Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNB4 GNB1 GNB2	1.91e-04	35	67	3	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNB4 GNB1 GNB2	3.07e-04	41	67	3	GO:1905360
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1 GNB2	4.19e-07	5	66	3	IPR016346
Domain	Gprotein_B	GNB4 GNB1 GNB2	4.97e-06	10	66	3	IPR001632
Domain	TPR_REGION	SPAG1 DNAH10 P3H1 GPSM2 ANAPC7 DNAJC3	2.54e-05	165	66	6	PS50293
Domain	TPR	SPAG1 DNAH10 P3H1 GPSM2 ANAPC7 DNAJC3	2.54e-05	165	66	6	PS50005
Domain	TPR_8	SPAG1 GPSM2 ANAPC7 DNAJC3	3.66e-05	53	66	4	PF13181
Domain	IPT	NFKB2 PLXND1 PLXNB3	1.16e-04	27	66	3	SM00429
Domain	-	WDR70 GNB4 WDR41 PLXND1 GNB1 GNB2 PLXNB3	1.70e-04	333	66	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR70 GNB4 WDR41 PLXND1 GNB1 GNB2 PLXNB3	1.76e-04	335	66	7	IPR015943
Domain	TPR-contain_dom	SPAG1 P3H1 GPSM2 ANAPC7 DNAJC3	1.88e-04	150	66	5	IPR013026
Domain	IPT	NFKB2 PLXND1 PLXNB3	1.94e-04	32	66	3	IPR002909
Domain	G-protein_beta_WD-40_rep	GNB4 WDR41 GNB1 GNB2	2.32e-04	85	66	4	IPR020472
Domain	WD40_repeat_CS	WDR70 GNB4 WDR41 GNB1 GNB2	2.85e-04	164	66	5	IPR019775
Domain	Plexin_cytopl	PLXND1 PLXNB3	4.36e-04	9	66	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNB3	4.36e-04	9	66	2	IPR013548
Domain	Plexin	PLXND1 PLXNB3	4.36e-04	9	66	2	IPR031148
Domain	Ig_E-set	MYCBP2 NFKB2 PLXND1 PLXNB3	5.02e-04	104	66	4	IPR014756
Domain	-	SPAG1 P3H1 GPSM2 ANAPC7 DNAJC3	8.23e-04	207	66	5	1.25.40.10
Domain	TPR	SPAG1 GPSM2 ANAPC7 DNAJC3	1.12e-03	129	66	4	SM00028
Domain	TPR_repeat	SPAG1 GPSM2 ANAPC7 DNAJC3	1.26e-03	133	66	4	IPR019734
Domain	TPR-like_helical_dom	SPAG1 P3H1 GPSM2 ANAPC7 DNAJC3	1.39e-03	233	66	5	IPR011990
Domain	Rib_L2_dom2	UHRF2 TP53BP1	1.81e-03	18	66	2	IPR014722
Domain	-	UHRF2 TP53BP1	1.81e-03	18	66	2	2.30.30.30
Domain	Znf_FYVE_PHD	KMT2A DIDO1 BSN UHRF2	1.82e-03	147	66	4	IPR011011
Domain	WD40	WDR70 GNB4 WDR41 GNB1 GNB2	2.21e-03	259	66	5	PF00400
Domain	-	MYCBP2 TRIM9 NFKB2 MXRA8 OBSCN PLXND1 EPHA10 PLXNB3	2.26e-03	663	66	8	2.60.40.10
Domain	PHD	KMT2A DIDO1 UHRF2	2.37e-03	75	66	3	PF00628
Domain	WD40	WDR70 GNB4 WDR41 GNB1 GNB2	2.57e-03	268	66	5	SM00320
Domain	WD40_repeat	WDR70 GNB4 WDR41 GNB1 GNB2	2.74e-03	272	66	5	IPR001680
Domain	Znf_PHD-finger	KMT2A DIDO1 UHRF2	2.75e-03	79	66	3	IPR019787
Domain	WD_REPEATS_1	WDR70 GNB4 WDR41 GNB1 GNB2	3.00e-03	278	66	5	PS00678
Domain	WD_REPEATS_2	WDR70 GNB4 WDR41 GNB1 GNB2	3.05e-03	279	66	5	PS50082
Domain	WD_REPEATS_REGION	WDR70 GNB4 WDR41 GNB1 GNB2	3.05e-03	279	66	5	PS50294
Domain	Ig-like_fold	MYCBP2 TRIM9 NFKB2 MXRA8 OBSCN PLXND1 EPHA10 PLXNB3	3.33e-03	706	66	8	IPR013783
Domain	PHD	KMT2A DIDO1 UHRF2	3.85e-03	89	66	3	SM00249
Domain	TPR_1	SPAG1 GPSM2 DNAJC3	3.98e-03	90	66	3	PF00515
Domain	TPR_1	SPAG1 GPSM2 DNAJC3	3.98e-03	90	66	3	IPR001440
Domain	WD40_repeat_dom	WDR70 GNB4 WDR41 GNB1 GNB2	3.98e-03	297	66	5	IPR017986
Domain	Znf_PHD	KMT2A DIDO1 UHRF2	4.10e-03	91	66	3	IPR001965
Domain	ZF_PHD_2	KMT2A DIDO1 UHRF2	4.63e-03	95	66	3	PS50016
Domain	ZF_PHD_1	KMT2A DIDO1 UHRF2	4.76e-03	96	66	3	PS01359
Domain	-	MYCBP2 TRIM9 KMT2A DIDO1 BSN UHRF2	5.02e-03	449	66	6	3.30.40.10
Domain	TIG	PLXND1 PLXNB3	5.35e-03	31	66	2	PF01833
Domain	Sema	PLXND1 PLXNB3	5.35e-03	31	66	2	SM00630
Domain	Semap_dom	PLXND1 PLXNB3	5.35e-03	31	66	2	IPR001627
Domain	Sema	PLXND1 PLXNB3	5.35e-03	31	66	2	PF01403
Domain	SEMA	PLXND1 PLXNB3	5.35e-03	31	66	2	PS51004
Domain	Znf_RING/FYVE/PHD	MYCBP2 TRIM9 KMT2A DIDO1 BSN UHRF2	5.58e-03	459	66	6	IPR013083
Domain	PSI	PLXND1 PLXNB3	5.70e-03	32	66	2	PF01437
