Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity IgG receptor activity

FCGR1A FCGR1BP

6.70e-0521642GO:0019771
GeneOntologyMolecularFunctionleukotriene receptor binding

FCGR1A FCGR1BP

6.70e-0521642GO:0031774
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NCOA3 ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZNF169 ZNF248 ZNF182 KMT2D SAMD11 RFXANK ZNF888 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417 HOMEZ

8.64e-05141216426GO:0000981
GeneOntologyMolecularFunctionG-quadruplex DNA binding

XRN1 NME2 PIF1

1.85e-04141643GO:0051880
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

ABCA7 LDLR LRP4

2.73e-0581653GO:0150094
GeneOntologyBiologicalProcesspositive regulation of apoptotic cell clearance

ABCA7 C4A C4B

2.73e-0581653GO:2000427
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

CFTR APOB LDLR FCGR1A FCGR1BP M6PR

4.22e-05791686GO:0030669
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

CFTR APOB LDLR FCGR1A FCGR1BP M6PR

1.66e-041011686GO:0045334
MousePhenoabnormal circulating HDL cholesterol level

DENND5B NCOA3 DYM NTRK2 APOB RFC1 ABCA7 LDLR SLC3A1 TYK2 ZNF182 ALMS1 BRD9 LTBP1

3.96e-0546012014MP:0000184
MousePhenoabnormal circulating lipoprotein level

DENND5B NCOA3 DYM NTRK2 APOB RFC1 ABCA7 LDLR SLC3A1 TYK2 TXNIP ZNF182 ALMS1 BRD9 LTBP1

5.07e-0553312015MP:0010330
MousePhenoabnormal lipoprotein level

DENND5B NCOA3 DYM NTRK2 APOB RFC1 ABCA7 LDLR SLC3A1 TYK2 TXNIP ZNF182 ALMS1 BRD9 LTBP1

5.07e-0553312015MP:0010329
DomainKRAB

ZNF573 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF169 ZNF248 ZNF182 ZNF552 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

1.65e-0835816317PS50805
DomainKRAB

ZNF573 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF169 ZNF248 ZNF182 ZNF552 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

1.65e-0835816317PF01352
DomainKRAB

ZNF573 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF169 ZNF248 ZNF182 ZNF552 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

2.57e-0836916317SM00349
DomainKRAB

ZNF573 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF169 ZNF248 ZNF182 ZNF552 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

2.67e-0837016317IPR001909
DomainZnf_C2H2-like

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 BRPF1 ZNF638 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

4.47e-0779616323IPR015880
Domain-

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

4.98e-07679163213.30.160.60
DomainZnf_C2H2

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 BRPF1 ZNF638 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

5.43e-0780516323IPR007087
DomainZnF_C2H2

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 BRPF1 ZNF638 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

5.79e-0780816323SM00355
Domainzf-C2H2

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

6.93e-0769316321PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

7.09e-0769416321IPR013087
DomainZINC_FINGER_C2H2_2

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 BRPF1 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

1.09e-0677516322PS50157
DomainZINC_FINGER_C2H2_1

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 BRPF1 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

1.14e-0677716322PS00028
Domainzf-C2H2_6

ZNF573 ZNF224 ZNF227 ZNF169 ZNF182 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

3.95e-0631416313PF13912
DomainABC_A

ABCA13 ABCA7 ABCA10

1.36e-04121633IPR026082
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.36e-04121633PF15371
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.36e-04121633IPR027970
DomainFYrich_C

KMT2D KMT2A

7.44e-0451632IPR003889
DomainFYrich_N

KMT2D KMT2A

7.44e-0451632IPR003888
DomainFYRC

KMT2D KMT2A

7.44e-0451632SM00542
DomainFYRN

KMT2D KMT2A

7.44e-0451632SM00541
DomainAnaphylatoxin_comp_syst

C4A C4B

7.44e-0451632IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

7.44e-0451632IPR001840
DomainRDM_domain_RFPL

RFPL4AL1 RFPL4A

7.44e-0451632IPR022723
DomainRDM

RFPL4AL1 RFPL4A

7.44e-0451632PF11002
DomainFYRN

KMT2D KMT2A

7.44e-0451632PF05964
DomainFYRC

KMT2D KMT2A

7.44e-0451632PF05965
DomainFYRC

KMT2D KMT2A

7.44e-0451632PS51543
DomainFYRN

KMT2D KMT2A

7.44e-0451632PS51542
DomainABC_tran

ABCA13 CFTR ABCA7 ABCA10

8.07e-04481634PF00005
DomainABC_TRANSPORTER_2

ABCA13 CFTR ABCA7 ABCA10

8.07e-04481634PS50893
DomainABC_TRANSPORTER_1

ABCA13 CFTR ABCA7 ABCA10

8.73e-04491634PS00211
DomainEPHD

KMT2D BRPF1 KMT2A

8.90e-04221633PS51805
DomainEGF_CA

LDLR THBS2 HMCN1 LRP4 LTBP1

9.38e-04861635PF07645
DomainABC_transporter-like

ABCA13 CFTR ABCA7 ABCA10

9.42e-04501634IPR003439
DomainDCX

DCLK2 DCLK1

1.11e-0361632SM00537
DomaincEGF

HMCN1 LRP4 LTBP1

1.46e-03261633PF12662
DomaincEGF

HMCN1 LRP4 LTBP1

1.46e-03261633IPR026823
DomainANATO

C4A C4B

1.54e-0371632SM00104
Domain-

DCLK2 DCLK1

1.54e-03716323.10.20.230
DomainANAPHYLATOXIN_2

C4A C4B

1.54e-0371632PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.54e-0371632PS01177
DomainANATO

C4A C4B

1.54e-0371632PF01821
DomainDCX

DCLK2 DCLK1

1.54e-0371632PF03607
DomainAnaphylatoxin/fibulin

C4A C4B

1.54e-0371632IPR000020
DomainAAA

DYNC2H1 ABCA13 CFTR RFC1 ABCA7 ABCA10

1.67e-031441636SM00382
DomainAAA+_ATPase

DYNC2H1 ABCA13 CFTR RFC1 ABCA7 ABCA10

1.67e-031441636IPR003593
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

2.05e-0381632IPR019565
DomainDC

DCLK2 DCLK1

2.05e-0381632PS50309
DomainThiol-ester_cl

C4A C4B

2.05e-0381632PF10569
DomainMacrogloblnA2_CS

C4A C4B

2.05e-0381632IPR019742
DomainDoublecortin_dom

DCLK2 DCLK1

2.05e-0381632IPR003533
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF573 ERCC3 ZNF274 ZNF875 MED14 PSMD7 ZNF224 ZNF226 ZNF227 ZNF169 ZNF248 CNOT6 TXNIP INTS14 KMT2D BRPF1 BANP MLH1 KMT2A ZNF552 ZNF420 ZNF749 ZNF468 ZNF782 ZNF418 ZNF417 AFF4

9.96e-06138711327M734
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CUL3 DLG5 ERCC3 MED14 PSMD7 ZNF226 RFC1 UBN2 F5 IPO9 ALMS1 XRN1 MED21 ZNF638 KMT2A CEP131 LTBP1 ARHGEF6

3.06e-096451691825281560
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DLG5 HIVEP1 PSMD7 CCDC88C IPO9 ALMS1 PIK3C2A TRIM9 SAMD11 XRN1 KMT2A ANKRD17 BOD1L1 CEP131 SH3BP5L DCLK2 TANC1 CRYBG3 DCLK1 WNK3

8.67e-098611692036931259
Pubmed

Human transcription factor protein interaction networks.

