Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2D KMT2B KMT2A	3.68e-06	8	82	3	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2D KMT2B KMT2A	7.85e-06	10	82	3	GO:0140999
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	3.16e-05	44	82	4	GO:0140938
GeneOntologyMolecularFunction	histone modifying activity	RIOX2 JARID2 KMT2D KMT2B BRPF1 KMT2A KDM5D	4.36e-05	229	82	7	GO:0140993
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2D KMT2B KMT2A	7.24e-05	20	82	3	GO:0042800
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	1.76e-04	68	82	4	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	1.86e-04	69	82	4	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	2.08e-04	71	82	4	GO:0042054
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD7 BRD9 KMT2A	2.50e-04	30	82	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD7 BRD9 KMT2A	2.76e-04	31	82	3	GO:0140033
GeneOntologyMolecularFunction	histone demethylase activity	RIOX2 JARID2 KDM5D	2.76e-04	31	82	3	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	RIOX2 JARID2 KDM5D	3.04e-04	32	82	3	GO:0140457
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	RIOX2 KDM5D	4.59e-04	8	82	2	GO:0032453
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	JARID2 KMT2D KMT2B KMT2A DNMT1	7.15e-04	172	82	5	GO:0008757
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2B KMT2A	7.34e-04	10	82	2	GO:0045322
GeneOntologyMolecularFunction	demethylase activity	RIOX2 JARID2 KDM5D	7.83e-04	44	82	3	GO:0032451
GeneOntologyMolecularFunction	protein methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	8.58e-04	103	82	4	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	JARID2 KMT2D KMT2B KMT2A	9.22e-04	105	82	4	GO:0008170
GeneOntologyMolecularFunction	methyltransferase activity	JARID2 KMT2D KMT2B KMT2A DNMT1	1.85e-03	213	82	5	GO:0008168
GeneOntologyMolecularFunction	regulatory RNA binding	TUT7 PIWIL2 MBD2	2.12e-03	62	82	3	GO:0061980
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	JARID2 KMT2D KMT2B KMT2A DNMT1	2.30e-03	224	82	5	GO:0016741
GeneOntologyBiologicalProcess	chromatin organization	RIOX2 JARID2 KMT2D SLF1 KMT2B BRPF1 BRD7 BRD9 KMT2A PWWP3A PIWIL2 TEX15 KDM5D BCOR ARID1A MBD2 DNMT1	6.81e-08	896	82	17	GO:0006325
GeneOntologyBiologicalProcess	facultative heterochromatin formation	JARID2 KMT2B KMT2A TEX15 MBD2 DNMT1	8.14e-08	55	82	6	GO:0140718
GeneOntologyBiologicalProcess	chromatin remodeling	RIOX2 JARID2 KMT2D KMT2B BRPF1 BRD7 BRD9 KMT2A PIWIL2 TEX15 KDM5D BCOR ARID1A MBD2 DNMT1	1.98e-07	741	82	15	GO:0006338
GeneOntologyBiologicalProcess	heterochromatin formation	JARID2 KMT2D KMT2B KMT2A PIWIL2 TEX15 MBD2 DNMT1	2.78e-07	163	82	8	GO:0031507
GeneOntologyBiologicalProcess	protein-DNA complex organization	RIOX2 JARID2 KMT2D SLF1 KMT2B BRPF1 BRD7 BRD9 KMT2A PWWP3A PIWIL2 TEX15 KDM5D BCOR ARID1A MBD2 DNMT1	3.20e-07	999	82	17	GO:0071824
GeneOntologyBiologicalProcess	epigenetic regulation of gene expression	JARID2 KMT2D KMT2B BRD7 KMT2A PIWIL2 TEX15 ARID1A MBD2 DNMT1	7.40e-07	330	82	10	GO:0040029
GeneOntologyBiologicalProcess	DNA methylation-dependent constitutive heterochromatin formation	KMT2B KMT2A TEX15 MBD2 DNMT1	8.44e-07	44	82	5	GO:0006346
GeneOntologyBiologicalProcess	negative regulation of gene expression, epigenetic	JARID2 KMT2D KMT2B KMT2A PIWIL2 TEX15 MBD2 DNMT1	1.47e-06	203	82	8	GO:0045814
GeneOntologyBiologicalProcess	transposable element silencing by mRNA destabilization	TUT7 PIWIL2	1.55e-04	5	82	2	GO:0141008
GeneOntologyBiologicalProcess	transposable element silencing by piRNA-mediated heterochromatin formation	PIWIL2 TEX15	2.32e-04	6	82	2	GO:0141006
GeneOntologyBiologicalProcess	piRNA-mediated heterochromatin formation	PIWIL2 TEX15	3.24e-04	7	82	2	GO:0140966
GeneOntologyCellularComponent	transferase complex	CDK8 JARID2 NAA35 KMT2D POLR3D SLF1 KMT2B ERN1 BRPF1 KMT2A CAB39L KLHL41 BCOR SNRPG XRCC6	3.77e-06	963	81	15	GO:1990234
GeneOntologyCellularComponent	methyltransferase complex	JARID2 KMT2D KMT2B KMT2A SNRPG	6.29e-05	108	81	5	GO:0034708
GeneOntologyCellularComponent	histone methyltransferase complex	JARID2 KMT2D KMT2B KMT2A	2.06e-04	75	81	4	GO:0035097
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	BRD7 BRD9 ARID1A MBD2	5.30e-04	96	81	4	GO:0070603
GeneOntologyCellularComponent	nuclear protein-containing complex	CDK8 JARID2 KMT2D POLR3D KMT2B BRD7 BRD9 KMT2A CPSF2 BCOR ARID1A MBD2 SNRPG XRCC6	7.69e-04	1377	81	14	GO:0140513
MousePheno	abnormal circulating LDL cholesterol level	CT45A6 CT45A1 CT45A3 CT45A10 BRD7 CT45A2 KIT CT45A7 CT45A9	2.44e-08	163	59	9	MP:0000181
MousePheno	increased circulating LDL cholesterol level	CT45A6 CT45A1 CT45A3 CT45A10 CT45A2 CT45A7 CT45A9	4.13e-08	80	59	7	MP:0000182
MousePheno	abnormal circulating non-HDL cholesterol level	CT45A6 CT45A1 CT45A3 CT45A10 BRD7 CT45A2 KIT CT45A7 CT45A9	5.75e-08	180	59	9	MP:0020151
MousePheno	increased circulating HDL cholesterol level	CT45A6 CT45A1 CT45A3 CT45A10 BRD9 CT45A2 CT45A7 CT45A9	6.58e-06	238	59	8	MP:0001556
MousePheno	increased circulating cholesterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD9 CT45A2 TRAPPC10 CT45A7 CT45A9	2.11e-05	463	59	10	MP:0005178
