Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin activating enzyme activity

UBA1 NAE1 UBA6

3.21e-0641873GO:0004839
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ABCC1 DDX19A DNAH3 RHOBTB3 DHX38 NVL PEX6 MSH2 DHX30 UBA1 NAE1 DNAH17 DDX25 UBA6 DNAH6 TAP2 SNRNP200 ACSS3

5.36e-0661418719GO:0140657
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH3 DNAH17 DNAH6

2.06e-05181874GO:0008569
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

SUCLA2 UBA1 NAE1 UBA6 ACSS3

3.89e-05411875GO:0016877
GeneOntologyMolecularFunctionubiquitin-like modifier activating enzyme activity

UBA1 NAE1 UBA6

9.24e-05101873GO:0008641
GeneOntologyMolecularFunctionacyl-CoA binding

PANK3 ACADL PANK1 SCP2

9.48e-05261874GO:0120227
GeneOntologyMolecularFunctionphosphatidylinositol transfer activity

PITPNM2 PITPNM1 SCP2

1.26e-04111873GO:0008526
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH3 DNAH17 DNAH6

1.28e-04281874GO:0051959
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC1 DDX19A DNAH3 RHOBTB3 DHX38 NVL PEX6 MSH2 DHX30 DDX25 DNAH6 TAP2 SNRNP200

2.76e-0444118713GO:0016887
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH3 DNAH17 DNAH6

3.86e-04371874GO:0045505
GeneOntologyMolecularFunctionfibronectin binding

SFRP2 TNC CCDC80 TNFAIP6

4.29e-04381874GO:0001968
GeneOntologyMolecularFunctionpantothenate kinase activity

PANK3 PANK1

5.17e-0441872GO:0004594
GeneOntologyMolecularFunctionacetyl-CoA binding

PANK3 PANK1

5.17e-0441872GO:1905502
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ANKK1 PRPSAP2 FLT4 PANK3 PDGFRL GRK6 TEX14 PANK1 PTK6 POLR3G IGF1R CSF1R COQ8A PIK3C2B UBA6 MAP3K15 PIP4K2C MAPK10 ART5 IPMK

5.24e-0493818720GO:0016772
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

PITPNM2 PITPNM1 SCP2

8.19e-04201873GO:0008525
GeneOntologyMolecularFunctionRNA helicase activity

DDX19A DHX38 DHX30 DDX25 SNRNP200

8.29e-04781875GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX19A DHX38 DHX30 DDX25 SNRNP200

9.30e-04801875GO:0008186
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

ANKK1 FLT4 PANK3 PDGFRL GRK6 TEX14 PANK1 PTK6 IGF1R CSF1R COQ8A PIK3C2B MAP3K15 PIP4K2C MAPK10 IPMK

1.07e-0370918716GO:0016773
GeneOntologyMolecularFunctionubiquitin ligase complex scaffold activity

CUL2 DDB1

1.28e-0361872GO:0160072
GeneOntologyMolecularFunctionligase activity

ACACA SUCLA2 GMPS UBA1 NAE1 UBA6 ACSS3

1.29e-031741877GO:0016874
GeneOntologyBiologicalProcessinositol trisphosphate metabolic process

PLCB1 SCP2 PLCB3 IPMK

1.33e-05171844GO:0032957
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH3 DNAH17 CFAP70 DNAH6

2.49e-06251875GO:0005858
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH3 DNAH6

8.07e-05101873GO:0036156
GeneOntologyCellularComponentdynein complex

DNHD1 DNAH3 DNAH17 CFAP70 DNAH6

1.20e-04541875GO:0030286
GeneOntologyCellularComponentpostsynaptic Golgi apparatus

ZDHHC17 MAPK10

2.37e-0431872GO:0150051
GeneOntologyCellularComponentmatrilin complex

MATN2 MATN4

4.72e-0441872GO:0120216
GeneOntologyCellularComponenttenascin complex

TNC TNN

4.72e-0441872GO:0090733
MousePhenoincreased circulating LDL cholesterol level

LDLRAP1 CT45A6 CT45A1 CT45A10 CT45A2 CT45A7 SLC3A1 CT45A9 CT45A3 SCP2

1.22e-088014910MP:0000182
MousePhenoabnormal circulating LDL cholesterol level

LDLRAP1 CT45A6 CT45A1 CT45A10 UBE3B CT45A2 CT45A7 SLC3A1 CT45A9 PLA2G12B CT45A3 SCP2

1.68e-0716314912MP:0000181
MousePhenoabnormal circulating non-HDL cholesterol level