FLG NCOA3 HIVEP1 NUMA1 PSMD7 RFC1 UBN2 RNF214 KMT2D ALMS1 TRIM9 SAMD11 RFXANK BANP NIP7 BRD9 XRN1 ZNF638 KMT2A ANKRD17 ZNF420 CEP131 HAL NME2 HOMEZ

3.02e-0814291692535140242
Pubmed

Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

FCGR1A FCGR1BP C4A C4B

3.71e-088169416322460
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ERICH1 HIVEP1 NUMA1 ZNF226 RFC1 UBN2 RFXANK BRPF1 NIP7 BRD9 MLH1 SENP6 KMT2A BOD1L1 AFF4 HOMEZ

5.41e-086081691636089195
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOA3 HIVEP1 TXNIP KMT2D ALMS1 PPM1F XRN1 ANKRD17 CEP131 CRYBG3 NME2 HOMEZ KNL1

1.53e-074181691334709266
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MPP1 DLG5 HIVEP1 DYNC2H1 UBN2 TDRD3 ALMS1 BANP SENP6 CEP131 SH3BP5L TANC1 CRYBG3 NME2 KNL1

2.14e-075881691538580884
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

CUL3 RFC1 IPO9 PIK3C2A SBF2 XRN1 MLH1

2.38e-0787169717148452
Pubmed

The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.

FCGR1A FCGR1BP C4A C4B

2.58e-0712169431801071
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CUL3 NCOA3 HIVEP1 NUMA1 MED14 ZNF224 RFC1 KMT2D BRPF1 ZNF638 SENP6 KMT2A ANKRD17 KAT6B UNC5D ARHGEF6 HOMEZ

2.66e-077741691715302935
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CUL3 AMBRA1 PTK7 TYK2 XRN1 CARD6 MLH1 ZNF638 KMT2A ANKRD17 C4A C4B TANC1 CRYBG3 PLCE1

7.54e-076501691538777146
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA3 HIVEP1 MED14 UBN2 TNRC18 KMT2D MED21 KMT2A AFF4 KNL1

8.51e-072681691033640491
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DLG5 ERCC3 MAN2A1 SYNE1 MED14 UBN2 CNOT6 JARID2 TDRD3 WDR75 PIK3C2A NIP7 BRD9 XRN1 MLH1 KMT2A ANKRD17 CEP131 ISG20L2 TANC1 NME2 DCLK1 AFF4

1.09e-0614971692331527615
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO7A KIAA0319L MED14 AMBRA1 ABCA7 LDLR TYK2 CCDC88C TDRD3 TNRC18 KMT2D NADSYN1 SGSM2 SBF2 BANP LRP4 CEP131 SH3BP5L TANC1

2.03e-0611051691935748872
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOA3 HIVEP1 SYNE1 SPATA31D4 SPATA31D3 ALMS1 BANP NEURL4 TECPR1

2.30e-06233169937704626
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF274 ZNF227 ZNF182 ZNF552 ZNF749 ZNF84 ZNF468 ZNF417

3.15e-06181169837372979
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA3 HIVEP1 MYO7A DYNC2H1 ZNF227 RFC1 CSMD2 KMT2D IPO9 WDR75 PPM1F ANKRD17 FGD5 KNL1

3.20e-066381691431182584
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NUMA1 PSMD7 RFC1 TDRD3 ALMS1 TRIM9 MIF XRN1 MLH1 ZNF638 SENP6 KMT2A ANKRD17 BOD1L1 NME2 AFF4 KNL1

3.43e-069341691733916271
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DYM ZNF875 GRIK1 UBN2 ZNF248 TASOR2 PTK7 TYK2 TNRC18 NADSYN1 PTPRB SGSM2 SBF2 BANP ZNF638 ANKRD17 BOD1L1 DCLK2 TANC1 ZNF84 KAT6B AFF4

3.58e-0614891692228611215
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

AMBRA1 ABCA7 LDLR TYK2 INTS14 ALMS1 BRPF1 BRD9 XRN1 MLH1 LRP4 ANKRD17 TANC1 CRYBG3 KAT6B UNC5D AFF4 KNL1

9.19e-0611161691831753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CUL3 DLG5 AGAP5 AMBRA1 CNOT6 TRIM9 PPM1F SENP6 LRP4 ANKRD17 KAT6B HOMEZ

1.19e-055291691214621295
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TICRR MYO7A NEXMIF ZC2HC1C ST3GAL4 ZNF226 CSMD2 TDRD3 FRY TRIM9 TLR3 BOD1L1 PWWP3B PLXNB3

1.60e-057361691429676528
Pubmed

The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.

MPP1 CUL3 SYNE1

1.81e-0511169327621083
Pubmed

Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL.

TXNIP FCGR1A FCGR1BP

1.81e-0511169311252174
Pubmed

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

FCGR1A FCGR1BP

2.35e-052169228814603
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.35e-052169222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.35e-052169216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.35e-052169215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.35e-052169219062096
Pubmed

Comparison of apolipoprotein B metabolism in familial defective apolipoprotein B and heterogeneous familial hypercholesterolemia.

APOB LDLR

2.35e-052169211947895
Pubmed

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.

FCGR1A FCGR1BP

2.35e-052169237733444
Pubmed

Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation.

APOB LDLR

2.35e-052169214967814
Pubmed

[A genetic and clinical study in a family with familial hypercholesterolemia].

APOB LDLR

2.35e-052169221418831
Pubmed

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times.

APOB LDLR

2.35e-052169236709358
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.35e-052169219933335
Pubmed

Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine.

APOB LDLR

2.35e-052169235145523
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.35e-05216922459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.35e-052169217645767
Pubmed

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

FCGR1A FCGR1BP

2.35e-05216929257847
Pubmed

Common mutations of familial hypercholesterolemia patients in Taiwan: characteristics and implications of migrations from southeast China.

APOB LDLR

2.35e-052169222353362
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.35e-052169212207352
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.35e-052169227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.35e-052169222387014
Pubmed

Deletion of the murine ortholog of human 9p21.3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity.

