Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF13B MYH1 MYO9B DNAH2 KIF20B DNAH14 STARD9 DYNLRB1	9.56e-06	118	175	8	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	KIF13B DNAH2 KIF20B DNAH14 STARD9 DYNLRB1	3.43e-05	70	175	6	GO:0003777
Domain	DUF3480	ZFYVE16 ZFYVE9	8.04e-05	2	168	2	PF11979
Domain	DUF3480	ZFYVE16 ZFYVE9	8.04e-05	2	168	2	IPR022557
Domain	Znf_FYVE_endofin	ZFYVE16 ZFYVE9	8.04e-05	2	168	2	IPR017165
Domain	VWA	CACHD1 ITGAE ITIH2 COL14A1 CACNA2D3	1.46e-04	56	168	5	PF00092
Domain	VWF_A	CACHD1 ITGAE ITIH2 COL14A1 SEC23A CACNA2D3	2.72e-04	99	168	6	IPR002035
Domain	Laminin_N	LAMA1 LAMB3 USH2A	3.67e-04	16	168	3	IPR008211
Domain	LamNT	LAMA1 LAMB3 USH2A	3.67e-04	16	168	3	SM00136
Domain	LAMININ_NTER	LAMA1 LAMB3 USH2A	3.67e-04	16	168	3	PS51117
Domain	Laminin_N	LAMA1 LAMB3 USH2A	3.67e-04	16	168	3	PF00055
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	4.77e-04	4	168	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	4.77e-04	4	168	2	PF01557
Domain	-	FAHD2B FAHD2A	4.77e-04	4	168	2	3.90.850.10
Domain	-	CACHD1 ITIH2 COL14A1 SEC23A CACNA2D3	5.42e-04	74	168	5	3.40.50.410
Domain	VWA_N	CACHD1 CACNA2D3	7.90e-04	5	168	2	IPR013608
Domain	VWA_N	CACHD1 CACNA2D3	7.90e-04	5	168	2	PF08399
Domain	NFAT	NFATC4 NFAT5	7.90e-04	5	168	2	IPR008366
Domain	VWFA	CACHD1 ITGAE ITIH2 COL14A1 CACNA2D3	8.66e-04	82	168	5	PS50234
Domain	VWA	CACHD1 ITGAE ITIH2 COL14A1 CACNA2D3	9.66e-04	84	168	5	SM00327
Domain	PKD	PMEL SORCS3	1.64e-03	7	168	2	PF00801
Domain	ERAP1-like_C_dom	ERAP1 ERAP2	2.17e-03	8	168	2	IPR024571
Domain	P_TREFOIL_1	MGAM ZP4	2.17e-03	8	168	2	PS00025
Domain	ERAP1_C	ERAP1 ERAP2	2.17e-03	8	168	2	PF11838
Domain	Trefoil	MGAM ZP4	2.17e-03	8	168	2	PF00088
Domain	P_trefoil_CS	MGAM ZP4	2.17e-03	8	168	2	IPR017957
Domain	FYVE	ZFYVE16 ZFYVE9 ZFYVE26	2.20e-03	29	168	3	PF01363
Domain	FYVE	ZFYVE16 ZFYVE9 ZFYVE26	2.20e-03	29	168	3	SM00064
Domain	EGF_LAM_2	LAMA1 LAMB3 USH2A	2.43e-03	30	168	3	PS50027
Domain	EGF_LAM_1	LAMA1 LAMB3 USH2A	2.43e-03	30	168	3	PS01248
Domain	FHA	KIF13B PHLDB1 STARD9	2.67e-03	31	168	3	PF00498
Domain	P_TREFOIL_2	MGAM ZP4	2.78e-03	9	168	2	PS51448
Domain	PD	MGAM ZP4	2.78e-03	9	168	2	SM00018
Domain	RHD_dimer	NFATC4 NFAT5	3.45e-03	10	168	2	IPR032397
Domain	RHD_dimer	NFATC4 NFAT5	3.45e-03	10	168	2	PF16179
Domain	REL_1	NFATC4 NFAT5	3.45e-03	10	168	2	PS01204
Domain	-	NFATC4 NFAT5	3.45e-03	10	168	2	2.60.40.340
Domain	NFkB/Dor	NFATC4 NFAT5	3.45e-03	10	168	2	IPR000451
Domain	RHD_DNA_bind_dom	NFATC4 NFAT5	3.45e-03	10	168	2	IPR011539
Domain	RHD_DNA_bind	NFATC4 NFAT5	3.45e-03	10	168	2	PF00554
