Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cell adhesion mediator activity	NRCAM SIRPB1 PDLIM5 PDLIM1 MYPN VCAM1	1.90e-05	76	145	6	GO:0098631
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	NRCAM SIRPB1 PDLIM5 PDLIM1 MYPN	8.08e-05	61	145	5	GO:0098632
GeneOntologyMolecularFunction	cell adhesion molecule binding	NRCAM DBNL LAMA5 SIRPB1 PDLIM5 THBS4 PTPRB TENM3 PDLIM1 PTPRM MYPN SNX9 DHX29 VCAM1	1.21e-04	599	145	14	GO:0050839
GeneOntologyMolecularFunction	muscle alpha-actinin binding	PDLIM5 PDLIM1 MYPN	1.60e-04	15	145	3	GO:0051371
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRB PTPRM PTPRR	2.37e-04	17	145	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRB PTPRM PTPRR	2.37e-04	17	145	3	GO:0019198
GeneOntologyMolecularFunction	structural constituent of egg coat	ZP3 POMZP3	5.16e-04	5	145	2	GO:0035804
GeneOntologyMolecularFunction	acrosin binding	ZP3 POMZP3	7.71e-04	6	145	2	GO:0032190
GeneOntologyMolecularFunction	cytoskeletal protein binding	NRCAM MAPT DBNL CAMSAP3 CEACAM6 TPGS1 KIF24 PDLIM5 GSN SETD2 TTBK1 PDLIM1 GLI1 SIPA1L1 MYPN UNC5C KIF3C MYBPC3	1.04e-03	1099	145	18	GO:0008092
GeneOntologyMolecularFunction	IgG receptor activity	FCGR2C FCGR2A	1.07e-03	7	145	2	GO:0019770
GeneOntologyBiologicalProcess	inflammatory response to antigenic stimulus	ZP3 RAB44 AK7 RASGRP1 FCGR2C POMZP3 FCGR2A	8.28e-06	103	145	7	GO:0002437
GeneOntologyBiologicalProcess	cell recognition	NRCAM SIRPB1 ZP3 OPCML HAVCR2 POMZP3 FCGR2A NTM MYPN	1.14e-05	198	145	9	GO:0008037
GeneOntologyBiologicalProcess	in utero embryonic development	CAMSAP3 GATA6 SALL4 SKIL ZP3 SETD2 POMZP3 KMT2D TRIM28 ANKRD11 C5 EPN1 EPAS1 ELL VCAM1	2.05e-05	596	145	15	GO:0001701
GeneOntologyBiologicalProcess	cell-cell adhesion	ZNF609 NRCAM PCDHGA3 CAMSAP3 CEACAM6 SIRPB1 ZP3 PDLIM5 PLEKHG4B HAVCR2 RASGRP1 THBS4 POMZP3 TENM3 PDLIM1 PTPRM PTPRR MYPN PKHD1 IL4I1 VCAM1	2.12e-05	1077	145	21	GO:0098609
GeneOntologyBiologicalProcess	hypersensitivity	ZP3 FCGR2C POMZP3 FCGR2A	2.64e-05	25	145	4	GO:0002524
GeneOntologyBiologicalProcess	positive regulation of type IV hypersensitivity	ZP3 POMZP3	4.91e-05	2	145	2	GO:0001809
GeneOntologyBiologicalProcess	leukocyte activation	MPL IL11RA VPREB1 ERCC1 ZNF609 MAPT PATZ1 CEACAM6 SIRPB1 HMOX1 ZP3 RAB44 GSN HAVCR2 RASGRP1 POMZP3 TTBK1 FCGR2A FYB1 IL4I1 VCAM1	8.53e-05	1186	145	21	GO:0045321
GeneOntologyBiologicalProcess	positive regulation of hypersensitivity	ZP3 POMZP3 FCGR2A	1.46e-04	15	145	3	GO:0002885
GeneOntologyBiologicalProcess	positive regulation of acrosomal vesicle exocytosis	ZP3 POMZP3	1.47e-04	3	145	2	GO:2000368
GeneOntologyBiologicalProcess	positive regulation of antral ovarian follicle growth	ZP3 POMZP3	1.47e-04	3	145	2	GO:2000388
GeneOntologyBiologicalProcess	regulation of antral ovarian follicle growth	ZP3 POMZP3	1.47e-04	3	145	2	GO:2000387
GeneOntologyBiologicalProcess	egg coat formation	ZP3 POMZP3	1.47e-04	3	145	2	GO:0035803
GeneOntologyBiologicalProcess	cell activation	MPL IL11RA VPREB1 ERCC1 ZNF609 MAPT PATZ1 CEACAM6 SIRPB1 HMOX1 F2RL2 ZP3 RAB44 GSN HAVCR2 RASGRP1 POMZP3 TTBK1 FCGR2A FYB1 IL4I1 VCAM1	2.01e-04	1356	145	22	GO:0001775
GeneOntologyBiologicalProcess	acute inflammatory response to antigenic stimulus	ZP3 FCGR2C POMZP3 FCGR2A	2.13e-04	42	145	4	GO:0002438
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to antigenic stimulus	ZP3 POMZP3 FCGR2A	2.15e-04	17	145	3	GO:0002866
GeneOntologyBiologicalProcess	leukocyte mediated immunity	MPL ERCC1 CEACAM6 HMOX1 ZP3 RAB44 HAVCR2 RASGRP1 FCGR2C POMZP3 FCGR2A C5 IL4I1	2.19e-04	576	145	13	GO:0002443
GeneOntologyBiologicalProcess	regulation of chemokine production	MPL SIRPB1 HMOX1 HAVCR2 C5 SUZ12	2.57e-04	125	145	6	GO:0032642
GeneOntologyBiologicalProcess	regulation of homophilic cell adhesion	CEACAM6 TENM3 PTPRR	2.57e-04	18	145	3	GO:1903385
GeneOntologyBiologicalProcess	regulation of cytokine production	MPL PATZ1 PELI3 PER1 GATA6 CEACAM6 SIRPB1 HMOX1 ZP3 HAVCR2 RASGRP1 FCGR2C SETD2 POMZP3 FCGR2A UBR5 C5 SUZ12	2.64e-04	1010	145	18	GO:0001817
GeneOntologyBiologicalProcess	lipid tube assembly	PCDHGA3 SNX9	2.92e-04	4	145	2	GO:0060988
GeneOntologyBiologicalProcess	regulation of acrosomal vesicle exocytosis	ZP3 POMZP3	2.92e-04	4	145	2	GO:2000367
GeneOntologyBiologicalProcess	regulation of hypersensitivity	ZP3 POMZP3 FCGR2A	3.04e-04	19	145	3	GO:0002883
GeneOntologyBiologicalProcess	lymphocyte mediated immunity	MPL ERCC1 CEACAM6 ZP3 HAVCR2 RASGRP1 FCGR2C POMZP3 FCGR2A C5 IL4I1	3.41e-04	449	145	11	GO:0002449
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	NRCAM PCDHGA3 CEACAM6 TENM3 PTPRM PTPRR MYPN	3.63e-04	187	145	7	GO:0007156
GeneOntologyBiologicalProcess	chemokine production	MPL SIRPB1 HMOX1 HAVCR2 C5 SUZ12	3.89e-04	135	145	6	GO:0032602
GeneOntologyBiologicalProcess	negative regulation of response to tumor cell	CEACAM6 HAVCR2 IL4I1	4.12e-04	21	145	3	GO:0002835
GeneOntologyBiologicalProcess	negative regulation of immune response to tumor cell	CEACAM6 HAVCR2 IL4I1	4.12e-04	21	145	3	GO:0002838
GeneOntologyBiologicalProcess	embryo development	ERCC1 CAMSAP3 GATA6 LAMA5 SALL4 GTF2IRD1 SKIL ZP3 SETD2 POMZP3 KMT2D LRIG1 TRIM28 GLI1 ANKRD11 C5 C2orf49 EPN1 EPAS1 ELL VCAM1 TP53BP2	4.48e-04	1437	145	22	GO:0009790
GeneOntologyBiologicalProcess	regulation of type IV hypersensitivity	ZP3 POMZP3	4.84e-04	5	145	2	GO:0001807
GeneOntologyBiologicalProcess	negative regulation of binding of sperm to zona pellucida	ZP3 POMZP3	4.84e-04	5	145	2	GO:2000360
Domain	IG	IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 LRIG1 FCGR2A PTPRM NTM MYPN UNC5C KIR2DL5A VCAM1 MYBPC3	2.74e-08	421	144	17	SM00409
Domain	Ig_sub	IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 LRIG1 FCGR2A PTPRM NTM MYPN UNC5C KIR2DL5A VCAM1 MYBPC3	2.74e-08	421	144	17	IPR003599
Domain	-	MPL IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 PTPRB LRIG1 FCGR2A PTPRM NTM MYPN UNC5C PKHD1 KIR2DL5A VCAM1 MYBPC3	1.86e-07	663	144	20	2.60.40.10