APOB LDLR

2.35e-052169236950286
Pubmed

Impact of MIF gene promoter polymorphism on F508del cystic fibrosis patients.

CFTR MIF

2.35e-052169225503271
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.35e-052169223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.35e-052169223918728
Pubmed

LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population.

APOB LDLR

2.35e-052169217964958
Pubmed

Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A.

CFTR NME2

2.35e-052169226950439
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.35e-05216923037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.35e-052169211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.35e-05216924216347
Pubmed

Immunization of Chlamydia pneumoniae (Cpn)-infected Apob(tm2Sgy)Ldlr(tm1Her)/J mice with a combined peptide of Cpn significantly reduces atherosclerotic lesion development.

APOB LDLR

2.35e-052169224349031
Pubmed

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

FCGR1A FCGR1BP

2.35e-052169225231998
Pubmed

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.

FCGR1A FCGR1BP

2.35e-052169230190171
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.35e-05216926950384
Pubmed

Novel mutations identification in exon 4 of LDLR gene in patients with moderate hypercholesterolemia in a Venezuelan population.

APOB LDLR

2.35e-052169220019594
Pubmed

Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice.

APOB LDLR

2.35e-052169222100249
Pubmed

Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice.

APOB LDLR

2.35e-052169221357823
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.35e-05216928660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.35e-05216928428773
Pubmed

Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow.

APOB LDLR

2.35e-052169222268108
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.35e-052169224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.35e-052169221345967
Pubmed

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

FCGR1A FCGR1BP

2.35e-05216922136886
Pubmed

Characterization of the human nm23-H2 promoter region and localization of the microsatellite D17S396.

NME2P1 NME2

2.35e-05216927488060
Pubmed

Capillary Dynamics Regulate Post-Ischemic Muscle Damage and Regeneration in Experimental Hindlimb Ischemia.

APOB LDLR

2.35e-052169237626870
Pubmed

FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.

FCGR1A FCGR1BP

2.35e-052169230552619
Pubmed

Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.

FCGR1A FCGR1BP

2.35e-052169235833115
Pubmed

Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.

APOB LDLR

2.35e-052169215637307
Pubmed

Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.

FCGR1A FCGR1BP

2.35e-052169215528358
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.35e-05216922572548
Pubmed

The complement component C4 of mammals.

C4A C4B

2.35e-05216922302180
Pubmed

Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).

KMT2A KNL1

2.35e-052169212618768
Pubmed

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions.

MPP1 DLG5

2.35e-052169215952887
Pubmed

Immunization with a combination of 2 peptides derived from the C5a receptor significantly reduces early atherosclerotic lesion in Ldlr(tm1Her) Apob(tm2Sgy) J mice.

APOB LDLR

2.35e-052169222837469
Pubmed

Hypercholesterolemia Induced Immune Response and Inflammation on Progression of Atherosclerosis in Apob(tm2Sgy) Ldlr(tm1Her)/J Mice.

APOB LDLR

2.35e-052169226178198
Pubmed

Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.

FCGR1A FCGR1BP

2.35e-052169214991835
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.35e-052169222151770
Pubmed

Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.

FCGR1A FCGR1BP

2.35e-05216921402657
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.35e-052169218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.35e-052169229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

2.35e-05216926589636
Pubmed

Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.

APOB LDLR

2.35e-052169219834103
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.35e-052169225339671
Pubmed

MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease.

LDLR MIF

2.35e-052169219478200
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.35e-052169217728371
Pubmed

Modulation of recombinant antigenic constructs containing multi-epitopes towards effective reduction of atherosclerotic lesion in B6;129S-Ldlr(tm1Her)Apob(tm2Sgy)/J mice.

APOB LDLR

2.35e-052169225830298
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.35e-05216926149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.35e-05216926149581
Pubmed

[Low density lipoprotein receptor gene mutations in patients with clinical diagnosis of familial hypercholesterolemia.].

APOB LDLR

2.35e-052169215477777
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.35e-052169212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.35e-05216923542363
Pubmed

Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.

KMT2D KMT2A

2.35e-052169226711341
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.35e-05216922387317
Pubmed

Impact of genetic defects on atherosclerosis in patients suspected of familial hypercholesterolaemia.

APOB LDLR

2.35e-052169211737238
Pubmed

Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.

APOB LDLR

2.35e-052169221372297
Pubmed

Early development of calcific aortic valve disease and left ventricular hypertrophy in a mouse model of combined dyslipidemia and type 2 diabetes mellitus.

APOB LDLR

2.35e-052169225231636
Pubmed

Mouse FcgammaRI: identification and functional characterization of five new alleles.

FCGR1A FCGR1BP

2.35e-052169210752630
Pubmed

Molecular genetic testing for familial hypercholesterolemia in the Netherlands: a stepwise screening strategy enhances the mutation detection rate.

APOB LDLR

2.35e-052169216792510
InteractionYWHAH interactions

CUL3 NCOA3 TICRR DLG5 HIVEP1 CFTR PSMD7 CRY1 CCDC88C IPO9 ALMS1 PIK3C2A SAMD11 XRN1 ZNF638 KMT2A ANKRD17 BOD1L1 CEP131 SH3BP5L DCLK2 TANC1 CRYBG3 DCLK1 WNK3 ARHGEF6 HOMEZ

2.70e-07110216427int:YWHAH
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF573 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 RFPL4AL1 RFPL4A ZNF888 ZNF552 ZNF420 ZNF749 ZNF468 ZNF418 ZNF417

3.85e-05119216915chr19q13
Cytoband9q21.32

SPATA31D4 SPATA31D1 SPATA31D3

4.55e-051916939q21.32
Cytoband19q13.43

ZNF552 ZNF749 ZNF418 ZNF417

3.11e-0487169419q13.43
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF573 HIVEP1 ZNF274 ZNF875 ZNF224 ZNF226 ZNF227 ZNF232 ZXDA ZNF169 ZNF248 ZNF182 ZNF888 ZNF552 ZSCAN2 ZNF420 ZNF749 ZNF84 ZNF468 ZNF782 ZNF418 ZNF417

2.43e-097181222228
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA7 ABCA10

1.03e-04141223805
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 TNRC18 KMT2D

6.19e-04251223775
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG RPTN

9.28e-04712221350
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.58e-03912221234
GeneFamilyDoublecortin superfamily

DCLK2 DCLK1

1.96e-031012221369
GeneFamilyPHD finger proteins

KMT2D BRPF1 KMT2A KAT6B

3.23e-0390122488
GeneFamilyLow density lipoprotein receptors

LDLR LRP4

3.36e-03131222634
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

MAN2A1 AVL9 ZXDA TASOR2 CNOT6 EXOC5 PIK3C2A SBF2 CRYBG3

5.09e-081931679abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DENND5B TICRR ZC2HC1C CENPP PTPRB CRYBG3 WNK3 PIF1

3.20e-0717416786c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AMBRA1 UBOX5 ZNF182 SGSM2 SBF2 CARD6 MLH1