LDLRAP1 CT45A6 CT45A1 CT45A10 UBE3B CT45A2 CT45A7 SLC3A1 CT45A9 PLA2G12B CT45A3 SCP2

4.93e-0718014912MP:0020151
DomainINT_SG_DDX_CT_C

CT45A1 CT45A10 CT45A7 CT45A9 CT45A3

4.94e-0981855PF15300
DomainINT_SG_DDX_CT_C

CT45A1 CT45A10 CT45A7 CT45A9 CT45A3

4.94e-0981855IPR029307
DomainPolyA

PABPC4 UBR5 PABPC1L

9.42e-0651853SM00517
Domain-

PABPC4 UBR5 PABPC1L

9.42e-06518531.10.1900.10
DomainPABP

PABPC4 UBR5 PABPC1L

9.42e-0651853PF00658
DomainPABC

PABPC4 UBR5 PABPC1L

9.42e-0651853PS51309
DomainPABP_HYD

PABPC4 UBR5 PABPC1L

9.42e-0651853IPR002004
DomainSecurin_separation-inh_met

PTTG1 PTTG2

9.76e-0521852IPR018008
DomainSecurin_separation_inhibitor

PTTG1 PTTG2

9.76e-0521852IPR006940
DomainSecurin

PTTG1 PTTG2

9.76e-0521852PF04856
DomainThiF_NAD_FAD-bd

UBA1 NAE1 UBA6

1.09e-04101853IPR000594
DomainThiF

UBA1 NAE1 UBA6

1.09e-04101853PF00899
DomainATP-grasp_succ-CoA_synth-type

ACLY SUCLA2

2.91e-0431852IPR013650
DomainE1_4HB

UBA1 UBA6

2.91e-0431852PF16191
DomainE1_FCCH

UBA1 UBA6

2.91e-0431852PF16190
DomainUBQ-activ_enz_E1

UBA1 UBA6

2.91e-0431852IPR018075
DomainUBA_e1_C

UBA1 UBA6

2.91e-0431852SM00985
DomainPLC-beta_CS

PLCB1 PLCB3

2.91e-0431852IPR009535
DomainUb-activating_enz_E1_C

UBA1 UBA6

2.91e-0431852IPR018965
DomainMRG

MORF4L2 MORF4L1

2.91e-0431852PS51640
DomainSucc-CoA_synthase_bsu_CS

ACLY SUCLA2

2.91e-0431852IPR017866
DomainMRG_dom

MORF4L2 MORF4L1

2.91e-0431852IPR026541
DomainPLC-beta_C

PLCB1 PLCB3

2.91e-0431852PF08703
DomainATP-grasp_2

ACLY SUCLA2

2.91e-0431852PF08442
DomainPLC-beta_C

PLCB1 PLCB3

2.91e-0431852IPR014815
DomainE1_4HB

UBA1 UBA6

2.91e-0431852IPR032420
DomainE1_FCCH

UBA1 UBA6

2.91e-0431852IPR032418
DomainE1_UFD

UBA1 UBA6

2.91e-0431852PF09358
DomainSUCCINYL_COA_LIG_3

ACLY SUCLA2

2.91e-0431852PS01217
DomainDUF1154

PLCB1 PLCB3

2.91e-0431852PF06631
DomainDynein_HC_stalk

DNHD1 DNAH3 DNAH6

3.21e-04141853IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH3 DNAH6

3.21e-04141853IPR013602
DomainDHC_N2

DNHD1 DNAH3 DNAH6

3.21e-04141853PF08393
DomainMT

DNHD1 DNAH3 DNAH6

3.21e-04141853PF12777
DomainDHC_fam

DNHD1 DNAH3 DNAH6

3.99e-04151853IPR026983
DomainDynein_heavy

DNHD1 DNAH3 DNAH6

3.99e-04151853PF03028
DomainDynein_heavy_dom

DNHD1 DNAH3 DNAH6

3.99e-04151853IPR004273
DomainRmlC_Cupin

CT45A1 CT45A2 CT45A3

4.87e-04161853IPR011051
DomainCoA_ligase

ACLY SUCLA2

5.78e-0441852IPR005811
Domain-

GTF2IRD2B GTF2IRD2

5.78e-04418523.90.1460.10
DomainG8_domain

PKHD1L1 PKHD1

5.78e-0441852IPR019316
DomainPLC-beta

PLCB1 PLCB3

5.78e-0441852IPR016280
DomainMRG

MORF4L2 MORF4L1

5.78e-0441852IPR008676
DomainG8

PKHD1L1 PKHD1

5.78e-0441852PS51484
DomainSuccinyl-CoA_synth-like

ACLY SUCLA2

5.78e-0441852IPR016102
DomainMatrilin_ccoil

MATN2 MATN4

5.78e-0441852SM01279
DomainType_II_PanK

PANK3 PANK1

5.78e-0441852IPR004567
DomainG8

PKHD1L1 PKHD1

5.78e-0441852SM01225
Domain-

UBA1 UBA6

5.78e-04418521.10.3240.10
Domain-

MATN2 MATN4

5.78e-04418521.20.5.30
DomainMatrilin_ccoil

MATN2 MATN4

5.78e-0441852PF10393
DomainG8

PKHD1L1 PKHD1

5.78e-0441852PF10162
DomainFumble

PANK3 PANK1

5.78e-0441852PF03630
DomainLigase_CoA

ACLY SUCLA2

5.78e-0441852PF00549
DomainGTF2I

GTF2IRD2B GTF2IRD2

5.78e-0441852PS51139
DomainMatrilin_coiled-coil_trimer

MATN2 MATN4

5.78e-0441852IPR019466
DomainGTF2I

GTF2IRD2B GTF2IRD2

5.78e-0441852PF02946
DomainMRG

MORF4L2 MORF4L1

5.78e-0441852PF05712
DomainGTF2I

GTF2IRD2B GTF2IRD2

5.78e-0441852IPR004212
Domain-

ACLY SUCLA2

5.78e-04418523.40.50.261
DomainAAA

ABCC1 DNAH3 NVL PEX6 DNAH6 TAP2 SNRNP200

5.87e-041441857SM00382
DomainAAA+_ATPase

ABCC1 DNAH3 NVL PEX6 DNAH6 TAP2 SNRNP200

5.87e-041441857IPR003593
Domain-

ACACA ACLY SUCLA2

6.99e-041818533.30.470.20
DomainDEAD/DEAH_box_helicase_dom

DDX19A DHX38 DHX30 DDX25 SNRNP200

7.87e-04731855IPR011545
DomainDEAD

DDX19A DHX38 DHX30 DDX25 SNRNP200

7.87e-04731855PF00270
DomainGrowth_fac_rcpt_

FAT4 FRAS1 TNC MATN2 MATN4 IGF1R TNN

9.41e-041561857IPR009030
DomainUBIQUITIN_ACTIVAT_1

UBA1 UBA6

9.57e-0451852PS00536
DomainUBA_E1_Cys

UBA1 UBA6

9.57e-0451852IPR019572
DomainIP_trans

PITPNM2 PITPNM1

9.57e-0451852PF02121
DomainPABP_1234

PABPC4 PABPC1L

9.57e-0451852IPR006515
DomainUBIQUITIN_ACTIVAT_2

UBA1 UBA6

9.57e-0451852PS00865
DomainUBA_e1_thiolCys

UBA1 UBA6

9.57e-0451852PF10585
Domain-

CPLANE2 DNHD1 ABCC1 DDX19A DNAH3 CACNB3 GNL3L RHOBTB3 DHX38 NVL PEX6 MSH2 DHX30 DDX25 DNAH6 TAP2 SNRNP200

1.23e-03746185173.40.50.300
DomainLNS2

PITPNM2 PITPNM1

1.43e-0361852IPR013209
DomainPI_transfer

PITPNM2 PITPNM1

1.43e-0361852IPR001666
DomainLNS2

PITPNM2 PITPNM1

1.43e-0361852SM00775
DomainPbH1

PKHD1L1 PKHD1

1.43e-0361852SM00710
DomainDDHD

PITPNM2 PITPNM1

1.43e-0361852PF02862
DomainDDHD

PITPNM2 PITPNM1

1.43e-0361852PS51043
DomainDDHD_dom

PITPNM2 PITPNM1

1.43e-0361852IPR004177
DomainLNS2

PITPNM2 PITPNM1

1.43e-0361852PF08235
DomainUBQ/SUMO-activ_enz_E1-like

UBA1 UBA6

1.43e-0361852IPR000011
DomainLNS2/PITP

PITPNM2 PITPNM1

1.43e-0361852IPR031315
DomainPbH1

PKHD1L1 PKHD1

1.43e-0361852IPR006626
DomainDDHD

PITPNM2 PITPNM1

1.43e-0361852SM01127
DomainPkinase_Tyr

ANKK1 FLT4 TEX14 PTK6 IGF1R CSF1R

1.81e-031291856PF07714
DomainZnF_UBR1

UBR4 UBR5

1.98e-0371852SM00396
DomainZF_UBR

UBR4 UBR5

1.98e-0371852PS51157
Domainzf-UBR

UBR4 UBR5

1.98e-0371852PF02207
DomainZnf_UBR

UBR4 UBR5

1.98e-0371852IPR003126
DomainHECT

HECTD3 UBE3B UBR5

2.35e-03271853PF00632
DomainHECTc

HECTD3 UBE3B UBR5

2.35e-03271853SM00119
DomainHECT_dom

HECTD3 UBE3B UBR5

2.35e-03271853IPR000569
DomainIPT

PKHD1L1 PKHD1 PLXNB1

2.35e-03271853SM00429
DomainHECT

HECTD3 UBE3B UBR5

2.35e-03271853PS50237
DomainSer-Thr/Tyr_kinase_cat_dom

ANKK1 FLT4 TEX14 PTK6 IGF1R CSF1R

2.54e-031381856IPR001245
DomainTyr_kinase_rcpt_3_CS

FLT4 CSF1R

2.63e-0381852IPR001824
DomainRECEPTOR_TYR_KIN_III

FLT4 CSF1R

2.63e-0381852PS00240
DomainPectin_lyase_fold/virulence

PKHD1L1 PKHD1

2.63e-0381852IPR011050
DomainCalx_beta

FRAS1 ADGRV1

2.63e-0381852SM00237
Pubmed

Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

CT45A6 CT45A1 CT45A10 CT45A2 CT45A7 CT45A9 CT45A8 CT45A3 CT45A5

1.74e-1715190915905330
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

IPO5 PRPSAP2 CUL2 DDX19A RELCH ACACA HECTD3 GON7 ACLY UBR4 DHX38 PABPC4 ETFA PSMD9 MSH2 RRM1 GDI2 DDB1 ARPC3 GMPS UBA1 TSR1 NAE1 UBA6 PUS1 PLCB3 NUDCD1 PLEC COG5 SNRNP200 FKBP5 ALDH7A1

1.85e-1114551903222863883
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

IPO5 CUL2 DDX19A GNL3L ACACA ACLY UBR4 PABPC4 ETFA FASTKD5 PSMD9 MSH2 RRM1 SUCLA2 GDI2 DDB1 ARPC3 SLC1A5 DHX30 GMPS UBA1 COQ8A UBR5 NAE1 FBXO7 TMED9 SNRNP200 FKBP5

2.95e-1012571902837317656
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DDX19A ACACA RBBP6 ACLY UBR4 DHX38 PABPC4 ETFA FASTKD5 COPG2 MSH2 SUCLA2 SLC1A5 BDH1 DHX30 GMPS TRMT10C FAM111A TSR1 FBXO7 PUS1 TMED9 PLEC PIP4K2C SNRNP200 FKBP5

1.63e-0813181902630463901
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

IPO5 PRPSAP2 ACACA ACLY UBR4 DHX38 PABPC4 EXOSC3 NIPSNAP2 PSMD9 MSH2 RRM1 DDB1 ARPC3 DHX30 GMPS TRMT10C UBA1 UBR5 TSR1 MORF4L2 MORF4L1 UBA6 PLCB3 PLEC PIP4K2C SNRNP200

1.68e-0814151902728515276
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 ACACA MAP1B ACLY UBR4 DHX38 PABPC4 NVL COPG2 MSH2 GDI2 DDB1 DHX30 GMPS UBR5 TSR1 PLEC SNRNP200

2.36e-086531901822586326
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

IPO5 PRPSAP2 CUL2 ACACA RBBP6 ACLY UBR4 PABPC4 RNF149 EXOSC3 CPD PSMD9 RRM1 SLC1A5 DHX30 GMPS TRMT10C UBA1 UBR5 TSR1 MORF4L2 MORF4L1 ANTXR1 TMED9 ALDH7A1

4.95e-0812971902533545068
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

ABCC1 HECTD3 PABPC4 FASTKD5 DHX30 PLXDC2 COQ8A MORF4L2 MORF4L1 COG5 SNRNP200 FKBP5

5.99e-082831901221903422
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

IPO5 PRPSAP2 CUL2 MAP1B ACLY PABPC4 EXOSC3 PSMD9 MSH2 GDI2 DDB1 SLC1A5 DHX30 GMPS TRMT10C UBA1 UBR5 TSR1 MORF4L2 NAE1 MORF4L1 TMED9 SNRNP200 FKBP5 ALDH7A1

8.58e-0813351902529229926
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

IPO5 PRPSAP2 ACACA MAP1B ACLY UBR4 PABPC4 ETFA EXOSC3 COPG2 PSMD9 GDI2 DDB1 ARPC3 GMPS UBA1 UBR5 TSR1 NAE1 PLEC SNRNP200 FKBP5 ALDH7A1

9.12e-0811491902335446349
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

IPO5 CUL2 KDM5B MAP1B DHX38 USP29 NIPSNAP2 CNKSR2 MSH2 CEP192 SUCLA2 SLC1A5 GMPS TRMT10C UBR5 NAE1 FBXO7 NUDCD1 PLEC SNRNP200 FKBP5

1.71e-0710051902119615732
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

IPO5 DNHD1 DDX19A GNL3L ACACA ACLY PCLO UBR4 DHX38 PABPC4 ETFA FASTKD5 MSH2 SUCLA2 GDI2 DDB1 SLC1A5 DHX30 TRMT10C UBA1 TSR1 UBA6 PUS1 TMED9 SNRNP200

2.91e-0714251902530948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IPO5 PITPNM2 MYADM ACADL MAP1B TNC ACLY PCLO PABPC4 NIPSNAP2 CNKSR2 SUCLA2 GDI2 DDB1 ARPC3 DHX30 PITPNM1 UBA1 MORF4L2 TMED9 PLEC PIP4K2C DNAH6 SNRNP200 ALDH7A1

3.15e-0714311902537142655
Pubmed

Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.