MousePheno	increased cholesterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD9 CT45A2 TRAPPC10 CT45A7 CT45A9	4.21e-05	502	59	10	MP:0003982
MousePheno	increased sterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD9 CT45A2 TRAPPC10 CT45A7 CT45A9	4.43e-05	505	59	10	MP:0012226
MousePheno	abnormal circulating lipoprotein level	CT45A6 CT45A1 CT45A3 CT45A10 BRD7 BRD9 CT45A2 KIT CT45A7 CT45A9	6.96e-05	533	59	10	MP:0010330
MousePheno	abnormal lipoprotein level	CT45A6 CT45A1 CT45A3 CT45A10 BRD7 BRD9 CT45A2 KIT CT45A7 CT45A9	6.96e-05	533	59	10	MP:0010329
MousePheno	abnormal DNA methylation	KMT2B USP29 PIWIL2 DNMT1	7.18e-05	53	59	4	MP:0008877
MousePheno	abnormal cholesterol homeostasis	CT45A6 CT45A1 POLR3D KMT2B CT45A3 CT45A10 BRD7 BRD9 CT45A2 TRAPPC10 KIT CT45A7 CT45A9	1.13e-04	936	59	13	MP:0005278
MousePheno	abnormal circulating HDL cholesterol level	CT45A6 CT45A1 CT45A3 CT45A10 BRD9 CT45A2 KIT CT45A7 CT45A9	1.22e-04	460	59	9	MP:0000184
MousePheno	liver hypoplasia	JARID2 LIG1 ERN1 KMT2A	1.33e-04	62	59	4	MP:0000600
MousePheno	abnormal circulating cholesterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD7 BRD9 CT45A2 TRAPPC10 KIT CT45A7 CT45A9	1.38e-04	823	59	12	MP:0000180
MousePheno	abnormal epigenetic regulation of gene expression	KMT2B USP29 PIWIL2 DNMT1	2.13e-04	70	59	4	MP:0012167
MousePheno	abnormal cholesterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD7 BRD9 CT45A2 TRAPPC10 KIT CT45A7 CT45A9	2.24e-04	867	59	12	MP:0003947
MousePheno	abnormal sterol level	CT45A6 CT45A1 KMT2B CT45A3 CT45A10 BRD7 BRD9 CT45A2 TRAPPC10 KIT CT45A7 CT45A9	2.57e-04	880	59	12	MP:0012224
MousePheno	decreased erythrocyte cell number	JARID2 LIG1 LAMA4 KMT2A NXPE1 USP1 KIT	5.45e-04	340	59	7	MP:0002875
MousePheno	embryonic lethality during organogenesis, complete penetrance	JARID2 KMT2D KMT2B ERN1 BRPF1 KMT2A RAPGEF1 BCOR ARID1A KIT	6.29e-04	700	59	10	MP:0011098
Domain	INT_SG_DDX_CT_C	CT45A1 CT45A3 CT45A10 CT45A7 CT45A9	7.04e-11	8	80	5	PF15300
Domain	INT_SG_DDX_CT_C	CT45A1 CT45A3 CT45A10 CT45A7 CT45A9	7.04e-11	8	80	5	IPR029307
Domain	FYrich_C	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	IPR003889
Domain	FYrich_N	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	IPR003888
Domain	FYRC	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	SM00542
Domain	FYRN	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	SM00541
Domain	FYRN	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	PF05964
Domain	FYRC	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	PF05965
Domain	FYRC	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	PS51543
Domain	FYRN	KMT2D KMT2B KMT2A	7.52e-07	5	80	3	PS51542
Domain	EPHD	KMT2D KMT2B BRPF1 KMT2A	2.15e-06	22	80	4	PS51805
Domain	Znf_CXXC	KMT2B KMT2A DNMT1	1.22e-05	11	80	3	IPR002857
Domain	ZF_CXXC	KMT2B KMT2A DNMT1	1.22e-05	11	80	3	PS51058
Domain	zf-CXXC	KMT2B KMT2A DNMT1	1.22e-05	11	80	3	PF02008
Domain	DUF3512	BRD7 BRD9	1.81e-05	2	80	2	PF12024
Domain	MeTrfase_trithorax	KMT2B KMT2A	1.81e-05	2	80	2	IPR016569
Domain	DUF3512	BRD7 BRD9	1.81e-05	2	80	2	IPR021900
Domain	Znf_PHD-finger	KMT2D KMT2B BRPF1 KMT2A KDM5D	2.23e-05	79	80	5	IPR019787
Domain	BROMODOMAIN_2	BRPF1 BRD7 BRD9 KMT2A	2.80e-05	41	80	4	PS50014
Domain	BROMO	BRPF1 BRD7 BRD9 KMT2A	3.09e-05	42	80	4	SM00297
Domain	Bromodomain	BRPF1 BRD7 BRD9 KMT2A	3.09e-05	42	80	4	IPR001487
Domain	-	BRPF1 BRD7 BRD9 KMT2A	3.09e-05	42	80	4	1.20.920.10
Domain	-	JARID2 KDM5D ARID1A	3.32e-05	15	80	3	1.10.150.60
Domain	BRIGHT	JARID2 KDM5D ARID1A	3.32e-05	15	80	3	SM00501
Domain	ARID_dom	JARID2 KDM5D ARID1A	3.32e-05	15	80	3	IPR001606
Domain	ARID	JARID2 KDM5D ARID1A	3.32e-05	15	80	3	PS51011
Domain	ARID	JARID2 KDM5D ARID1A	3.32e-05	15	80	3	PF01388
Domain	PHD	KMT2D KMT2B BRPF1 KMT2A KDM5D	3.98e-05	89	80	5	SM00249
Domain	Znf_FYVE_PHD	KMT2D KMT2B PCLO BRPF1 KMT2A KDM5D	3.99e-05	147	80	6	IPR011011
Domain	Post-SET_dom	KMT2D KMT2B KMT2A	4.07e-05	16	80	3	IPR003616
Domain	PostSET	KMT2D KMT2B KMT2A	4.07e-05	16	80	3	SM00508
Domain	RmlC_Cupin	CT45A1 CT45A3 CT45A2	4.07e-05	16	80	3	IPR011051
Domain	POST_SET	KMT2D KMT2B KMT2A	4.07e-05	16	80	3	PS50868
Domain	Znf_PHD	KMT2D KMT2B BRPF1 KMT2A KDM5D	4.43e-05	91	80	5	IPR001965
Domain	ZF_PHD_2	KMT2D KMT2B BRPF1 KMT2A KDM5D	5.45e-05	95	80	5	PS50016
Domain	ZF_PHD_1	KMT2D KMT2B BRPF1 KMT2A KDM5D	5.73e-05	96	80	5	PS01359
Domain	zf-C5HC2	JARID2 KDM5D	1.80e-04	5	80	2	PF02928
Domain	Znf_C5HC2	JARID2 KDM5D	1.80e-04	5	80	2	IPR004198
Domain	PHD	KMT2D KMT2B KMT2A KDM5D	3.01e-04	75	80	4	PF00628
Domain	JMJC	RIOX2 JARID2 KDM5D	3.43e-04	32	80	3	PS51184
Domain	JmjC_dom	RIOX2 JARID2 KDM5D	3.43e-04	32	80	3	IPR003347
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PXYLP1	3.75e-04	7	80	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PXYLP1	3.75e-04	7	80	2	PS00616
Domain	JmjC	RIOX2 JARID2 KDM5D	3.76e-04	33	80	3	SM00558
Domain	His_Pase_clade-2	PPIP5K1 PXYLP1	4.99e-04	8	80	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PXYLP1	4.99e-04	8	80	2	PF00328
Domain	BROMODOMAIN_1	BRPF1 BRD7 BRD9	5.29e-04	37	80	3	PS00633
Domain	Bromodomain	BRPF1 BRD7 BRD9	5.73e-04	38	80	3	PF00439
Domain	SET	KMT2D KMT2B KMT2A	7.17e-04	41	80	3	PF00856