2.69e-061621677ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

THEMIS2 DLG5 IFI44 TXNIP FCGR1A FCGR1BP XRN1

2.80e-061631677d005115aa1e1458b51de7eb719794617a4168608
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 CFTR APOB PKHD1L1 HMCN1 UNC5D PLCE1

6.23e-0618416772cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 CFTR APOB PKHD1L1 HMCN1 UNC5D PLCE1

6.23e-061841677ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 CFTR APOB PKHD1L1 HMCN1 UNC5D PLCE1

6.23e-0618416772b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NTRK2 COL6A5 ST3GAL4 THBS2 SERPINI1 TRIM9 LTBP1

7.42e-0618916774f9608b84d135268a17455661870c46ae8554a24
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SYNE1 NTRK2 CHST9 CFAP54 HRH1 CDH3

7.68e-0619016773fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 PIWIL1 PKHD1L1 PTPRB PIK3C2A PPM1F FGD5

8.80e-061941677ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCOA3 HIVEP1 RNF214 PRKG2 CRYBG3 ZNF782 KAT6B

9.09e-0619516771e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYNE1 NTRK2 CSMD2 LDLR LRP4 PRKG2 WNK3

1.04e-05199167719a97e27a4758e794ce7246d295e112b47931a48
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 COL6A5 ABCA10 THBS2 HMCN1 LTBP1 DCLK1

1.07e-05200167758b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF248 CCDC88C SLC9A2 ZNF84 ZNF782 UNC5D

2.12e-0514916764b44108c40376a6b73258df40d2424e68f991383
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIVEP1 MAN2A1 F5 WDR75 SGSM2 ANKRD17

4.02e-051671676ced6ed9b412739c6ced622523347c10295edbf53
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZC2HC1C GRIK1 PKHD1L1 C4B LTBP1 PLCE1

4.89e-051731676ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZC2HC1C GRIK1 PKHD1L1 C4B LTBP1 PLCE1

4.89e-0517316763725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP1 APOB SLC3A1 SLC9A2 PRKG2 SDCBP2

5.38e-0517616767622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB ALMS1 HMCN1 ZSCAN2 FGD5 TANC1

5.55e-0517716768ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 ABCA13 LDLR SGSM2 TANC1 AFF4

5.91e-0517916766e965e424eebef50f0202cff75f458be395cfca1
ToppCellMS-Treg-naive_CD4|MS / Condition, Cell_class and T cell subcluster

AMBRA1 F5 ZNF169 RNF214 BRPF1 CARD6

6.09e-0518016767ca083616926d98420fa11a6e5ebc981623f79ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 F5 FRY CFAP54 HRH1 PLCE1

6.28e-0518116765f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 F5 FRY CFAP54 HRH1 PLCE1

6.28e-051811676c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFI44 GRIK1 TXNIP THBS2 LRP4 TANC1

6.48e-0518216763cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFI44 GRIK1 TXNIP THBS2 LRP4 TANC1

6.48e-0518216765d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPP TLR3 AIM2 PIF1 HOMEZ KNL1

6.68e-051831676ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPP TLR3 AIM2 PIF1 HOMEZ KNL1

6.68e-051831676e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPP TLR3 AIM2 PIF1 HOMEZ KNL1

6.68e-051831676263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCDC88C PTPRB SAMD11 LRP4 LTBP1 DCLK1

6.68e-051831676e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SYNE1 CHST9 FRY HRH1 UNC5D

6.68e-051831676cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFI44 GRIK1 THBS2 LRP4 TANC1 PLCE1

7.09e-0518516762e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 F5 FRY CFAP54 HRH1 PLCE1

7.09e-05185167634fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFI44 GRIK1 THBS2 LRP4 TANC1 PLCE1

7.09e-0518516767aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRY1 THBS2 TRIM9 HRH1 LTBP1 DCLK2

7.09e-051851676e58a009aaf342be019a909747b1895d5987d4daf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 F5 FRY CFAP54 HRH1 PLCE1

7.09e-0518516768816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

F5 PTPRB HMCN1 FGD5 LTBP1 DCLK1

7.30e-0518616762d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

DENND5B NCOA3 PTK7 JARID2 TNRC18 LRP4

7.30e-051861676de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

F5 PTPRB HMCN1 FGD5 LTBP1 DCLK1

7.30e-05186167692092f11ecce22c14f244e42c499af0822977e6f
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DENND5B NCOA3 PTK7 JARID2 TNRC18 LRP4

7.30e-0518616760b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

MED14 CNOT6 ALMS1 HMCN1 PIK3C2A BOD1L1

7.30e-05186167603db813598b67b1e08f759758a1c2023396921fa
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

PKHD1L1 PTPRB HMCN1 PIK3C2A FGD5 PWWP3B

7.52e-0518716767876dcb4800c2e54874df3d933efb79307a64a97
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

TDRD3 PTPRB LRP4 TANC1 WNK3 ARHGEF6

7.52e-051871676f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

TDRD3 PTPRB LRP4 TANC1 WNK3 ARHGEF6

7.52e-051871676da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 SERPINI1 PTPRB FGD5 LTBP1 SDCBP2

7.75e-051881676ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

NCOA3 AVL9 JARID2 THBS2 ZSCAN2 LTBP1

7.75e-05188167614bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

NTRK2 ST3GAL4 JARID2 THBS2 BANP DCLK1

7.98e-0518916763922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

F5 PKHD1L1 PTPRB HMCN1 FGD5 PWWP3B

7.98e-0518916767346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

NTRK2 ST3GAL4 LDLR THBS2 BANP DCLK1

7.98e-051891676b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

F5 PTPRB HMCN1 SAMD11 FGD5 LTBP1

8.21e-051901676aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

F5 PTPRB HMCN1 FGD5 LTBP1 DCLK1

8.45e-0519116764b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

NCOA3 SYNE1 PKHD1L1 PTPRB PIK3C2A FGD5

8.45e-051911676c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIK1 SERPINI1 PTPRB FGD5 LTBP1 SDCBP2

8.45e-051911676b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

PKHD1L1 PTPRB HMCN1 PIK3C2A FGD5 PWWP3B

8.70e-051921676c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CFTR LDLR HMCN1 HRH1 TANC1 DCLK1

8.70e-051921676356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

PKHD1L1 PTPRB HMCN1 PIK3C2A FGD5 PWWP3B

8.95e-05193167601c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

PKHD1L1 PTPRB HMCN1 PIK3C2A FGD5 PWWP3B

8.95e-0519316762531266bc57339d4e2b22a88817008e32b8c1598
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

CSMD2 THBS2 HMCN1 LTBP1 DCLK2 DCLK1

9.21e-05194167603a269f75a481ea54aea8e6444605db8d6df493d
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

PKHD1L1 PTPRB HMCN1 PIK3C2A FGD5 PWWP3B

9.21e-051941676b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B PKHD1L1 FRY PTPRB PPM1F FGD5