CUL2 FOXN2 ACLY UBR4 UBA1 UBA6

3.20e-0750190617550899
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IPO5 CUL2 ABCC1 GNL3L MAP1B UBR4 PABPC4 ETFA EXOSC3 FASTKD5 COPG2 MSH2 RRM1 SUCLA2 DDB1 ARPC3 SLC1A5 TRMT10C COQ8A UBR5 TMED9 COG5 TAP2 SNRNP200 FKBP5

3.54e-0714401902530833792
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

IPO5 CUL2 MAP1B ACLY MSH2 ADGRV1 GDI2 DDB1 GMPS TRMT10C UBA1 NAE1 FBXO7 SNRNP200

6.69e-074951901428581483
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

IPO5 ACACA ACLY ETFA DDB1 SLC1A5 COQ8A UBR5 SNRNP200

1.52e-06197190931620119
Pubmed

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

CUL2 UBE3B UBR4 PSMD9 UBR5 FBXO7

1.70e-0666190624811749
Pubmed

Defining the membrane proteome of NK cells.

DOCK2 IPO5 ABCC1 DDX19A GNL3L ACLY GRK6 UBR4 DHX38 RNF149 NVL CPD MSH2 RBM23 ARPC3 SLC1A5 UBR5 SCP2 COG5 TAP2 FKBP5

1.91e-0611681902119946888
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 CACNB3 GNL3L ACACA MAP1B PCDH11Y EXOSC3 CPD CEP192 SYT2 ADGRV1 SUCLA2 BDH1 PTK6 GMPS IGF1R FAM111A PLXDC2 COQ8A UBA6 SCP2 ANTXR1 CATSPERG FKBP5

2.26e-0614891902428611215
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DOCK2 IPO5 ACACA ACADL ACLY PCLO UBR4 ETFA COPG2 GDI2 DDB1 ARPC3 SLC1A5 ARID1B PLEC SNRNP200 ALG13

2.44e-068071901730575818
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CUL2 FRAS1 GNL3L MAP1B HECTD3 RHOBTB3 UBE3B DHX38 PEX6 ZDHHC17 COQ8A TSR1 ANTXR1 PLCB3 PLXNB1

3.28e-066501901538777146
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

IPO5 MAP1B HECTD3 ACLY UBR4 PABPC4 FASTKD5 COPG2 CPD DDB1 SLC1A5 UBR5 TMED9 SNRNP200 ALG13

3.73e-066571901536180527
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

IPO5 DDX19A MAP1B ACLY GRK6 PABPC4 ETFA MSH2 DDB1 ARPC3 SLC1A5 DHX30 UBA1 UBR5 UBA6 TMED9 PLEC SCIN SNRNP200

3.88e-0610241901924711643
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PRPSAP2 PITPNM2 RELCH ACACA ACADL MAP1B PCLO UBR4 ETFA NIPSNAP2 CNKSR2 SUCLA2 BDH1 PITPNM1 GMPS TRMT10C UBA1 POMGNT2 PLCB1 PLEC

4.84e-0611391902036417873
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRPSAP2 CT45A6 CT45A1 CT45A10 RHOBTB3 UBE3B PABPC4 CT45A2 CDH23 ARPC3 CT45A7 POLR3G CT45A9 PITPNM1 ARID1B CT45A3 DNAH17 FBXO7 PABPC1L MAPK10 ALG13

4.94e-0612421902130973865
Pubmed

Functional proteomics mapping of a human signaling pathway.

SOX5 FLT4 RBBP6 UBR4 PABPC4 PEX6 DDB1 DHX30 ARID1B UBR5 UBA6 PLAG1 PLEC BRD1

5.23e-065911901415231748
Pubmed

Network organization of the human autophagy system.

IPO5 CUL2 ACACA MAP1B ETFA NIPSNAP2 GDI2 DDB1 GMPS MAP3K15 FKBP5 ALDH7A1

5.78e-064371901220562859
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

GNL3L ACLY PABPC4 COPG2 CEP192 RRM1 DDB1 DHX30 GTF2IRD2B SEPSECS TRMT10C ARID1B UBA1 TSR1 MORF4L2 GTF2IRD2 PABPC1L ENO3 SNRNP200 FKBP5

5.80e-0611531902029845934
Pubmed

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

CUL2 UBA1 NAE1 UBA6

7.04e-0623190419250909
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

DDB1 UBR5 MORF4L2 MORF4L1

7.04e-0623190422038470
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

IPO5 CUL2 FLT4 PABPC4 COPG2 RRM1 GDI2 DDB1 DHX30 TRMT10C UBR5 TSR1 MORF4L2 MORF4L1 TMED9 SCIN SNRNP200 FKBP5

7.14e-069711901833306668
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

CUL2 FLT4 HECTD3 GRK6 DNAAF9 PTK6 PRDM1 IGF1R CSF1R GTF2IRD2 MAP3K15

7.15e-063721901122939624
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

DDX19A ACLY PABPC4 ETFA CCDC80 RBM23 SLC1A5 DHX30 TRMT10C UBA1 SCP2 TMED9 PLEC PIP4K2C ENO3 ALDH7A1

7.48e-067861901629128334
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

PRPSAP2 DDX19A ACACA MAP1B UBR4 DHX38 EXOSC3 COPG2 MSH2 SUCLA2 ARPC3 DHX30 UBR5 SNRNP200 FKBP5

8.51e-067041901529955894
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

DDX19A ACACA UBR4 PABPC4 COPG2 MSH2 SUCLA2 GDI2 DDB1 DHX30 UBA1 UBR5 PUS1

8.57e-065341901335032548
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

IPO5 PRPSAP2 DDX19A ACLY PABPC4 ETFA COPG2 MSH2 DHX30 TRMT10C ALG13

9.39e-063831901129331416
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

IPO5 ABCC1 UBR4 PABPC4 ETFA FASTKD5 DDB1 TSR1 AGMAT TMED9 NUDCD1 PLEC HEPHL1 SNRNP200 ALDH7A1

9.57e-067111901533022573
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

MAP1B ACLY DHX38 PABPC4 ETFA GDI2 DDB1 RBM23 ARPC3 SLC1A5 PTK6 DHX30 GMPS UBA1 SNRNP200

1.01e-057141901528302793
Pubmed

A protein interaction landscape of breast cancer.

IPO5 CUL2 ABCC1 UBR4 PABPC4 MSH2 DHX30 ARID1B UBA1 UBR5 MORF4L1 PIP4K2C TAP2 FKBP5

1.15e-056341901434591612
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

IPO5 ACACA ACLY UBR4 COPG2 MSH2 RRM1 DDB1 DHX30 GMPS UBA1 COQ8A PLEC SNRNP200

1.24e-056381901433239621
Pubmed

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.

UBR4 DDB1 UBR5

1.32e-059190317855541
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

IPO5 RELCH ACACA ACLY UBR4 COPG2 MSH2 DDB1 GMPS UBR5 TSR1

1.37e-053991901137536630
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAM47A DNAH3 FAT4 ACACA ACLY PCLO UBR4 EXOSC3 CT45A2 CT45A9 GMPS CT45A8 PKHD1 PLCB3 SNRNP200

1.43e-057361901529676528
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MAP1B ACLY UBR4 PABPC4 ETFA CCDC80 COPG2 SUCLA2 GDI2 UBA1 UBR5 PABPC1L PLEC TAP2

1.44e-056471901426618866
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

CUL2 UBE3B UBR4 PABPC4 NVL NIPSNAP2 UBA1 UBR5 PIK3C2B UBA6 ANTXR1 PLEC

1.51e-054811901228190767
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

IPO5 ABCC1 MYADM ACACA ACADL ACLY MATN2 ETFA CCDC80 FASTKD5 CPD ZDHHC17 SUCLA2 DDB1 AEBP1 TMED9 PLEC PIP4K2C CATSPERG DNAH6 TAP2 SNRNP200

1.60e-0514511902230550785
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

IPO5 FRAS1 ACACA RBBP6 ACLY DHX38 PABPC4 MSH2 RRM1 DDB1 RBM23 SLC1A5 DHX30 TSR1

1.60e-056531901433742100
Pubmed

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.

ACADL ACLY PCLO ETFA GDI2 BDH1 GMPS ALDH7A1

1.66e-05202190833601422
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DDX19A GNL3L ACACA MAP1B ACLY UBR4 DHX38 EXOSC3 ADNP2 MSH2 RRM1 DDB1 SLC1A5 DHX30 GMPS UBA1 UBR5 PLEC PIP4K2C SNRNP200 ALDH7A1

1.79e-0513531902129467282
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CUL2 ABCC1 ACADL PABPC4 ETFA EXOSC3 NVL FASTKD5 COPG2 PSMD9 SUCLA2 DDB1 SEPSECS UBR5 ALDH7A1

1.90e-057541901533060197
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

ACACA ACLY PABPC4 MSH2 DDB1 DHX30 COQ8A UBR5 SNRNP200

2.05e-05272190925315684
Pubmed

Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.

PTTG1 TNC RRM1 PTTG2

2.12e-0530190416420439
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FRAS1 ACACA CDH23 ADGRV1 NEB SLC2A2 PLEC

2.16e-05152190734299191
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

IPO5 MAP1B UBR4 DHX38 DDB1 ARPC3 GMPS UBA1 PLEC SNRNP200

2.17e-053441901030333137
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CUL2 FRAS1 HECTD3 UBR4 ETFA NVL FASTKD5 CPD CEP192 ZDHHC17 RRM1 SUCLA2 DDB1 SLC1A5 DHX30 TRMT10C UBR5 TSR1 NAE1 UBA6 SNRNP200 FKBP5

2.32e-0514871902233957083
Pubmed

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

MSH2 RRM1 SLC1A5 UBA1 UBA6

2.32e-0562190526508657
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

IPO5 CUL2 DDX19A ACLY UBR4 ETFA CPD MSH2 DDB1 SLC1A5 GMPS SEPSECS TRMT10C UBR5 PUS1 SNRNP200 FKBP5

2.78e-059741901728675297
Pubmed

Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells.

FLT4 TNFSF15

2.97e-052190226096340
Pubmed

Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes.

