Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZNF217 ZNF81 ZNF841 ZNF90 MED1 ZNF626 PRDM4 NKRF	1.01e-05	1244	74	16	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZNF217 ZNF81 ZNF841 ZNF90 MED1 ZNF626 PRDM4 NKRF	1.32e-05	1271	74	16	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZNF217 ZNF81 ZNF841 ZNF90 MED1 ZNF626 PRDM4 NKRF PRDM2	1.85e-05	1459	74	17	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZNF217 ZNF81 ZNF841 ZNF90 ZNF626 PRDM4 NKRF PRDM2	4.80e-05	1412	74	16	GO:0000981
Domain	ZINC_FINGER_C2H2_2	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 GPATCH8 ZNF626 PRDM4 PRDM2	6.71e-09	775	74	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 GPATCH8 ZNF626 PRDM4 PRDM2	6.98e-09	777	74	17	PS00028
Domain	-	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 ZNF626 PRDM4 PRDM2	7.37e-09	679	74	16	3.30.160.60
Domain	zf-C2H2	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 ZNF626 PRDM4 PRDM2	9.83e-09	693	74	16	PF00096
Domain	Znf_C2H2-like	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 GPATCH8 ZNF626 PRDM4 PRDM2	9.98e-09	796	74	17	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 ZNF626 PRDM4 PRDM2	1.00e-08	694	74	16	IPR013087
Domain	Znf_C2H2	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 GPATCH8 ZNF626 PRDM4 PRDM2	1.18e-08	805	74	17	IPR007087
Domain	ZnF_C2H2	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 GPATCH8 ZNF626 PRDM4 PRDM2	1.25e-08	808	74	17	SM00355
Domain	zf-C2H2_6	ZNF486 ZNF562 SCRT1 ZNF493 ZFP64 ZNF841 ZNF90 ZNF626 PRDM2	4.05e-06	314	74	9	PF13912
Domain	-	DST MACF1	2.30e-04	6	74	2	3.90.1290.10
Domain	GAR	DST MACF1	2.30e-04	6	74	2	PS51460
Domain	-	DST MACF1	2.30e-04	6	74	2	3.30.920.20
Domain	GAS_dom	DST MACF1	2.30e-04	6	74	2	IPR003108
Domain	GAS2	DST MACF1	2.30e-04	6	74	2	PF02187
Domain	GAS2	DST MACF1	2.30e-04	6	74	2	SM00243
Domain	Plectin_repeat	DST MACF1	3.21e-04	7	74	2	IPR001101
Domain	Plectin	DST MACF1	3.21e-04	7	74	2	PF00681
Domain	PLEC	DST MACF1	3.21e-04	7	74	2	SM00250
Domain	FERM_central	JAK1 PTPN14 FRMPD1	9.65e-04	49	74	3	IPR019748
Domain	FERM_domain	JAK1 PTPN14 FRMPD1	9.65e-04	49	74	3	IPR000299
Domain	FERM_1	JAK1 PTPN14 FRMPD1	1.02e-03	50	74	3	PS00660
Domain	FERM_2	JAK1 PTPN14 FRMPD1	1.02e-03	50	74	3	PS00661
Domain	FERM_3	JAK1 PTPN14 FRMPD1	1.02e-03	50	74	3	PS50057
Domain	Band_41_domain	JAK1 PTPN14 FRMPD1	1.02e-03	50	74	3	IPR019749
Domain	B41	JAK1 PTPN14 FRMPD1	1.02e-03	50	74	3	SM00295
Domain	SH3	EPS8 FRK DST MACF1 VAV1	1.67e-03	216	74	5	PS50002
Domain	SH3_domain	EPS8 FRK DST MACF1 VAV1	1.81e-03	220	74	5	IPR001452
Domain	CH	DST MACF1 VAV1	2.19e-03	65	74	3	SM00033
Domain	CH	DST MACF1 VAV1	2.70e-03	70	74	3	PF00307
Domain	-	DST MACF1 VAV1	2.81e-03	71	74	3	1.10.418.10
Domain	KRAB	ZNF708 ZNF486 ZNF562 ZNF81 ZNF90 ZNF626	2.95e-03	358	74	6	PS50805