9.21e-05194167633cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLG SYNE1 F5 SAMD11 HRH1 PLCE1

9.21e-0519416761374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA10 CRY1 THBS2 LTBP1 DCLK1 WNK3

9.47e-051951676ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 NTRK2 CSMD2 F5 HMCN1 LRP4

9.47e-051951676d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 NTRK2 CSMD2 F5 HMCN1 LRP4

9.47e-05195167619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ABCA13 MUC15 CHST9 CFAP54 DAW1

9.47e-0519516769651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 CSMD2 ABCA10 HMCN1 SAMD11 LTBP1

1.00e-0419716760dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

IFI44 TXNIP FCGR1A FCGR1BP XRN1 AIM2

1.00e-041971676c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

CSMD2 ABCA10 THBS2 HMCN1 LTBP1 DCLK1

1.00e-041971676fb847f2277609c31fffcdf49517243ce0684facf
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

NCOA3 SYNE1 PTPRB HMCN1 PIK3C2A FGD5

1.00e-041971676f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 IFI44 MIF XRN1 ZNF638 NME2

1.03e-0419816764c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA3 SYNE1 PKHD1L1 PTPRB PIK3C2A FGD5

1.03e-04198167692416e65a0dc1a4bf931833407620ea05d362f56
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A5 ABCA10 THBS2 SAMD11 LTBP1 DCLK1

1.06e-041991676fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NTRK2 ABCA10 THBS2 SAMD11 LTBP1 DCLK1

1.09e-0420016760b2614b8513693dd508c9003699049efd9abac52
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NTRK2 ABCA10 THBS2 SAMD11 LTBP1 DCLK1

1.09e-0420016768d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA10 THBS2 HMCN1 SAMD11 LTBP1 DCLK1

1.09e-0420016766e3d1ae0ef84d3075afa40129a41169996462672
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 ABCA10 THBS2 HMCN1 LTBP1 DCLK1

1.09e-042001676b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

NTRK2 ABCA10 THBS2 SAMD11 LTBP1 DCLK1

1.09e-042001676c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

DLG5 DYNC2H1 SYNE1 RNF214 KMT2D

1.56e-041351675ac20133d4a36f48338b45bffb13e842cb66f83ad
ComputationalNeighborhood of MLL

ZNF274 NUMA1 CNOT6 EXOC5 IPO9 BRD9 KMT2A BOD1L1 ZNF84 KAT6B

1.79e-061749010GCM_MLL
DiseaseColorectal Carcinoma

ERICH1 ABCA13 SYNE1 CFTR APOB ZNF232 F5 ABCA10 SPACA7 PPM1F MLH1 HRH1 NME2 SDCBP2 DCLK1

4.79e-0670215515C0009402
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 KMT2D PLCE1

2.27e-05111553DOID:3717 (is_implicated_in)
Diseasedyslexia (implicated_via_orthology)

DCLK2 DCLK1

2.74e-0521552DOID:4428 (implicated_via_orthology)
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

APOB LDLR ANKRD17

4.96e-05141553EFO_0004611, EFO_0008589
Diseaseconcentration of large LDL particles measurement

APOB ST3GAL4 LDLR ABCA10

8.44e-05441554EFO_0022160
Diseasecholesterol in medium VLDL measurement

APOB ST3GAL4 LDLR ABCA10

8.44e-05441554EFO_0022225
Diseasefree cholesterol in small VLDL measurement

APOB ST3GAL4 LDLR ABCA10

1.10e-04471554EFO_0022272
Diseasefree cholesterol in medium VLDL measurement

APOB ST3GAL4 LDLR ABCA10

1.10e-04471554EFO_0022269
Diseasephospholipids in IDL measurement

APOB ST3GAL4 LDLR ABCA10

1.63e-04521554EFO_0022164
Diseasecholesterol in small VLDL measurement

APOB ST3GAL4 LDLR ABCA10

1.76e-04531554EFO_0022228
DiseaseCerebellar Ataxia

SYNE1 RFC1

2.71e-0451552C0007758
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

APOB LDLR ANKRD17

3.38e-04261553OBA_2045194
Diseasequality of life during menstruation measurement, breast pressure measurement

ANKRD17 DCLK2

4.06e-0461552EFO_0009366, EFO_0009393
DiseaseMalignant neoplasm of breast

THEMIS2 NCOA3 ERCC3 DYNC2H1 SYNE1 MED14 SLC9A2 KMT2D PPM1F DAW1 MIF NIP7 BOD1L1 FGD5 KAT6B

5.59e-04107415515C0006142
DiseaseLDL cholesterol change measurement

APOB LDLR

5.66e-0471552EFO_0007804
DiseaseColorectal Neoplasms

ABCA13 SYNE1 CFTR ABCA10 MLH1 NME2 DCLK1

6.80e-042771557C0009404
DiseaseFamilial hypercholesterolemia

APOB LDLR

7.52e-0481552cv:C0020445
DiseaseRhinitis

CFTR HRH1

7.52e-0481552C0035455
Diseasesarcoma (is_implicated_in)

PTPRB KNL1

7.52e-0481552DOID:1115 (is_implicated_in)
Diseasefactor VIII measurement, venous thromboembolism

ST3GAL4 F5 LRP4

7.55e-04341553EFO_0004286, EFO_0004630
DiseaseSchizophrenia

DYM ABCA13 NTRK2 AMBRA1 GRIK1 CSMD2 JARID2 SERPINI1 TLR3 HRH1 KMT2A DCLK1 WNK3

8.14e-0488315513C0036341
Diseasefree cholesterol to total lipids in large VLDL percentage

APOB ST3GAL4 LDLR

9.69e-04371553EFO_0022281
Diseasetriglycerides to total lipids in large VLDL percentage

APOB ST3GAL4 LDLR

1.13e-03391553EFO_0022332
Diseaseintermediate density lipoprotein measurement

APOB ST3GAL4 LDLR ABCA10

1.16e-03871554EFO_0008595
Diseasefamilial hypercholesterolemia (is_implicated_in)

APOB LDLR

1.20e-03101552DOID:13810 (is_implicated_in)
Diseasecholesterol in very small VLDL measurement

APOB LDLR ABCA10

1.22e-03401553EFO_0022231
Diseasefree cholesterol in medium LDL measurement

APOB ST3GAL4 LDLR

1.22e-03401553EFO_0022268
Diseaseautistic disorder (is_implicated_in)

NTRK2 JARID2 C4B

1.40e-03421553DOID:12849 (is_implicated_in)
Diseaseinterleukin 1 receptor-like 1 measurement

ST3GAL4 SLC9A2

1.46e-03111552EFO_0008168
Diseaseurokinase-type plasminogen activator measurement

CHST9 ST3GAL4

1.46e-03111552EFO_0010803
Diseaseprostatic hypertrophy (is_marker_for)