Domain	IG_LIKE	IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 LRIG1 FCGR2A PTPRM NTM MYPN UNC5C KIR2DL5A VCAM1 MYBPC3	2.49e-07	491	144	17	PS50835
Domain	Ig-like_dom	IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 LRIG1 FCGR2A PTPRM NTM MYPN UNC5C KIR2DL5A VCAM1 MYBPC3	3.49e-07	503	144	17	IPR007110
Domain	Ig-like_fold	MPL IL11RA VPREB1 NRCAM CEACAM6 SIRPB1 FCRLA OPCML HAVCR2 PTPRB LRIG1 FCGR2A PTPRM NTM MYPN UNC5C PKHD1 KIR2DL5A VCAM1 MYBPC3	5.04e-07	706	144	20	IPR013783
Domain	IGc2	NRCAM CEACAM6 OPCML LRIG1 FCGR2A NTM MYPN UNC5C VCAM1 MYBPC3	1.45e-05	235	144	10	SM00408
Domain	Ig_sub2	NRCAM CEACAM6 OPCML LRIG1 FCGR2A NTM MYPN UNC5C VCAM1 MYBPC3	1.45e-05	235	144	10	IPR003598
Domain	Ig_I-set	NRCAM CEACAM6 OPCML LRIG1 NTM MYPN UNC5C VCAM1 MYBPC3	1.69e-05	190	144	9	IPR013098
Domain	I-set	NRCAM CEACAM6 OPCML LRIG1 NTM MYPN UNC5C VCAM1 MYBPC3	1.69e-05	190	144	9	PF07679
Domain	ig	IL11RA NRCAM CEACAM6 OPCML FCGR2A PTPRM NTM KIR2DL5A VCAM1	1.69e-05	190	144	9	PF00047
Domain	Immunoglobulin	IL11RA NRCAM CEACAM6 OPCML FCGR2A PTPRM NTM KIR2DL5A VCAM1	1.69e-05	190	144	9	IPR013151
Domain	SPAR_C	SIPA1L1 SIPA1L2	1.76e-04	3	144	2	PF11881
Domain	SIPA1L_C	SIPA1L1 SIPA1L2	1.76e-04	3	144	2	IPR021818
Domain	PolyA	UBR5 PABPC3	5.81e-04	5	144	2	SM00517
Domain	-	UBR5 PABPC3	5.81e-04	5	144	2	1.10.1900.10
Domain	PABP	UBR5 PABPC3	5.81e-04	5	144	2	PF00658
Domain	PABC	UBR5 PABPC3	5.81e-04	5	144	2	PS51309
Domain	PABP_HYD	UBR5 PABPC3	5.81e-04	5	144	2	IPR002004
Domain	DUF4749	PDLIM5 PDLIM1	8.68e-04	6	144	2	PF15936
Domain	DUF4749	PDLIM5 PDLIM1	8.68e-04	6	144	2	IPR031847
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NELFE EP400 DBNL ANKHD1 PDLIM5 TAB3 SETD2 KMT2D GTF3C2 PDLIM1 TRIM28 SEC16A PEAK1 SNX9 TP53BP2	1.79e-08	549	150	15	38280479
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	NELFE PTTG1 XRN2 RRP1B TROAP DBNL CAMSAP3 LIG1 GTF3C2 TRIM28 MYPN SEC16A TRIM47 DHX29	4.36e-08	503	150	14	16964243
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CPEB2 NRCAM MAPT DBNL CAMSAP3 TPGS1 OPCML PDLIM5 GSN LRCH3 SACM1L MLXIPL THBS4 LRIG1 TRIM28 NTM PABPC3 SIPA1L1 SEC16A PEAK1 SIPA1L2 DHX29 TP53BP2	5.55e-08	1431	150	23	37142655
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	XRN2 ERCC1 EP400 RRP1B LRCH3 SETD2 NUP155 GTF3C2 UBR5 TRIM28 SEC16A SNX9 DHX29	6.80e-08	440	150	13	34244565
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TAB3 C6orf132 NUP155 MEIOC SEC16A TACC1 PEAK1 SIPA1L2 TP53BP2 PDZD4	2.38e-07	263	150	10	34702444
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NELFE PTTG1 XRN2 EP400 MAPT CAMSAP3 GTF2IRD1 REXO1 LIG1 SETD2 KMT2D TRIM28 SIPA1L1 SEC16A SUZ12 DHX29	2.67e-07	774	150	16	15302935
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	TROAP PDLIM5 LRCH3 NUP155 SIPA1L1 SEC16A SIPA1L2	1.07e-06	122	150	7	30773093
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NELFE MAPT PATZ1 DBNL CAMSAP3 FRYL TAB3 C6orf132 MLXIPL SYDE2 SIPA1L1 SEC16A ANKRD11 PEAK1 SIPA1L2 TP53BP2	1.08e-06	861	150	16	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EP400 THAP8 PER1 LAMA5 FRYL GTF2IRD1 ANKHD1 REXO1 C6orf132 KMT2D TRIM28 GLI1 SEC16A ANKRD11 SIPA1L2 ANKRD33B ELL ABCC10	1.46e-06	1105	150	18	35748872
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	XRN2 ZNF609 PHF20 EP400 RRP1B RPN2 PATZ1 GATA6 GTF2IRD1 SKIL FKBP11 DHX8 MLXIPL SETD2 KMT2D GTF3C2 TRIM28 ANKRD11 SUZ12	3.33e-06	1294	150	19	30804502
Pubmed	Integration of a c-myc transgene results in disruption of the mouse Gtf2ird1 gene, the homologue of the human GTF2IRD1 gene hemizygously deleted in Williams-Beuren syndrome.	GTF2IRD1 ZP3 POMZP3	4.33e-06	8	150	3	11352562
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF609 EP400 MAPT PATZ1 PER1 SIRPB1 ANKHD1 SKIL ZC3H3 SETD2 DIMT1 UBR5 TRIM28 SIPA1L1 SEC16A SUZ12 SIPA1L2	7.06e-06	1116	150	17	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRCAM EP400 SACM1L TENM3 UBR5 SIPA1L1 SEC16A SUZ12 SIPA1L2 ST18	1.18e-05	407	150	10	12693553
Pubmed	Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.	LAMA5 LRIG1 GLI1 UNC5C	1.23e-05	33	150	4	18480165
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ZNF609 RRP1B RPN2 CAMSAP3 SHOC2 CDCA8 TAB3 KMT2D PTPRB ZFYVE9 NUP155 PTPRM PTPRR SEC16A PEAK1 TP53BP2	1.31e-05	1049	150	16	27880917
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	GTF2IRD1 ZP3 MLXIPL POMZP3	1.57e-05	35	150	4	11013070
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TPGS1 LRCH3 ZFYVE9 NUP155 TENM3 PTPRM UNC5C SEC16A PEAK1 SIPA1L2	1.58e-05	421	150	10	36976175
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NELFE XRN2 ZNF609 EP400 RRP1B CDCA8 TASOR2 NCBP3 SETD2 TRIM28 PABPC3 SEC16A ANKRD11 C2orf49 ELL	1.75e-05	954	150	15	36373674
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	TPGS1 LRCH3 PARP4 ZFYVE9 SIPA1L1 SEC16A	1.79e-05	125	150	6	29467281
Pubmed	Identification of a region of mouse zona pellucida glycoprotein mZP3 that possesses sperm receptor activity.	ZP3 POMZP3	1.85e-05	2	150	2	1330788
Pubmed	Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida.	ZP3 POMZP3	1.85e-05	2	150	2	3378665
Pubmed	Oocyte-specific gene expression: molecular characterization of a cDNA coding for ZP-3, the sperm receptor of the mouse zona pellucida.	ZP3 POMZP3	1.85e-05	2	150	2	3012564
Pubmed	Human ZP3 restores fertility in Zp3 null mice without affecting order-specific sperm binding.	ZP3 POMZP3	1.85e-05	2	150	2	9609824
Pubmed	Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.	OPCML NTM	1.85e-05	2	150	2	24616287
Pubmed	The microenvironment for erythropoiesis is regulated by HIF-2alpha through VCAM-1 in endothelial cells.	EPAS1 VCAM1	1.85e-05	2	150	2	18451309
Pubmed	Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.	KIR2DL5B KIR2DL5A	1.85e-05	2	150	2	12185535
Pubmed	Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction.	ZP3 POMZP3	1.85e-05	2	150	2	17258189