Domain	Plexin_repeat	PLXND1 PLXNB3	5.70e-03	32	66	2	IPR002165
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2	4.93e-05	19	54	3	MM15021
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2	4.93e-05	19	54	3	M926
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ACACB FFAR1 GNB4 GNB1 GNB2	5.64e-05	108	54	5	M17034
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2	5.78e-05	20	54	3	MM15572
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2	5.78e-05	20	54	3	M27853
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2	6.73e-05	21	54	3	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2	6.73e-05	21	54	3	MM15159
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2	7.77e-05	22	54	3	MM15016
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2	7.77e-05	22	54	3	M841
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	FFAR1 GNB4 GNB1 GNB2	8.54e-05	61	54	4	MM15071
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2	8.91e-05	23	54	3	MM15033
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	8.91e-05	23	54	3	M47549
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2	1.02e-04	24	54	3	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2	1.02e-04	24	54	3	MM15088
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2	1.02e-04	24	54	3	M18308
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.02e-04	24	54	3	M47460
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2	1.02e-04	24	54	3	MM14794
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2	1.15e-04	25	54	3	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2	1.15e-04	25	54	3	M811
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2	1.15e-04	25	54	3	M14301
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2	1.30e-04	26	54	3	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.30e-04	26	54	3	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.30e-04	26	54	3	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.30e-04	26	54	3	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.30e-04	26	54	3	M47456
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.46e-04	27	54	3	M47454
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2	1.46e-04	27	54	3	MM15664
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2	1.63e-04	28	54	3	M10679
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	FFAR1 GNB4 GNB1 GNB2	1.63e-04	72	54	4	MM14631
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	1.81e-04	29	54	3	M47466
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2	2.00e-04	30	54	3	M18193
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1 GNB2	2.00e-04	30	54	3	MM14542
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	OBSCN GNB4 GNB1 GNB2	2.12e-04	77	54	4	MM15044
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2	2.21e-04	31	54	3	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.21e-04	31	54	3	M47554
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.21e-04	31	54	3	M47455
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.21e-04	31	54	3	M47459
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.21e-04	31	54	3	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.21e-04	31	54	3	M47541
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	FFAR1 GNB4 GNB1 GNB2	2.22e-04	78	54	4	M1921
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2	2.44e-04	32	54	3	M861
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2	2.44e-04	32	54	3	M14309
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2	2.44e-04	32	54	3	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2	2.44e-04	32	54	3	MM15143
