Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	6.81e-08	431	37	9	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	3.22e-06	884	37	10	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR52E5 OR5H14 TAS2R8 GRIK5 OR5M9 OR6B3 OR6B2 ITGB2 OR4C6 OR9G4 OR51I2 OR1L4	3.37e-06	1353	37	12	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR5H14 OR5M9 OR6B3 OR6B2 OR9G4	3.56e-06	127	37	5	GO:0005549
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC5 SLC7A1 GRIK5 SLC38A9 SLC35B4 SLC10A4	1.50e-05	293	37	6	GO:0008514
GeneOntologyMolecularFunction	fatty acid elongase activity	ELOVL2 ELOVL7	6.97e-05	7	37	2	GO:0009922
GeneOntologyMolecularFunction	transporter activity	ABCC5 CACNA1S SLC7A1 SLC9A8 GRIK5 PIEZO2 XKR4 SLC38A9 SLC35B4 SLC10A4	8.47e-05	1289	37	10	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCC5 CACNA1S SLC7A1 SLC9A8 GRIK5 PIEZO2 SLC38A9 SLC35B4 SLC10A4	2.35e-04	1180	37	9	GO:0022857
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC7A1 SLC38A9	2.57e-04	13	37	2	GO:0061459
GeneOntologyMolecularFunction	virus receptor activity	SLC7A1 ITGB5 ITGB6	5.21e-04	85	37	3	GO:0001618
GeneOntologyMolecularFunction	exogenous protein binding	SLC7A1 ITGB5 ITGB6	5.39e-04	86	37	3	GO:0140272
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC7A1 GRIK5 SLC38A9 SLC10A4	5.67e-04	207	37	4	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC7A1 GRIK5 SLC38A9 SLC10A4	5.77e-04	208	37	4	GO:0005342
GeneOntologyMolecularFunction	basic amino acid transmembrane transporter activity	SLC7A1 SLC38A9	6.22e-04	20	37	2	GO:0015174
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC7A1 GRIK5 SLC38A9	9.64e-04	105	37	3	GO:0015171
GeneOntologyMolecularFunction	amide transmembrane transporter activity	ABCC5 SLC38A9	2.75e-03	42	37	2	GO:0042887
GeneOntologyMolecularFunction	molecular sensor activity	MICU2 SLC38A9	3.87e-03	50	37	2	GO:0140299
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9A8 GRIK5 SLC10A4	3.87e-03	171	37	3	GO:0015081
GeneOntologyMolecularFunction	integrin binding	ITGB2 ITGB5 ITGB6	4.13e-03	175	37	3	GO:0005178
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	ABCC5 SLC35B4	5.35e-03	59	37	2	GO:1901505
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	ABCC5 SLC35B4	5.35e-03	59	37	2	GO:0015932
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1S SLC9A8 GRIK5 PIEZO2 SLC10A4	7.24e-03	664	37	5	GO:0008324
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC7A1 SLC38A9	7.66e-03	71	37	2	GO:0015179
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR52E5 OR5H14 TAS2R8 OR5M9 PIEZO2 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	3.61e-09	582	37	11	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	9.29e-09	485	37	10	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	1.93e-08	524	37	10	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	2.90e-08	547	37	10	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus	OR52E5 OR5H14 TAS2R8 OR5M9 PIEZO2 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	3.34e-08	722	37	11	GO:0051606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	5.28e-08	432	37	9	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	9.89e-08	465	37	9	GO:0007608