Domain	KRAB	ZNF708 ZNF486 ZNF562 ZNF81 ZNF90 ZNF626	2.95e-03	358	74	6	PF01352
Domain	CH	DST MACF1 VAV1	3.04e-03	73	74	3	PS50021
Domain	CH-domain	DST MACF1 VAV1	3.29e-03	75	74	3	IPR001715
Domain	Znf_C2H2_jaz	HIVEP2 GPATCH8	3.40e-03	22	74	2	IPR022755
Domain	zf-C2H2_jaz	HIVEP2 GPATCH8	3.40e-03	22	74	2	PF12171
Domain	KRAB	ZNF708 ZNF486 ZNF562 ZNF81 ZNF90 ZNF626	3.42e-03	369	74	6	SM00349
Domain	KRAB	ZNF708 ZNF486 ZNF562 ZNF81 ZNF90 ZNF626	3.47e-03	370	74	6	IPR001909
Domain	Actinin_actin-bd_CS	DST MACF1	3.71e-03	23	74	2	IPR001589
Domain	G_patch	GPATCH8 NKRF	3.71e-03	23	74	2	SM00443
Domain	G_patch_dom	GPATCH8 NKRF	3.71e-03	23	74	2	IPR000467
Domain	Spectrin	DST MACF1	3.71e-03	23	74	2	PF00435
Domain	G_PATCH	GPATCH8 NKRF	3.71e-03	23	74	2	PS50174
Domain	G-patch	GPATCH8 NKRF	3.71e-03	23	74	2	PF01585
Domain	ACTININ_2	DST MACF1	3.71e-03	23	74	2	PS00020
Domain	ACTININ_1	DST MACF1	3.71e-03	23	74	2	PS00019
Domain	SH3_1	EPS8 FRK DST VAV1	4.09e-03	164	74	4	PF00018
Domain	EF-hand_7	DST LPCAT2 MACF1	4.67e-03	85	74	3	PF13499
Domain	Spectrin_repeat	DST MACF1	5.87e-03	29	74	2	IPR002017
Domain	Ubiquitin-rel_dom	RADIL PTPN14 FRMPD1 USP24	6.14e-03	184	74	4	IPR029071
Domain	Spectrin/alpha-actinin	DST MACF1	7.11e-03	32	74	2	IPR018159
Domain	SPEC	DST MACF1	7.11e-03	32	74	2	SM00150
Domain	FERM_N	PTPN14 FRMPD1	7.55e-03	33	74	2	PF09379
Domain	FERM_N	PTPN14 FRMPD1	7.55e-03	33	74	2	IPR018979
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF708 ZNF486 ZNF562 ZNF493 ZNF841 ZNF90 ZNF626	1.36e-07	181	75	7	37372979
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COL3A1 JAK1 PTPN14 DST DENND6B MACF1 ZNF217 CLSTN1	6.13e-07	332	75	8	37433992
Pubmed	Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.	C5 C6	4.59e-06	2	75	2	2808363
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	4.59e-06	2	75	2	11002341
Pubmed	Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.	CPB2 C5	4.59e-06	2	75	2	17105819
Pubmed	Crystal structure of C5b-6 suggests structural basis for priming assembly of the membrane attack complex.	C5 C6	4.59e-06	2	75	2	22500023
Pubmed	Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels.	C5 C6	4.59e-06	2	75	2	35960843
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.37e-05	3	75	2	12399109
Pubmed	Carboxypeptidase B2 and N play different roles in regulation of activated complements C3a and C5a in mice.	CPB2 C5	1.37e-05	3	75	2	29383821
Pubmed	Carboxypeptidase B2 deficiency reveals opposite effects of complement C3a and C5a in a murine polymicrobial sepsis model.	CPB2 C5	1.37e-05	3	75	2	25851247
Pubmed	Enhanced abdominal aortic aneurysm formation in thrombin-activatable procarboxypeptidase B-deficient mice.	CPB2 C5	1.37e-05	3	75	2	20431069