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.44e-04	32	54	3	M47962
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2	2.44e-04	32	54	3	MM14983
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	OBSCN GNB4 GNB1 GNB2	2.45e-04	80	54	4	M800
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2	2.67e-04	33	54	3	MM15027
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2	2.67e-04	33	54	3	MM15020
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2	2.67e-04	33	54	3	MM15058
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.67e-04	33	54	3	M47550
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2	2.67e-04	33	54	3	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2	2.67e-04	33	54	3	M10322
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2	2.67e-04	33	54	3	M9379
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	GNB4 GNB1 GNB2	2.67e-04	33	54	3	M11575
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2	3.19e-04	35	54	3	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2	3.47e-04	36	54	3	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1 GNB2	4.08e-04	38	54	3	M27656
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1 GNB2	4.40e-04	39	54	3	MM15003
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2	4.75e-04	40	54	3	MM15115
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2	5.49e-04	42	54	3	M791
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	GNB4 GNB1 GNB2	5.88e-04	43	54	3	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2	5.88e-04	43	54	3	M933
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	5.88e-04	43	54	3	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	6.30e-04	44	54	3	MM15709
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2	6.73e-04	45	54	3	MM15040
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2	6.73e-04	45	54	3	M45008
Pathway	WP_INCLUSION_BODY_MYOSITIS	NFKB2 SIRT1	7.75e-04	11	54	2	M42545
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2	8.14e-04	48	54	3	M10775
Pathway	REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	FFAR1 GNB1	9.27e-04	12	54	2	MM15036
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2	1.03e-03	52	54	3	M920
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	FFAR1 GNB4 GNB1 GNB2 CCKBR	1.22e-03	210	54	5	MM15043
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	PSMD1 GNB4 GNB1 GNB2	1.25e-03	123	54	4	MM14988
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXND1 PLXNB3	1.27e-03	14	54	2	MM15047
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	FFAR1 GNB4 GNB1 GNB2 CCKBR	1.41e-03	217	54	5	M18437
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	1.56e-03	60	54	3	MM15708
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1 GNB2	1.56e-03	60	54	3	MM14964
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	1.56e-03	60	54	3	M976
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2	1.71e-03	62	54	3	M27321
Pathway	REACTOME_SIGNALING_BY_WNT	KREMEN2 PSMD1 GNB4 GNB1 GNB2	2.16e-03	239	54	5	MM14756
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	PSMD1 GNB4 GNB1 GNB2	2.34e-03	146	54	4	M27288
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXND1 PLXNB3	2.36e-03	19	54	2	M10959
Pathway	REACTOME_OPIOID_SIGNALLING	GNB4 GNB1 GNB2	2.53e-03	71	54	3	MM14491
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1 GNB2	2.53e-03	71	54	3	MM15590
Pathway	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1	FFAR1 GNB1	2.89e-03	21	54	2	M932