GeneOntologyBiologicalProcess	sensory perception	OR52E5 OR5H14 TAS2R8 OR5M9 PIEZO2 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4 LARGE1	2.02e-07	1072	37	12	GO:0007600
GeneOntologyBiologicalProcess	fatty acid elongation, polyunsaturated fatty acid	ELOVL2 ELOVL7	6.54e-05	7	37	2	GO:0034626
GeneOntologyBiologicalProcess	fatty acid elongation, monounsaturated fatty acid	ELOVL2 ELOVL7	6.54e-05	7	37	2	GO:0034625
GeneOntologyBiologicalProcess	fatty acid elongation, unsaturated fatty acid	ELOVL2 ELOVL7	6.54e-05	7	37	2	GO:0019368
GeneOntologyBiologicalProcess	fatty acid elongation, saturated fatty acid	ELOVL2 ELOVL7	8.71e-05	8	37	2	GO:0019367
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	1.25e-04	1395	37	10	GO:0007186
GeneOntologyBiologicalProcess	very long-chain fatty acid biosynthetic process	ELOVL2 ELOVL7	2.41e-04	13	37	2	GO:0042761
GeneOntologyBiologicalProcess	fatty acid elongation	ELOVL2 ELOVL7	3.24e-04	15	37	2	GO:0030497
GeneOntologyBiologicalProcess	L-arginine transmembrane transport	SLC7A1 SLC38A9	3.24e-04	15	37	2	GO:1903826
GeneOntologyBiologicalProcess	basic amino acid transmembrane transport	SLC7A1 SLC38A9	5.25e-04	19	37	2	GO:1990822
GeneOntologyBiologicalProcess	long-chain fatty-acyl-CoA biosynthetic process	ELOVL2 ELOVL7	5.25e-04	19	37	2	GO:0035338
GeneOntologyBiologicalProcess	cell adhesion mediated by integrin	ITGB2 ITGB5 ITGB6	5.79e-04	91	37	3	GO:0033627
GeneOntologyBiologicalProcess	basic amino acid transport	SLC7A1 SLC38A9	7.07e-04	22	37	2	GO:0015802
GeneOntologyCellularComponent	integrin complex	ITGB2 ITGB5 ITGB6	2.44e-05	32	37	3	GO:0008305
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGB2 ITGB5 ITGB6	1.55e-04	59	37	3	GO:0098636
Domain	Olfact_rcpt	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	5.45e-08	393	37	9	IPR000725
Domain	Integrin_b_cyt	ITGB2 ITGB5 ITGB6	1.43e-07	6	37	3	SM01241
Domain	Integrin_b_cyt	ITGB2 ITGB5 ITGB6	1.43e-07	6	37	3	PF08725
Domain	Integrin_bsu_cyt_dom	ITGB2 ITGB5 ITGB6	1.43e-07	6	37	3	IPR014836
Domain	Integrin_B_tail	ITGB2 ITGB5 ITGB6	2.49e-07	7	37	3	SM01242
Domain	Integrin_B_tail	ITGB2 ITGB5 ITGB6	2.49e-07	7	37	3	PF07965
Domain	Integrin_bsu_tail	ITGB2 ITGB5 ITGB6	2.49e-07	7	37	3	IPR012896
Domain	INB	ITGB2 ITGB5 ITGB6	3.98e-07	8	37	3	SM00187
Domain	Integrin_beta	ITGB2 ITGB5 ITGB6	3.98e-07	8	37	3	PF00362
Domain	Integrin_bsu_VWA	ITGB2 ITGB5 ITGB6	3.98e-07	8	37	3	IPR002369
Domain	INTEGRIN_BETA	ITGB2 ITGB5 ITGB6	5.96e-07	9	37	3	PS00243
Domain	PSI_integrin	ITGB2 ITGB5 ITGB6	5.96e-07	9	37	3	PF17205
Domain	Integin_beta_N	ITGB2 ITGB5 ITGB6	5.96e-07	9	37	3	IPR033760
Domain	Integrin_bsu	ITGB2 ITGB5 ITGB6	5.96e-07	9	37	3	IPR015812
Domain	G_PROTEIN_RECEP_F1_2	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	6.34e-07	691	37	10	PS50262
Domain	GPCR_Rhodpsn	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	6.43e-07	692	37	10	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	4.71e-06	670	37	9	IPR017452
Domain	7tm_1	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	5.12e-06	677	37	9	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	5.64e-06	685	37	9	PS00237
Domain	Integrin_dom	ITGB2 ITGB5 ITGB6	1.60e-05	25	37	3	IPR032695
Domain	-	ITGB5 ITGB6	2.29e-05	4	37	2	1.20.5.630