NEB TNFAIP6

2.97e-05219029427551
Pubmed

Identification and characteristics of a novel E1 like gene nUBE1L in human testis.

UBA1 UBA6

2.97e-052190215202508
Pubmed

The Escherichia coli adherence factor plasmid of enteropathogenic Escherichia coli causes a global decrease in ubiquitylated host cell proteins by decreasing ubiquitin E1 enzyme expression through host aspartyl proteases.

UBA1 UBA6

2.97e-052190222999844
Pubmed

Extracellular matrix changes in corneal opacification vary depending on etiology.

TNC MATN2

2.97e-052190233633437
Pubmed

Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5.

UBA1 UBA6

2.97e-052190232315024
Pubmed

Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain.

SYT2 IPMK

2.97e-052190231221192
Pubmed

Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration.

TNC TNN

2.97e-052190224101721
Pubmed

MrgX is not essential for cell growth and development in the mouse.

MORF4L2 MORF4L1

2.97e-052190215923606
Pubmed

PLAG1-HAS2 fusion in lipoblastoma with masked 8q intrachromosomal rearrangement.

PLAG1 HAS2

2.97e-052190215642402
Pubmed

Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations.

MSH2 SCP2

2.97e-05219027713503
Pubmed

GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

ABCC1 IGF1R

2.97e-052190228266043
Pubmed

Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation.

ACACA ACLY

2.97e-052190223886516
Pubmed

Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters.

PANK3 PANK1

2.97e-052190216040613
Pubmed

The adhesion modulating properties of tenascin-W.

TNC TNN

2.97e-052190222211116
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.97e-052190215388857
Pubmed

The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.

CDH23 ADGRV1

2.97e-052190215820310
Pubmed

Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells.

TNFAIP6 HAS2

2.97e-052190216687630
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

RELCH ACACA UBR4 RBM23 COQ8A UBR5 PIK3C2B PLEC COG5

3.21e-05288190923383273
Pubmed

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

PRPSAP2 ETFA NIPSNAP2 FASTKD5 SUCLA2 DHX30 TRMT10C COQ8A NDUFAF7 FBXO7 ALDH7A1

3.23e-054381901132628020
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

GNL3L ACACA ACLY DHX38 EXOSC3 MSH2 DDB1 SLC1A5 DHX30 TRMT10C UBA1 TSR1 CT45A3 MORF4L1 NUDCD1 PLEC SNRNP200

3.36e-059891901736424410
Pubmed

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.

UBR4 DDB1 UBR5

3.40e-0512190317360488
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC1 MYADM FAT4 FRAS1 MAP1B ACLY MATN2 RNF149 CPD RRM1 DDB1 UBA1 IGF1R POMGNT2 NAE1 ANTXR1 TMED9 TAP2 PLXNB1

3.55e-0512011901935696571
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF536 GNL3L HECTD3 RBBP6 RHOBTB3 ADNP2 PEX6 FASTKD5 DDB1 ARID1B COQ8A UBR5 GFOD1 MORF4L2 MORF4L1 PIP4K2C BRD1 ALG13

4.49e-0511161901831753913
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

IPO5 CUL2 RBBP6 UBR4 DHX38 NVL MSH2 GDI2 DDB1 GMPS UBA1 UBR5 TSR1 NAE1 UBA6 PLEC FKBP5

4.58e-0510141901732416067
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DNHD1 ACLY CNKSR2 ADGRV1 NEB SUCLA2 GDI2 DDB1 ARPC3 SLC3A1 UBA1 CLIC5 PKHD1 CFAP70 PIP4K2C SCIN FKBP5

4.70e-0510161901719056867
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

IPO5 ACACA ACLY DDB1 SNRNP200

4.80e-0572190536376293
Pubmed

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.

IPO5 HECTD3 ACLY NIPSNAP2 DDB1 DHX30 TRMT10C SNRNP200

5.02e-05236190836339263
Pubmed

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

ACLY PABPC4 DDB1 GMPS UBA1 UBR5 SNRNP200

5.30e-05175190725756610
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

IPO5 CUL2 MSH2 DDB1 BDH1 SNRNP200

5.35e-05120190627320910
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH17 DNAH6

5.59e-051419039373155
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

PRPSAP2 MAP1B ACLY UBR4 PABPC4 DDB1 DHX30 UBA1 PUS1 PLEC SNRNP200 ALG13

5.62e-055511901234728620
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ACADL MAOB ETFA NIPSNAP2 FASTKD5 SUCLA2 BDH1 DHX30 TRMT10C COQ8A SUGCT NDUFAF7 UCP3 PUS1 AGMAT ALDH7A1 DMAC1 ACSS3

5.63e-0511361901834800366
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

IPO5 PRPSAP2 MAP1B PABPC4 ETFA ARPC3 SLC1A5 DHX30 TMED9 PLEC FKBP5

5.86e-054681901136042349
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

CUL2 ACACA MAP1B UBR4 ETFA CT45A2 RRM1 SUCLA2 GDI2 DDB1 GMPS TRMT10C UBA1 NAE1 UBA6 SCP2 TMED9 NUDCD1 COG5 ALDH7A1

6.49e-0513671902032687490
Pubmed

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition.

ACLY SUCLA2 GDI2 SLC1A5 UBA1 SCP2 ALDH7A1

6.79e-05182190736225252
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

IPO5 CUL2 MAP1B ACLY UBR4 DHX30 PLEC

6.79e-05182190731067453
Pubmed

GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH.

ACLY UBA1 UBA6

6.96e-0515190331417184
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

DDX19A GNL3L ACACA ETFA COPG2 SUCLA2 DDB1 SLC1A5 GMPS UBA1 COQ8A ENO3

7.13e-055651901233567341
Pubmed

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

UBR4 SYT2 DDB1 UBA1 UBR5

7.50e-0579190527325702
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

IPO5 DDX19A ACACA RBBP6 UBR4 ETFA NVL COPG2 SUCLA2 GMPS UBA1 ENO3 SNRNP200

8.23e-056651901330457570
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CUL2 ACACA ACLY UBR4 DHX38 PABPC4 NIPSNAP2 COPG2 CNKSR2 MSH2 ARPC3 SLC1A5 IGF1R UBR5 TSR1 MORF4L2 NAE1 MORF4L1 SNRNP200

8.60e-0512841901917353931
CytobandEnsembl 112 genes in cytogenetic band chrXq26

CT45A6 CT45A1 CT45A10 CT45A2 CT45A7 CT45A9 CT45A8 CT45A3 CT45A5

4.60e-081711909chrXq26
CytobandXq26.3

CT45A6 CT45A1 CT45A2 CT45A3 CT45A5

9.03e-06671905Xq26.3
CytobandXp22.12

CNKSR2 MAP3K15

4.69e-0481902Xp22.12
GeneFamilyUbiquitin like modifier activating enzymes

UBA1 NAE1 UBA6

2.84e-05101143100
GeneFamilyDyneins, axonemal

DNAH3 DNAH17 DNAH6

1.56e-04171143536
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNM1

5.81e-04611421151
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR4 UBR5

8.11e-0471142785
GeneFamilySolute carriers

SLC35B3 SLC1A5 SLC2A2 SLC3A1 SLC35D1 SLC9C1 UCP3 SLC36A3 SLC44A3

8.91e-043951149752
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT4 IGF1R CSF1R

2.04e-03401143321
GeneFamilyPhospholipases

PLA2G12B PLCB1 PLCB3

2.34e-03421143467
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

MORF4L2 MORF4L1

2.50e-031211421243
GeneFamilyAT-rich interaction domain containing

KDM5B ARID1B

3.92e-03151142418
GeneFamilyDEAH-box helicases

DHX38 DHX30

4.46e-03161142500
GeneFamilyCadherin related

FAT4 CDH23

5.04e-0317114224
GeneFamilySRY-boxes

SOX5 SOX14

6.28e-03191142757
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB1 PLCB3

6.28e-03191142832
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_1_CELL

ZNF536 CT45A6 CT45A1 CT45A10 CT45A2 CT45A7 CT45A9 CT45A8 CT45A3 CT45A5

7.41e-116919010M45681
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

ZNF536 CT45A6 CT45A1 CT45A10 CT45A2 CT45A7 CT45A9 CT45A8 CT45A3 CT45A5

4.57e-0910419010M45682
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

MAOB ETFA NIPSNAP2 MFSD4B PANK1 LECT2 BDH1 SLC2A2 SUGCT PLA2G12B PKHD1 SCP2 AGMAT FKBP5 ALDH7A1 SLC44A3 ALG13

4.10e-0753519017MM3635
CoexpressionFAN_OVARY_CL6_PUTATIVE_EARLY_ATRETIC_FOLLICLE_THECAL_CELL_2

MYADM MAOB PDGFRL MATN2 CCDC80 GDI2 AEBP1 MORF4L2 KLHDC8A SCP2 ALDH7A1

1.30e-0530019011M41708
CoexpressionGSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP

ZNF536 FLT4 PCLO CCDC83 IGF1R CSF1R MYOZ1 PTCH2 DNAH6

1.64e-052001909M4305
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

CNTN4 FRAS1 PCLO IGF1R PLXDC2 SUGCT PKHD1 MAPK10 FKBP5

3.59e-052211909M39222
CoexpressionPASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP

ABCC1 CACNB3 MATN2 RHOBTB3 PIWIL4 PRDM1 IGF1R ANTXR1 TMED9 ALDH7A1

4.99e-0528719010M6510
CoexpressionPASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP

ABCC1 CACNB3 MATN2 RHOBTB3 PIWIL4 PRDM1 IGF1R ANTXR1 TMED9 ALDH7A1

6.63e-0529719010MM1003
CoexpressionNAKAYA_MONOCYTE_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN

ABCC1 UBE3B ADNP2 PEX6 PRDM1 PLCB1

6.82e-05951906M41179
CoexpressionGAO_LARGE_INTESTINE_24W_C1_DCLK1POS_PROGENITOR

SFRP2 PDGFRL MATN2 CCDC80 TNFAIP6 MAPK10

8.59e-05991906M39152
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN

DOCK2 PTTG1 HECTD3 RBBP6 GRK6 UBE3B SNRNP200 ALDH7A1

9.64e-051961908M4973
CoexpressionDELYS_THYROID_CANCER_UP

TNC RHOBTB3 CPD SLC1A5 PRDM1 CSF1R KLHDC8A PLAG1 TNFAIP6 HAS2 TNFSF15 PLXNB1

1.06e-0444519012M3645
CoexpressionGSE14308_TH2_VS_NATURAL_TREG_DN

PTTG1 SLC35B3 DHX30 PITPNM1 SEPSECS PABPC1L CATSPERG TAP2

1.07e-041991908M3369
CoexpressionGSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN

CUL2 PTTG1 ACACA HECTD3 GRK6 ARID1B MORF4L2 NDUFAF7

1.07e-041991908M3569
CoexpressionGSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP

MYADM PSMD9 NEB PRDM1 CLIC5 GFOD1 UBA6 PLEC

1.07e-041991908M5769
CoexpressionGSE4142_PLASMA_CELL_VS_GC_BCELL_UP

MATN2 ADNP2 MATN4 DNAAF9 PTK6 FOXB1 PLEC SNRNP200

1.11e-042001908M6390
CoexpressionGSE17721_4_VS_24H_CPG_BMDC_DN

ADNP2 COPG2 GDI2 SLC1A5 BDH1 NDUFAF7 MORF4L1 ANTXR1

1.11e-042001908M4131
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SFRP2 TNC PCDH11Y VEPH1 PLXDC2 AEBP1 ANTXR1 TNFAIP6 MAPK10 FKBP5

1.04e-0920018911a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC1 HECTD3 PSMD9 SEC14L3 CLIC5 PIK3C2B NDUFAF7 KLHDC8A GGACT TNFSF15

4.23e-0917518910711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 ACSS3

1.14e-08194189106e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 FRAS1 PCLO SLC2A2 SLC3A1 SUGCT PKHD1 MAPK10 SCIN

8.90e-0818218999d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 ACSS3

1.23e-071891899a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 ACSS3

1.34e-071911899b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SOX5 CNTN4 ACADL VEPH1 ADGRV1 SLC9C1 CLIC5 PKHD1 SLC44A3

1.34e-071911899d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ACACA ACADL PCLO VEPH1 ADGRV1 PANK1 MAPK10 ACSS3

1.40e-071921899cc9911e182a289779a2612bc213daae5607689e7
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DNAAF9 ARID1B IGF1R PLXDC2 SUGCT PKHD1 MAPK10 FKBP5

1.40e-071921899e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 ACSS3

1.40e-071921899dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

CNTN4 ABCC1 ARID1B PLXDC2 PLCB1 ANTXR1 HAS2 MAPK10 FKBP5

1.67e-071961899e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SFRP2 CCDC80 PLXDC2 AEBP1 ANTXR1 MAPK10 FKBP5 ACSS3

1.99e-072001899c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP2 PDGFRL TNC RHOBTB3 CCDC80 AEBP1 ANTXR1 TNFAIP6 HAS2

1.99e-07200189954806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX5 DNHD1 THEMIS FOXB1 CLIC5 SUGCT ANTXR1 PLAG1

4.75e-071621898fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX5 DNHD1 THEMIS FOXB1 CLIC5 SUGCT ANTXR1 PLAG1

4.75e-07162189845be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PCLO VEPH1 ADGRV1 PKHD1L1 AEBP1 PKHD1 DNAH6

6.55e-07169189812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 FRAS1 ACADL VEPH1 SLC9C1 CLIC5 TNFSF15 SLC44A3

7.82e-071731898b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 ZNF536 PDGFRL TNC MATN2 SLC9C1 PLXDC2 ANTXR1

1.01e-06179189802c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 PDGFRL TNC MATN2 TNN TNFAIP6 HAS2 CATSPERG

1.10e-0618118980b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 ACACA ACADL VEPH1 ADGRV1 SLC9C1 MAPK10 ACSS3

1.19e-0618318986847c1252d6bb105524f812658112517fd351eab
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 PCLO CNKSR2 ADGRV1 NEB PKHD1L1 PKHD1

1.24e-0618418982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 PCLO CNKSR2 ADGRV1 NEB PKHD1L1 PKHD1

1.24e-0618418982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 PCLO CNKSR2 ADGRV1 NEB PKHD1L1 PKHD1

1.24e-061841898ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 HAS2 ACSS3

1.52e-061891898e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 ACSS3

1.52e-0618918982a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CNTN4 FAT4 TNC AEBP1 PLCB1 ANTXR1 FKBP5

1.52e-061891898c734e5693808a0333139e87bd5be2597a9252afe
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM PDGFRL ACLY MATN2 GDI2 UBA1 CSF1R FKBP5

1.58e-0619018981d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 ACSS3

1.58e-061901898841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ACADL PCLO VEPH1 CLDN3 ADGRV1 PKHD1 SLC44A3

1.58e-061901898c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 HAS2 ACSS3

1.58e-061901898d60395739458d7f47a3350ade751fe3819500320
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 VEPH1 ADGRV1 PKHD1 MAPK10 SCIN TNFSF15 ACSS3

1.64e-06191189834cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 CNTN4 ACACA ACADL VEPH1 ADGRV1 MAPK10 ACSS3

1.64e-061911898e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 PDGFRL TNC CCDC80 PLXDC2 AEBP1 KLHDC8A ANTXR1

1.71e-061921898b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 ACSS3

1.71e-0619218983d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 ANTXR1 ACSS3

1.71e-0619218986f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 MAOB TNC CCDC80 PLXDC2 AEBP1 HAS2 ACSS3

1.71e-061921898f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CNTN4 TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2

1.71e-061921898162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CNTN4 TNC CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2

1.71e-0619218984e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 MAP1B TNC MATN2 CCDC80 AEBP1 ANTXR1 TNFAIP6

1.78e-061931898dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX5 ZNF536 CT45A6 CT45A1 CT45A10 CT45A2 CT45A9 CT45A5

1.78e-0619318982f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 FAT4 ZNF536 MAP1B PLXDC2 AEBP1 SUGCT ANTXR1

1.78e-061931898e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

SOX5 FRAS1 RHOBTB3 VEPH1 PKHD1 MAP3K15 MAPK10 SCIN

1.78e-061931898738689d009e4b118d7ce3171a207294b95cbe78b
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PDGFRL MATN2 CCDC80 SLC1A5 AEBP1 ANTXR1 SCIN

1.78e-061931898d08919db9601941569b9a143dad4d8e6f56a4389
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PDGFRL MATN2 CCDC80 SLC1A5 PLXDC2 AEBP1 ANTXR1

1.78e-061931898ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 MAP1B TNC MATN2 CCDC80 AEBP1 ANTXR1 TNFAIP6

1.78e-061931898e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PDGFRL MATN2 CCDC80 SLC1A5 PLXDC2 AEBP1 ANTXR1

1.78e-061931898735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PDGFRL MATN2 CCDC80 SLC1A5 AEBP1 ANTXR1 SCIN

1.78e-0619318980ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCellLA|World / Chamber and Cluster_Paper

SOX5 CNTN4 MAP1B CCDC80 PLXDC2 PLCB1 ANTXR1 MAPK10

1.78e-061931898d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 PCLO SLC3A1 PKHD1 MAPK10 SCIN PLXNB1 SLC44A3

1.85e-0619418985eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 MAP1B MATN2 CCDC80 CNKSR2 AEBP1 PTCH2 ANTXR1

1.85e-061941898c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellfacs-Heart-LA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 PDGFRL MATN2 CCDC80 SLC1A5 AEBP1 ANTXR1 SCIN

1.85e-06194189834b54bea013c8c724fadae357e29953c291bfce1
ToppCellfacs-Heart-LA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 PDGFRL MATN2 CCDC80 SLC1A5 AEBP1 ANTXR1 SCIN

1.85e-0619418989a5dd7ae6de72a000cf9a0d42f6b0884fa43f345
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRL TNC CCDC80 PLXDC2 AEBP1 ANTXR1 TNFAIP6 SCIN

1.92e-061951898d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYADM SFRP2 MAP1B PDGFRL TNC CCDC80 AEBP1 TNFAIP6

1.92e-06195189847762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 MYADM SFRP2 RHOBTB3 CCDC80 PLXDC2 AEBP1 ANTXR1

1.92e-061951898223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 ACACA ACADL VEPH1 ADGRV1 SLC9C1 CLIC5 MAPK10

1.92e-0619518989406866f99555198a9be311fbd65751b70f35446
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

FAT4 SFRP2 PDGFRL MATN2 CCDC80 MATN4 AEBP1 TNFAIP6

1.99e-0619618987e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 ACACA VEPH1 ADGRV1 ARID1B IGF1R MAPK10 COG5

1.99e-061961898ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

FAT4 SFRP2 PDGFRL MATN2 CCDC80 MATN4 AEBP1 TNFAIP6

1.99e-06196189854aefcebf13704f51de84379e2e22ec0734b9461
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 SFRP2 PDGFRL TNC CCDC80 SYT2 CLIC5 AEBP1

1.99e-061961898545d2e4469924d333e3f655f559c899fa1260196
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FAT4 MAOB TNC CDH23 PLXDC2 SUGCT ANTXR1 MAPK10

2.07e-061971898f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 SFRP2 PDGFRL TNC CCDC80 SYT2 CLIC5 AEBP1

2.23e-061991898b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNC RHOBTB3 CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 MAPK10