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1 GNB2	2.95e-03	75	54	3	M27874
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1 GNB2	3.07e-03	76	54	3	MM15051
Pathway	REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	FFAR1 GNB1	3.77e-03	24	54	2	M928
Pathway	REACTOME_SUMOYLATION	L3MBTL2 NFKB2 UHRF2 TP53BP1	3.95e-03	169	54	4	MM14919
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1 GNB2	4.34e-03	86	54	3	M916
Pubmed	Human transcription factor protein interaction networks.	CKB GTF3C1 ACACB L3MBTL2 DNAH10 TRIM9 NFKB2 KMT2A PSMD1 DIDO1 GNB4 NXF1 SIRT1 SNTB2 TP53BP1 SYMPK	9.41e-09	1429	67	16	35140242
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1 GNB2	2.73e-08	4	67	3	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1 GNB2	2.73e-08	4	67	3	12512701
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1 GNB2	1.36e-07	6	67	3	16371464
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1 GNB2	1.36e-07	6	67	3	16884933
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1 GNB2	3.80e-07	8	67	3	2328987
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CKB GTF3C1 MYCBP2 KMT2A PSMD1 DIDO1 NXF1 TP53BP1 SYMPK XPO7	4.82e-07	653	67	10	22586326
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1 GNB2	5.69e-07	9	67	3	10339615
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1 GNB2	8.12e-07	10	67	3	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1 GNB2	8.12e-07	10	67	3	9733924
Pubmed	The G protein subunit gene families.	GNB4 GNB1 GNB2	1.12e-06	11	67	3	10644457
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1 GNB2	1.12e-06	11	67	3	34932372
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1 GNB2	1.12e-06	11	67	3	25982117
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1 GNB2	1.48e-06	12	67	3	34342229
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1 GNB2	1.48e-06	12	67	3	20186915
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1 GNB2	1.48e-06	12	67	3	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1 GNB2	1.48e-06	12	67	3	8636150
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1 GNB2	3.06e-06	15	67	3	12486123
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CKB MYCBP2 P3H1 WDR70 PSMD1 GNB2 NXN ANAPC7 SIRT1 SNTB2 TP53BP1	3.25e-06	1005	67	11	19615732
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	3.66e-06	2	67	2	20525682
Pubmed	NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.	KMT2A SIRT1	3.66e-06	2	67	2	25751424
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1 GNB2	4.56e-06	17	67	3	19376773
Pubmed	Interaction network of human early embryonic transcription factors.	TBKBP1 ACACB L3MBTL2 KMT2A GNB2 UHRF2 SIRT1	5.20e-06	351	67	7	38297188
Pubmed	Positional cloning of the mouse saccharin preference (Sac) locus.	MXRA8 GNB1 ACAP3	1.03e-05	22	67	3	11555487
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	TMC1 NFKB2 PSMD1 GPANK1 KIFC2 SNTB2	1.05e-05	257	67	6	30945288
Pubmed	Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.	GNB1 GNB2	1.10e-05	3	67	2	25485910
Pubmed	KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair.	SIRT1 TP53BP1	1.10e-05	3	67	2	25905708
Pubmed	Faster lipid β-oxidation rate by acetyl-CoA carboxylase 2 inhibition alleviates high-glucose-induced insulin resistance via SIRT1/PGC-1α in human podocytes.	ACACB SIRT1	1.10e-05	3	67	2	33957017
Pubmed	Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues.	GNB4 GNB2	1.10e-05	3	67	2	10409705
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB2	1.10e-05	3	67	2	11913780
