Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	TGFb_propeptide	GDF6 MSTN GDF11	8.81e-05	28	58	3	PF00688
Domain	TGF-b_N	GDF6 MSTN GDF11	8.81e-05	28	58	3	IPR001111
Domain	TGF-beta-rel	GDF6 MSTN GDF11	1.32e-04	32	58	3	IPR015615
Domain	TGFb_CS	GDF6 MSTN GDF11	1.32e-04	32	58	3	IPR017948
Domain	TGFB	GDF6 MSTN GDF11	2.05e-04	37	58	3	SM00204
Domain	Cadherin_tail	PCDHA11 PCDHA10 PCDHA3	2.05e-04	37	58	3	PF15974
Domain	TGF-b_C	GDF6 MSTN GDF11	2.05e-04	37	58	3	IPR001839
Domain	TGF_BETA_2	GDF6 MSTN GDF11	2.05e-04	37	58	3	PS51362
Domain	TGF_beta	GDF6 MSTN GDF11	2.05e-04	37	58	3	PF00019
Domain	TGF_BETA_1	GDF6 MSTN GDF11	2.05e-04	37	58	3	PS00250
Domain	Cadherin_CBD	PCDHA11 PCDHA10 PCDHA3	2.05e-04	37	58	3	IPR031904
Domain	Quinoprot_gluc/sorb_DH	TRIM56 LRP1	6.13e-04	12	58	2	IPR011041
Domain	Cadherin_2	PCDHA11 PCDHA10 PCDHA3	1.08e-03	65	58	3	PF08266
Domain	Cadherin_N	PCDHA11 PCDHA10 PCDHA3	1.08e-03	65	58	3	IPR013164
Domain	-	GDF6 MSTN GDF11	1.18e-03	67	58	3	2.10.90.10
Domain	Cystine-knot_cytokine	GDF6 MSTN GDF11	1.18e-03	67	58	3	IPR029034
Domain	CTCK_1	SLIT3 MUC5AC	1.40e-03	18	58	2	PS01185
Domain	CT	SLIT3 MUC5AC	2.10e-03	22	58	2	SM00041
Domain	Cys_knot_C	SLIT3 MUC5AC	2.72e-03	25	58	2	IPR006207
Domain	CTCK_2	SLIT3 MUC5AC	2.72e-03	25	58	2	PS01225
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	RELN PCDHA11 PCDHA10 PCDHA3	2.24e-08	18	59	4	15570159
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA11 PCDHA10 PCDHA3	2.08e-06	15	59	3	15640798
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	RELN PCDHA11 PCDHA10 PCDHA3	2.76e-06	57	59	4	32633719
Pubmed	GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone.	MSTN GDF11	2.83e-06	2	59	2	32071240
Pubmed	The Growth Differentiation Factor 11 (GDF11) and Myostatin (MSTN) in tissue specific aging.	MSTN GDF11	2.83e-06	2	59	2	28472635
Pubmed	Relationship between serum level of growth differentiation factors 8, 11 and bone mineral density in girls with anorexia nervosa.	MSTN GDF11	2.83e-06	2	59	2	30281844
Pubmed	Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.	MSTN GDF11	2.83e-06	2	59	2	26489925
Pubmed	Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.	MSTN GDF11	2.83e-06	2	59	2	36631218
Pubmed	Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.	MSTN GDF11	2.83e-06	2	59	2	27304512
Pubmed	Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain.	MSTN GDF11	2.83e-06	2	59	2	26372181
Pubmed	Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor.	TPP2 RYR3	2.83e-06	2	59	2	23818952
Pubmed	Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.	MSTN GDF11	2.83e-06	2	59	2	27034275
Pubmed	Supraphysiological levels of GDF11 induce striated muscle atrophy.	MSTN GDF11	2.83e-06	2	59	2	28270449
Pubmed	Redundancy of myostatin and growth/differentiation factor 11 function.	MSTN GDF11	2.83e-06	2	59	2	19298661
Pubmed	Myostatin and the control of skeletal muscle mass.	MSTN GDF11	2.83e-06	2	59	2	10508689
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	RELN PCDHA11 PCDHA10 PCDHA3	2.96e-06	58	59	4	30377227
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA11 PCDHA10 PCDHA3	3.10e-06	17	59	3	29911975
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA11 PCDHA10 PCDHA3	3.72e-06	18	59	3	10662547
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	PCDHA11 PCDHA10 PCDHA3 NR3C1	8.30e-06	75	59	4	15372022
Pubmed	Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11.	MSTN GDF11	8.48e-06	3	59	2	30814254
Pubmed	The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men.	MSTN GDF11	8.48e-06	3	59	2	32035222