Domain	JmjN	JARID2 KDM5D	7.97e-04	10	80	2	SM00545
Domain	JMJN	JARID2 KDM5D	7.97e-04	10	80	2	PS51183
Domain	JmjN	JARID2 KDM5D	7.97e-04	10	80	2	PF02375
Domain	JmjN	JARID2 KDM5D	7.97e-04	10	80	2	IPR003349
Domain	SET	KMT2D KMT2B KMT2A	1.01e-03	46	80	3	SM00317
Domain	SET_dom	KMT2D KMT2B KMT2A	1.28e-03	50	80	3	IPR001214
Domain	SET	KMT2D KMT2B KMT2A	1.28e-03	50	80	3	PS50280
Domain	-	KMT2D KMT2B PCLO BRPF1 KMT2A KDM5D UBOX5	3.11e-03	449	80	7	3.30.40.10
Domain	His_PPase_superfam	PPIP5K1 PXYLP1	3.27e-03	20	80	2	IPR029033
Domain	-	PPIP5K1 PXYLP1	3.27e-03	20	80	2	3.40.50.1240
Domain	Znf_RING/FYVE/PHD	KMT2D KMT2B PCLO BRPF1 KMT2A KDM5D UBOX5	3.51e-03	459	80	7	IPR013083
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	RIOX2 KMT2D KMT2B BRPF1 KMT2A KDM5D ARID1A	7.98e-06	175	59	7	MM14941
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	JARID2 KMT2D KMT2B KMT2A ARID1A MBD2 DNMT1	8.71e-05	254	59	7	M27131
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	RIOX2 KMT2D KMT2B BRPF1 KMT2A KDM5D ARID1A	1.33e-04	272	59	7	M29619
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	JARID2 KMT2D KMT2B KMT2A DNMT1	2.56e-04	136	59	5	MM14848
Pubmed	Identification of cancer/testis-antigen genes by massively parallel signature sequencing.	CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9	9.94e-21	15	85	9	15905330
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	JARID2 KMT2D KMT2B BRPF1 BRD7 BRD9 KDM5D ARID1A DNMT1	1.90e-10	157	85	9	30186101
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	KMT2D BRD7 BRD9 KMT2A ARID1A MBD2	1.89e-08	69	85	6	28481362
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2D KMT2B KMT2A	5.63e-08	4	85	3	23129768
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2D KMT2B KMT2A	1.40e-07	5	85	3	26320581
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2D KMT2B KMT2A	1.40e-07	5	85	3	28609655
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	JARID2 LIG1 CRYBG2 KMT2D BRD7 KMT2A ANKRD28 ARID1A ARMCX3 DNMT1	2.29e-07	469	85	10	27634302
Pubmed	Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.	KMT2D KMT2B KMT2A	2.80e-07	6	85	3	24176642
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2D KMT2B KMT2A	2.80e-07	6	85	3	16199523
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RIOX2 BBX KMT2B BRPF1 BRD7 BRD9 KMT2A BCOR ARHGAP11A XRCC6 DNMT1	2.82e-07	608	85	11	36089195
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	JARID2 CT45A6 CT45A1 BBX CT45A3 CT45A10 BRD7 CT45A2 TRAPPC10 PXYLP1 ECI2 CDC6 C3orf20 CT45A7 CT45A9	3.11e-07	1242	85	15	30973865
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KMT2D BBX SLF1 KMT2B RPS10 KMT2A CPSF2 CDC6 BCOR ARHGAP11A ARID1A MBD2 SNRPG XRCC6 DNMT1	5.22e-07	1294	85	15	30804502
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2D KMT2B KMT2A	7.82e-07	8	85	3	23130995
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2D KMT2B KMT2A	7.82e-07	8	85	3	22266653
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2D KMT2B KMT2A	1.17e-06	9	85	3	22665483
Pubmed	Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.	KMT2D KMT2B KMT2A	1.17e-06	9	85	3	16951254
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KMT2A KDM5D MBD2 DNMT1	1.29e-06	33	85	4	26864203
Pubmed	ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.	JARID2 KMT2A DNMT1	1.67e-06	10	85	3	20569692
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	KMT2D KMT2B KMT2A	3.05e-06	12	85	3	27563068
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	BBX SLF1 RPS10 BRD7 BRD9 KMT2A RPS10P5 BCOR ARID1A SNRPG XRCC6 DNMT1	3.55e-06	954	85	12	36373674
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KMT2B KMT2A KDM5D	3.96e-06	13	85	3	24619213
Pubmed	Single cell RT-PCR on mouse embryos: a general approach for developmental biology.	LIG1 MBD2 DNMT1	3.96e-06	13	85	3	20300987
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CDK8 KMT2D BRD7 KMT2A BCOR ARID1A MBD2	4.41e-06	268	85	7	33640491
Pubmed	KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.	KMT2B KMT2A	5.90e-06	2	85	2	28723559
Pubmed	A case report on concurrent occurrence of systemic mastocytosis and myeloid sarcoma presenting with extensive skin involvements and the results of genetic study.	ARID1A KIT	5.90e-06	2	85	2	33327223
Pubmed	The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus.	MBD2 DNMT1	5.90e-06	2	85	2	19019634
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2D KMT2B	5.90e-06	2	85	2	35640156
Pubmed	A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness.	KIT DNMT1	5.90e-06	2	85	2	28869603
Pubmed	Characterization of the Functional Interplay between the BRD7 and BRD9 Homologues in mSWI/SNF Complexes.	BRD7 BRD9	5.90e-06	2	85	2	36484504
Pubmed	Global DNA methylation, DNMT1, and MBD2 in patients with systemic lupus erythematosus.	MBD2 DNMT1	5.90e-06	2	85	2	21078759
Pubmed	Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit.	USP1 KIT	5.90e-06	2	85	2	35045360
Pubmed	Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression.	LAMA4 KMT2A	5.90e-06	2	85	2	34958665
Pubmed	ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis.	BRD9 ARID1A	5.90e-06	2	85	2	39013863
Pubmed	Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.	KMT2D KMT2A	5.90e-06	2	85	2	26711341