Pubmed	G protein beta gamma subunits. Simplified purification and properties of novel isoforms.	GNB1 GNB2	1.10e-05	3	67	2	8308009
Pubmed	KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.	GNB4 GNB1 GNB2	1.34e-05	24	67	3	23209302
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1 GNB2	2.16e-05	28	67	3	8858601
Pubmed	Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells.	KMT2A SYMPK	2.19e-05	4	67	2	23994619
Pubmed	G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.	GNB1 GNB2	2.19e-05	4	67	2	15955845
Pubmed	Cyclooxygenase-2-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor in a sirtuin-1-dependent-manner.	PTGIS SIRT1	2.19e-05	4	67	2	22865892
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB2	2.19e-05	4	67	2	19255495
Pubmed	A sperm component, HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit and activates extracellular signal-regulated kinases (ERK).	SPAG1 GNB1	2.19e-05	4	67	2	16368546
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	GTF3C1 L3MBTL2 WDR70 KMT2A DIDO1 UHRF2 ANAPC7 SIRT1	2.19e-05	608	67	8	36089195
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	GTF3C1 WDR70 KMT2A DIDO1 UHRF2 ANAPC7 NXF1 SIRT1 SYMPK XPO7	2.34e-05	1014	67	10	32416067
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	CKB ACACB MYCBP2 SYNGR2 PSMD1 DIDO1 GNB1 GNB2	2.64e-05	624	67	8	33729478
Pubmed	Glucagon and regulation of glucose metabolism.	GNB4 GNB1 GNB2	2.96e-05	31	67	3	12626323
Pubmed	Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.	GNB4 GNB1	3.64e-05	5	67	2	11294873
Pubmed	Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor.	GNB1 GNB2	3.64e-05	5	67	2	7649993
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	GTF3C1 L3MBTL2 NFKB2 WDR70 ANAPC7 TP53BP1 NOVA2 SYMPK XPO7	3.82e-05	857	67	9	25609649
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	CKB GTF3C1 L3MBTL2 KMT2A DIDO1 NXF1	4.97e-05	339	67	6	30415952
Pubmed	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.	GNB1 GNB2	5.46e-05	6	67	2	7665596
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	GNB1 GNB2	5.46e-05	6	67	2	9238069
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	GTF3C1 L3MBTL2 P3H1 GNB4 GNB1 GNB2 ANAPC7 NXF1 SIRT1 TP53BP1	6.98e-05	1155	67	10	20360068
Pubmed	Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.	NFKB2 KMT2A	7.63e-05	7	67	2	19219072
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1	7.63e-05	7	67	2	10570481
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	GTF3C1 L3MBTL2 ANAPC7 SYMPK	7.66e-05	116	67	4	21549307
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	GNB4 GNB1 GNB2	7.98e-05	43	67	3	26487511
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	SPAG1 GTF3C1 WDR70 PSMD1 ANAPC7 NXF1 SIRT1	8.81e-05	547	67	7	37267103
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCC1 DPY19L3 MAN2B2 GTF3C1 MYCBP2 P3H1 PLXND1 ITGA3 DNAJC3 SYMPK	9.63e-05	1201	67	10	35696571
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB2	1.02e-04	8	67	2	9789084
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB2	1.02e-04	8	67	2	24462769
Pubmed	Integral and associated lysosomal membrane proteins.	GNB4 WDR41 GNB1 GNB2	1.05e-04	126	67	4	17897319
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CKB TMC1 ACACB PSMD1 GNB1 DNAJC3 SNTB2	1.18e-04	573	67	7	28330616
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GTF3C1 MYCBP2 KMT2A PSMD1 DIDO1 SIRT1 TP53BP1 SYMPK	1.19e-04	774	67	8	15302935
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	GNB1 GNB2	1.30e-04	9	67	2	16498633