Pubmed	Innate antiviral resistance influences the efficacy of a recombinant murine cytomegalovirus immunocontraceptive vaccine.	ZP3 POMZP3	1.85e-05	2	150	2	17007971
Pubmed	Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.	KIR2DL5B KIR2DL5A	1.85e-05	2	150	2	11086080
Pubmed	Mapping the mouse ZP3 combining site for sperm by exon swapping and site-directed mutagenesis.	ZP3 POMZP3	1.85e-05	2	150	2	7816829
Pubmed	Immunoglobulin to zona pellucida 3 mediates ovarian damage and infertility after contraceptive vaccination in mice.	ZP3 POMZP3	1.85e-05	2	150	2	20382503
Pubmed	Ovarian development in mice bearing homozygous or heterozygous null mutations in zona pellucida glycoprotein gene mZP3.	ZP3 POMZP3	1.85e-05	2	150	2	9476659
Pubmed	Genomic organization of a sex specific gene: the primary sperm receptor of the mouse zona pellucida.	ZP3 POMZP3	1.85e-05	2	150	2	2535821
Pubmed	Oligosaccharide constructs with defined structures that inhibit binding of mouse sperm to unfertilized eggs in vitro.	ZP3 POMZP3	1.85e-05	2	150	2	7718569
Pubmed	cis-acting DNA elements involved in oocyte-specific expression of mouse sperm receptor gene mZP3 are located close to the gene's transcription start site.	ZP3 POMZP3	1.85e-05	2	150	2	8305213
Pubmed	Altered target organ. A mechanism of postrecovery resistance to murine autoimmune oophoritis.	ZP3 POMZP3	1.85e-05	2	150	2	7561067
Pubmed	A mouse oocyte-specific protein that binds to a region of mZP3 promoter responsible for oocyte-specific mZP3 gene expression.	ZP3 POMZP3	1.85e-05	2	150	2	1729594
Pubmed	Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats.	ZP3 POMZP3	1.85e-05	2	150	2	19052627
Pubmed	Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.	DBNL FYB1	1.85e-05	2	150	2	15848169
Pubmed	Selective activation of Gi1 and Gi2 in mouse sperm by the zona pellucida, the egg's extracellular matrix.	ZP3 POMZP3	1.85e-05	2	150	2	8175755
Pubmed	Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress.	THBS4 KMT2D	1.85e-05	2	150	2	38876442
Pubmed	FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.	FCRLA FCGR2C	1.85e-05	2	150	2	27015273
Pubmed	Secretion of zona pellucida glycoprotein mZP2 by growing oocytes from mZP3(+/+) and mZP3(-/-) mice.	ZP3 POMZP3	1.85e-05	2	150	2	10440843
Pubmed	Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile.	ZP3 POMZP3	1.85e-05	2	150	2	8787763
Pubmed	Lewis X-containing glycans are specific and potent competitive inhibitors of the binding of ZP3 to complementary sites on capacitated, acrosome-intact mouse sperm.	ZP3 POMZP3	1.85e-05	2	150	2	15128590
Pubmed	Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.	KIR2DL5B KIR2DL5A	1.85e-05	2	150	2	17215859
Pubmed	Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs.	ZP3 POMZP3	1.85e-05	2	150	2	14645511
Pubmed	A duplicated motif controls assembly of zona pellucida domain proteins.	ZP3 POMZP3	1.85e-05	2	150	2	15079052
Pubmed	Recombinant mouse ZP3 inhibits sperm binding and induces the acrosome reaction.	ZP3 POMZP3	1.85e-05	2	150	2	1577197
Pubmed	C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease.	FCGR2A C5	1.85e-05	2	150	2	12488432
Pubmed	Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules.	OPCML NTM	1.85e-05	2	150	2	7891157
Pubmed	Predictive and prognostic values of tau and ERCC1 in advanced breast cancer patients treated with paclitaxel and cisplatin.	ERCC1 MAPT	1.85e-05	2	150	2	20085902
Pubmed	Identification and spatial distribution of the mRNA encoding an egg envelope component of the Cyprinid zebrafish, Danio rerio, homologous to the mammalian ZP3 (ZPC).	ZP3 POMZP3	1.85e-05	2	150	2	10603086
Pubmed	Targeted disruption of the mZP3 gene results in production of eggs lacking a zona pellucida and infertility in female mice.	ZP3 POMZP3	1.85e-05	2	150	2	8643592
Pubmed	Genetic factors contributing to autism spectrum disorder in Williams-Beuren syndrome.	MLXIPL UBR5	1.85e-05	2	150	2	31413120
Pubmed	Nucleotide sequence of cDNA encoding bonnet monkey (Macaca radiata) zona pellucida glycoprotein-ZP3.	ZP3 POMZP3	1.85e-05	2	150	2	8848588
Pubmed	POM-ZP3, a bipartite transcript derived from human ZP3 and a POM121 homologue.	ZP3 POMZP3	1.85e-05	2	150	2	7789967
Pubmed	Polypeptide backbone derived from carboxyl terminal of mouse ZP3 inhibits sperm-zona binding.	ZP3 POMZP3	1.85e-05	2	150	2	17290430
Pubmed	Polypeptide encoded by mouse ZP3 exon-7 is necessary and sufficient for binding of mouse sperm in vitro.	ZP3 POMZP3	1.85e-05	2	150	2	16245311
Pubmed	Antibodies to two ZP3 B cell epitopes affect zona pellucida assembly.	ZP3 POMZP3	1.85e-05	2	150	2	18420282
Pubmed	Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells.	ZP3 POMZP3	1.85e-05	2	150	2	15379548
Pubmed	ZP3 is Required for Germinal Vesicle Breakdown in Mouse Oocyte Meiosis.	ZP3 POMZP3	1.85e-05	2	150	2	28145526
Pubmed	Heme Oxygenase 1 Induces Tau Oligomer Formation and Synapse Aberrations in Hippocampal Neurons.	MAPT HMOX1	1.85e-05	2	150	2	30040734
Pubmed	Oocyte proteomics: localisation of mouse zona pellucida protein 3 to the plasma membrane of ovulated mouse eggs.	ZP3 POMZP3	1.85e-05	2	150	2	14972104
Pubmed	Synergistic effect of heme oxygenase-1 and tau genetic variants on Alzheimer's disease risk.	MAPT HMOX1	1.85e-05	2	150	2	18841019
Pubmed	Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.	TRIM28 SUZ12	1.85e-05	2	150	2	17542650
Pubmed	Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning.	ZP3 POMZP3	1.85e-05	2	150	2	2842770
Pubmed	Biosynthesis of the sperm receptor during oogenesis in the mouse.	ZP3 POMZP3	1.85e-05	2	150	2	11892795
Pubmed	Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α.	HMOX1 VCAM1	1.85e-05	2	150	2	32121588
Pubmed	Localization of ZP3 mRNA in mouse ovary by non-radioactive in situ hybridization with digoxigenin-labelled cDNA.	ZP3 POMZP3	1.85e-05	2	150	2	7873981