Pubmed	Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction.	NR3C1 MSTN	8.48e-06	3	59	2	23516508
Pubmed	Structural basis for potency differences between GDF8 and GDF11.	MSTN GDF11	8.48e-06	3	59	2	28257634
Pubmed	Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression.	NR3C1 MUC5AC	8.48e-06	3	59	2	22798432
Pubmed	Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men.	MSTN GDF11	8.48e-06	3	59	2	30165829
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHA11 PCDHA10 PCDHA3	9.15e-06	24	59	3	24698270
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHA11 PCDHA10 PCDHA3	1.47e-05	28	59	3	15347688
Pubmed	Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development.	MSTN GDF11	1.69e-05	4	59	2	17878677
Pubmed	The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis.	FNDC3B SQSTM1	1.69e-05	4	59	2	32966780
Pubmed	Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.	MSTN GDF11	1.69e-05	4	59	2	18596030
Pubmed	Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin.	MSTN GDF11	1.69e-05	4	59	2	18535106
Pubmed	Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ.	MSTN GDF11	2.82e-05	5	59	2	27148972
Pubmed	BMP-11 and myostatin support undifferentiated growth of human embryonic stem cells in feeder-free cultures.	MSTN GDF11	4.23e-05	6	59	2	19751112
Pubmed	Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?	SCN11A CACNA1H	4.23e-05	6	59	2	17513486
Pubmed	The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone.	RELN MAP1A	4.23e-05	6	59	2	20667915
Pubmed	Autoregulation of neurogenesis by GDF11.	MSTN GDF11	7.87e-05	8	59	2	12546816
Pubmed	Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.	RELN LRP1	7.87e-05	8	59	2	10380922
Pubmed	A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.	MSTN GDF11	7.87e-05	8	59	2	31187730
Pubmed	Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.	MAP1A SQSTM1	1.01e-04	9	59	2	18083104
Pubmed	TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.	GDF6 MSTN GDF11	1.14e-04	55	59	3	15342483
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	ELAPOR2 SQSTM1 KRT85 HCFC1 RYR3	1.22e-04	284	59	5	29459677
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA11 PCDHA10	1.54e-04	11	59	2	9655502
Pubmed	Proteins of the CNR family are multiple receptors for Reelin.	RELN PCDHA11	1.85e-04	12	59	2	10612399
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHA11 PCDHA10 PCDHA3	2.15e-04	68	59	3	11230163
Pubmed	Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain.	RELN SEMA6A	2.54e-04	14	59	2	22821687
Pubmed	NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1.	SQSTM1 NEK9	2.54e-04	14	59	2	31857374
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	ADAMTS16 MUC5AC	2.54e-04	14	59	2	31242448
Pubmed	A Method to Identify p62's UBA Domain Interacting Proteins.	RELN SQSTM1	2.54e-04	14	59	2	14702098
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHA11 PCDHA10 PCDHA3	2.54e-04	72	59	3	10380929
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	IRF2BP1 MAP1A SQSTM1 LRP1	2.75e-04	184	59	4	32908313
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHA11 PCDHA10 PCDHA3	2.76e-04	74	59	3	10817752
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	ADAMTS16 MUC5AC	2.93e-04	15	59	2	7543410
Pubmed	Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.	MSTN GDF11	2.93e-04	15	59	2	24019467
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHA11 PCDHA10 PCDHA3	3.10e-04	77	59	3	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHA11 PCDHA10 PCDHA3	3.47e-04	80	59	3	10716726
Pubmed	Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2.	RELN SEMA6A	4.75e-04	19	59	2	17493606