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	CKB ACACB MYCBP2 P3H1 WDR70 PSMD1 WDR41 DNAJC3 NXF1	1.31e-04	1007	67	9	34597346
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GTF3C1 ACACB L3MBTL2 MYCBP2 PSMD1 NXF1	1.56e-04	418	67	6	34709266
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	CKB MYCBP2 PSMD1 GNB1 GNB2	1.60e-04	264	67	5	32814769
Pubmed	Morphological diversity of single neurons in molecularly defined cell types.	GNB4 PLXND1	1.63e-04	10	67	2	34616072
Pubmed	SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.	ACACB SIRT1	1.63e-04	10	67	2	19720090
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	L3MBTL2 NFKB2 WDR70 GNB4 GNB1 GNB2 ANAPC7 SNTB2 ACAP3	1.64e-04	1038	67	9	26673895
Pubmed	Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.	GNB1 GNB2	1.99e-04	11	67	2	32332099
Pubmed	Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex.	GNB1 GNB2	1.99e-04	11	67	2	11685543
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	BSN TP53BP1	2.38e-04	12	67	2	28700933
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	ITGA3 BSN	2.38e-04	12	67	2	28386022
Pubmed	Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.	KMT2A PLXNB3	2.38e-04	12	67	2	12123608
Pubmed	Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.	GNB1 GNB2	2.38e-04	12	67	2	17110384
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXND1 PLXNB3	2.38e-04	12	67	2	21270798
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	GTF3C1 MYCBP2 KMT2A DIDO1 UHRF2 ANAPC7 NXF1 SIRT1 TP53BP1	2.58e-04	1103	67	9	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TBKBP1 MYCBP2 NFKB2 WDR70 OBSCN PLXND1 ITGA3 KIFC2 SYMPK	2.61e-04	1105	67	9	35748872
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXND1 PLXNB3	2.81e-04	13	67	2	10520995
Pubmed	The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.	GNB4 GNB1	2.81e-04	13	67	2	12782285
Pubmed	Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.	CKB GNB4 GNB1 GNB2	3.25e-04	169	67	4	17634366
Pubmed	Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C.	GNB1 GNB2	3.28e-04	14	67	2	19168127
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	MYCBP2 PSMD1 NXN ANAPC7	3.71e-04	175	67	4	25756610
Pubmed	Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation.	GNB1 GNB2	3.78e-04	15	67	2	23326349
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SPAG1 GTF3C1 ACACB KMT2A PSMD1 PADI6 GNB1 BSN ANAPC7 DNAJC3	4.19e-04	1442	67	10	35575683
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	GTF3C1 PSMD1 DIDO1 SIRT1 SNTB2 TP53BP1	4.20e-04	503	67	6	16964243
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	CKB ACACB L3MBTL2 TRIM9 WDR70 KMT2A DIDO1 TP53BP1	4.22e-04	934	67	8	33916271
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	ABCC1 ITGA3 ANAPC7 DNAJC3	4.39e-04	183	67	4	31932471
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	ABCC1 P3H1 PSMD1 GNB1 MTX1 DNAJC3 SYMPK XPO7	4.47e-04	942	67	8	31073040
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	CKB ABCC1 SPAG1 DPY19L3 P3H1 NFKB2 ANAPC7	4.65e-04	719	67	7	35337019
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PCDHB5 MXRA8 PSMD1 ITGA3 MTX1 TP53BP1 NOVA2 SYMPK XPO7	4.85e-04	1203	67	9	29180619
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXND1 PLXNB3	4.88e-04	17	67	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXND1 PLXNB3	4.88e-04	17	67	2	17626059
Pubmed	A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131.	TRPM5 GNB1	4.88e-04	17	67	2	24367558