Pubmed	Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3--the mouse sperm receptor.	ZP3 POMZP3	1.85e-05	2	150	2	2541416
Pubmed	Conversion of Ser to Thr residues at the sperm combining-site of mZP3 does not affect sperm receptor activity.	ZP3 POMZP3	1.85e-05	2	150	2	12589785
Pubmed	Murine sperm-zona binding, a fucosyl residue is required for a high affinity sperm-binding ligand. A second site on sperm binds a nonfucosylated, beta-galactosyl-capped oligosaccharide.	ZP3 POMZP3	1.85e-05	2	150	2	9442021
Pubmed	CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD.	CEACAM6 HMOX1	1.85e-05	2	150	2	37219322
Pubmed	Oocyte-specific expression and developmental regulation of ZP3, the sperm receptor of the mouse zona pellucida.	ZP3 POMZP3	1.85e-05	2	150	2	2884155
Pubmed	Novel expression of zona pellucida 3 protein in normal testis; potential functional implications.	ZP3 POMZP3	1.85e-05	2	150	2	34736966
Pubmed	Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans.	ZP3 POMZP3	1.85e-05	2	150	2	14673092
Pubmed	Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.	MAPT TTBK1	1.85e-05	2	150	2	20354135
Pubmed	Characterization of mouse ZP3-derived glycopeptide, gp55, that exhibits sperm receptor and acrosome reaction-inducing activity in vitro.	ZP3 POMZP3	1.85e-05	2	150	2	8672430
Pubmed	Contraception in mice immunized with recombinant zona pellucida subunit 3 proteins correlates with Th2 responses and the levels of interleukin 4 expressed by CD4+ cells.	ZP3 POMZP3	1.85e-05	2	150	2	15579591
Pubmed	Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites.	MAPT TTBK1	1.85e-05	2	150	2	32255788
Pubmed	Immunization with recombinant murine cytomegalovirus expressing murine zona pellucida 3 causes permanent infertility in BALB/c mice due to follicle depletion and ovulation failure.	ZP3 POMZP3	1.85e-05	2	150	2	18667753
Pubmed	Antibody responses and infertility in mice following oral immunization with attenuated Salmonella typhimurium expressing recombinant murine ZP3.	ZP3 POMZP3	1.85e-05	2	150	2	9002630
Pubmed	Mutant female mice carrying a single mZP3 allele produce eggs with a thin zona pellucida, but reproduce normally.	ZP3 POMZP3	1.85e-05	2	150	2	9107049
Pubmed	Modification Effect of PARP4 and ERCC1 Gene Polymorphisms on the Relationship between Particulate Matter Exposure and Fasting Glucose Level.	ERCC1 PARP4	1.85e-05	2	150	2	35627777
Pubmed	OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.	OPCML NTM	1.85e-05	2	150	2	12819783
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PTTG1 ZNF609 EP400 APOBR C6orf132 TASOR2 PLEKHG4B NUP155 EPN1 TP53BP2	1.89e-05	430	150	10	35044719
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TROAP DBNL CAMSAP3 PDLIM5 TAB3 MEIOC PDLIM1 UBR5 SIPA1L1 SIPA1L2 SNX9 ELL TP53BP2 FHIP2B	2.11e-05	853	150	14	28718761
Pubmed	Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse.	GATA6 SUZ12 VCAM1	2.18e-05	13	150	3	35796552
Pubmed	Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.	GTF2IRD1 ZP3 MLXIPL POMZP3	2.19e-05	38	150	4	11779826
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	PATZ1 DBNL GSN NCBP3 NUP155 GTF3C2 SIPA1L1 SUZ12 FYB1	3.52e-05	370	150	9	22922362
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	UBR5 SIPA1L1 MYPN SEC16A PEAK1 SIPA1L2 TP53BP2	3.64e-05	209	150	7	36779422
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	EP400 RPN2 SHOC2 DIMT1 GTF3C2 TRIM28 IPO13	3.87e-05	211	150	7	17314511
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	XRN2 EP400 SALL4 TASOR2 NCBP3 LIG1 KMT2D GTF3C2 TRIM28 SUZ12	3.94e-05	469	150	10	27634302
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ZNF609 EP400 CDCA8 DHX8 NCBP3 LIG1 PABPC3 SEC16A TACC1 TP53BP2	4.16e-05	472	150	10	38943005
Pubmed	Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct.	GATA6 LRIG1	5.53e-05	3	150	2	30033638
Pubmed	Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.	MPL SUZ12	5.53e-05	3	150	2	18416604
Pubmed	Localization of the neuronal form of nitric oxide synthase to mouse chromosome 5.	ZP3 POMZP3	5.53e-05	3	150	2	7536496
Pubmed	Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility.	ZP3 POMZP3	5.53e-05	3	150	2	28646452
Pubmed	Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer.	PTTG1 TACC1	5.53e-05	3	150	2	18984771
Interaction	SIRT6 interactions	XRN2 ERCC1 EP400 RRP1B TROAP PATZ1 PDLIM5 TASOR2 LRCH3 SETD2 NUP155 GTF3C2 UBR5 TRIM28 SEC16A SNX9 DHX29	4.17e-06	628	149	17	int:SIRT6
Interaction	PPP1R3A interactions	RRP1B SHOC2 ZFYVE9 MYPN PEAK1 TP53BP2	8.51e-06	65	149	6	int:PPP1R3A
Cytoband	12q13.12	TROAP FKBP11 KMT2D	2.65e-04	38	150	3	12q13.12
Cytoband	7q11.23	GTF2IRD1 ZP3 MLXIPL POMZP3	3.00e-04	97	150	4	7q11.23
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NRCAM OPCML LRIG1 PTPRM NTM MYPN UNC5C VCAM1 MYBPC3	3.46e-07	161	103	9	593
GeneFamily	Immunoglobulin like domain containing	IL11RA NRCAM CEACAM6 FCRLA FCGR2A PTPRM VCAM1	1.18e-04	193	103	7	594
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRB PTPRM PTPRR	2.22e-04	21	103	3	813
GeneFamily	I-set domain containing\|IgLON cell adhesion molecules	OPCML NTM	3.18e-04	5	103	2	1052
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RRP1B MAPT CAMSAP3 TRIM28 ELL TP53BP2	5.93e-04	181	103	6	694
GeneFamily	PDZ domain containing	PDLIM5 PDLIM1 SIPA1L1 SIPA1L2 PDZD4	1.78e-03	152	103	5	1220
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	MPL VPREB1 CEACAM6 SIRPB1 FCGR2C FCGR2A KIR2DL5A VCAM1	1.86e-03	394	103	8	471
GeneFamily	Fibronectin type III domain containing	MPL NRCAM PTPRB PTPRM MYBPC3	2.22e-03	160	103	5	555
GeneFamily	DEAH-box helicases	DHX8 DHX29	3.66e-03	16	103	2	500
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL5B KIR2DL5A	4.63e-03	18	103	2	620
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_large-bowel / Manually curated celltypes from each tissue	CEACAM6 FRYL AK7 PDLIM5 RASGRP1 PTPRM UNC5C CYP4F12 FYB1 IL4I1	4.89e-10	179	148	10	6359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPREB1 SLCO2B1 HMOX1 HAVCR2 FCGR2C LRRC25 FYB1 MYBPC3	2.69e-07	192	148	8	453c11f468117ffdd8c248fee1e5bb1f5401cc33