Pubmed	Associations between aberrant DNA methylation and transcript levels of DNMT1 and MBD2 in CD4+T cells from patients with systemic lupus erythematosus.	MBD2 DNMT1	5.90e-06	2	85	2	23127209
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2D KMT2B	5.90e-06	2	85	2	35506254
Pubmed	Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.	KMT2D KMT2A	5.90e-06	2	85	2	24423662
Pubmed	The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells.	KIT DNMT1	5.90e-06	2	85	2	26085088
Pubmed	A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.	CT45A2 KMT2A	5.90e-06	2	85	2	20920256
Pubmed	Deoxyribonucleic acid methyltransferases and methyl-CpG-binding domain proteins in human endometrium and endometriosis.	MBD2 DNMT1	5.90e-06	2	85	2	21316665
Pubmed	Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis.	MBD2 DNMT1	5.90e-06	2	85	2	20937307
Pubmed	MBD2 is required for correct spatial gene expression in the gut.	MBD2 DNMT1	5.90e-06	2	85	2	17353267
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	CT45A6 CT45A1 KMT2D CT45A3 CT45A10 CT45A2 ARMCX3 CT45A7 CEMIP CT45A9	5.92e-06	674	85	10	37196079
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KMT2D PCLO BRD7 BRD9 BCOR ARID1A SNRPG DNMT1	6.12e-06	398	85	8	35016035
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	JARID2 KMT2B KMT2A KDM5D	6.47e-06	49	85	4	34368113
Pubmed	Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres.	LIG1 MBD2 DNMT1	7.71e-06	16	85	3	18784354
Pubmed	Human transcription factor protein interaction networks.	KMT2D BBX SLF1 KMT2B RPS10 BRD7 BRD9 KMT2A ANKRD28 CPSF2 BCOR ARID1A MBD2 XRCC6	9.08e-06	1429	85	14	35140242
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2D KMT2B KMT2A KDM5D	1.19e-05	57	85	4	18022353
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RIOX2 CT45A8 KMT2B PCLO RPS10 CT45A2 PIWIL2 ARHGAP11A XRCC6 CT45A9	1.27e-05	736	85	10	29676528
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CDK8 LIG1 KMT2D KMT2B BRD9 KMT2A BCOR ARID1A MBD2 SNRPG XRCC6 DNMT1	1.52e-05	1103	85	12	34189442
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	KMT2B BRD7 KMT2A ARID1A	1.56e-05	61	85	4	20305087
Pubmed	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	KMT2D KMT2B	1.77e-05	3	85	2	32544095
Pubmed	Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia.	KMT2A KIT	1.77e-05	3	85	2	16029447
Pubmed	MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.	MBD2 DNMT1	1.77e-05	3	85	2	10947852
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D KMT2A	1.77e-05	3	85	2	26902498
Pubmed	The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.	KMT2D KMT2B	1.77e-05	3	85	2	23358417
Pubmed	Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.	MBD2 DNMT1	1.77e-05	3	85	2	18414412
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2D KMT2A	1.77e-05	3	85	2	23932714
Pubmed	CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis.	KMT2A KIT	1.77e-05	3	85	2	32549410
Pubmed	MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.	KMT2D KMT2A	1.77e-05	3	85	2	23192982
Pubmed	Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.	KMT2D ARID1A	1.77e-05	3	85	2	27387124
Pubmed	TEX15 associates with MILI and silences transposable elements in male germ cells.	PIWIL2 TEX15	1.77e-05	3	85	2	32381626
Pubmed	Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia.	KMT2A DNMT1	1.77e-05	3	85	2	23990460
Pubmed	ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma.	RIOX2 CDC6	1.77e-05	3	85	2	32312832
Pubmed	Association between mRNA levels of DNMT1, DNMT3A, DNMT3B, MBD2 and LINE-1 methylation status in infants with tetralogy of Fallot.	MBD2 DNMT1	1.77e-05	3	85	2	23820632
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2D KMT2A	1.77e-05	3	85	2	30315824
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2D KMT2B KMT2A	1.82e-05	21	85	3	27626377
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIG1 KMT2D KMT2B BRPF1 TRAPPC10 KMT2A CPSF2 BCOR XRCC6 DNMT1	1.96e-05	774	85	10	15302935
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2D KMT2B KMT2A	2.10e-05	22	85	3	26886794
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2D KMT2B BRD7 BRD9 KMT2A BCOR ARID1A	2.52e-05	351	85	7	38297188
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	JARID2 BBX BRPF1 TUT7 BRD7 KDM5D ARID1A XRCC6 DNMT1 ZNF646	2.82e-05	808	85	10	20412781
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2D KMT2B	3.53e-05	4	85	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2D ARID1A	3.53e-05	4	85	2	34645806
Pubmed	DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.	MBD2 DNMT1	3.53e-05	4	85	2	20573497
Pubmed	Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.	KMT2D KMT2A	3.53e-05	4	85	2	22863532
Pubmed	MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.	KMT2D KMT2B	3.53e-05	4	85	2	20808952
Pubmed	Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice.	KMT2D KMT2B	3.53e-05	4	85	2	23826075
Pubmed	Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma.	KMT2D ARID1A	3.53e-05	4	85	2	26138514
Pubmed	KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition.	KMT2D KMT2A	3.53e-05	4	85	2	37722486