Pubmed	FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.	RELN SLIT3	5.27e-04	20	59	2	30392794
Pubmed	Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development.	SLIT3 SEMA6A	5.27e-04	20	59	2	30819894
Pubmed	Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.	RELN SLIT3	5.27e-04	20	59	2	29961574
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	IL16 MAP1A SQSTM1 TRIM56 LRP1 PEX6 KAT6B ZNF687	5.70e-04	1116	59	8	31753913
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	TPP2 COL6A2 CRYBG1 NR3C1	5.97e-04	226	59	4	37839992
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	COL6A2 MAP1A	6.39e-04	22	59	2	12812986
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	SLIT3 LRP1 SEMA6A	6.67e-04	100	59	3	25807483
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FNDC3B COL6A2 CASKIN2 PEX6 NR3C1 HCFC1	8.10e-04	650	59	6	38777146
Pubmed	Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.	SQSTM1 NEK9	8.96e-04	26	59	2	24067654
Pubmed	Gamma protocadherins are required for survival of spinal interneurons.	RELN PCDHA11	8.96e-04	26	59	2	12467588
Pubmed	The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways.	RELN SEMA6A	8.96e-04	26	59	2	23988635
Pubmed	Conditionals by inversion provide a universal method for the generation of conditional alleles.	MSTN GDF11	9.66e-04	27	59	2	23918385
Pubmed	Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.	NR3C1 HCFC1	9.66e-04	27	59	2	21233130
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	SLIT3 SEMA6A	1.04e-03	28	59	2	18617019
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	PCDHA11 PCDHA10 PCDHA3	1.10e-03	119	59	3	28625976
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	TPP2 SQSTM1 NEK9 HCFC1	1.11e-03	267	59	4	33417871
Pubmed	SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets.	SQSTM1 TRIM56	1.19e-03	30	59	2	34780058
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	RELN PCDHA3	1.19e-03	30	59	2	19054571
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	GDF6 NR3C1 MSTN GDF11	1.24e-03	275	59	4	20734064
Pubmed	miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network.	FRMPD4 SLIT3	1.27e-03	31	59	2	37816598
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	RELN SLIT3 SEMA6A	1.30e-03	126	59	3	16284245
Pubmed	The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence.	RELN SEMA6A	1.62e-03	35	59	2	20943929
Interaction	PCDHA10 interactions	RELN PCDHA11 PCDHA10 PCDHA3	4.35e-07	22	58	4	int:PCDHA10
Interaction	PCDHA6 interactions	RELN PCDHA10 PCDHA3	1.88e-06	9	58	3	int:PCDHA6
Interaction	PCDHA11 interactions	PCDHA11 PCDHA10 PCDHA3	2.12e-05	19	58	3	int:PCDHA11
Interaction	BRD1 interactions	MAP1A SQSTM1 LRP1 PEX6 KAT6B ZNF687 CPNE7	5.66e-05	344	58	7	int:BRD1
Interaction	RELN interactions	RELN SQSTM1 PCDHA10	6.30e-05	27	58	3	int:RELN
Interaction	SMAD1 interactions	STARD13 IRF2BP1 SQSTM1 GDF6 PEX6 HCFC1	6.92e-05	243	58	6	int:SMAD1
Interaction	GAS6 interactions	SQSTM1 PCDHA3 BRICD5 MSTN	7.15e-05	77	58	4	int:GAS6
Cytoband	5q35	SQSTM1 SLIT3	4.04e-04	23	59	2	5q35
Cytoband	5q31	PCDHA11 PCDHA10 PCDHA3	4.49e-04	115	59	3	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHA11 PCDHA10 PCDHA3 NR3C1	5.98e-04	298	59	4	chr5q31
GeneFamily	Clustered protocadherins	PCDHA11 PCDHA10 PCDHA3	3.53e-04	64	39	3	20
Coexpression	NABA_MATRISOME	COL6A2 RELN IL16 GDF6 SLIT3 ADAMTS16 SEMA6A MSTN MUC5AC GDF11 HCFC1	1.33e-05	1008	59	11	MM17056
Coexpression	NABA_MATRISOME	COL6A2 RELN IL16 GDF6 SLIT3 ADAMTS16 SEMA6A MSTN MUC5AC GDF11 HCFC1	1.56e-05	1026	59	11	M5889