Domain	REL_2	NFATC4 NFAT5	3.45e-03	10	168	2	PS50254
Domain	CENP-B_N	TIGD2 JRKL	3.45e-03	10	168	2	PF04218
Domain	Znf_FYVE-rel	ZFYVE16 ZFYVE9 ZFYVE26	3.49e-03	34	168	3	IPR017455
Domain	fn3	NRCAM ABI3BP TSPOAP1 COL14A1 MYOM2 USH2A	3.49e-03	162	168	6	PF00041
Domain	EGF_Lam	LAMA1 LAMB3 USH2A	3.79e-03	35	168	3	SM00180
Domain	Laminin_EGF	LAMA1 LAMB3 USH2A	3.79e-03	35	168	3	PF00053
Domain	-	KIF13B PHLDB1 STARD9	4.11e-03	36	168	3	2.60.200.20
Domain	FHA_dom	KIF13B PHLDB1 STARD9	4.11e-03	36	168	3	IPR000253
Domain	-	MGAM ZP4	4.19e-03	11	168	2	4.10.110.10
Domain	WH1	HOMER2 HOMER1	4.19e-03	11	168	2	SM00461
Domain	WH1/EVH1_dom	HOMER2 HOMER1	4.19e-03	11	168	2	IPR000697
Domain	PKD	PMEL SORCS3	4.19e-03	11	168	2	PS50093
Domain	WH1	HOMER2 HOMER1	4.19e-03	11	168	2	PF00568
Domain	PKD_dom	PMEL SORCS3	4.19e-03	11	168	2	IPR000601
Domain	-	PMEL SORCS3	4.19e-03	11	168	2	2.60.40.670
Domain	Znf_FYVE	ZFYVE16 ZFYVE9 ZFYVE26	4.79e-03	38	168	3	IPR000306
Domain	Laminin_EGF	LAMA1 LAMB3 USH2A	4.79e-03	38	168	3	IPR002049
Domain	P_trefoil_dom	MGAM ZP4	5.00e-03	12	168	2	IPR000519
Domain	HTH_Psq	TIGD2 JRKL	5.00e-03	12	168	2	IPR007889
Domain	HTH_PSQ	TIGD2 JRKL	5.00e-03	12	168	2	PS50960
Domain	CENPB	TIGD2 JRKL	5.00e-03	12	168	2	SM00674
Domain	Peptidase_M1	ERAP1 ERAP2	5.00e-03	12	168	2	IPR001930
Domain	DDE_1	TIGD2 JRKL	5.00e-03	12	168	2	PF03184
Domain	DDE_SF_endonuclease_dom	TIGD2 JRKL	5.00e-03	12	168	2	IPR004875
Domain	ZF_FYVE	ZFYVE16 ZFYVE9 ZFYVE26	5.53e-03	40	168	3	PS50178
Domain	HTH_CENPB	TIGD2 JRKL	5.88e-03	13	168	2	PS51253
Domain	HTH_Tnp_Tc5	TIGD2 JRKL	5.88e-03	13	168	2	PF03221
Domain	Peptidase_M1_N	ERAP1 ERAP2	5.88e-03	13	168	2	IPR014782
Domain	Peptidase_M1	ERAP1 ERAP2	5.88e-03	13	168	2	PF01433
Domain	WH1	HOMER2 HOMER1	5.88e-03	13	168	2	PS50229
Domain	HTH_CenpB_DNA-bd_dom	TIGD2 JRKL	5.88e-03	13	168	2	IPR006600
Domain	Thioredoxin	PDIA2 TXN2	5.88e-03	13	168	2	IPR005746
Domain	SET	SETD4 KMT2D SETD5	5.93e-03	41	168	3	PF00856
Domain	Kinesin_motor_CS	KIF13B KIF20B STARD9	5.93e-03	41	168	3	IPR019821
Domain	FN3	NRCAM ABI3BP TSPOAP1 COL14A1 MYOM2 USH2A	6.63e-03	185	168	6	SM00060
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH14	6.82e-03	14	168	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH14	6.82e-03	14	168	2	IPR024743
Domain	MT	DNAH2 DNAH14	6.82e-03	14	168	2	PF12777
Domain	AAA_8	DNAH2 DNAH14	6.82e-03	14	168	2	PF12780
Domain	-	KIF13B KIF20B STARD9	7.23e-03	44	168	3	3.40.850.10
Domain	Kinesin	KIF13B KIF20B STARD9	7.23e-03	44	168	3	PF00225