2.23e-061991898a272c54baf8de59c0f259e6498d144a0de8d8924
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 SFRP2 PDGFRL TNC CCDC80 SYT2 CLIC5 AEBP1

2.23e-061991898c972d3036151403f26fa9d6271520639c281ab84
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FAT4 TNC MATN2 RHOBTB3 PLXDC2 ANTXR1 HAS2 MAPK10

2.23e-0619918983a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TNC RHOBTB3 CCDC80 PLXDC2 AEBP1 ANTXR1 HAS2 MAPK10

2.23e-061991898d9d7f36b4b5592b7855448730044c90997b55499
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP2 PDGFRL TNC CCDC80 AEBP1 ANTXR1 TNFAIP6 HAS2

2.32e-0620018986e3d1ae0ef84d3075afa40129a41169996462672
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SFRP2 MAP1B AEBP1 TNN ANTXR1 TNFAIP6 HAS2

2.32e-0620018988ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP2 MAP1B TNC CCDC80 AEBP1 ANTXR1 TNFAIP6 HAS2

2.32e-0620018982e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell356C-Fibroblasts|356C / Donor, Lineage, Cell class and subclass (all cells)

SFRP2 MAP1B PDGFRL MATN2 CCDC80 AEBP1 ANTXR1 HAS2

2.32e-0620018989c95329f0b26ff378de803030d4c28517b3adc85
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SFRP2 MAP1B PDGFRL TNC AEBP1 SUGCT TNN ANTXR1

2.32e-0620018989bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 FRAS1 USP29 ADGRV1 SLC9C1 PKHD1 HEPHL1

2.92e-06145189796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH3 RHOBTB3 DHX38 CEP192 SYT2 SLC1A5 FAM111A

4.00e-0615218970652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZNF536 CT45A6 CT45A1 CT45A10 CT45A2 CT45A9 CT45A5

4.95e-061571897b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

PITPNM2 DNAH3 SFRP2 MAOB SUGCT KLHDC8A PABPC1L

5.16e-061581897ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 CNTN4 FRAS1 ADGRV1 PKHD1L1 PKHD1 HEPHL1

5.60e-061601897c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 CNTN4 FRAS1 ADGRV1 PKHD1L1 PKHD1 HEPHL1

5.60e-06160189725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 USP29 ADGRV1 NEB PKHD1L1 PKHD1 HEPHL1

6.08e-061621897bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FRAS1 SFRP2 CCDC80 PKHD1L1 AEBP1 AGMAT SCIN

7.13e-061661897545f6c91102568791443717e522f89cb3bd1a070
ToppCellControl|World / group, cell type (main and fine annotations)

SOX5 CNTN4 ACADL VEPH1 ADGRV1 SLC9C1 MAPK10

7.71e-061681897a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FAT4 MAP1B TNC CCDC80 AEBP1 ANTXR1

8.66e-061711897972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FAT4 MAP1B TNC CCDC80 AEBP1 ANTXR1

8.66e-0617118972a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CNTN4 FRAS1 PCLO SLC3A1 SUGCT PKHD1 MAPK10

1.04e-05176189736f77d878a53b30465b0dea8333a3865dba75613
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FRAS1 MATN4 CLDN3 SLC1A5 SEC14L3 IGF1R CLIC5

1.04e-051761897f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRL TNC CCDC80 DNAH17 PLCB1 TNFAIP6 TNFSF15

1.08e-051771897bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

SOX5 ACACA ACADL VEPH1 ADGRV1 MAPK10 ACSS3

1.21e-051801897198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 PCLO SLC2A2 SLC3A1 SUGCT PLA2G12B PKHD1

1.25e-0518118976980ea624151da32b7f537f263e40fcb87a02e81
ToppCellBasal|World / shred by cell class for mouse tongue

MYADM MAP1B MATN2 COQ8A MORF4L1 ANTXR1 PLEC

1.35e-051831897c6729a207526ff4aa48176207b9353176f631fea
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B PDGFRL MATN2 CCDC80 CNKSR2 PLXDC2 AEBP1

1.35e-051831897a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCelldroplet-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B PDGFRL MATN2 CCDC80 CNKSR2 PLXDC2 AEBP1

1.35e-051831897ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 PDGFRL TNC MATN2 RHOBTB3 PLXDC2 ANTXR1

1.35e-05183189712daaea821e49bc94a01e2496331e92a80d27339
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ACADL RHOBTB3 PCLO VEPH1 CLIC5 MAPK10 SLC44A3

1.35e-0518318976821dca076318115d360ff426eb1218cfe104063
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

MYADM PDGFRL MATN2 CCDC80 MATN4 AEBP1 ANTXR1

1.39e-051841897684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 ZNF536 PDGFRL TNC MATN2 PLCB1 ANTXR1

1.44e-0518518973b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellfacs-Heart-LA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB MATN2 CCDC80 SLC1A5 AEBP1 TNFAIP6 SCIN

1.49e-051861897ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB MATN2 CCDC80 SLC1A5 AEBP1 TNFAIP6 SCIN

1.55e-0518718971669df899b1759c338ffce196fe009840123cfcd
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 CCDC80 PKHD1L1 PLXDC2 AEBP1 ANTXR1 ACSS3

1.55e-0518718974e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 CCDC80 PKHD1L1 PLXDC2 AEBP1 ANTXR1 ACSS3

1.55e-051871897d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 CCDC80 PKHD1L1 PLXDC2 AEBP1 ANTXR1 ACSS3

1.55e-051871897827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB MATN2 CCDC80 SLC1A5 AEBP1 TNFAIP6 SCIN

1.55e-051871897f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
DiseaseStevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide

SLC35B3 SEC14L3 TAP2

3.49e-05111793EFO_0004276, EFO_0004775, EFO_0020996
DiseaseSquamous cell carcinoma of lung

ANKK1 IGF1R CSF1R MAP3K15

4.12e-05321794C0149782
DiseaseHEMANGIOMA, CAPILLARY INFANTILE

FLT4 ANTXR1

1.09e-0431792602089
DiseaseHEMANGIOMA, CAPILLARY INFANTILE

FLT4 ANTXR1

1.09e-0431792C1865871
Diseaseelectrocardiography, P wave duration

SFRP2 PKHD1

1.09e-0431792EFO_0004327, EFO_0005094
Diseasegastrinoma (is_marker_for)

SLC2A2 IGF1R

1.09e-0431792DOID:5577 (is_marker_for)
DiseaseCapillary infantile hemangioma

FLT4 ANTXR1

1.09e-0431792cv:C1865871
DiseasePontoneocerebellar hypoplasia

PCLO EXOSC3 SEPSECS

1.16e-04161793cv:C1261175
DiseaseMacrostomia

FRAS1 PTCH2

2.18e-0441792C0024433
Diseasepantothenate kinase-associated neurodegeneration (implicated_via_orthology)

PANK3 PANK1

2.18e-0441792DOID:3981 (implicated_via_orthology)
Diseaselung adenocarcinoma (is_implicated_in)

MSH2 LECT2 PRDM1 UBR5

2.24e-04491794DOID:3910 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

IPO5 FLT4 RBBP6 MSH2 GDI2 ARID1B CSF1R PIP4K2C

2.45e-042681798DOID:162 (implicated_via_orthology)
Diseasetriacylglycerol 54:8 measurement

CNTN4 SLC35B3 PLCB1

3.56e-04231793EFO_0010426
Diseasehyperthyroidism (biomarker_via_orthology)

BDH1 IGF1R UCP3

6.43e-04281793DOID:7998 (biomarker_via_orthology)
Diseaseglutamate measurement

RHOBTB3 CDH23 COG5

7.14e-04291793EFO_0010487
DiseaseMental Retardation, X-Linked 1

CNKSR2 CLCN4 ALG13

9.57e-04321793C2931498
Diseasecarnitine measurement

ABCC1 ACADL ETFA PLCB1

1.20e-03761794EFO_0010469
DiseaseInflammatory Bowel Diseases

CUL2 SFRP2 TNFSF15

1.25e-03351793C0021390
DiseaseColorectal Carcinoma

CNTN4 ABCC1 RELCH DNAH3 SFRP2 ACACA MAP1B PDGFRL CNKSR2 MSH2 PKHD1 SNRNP200

1.26e-0370217912C0009402
Diseaseuric acid measurement

SOX5 CNTN4 DNAH3 FAT4 FRAS1 FLT4 ADGRV1 SLC2A2 IGF1R AGMAT MAPK10

1.31e-0361017911EFO_0004761
Diseaseglycine measurement

PDGFRL GRK6 NIPSNAP2 ADGRV1 SLC36A3

1.52e-031371795EFO_0009767
Diseaseneuroblastoma (is_implicated_in)

ARID1B IGF1R

1.59e-03101792DOID:769 (is_implicated_in)
Diseaselung cancer (is_marker_for)

TNC PRDM1 CSF1R

1.71e-03391793DOID:1324 (is_marker_for)
DiseaseLeukoencephalopathy

CSF1R SCP2

1.94e-03111792C0270612
Diseaseobesity (implicated_via_orthology)

FAT4 GNL3L PLCB1 SCP2 PLCB3 PLXNB1

2.06e-032151796DOID:9970 (implicated_via_orthology)
Diseasevisual epilepsy (biomarker_via_orthology)

MAP1B MSH2 RRM1 BRD1

2.23e-03901794DOID:11832 (biomarker_via_orthology)
DiseaseAbruptio Placentae

DOCK2 PDGFRL

2.32e-03121792EFO_1001754
Diseaseimmunoglobulin isotype switching measurement

UBR4 SEC14L3 TAP2

2.42e-03441793EFO_0010128
DiseaseMalignant neoplasm of stomach

FAT4 MSH2 CLDN3 DDB1 UBR5 PUS1 ALDH7A1

2.46e-033001797C0024623
DiseaseNeurodevelopmental Disorders

DHX30 ARID1B PLXNB1 ALG13

2.51e-03931794C1535926
Diseaselymphocyte percentage of leukocytes

CDH23 GTF2IRD2B CSF1R COQ8A UBR5 GFOD1 MORF4L2 GTF2IRD2 PLCB1 PLCB3 FKBP5

2.57e-0366517911EFO_0007993
Diseaserheumatoid arthritis, smoking status measurement, ACPA-positive rheumatoid arthritis

