESDDHCQREQE

CEP290

2046

O15078
ELEECQRNHEGDEDD

STUB1

176

Q9UNE7
GDEDDSHVRAQQACI

STUB1

186

Q9UNE7
CEEDHAALVNQESEQ

DNAJC6

441

O75061
HCFAIIEEDDQGETT

BMPR1A

81

P36894
LHESVEIECDGVQID

DGKB

636

Q9Y6T7
ICNAEEDDDSNLEHL

ECM2

651

O94769
VFLQSICDGERDENH

GLTP

106

Q9NZD2
ELLCQEHGQENDDLV

MAPRE2

276

Q15555
DLSITVHATCENEEE

ITGA4

741

P13612
SLSEVHGQVLESEDC

KIF4B

801

Q2VIQ3
HVCGEYEEQDDVESN

DBR1

391

Q9UK59
AETHCEEQGDAVFEC

IGFN1

316

Q86VF2
HSENDLEEVGKTENC

HEATR1

1881

Q9H583
CQENHGHITEEEEEV

CCDC168

2336

Q8NDH2
SRSIEDDEEGHLICQ

CLK4

136

Q9HAZ1
DDEEGHLICQSGDVL

CLK4

141

Q9HAZ1
LDAVEENGETCLHQA

DGKZ

851

Q13574
HDTREDVNECLESPG

FBN2

2166

P35556
GHVETEDVEIIATCD

SCAF11

636

Q99590
DQVDCSDLSEHNGLD

SALL1

106

Q9NSC2
CLLQEAEDDVDPGHS

CFAP74

36

Q9C0B2
EEFDQDGDCSHSTLV

MAP3K19

46

Q56UN5
DGDCSHSTLVNEEED

MAP3K19

51

Q56UN5
EEINADDEIEDTCDH

OSBPL11

341

Q9BXB4
CVVLEGEEEDDHTSE

NUP88

336

Q99567
EDCDQIHVDDVSSDD

EYA2

326

O00167
EEAALAGCHLEDTQR

PMFBP1

491

Q8TBY8
SEHNVCQDIDECTAG

EFEMP1

166

Q12805
LEVSLEGSHDTANCE

RTP4

141

Q96DX8
GSEEDEAHEGCSREN

SYT7

121

O43581
DAHIFCTVEQIEEEI

TARS3

541

A2RTX5
IECDTENEEQEEHTS

TRIM37

906

O94972
CGQEEHDVLLSNEED

TES

46

Q9UGI8
GTCVIFEENVEHADT

GTF3C6

71

Q969F1
CNFLHENEDEEVVAS

GTF3C6

141

Q969F1
QGTFGECDSEVDVLH

STRIP2

136

Q9ULQ0
DQTVLANEQVDEHGC

LARS2

211

Q15031
VVDRESSHDGCQDAL

NBPF8

206

Q3BBV2
VVDRESSHDGCQDAL

NBPF11

241

Q86T75
CICEDENHEVGSEEE

RNF113B

236

Q8IZP6
EGEEANTYESHLLVC

PTCHD1

471

Q96NR3
GEDEFEETLQEACRH

PNMA3

31

Q9UL41
LEACLDVHRGEDVEN

RNASEL

441

Q05823
CLHIAEDDGEVDTDF

MAPKAP1

231

Q9BPZ7
SEFNQEHETEDCAES

SHPRH

621

Q149N8
EHETEDCAESLNHAD

SHPRH

626

Q149N8
EIITNGFHSCESDEE

SIRT1

151

Q96EB6
EFHDVNCEVVAVSVD

PRDX3

121

P30048
AEIPCEDEQEQEHNG

SRPK1

451

Q96SB4
ECDEDPVSLHEDQTD

FAM13C

21

Q8NE31
DDDVSHVDEEDCLGV

PEX14

331

O75381
EAEIDNGSVADCVED

SAFB

136

Q15424
DDLSCQDATHTQIEE

TET1

1061

Q8NFU7
DLGAAEEQECGDHRE

AATF

121

Q9NY61
NQDDFECVTTLEGHE

CIAO1

91

O76071
HCEGTEINSDDEQES

NCAPG

666

Q9BPX3
FCGETEEDHVQTVSL

CDK5RAP1

446

Q96SZ6
TSEEKCGFIHEDELD

SLC17A6

511

Q9P2U8
CGFIHEDELDEETGD

SLC17A6

516

Q9P2U8
AEQGVTHITEDICLD

PLCL1

341

Q15111
CKNHSGNDERDEEDE

PHF6

326

Q8IWS0
TCDDDLTEQHEEAEG

ZFHX4

1091

Q86UP3
REGVENACFSSEEHE

TMEM74B

56

Q9NUR3
EDSSDDIAVGLTCQH

USP45

26

Q70EL2
SVEEGLECNEHEKTF

ZNF177

251

Q13360
VVGCDHELDSSKQED

PAPLN

156

O95428
FLGLSQDEVECSADH

PPM1H

46

Q9ULR3
EGDEELDLNEDNCVV

RNF148

246

Q8N7C7
SEEVLTAEDCENVYH

STAG2

401

Q8N3U4
ITIECSEVGLDGENH

KIF3B

221

O15066
VAEVENGEHCDFTIL

SEPTIN7

271

Q16181
DHADSCVVSSDDEEL

RNF4

86

P78317
VCSEDNVDVHDIELL

NF1

166

P21359
EADIRCGVDEVSVHN

NF1

716

P21359
ISVTNEDLHCLNEGE

SENP6

666

Q9GZR1
EDLHCLNEGEFLNDV

SENP6

671

Q9GZR1
LHGSEEALSNEDCEN

STAG1

401

Q8WVM7
NCHLIEELESGSEDI

PON3

41

Q15166
SDCDEDDTVTDIAQH

ARHGAP31

886

Q2M1Z3
DEDECVSHGKNNGED

NME9

136

Q86XW9
DVEETLFQVAHDPDC

TAMM41

271

Q96BW9
AQGSIEIHEDSEEGC

PITPNM3

106

Q9BZ71
LLGERVDENTEENHC

ZNF844

66

Q08AG5
ESGCEEELVQINSHA

USP34

796

Q70CQ2
NDHIICAGTEKVDDD

WDR89

126

Q96FK6
EGDEISIHADFENTC

TXNIP

191

Q9H3M7
QCAGEVDLHTENEED

SMC5

951

Q8IY18
EEEGLQLLCDIQEHS

ZYG11A

711

Q6WRX3
LGHCTEDCEENQYDL

TERB1

321

Q8NA31
EEPDRDLEAQCHDQE

HIVEP1

1241

P15822
DELIDQDDCISHSEP

ZNF638

1646

Q14966
SEDEEVISQEDHPCI

TTLL5

16

Q6EMB2
VEELCDQNEFHGSQE

TSC2

391

P49815
DIEEGNHQVEDGCRE

ATP6V0A2

706

Q9Y487
DAVDICNEAAVHDIS

nan

171

Q8N402
HAGCESLFTEDDVEQ

KMT2D

1531

O14686
ERHNSVECLDGLDDI

KCNJ3

381

P48549
LTEDGHTCQDVNECA

LRP4

386

O75096
EDDQGCATIPDTHEI

MYO1H

286

Q8N1T3