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HMOX1 FCGR2A SIPA1L1 KLHDC7A SIPA1L2 SNX9 ST18 MYBPC3	3.53e-07	199	148	8	951c2ea5af4756832c2adcec3ee70a7e36331a4e
ToppCell	Control_saline-Hematopoietic_Myeloid\|Control_saline / Treatment groups by lineage, cell group, cell type	SIRPB1 HMOX1 APOBR RAB44 HAVCR2 FCGR2C LRRC25 FYB1	3.53e-07	199	148	8	6be92062cce049a4c98f7311f2500bf1468fc267
ToppCell	distal-2-Endothelial-Artery\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IL11RA GATA6 PTPRB PTPRM PTPRR TACC1 EPAS1 VCAM1	3.53e-07	199	148	8	fa8aaf7a90699e41a7a4cee5614f8c9248110327
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	SKIL PDLIM5 GSN PTPRB PDLIM1 TACC1 TRIM47 EPAS1	3.67e-07	200	148	8	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MPL TROAP CDCA8 KIF24 KMT2D KLHDC7A TRIM47	1.31e-06	164	148	7	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MPL TROAP CDCA8 KIF24 KMT2D KLHDC7A TRIM47	1.31e-06	164	148	7	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 CEACAM6 NTM PLD5 PEAK1	1.70e-06	60	148	5	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 CEACAM6 NTM PLD5 PEAK1	1.70e-06	60	148	5	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO2B1 HMOX1 HAVCR2 FCGR2C LRRC25 FYB1 MYBPC3	2.61e-06	182	148	7	de15a77b8d3527638bea5b04e0b2af03ac93bc18
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRM PTPRR TRIM47 EPAS1 VCAM1	2.61e-06	182	148	7	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRM PTPRR TRIM47 EPAS1 VCAM1	2.61e-06	182	148	7	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	droplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 PTPRB LRIG1 PTPRR TRIM47 EPAS1 VCAM1	2.91e-06	185	148	7	eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO2B1 HMOX1 HAVCR2 FCGR2C LRRC25 FYB1 MYBPC3	3.01e-06	186	148	7	c0a58e43a813441d3a1708236737b15db8bea10e
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 FRYL PTPRB PTPRR TRIM47 EPAS1 VCAM1	3.12e-06	187	148	7	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PHF20 SALL4 F2RL2 PARP4 GLI1 NTM KIF3C	3.23e-06	188	148	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA SLCO2B1 VIT OPCML THBS4 TENM3 GLI1	3.35e-06	189	148	7	6b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA SLCO2B1 VIT OPCML THBS4 TENM3 GLI1	3.35e-06	189	148	7	344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	GATA6 PDLIM5 GSN PTPRB PTPRR EPAS1 VCAM1	3.47e-06	190	148	7	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	Bronchial_Brush-Immune-Luminal_Macrophages\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SLCO2B1 SIRPB1 HMOX1 HAVCR2 LRRC25 FCGR2A FYB1	3.59e-06	191	148	7	88cb6f828407845918c946f8cee5f940cb81800a
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	IL11RA GATA6 PTPRB PTPRR TACC1 ANKRD33B EPAS1	3.59e-06	191	148	7	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA SLCO2B1 VIT OPCML GSN GLI1 VCAM1	3.72e-06	192	148	7	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	IL11RA GATA6 PTPRB PTPRR ANKRD33B EPAS1 VCAM1	3.72e-06	192	148	7	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA SLCO2B1 GATA6 VIT GSN TENM3 GLI1	3.85e-06	193	148	7	025836c5c5a711e477c326559e618e47cae42d11
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTTG1 TROAP CEACAM6 GTF2IRD1 CDCA8 PLEKHG4B NTM	3.98e-06	194	148	7	d790cfff3664e46fe2fd2f6b0c26896799927845
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 CEACAM6 PLEKHG4B UBR5 NTM IPO13 FHIP2B	3.98e-06	194	148	7	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 CEACAM6 PLEKHG4B UBR5 NTM IPO13 FHIP2B	3.98e-06	194	148	7	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL11RA GATA6 PTPRB PTPRM PTPRR TACC1 EPAS1	4.12e-06	195	148	7	83da75d210ae9c2a94018d70cb9e833b37004c4e
ToppCell	Bronchial_Brush-Immune\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SLCO2B1 APOBR HAVCR2 LRRC25 FCGR2A FYB1 IL4I1	4.40e-06	197	148	7	b78d277a1d80ef27c11593ffc68ff8a8abae111f
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SLCO2B1 HMOX1 HAVCR2 FCGR2C SIPA1L2 TRIM47 IL4I1	4.40e-06	197	148	7	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PTTG1 TROAP C21orf58 CEACAM6 CDCA8 LIG1 THBS4	4.40e-06	197	148	7	bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO2B1 HMOX1 APOBR HAVCR2 FCGR2C LRRC25 FYB1	4.55e-06	198	148	7	79c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCell	Control_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|Control_saline / Treatment groups by lineage, cell group, cell type	SIRPB1 HMOX1 APOBR HAVCR2 FCGR2C LRRC25 FYB1	4.55e-06	198	148	7	c15ab0660a6de445a83396cf70860ea39868914d
ToppCell	Control_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages\|Control_saline / Treatment groups by lineage, cell group, cell type	SIRPB1 HMOX1 APOBR HAVCR2 FCGR2C LRRC25 FYB1	4.55e-06	198	148	7	684f2dd5db889f118b5218ee23733cc1361272c2
ToppCell	PSB-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SLCO2B1 HMOX1 HAVCR2 LRRC25 FCGR2A FYB1 IL4I1	4.55e-06	198	148	7	437e2f84b64d99928aedbab7366ff0ec91e74038
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	LAMA5 PDLIM5 GSN DHX8 PTPRB EPAS1 VCAM1	4.70e-06	199	148	7	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	PSB-critical-LOC-Myeloid-Macrophage\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SLCO2B1 HMOX1 HAVCR2 LRRC25 FCGR2A FYB1 IL4I1	4.70e-06	199	148	7	eada9bcac5c113561b806bb800cd53c6bb78e16a
ToppCell	Non-neuronal-Postmitotic\|World / Primary Cells by Cluster	SLCO2B1 HMOX1 GSN HAVCR2 FCGR2A FYB1 EPAS1	4.70e-06	199	148	7	f6a9119ad32d9f0173c432de353b5315a7cf01ad
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 SIRPB1 HMOX1 APOBR HAVCR2 LRRC25 FCGR2A	4.70e-06	199	148	7	7648860058eec66019b574ad840d6f5cfa4476d9