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	GTF3C1 KMT2A DIDO1 TP53BP1 SYMPK	5.17e-04	341	67	5	32971831
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	GTF3C1 TRIM9 P3H1 OBSCN NXF1 PLXNB3 SYMPK	5.34e-04	736	67	7	29676528
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	CKB MAN2B2 PSMD1 TP53BP1 XPO7	5.37e-04	344	67	5	30333137
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TBKBP1 MAN2B2 GTF3C1 MYCBP2 WDR70 OBSCN PSMD1 NXN DNAJC3 XPO7	5.38e-04	1489	67	10	28611215
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	SPAG1 GNB1 GNB2 MTX1	5.79e-04	197	67	4	17500595
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	ABCC1 DIDO1 PTGIS GPANK1 TP53BP1	5.89e-04	351	67	5	20453000
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ABCC1 TBKBP1 MAN2B2 MYCBP2 TRIM9 GNB1 MTX1	6.16e-04	754	67	7	33060197
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CKB ACACB WDR70 DIDO1 SYMPK	6.35e-04	357	67	5	37059091
Interaction	EED interactions	CKB GTF3C1 ACACB L3MBTL2 MYCBP2 NFKB2 OBSCN PSMD1 DIDO1 GNB2 UHRF2 NXN NXF1 SIRT1 TP53BP1 SYMPK XPO7	2.75e-06	1445	66	17	int:EED
Interaction	GNGT2 interactions	GNB4 GNB1 GNB2	7.23e-06	12	66	3	int:GNGT2
Interaction	GNG11 interactions	GNB4 GNB1 GNB2	2.21e-05	17	66	3	int:GNG11
Interaction	RGS6 interactions	GNB4 GNB1 GNB2	2.64e-05	18	66	3	int:RGS6
Interaction	SIRT7 interactions	CKB GTF3C1 MYCBP2 KMT2A PSMD1 DIDO1 NXF1 SIRT1 TP53BP1 SYMPK XPO7	2.72e-05	744	66	11	int:SIRT7
Interaction	GNG7 interactions	GNB4 GNB1 GNB2	3.68e-05	20	66	3	int:GNG7
Interaction	RBBP7 interactions	ACACB L3MBTL2 MYCBP2 NFKB2 KMT2A PSMD1 SIRT1 SYMPK XPO7	3.89e-05	507	66	9	int:RBBP7
Interaction	GNG3 interactions	GNB4 GNB1 GNB2	6.46e-05	24	66	3	int:GNG3
Interaction	GNG4 interactions	GNB4 GNB1 GNB2	7.33e-05	25	66	3	int:GNG4
Interaction	GNGT1 interactions	GNB4 GNB1 GNB2	8.26e-05	26	66	3	int:GNGT1
GeneFamily	Plexins	PLXND1 PLXNB3	2.88e-04	9	52	2	683
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	SPAG1 GPSM2 ANAPC7 DNAJC3	3.32e-04	115	52	4	769
GeneFamily	WD repeat domain containing	WDR70 GNB4 WDR41 GNB1 GNB2	9.17e-04	262	52	5	362
GeneFamily	PHD finger proteins	KMT2A DIDO1 UHRF2	2.21e-03	90	52	3	88
GeneFamily	Tudor domain containing	UHRF2 TP53BP1	5.07e-03	37	52	2	780
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DPY19L3 CYP11A1 KREMEN2 OBSCN CCKBR	4.73e-06	163	67	5	218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CKB FFAR1 BSN EPHA10 CCDC33	6.32e-06	173	67	5	f31e738c2b3b319fb40b0b16b2393a51c9a8999c
ToppCell	(05)_Ciliated-(4)_1wkpi\|(05)_Ciliated / shred by cell type and Timepoint	DNAH10 EXD1 ANAPC7 EPHA10 PLXNB3	7.66e-06	180	67	5	85fc9b164147b28545e2397d32302eea03ef6346
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYCBP2 KMT2A BSN KIFC2 EPHA10	9.95e-06	190	67	5	416de85d8841dac883faa6f5339b2fb461a09e82
Drug	Mometasone furoate [83919-23-7]; Down 200; 7.6uM; HL60; HG-U133A	CKB ABCC1 GTF3C1 TRIM9 NFKB2 DIDO1 TP53BP1	1.83e-06	197	67	7	1746_DN
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	TBKBP1 ACACB DNAH10 TP53BP1 NOVA2	1.48e-04	224	66	5	EFO_0004574, EFO_0008317
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	TBKBP1 ACACB DNAH10 TP53BP1 NOVA2	1.51e-04	225	66	5	EFO_0008317, EFO_0010351
Disease	Heart Diseases	ABCC1 BSN SIRT1	1.51e-04	46	66	3	C0018799
Disease	Paroxysmal atrial fibrillation	DNAH10 GNB4 SIRT1 XPO7	4.20e-04	156	66	4	C0235480
Disease	familial atrial fibrillation	DNAH10 GNB4 SIRT1 XPO7	4.20e-04	156	66	4	C3468561
Disease	Persistent atrial fibrillation	DNAH10 GNB4 SIRT1 XPO7	4.20e-04	156	66	4	C2585653