Domain	ELO_CS	ELOVL2 ELOVL7	5.70e-05	6	37	2	IPR030457
Domain	ELO	ELOVL2 ELOVL7	7.97e-05	7	37	2	PF01151
Domain	ELO	ELOVL2 ELOVL7	7.97e-05	7	37	2	PS01188
Domain	ELO_fam	ELOVL2 ELOVL7	7.97e-05	7	37	2	IPR002076
Domain	PSI	ITGB2 ITGB5 ITGB6	8.96e-05	44	37	3	IPR016201
Domain	PSI	ITGB2 ITGB5 ITGB6	1.02e-04	46	37	3	SM00423
Domain	EGF_extracell	ITGB2 ITGB5 ITGB6	2.27e-04	60	37	3	IPR013111
Domain	EGF_2	ITGB2 ITGB5 ITGB6	2.27e-04	60	37	3	PF07974
Domain	-	ITGB2 ITGB5 ITGB6	4.21e-04	74	37	3	3.40.50.410
Domain	VWFA	ITGB2 ITGB5 ITGB6	5.69e-04	82	37	3	PS50234
Domain	VWA	ITGB2 ITGB5 ITGB6	6.11e-04	84	37	3	SM00327
Domain	VWF_A	ITGB2 ITGB5 ITGB6	9.85e-04	99	37	3	IPR002035
Domain	EGF_1	ITGB2 ITGB5 ITGB6	1.39e-02	255	37	3	PS00022
Domain	EGF-like_CS	ITGB2 ITGB5 ITGB6	1.48e-02	261	37	3	IPR013032
Domain	EGF_2	ITGB2 ITGB5 ITGB6	1.54e-02	265	37	3	PS01186
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	1.80e-07	417	31	9	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR52E5 OR5H14 TAS2R8 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	6.11e-07	636	31	10	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	1.71e-05	389	31	7	M14091
Pathway	PID_INTEGRIN_CS_PATHWAY	ITGB2 ITGB5 ITGB6	2.42e-05	26	31	3	M47
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	ITGB2 ITGB5 ITGB6	1.46e-04	47	31	3	M39829
Pathway	WP_ELONGATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	ELOVL2 ELOVL7	3.05e-04	12	31	2	MM17077
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNA1S ITGB5 ITGB6	5.62e-04	74	31	3	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA1S ITGB5 ITGB6	5.62e-04	74	31	3	M16376
Pathway	PID_INTEGRIN5_PATHWAY	ITGB5 ITGB6	6.24e-04	17	31	2	M212
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNA1S ITGB5 ITGB6	7.85e-04	83	31	3	M8728
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	ITGB2 ITGB5 ITGB6	8.42e-04	85	31	3	M16441
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNA1S ITGB5 ITGB6	9.94e-04	90	31	3	M835
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ELOVL2 ELOVL7	1.05e-03	22	31	2	MM15451
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY	ITGB5 ITGB6	1.15e-03	23	31	2	M47537
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	ITGB5 ITGB6	1.15e-03	23	31	2	M47720
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ELOVL2 ELOVL7	1.25e-03	24	31	2	M1016
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGB2 ITGB5 ITGB6	1.43e-03	102	31	3	M39577
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGB2 ITGB5 ITGB6	1.43e-03	102	31	3	MM15830
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY	ITGB5 ITGB6	1.47e-03	26	31	2	M47719
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY	ITGB5 ITGB6	1.71e-03	28	31	2	M47655
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ITGB5 ITGB6	1.96e-03	30	31	2	M47724
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY	ITGB5 ITGB6	1.96e-03	30	31	2	M47718
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ELOVL2 ELOVL7	2.23e-03	32	31	2	MM15446
Pathway	WP_HIPPOMERLIN_SIGNALING_DYSREGULATION	ITGB2 ITGB5 ITGB6	2.33e-03	121	31	3	M39823
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ELOVL2 ELOVL7	2.97e-03	37	31	2	M729