Pubmed	Formation and structure of the C5b-7 complex of the lytic pathway of complement.	C5 C6	1.37e-05	3	75	2	1387399
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PPIG DST ZBTB17 ORC3 PHF3 ZFP64 AATF HCFC2 GPATCH8 MED1 NKRF PRDM2	2.00e-05	1294	75	12	30804502
Pubmed	Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N.	CPB2 C5	2.75e-05	4	75	2	11939578
Pubmed	Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.	C5 C6	2.75e-05	4	75	2	25735751
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	2.75e-05	4	75	2	8954775
Pubmed	A genetic linkage map of the mouse: current applications and future prospects.	BMP6 DST VAV1	3.75e-05	30	75	3	8211130
Pubmed	Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.	TGFB1I1 COL3A1 BMP6 DST MACF1	4.17e-05	177	75	5	22560297
Pubmed	Predominant role for C5b-9 in renal ischemia/reperfusion injury.	C5 C6	4.57e-05	5	75	2	10811844
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ORC3 PHF3 AATF GPATCH8 MED1 DHX29 NKRF	4.68e-05	440	75	7	34244565
Pubmed	Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.	C5 C6	6.84e-05	6	75	2	22832194
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS8 DST ORC3 PHF3 MACF1 AATF ZNF217 HCFC2 GPATCH8 MED1 DHX29 NKRF	8.19e-05	1497	75	12	31527615
Pubmed	SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.	JAK1 VAV1	9.57e-05	7	75	2	15456882
Pubmed	Prothrombotic polymorphisms, mutations, and their association with pediatric non-cardioembolic stroke in Asian-Indian patients.	MTRR CPB2	9.57e-05	7	75	2	18836720
Pubmed	Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer.	MTRR PRDM2	9.57e-05	7	75	2	19843671
Pubmed	CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.	C5 C6	9.57e-05	7	75	2	30552328
Pubmed	Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.	C5 C6	9.57e-05	7	75	2	19864026
Pubmed	Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer.	MTRR PRDM2	9.57e-05	7	75	2	20960050
Pubmed	Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation.	C5 C6	9.57e-05	7	75	2	30910380
Pubmed	Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury.	C5 C6	1.27e-04	8	75	2	17536017
Pubmed	Molecular organization and function of the complement system.	C5 C6	1.27e-04	8	75	2	3052276
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	PPIG ORC3 PHF3 AATF VAV1 NKRF	1.51e-04	370	75	6	22922362
Pubmed	Loss of ADAMTS19 causes progressive non-syndromic heart valve disease.	COL3A1 ADAMTS19	1.64e-04	9	75	2	31844321
Pubmed	Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells.	C5 C6	1.64e-04	9	75	2	19162005
Pubmed	Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.	C5 C6	1.64e-04	9	75	2	18947875
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	DST MACF1 CDK5RAP2 CLSTN1	1.84e-04	130	75	4	12421765
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C5 C6	2.04e-04	10	75	2	30429287