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Transverse / Region, Cell class and subclass	SLCO2B1 HMOX1 GSN MLXIPL LRRC25 FCGR2A SIPA1L2	4.70e-06	199	148	7	facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell	medial-2-Endothelial-Artery\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IL11RA GATA6 PTPRB PTPRM PTPRR EPAS1 VCAM1	4.70e-06	199	148	7	53c17c0493f82351a039bc64def191311e0f4951
ToppCell	medial-Endothelial-Artery-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IL11RA GATA6 PTPRB PTPRM PTPRR EPAS1 VCAM1	4.70e-06	199	148	7	c455f5a2802f2ec6f0e24266de1aaf3203ca8c78
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 APOBR HAVCR2 LRRC25 FCGR2A IL4I1 ST18	4.70e-06	199	148	7	c72279fa3ca2ebc42a1446507673df154b8033c7
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 SIRPB1 HMOX1 APOBR HAVCR2 LRRC25 FCGR2A	4.70e-06	199	148	7	91c72e06a7416671977430211c57938e39e8195e
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 SIRPB1 HMOX1 HAVCR2 LRRC25 FCGR2A IL4I1	4.70e-06	199	148	7	368e2bafae00ce8e9c6ea480f81b78f96b680acd
ToppCell	medial-Endothelial-Artery\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IL11RA GATA6 PTPRB PTPRM PTPRR EPAS1 VCAM1	4.70e-06	199	148	7	341c0be18bec66f4cc8bda232dce54edb34b9cda
ToppCell	Transverse-(6)_Macrophage-(61)_LYVE1_Macrophage\|Transverse / shred on region, Cell_type, and subtype	SLCO2B1 HMOX1 GSN MLXIPL LRRC25 FCGR2A SIPA1L2	4.70e-06	199	148	7	dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCell	distal-Endothelial-Artery-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IL11RA GATA6 PTPRB PTPRR TACC1 EPAS1 VCAM1	4.70e-06	199	148	7	3788f3218356aaaa10684e48d63757037f8a3a3c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLCO2B1 PDLIM5 PDLIM1 PTPRM SIPA1L2 IL4I1 EPAS1	4.86e-06	200	148	7	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SLCO2B1 PDLIM5 PDLIM1 PTPRM IL4I1 EPAS1 VCAM1	4.86e-06	200	148	7	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 SIRPB1 HMOX1 APOBR HAVCR2 LRRC25 FCGR2A	4.86e-06	200	148	7	cc3cdfc4636d8892500ce60518c5ccc100b9e5df
ToppCell	(51)_cDC1\|World / shred on Cell_type and subtype	HMOX1 APOBR GSN PLEKHG4B HAVCR2 ST18 VCAM1	5.53e-06	204	148	7	a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	VPREB1 THAP8 MLXIPL GLI1 PKHD1	1.64e-05	95	148	5	3699ea16660a22ea79fecfea56ece2dfb0f13467
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	VPREB1 THAP8 MLXIPL GLI1 PKHD1	1.64e-05	95	148	5	cbfe615d880913bafaf5e7e8d24c3ec14a9351ce
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	VPREB1 THAP8 MLXIPL GLI1 PKHD1	1.64e-05	95	148	5	27ac23b87747434a3084cc087e7b884e68f0eab9
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 HMOX1 HAVCR2 RASGRP1 PTPRM VCAM1	1.97e-05	166	148	6	91eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 CEACAM6 PLEKHG4B NTM IPO13 FHIP2B	2.18e-05	169	148	6	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 CEACAM6 PLEKHG4B NTM IPO13 FHIP2B	2.18e-05	169	148	6	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA NRCAM DAP GSN TACC1 PEAK1	2.57e-05	174	148	6	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERCC1 GATA6 TENM3 PDLIM1 PLD5 PEAK1	2.65e-05	175	148	6	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	THBS4 PTPRR PABPC3 ZFHX2 KIF3C PDZD4	2.65e-05	175	148	6	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERCC1 GATA6 TENM3 PDLIM1 PLD5 PEAK1	2.65e-05	175	148	6	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLCO2B1 HMOX1 GSN HAVCR2 TRIM47 IL4I1	2.92e-05	178	148	6	e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ZCCHC12 SIRPB1 TTBK1 PTPRM SIPA1L2 SNX9	2.92e-05	178	148	6	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 HMOX1 HAVCR2 LRRC25 PTPRM VCAM1	2.92e-05	178	148	6	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	GATA6 PTPRB PTPRM PTPRR EPAS1 VCAM1	3.01e-05	179	148	6	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SALL4 PLEKHG4B GTF3C2 PKHD1 ZFHX2	3.05e-05	108	148	5	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA SLCO2B1 VIT OPCML GSN GLI1	3.11e-05	180	148	6	9adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTTG1 TROAP CAMSAP3 CDCA8 C6orf132 SACM1L	3.11e-05	180	148	6	271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 TROAP C21orf58 CDCA8 KIF24 LIG1	3.11e-05	180	148	6	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAMSAP3 GATA6 PTPRB PTPRR TRIM47 EPAS1	3.20e-05	181	148	6	2c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GTF2IRD1 APOBR GSN SIPA1L2 IL4I1 MYBPC3	3.20e-05	181	148	6	6771f2c72073c59aab905945a619907b7fd0fd77
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA NRCAM GSN TACC1 PEAK1 VCAM1	3.30e-05	182	148	6	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRYL PTPRB PDLIM1 PTPRM PTPRR EPAS1	3.30e-05	182	148	6	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SALL4 CDCA8 PLEKHG4B PKHD1 ZFHX2	3.34e-05	110	148	5	c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP FCRLA F2RL2 CDCA8 HAVCR2 NUP155	3.41e-05	183	148	6	ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP FCRLA F2RL2 CDCA8 HAVCR2 NUP155	3.41e-05	183	148	6	263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PTTG1 TROAP C21orf58 CDCA8 LIG1 LRIG1	3.41e-05	183	148	6	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 PTPRB PTPRM PTPRR TRIM47 VCAM1	3.41e-05	183	148	6	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP FCRLA F2RL2 CDCA8 HAVCR2 NUP155	3.41e-05	183	148	6	e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCRLA ZP3 THBS4 PKHD1 EPAS1 SEPTIN12	3.41e-05	183	148	6	bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCRLA ZP3 THBS4 PKHD1 EPAS1 SEPTIN12	3.41e-05	183	148	6	4c325ee6da070513097a11445ec95b0415ffd8a2