CFTR NME2

1.46e-03111552DOID:11132 (is_marker_for)
DiseaseNeurodevelopmental Disorders

CUL3 NEXMIF PTK7 KMT2A

1.49e-03931554C1535926
Diseasesystemic lupus erythematosus (implicated_via_orthology)

MAN2A1 C4A C4B

1.50e-03431553DOID:9074 (implicated_via_orthology)
DiseaseAdenocarcinoma of large intestine

PTK7 TYK2 MLH1 PRKG2

1.67e-03961554C1319315
Diseasetotal lipids in very small VLDL measurement

APOB LDLR ABCA10

1.72e-03451553EFO_0022156
Diseasetotal lipids in small LDL

APOB ST3GAL4 LDLR

1.95e-03471553EFO_0022168
Diseasefree cholesterol in very small VLDL measurement

APOB LDLR ABCA10

1.95e-03471553EFO_0022275
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

SYNE1 IFI44 GRIK1 KMT2A

2.01e-031011554EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseasecolon carcinoma (is_marker_for)

KMT2D TLR3

2.06e-03131552DOID:1520 (is_marker_for)
DiseaseHyperlipoproteinemia Type IIb

APOB LDLR

2.06e-03131552C1704417
Diseasephospholipids in medium LDL measurement

APOB ST3GAL4 LDLR

2.19e-03491553EFO_0022183
Diseaseapolipoprotein B to apolipoprotein A1 ratio

APOB ST3GAL4 LDLR

2.19e-03491553EFO_0021897
Diseasecholesterol in medium LDL measurement

APOB ST3GAL4 LDLR

2.19e-03491553EFO_0022224
Diseasecholesterol in small LDL measurement

APOB ST3GAL4 LDLR

2.19e-03491553EFO_0022227
Diseasecholesteryl esters to total lipids in small VLDL percentage

APOB ST3GAL4 LDLR

2.19e-03491553EFO_0022256
Diseasefree cholesterol in LDL measurement

APOB ST3GAL4 LDLR

2.33e-03501553EFO_0022266
Diseasefree cholesterol in large LDL measurement

APOB ST3GAL4 LDLR

2.46e-03511553EFO_0022176
Diseasephospholipids in very small VLDL measurement

APOB LDLR ABCA10

2.46e-03511553EFO_0022300
Diseasefree cholesterol to total lipids in small HDL percentage

APOB LDLR RNF214

2.46e-03511553EFO_0022285
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

APOB ST3GAL4 LDLR SENP6

2.49e-031071554EFO_0004614, EFO_0004615
Diseaseremnant cholesterol measurement

APOB ST3GAL4 LDLR ABCA10

2.57e-031081554EFO_0010815
Diseasephospholipids in medium VLDL measurement

APOB ST3GAL4 LDLR

2.60e-03521553EFO_0022154
Diseasetotal lipids in medium LDL

APOB ST3GAL4 LDLR

2.60e-03521553EFO_0022180
Diseasetotal lipids in LDL measurement

APOB ST3GAL4 LDLR

2.60e-03521553EFO_0022308
Diseasephospholipids in large LDL measurement

APOB ST3GAL4 LDLR

2.75e-03531553EFO_0022174
Diseasefree cholesterol in small LDL measurement

APOB ST3GAL4 LDLR

2.75e-03531553EFO_0022271
Diseaseresponse to statin, LDL cholesterol change measurement

APOB LDLR

2.75e-03151552EFO_0007804, GO_0036273
Diseasepulse pressure measurement

DYNC2H1 ZC2HC1C ST3GAL4 CENPP AREL1 THBS2 PIK3C2A SBF2 MIF ZNF638 HRH1 FGD5 LTBP1 PIF1 HOMEZ PLCE1

2.77e-03139215516EFO_0005763
Diseasefree cholesterol measurement

APOB ST3GAL4 LDLR ABCA10

3.03e-031131554EFO_0008591
Diseaseteratocarcinoma-derived growth factor 1 measurement

NTRK2 KMT2A

3.13e-03161552EFO_0008297
DiseaseHyperlipoproteinemia Type IIa

APOB LDLR

3.13e-03161552C0745103
Diseaselevel of Sterol ester (27:1/18:1) in blood serum

LDLR ANKRD17

3.13e-03161552OBA_2045195
Diseaselifestyle measurement, alcohol consumption measurement

CSMD2 CFAP54 HRH1 UNC5D

3.22e-031151554EFO_0007878, EFO_0010724
DiseaseCarcinoma, Granular Cell

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0205644
DiseaseAdenocarcinoma, Tubular

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0205645
DiseaseAdenocarcinoma, Oxyphilic

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0205642
DiseaseCarcinoma, Cribriform

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0205643
DiseaseAdenocarcinoma, Basal Cell

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0205641
DiseaseAdenocarcinoma

MPP1 NCOA3 KMT2A PLCE1

3.33e-031161554C0001418
Diseasetotal lipids in large LDL

APOB ST3GAL4 LDLR

3.38e-03571553EFO_0022163
Diseasecholesterol in large LDL measurement

APOB ST3GAL4 LDLR

3.38e-03571553EFO_0021901
DiseaseMultiple congenital anomalies

NADSYN1 AFF4

3.54e-03171552C0000772
DiseaseLipidemias

APOB LDLR

3.54e-03171552C1706412
DiseaseHyperlipidemia

APOB LDLR

3.54e-03171552C0020473
Diseasecholesterol in IDL measurement

APOB ST3GAL4 LDLR

3.55e-03581553EFO_0021899
Diseasephospholipids in LDL measurement

APOB ST3GAL4 LDLR

3.55e-03581553EFO_0022294
Diseasephospholipids in small LDL measurement

APOB ST3GAL4 LDLR

3.73e-03591553EFO_0022297
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

APOB ST3GAL4 LDLR NIP7

3.75e-031201554EFO_0004611, EFO_0004639
Diseasephospholipids in small VLDL measurement

APOB ST3GAL4 LDLR

3.91e-03601553EFO_0022146
Diseasetotal lipids in IDL

APOB ST3GAL4 LDLR

3.91e-03601553EFO_0022161
Diseaseglucuronate measurement

CHST9 DCLK1

3.97e-03181552EFO_0010486
Diseaselevel of Sphingomyelin (d34:1) in blood serum

LDLR ANKRD17

3.97e-03181552OBA_2045175
DiseaseHypercholesterolemia, Familial

APOB LDLR

3.97e-03181552C0020445
Diseasefree cholesterol in IDL measurement

APOB ST3GAL4 LDLR

4.09e-03611553EFO_0022181
Diseasemetabolic syndrome

APOB ST3GAL4 LDLR KMT2A DCLK2

4.19e-032001555EFO_0000195
Diseaseangina pectoris

DYNC2H1 APOB LDLR IPO9

4.34e-031251554EFO_0003913
Diseaseanorectal malformation

CSMD2 THBS2

4.42e-03191552MONDO_0019938
Diseasesodium-coupled monocarboxylate transporter 1 measurement