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 SLCO3A1 PTGIR IGDCC4	6.30e-09	191	59	7	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC3B COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR IGDCC4	8.37e-09	199	59	7	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG4B MAP1A CACNA1H GDF11 RYR3 ZNF687	1.88e-08	128	59	6	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR IGDCC4	1.96e-07	190	59	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR IGDCC4	2.08e-07	192	59	6	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR IGDCC4	2.08e-07	192	59	6	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 SLCO3A1 IGDCC4	2.22e-07	194	59	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 SLCO3A1 IGDCC4	2.22e-07	194	59	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN SLIT3 CACNA1H BCAR3 RYR3	1.19e-06	140	59	5	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	IL16 PCDHA11 PCDHA10 PCDHA3 ZNF687	2.22e-06	159	59	5	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	RELN MAP1A PLIN5 LRP1 HSF4	3.65e-06	176	59	5	42541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RELN PLIN5 SEMA6A KLHL14 KRTAP10-4	4.66e-06	185	59	5	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 PTGIR	5.17e-06	189	59	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	5.17e-06	189	59	5	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 SLIT3 ADAMTS16 LRP1 IGDCC4	5.17e-06	189	59	5	d531399749409d614adca13d181830c6e3287508
ToppCell	NS-critical-d_0-4\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPRR3 LRP1 LY6E MUC5AC PTGIR	5.44e-06	191	59	5	769942a6a31c13c583dc38e8a762df2f5c06c2fb
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 SLCO3A1	5.58e-06	192	59	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 FRMPD4 SLIT3 LRP1 IGDCC4	5.58e-06	192	59	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	5.58e-06	192	59	5	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	5.58e-06	192	59	5	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	5.58e-06	192	59	5	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SLIT3 LRP1 SLCO3A1 IGDCC4	5.58e-06	192	59	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	COL6A2 SLIT3 ADAMTS16 IGDCC4 CPNE7	6.01e-06	195	59	5	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 MSTN	6.32e-06	197	59	5	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 COL6A2 SLIT3 LRP1 PCDHA11	6.32e-06	197	59	5	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	ba586690f88fd051f449753bfe7603a2cb431782
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 COL6A2 SLIT3 LRP1 PCDHA11	6.64e-06	199	59	5	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	38ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	06a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	LPS_only-Mesenchymal_fibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	211c3a08f2d484ab7a3368006767289088f0d957
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 SLIT3 LRP1 SLCO3A1 PTGIR	6.64e-06	199	59	5	1a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell	(5)_Fibroblast-F\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL6A2 MAP1A SLIT3 ADAMTS16 LRP1	6.64e-06	199	59	5	1f66db4f502de4a5159cde90fcb3befb26b8d375
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ELAPOR2 COL6A2 SLIT3 ADAMTS16 LY6E	6.80e-06	200	59	5	93c1db92e0e456101f7895867fc8a1fe45298347
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 IL16 SLIT3 LRP1 PTGIR	6.80e-06	200	59	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchyma_COVID-19-Stromal-TX-Mesothelial-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ELAPOR2 COL6A2 SLIT3 ADAMTS16 LY6E	6.80e-06	200	59	5	3be373e9a30e19334e4709e2819fb83cc777d104