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCDHGA3 GATA6 LAMA5 PTPRB PTPRR TRIM47	3.51e-05	184	148	6	8bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PTPRB PDLIM1 PTPRM PTPRR ANKRD33B EPAS1	3.51e-05	184	148	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCDHGA3 GATA6 LAMA5 PTPRB PTPRR TRIM47	3.51e-05	184	148	6	f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CPEB2 MLXIPL TENM3 PTPRM PKHD1 ST18	3.62e-05	185	148	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 PTPRB PTPRM PTPRR TRIM47 EPAS1	3.73e-05	186	148	6	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRM PTPRR TRIM47 EPAS1	3.73e-05	186	148	6	b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRR TRIM47 EPAS1 VCAM1	3.73e-05	186	148	6	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRM PTPRR TRIM47 EPAS1	3.73e-05	186	148	6	8a8ed1502542d4895cba3fd5d534256206578716
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TROAP C21orf58 CDCA8 KIF24 TENM3 NTM	3.84e-05	187	148	6	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRR TRIM47 EPAS1 VCAM1	3.84e-05	187	148	6	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PTPRB PDLIM1 PTPRM PTPRR EPAS1 VCAM1	3.84e-05	187	148	6	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASAH2 LCMT2 PTPRB PTPRM SEC16A EPAS1	3.84e-05	187	148	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASAH2 LCMT2 PTPRB PTPRM SEC16A EPAS1	3.84e-05	187	148	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TROAP C21orf58 CDCA8 KIF24 TENM3 NTM	3.84e-05	187	148	6	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	FRYL PTPRB PTPRM TACC1 SIPA1L2 EPAS1	3.84e-05	187	148	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA6 PTPRB PTPRR TRIM47 EPAS1 VCAM1	3.84e-05	187	148	6	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 TROAP C21orf58 CDCA8 KIF24 LIG1	3.84e-05	187	148	6	9351fa87b69a951af85b10bf91fe9b1cce8c0517
Disease	malaria (implicated_via_orthology)	HMOX1 FCGR2C FCGR2A	9.75e-06	9	146	3	DOID:12365 (implicated_via_orthology)
Disease	rheumatic myocarditis (is_marker_for)	GSN VCAM1	1.45e-04	4	146	2	DOID:8481 (is_marker_for)
Disease	Malignant Cystosarcoma Phyllodes	SETD2 KMT2D	2.41e-04	5	146	2	C0600066
Disease	Phyllodes Tumor	SETD2 KMT2D	2.41e-04	5	146	2	C0010701
Disease	thrombocytopenia (is_implicated_in)	MPL FCGR2A FYB1	3.18e-04	27	146	3	DOID:1588 (is_implicated_in)
Disease	essential thrombocythemia (is_marker_for)	MPL VCAM1	3.60e-04	6	146	2	DOID:2224 (is_marker_for)
Disease	triacylglycerol 54:3 measurement	GTF2IRD1 OPCML MYPN	4.82e-04	31	146	3	EFO_0010421
Disease	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	FCRLA FCGR2A	5.02e-04	7	146	2	EFO_0008211
Disease	docosahexaenoic acid measurement, sex interaction measurement	GATA6 PTPRM	5.02e-04	7	146	2	EFO_0007761, EFO_0008343
Disease	aspartate aminotransferase measurement	MAPT FCRLA SKIL SHOC2 OPCML FCGR2C FCGR2A PTPRR GLI1 MYPN CARS2 ELL MYBPC3	5.76e-04	904	146	13	EFO_0004736
Disease	Williams Syndrome	GTF2IRD1 MLXIPL	6.68e-04	8	146	2	C0175702
Disease	neutropenia (is_implicated_in)	FCGR2A C5	6.68e-04	8	146	2	DOID:1227 (is_implicated_in)
Disease	pulmonary hypertension (biomarker_via_orthology)	GATA6 HMOX1 EPAS1 VCAM1	6.80e-04	80	146	4	DOID:6432 (biomarker_via_orthology)
Disease	liver cancer (is_marker_for)	SLCO2B1 SETD2	8.56e-04	9	146	2	DOID:3571 (is_marker_for)
Disease	Amyloidosis	HMOX1 GSN	1.07e-03	10	146	2	C0002726
Disease	Paroxysmal atrial fibrillation	AKAP6 MAPT LRIG1 MYPN KIF3C	1.10e-03	156	146	5	C0235480
Disease	familial atrial fibrillation	AKAP6 MAPT LRIG1 MYPN KIF3C	1.10e-03	156	146	5	C3468561
Disease	Persistent atrial fibrillation	AKAP6 MAPT LRIG1 MYPN KIF3C	1.10e-03	156	146	5	C2585653
Disease	asthma exacerbation measurement	ERCC1 PTPRM NTM VCAM1	1.19e-03	93	146	4	EFO_0007614
Disease	Atrial Fibrillation	AKAP6 MAPT LRIG1 MYPN KIF3C	1.23e-03	160	146	5	C0004238
Disease	systemic lupus erythematosus (implicated_via_orthology)	RASGRP1 FCGR2C FCGR2A	1.27e-03	43	146	3	DOID:9074 (implicated_via_orthology)
Disease	ovary epithelial cancer (is_implicated_in)	AKAP6 ERCC1	1.30e-03	11	146	2	DOID:2152 (is_implicated_in)
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D UBR5	1.30e-03	11	146	2	DOID:3717 (is_implicated_in)
Disease	factor VIII deficiency (is_implicated_in)	HMOX1 FCGR2A	1.30e-03	11	146	2	DOID:12134 (is_implicated_in)
Disease	QRS complex, QRS duration	LRIG1 SIPA1L1 EPAS1	1.45e-03	45	146	3	EFO_0005054, EFO_0005055
Disease	carbohydrate measurement	OPCML GSN PTPRM	1.54e-03	46	146	3	EFO_0004998
Disease	systemic lupus erythematosus (is_marker_for)	TAB3 FCGR2A VCAM1	1.64e-03	47	146	3	DOID:9074 (is_marker_for)
Disease	reaction time measurement	AKAP6 MAPT VIT MLXIPL SETD2 KMT2D NTM ZNF648 PKHD1 EPAS1	1.67e-03	658	146	10	EFO_0008393
Disease	Sjogren's Syndrome	PTTG1 FCGR2A	1.83e-03	13	146	2	C1527336
Disease	Sicca Syndrome	PTTG1 FCGR2A	1.83e-03	13	146	2	C0086981
Disease	ventricular septal defect (is_implicated_in)	GATA6 SALL4	2.13e-03	14	146	2	DOID:1657 (is_implicated_in)
Disease	cerebellum cortex volume change measurement	PTPRM EPAS1	2.13e-03	14	146	2	EFO_0021497
Disease	coffee consumption measurement	AKAP6 OPCML MLXIPL MYPN PKHD1	2.16e-03	182	146	5	EFO_0006781
Disease	response to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy	PTPRB LRIG1 ZNF648	2.45e-03	54	146	3	EFO_0000180, EFO_0003100, GO_0061479
Disease	brain edema (biomarker_via_orthology)	HMOX1 C5	2.45e-03	15	146	2	DOID:4724 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	AKAP6 NRCAM SLCO2B1 PER1 HMOX1 GSN SETD2 KMT2D GLI1 SIPA1L1 KLHDC7A TP53BP2 PDZD4	2.68e-03	1074	146	13	C0006142
Disease	refractive error, age at onset, Myopia	AKAP6 PTPRR NTM PLD5 ST18	2.79e-03	193	146	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Chromosome Aberrations	ERCC1 EPAS1	2.79e-03	16	146	2	C0008625
Disease	pneumonia (is_implicated_in)	HMOX1 C5	2.79e-03	16	146	2	DOID:552 (is_implicated_in)
Disease	coffee consumption, cups of coffee per day measurement	OPCML MLXIPL	2.79e-03	16	146	2	EFO_0004330, EFO_0006782
Disease	Autosome Abnormalities	ERCC1 EPAS1	2.79e-03	16	146	2	C0004403
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR2C FCGR2A	3.15e-03	17	146	2	EFO_0021969