SEC14L3 TAP2

2.73e-03131792EFO_0000685, EFO_0006527, EFO_0009459
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 CLIC5

2.73e-03131792C1846647
DiseaseSjogren's Syndrome

PTTG1 PRDM1

2.73e-03131792C1527336
DiseaseCongenital pontocerebellar hypoplasia

EXOSC3 SEPSECS

2.73e-03131792C0266468
DiseaseSicca Syndrome

PTTG1 PRDM1

2.73e-03131792C0086981
DiseaseParkinson's disease (implicated_via_orthology)

TPPP2 ARPC3 IGF1R PTCH2 MAPK10

2.76e-031571795DOID:14330 (implicated_via_orthology)
DiseaseAdenocarcinoma of large intestine

PDGFRL MSH2 UBR5 MAP3K15

2.82e-03961794C1319315
Diseasemyocardial infarction (biomarker_via_orthology)

SFRP2 TNC IGF1R PLCB1 PLCB3

2.99e-031601795DOID:5844 (biomarker_via_orthology)
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

CSF1R SCP2

3.17e-03141792C1858991
Diseaseprostate carcinoma

DOCK2 TNC NVL GDI2 IGF1R FAM111A SUGCT PIK3C2B PKHD1 PLAG1 TNFAIP6 CATSPERG DMAC1

3.20e-0389117913EFO_0001663
DiseaseDisease Exacerbation

ABCC1 RRM1 DDB1 PUS1 ALDH7A1

3.41e-031651795C0235874
Diseasehematocrit

SOX5 ACACA DHX38 PEX6 DNAAF9 ADGRV1 PANK1 ARID1B SUGCT PKHD1 PLCB1 AGMAT PLCB3 ALDH7A1

3.58e-03101117914EFO_0004348
DiseaseLiver carcinoma

PTTG1 ACACA PDGFRL ACLY ETFA RRM1 SLC2A2 ARID1B IGF1R

3.95e-035071799C2239176
Diseasemonoclonal gammopathy

CNTN4 TNC CNKSR2

4.12e-03531793EFO_0000203
Diseaseresponse to thioamide, Drug-induced agranulocytosis

SEC14L3 TAP2

4.15e-03161792EFO_0007633, HP_0012235
Diseaseamyloid-beta measurement, Alzheimer's disease biomarker measurement

RELCH PLXDC2

4.15e-03161792EFO_0005194, EFO_0006514
Diseasesuccinylcarnitine measurement

ABCC1 ZNF536

4.15e-03161792EFO_0020020
Diseasedepressive symptom measurement

SOX5 ANKK1 PCLO UBE3B CNKSR2 SEC14L3 PKHD1 TAP2

4.64e-034261798EFO_0007006
Diseaseglutarylcarnitine (C5-DC) measurement

ABCC1 ETFA

4.69e-03171792EFO_0800030
Diseasehepatocellular carcinoma (is_implicated_in)

PDGFRL LECT2 PRDM1 IGF1R CSF1R

5.04e-031811795DOID:684 (is_implicated_in)
Diseasefactor VIII measurement, coronary artery disease

UBE3B SEC14L3 MORF4L1 TAP2

5.05e-031131794EFO_0001645, EFO_0004630
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX5 IGF1R PLCB1

5.05e-03571793DOID:10652 (implicated_via_orthology)
Diseaseheel bone mineral density, urate measurement

CNTN4 THEMIS GDI2 PUS1 BRD1

5.16e-031821795EFO_0004531, EFO_0009270
Diseaseserum metabolite measurement

CNTN4 ABCC1 ACADL GRK6 DHX38 VEPH1 PSMD9 SUCLA2 MFSD4B CSF1R CLIC5 DNAH17 AGMAT

5.22e-0394517913EFO_0005653
DiseaseAdrenocortical carcinoma

RRM1 IGF1R

5.25e-03181792C0206686
DiseaseTourette syndrome, schizophrenia

PITPNM2 ZNF536

5.25e-03181792EFO_0004895, MONDO_0005090
Diseaseautoimmune thyroid disease, type 1 diabetes mellitus

SEC14L3 TAP2

5.25e-03181792EFO_0006812, MONDO_0005147
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PCLO CDH23