Pubmed	The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.	DST MACF1	2.49e-04	11	75	2	16815997
Pubmed	Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.	ZFP64 ZNF217	2.49e-04	11	75	2	12881723
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PHF3 FRMPD1 MACF1 BOD1L1 HERC3 GPATCH8	2.52e-04	407	75	6	12693553
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PPIG PHF3 USP24 ZNF217 GPATCH8 MED1 DHX29 PRDM2	2.63e-04	774	75	8	15302935
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RADIL PTPN14 HIVEP2 DST PHF3 CCDC138 MACF1 BOD1L1	5.34e-04	861	75	8	36931259
Pubmed	Novel cell lines promote the discovery of genes involved in early heart development.	TGFB1I1 JAK1	6.87e-04	18	75	2	11437454
Pubmed	Tissue-specific expression and mapping of the Cox7ah gene in mouse.	CYP1A2 LIPE	6.87e-04	18	75	2	9615220
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	EPS8 DST PHF3 BOD1L1 MED1 LRRFIP2	7.94e-04	506	75	6	30890647
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST MACF1	8.50e-04	20	75	2	21689717
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	LPCAT2 PHF3 MTRR MACF1 AATF MED1 DHX29	9.59e-04	724	75	7	36232890
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	BOD1L1 HCFC2	1.03e-03	22	75	2	26886794
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	PHF3 CDK5RAP2 BOD1L1 PRDM2	1.08e-03	208	75	4	33230847
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PTPN14 PHF3 USP24 BOD1L1 MED1 NKRF	1.21e-03	549	75	6	38280479
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	PHF3 MACF1 AATF MED1 DHX29 NKRF LRRFIP2	1.26e-03	759	75	7	35915203
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	HIVEP2 CCDC138 AATF GPATCH8	1.47e-03	226	75	4	25900982
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DST PHF3 PRDM4 NKRF	1.64e-03	233	75	4	37704626
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JAK1 HIVEP2 DST DENND6B MACF1 MIGA1 ZNF841 PRDM4 LNX1	1.76e-03	1285	75	9	35914814
Pubmed	Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.	ORC3 CDK5RAP2	1.79e-03	29	75	2	22898775
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF493 ZNF626	1.79e-03	29	75	2	14563677
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C5 C6	2.05e-03	31	75	2	19344414
Cytoband	19p12	ZNF708 ZNF486 ZNF493 ZNF90 ZNF626	4.01e-07	90	75	5	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF708 ZNF486 ZNF493 ZNF90 ZNF626	1.81e-06	122	75	5	chr19p12
Cytoband	1q44	OR2L2 OR2L8 OR2L3 OR2L5	3.33e-05	110	75	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2L2 OR2L8 OR2L3 OR2L5	6.01e-05	128	75	4	chr1q44
Cytoband	20q13.2	ZFP64 ZNF217	9.00e-04	27	75	2	20q13.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF708 ZNF486 HIVEP2 ZNF562 SCRT1 ZBTB17 ZNF493 ZNF648 ZFP64 ZNF217 ZNF81 ZNF841 ZNF90 ZNF626 PRDM4	6.53e-09	718	59	15	28