APOB LDLR

4.42e-03191552EFO_0802076
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

DYNC2H1 APOB LDLR

4.48e-03631553EFO_0001645, EFO_0004792
Diseaseesterified cholesterol measurement

APOB ST3GAL4 LDLR ANKRD17

4.72e-031281554EFO_0008589
Diseaselow density lipoprotein cholesterol measurement, physical activity

APOB ST3GAL4 LDLR

5.11e-03661553EFO_0003940, EFO_0004611

Protein segments in the cluster

PeptideGeneStartEntry
HREVQAVSNLSGQGK

BANP

261

Q8N9N5
SLLQEKSQRQHTDGT

ERICH1

141

Q86X53
SNQRSLKVQALHSLG

CFAP54

1911

Q96N23
NFQQGHGSSTRKDSI

ARHGEF6

671

Q15052
SVNQGQNIHRKTTAS

CFTR

776

P13569
QKTSVLTQVGVSQGH

CSMD2

326

Q7Z408
SQTKLVNGQSHISLS

C4B

301

P0C0L5
QNNVLVESHSGRGKT

CRYBG3

821

Q68DQ2
QITAILGHNGAGKST

ABCA10

421

Q8WWZ4
ILQESARKLNTQGSH

SH3BP5L

91

Q7L8J4
QITGGDHSRTLFQLK

BRD9

446

Q9H8M2
ATGKLHTANRIQVAT

AIM2

36

O14862
GLTGHITFNKTNGLR

GRIK1

371

P39086
LETTTGQHTDTLNQK

ALMS1

526

Q8TCU4
TQHQHKQTRALSGGL

ABCA13

3966

Q86UQ4
GKAGLRQQSHQESTR

FLG

441

P20930
GSSQNNSGSIRHELQ

AMBRA1

486

Q9C0C7
LAGSHGKRNNTITTT

ANKRD17

1551

O75179
STLTGINIRNHSKQT

CENPP

71

Q6IPU0
RSVLTQTKHSLAGNG

CIRBP-AS1

26

Q8TBR5
SKQSVQTRHLSGGMQ

ABCA7

931

Q8IZY2
QKRSSGLQSGHSSQR

AFF4

121

Q9UHB7
GISHSQRLQTQIASK

KAT6B

1906

Q8WYB5
QVGRNIIHGSDSVKS

NME2

111

P22392
SNLTILKTNISHNGT

FCGR1BP

151

Q92637
SVHLNLGQKGNRKTS

PTPRB

1666

P23467
SLLSGSHGKENQDIN

MUC15

16

Q8N387
LRTIQSKVGNGHSNE

MAN2A1

1051

Q16706
AVSVHQKLRGNSTLT

SBF2

1241

Q86WG5
GLGKGALTHSIQTSQ

ERVFC1-1

431

P60608
TQHSKVNDSNELGGL

KIAA0319L

201

Q8IZA0
STRQSKSSLSGQHGR

GARIN4

396

Q8IYT1
KSSLSGQHGRERTQA

GARIN4

401

Q8IYT1
LRKQRSSQHGGSSTS

DCLK1

341

O15075
LKQISAHGRSSSNVN

DCLK2

351

Q8N568
LNLKGSSEQLHGRSE

CCDC88C

1586

Q9P219
TIRGQHLQTGGNTSA

PLXNB3

946

Q9ULL4
ETQSGGGSRLQVHQK

LTBP1

146

Q14766
IRTTQLAKAQGHISQ

PIK3C2A

341

O00443
FEQSVQGGSQTAKHR

FGD5

1021

Q6ZNL6
QGNHLLTGSSDKTAR

DAW1

356

Q8N136
HINLSGQKDSGISLE

DLG5

721

Q8TDM6
LNRDIQVGKSGHSSV

ISG20L2

311

Q9H9L3
AQSQLKTRSGTHSQS

MED21

126

Q13503
QELGKTNLEHTTGQL

KNL1

806

Q8NG31
SLHSIGKIGGAQNRS

MIF

61

P14174
SVNRQGKIVLSSEHG

RFPL4A

171

A6NLU0
GHSGNLTTDALRNKV

PRKG2

16

Q13237
GSKLQIARSQHSDSG

HMCN1

3206

Q96RW7
NQQVLGRKTGTASVH

MED14

341

O60244
GSKQHGITLQRRSES

BOD1L1

856

Q8NFC6
SGNLLRQLNKSGTTQ

DYNC2H1

1876

Q8NCM8
SKNHQKRSIGTGGIQ

EXOC5

371

O00471
INSGAHKATLRIGQD

APOB

1636

P04114
LQVNLVRSHSSGVGK

HAL

186

P42357
HQALVGTNTTGISEK

IFI44

216

Q8TCB0
GEGQQRHSQLKSSSK

CARD6

681

Q9BX69
HNKVLEQATQSLRGS

DYM

496

Q7RTS9
HSVQNSERGKKIGNV

AVL9

581

Q8NBF6
QVTGSNTRKHILQVS

CUL3

581

Q13618
GSLQIGKALQEAHRT

COL6A5

106

A8TX70
IGRGSLRHSLATQNQ

INTS14

121

Q96SY0
HGDSQQTHLLKQGRS

CRY1

541

Q16526
NLGKLTTVQIGHDNS

DENND5B

986

Q6ZUT9
TTVQIGHDNSGLLAK

DENND5B

991

Q6ZUT9
IRSLHKNIGGSETFQ

AREL1

426

O15033
SNLTILKTNISHNGT

FCGR1A

151

P12314
TRHLQEAEQTKNSGT

IPO9

426

Q96P70
HSLTQSGESAEKNQR

KMT2A

801

Q03164
HNTTSRELNVSKIGS

KMT2A

2336

Q03164
NQLLASKTGIHSSQR

KMT2A

3456

Q03164
SGVGRSHIKNALLSQ

MPP1

291

Q00013
NVLIQISSHGGSRRQ

ERCC3

621

P19447
NKIRNSELIANGSSH

FRY

711

Q5TBA9
RSHGQLKTDEQGLNT

HRH1

326

P35367
QHLQSSGLSKEQAGR

HOMEZ

221

Q8IX15
QRSGEGTLLDLHQQK

CEP131

306

Q9UPN4
THPESNQGILTTRKG

CDH3

381

P22223
GTTNGRITHGFKLQS

CNOT6

456

Q9ULM6
QEGDHIGLTRKSNSA

NEURL4

431

Q96JN8
SQTKLVNGQSHISLS

C4A

301

P0C0L4
QSHLTRQQGSGLRVA