Disease	Atrial Fibrillation	DNAH10 GNB4 SIRT1 XPO7	4.62e-04	160	66	4	C0004238
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	TBKBP1 ACACB DNAH10 TP53BP1	5.31e-04	166	66	4	EFO_0004530, EFO_0004611
Disease	Tourette syndrome, schizophrenia	DNAH10 CACNA1I	7.37e-04	18	66	2	EFO_0004895, MONDO_0005090
Disease	obesity (implicated_via_orthology)	DNAH10 PLXND1 SIRT1 PLXNB3	1.39e-03	215	66	4	DOID:9970 (implicated_via_orthology)
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	TBKBP1 ACACB DNAH10 TP53BP1	1.39e-03	215	66	4	EFO_0008317, EFO_0008591
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	TBKBP1 ACACB DNAH10 TP53BP1	1.51e-03	220	66	4	EFO_0004529, EFO_0008317
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	TBKBP1 ACACB DNAH10 TP53BP1	1.75e-03	229	66	4	EFO_0004639, EFO_0008317
Disease	apolipoprotein A 1 measurement, apolipoprotein B measurement	TBKBP1 DNAH10 NOVA2	1.80e-03	107	66	3	EFO_0004614, EFO_0004615
Disease	fatty liver disease (implicated_via_orthology)	ACACB SIRT1	2.20e-03	31	66	2	DOID:9452 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GFNEAGRYALRLSAE	CCDC33	36	Q8N5R6
ELDSLFSYFDAGAAG	ACAP3	586	Q96P50
KFGLGATRDFDANLY	DPY19L3	381	Q6ZPD9
YLGLRFDGDSDSDSQ	CCKBR	246	P32239
ALNAFGSGDYTAAIA	DNAJC3	161	Q13217
ESLRAFDSDGDGRYS	EFCAB14	471	O75071
FDSDGDGRYSFLELR	EFCAB14	476	O75071
DNFAYLAASADLRGG	GALNT16	246	Q8N428
ARDLDAGAYGSVAYA	PCDHB5	266	Q9Y5E4
DLLFAEGTAAYARGD	P3H1	36	Q32P28
LADQYGNAVSLFGRD	ACACB	506	O00763
GSLADLYFRAGDNKN	ANAPC7	241	Q9UJX3
RGGGLAAADDFLYLE	OVOS1	36	Q6IE37
GYGDALLFDELRADQ	PADI6	521	Q6TGC4
ENYANGSLGFLLADA	LIPN	96	Q5VXI9
GDKAAERRAYSNLGN	GPSM2	236	P81274
DGAAARAFYEALIGD	GPANK1	36	O95872
ALSSLDGDLAGRYYA	CKB	161	P12277
DDDLELFGGYDSFRS	L3MBTL2	21	Q969R5
DGYLNTYREGSADRL	EXD1	276	Q8NHP7
RGDAVGFQEASLAQY	BSN	2076	Q9UPA5
LGSNLGRAFADVQYA	PLXNB3	856	Q9ULL4
NFALDGAAGTVYLAA	PLXND1	61	Q9Y4D7
YFGSAIALADLNNDG	ITGA3	306	P26006
AIYDSGDRQGLLDAY	NXF1	396	Q9UBU9
AQGFALTYRGLQDAA	KREMEN2	316	Q8NCW0
SGRLLLAGYDDFNCN	GNB2	281	P62879
SGRLLLAGYDDFNCN	GNB4	281	Q9HAV0
YTNGFGALRDGLEFA	OTUD7A	851	Q8TE49
KDSFAAAGYGSLEAV	EPHA10	951	Q5JZY3
AAAANLLASYAGEAG	NOVA2	321	Q9UNW9
GAADADIGANALLTY	PCDHA1	156	Q9Y5I3
AAGARFRLAQDGDLY	OBSCN	51	Q5VST9
FLAALSAGRYLGAAF	FFAR1	96	O14842
SGRLLLAGYDDFNCN	GNB1	281	P62873
YDFGAGRQDLNASGL	CACNA1I	301	Q9P0X4
LVEGFQAEGDANRSY	CACNA1I	861	Q9P0X4
ASADFREGKGHEYRN	DIDO1	2066	Q9BTC0
SGNYSGDISDDLFRF	CYP11A1	191	P05108
AGFNAHLGSRIDYDL	MAN2B2	166	Q9Y2E5
DDSANDAGRLLYIGQ	KMT2A	1881	Q03164
YDNIASLRFNDGDSG	DNAH10	1596	Q8IVF4
IFYSLFRRDGGAAAA	KIFC2	11	Q96AC6
YDFFQLERAAAEGAS	KIF28P	496	B7ZC32
DYDLSARQGADTLAF	MTX1	231	Q13505
SYQELLARDGAFAEF	ABCC1	851	P33527
AAGSDLAFNLEGYIF	SLC35D2	161	Q76EJ3
ASLAAFYGRLRGDAA	NXN	51	Q6DKJ4
GYALDFGKDAASFLT	PTGIS	41	Q16647
LGAFEESLNYALGAG	PSMD1	71	Q99460
AAAAIGYRDNLLFGD	SIRT1	136	Q96EB6
GEYINQIAASRDDGF	MYCBP2	466	O75592
RFFSANEGLDDYLEA	TMEM151A	241	Q8N4L1
RAEEASAANFGVLYD	TMC1	231	Q8TDI8
SAANFGVLYDFNGLA	TMC1	236	Q8TDI8
RSNDGAYSLVLAGGF	UHRF2	481	Q96PU4
DNGADVADFLTYGRL	TRPM5	401	Q9NZQ8
EALAADFFNRTELGY	SLFN12L	196	Q6IEE8
FSYDGNVLASRGGDD	WDR70	386	Q9NW82
FRSGQFAEAAGKYSA	SPAG1	456	Q07617
RAGAGYILEDFNEAQ	TP53BP1	1781	Q12888
YGAAKAGGSFDLRRF	SYNGR2	6	O43760
EYNAYLAAGASGSLD	SYMPK	626	Q92797
RAAGSGVSDYDYLDL	TRIM9	51	Q9C026
GVFRLYGDDALDNAL	XPO7	851	Q9UIA9
AAGLDSSFYGHLKRN	GTF3C1	1116	Q12789
SADDGIRNLYLDFGG	SNTB2	491	Q13425
FQGRRSYSELAEGAA	TBKBP1	456	A7MCY6
QLDDYRFASAGDDGI	WDR41	51	Q9HAD4
GRLELSASAFDDGNF	MXRA8	106	Q9BRK3
FGLAQRSARALLDYG	NFKB2	451	Q00653