Pubmed	Two mouse piwi-related genes: miwi and mili.	PIWIL2 KIT	3.53e-05	4	85	2	11578866
Pubmed	Efficiency assessment of the gene trap approach.	JARID2 RAPGEF1	3.53e-05	4	85	2	9626493
Pubmed	Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.	KMT2B KMT2A	3.53e-05	4	85	2	17166833
Pubmed	Sex-specific windows for high mRNA expression of DNA methyltransferases 1 and 3A and methyl-CpG-binding domain proteins 2 and 4 in human fetal gonads.	MBD2 DNMT1	3.53e-05	4	85	2	16998846
Pubmed	Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.	KMT2A KIT	3.53e-05	4	85	2	27396339
Pubmed	Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.	KMT2B KMT2A	3.53e-05	4	85	2	34156981
Pubmed	Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.	MBD2 DNMT1	3.53e-05	4	85	2	19109157
Pubmed	WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.	KMT2B KMT2A	3.53e-05	4	85	2	18840606
Pubmed	Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1.	LIG1 DNMT1	3.53e-05	4	85	2	36928068
Pubmed	Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.	KMT2B KMT2A	3.53e-05	4	85	2	26267306
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2D KMT2A	3.53e-05	4	85	2	24081332
Pubmed	BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation.	BRD9 KIT	3.53e-05	4	85	2	38816579
Pubmed	MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.	KMT2B KMT2A	3.53e-05	4	85	2	31534153
Pubmed	Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.	KMT2B KMT2A	3.53e-05	4	85	2	25834037
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRPF1 BRD7 BRD9 KMT2A	3.54e-05	75	85	4	25593309
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	LIG1 KMT2A ARID1A XRCC6 DNMT1	4.31e-05	157	85	5	30686591
Pubmed	An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.	BRD7 BRD9 ARID1A	4.92e-05	29	85	3	19279220
Pubmed	Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.	BRD7 BRD9 ARID1A	5.45e-05	30	85	3	31043422
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	CDK8 KMT2D ARID1A MBD2 XRCC6	5.78e-05	167	85	5	20362541
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	KMT2B KMT2A	5.87e-05	5	85	2	25561738
Pubmed	A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.	TUT7 PIWIL2	5.87e-05	5	85	2	30617251
Interaction	H3C14 interactions	CDK8 KMT2D KMT2B BRPF1 BRD7 KMT2A PWWP3A	3.13e-06	156	81	7	int:H3C14
Cytoband	Ensembl 112 genes in cytogenetic band chrXq26	CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9	3.60e-11	171	85	9	chrXq26
Cytoband	Xq26.3	CT45A6 CT45A1 CT45A3 CT45A5 CT45A2	1.70e-07	67	85	5	Xq26.3
Cytoband	6q16.1-q16.3	GPR63 FHL5	1.02e-05	3	85	2	6q16.1-q16.3
Cytoband	3p25.1	ANKRD28 C3orf20	1.94e-03	35	85	2	3p25.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3p25	BRPF1 ANKRD28 C3orf20	3.04e-03	155	85	3	chr3p25
GeneFamily	PHD finger proteins	KMT2D KMT2B BRPF1 KMT2A KDM5D	3.19e-06	90	46	5	88
GeneFamily	Zinc fingers CXXC-type	KMT2B KMT2A DNMT1	3.34e-06	12	46	3	136
GeneFamily	AT-rich interaction domain containing	JARID2 KDM5D ARID1A	6.86e-06	15	46	3	418
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D KMT2B KMT2A	8.73e-05	34	46	3	487
GeneFamily	PWWP domain containing	BRPF1 PWWP3A	1.42e-03	22	46	2	1147
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	KDM5D TMSB4Y	7.46e-03	51	46	2	870
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_1_CELL	CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9	9.95e-13	69	83	9	M45681
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL	CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9	4.41e-11	104	83	9	M45682
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9	5.33e-07	157	84	6	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9	8.48e-07	170	84	6	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9	1.62e-06	190	84	6	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9	1.62e-06	190	84	6	71a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9	1.77e-06	193	84	6	2f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	LIG1 TUT7 GNPNAT1 CDC6 ARID1A USP1	2.18e-06	200	84	6	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	LIG1 TUT7 GNPNAT1 CDC6 ARID1A USP1	2.18e-06	200	84	6	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CT45A6 CT45A1 CT45A10 CT45A2 CT45A9	1.31e-05	160	84	5	5cd4fbbd2ce671a8377416eff94041a111375dee
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 KIT DNMT1	1.97e-05	174	84	5	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	SULT1B1 TBC1D1 CPSF2 BCOR UBOX5	2.78e-05	187	84	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KMT2D FASTKD1 POLI KDM5D BCOR	3.00e-05	190	84	5	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIG1 SLF1 CDC6 USP1 DNMT1	3.08e-05	191	84	5	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KMT2D FASTKD1 POLI KDM5D BCOR	3.16e-05	192	84	5	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.32e-05	194	84	5	4c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.40e-05	195	84	5	7ae732f100e9a3c6062be5b877efa1ec9d5b3958