Domain	KISc	KIF13B KIF20B STARD9	7.23e-03	44	168	3	SM00129
Domain	KINESIN_MOTOR_1	KIF13B KIF20B STARD9	7.23e-03	44	168	3	PS00411
Domain	Kinesin_motor_dom	KIF13B KIF20B STARD9	7.23e-03	44	168	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF13B KIF20B STARD9	7.23e-03	44	168	3	PS50067
Domain	Cyt_P450_E_grp-I	CYP46A1 CYP4F12 CYP4F11	7.69e-03	45	168	3	IPR002401
Domain	DHC_fam	DNAH2 DNAH14	7.82e-03	15	168	2	IPR026983
Domain	Dynein_heavy	DNAH2 DNAH14	7.82e-03	15	168	2	PF03028
Domain	Dynein_heavy_dom	DNAH2 DNAH14	7.82e-03	15	168	2	IPR004273
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 FLNB DNAJC13 HIVEP1 ZBTB33 ZFYVE16 ICE1 INPP5F CHAMP1 KIF20B KMT2D BRCA2 BUB1B NAV1 CRYBG3 TP53BP2 EXOC4 NPAT	5.09e-12	418	175	18	34709266
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B CASP8AP2 KRT9 HIVEP1 MYO9B STXBP4 TOPBP1 EXOSC1 TTK KIF20B BRCA2 RECQL5 NAV1 CRYBG3 LRIF1 ZMYM6 EXOC4	8.68e-09	588	175	17	38580884
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF13B HIVEP1 TRIO STXBP4 INPP5F RFX7 TTK PIK3R4 FSIP2 PHLDB1 STARD9 BUB1B NAV1 CRYBG3 PEAK1 PPIP5K2 DMTN TP53BP2 AHNAK2 EXOC4	1.58e-08	861	175	20	36931259
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KIF13B DNAJC13 TBC1D9B TSPOAP1 ADGRV1 PHLDB1 N4BP1 CLUH	5.13e-08	102	175	8	9734811
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	NRCAM TOPBP1 CACHD1 CEMIP NAV1 LRP4 NFAT5 CLUH	3.37e-07	130	175	8	12421765
Pubmed	NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.	NFATC4 HOMER2 HOMER1	4.32e-06	7	175	3	18218901
Pubmed	High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.	ZBTB33 NAV1 RNF41 HOMER2 HOMER1	5.37e-06	50	175	5	29560723
Pubmed	Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy.	TAF1C SETD4 KMT2D TAMM41 COL14A1 HAGH PRR11	6.43e-06	137	175	7	30862715
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ZFYVE16 ZDHHC5 TTK N4BP1 CRYBG3 PEAK1 TP53BP2 AHNAK2 EXOC4	8.15e-06	263	175	9	34702444
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TRIO ZDHHC5 CACHD1 ERICH5 JPH1 PHLDB1 ZFYVE9 TAMM41 PEAK1 EXOC4 WDR48	1.04e-05	421	175	11	36976175
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TBC1D9B NRF1 TRIO MYO9B ZDHHC5 LAMB3 ICE1 SLC7A1 PHLDB1 THADA KMT2D SETD5 NAV1 LRP4 ZFYVE26 RIC1 AHNAK2 SYMPK	1.30e-05	1105	175	18	35748872
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	EXOSC1 RFX7 TTK PLBD2 KMT2D BUB1B	1.68e-05	106	175	6	31024071
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 DNAJC13 STXBP4 ZDHHC5 NFS1 TTK SRPRB JPH1 TXLNA THADA ERAP2 MRPS2 BUB1B COL14A1 CRYBG3 PEAK1 PRR11 CLUH FAM177A1 EXOC4 NPAT	2.06e-05	1487	175	21	33957083