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	2.89e-04	8	59	2	939
GeneFamily	Olfactory receptors, family 2	OR2L2 OR2L8 OR2L3 OR2L5	5.05e-04	113	59	4	149
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	JAK1 PTPN14 FRMPD1	5.80e-04	50	59	3	1293
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM4 PRDM2	1.38e-03	17	59	2	1197
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	GPATCH8 NKRF	2.32e-03	22	59	2	579
GeneFamily	Complement system\|Sushi domain containing	C5 C6	6.14e-03	36	59	2	492
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	EPS8 PPIG DST PHF3 BOD1L1 XAF1 LRRFIP2	4.58e-08	199	75	7	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	JAK1 PHF3 MACF1 BOD1L1 XAF1 PRDM2	1.12e-06	200	75	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	BMP6 ZNF486 TPPP2 ZNF90 ZNF626	2.53e-06	128	75	5	c09c50efff794848c5d64bdc469ce17a3e77a8a1
ToppCell	COVID-19_Mild-PLT_0\|COVID-19_Mild / Disease Group and Platelet Clusters	ZFP64 CCDC138 MACF1 ZDHHC19 PDE11A	8.76e-06	165	75	5	083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 AMN1 ZNF185 CCDC138 PRDM4	1.01e-05	170	75	5	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 JAK1 DST USP24 MACF1	1.96e-05	195	75	5	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 DST DUOXA1 ZNF185 MACF1	2.01e-05	196	75	5	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	PPIG AMN1 PHF3 DHX29 COMMD3	2.01e-05	196	75	5	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRK LIPE ZNF81 ZNF841	2.19e-05	97	75	4	eab10b1af9cd0ce373cd4d0316e0d7b218630584
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRK LIPE ZNF81 ZNF841	2.19e-05	97	75	4	04f571708f2487b0dbd70ee507de6bf75be5f5d9
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PHF3 MACF1 BOD1L1 XAF1 PRDM2	2.21e-05	200	75	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	JAK1 PHF3 MACF1 BOD1L1 XAF1	2.21e-05	200	75	5	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	JAK1 CYP1A2 MTRR	4.00e-04	61	69	3	C1961102
Disease	Liver diseases	COL3A1 CYP1A2 SCO1	6.50e-04	72	69	3	C0023895
Disease	Liver Dysfunction	COL3A1 CYP1A2 SCO1	6.50e-04	72	69	3	C0086565
Disease	response to methotrexate, neurotoxicity	MACF1 ZDHHC19	8.98e-04	19	69	2	EFO_0011057, GO_0031427
Disease	Colorectal Carcinoma	COL3A1 CDKL5 CYP1A2 BMP6 MTRR XAF1 ZNF217	1.26e-03	702	69	7	C0009402
Disease	lobe attachment	HIVEP2 CCDC138 ZDHHC19 LNX1	1.42e-03	207	69	4	EFO_0007667
Disease	AIDS	CCRL2 LNX1	1.69e-03	26	69	2	EFO_0000765
Disease	vital capacity	ADAMTS19 BMP6 HIVEP2 DST FRMPD1 MIGA1 MED1 LNX1 PDE11A	2.28e-03	1236	69	9	EFO_0004312
Disease	Adult T-Cell Lymphoma/Leukemia	BMP6 VAV1	2.40e-03	31	69	2	C0023493
Disease	facial hair thickness measurement	MACF1 LNX1	2.55e-03	32	69	2	EFO_0007823