ToppCell	facs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.40e-05	195	84	5	93c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LIG1 SLF1 CDC6 USP1 DNMT1	3.40e-05	195	84	5	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	normal_Lung-T/NK_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.65e-05	198	84	5	c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.65e-05	198	84	5	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	remission-T/NK_proliferative\|World / disease stage, cell group and cell class	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	f305f3a454b7d2170429bad087480ccccca19acd
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	4394dcd1809f49e9bada8f5e115d5123356eae3e
ToppCell	remission-T/NK_proliferative\|remission / disease stage, cell group and cell class	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	303a5fc43a48b05b6f2060d99eef4adc36f8d4e3
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Convalescent / Disease group, lineage and cell class	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	893b78c661c529db07a5fcc3124d9b3d0f270fa5
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	c0ea391bb347b99b94b5d7f02612ede938986745
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	LIG1 TUT7 CDC6 ARID1A USP1	3.74e-05	199	84	5	fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	5b18e18ddbf4bd53aa0d574d23092cb96da7f400
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	6df65f4c2f9a125e0c7c4f597fefc05a97fc8831
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	cb229aa3eb7b1cc47e76711b8fc18fce88a5cf08
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	LIG1 TUT7 CDC6 ARID1A USP1	3.74e-05	199	84	5	91882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIG1 CDC6 USP1 SNRPG DNMT1	3.74e-05	199	84	5	96af1f289552f38f2dfa181192eb3276f4c7d70b
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Convalescent / Disease, condition lineage and cell class	LIG1 CDC6 USP1 SNRPG DNMT1	3.83e-05	200	84	5	00538c4cbab5da00b3a366717d38a3ba5cfe3f65
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	548a0f486ab8745da107f2815914dbf873a6e3c8
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells-Neuroepithelial_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	55501f83409e0174c756a13ad8077f5b59975e27
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells\|6m / Sample Type, Dataset, Time_group, and Cell type.	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	b9aad527d3ad5bc701e93fa2afdebf695b2a74bb
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	5b014c658eecc5e73679e5feb7a2aaa3d297001d
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-T/NK_proliferative\|Leuk-UTI / Disease, condition lineage and cell class	LIG1 CDC6 ARHGAP11A USP1 DNMT1	3.83e-05	200	84	5	093e97395be23092229521cc55aaaee8befbc149
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-T/NK_proliferative\|Bac-SEP / Disease, condition lineage and cell class	LIG1 GPR63 CDC6 ARHGAP11A USP1	3.83e-05	200	84	5	a09b4e07b273880e94032b939ab191caaf6d656e
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCA1L USP29 C2CD6 CEMIP	1.31e-04	137	84	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCA1L USP29 C2CD6 CEMIP	1.31e-04	137	84	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 KIT	1.68e-04	146	84	4	2d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Nrip3_(CA1_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR63 PIWIL2 C3orf20	1.89e-04	59	84	3	172f1c6fdc8005a6f21d68a4dc0f8631c265d9e5
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	BRD7 TRAPPC10 DGKB MBD2	2.06e-04	154	84	4	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIOX2 LIG1 SNRPG DNMT1	2.22e-04	157	84	4	eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 DNMT1	2.33e-04	159	84	4	a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CRYBG2 CDC6 DNMT1	2.38e-04	160	84	4	ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	JARID2 TUT7 RAPGEF1 MBD2	2.38e-04	160	84	4	6ed37d1fd0304932319d6b942502404115ff36a7
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 ERN1 SERINC5 ARMCX3	2.56e-04	163	84	4	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Lung / Manually curated celltypes from each tissue	LIG1 GPR63 CDC6 ARHGAP11A	2.56e-04	163	84	4	47300dec94dc66e965bf71fafff0a9fd24fae968
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 ERN1 SERINC5 ARMCX3	2.56e-04	163	84	4	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLF1 EFCAB13 DGKB CDC6	2.74e-04	166	84	4	26f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 GPR63 CDC6 USP1	2.80e-04	167	84	4	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 DNMT1	2.93e-04	169	84	4	20fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 TEX15 CDC6 USP1	3.00e-04	170	84	4	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ERN1 KDM5D ARHGAP11A TMSB4Y	3.07e-04	171	84	4	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 DNMT1	3.28e-04	174	84	4	66555c610251ea04f968c258e312d720c18e7cde
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LIG1 PCLO CDC6 ARHGAP11A	3.35e-04	175	84	4	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	LIG1 PCLO CDC6 ARHGAP11A	3.35e-04	175	84	4	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PCLO PWWP3A CAB39L KIT	3.50e-04	177	84	4	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 KIT DNMT1	3.50e-04	177	84	4	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCA1L KIAA1328 GPR63 KIT	3.50e-04	177	84	4	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ERN1 KIAA1328 GPR63 CEMIP	3.50e-04	177	84	4	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 TNNI1 DNMT1	3.57e-04	178	84	4	79823d13652177de852c2acce9159049241f1d86