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	ITGB5 ITGB6	2.97e-03	37	31	2	M27134
Pathway	PID_UPA_UPAR_PATHWAY	ITGB2 ITGB5	3.81e-03	42	31	2	M174
Pathway	WP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS	ITGB5 ITGB6	4.00e-03	43	31	2	M39565
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	7.17e-11	340	37	9	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	7.17e-11	340	37	9	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	7.76e-11	343	37	9	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	8.38e-11	346	37	9	14611657
Pubmed	The human olfactory receptor gene family.	OR52E5 OR5H14 OR5M9 OR6B3 OR6B2 OR4C6 OR9G4 OR51I2 OR1L4	4.22e-09	541	37	9	14983052
Pubmed	Integrins.	ITGB2 ITGB5 ITGB6	2.42e-07	12	37	3	19693543
Pubmed	Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling.	ITGB2 ITGB6	1.10e-06	2	37	2	24175614
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGB2 ITGB5 ITGB6	3.19e-06	27	37	3	31541017
Pubmed	αVβ8 integrin targeting to prevent posterior capsular opacification.	ITGB5 ITGB6	3.30e-06	3	37	2	34554928
Pubmed	Direct integrin alphavbeta6-ERK binding: implications for tumour growth.	ITGB5 ITGB6	6.60e-06	4	37	2	11857080
Pubmed	αvβ3, αvβ5 and αvβ6 integrins in brain metastases of lung cancer.	ITGB5 ITGB6	6.60e-06	4	37	2	25150423
Pubmed	Comparing the expression of integrins αvβ3, αvβ5, αvβ6, αvβ8, fibronectin and fibrinogen in human brain metastases and their corresponding primary tumors.	ITGB5 ITGB6	6.60e-06	4	37	2	24294359
Pubmed	Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling.	SLC7A1 SLC38A9	1.10e-05	5	37	2	30956113
Pubmed	Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit.	ITGB2 ITGB5	1.10e-05	5	37	2	9442085
Pubmed	HIV-1-Tat protein promotes chemotaxis and invasive behavior by monocytes.	ITGB2 ITGB5	1.65e-05	6	37	2	8757599
Pubmed	Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.	ITGB5 ITGB6	1.65e-05	6	37	2	24216753
Pubmed	Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development.	ITGB5 ITGB6	1.65e-05	6	37	2	8601592
Pubmed	Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.	ITGB2 ITGB5 ITGB6	2.50e-05	53	37	3	1431091
Pubmed	Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin.	ITGB5 ITGB6	3.07e-05	8	37	2	16005200
Pubmed	The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes.	ITGB2 ITGB6	3.07e-05	8	37	2	10906324
Pubmed	ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.	ELOVL2 ELOVL7	4.93e-05	10	37	2	20937905
Pubmed	Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.	ELOVL2 ELOVL7	6.02e-05	11	37	2	23689133
Pubmed	Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.	ITGB2 ITGB5	7.22e-05	12	37	2	12606711
Pubmed	Enhancer interaction networks as a means for singular olfactory receptor expression.	OR9G4 OR1L4	9.94e-05	14	37	2	25417106
Pubmed	LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.	ABCC5 SLC7A1	1.15e-04	15	37	2	28112518
Pubmed	Integrin requirement for hippocampal synaptic plasticity and spatial memory.	ITGB5 ITGB6	1.31e-04	16	37	2	12904471
Pubmed	Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.	ABCC5 SLC7A1	1.67e-04	18	37	2	31791063
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ITGB2 ITGB5 ITGB6	1.72e-04	101	37	3	23382219