Disease	Complement deficiency disease	C5 C6	2.72e-03	33	69	2	C0272242
Disease	endometrial cancer (is_implicated_in)	JAK1 CYP1A2	3.23e-03	36	69	2	DOID:1380 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCKSSYNLDKSVHIT	CCRL2	271	O00421
GIKAVASSCSYLHEA	AMN1	106	Q8IY45
GKGCDRDTYSEKSLH	CLSTN1	311	O94985
IDTGRTKENKYHESS	DHX29	946	Q7Z478
KEKSSICYLSFPDSH	DENND6B	71	Q8NEG7
NGYLRHTESKISDCD	CDK5RAP2	746	Q96SN8
EGRKKAYSTCSTHLT	OR2L2	231	Q8NH16
EGRKKAYLTCSTHLT	OR2L3	231	Q8NG85
SSSCYLEEHVSKEAK	CYP1A2	156	P05177
EKVTEKSALHSHYCG	ADAMTS19	281	Q8TE59
ICDSSVSTHDLKVKY	JAK1	256	P23458
KVFGDSVCTGTHYKS	RADIL	66	Q96JH8
ESHTAVIYCKKDSGS	HCFC2	191	Q9Y5Z7
KYSCDRSSSIHKLED	DST	831	Q03001
YISCGEEHTAVLTKS	HERC3	246	Q15034
KLKCDYVSTSNGEHR	KIAA2026	511	Q5HYC2
HCISESDKYDLKTET	MTRR	36	Q9UBK8
KRSHDSDDSDYASSK	GPATCH8	906	Q9UKJ3
EGRKKAYSTCSTHLT	OR2L5	231	Q8NG80
EGRKKAYLTCSTHLT	OR2L8	231	Q8NGY9
LSYHATCSKAEVDKF	PDE11A	581	Q9HCR9
TSCKGASHYGLTKDR	LNX1	126	Q8TBB1
KRSSDSHKDLLSGLY	LRRFIP2	136	Q9Y608
QDSIKRKYSCDHNTS	MACF1	806	Q9UPN3
SRECDITKGKHSYNS	PPIG	546	Q13427
RKHLDEYASIASSSK	LPCAT2	361	Q7L5N7
SDSSEGKTKSVRHAY	BOD1L1	456	Q8NFC6
HRADKSTLSTYLEDC	COMMD3	76	Q9UBI1
SHYTKTSDGLCVKLG	FRK	191	P42685
VGSSLKYSDESKHCR	CCDC138	61	Q96M89
KYSDESKHCRTPLGS	CCDC138	66	Q96M89
SYTRSKSKDHEELSL	CPB2	321	Q96IY4
RLSSNSTKKESCGYD	C6	851	P13671
EAAKSTCERGYHDLS	FRMPD1	1536	Q5SYB0
HKTSTSEEVCSFYLK	C5	1366	P01031
SDYNSSELKTACRKH	BMP6	401	P22004
QETHYLADKLCSEKS	CNPY1	66	Q3B7I2
ITKTCHESYARSDTK	MAN1C1	481	Q9NR34
SKFTYTVLEDGCTKH	COL3A1	1406	P02461
TDREHGSKTSAKALY	EPS8	31	Q12929
SYRTKAKSHGALSDS	CDKL5	481	O76039
LSEASSTKAYCKEAH	DUOXA1	321	Q1HG43
SLTTHTGERKTDKDY	SCO1	141	O75880
KAESVVLEHRSYCSA	CHID1	56	Q9BWS9
DSTHVSCKLYKGLSD	MED1	471	Q15648
SKCVSAYAGAKTEDH	LIPE	781	Q05469
HILACASASDKKRYT	PRDM2	1351	Q13029
KECNSYTEFKAHLTS	PRDM4	551	Q9UKN5
SYCENHLGSTAKRIE	ORC3	481	Q9UBD5
YTKRAASDKGSSCSS	MIGA1	116	Q8NAN2
CGKTYATSSNLSRHK	SCRT1	196	Q9BWW7
CLAEGYGTKKTSKHA	NKRF	386	O15226
TDSVCYATTGLKVKH	PTPN14	1046	Q15678
SASLLDTDKRYCGKT	AATF	61	Q9NY61
TDTSKYTGTHKERFD	TPPP2	121	P59282
NCYGKDSISVHKEAS	ZNF562	156	Q6V9R5
GRYCSQVESASKHLD	VAV1	281	P15498
SKLELHESYCGSRTE	XAF1	96	Q6GPH4
VDEKTFLHYDCGSKT	RAET1G	56	Q6H3X3
GLSKHTTNDRTKYID	PHF3	806	Q92576
ECGKAFKYSSNLTTH	ZNF626	401	Q68DY1
DCGKAYTQRSSLTKH	ZNF841	541	Q6ZN19
ECGKAFTKSSTLTYH	ZNF708	396	P17019
TESKAYGSVIHKCED	ZBTB17	296	Q13105
DCGKELKYSSTLTAH	ZNF90	261	Q03938
DSVSLHKKFIADCYT	USP24	861	Q9UPU5
ECGKAYKESSHLTTH	ZNF493	281	Q6ZR52
ALSVSSADRTYKGKC	ZDHHC19	216	Q8WVZ1
GGKIKHLTSSRECSY	ZNF217	461	O75362
GKYLCAHKSVDTSAG	ZNF648	171	Q5T619
HSDGTRTCAKLYDKS	SYCN	31	Q0VAF6
GASGDKDHLYSTVCK	TGFB1I1	51	O43294
HSTFYSKSCVDDKQL	HIVEP2	2406	P31629
CGKAYTTSSNLTEHK	ZNF486	411	Q96H40
HLCDYAAVDSSSLKK	ZFP64	361	Q9NTW7
REHSYVLSAAKKSTG	ZNF185	191	O15231
HQKSHTGEKSYICAE	ZNF81	516	P51508