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 KMT2A RAPGEF1 ANKRD28	3.88e-04	182	84	4	a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 KMT2A RAPGEF1 ANKRD28	3.88e-04	182	84	4	626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th17\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 RPS10 ANKRD28 KIT	3.96e-04	183	84	4	1ee09af56dac121c841d869021ca625dd3336b84
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	USP29 CDC6 ARHGAP11A USP1	3.96e-04	183	84	4	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	Bac-SEP-Lymphocyte-T_NK-T_NK_proliferative\|Bac-SEP / Disease, Lineage and Cell Type	LIG1 GPR63 CDC6 ARHGAP11A	4.05e-04	184	84	4	848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 RPS10 ARHGAP11A DNMT1	4.22e-04	186	84	4	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 RPS10 ARHGAP11A DNMT1	4.22e-04	186	84	4	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 PXYLP1 USP1 DNMT1	4.30e-04	187	84	4	14c239af77116d28d511dea754b6150d20488080
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NOX3 CATSPERB TEX15 ARHGAP11A	4.39e-04	188	84	4	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETFDH KLHL41 UBOX5 XRCC6	4.39e-04	188	84	4	ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD28 PXYLP1 KIT ARMCX3	4.39e-04	188	84	4	e079a3873cf442e98ff41a240c80b80995aace11
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETFDH KLHL41 UBOX5 XRCC6	4.39e-04	188	84	4	40ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 USP1 DNMT1	4.84e-04	193	84	4	40eedc1490c113403bc7c12a6bdf976f4f8bca84
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	SERINC5 CPSF2 CDC6 CEMIP	4.84e-04	193	84	4	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RIOX2 SULT1B1 STON1 ARHGAP11A	4.84e-04	193	84	4	3091090abcf18b48eac7e6c85653c18aa54fcb9b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RIOX2 SULT1B1 STON1 ARHGAP11A	4.84e-04	193	84	4	a18770ceb770aaa4903dd04442ad0a73159ead9a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LIG1 CT45A1 CT45A10 CDC6	4.84e-04	193	84	4	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 SLF1 CDC6 DNMT1	4.84e-04	193	84	4	f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LIG1 CT45A1 CT45A10 CDC6	4.84e-04	193	84	4	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	P03-Endothelial-proliferative_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LIG1 CDC6 ARHGAP11A USP1	4.94e-04	194	84	4	22bcfb0f3f73608feb22c0847ab4d34f87aeede0
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 DNMT1	4.94e-04	194	84	4	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 CDC6 USP1 DNMT1	4.94e-04	194	84	4	ae6d5cf4c825b29e677296df2c0985431c83b82e
ToppCell	P03-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LIG1 CDC6 ARHGAP11A USP1	4.94e-04	194	84	4	5e56ce9b9fe0721be3a9e6efe1422599bb867721
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LIG1 CDC6 ARHGAP11A USP1	4.94e-04	194	84	4	8f313071933451780309d2174ed27d8cdc734343
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LIG1 SLF1 CDC6 DNMT1	5.04e-04	195	84	4	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LIG1 CDC6 ARHGAP11A USP1	5.04e-04	195	84	4	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LIG1 CDC6 ARHGAP11A USP1	5.04e-04	195	84	4	1a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 USP1 DNMT1	5.04e-04	195	84	4	043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LIG1 CDC6 USP1 DNMT1	5.04e-04	195	84	4	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LIG1 SLF1 CDC6 DNMT1	5.13e-04	196	84	4	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	cycling_basal_cell\|World / shred by cell class for nasal brushing	LIG1 ECI2 CDC6 ARHGAP11A	5.13e-04	196	84	4	aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 ARHGAP11A USP1 DNMT1	5.13e-04	196	84	4	5ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell	ICU-SEP-Lymphocyte-T_NK-T_NK_proliferative\|ICU-SEP / Disease, Lineage and Cell Type	LIG1 CDC6 ARHGAP11A DNMT1	5.23e-04	197	84	4	908e91fa16134b61943aea5e8fc0d6fbac8a8c6e
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2A SERINC5 TNNI1 C3orf20	5.23e-04	197	84	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Large_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LIG1 CDC6 ARHGAP11A USP1	5.23e-04	197	84	4	cebf47d66f425c84d3fea962e11f5bf4bfe2e60f
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 CDC6 USP1 DNMT1	5.23e-04	197	84	4	a0d463825b62de49466f9fa563405dda4387cfff
Disease	choline deficiency disease (implicated_via_orthology)	MBD2 DNMT1	5.71e-06	2	71	2	DOID:8456 (implicated_via_orthology)
Disease	choline deficiency disease (biomarker_via_orthology)	MBD2 DNMT1	1.71e-05	3	71	2	DOID:8456 (biomarker_via_orthology)
Disease	DNA polymerase iota measurement	POLI MBD2	1.71e-05	3	71	2	EFO_0802476
Disease	Sezary Syndrome	KMT2D BRD9 ARID1A	3.75e-05	27	71	3	C0036920
Disease	Acute myelomonocytic leukemia	KMT2A KIT	5.68e-05	5	71	2	C0023479