5.85e-03191792EFO_0007044, EFO_0020106

Protein segments in the cluster

PeptideGeneStartEntry
FVENYVPGKLSAMGL

SUGCT

136

Q9HAC7
PIYLGAMFSLQEGDK

TNFSF15

211

O95150
ILGGIPNEKYVLMTD

CATSPERG

251

Q6ZRH7
RPLNIYGDVEMKNGV

BRD1

396

O95696
YAPVGIMFLVAGKIV

SLC1A5

276

Q15758
GIVVMADPKGKAYRV

DMAC1

101

Q96GE9
QKMPGGYVPEIVISE

ALG13

566

Q9NP73
LEELQKVLPGGDTYM

ANTXR1

106

Q9H6X2
VLVGPSLKGYEVTDM

CACNB3

181

P54284
RVQPIYGGTNEIMKE

ACADL

406

P28330
MYPLGVKVSVVEPGN

BDH1

226

Q02338
MGKILVEGVGEVQEY

ALDH7A1

136

P49419
GLKIYAMEISDNPGE

AEBP1

596

Q8IUX7
IYGVCKQPLGIVMEF

ANKK1

86

Q8NFD2
KAVDPDEGVNGMVLY

FAT4

916

Q6V0I7
AIKGPELMNKYVGES

SPATA5

691

Q8NB90
IEFYLDGNAMPRGIK

ADGRV1

1436

Q8WXG9
NDGVMGEYEPKIEVQ

CNTN4

216

Q8IWV2
YEKIFEMLEGVQGPT

CT45A5

141

P0DMU8
AEEVGYPVMIKASEG

ACACA

301

Q13085
GILMEYEVGDPSQKA

ARID1B

1766

Q8NFD5
ELTGGLEYIVPLMAA

CLCN4

541

P51793
KLEDMRGGPIKNYVT

DNHD1

731

Q96M86
EEELVKGVLMAGLYP

DHX30

1011

Q7L2E3
YMLILEAIDNGPVGK

CDH23

1066

Q9H251
MNPEIYLFVKAGIDG

CLIC5

171

Q9NZA1
YEKIFEMLEGVQGPT

CT45A7

141

P0DMV0
GIYAMGFNRPSKIQE

DDX25

111

Q9UHL0
YFGLRTEEMGEQPKT

ADNP2

186

Q6IQ32
PEYFSMLLVGKDGNV

CCDC80

861

Q76M96
DYVNLGPLGVKLMSV

CCDC83

361

Q8IWF9
GIFEPFGKIDNIVLM

RBM23

281

Q86U06
EGGYPALTEVMNKLR

NIPSNAP2

131

O75323
MELLGEYVGQEGKPQ

GON7

1

Q9BXV9
VKGPELLNMYVGESE

NVL

646

O15381
AIEPDGNGLMIVSYK

NUDCD1

236

Q96RS6
VVAGIKEYFNVMLGT

MORF4L1

256

Q9UBU8
KYLGMTLVEQPKGEE

LDLRAP1

51

Q5SW96
TKPEGNYAAIMGFIL

MAOB

331

P27338
IKSLGIIMGYIDDPD

RELCH

661

Q9P260
GNGEETPMIGDKVYV

FKBP5

41

Q13451
GGKYMQAVIQYGKIV

FKBP5

281

Q13451
TEMNGRIVGSKPLYV

PABPC4

351

Q13310
GGTYMLNKPIEEIIV

GDI2

246

P50395
EFAIVSGKLEPGMTY

PNLIPRP3

386

Q17RR3
MPGVDGFTLKVDALY

FRAS1

3796

Q86XX4
GITMYAVGVGKAIEE

MATN2

786

O00339
EGIVMYAVGVGKAVE

MATN4

516

O95460
GVGKLEMYVLNPVKS

MAP1B

416

P46821
LTYEGSLIDDQGMPK

MAGEC3

531

Q8TD91
APEVILGMGYKENVD

MAPK10

231

P53779
YEKIFEMLEGVQGPT

CT45A10

141

P0DMU9
NFMGLIEVVTGYVKI

IGF1R

376

P08069
ENPNGLILMYEIKYG

IGF1R

856

P08069
FVKVYLLPGRGQVMV

PCLO

4731

Q9Y6V0
DSVGEPLYMLFRGIK

PLXNB1

1701

O43157
LSVKGPELINMYVGQ

PEX6

766

Q13608
YEKIFEMLEGVQGPT

CT45A3

141

Q8NHU0
SKPVYATIGVGAVNM

SLC2A2

336

P11168
LKEIGERFPYLTGQM

VEPH1

276

Q14D04
VYAPFTGMIVGQEKP

LECT2

66

O14960
EVVAGIKEYFNVMLG

MORF4L2

181

Q15014
TGYMATVPGLLKVLE

MYADM

166

Q96S97
MALVFVYGTLKRGQP

GGACT

1

Q9BVM4
GVPGYAAEQLENVMK

KDM5B

521

Q9UGL1
YFLGLKVPESMDLGI

PLA2G12B

91

Q9BX93
IDYPKALQILMEGGT

POMGNT2

51

Q8NAT1
TEMNGRIVGTKPLYV

PABPC1L

351

Q4VXU2
LGVGVYPIKMVVRGD

PITPNM2

1076

Q9BZ72
GKEFQQYLPVVMGPL

IPO5

616

O00410
SKYPLMEEIGFLVLG

IPMK

166

Q8NFU5
EMAIPAVIGILQGKY

MFSD4B

366

Q5TF39
TALMEEKGYQVPVLG

RBBP6

456

Q7Z6E9
AIENIIAREYKMPGG

FOXB1

171

Q99853
VGDPVYIITELMAKG

PTK6

256

Q13882
EMLVYDGIPKGDLQQ

PIK3C2B

1571

O00750
MDIGGTLVKLSYFEP

PANK3

16

Q9H999
RKVGIYVEVDMFGLP

PLCB3

741

Q01970
PGVVRMVIGSKFDQY

CPLANE2

166

Q9BU20
EGKEFAPVYPIMVQL

COG5

816

Q9UP83
YEKIFEMLEGVQGPT

CT45A1

141

Q5HYN5
LKVMVEAYPGLQGFN

CSF1R

321

P07333
YEKIFEMLEGVQGPT

CT45A9

141

P0DMV2
LNPKSITMGELYGEV

DNAH6

1791

Q9C0G6
ETVFLLETMLGGPQY

FASTKD5

561

Q7L8L6
ESGYAGKISQMPVIL

GMPS

601

P49915
VGAGDKPMNEYRSVV

DOCK2

466

Q92608
AQGIGDPKYVPVTDM

DNAH17

2736

Q9UFH2
MGKLYIEAPTFDLQG

DNAH3

3496

Q8TD57
VMENNPEDGAYIKGL

DNAH3

4006

Q8TD57
GEKEMYTLGITNFPI

ARPC3

91

O15145
LMLESGYIPQGTEAK

FBXO7

206

Q9Y3I1
NYMVGLQVPSLGEKD

CFAP70

191

Q5T0N1
TEGIKEYINLGMPLS

FAM111A

131

Q96PZ2
YEKIFEMLEGVQGPT

CT45A2

141

Q5DJT8
YPGIKVVMVIDGNSE

HAS2

111

Q92819
TGEVKMNYLGKPYVA

CUL2

561

Q13617
GYMPLTVTNVVVKEG

CPD

436

O75976
GGREVAMKIQYPGVA

COQ8A

351

Q8NI60
GKLNAGSVYPLMVQI

DNAAF9

961

Q5TEA3
YIFNGLTVSVPGMEK

COPG2

546

Q9UBF2
NFVKDTYSGLMGPLI

HEPHL1

891

Q6MZM0
YMVTVNGLVPGKESK

CEP192

1896

Q8TEP8
YEKIFEMLEGVQGPT

CT45A8

141

P0DMV1
PGAEKIAGLSQIYKM

FOXN2

16

P32314
QIYKMGSLPEAVDAA

FOXN2

26

P32314
DFILSKGYEMPGIIQ

FAM47A

741

Q5JRC9
GVGTNQLPLKVVEMY

KLHDC8A

86

Q8IYD2
RLGVEMGKVQVYQEP

PRPSAP2

41

O60256
QVMEGGQVEYKPLSG

SLC44A3

361

Q8N4M1
IQAAGYPDKVVIGMD

ENO3

231

P13929
QTGKVIEQMGKFYPE

DDX19A

176

Q9NUU7
VGTVGYMAPEVVKNE

GRK6

346

P43250
GVVFKAPGYLEISSM

GTF2IRD2

376

Q86UP8
GVVFKAPGYLEISSM

GTF2IRD2B

376

Q6EKJ0
GGEIPKSMYVRDQVK

SEC14L3

261

Q9UDX4
VGKLYPLEIVFGMNG

EXOSC3

221

Q9NQT5
EVFKTQGVIKYMGPA

MSH2

56

P43246
YEKIFEMLEGVQGPT

CT45A6

141

P0DMU7
LGKDPNTYFIVGTAM

DDB1

821

Q16531
MATLIYVDKENGEPG

PTTG1

1

O95997
TYVMKVKVEDGGFPQ

PCDH11Y

246

Q9BZA8
GAPQKEVYFMGLIDI

PIP4K2C

361

Q8TBX8
GNYMEAKSVLIPVYG

RHOBTB3

451

O94955
MDIGGTLVKLVYFEP

PANK1

241

Q8TE04
YLPQVDVIIVMSGGK

ABCC1

831

P33527
YIKIFMEQVPGGSLS

MAP3K15

721

Q6ZN16
YDVLESQKGIGMNEP

PSMD9

41

O00233
KVPYQELGGKTLVMA

SYT2

211

Q8N9I0
PYLVMGQKQGGELVI

SFRP2

256

Q96HF1
QMAYLGSLPVIGEKE

TEX14

226

Q8IWB6
GDEPKGIYIIISGMV

SLC9C1

901

Q4G0N8
MKQLIEEGYVGEPLV

GFOD1

131

Q9NXC2
LERNAGSPVYMKGVT

NDUFAF7

176

Q7L592
FTVQMDDYLGGKPVQ

SCIN

81

Q9Y6U3
KMVGLVVAIVKGYAP

PUS1

296

Q9Y606
MQVGQTGKIVAPELY

ETFA

261

P13804
GAVPGITKFMQEVYL

GNL3L

281

Q9NVN8
YKSGVPLIENGMIER

PTCH2

161

Q9Y6C5
GSMGFNVDYPKIIKV

PIWIL4

511

Q7Z3Z4
MDGRIIFGYKEIPVL

PLXDC2

251

Q6UX71
IPGKTYMIIAFLTVG

SLC35B3

141

Q9H1N7
IPVMLGGVFIQGKRY

SLC35B3

181

Q9H1N7
GVQPYAGMPKEVLFQ

SLC3A1

61

Q07837
VKVVGLYGFMLSISP

TAP2

276

Q03519
EVRQQMGGKPIYISF

AGMAT

261

Q9BSE5
MGGKPIYISFDIDAL

AGMAT

266

Q9BSE5
EEVIGVMSKEYIPKG

PRDM1

96

O75626
MATLIYVDKEIGEPG

PTTG2

1

Q9NZH5
KGLYVMGTLDFPVDR

PKHD1

2781

P08F94
IKNILITYIGMVFGG

SLC35D1

291

Q9NTN3
IPANGTDIVYDMKRG

PDGFRL

216

Q15198
GAVVVTLYKMGFPEA

SCP2

396

P22307
MELLQEAGVSVPKGY

SUCLA2

61

Q9P2R7
IFTFEGVGMVLPLKN

SLC36A3

261

Q495N2
KMIVVLGEIGGTEEY

ACLY

711

P53396
GKSVPGYNVMILDDN

ACSS3

476

Q9H6R3
VPEAQKREMGAGLYV

CLDN3

151

O15551
IQLANIKPSEGLGMY

CNKSR2

216

Q8WXI2
LENIYGLMEGKDPAT

TPPP2

91

P59282
PLKGEIESYLMELQG

PLAG1

351

Q6DJT9
YQPATPGLGMFVEVK

TMED9

76

Q9BVK6
GEKVDVYIMTQPLSG

PITPNM1

951

O00562
GTLILKPVYEIQGVM

THEMIS

221

Q8N1K5
ALEMIKVTGGYPFEA

UBA6

906

A0AVT1
KEKYGIEPTMVVQGV

UBA6

976

A0AVT1
GNIVVIMISYPKGRE

RNF149

156

Q8NC42
IKMVAQEGPTAFYKG

UCP3

261

P55916
TAGGFQIKYVAMDPV

TNFAIP6

236

P98066
IVGYGDFQMKQIDAP

TSR1

291

Q2NL82
TYQFPDGTVKEMQLG

TNN

1006

Q9UQP3
PAQITMKVIQGLYSG

RRM1

36

P23921
GPLMVIVEFCKYGNL

FLT4

921

P35916
PGVEYLVSIIAMKGF

TNC

1771

P24821
DISLPVMYEDGGKLI

USP29

656

Q9HBJ7
LAELGPMFYSVKQAG

DHX38

1141

Q92620
VPLKTGEGEEYMLAL

POLR3G

46

O15318
SQVGIGDYRIPKAML

PKHD1L1

3711

Q86WI1
VYQAMKKGIIRPGTA

PLEC

4086

Q15149
GNQPMEIKVLGPYTF

UBA1

261

P22314
KKVGTYVEVDMFGLP

PLCB1

691

Q9NQ66
VQLMKYGADPSLIDG

ZDHHC17

141

Q8IUH5
YVLVGADGSKQKMPA

ZNF536

566

O15090
SEGIDEMVGIIYKPK

SNRNP200

91

O75643
MLGKAVYEGIVVDVP

UBE3B

781

Q7Z3V4
SLDKNFMVPVGGAII

SEPSECS

281

Q9HD40
MPVIQSTYGVKGEEP

SOX5

706

P35711
LQGPEVGYFSQMKII

ZNF529

131

Q6P280
MYVANTKPGGFTIEI

UBR4

2326

Q5T4S7
PAGVTMIDAVKIYGK

UBR4

2411

Q5T4S7
RGTIPDMIADSGKYI

NAE1

326

Q13564
GDIVALKLGIPFMYS

UGT2A1

156

P0DTE4
VYVIGSFVDKSMQPG

TRMT10C

306

Q7L0Y3
VAYILFPGMTKTGID

SOX14

216

O95416
ILRDGNGTIYPMAKD

UBR5

811

O95071
TDDNFMPKRVVVYGG

HECTD3

301

Q5T447
MPKRVVVYGGEGDNL

HECTD3

306

Q5T447
PGFKAQNGIAIMVYT

ART5

86

Q96L15
PQQKMELGIDLLAYG

MYOZ1

196

Q9NP98
VLYKENMGKGTPLAV

NEB

6276

P20929