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 IL16 SLIT3 LRP1 PTGIR	6.80e-06	200	59	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ELAPOR2 COL6A2 SLIT3 ADAMTS16 LY6E	6.80e-06	200	59	5	46d0ae385e67030bfaf7062bb6b43da5db05b33a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 IL16 SLIT3 LRP1 PTGIR	6.80e-06	200	59	5	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 IL16 SLIT3 LRP1 IGDCC4	6.80e-06	200	59	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 RELN CRYBG1 KLHL14	2.02e-05	121	59	4	056d0f0f7a4d1b2d38b83647bbe4468b7c959ce6
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 RELN GDF6 KLHL14	2.60e-05	129	59	4	f83187c0bb06528127b8d2d56674ab1946846951
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 IFITM10 KLHL14 HSF4	3.02e-05	134	59	4	657ad905b40ec3f82acdef824431b8276d291ef7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS16 STK32C KLHL14 MSTN	3.10e-05	135	59	4	88f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4-Inhibitory_Neuron.Gad1Gad2_Sst.Atp2b4_(Interneuron,_Olm)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PCDHA11 PCDHA3 MSTN	3.12e-05	46	59	3	1259dca3ada3ba697ce50268163bd3b63e3c77bc
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PCDHA11 PCDHA3 MSTN	3.12e-05	46	59	3	457e258b9b38e581b69ff92fc02d552c24d841cf
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4-Inhibitory_Neuron.Gad1Gad2_Sst.Atp2b4_(Interneuron,_Olm)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PCDHA11 PCDHA3 MSTN	3.12e-05	46	59	3	5c1cd6647dd412162273fa01a73f65d62d422038
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLIT3 CACNA1H BCAR3 RYR3	3.20e-05	136	59	4	1f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PCDHA11 KLHL14 RYR3 ZNF687	3.38e-05	138	59	4	05de2cef97c0912fb23f138dd45348f565a14d74
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL6A2 RELN BCAR3 CPNE7	3.48e-05	139	59	4	9e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CASKIN2 PCDHA10 SEMA6A DYNAP	3.58e-05	140	59	4	b9aeb7dda7f377b580dd8a44912f300721437387
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 RELN IFITM10 KLHL14	3.89e-05	143	59	4	24fd24846fbef049af669a57d42fcc18928d2b27
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN FRMPD4 SEMA6A CPNE7	4.93e-05	152	59	4	fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN SEMA6A IFITM10 KLHL14	5.32e-05	155	59	4	5c7b68b59244525e3714806c205a57a2daebf423
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN FRMPD4 SEMA6A CPNE7	5.59e-05	157	59	4	516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	COL6A2 SLIT3 MSTN PTGIR	5.88e-05	159	59	4	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32C IFITM10 HSF4 CPNE7	5.88e-05	159	59	4	d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32C IFITM10 HSF4 CPNE7	5.88e-05	159	59	4	da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNAP STK32C IFITM10 HSF4	6.02e-05	160	59	4	8590281165eab6514a9f6a022b900d4c222c1044
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL6A2 SLIT3 HCFC1 RYR3	6.17e-05	161	59	4	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	Control-Mast_cells-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	CACNA1H IFITM10 KLHL14 PTGIR	6.17e-05	161	59	4	5807ee48f871a3eb24ebf78fd107cf5f2a4ec846