Disease	Embryonal Rhabdomyosarcoma	BCOR ARID1A	1.58e-04	8	71	2	C0206656
Disease	Bladder Neoplasm	LIG1 KMT2D KMT2A ARID1A	3.69e-04	140	71	4	C0005695
Disease	Malignant neoplasm of urinary bladder	LIG1 KMT2D KMT2A ARID1A	3.79e-04	141	71	4	C0005684
Disease	cancer (implicated_via_orthology)	LIG1 GNPNAT1 CAB39L ARID1A KIT	4.75e-04	268	71	5	DOID:162 (implicated_via_orthology)
Disease	prostate cancer (is_marker_for)	KMT2D KMT2B KMT2A DNMT1	5.55e-04	156	71	4	DOID:10283 (is_marker_for)
Disease	congenital heart disease (implicated_via_orthology)	KMT2D KMT2B KMT2A	6.24e-04	69	71	3	DOID:1682 (implicated_via_orthology)
Disease	T-Cell Lymphoma	KMT2D ARID1A	6.70e-04	16	71	2	C0079772
Disease	syndromic intellectual disability (implicated_via_orthology)	BRPF1 KDM5D	6.70e-04	16	71	2	DOID:0050888 (implicated_via_orthology)
Disease	Prostatic Neoplasms	KMT2D BRPF1 KMT2A NOX3 ARID1A MBD2 DNMT1	6.99e-04	616	71	7	C0033578
Disease	Malignant neoplasm of prostate	KMT2D BRPF1 KMT2A NOX3 ARID1A MBD2 DNMT1	6.99e-04	616	71	7	C0376358
Disease	hypertrophic cardiomyopathy (is_marker_for)	KLHL41 DNMT1	7.58e-04	17	71	2	DOID:11984 (is_marker_for)
Disease	acute lymphoblastic leukemia, response to antineoplastic agent	DGKB NOX3	9.51e-04	19	71	2	EFO_0000220, GO_0097327
Disease	Chronic myeloproliferative disorder	CDC6 KIT	9.51e-04	19	71	2	C1292778
Disease	acute myeloid leukemia (is_implicated_in)	BRD7 KMT2A KIT	1.11e-03	84	71	3	DOID:9119 (is_implicated_in)
Disease	alcohol use disorder (implicated_via_orthology)	BRD7 BRD9 KDM5D ARID1A	1.27e-03	195	71	4	DOID:1574 (implicated_via_orthology)
Disease	nevus count, cutaneous melanoma	JARID2 STON1 RAPGEF1	1.39e-03	91	71	3	EFO_0000389, EFO_0004632
Disease	Adenocarcinoma of lung (disorder)	ERN1 GNPNAT1 SNRPG XRCC6	1.56e-03	206	71	4	C0152013
Disease	fasting blood glucose measurement, HOMA-B, fasting blood insulin measurement	ETFDH DGKB	1.65e-03	25	71	2	EFO_0004465, EFO_0004466, EFO_0004469
Disease	Bilateral Wilms Tumor	BCOR ARID1A	2.22e-03	29	71	2	C2930471
Disease	glucose measurement	ERN1 EFCAB13 ETFDH DGKB PXYLP1	2.24e-03	380	71	5	EFO_0004468

Protein segments in the cluster

Peptide	Gene	Start	Entry
MKKMPLFSKSHKNPA	CAB39L	1	Q9H9S4
KSKMDRHGNDKSTPK	BBX	456	Q8WY36
SKPIPRNMFHMSKKT	CATSPERB	891	Q9H7T0
QKTLKKPRSSLGMHM	C2orf78	616	A6NCI8
KTKHDLMMKGEGSRK	CPSF2	436	Q9P2I0
KMARAKTVMNSKTHP	DNMT1	336	P26358
IIKHPMDFSTMKEKI	BRD7	171	Q9NPI1
IIKHPMDFGTMKDKI	BRD9	176	Q9H8M2
MKSKDGKTPLHMTAL	ANKRD28	301	O15084
AMSKEKKLMTGHAIP	CT45A5	51	P0DMU8
DASKADHMKKMAPTV	BCOR	451	Q6W2J9
DMARKAMTKLGSKHF	CEMIP	246	Q8WUJ3
AMSKEKKLMTGHAIP	CT45A7	51	P0DMV0
KVGKFMAKLAEHMFP	ARMCX3	361	Q9UH62
KLMSVESKKMPIHFQ	CCDC83	371	Q8IWF9
PSKSPFLHSGMKMQK	ARID1A	1601	O14497
KMIKEGFRMLSPEHA	KIT	881	P10721
AMSKEKKLMTGHAIP	CT45A10	51	P0DMU9
MGLGLMAKDKDKTVH	KDM5D	246	Q9BY66
TSDYEMHKMRPKKIK	C2CD6	606	Q53TS8
RTDLKEEHKSSMMPG	PCLO	141	Q9Y6V0
AMSKEKKLMTGHAIP	CT45A3	51	Q8NHU0
MKIPRSMFGVAVHKG	KLHL41	481	O60662
PMAMRFRHLKKTSKE	KMT2B	2561	Q9UMN6
LSPLKSTRKKMGMHR	KIAA1328	546	Q86T90
STRKKMGMHRTPEEL	KIAA1328	551	Q86T90
FDFRTGKMMPSKLQK	MBD2	206	Q9UBB5
FMNVPKIKGTHTAMK	ETFDH	391	Q16134
AMSKAKKLMTGHAIP	CT45A1	51	Q5HYN5
AMSKEKKLMTGHAIP	CT45A9	51	P0DMV2
KRTIMPGSRKMEFKG	FHL5	106	Q5TD97
KMIAMDPQKRPSAKH	ERN1	811	O75460
AKMPSHLMLARKGDS	C3orf20	316	Q8ND61
AMSKEKKLMTGHAIP	CT45A2	51	Q5DJT8
SPLEMMKKHVAGTKG	CRYBG2	871	Q8N1P7
IPHMKGKSAMKKRHL	FASTKD1	791	Q53R41
IMREKHPEKFNSRMK	DGKB	601	Q9Y6T7
SRPAGKDMMRKLEKH	CDC6	256	Q99741
DFLMKMKESPHFQKS	EFCAB13	816	Q8IY85
AMSKEKKLMTGHAIP	CT45A8	51	P0DMV1
VSPEQFMKSFEHMKK	GNPNAT1	66	Q96EK6
MPMRFRHLKKTSKEA	KMT2A	3816	Q03164
KKFHDACLDMMPKSF	GPR63	376	Q9BZJ6
MSPAKATEMLIFGKK	ECI2	291	O75521
KKMPEHSTLMKDFRR	CDK8	271	P49336
MQRSIMSFFHPKKEG	LIG1	1	P18858
SRSGKHSFKMKDTHM	POLI	461	Q9UNA4
HSFKMKDTHMEDFPK	POLI	466	Q9UNA4
AMSKEKKLMTGHAIP	CT45A6	51	P0DMU7
FHRSKVGVEMMKDRK	NXPE1	276	Q8N323
RHVKSMDNEKMKIPF	LAMA4	1156	Q16363
EMKRRHIAKPFSMEK	JARID2	1046	Q92833
GHMNPKMKGFTVSLK	PWWP3A	446	Q2TAK8
MELPSKSFLKMRKHP	ARHGAP11A	921	Q6P4F7
KKMKATNEPSLTHMD	UBOX5	401	O94941
HSIFEQGPAEMMKKK	POLR3D	106	P05423
ELSFMTGIPEKMKKD	PIWIL2	496	Q8TC59
YFKTPLGKKSMKHRM	IQCA1L	786	A6NCM1
KNGMSSKSRKRIMPD	PXYLP1	36	Q8TE99
LELHMKKRGFKMAPG	NOX3	306	Q9HBY0
TTVMDHSKSPFMRKG	SULT1B1	246	O43704
LDHIKKPMDFFTMKQ	BRPF1	666	P55201
RNGHEAPMTKIKKLM	ZNF525	106	Q8N782
FKEGVMVAKKDVHMP	RPS10	16	P46783
DDKRKMPFTEKIMAT	XRCC6	441	P12956
MKPHKSTKLVSGFLM	ZNF671	266	Q8TAW3
KTMVAFDMDGKVRKP	NAA35	591	Q5VZE5
FKEGVMVAKKDVHMP	RPS10P5	16	Q9NQ39
MSKAHPPELKKFMDK	SNRPG	1	P62308
PGSKKMFSSRNKEMP	STON1	201	Q9Y6Q2
SSFTMKLMDKFHSPK	RAPGEF1	11	Q13905
MSDKPGMAEIEKFDK	TMSB4Y	1	O14604
KMKEHIPFFEDMCKG	SERINC5	61	Q86VE9
KGKQAMPEKHESEMS	TMEM131	1446	Q92545
KMLSTPGRSKIKFDM	TBC1D1	776	Q86TI0
PGRSKIKFDMEKMHS	TBC1D1	781	Q86TI0
GKDFSNPMALKSHMR	ZNF646	81	O15015
MEGRKKMFDAAKSPT	TNNI1	171	P19237
MPLFMSKSPTHVKKG	USP29	146	Q9HBJ7
DSNSHSMKKDLVMPK	TEX13C	831	A0A0J9YWL9
AEMFAMPRDLKGSKK	nan	11	A6NLC8
LSSDMKKDFIMHRLP	RIOX2	326	Q8IUF8
PKHIIQMTGFKMEEK	SLF1	6	Q9BQI6
MSAPRKDLGKMAHIR	TEX15	2216	Q9BXT5
DMLGMAEPHRKHKDK	TRAPPC10	896	P48553
GKIGHFMKDCPMRRK	TUT7	1351	Q5VYS8
KQKMKMEVKHPRFFA	PPIP5K1	406	Q6PFW1
MDSMRHSEDFKEKLP	USP1	251	O94782
FKDKTMLCPMHKIKG	KMT2D	5126	O14686