Pubmed	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	CKAP5 HARBI1	2.51e-04	22	37	2	20694011
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGB5 ITGB6	2.75e-04	23	37	2	23152823
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	ELOVL2 ELOVL7	3.80e-04	27	37	2	25269881
Pubmed	Biosynthesis of triacylglycerols.	ELOVL2 ELOVL7	4.09e-04	28	37	2	8944226
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	ITGB2 CYP46A1	5.35e-04	32	37	2	18842294
Pubmed	Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.	ITGB2 ITGB5	5.35e-04	32	37	2	23154389
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	CKAP5 DNAH6	6.41e-04	35	37	2	24515614
GeneFamily	CD molecules\|Integrin beta subunits	ITGB2 ITGB5 ITGB6	2.78e-07	9	28	3	1159
GeneFamily	Solute carriers	SLC7A1 SLC9A8 SLC38A9 SLC35B4 SLC10A4	3.15e-04	395	28	5	752
GeneFamily	Olfactory receptors, family 6	OR6B3 OR6B2	2.81e-03	51	28	2	153
GeneFamily	Olfactory receptors, family 5	OR5H14 OR5M9	1.29e-02	112	28	2	152
Coexpression	ALFANO_MYC_TARGETS	QSOX1 ABCC5 ITGB5 HERPUD1 LARGE1	1.36e-05	239	34	5	M2477
Computational	Genes in the cancer module 275.	ITGB2 ITGB5 ITGB6	1.50e-06	16	16	3	MODULE_275
Computational	Genes in the cancer module 412.	ITGB2 ITGB5	1.60e-04	13	16	2	MODULE_412
Disease	lifestyle measurement, alcohol consumption measurement	GRIK5 PIEZO2 ITGB2	3.45e-04	115	35	3	EFO_0007878, EFO_0010724
Disease	lifestyle measurement, anxiety disorder measurement	GRIK5 PIEZO2 ITGB2	5.75e-04	137	35	3	EFO_0007795, EFO_0010724
Disease	diastolic blood pressure change measurement	MICU2 XKR4	1.62e-03	50	35	2	EFO_0006945
Disease	coronary artery calcification	GRIK5 DNAH6 HERPUD1 ELOVL2	1.92e-03	450	35	4	EFO_0004723
Disease	adverse effect, response to xenobiotic stimulus	ELOVL2 LARGE1	2.24e-03	59	35	2	EFO_0009658, GO_0009410
Disease	response to ketamine	OR5H14 LARGE1	3.05e-03	69	35	2	EFO_0009748

Protein segments in the cluster

Peptide	Gene	Start	Entry
MALSAFMFLYYPPLD	DISP3	86	Q9P2K9
SESFFYDYMELASMP	CFAP44	106	Q96MT7
LYSLSFMGLLAMYTY	QSOX1	716	O00391
LYFYSSLSRFLMVMG	HERPUD1	281	Q15011
FIGSMYMFPLLYALF	SLC10A4	356	Q96EP9
LSVSLYYGPLAFMYM	OR5H14	246	A6NHG9
TPYMFLSDIDFLPMY	LARGE1	556	O95461
TDEYLMSMYGFPRQF	HARBI1	31	Q96MB7
YPVDLYYLMDLSASM	ITGB6	131	P18564
HEPMYYFLSMLSFSD	OR51I2	56	Q9H344
YPVDLYYLMDLSLSM	ITGB5	136	P18084
ISVMLFYGSLLFMYS	OR9G4	261	Q8NGQ1
PIDLYYLMDLSYSML	ITGB2	126	P05107
FILFYPAMMFASRLT	ABCC5	326	O15440
VMYLYVGPSLRMFFE	CKAP5	781	Q14008
MYFVIASLSEIDPMY	DNAH6	3301	Q9C0G6
LLFSTYVMGRMDTYF	CYP46A1	391	Q9Y6A2
MLDSYLPTFFLTVMY	ELOVL2	31	Q9NXB9
ILMYSYYGLSVFPSM	ELOVL2	181	Q9NXB9
PVFACIIMSYSFMFL	ELOVL7	236	A1L3X0
TSSYFEYLMFALIML	CACNA1S	1116	Q13698
SAMDIMYYTSPLYRD	DDHD1	486	Q8NEL9
TSAFYKYILTTMDFP	GRIK5	236	Q16478
LLKMFMDSESFYYSL	INPP5F	166	Q9Y2H2
FLLFQMMTVYPLLGY	SLC38A9	446	Q8NBW4
HRPMYYFLSSMSFLE	OR6B2	56	Q6IFH4
VIYVYFRPLSMYSVM	OR1L4	256	Q8NGR5
VMLAFYLPALFSFMT	OR52E5	246	Q8NH55
PMYFFLTFLSLLDVM	OR4C6	56	Q8NH72
IPIRYYAIMVTMFFT	SLC35B4	61	Q969S0
EYYMTPRDFLFSVMF	MICU2	101	Q8IYU8
SLEFGMMIIFAYLPY	SLC9A8	296	Q9Y2E8
VSMFYGTPIFMYLRR	OR5M9	246	Q8NGP3
HRPMYYFLSSMSFLE	OR6B3	56	Q8NGW1
YFGVSAALTLMMPYF	SLC7A1	301	P30825
MMLPSLTSSVYFFVF	PIEZO2	236	Q9H5I5
FSSFLTGVVFMLMYY	XKR4	496	Q5GH76
LYYISSILMTFSYLM	TAS2R8	246	Q9NYW2