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 RELN IFITM10 KLHL14	6.17e-05	161	59	4	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 LY6E KLHL14 CPNE7	6.17e-05	161	59	4	b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B DUSP16 LRP1 CACNA1H	6.17e-05	161	59	4	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL6A2 LRP1 PCDHA3 RYR3	6.47e-05	163	59	4	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A2 SLIT3 CACNA1H MUC5AC	6.78e-05	165	59	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 SLIT3 MUC5AC CPNE7	7.11e-05	167	59	4	805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 SLIT3 MUC5AC CPNE7	7.11e-05	167	59	4	31cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 SLIT3 MUC5AC CPNE7	7.11e-05	167	59	4	3acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLIT3 CACNA1H RYR3 CPNE7	7.27e-05	168	59	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SLIT3 ADAMTS16 LRP1	7.44e-05	169	59	4	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SLIT3 ADAMTS16 LRP1	7.44e-05	169	59	4	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SLIT3 ADAMTS16 LRP1	7.44e-05	169	59	4	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	Endothelial-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	RELN FRMPD4 PCDHA3 SEMA6A	7.44e-05	169	59	4	8889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 RELN IFITM10 KLHL14	7.61e-05	170	59	4	8ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	COL6A2 RELN SEMA6A KLHL14	7.79e-05	171	59	4	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPP2 SQSTM1 SPRR3 DYNAP	7.97e-05	172	59	4	6ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD13 ELAPOR2 RELN PLIN5	8.15e-05	173	59	4	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A2 SLIT3 CACNA1H MUC5AC	8.15e-05	173	59	4	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CD24\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL6A2 SLIT3 ADAMTS16 CPNE7	8.33e-05	174	59	4	3e29d620b7b4ab1915ddac70ee5a50d09072292b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 SLCO3A1 MSTN PTGIR	8.52e-05	175	59	4	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BCAR3 RYR3 IGDCC4 CPNE7	9.10e-05	178	59	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 SLIT3 CACNA1H PTGIR	9.29e-05	179	59	4	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	STARD13 SLIT3 SLCO3A1 GDF11	9.29e-05	179	59	4	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT3 LRP1 PTGIR IGDCC4	9.50e-05	180	59	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	STARD13 CASKIN2 LINC00472 SEMA6A	9.50e-05	180	59	4	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP1A DUSP16 SLCO3A1 CRYBG1	9.50e-05	180	59	4	d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TPP2 DUSP16 CRYBG1 PTGIR	9.50e-05	180	59	4	5bf5878be3230d38c8e65fb954f326d567e1b520
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 MAP1A SLIT3 LRP1	9.70e-05	181	59	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 MAP1A SLIT3 LRP1	9.70e-05	181	59	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 COL6A2 SLIT3 LRP1	9.91e-05	182	59	4	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 COL6A2 SLIT3 LRP1	9.91e-05	182	59	4	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 GDF6 SLIT3 PTGIR	9.91e-05	182	59	4	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 GDF6 SLIT3 PTGIR	9.91e-05	182	59	4	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	PLEKHG4B COL6A2 SLIT3 RYR3	9.91e-05	182	59	4	ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FRMPD4 ADAMTS16 RYR3	1.03e-04	184	59	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL6A2 IL16 SLIT3 IGDCC4	1.03e-04	184	59	4	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FRMPD4 ADAMTS16 RYR3	1.03e-04	184	59	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FRMPD4 ADAMTS16 RYR3	1.03e-04	184	59	4	2b19a8c5f823e00812908b23e66bb4e563278aff