PPM1F

376

P49593
SQGLRHQVEQLSSSL

NUMA1

546

Q14980
SLKHSTTLTNRQRGN

RFXANK

66

O14593
RQHAEGIAGSLKTVN

JARID2

46

Q92833
ELGAQGSTQKEIRHS

SERPINI1

61

Q99574
SFSGRILQTEKIHQG

PIWIL1

451

Q96J94
QLQATASHKVGRDGI

PIF1

406

Q9H611
SVNRQGKIELSSEHG

RFPL4AL1

171

F8VTS6
RGQLQHLGTRGSNTS

UBOX5

451

O94941
GRSSGNIFHKEQQRT

SPACA7

171

Q96KW9
QRSLSKHNRSNIGTE

TDRD3

71

Q9H7E2
SSQSGGAKRQSIHLE

SYNE1

6366

Q8NF91
RHLIGKNSVLNSSTA

F5

811

P12259
ALGHSIQQRATSTAK

CCDC51

66

Q96ER9
TENHLLAIVNGTKGS

PWWP3B

566

Q5H9M0
RSGETSHTISQLNKL

PLCE1

46

Q9P212
KENGRSTNSHLGTSN

RFC1

126

P35251
TLSQRITNQVHGLKG

PSMD7

186

P51665
QVGRNIIHGSDSVKS

NME2P1

96

O60361
INSGSQGATKNHRSI

NEXMIF

1381

Q5QGS0
NHVLKSGLGRITENT

NIP7

111

Q9Y221
TQKGNLGSSSLQGHL

MARCOL

181

A0A1B0GUY1
SISSNGSHLGTKQQV

NCOA3

816

Q9Y6Q9
HQQKSGGTLVLVSQD

SGSM2

331

O43147
GSGHNVSQEALAIKR

ST3GAL4

306

Q11206
TDNLKHSTRGILGSQ

SLC3A1

41

Q07837
AQIVKTSQHLGSGQS

TANC1

1531

Q9C0D5
SSTAGQRRKQGLAQH

SAMD11

261

Q96NU1
RGQSLHLTQVKSLAQ

SPATA31D4

566

Q6ZUB0
VQQHIESKLLGSNSS

MLH1

326

P40692
GGQHVNKTDSAVRLV

MTRF1

311

O75570
VKGSSAARNGLLTNH

SDCBP2

216

Q9H190
LQHRSKVQGEQSSET

BRPF1

1196

P55201
VSTVHITKNRNGGGS

AGAP5

196

A6NIR3
RLLTKTSHSQGGDQA

CHST9

106

Q7L1S5
SGGRIHNLKTQLFSQ

C12orf54

106

Q6X4T0
NETSHTQGSLRITNI

NTRK2

241

Q16620
NSHIQLVRNGAKLSS

RNF214

416

Q8ND24
DQERSLSLSNVKGHG

TNRC18

706

O15417
RGQSLHLTQVKSLAQ

SPATA31D3

566

P0C874
QKSNLGVHQRTHSGE

ZNF182

441

P17025
LLQQGLQRSSQIHTS

UBN2

876

Q6ZU65
HNGLSSTKLGTQVQL

TLR3

156

O15455
QKRHTQAGEGTSLET

TICRR

1176

Q7Z2Z1
KSFGNRSSLNTHQGI

ZSCAN2

341

Q7Z7L9
CNTGQRQKTHTGERS

ZNF749

736

O43361
TGSNLIQHRKTHTGE

ZNF573

481

Q86YE8
SNGKETVVGRLNETH

M6PR

96

P20645
HSREKGTQTSGLLQQ

SLC9A2

751

Q9UBY0
SNTGLGEDIIHQLSK

WDR75

796

Q8IWA0
HLSGNDSGVRLGQKQ

SPATA31D1

811

Q6ZQQ2
VIANKVQGSHSLSRG

TECPR1

1091

Q7Z6L1
GKGFVQSSSLTQHQR

ZNF274

541

Q96GC6
KNQGLSKQRRHSSEG

THEMIS2

556

Q5TEJ8
GVKSSQVLGLQQHAR

THEMIS2

571

Q5TEJ8
SQKGSLISHQRVHTG

ZNF417

306

Q8TAU3
NLSHGSRSETGNQKL

XRN1

1171

Q8IZH2
LLRTSIHQNSGGQKS

SENP6

251

Q9GZR1
HSTGNIFRITNNGKD

PKHD1L1

1386

Q86WI1
GRTHTKLSNISESQL

UNC5D

926

Q6UXZ4
EQGDSSQQSLKGHLR

ZC2HC1C

36

Q53FD0
SQKSQLNTHQRIHTG

ZNF84

581

P51523
NSHTNRTEGGITKGA

TRIM9

631

Q9C026
GKGFTLSSNLQAHQR

ZNF226

481

Q9NYT6
GKGNTEVIHTGTLQR

ZNF888

61

P0CJ79
HGSQKERNLITVTGS

ZXDA

781

P98168
RSGLLQQEATHTGKS

ZNF552

181

Q9H707
SRKGNLIQHQRSHTG

ZNF418

436

Q8TF45
GKGFSQSSKLQTHQR

ZNF227

526

Q86WZ6
SSNLGQHQRIHTGEK

ZNF232

316

Q9UNY5
GKSFIRGSQLTQHQR

ZNF420

481

Q8TAQ5
QTKTGTLQDLIQHGS

TASOR2

1011

Q5VWN6
QKSNLRGHQRTHTGE

ZNF782

601

Q6ZMW2
GRGFNDKSTLISHQR

ZNF875

531

P10072
KVVNSTTGTGEHLRN

THBS2

1066

P35442
GRRQKQNLGHFTSDT

TMEFF1

361

Q8IYR6
AGLSVIHTRQKSSQG

ZNF224

136

Q9NZL3
GQSERHTQQSETLGQ

RPTN

241

Q6XPR3
TQKLSSVRGNHIISG

TXNIP

231

Q9H3M7
DGQSNHTVSSKERNL

PTK7

171

Q13308
KTLSSTGQGNTEVIH

ZNF468

56

Q5VIY5
GGVSRLETNENSHQK

HIVEP1

611

P15822
VINSSNVHVGSRGSK

ZNF638

356

Q14966
QGLGQKSHLISDQRT

ZNF169

521

Q14929
HNNKTVSVENGDRGS

ZNF248

106

Q8NDW4
LQSTSGSQRHMVGQK

TLE6

486

Q9H808
QKEITQLSHLGQGTR

TYK2

586

P29597
QSLTHVDNGIVATGK

WNK3

1601

Q9BYP7
KAQGGQTIRSVAEQH

KMT2D

351

O14686
KLHSISSIDVNGGNR

LDLR

581

P01130
QTRSIHRADKGTGSN

LRP4

1271

O75096
ITNASGSHQVLRKAN

NADSYN1

196

Q6IA69
VTKRLHDGESTVQGN

MYO7A

1126

Q13402