Disease	alcohol consumption measurement	AKAP6 MAPT SELENON OPCML MLXIPL PTPRB DIMT1 LRRC25 NTM PKHD1 ANKRD11 PEAK1 ST18 MYBPC3	3.52e-03	1242	146	14	EFO_0007878
Disease	cystic fibrosis (is_marker_for)	HMOX1 HAVCR2 C5	3.63e-03	62	146	3	DOID:1485 (is_marker_for)
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	RASGRP1 FCGR2A C5	3.79e-03	63	146	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	Ulcerative Colitis	DAP FCGR2A VCAM1	3.79e-03	63	146	3	C0009324
Disease	interstitial lung disease	MAPT NTM EPAS1	4.51e-03	67	146	3	EFO_0004244
Disease	mean platelet volume	PHF20 PCDHGA3 FRYL SIRPB1 APOBR PDLIM5 MLXIPL SETD2 MEIOC PDLIM1 ANKRD11 MYBPC3	4.87e-03	1020	146	12	EFO_0004584

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPLLGDARFQKSPPD	TACC1	276	O75410
GDNDRLKPPPQASFT	C2orf49	121	Q9BVC5
QKPEGRTVAFPSTHP	EP400	1471	Q96L91
LPTFAKPTAEPGQDN	EP400	2351	Q96L91
PSAISPGENSKSRFP	EPAS1	786	Q99814
SPPKPTVFISGVIAR	DAP	51	P51397
QFRKPAPGATDAVPS	ELL	161	P55199
TPSPEGVFSSLQAKP	ANKRD11	1876	Q6UB99
GVFSSLQAKPSPSPR	ANKRD11	1881	Q6UB99
PSGPFVLSSPRKTAQ	RASGRP1	686	O95267
TDPVKAAQFEPPGRQ	FCGR2A	251	P12318
DQAAAFTLPPPGVRK	DHX29	911	Q7Z478
TSRPKAVTFSPDLGP	CAMSAP3	676	Q9P1Y5
GSKQESPPAAAVRPF	TP53BP2	571	Q13625
VRVSKAPAPTFQPER	ANKRD33B	426	A6NCL7
APRTPPGVTFSAKDN	RAB44	431	Q7Z6P3
RGPVDTKPSNSLIPF	CDC42BPG	801	Q6DT37
FGKPSLSAQPGPTVR	KIR2DL5A	121	Q8N109
FPLPKAAPNGSSDIR	ABCC10	951	Q5T3U5
SPKPGFLASVIPVDR	IL11RA	401	Q14626
LQTDPLPPARFGVSK	PTPRB	106	P23467
RQPKGPDPDSLSSQF	LRCH3	391	Q96II8
PESLKGQSIFSVPPE	LRIG1	471	Q96JA1
RTQEATHPVKTGFPP	NMS	76	Q5H8A3
KGPVPTFQPFQRSIS	NELFE	101	P18615
PTGVPVRSGDATFPK	NTM	26	Q9P121
RPPTFLTPEGNASNK	NRCAM	266	Q92823
YGSRSAPKPQVAVPS	LRRC25	221	Q8N386
TVANLSRGPEPPFFK	ASAH2	621	Q9NR71
GPDVPTISPSKANYR	CEACAM6	236	P40199
PGLTPRFDSRVFKTP	CDCA8	186	Q53HL2
VPPGVAKPLFRSTQS	ERCC1	31	P07992
FGKPSLSAQPGPTVR	KIR2DL5B	121	Q8NHK3
NPRAAPGELPKTFTF	KIF3C	46	O14782
STDPVKAAQFEPPGR	FCGR2C	256	P31995
PQSRPRLPATGTFKA	PER1	571	O15534
SGFQTPAKPRLAPAT	FHIP2B	511	Q86V87
EPPSSTNTPGSLRKF	PDZD4	301	Q76G19
RNTGNFRPPVAKKPT	PEAK1	56	Q9H792
ERNFSGSIPAVTPPK	FAM218A	96	Q96MZ4
PESGLPKNPSVVFSS	FRYL	2371	O94915
QEELASGTPPARFPK	FYB1	301	O15117
PEKAFSSNPVVRREP	NCBP3	501	Q53F19
PNIPFTSAPKVSGKR	KIF24	616	Q5T7B8
VSPSRAKAPVNTYGP	GLI1	936	P08151
NKAPRPFGSVSSPKV	PDLIM5	126	Q96HC4
PSTEPAFITVPQRGF	LAMA5	971	O15230
PDVFTVSVGNLPPKA	PARP4	711	Q9UKK3
RLPPGFSASSTVEKP	NUP155	391	O75694
FQNKPSAIRPGAPRV	PABPC3	441	Q9H361
LEGPAPPFVTASNVK	NUTM1	126	Q86Y26
GNIEPFVSIPTPREK	PTPRR	351	Q15256
PIKTFRGAPPNSFEE	F2RL2	36	O00254
PTGVPVRSGDATFPK	OPCML	26	Q14982
FPSVASSAPPLTGKR	PATZ1	251	Q9HBE1
TVPGTRFPIKTAFDP	PCDHGA3	146	Q9Y5H0
QGARSSAAFPPKTSP	C6orf132	746	Q5T0Z8
SRGAKLSPFAPEQPE	GATA6	131	Q92908
PQKGTRFRPLSFEVP	GMPPA	11	Q96IJ6
KRGFPPSVPADAVVQ	FKBP11	121	Q9NYL4
SGNVIAPPKFTRSTP	CPEB2	171	Q7Z5Q1
PPQAFPTQRSGSIKE	C21orf58	226	P58505
PPGPNREFSITVVQK	FCRLA	121	Q7L513
GIISFPDFKIPSNPR	C5	181	P01031
DPENSKGRSPLAFIP	CYP4F12	446	Q9HCS2
PTRKTPESFLGPNAA	EPN1	466	Q9Y6I3
VPKELRSFPAPQGTL	KLHDC7A	746	Q5VTJ3
ETPRGKPPLNTRSQA	HMOX1	251	P09601
RTPITVVKQGFEPPS	GSN	741	P06396
TVTRPFQGLIPKPDE	GTF2IRD1	776	Q9UHL9
PVFKASTPRERNAGP	C4orf54	896	D6RIA3
PPPLTASGVFSKFRD	LIG1	396	P18858
KDVPPSAVTRPIFGI	SACM1L	46	Q9NTJ5
APFTLKPDGTRVLPN	SALL4	311	Q9UJQ4
PGFPSARLSPEQKDT	IPO13	911	O94829
TSISSPQPGKLRSPF	DBNL	271	Q9UJU6
QTRIFDPAPPGSRKV	DHX8	821	Q14562
VGKNNFRPPPKVESS	DIMT1	191	Q9UNQ2
VSTPRFGKTFDAPPA	PTTG1	41	O95997
FVRQVKSKSPPSAGP	PTPRM	1076	P28827
PNKPSGFRSVKAPVT	PDLIM1	231	O00151
TASGPAVKRITFSPP	IL4I1	321	Q96RQ9
QEPSPPKAFAVTRCG	PHF20	566	Q9BVI0
FQSAGSPVPSPVRTL	PUSL1	181	Q8N0Z8
SLESLRVGAKPPPFQ	SYDE2	86	Q5VT97
PTFSDKGVPFPVLQR	HSF5	246	Q4G112
PTFGFQRPIKTRSGP	MEIOC	736	A2RUB1
VPSGKYVVDNSRPPT	REXO1	216	Q8N1G1
PIPSLPDKQVTGRFE	SNX9	306	Q9Y5X1
ASLKEPEGPRSPAVF	CARS2	436	Q9HA77
PGPPRELSFTKSSQA	TRIM47	351	Q96LD4
KPFTVEISPGPRIAA	VCAM1	311	P19320
VPSIFSRGPPAKSQR	THAP8	81	Q8NA92
PLSSGKSQPAPAEFR	MPST	141	P25325
SPTGPSRVAFDPEQK	RRP1B	706	Q14684
PKEPSPSLTRVGANF	PLD5	26	Q8N7P1
PRTFPQNGSVLPAKS	SKIL	236	P12757
SRGISSQPKPPFSVN	TAB3	411	Q8N5C8
FPSPARGRTAPDKQQ	PELI3	341	Q8N2H9
PAKVTPAPTRQRDFT	HAVCR2	131	Q8TDQ0
VTNTPIDPSGKFPFI	SIPA1L1	821	O43166
FQEPGALPFTPKSIR	SIPA1L2	711	Q9P2F8
FSVDNTIKRPNPAPG	SHOC2	66	Q9UQ13
VTSPPGVNFTARSKP	PKHD1	3831	P08F94
FFSTGPARPPTKEKV	RNASE9	51	P60153
RGQKASPPTLAPATA	MLXIPL	501	Q9NP71
KPSAPVVSGPAARAT	SIRPB1	146	Q5TFQ8
GSNFSEETKPPRVPK	ST18	206	O60284
EDSPTQPTLPKRGLF	AKAP6	381	Q13023
SKAPGFRPPSQRVST	ANKHD1	2266	Q8IWZ3
VSPFPKQPQVLGTER	APOBR	421	Q0VD83
LPRAFAGPSQKPETI	THBS4	156	P35443
VKASFPSSALPPRTG	ZC3H3	226	Q8IXZ2
TPPGSATAADLRPKQ	TTBK1	1196	Q5TCY1
QFRSTPGGVPSPAVK	ZFHX2	1916	Q9C0A1
SLSPAPETKRPGQAA	SEC16A	2081	O15027
REPEKRPPTVVSNTF	RPN2	531	P04844
GKASPDPQDVRPSVF	SLCO2B1	31	O94956
KTQSFEIPQPDSGPR	PLEKHG4B	726	Q96PX9
KRLPPFETFSQGPTL	SUZ12	341	Q15022
RIKSPFPEQPAVSAG	THSD1	586	Q9NS62
PRPFVKTRFAPQGAV	SELENON	261	Q9NZV5
FPPSGNRSEFPDVKI	SPPL2A	121	Q8TCT8
EPLPGEPTKTNLVTF	STARD5	161	Q9NSY2
KRDQPAFTPSGILTP	XRN2	426	Q9H0D6
DKSQGPQVPPRFSGS	VPREB1	76	P12018
PQVPPRFSGSKDVAR	VPREB1	81	P12018
APASPGQLTTPRTFK	SEPTIN12	331	Q8IYM1
ATLPDNIKFVTPVPG	ZNF609	66	O15014
ETPVQPAFSLPKGER	TROAP	251	Q12815
TKAYQRPPIPGTTAQ	VIT	166	Q6UXI7
PQTAAREATSIPGFP	MAPT	246	P10636
LSGFVRPNPIIVSSP	TENM3	956	Q9P273
YGPRDPKNSTGPTVI	MPL	171	P40238
GFRDQTPAPKTPNRS	SETD2	2046	Q9BYW2
RVFQGLTPTVKPSPV	ZNF621	416	Q6ZSS3
GRAFQKPSKPLSPAE	ZNF648	256	Q5T619
SGVPNPPKARTYTET	GTF3C2	776	Q8WUA4
PLFPRNGTKSPEAAT	TASOR2	676	Q5VWN6
SSEPPFGPRNVIENK	TASOR2	1571	Q5VWN6
RVNPASPSGVFPASV	LCMT2	331	O60294
KRRQAVPPPAGFTDS	TPGS1	6	Q6ZTW0
SSAFKVPRPGPDTLQ	POMZP3	86	Q6PJE2
VTGPSAFSIPLPIRQ	UNC5C	836	O95185
FKVPRPGPDTLQFTV	ZP3	251	P21754
KDPGPTRTFTVVPRA	TM2D3	41	Q9BRN9
SISVPFGGARPKQPS	ZFYVE9	571	O95405
RAVSPVAFQGSPPIV	ZCCHC12	241	Q6PEW1
SQPPVFKVFPGSTTE	TRIM28	501	Q13263
TGGTPKVPDCFQRTP	UBR5	721	O95071
RPQPPEVAFKAGSLA	KMT2D	2471	O14686
FQIVGTLSKPDSPRP	AK7	76	Q96M32
AATTKEPVFIPRPGI	MYBPC3	1151	Q14896
RFNGQATKTPEPSSP	MYPN	631	Q86TC9