Disease	vertebral hypersegmentation and orofacial anomalies (implicated_via_orthology)	MSTN GDF11	3.93e-06	2	59	2	DOID:0070418 (implicated_via_orthology)
Disease	1,5 anhydroglucitol measurement	PCDHA11 PCDHA10 PCDHA3	2.67e-05	29	59	3	EFO_0008009
Disease	Osteitis Deformans	SQSTM1 ZNF687	1.40e-04	9	59	2	C0029401
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	SLIT3 LRP1	2.56e-04	12	59	2	DOID:3827 (implicated_via_orthology)
Disease	hypothyroidism (biomarker_via_orthology)	RELN MAP1A MSTN	5.59e-04	80	59	3	DOID:1459 (biomarker_via_orthology)
Disease	visceral adipose tissue measurement, body mass index	PCDHA11 PCDHA10 PCDHA3	7.14e-04	87	59	3	EFO_0004340, EFO_0004765
Disease	chronic obstructive pulmonary disease (is_marker_for)	IL16 NR3C1 MUC5AC	9.80e-04	97	59	3	DOID:3083 (is_marker_for)
Disease	Major Depressive Disorder	RELN SLIT3 LRP1 NR3C1	1.43e-03	243	59	4	C1269683
Disease	susceptibility to rheumatic fever measurement	RELN RYR3	1.44e-03	28	59	2	EFO_0008416
Disease	muscular atrophy (biomarker_via_orthology)	NR3C1 MSTN	1.54e-03	29	59	2	DOID:767 (biomarker_via_orthology)
Disease	pulse pressure measurement	FNDC3B SLIT3 LRP1 NADK PCDHA11 PCDHA10 PCDHA3 NEK9 HCFC1	1.69e-03	1392	59	9	EFO_0005763
Disease	Unipolar Depression	RELN SLIT3 LRP1 NR3C1	1.81e-03	259	59	4	C0041696
Disease	Mental Retardation, X-Linked 1	FRMPD4 HCFC1	1.88e-03	32	59	2	C2931498

Protein segments in the cluster

Peptide	Gene	Start	Entry
CCAERPKPGPTGVKT	BRICD5	6	Q6PL45
CKLPPQSSGVDTSPC	BCAR3	346	O75815
VTGLVPCKVSACPPS	ADAMTS16	916	Q8TE57
SCQLKSPCPLGASPG	IGDCC4	1226	Q8TDY8
CSPTTCSPLSPGKGA	KCTD19	261	Q17RG1
SSPPTCSVKSPQGCV	KAT6B	1741	Q8WYB5
CLPGFPGAPCAIKIS	HCFC1	1886	P51610
PTEGACAPGKPTLVC	PCDHA11	726	Q9Y5I1
DCGPGKPTLVCSSAV	PCDHA3	731	Q9Y5H8
LCQGPSLASKPVPCS	KIAA0100	241	Q14667
GPKLGTCPSRPSCSM	KCNK18	211	Q7Z418
PPTSGGFLKLSKPCC	MAP1A	26	P78559
VTCAGKGTPLTPPAC	NEK9	876	Q8TD19
KGTPLTPPACACSSL	NEK9	881	Q8TD19
GVCGPSPPCITTVSV	KRT85	86	P78386
LLSPSGPVCTCPNGK	LRP1	4161	Q07954
HGPCPVTTFGPKACV	NADK	66	O95544
PPGCGKTTVVAAACS	PEX6	471	Q13608
CAQTPCIPKEGASPT	IL16	1011	Q14005
TATTGPPPKLCLVCS	NR3C1	411	P04150
CETPKGCPVTSTPVT	MUC5AC	4051	P98088
PGAGTAPKPVSVACT	CASKIN2	1096	Q8WXE0
AGVISVPSKCPAGTC	ELAPOR2	846	A8MWY0
PQCLPADPKCSGSVS	RELN	2791	P78509
CSAAPTEGACGPVKP	PCDHA10	721	Q9Y5I2
PQIPATCEPGKVCGA	LINC00472	51	Q9H8W2
AGPACVTVILPSCVP	KLHL14	611	Q9P2G3
CATPVESPLCPSLGK	FRMPD4	1231	Q14CM0
TTAAGPPGQCKAPCI	FNDC3B	761	Q53EP0
ATPGGLPAPCASKVE	CPNE7	11	Q9UBL6
CFPGLCEGKSTLVPT	DUSP16	131	Q9BY84
CYKVSCLEIPGPSGP	COL6A2	246	P12110
GSAGPCCTPTKMSPI	GDF11	366	O95390
PAGSPKGCFACVSKP	IFITM10	66	A6NMD0
TPPICSFTKGECHVP	CFHR5	136	Q9BXR6
GSSCPTPAKFNTCPL	HSF4	216	Q9ULV5
SLSKTCSPACPIPEG	LY6E	66	Q16553
CKPVGSVPICSGASS	KRTAP10-4	281	P60372
PCLSAMGCPPGATFK	CRYBG1	1476	Q9Y4K1
PSPPAGTLTCELKSC	CACNA1H	686	O95180
ECVTVKPGTPSPACP	DYNAP	156	Q8N1N2
CPSGDKCPLVGSSVP	IRF2BP1	546	Q8IU81
DPGSTPPSCCVPTKL	GDF6	411	Q6KF10
PPACRKGLPCSGKSS	STARD13	316	Q9Y3M8
TVVPGKCPSPGCQEA	SLCO3A1	521	Q9UIG8
NPRGSAGPCCTPTKM	MSTN	331	O14793
PSSCCSDPSKPGGNV	SQSTM1	286	Q13501
PGCTKVPEPGCTKVP	SPRR3	56	Q9UBC9
VPEPGCTKVPEPGCT	SPRR3	61	Q9UBC9
SALPMCGPICPSAGS	STK32C	471	Q86UX6
LPPQSLGVSPGCKSC	SLIT3	1321	O75094
ESGPRPTATPCGCVK	TRMO	6	Q9BU70
PTATPCGCVKPALET	TRMO	11	Q9BU70
PSAPVGKEGSCVPLS	PTGIR	336	P43119
ENLPPSTGPCCTKVT	RYR3	3151	Q15413
TPNCVPVEGPGCTKE	PLEKHG4B	121	Q96PX9
VPKPRPGCCAGSSSL	SEMA6A	361	Q9H2E6
PKSGEVTPSCPLLCE	TPP2	831	P29144
SPLPASGGPLTCKVC	ZNF687	1191	Q8N1G0
KSPKLCNPTGPTVSC	SCN11A	731	Q9UI33
CGVTPTAPACPGKVH	PLIN5	246	Q00G26
KGTVPVPEGCSPCSV	TRIM56	541	Q9BRZ2
PPPCQKAPSGLVTSC	GARIN5B	396	Q8N5Q1