Pubmed	ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.	ZDHHC11B ZDHHC11	2.52e-05	2	175	2	28331227
Pubmed	Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.	ERAP1 ERAP2	2.52e-05	2	175	2	18393273
Pubmed	Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.	APOB NPC1L1	2.52e-05	2	175	2	18031309
Pubmed	The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.	TTK BUB1B	2.52e-05	2	175	2	32284991
Pubmed	Antigenic peptide trimming by ER aminopeptidases--insights from structural studies.	ERAP1 ERAP2	2.52e-05	2	175	2	23545452
Pubmed	Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit.	TTK BUB1B	2.52e-05	2	175	2	19015317
Pubmed	No association of alcohol dependence with HOMER 1 and 2 genetic variants.	HOMER2 HOMER1	2.52e-05	2	175	2	20333726
Pubmed	Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.	ERAP1 ERAP2	2.52e-05	2	175	2	32321463
Pubmed	Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.	ERAP1 ERAP2	2.52e-05	2	175	2	30215709
Pubmed	The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues.	ERAP1 ERAP2	2.52e-05	2	175	2	12436110
Pubmed	An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides.	ERAP1 ERAP2	2.52e-05	2	175	2	12436109
Pubmed	ERAP1-ERAP2 haplotypes are associated with ankylosing spondylitis in Polish patients.	ERAP1 ERAP2	2.52e-05	2	175	2	30794838
Pubmed	Hypoxia-inducible factor-1alpha regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells.	HIF1A MMP1	2.52e-05	2	175	2	18588890
Pubmed	Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion.	HOMER2 HOMER1	2.52e-05	2	175	2	17553998
Pubmed	Reciprocal Homer1a and Homer2 Isoform Expression Is a Key Mechanism for Muscle Soleus Atrophy in Spaceflown Mice.	HOMER2 HOMER1	2.52e-05	2	175	2	35008503
Pubmed	Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection.	ERAP1 ERAP2	2.52e-05	2	175	2	20843824
Pubmed	Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.	BRCA2 BUB1B	2.52e-05	2	175	2	10749118
Pubmed	Roles of HIF-1α in a novel optical orthotopic spontaneous metastatic bladder cancer animal model.	HIF1A MMP1	2.52e-05	2	175	2	22341926
Pubmed	ERAP1-ERAP2 dimerization increases peptide-trimming efficiency.	ERAP1 ERAP2	2.52e-05	2	175	2	24928998
Pubmed	Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma.	ERAP1 ERAP2	2.52e-05	2	175	2	20419298
Pubmed	Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.	HOMER2 HOMER1	2.52e-05	2	175	2	16011574
Pubmed	Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA.	ZFYVE16 ZFYVE9	2.52e-05	2	175	2	16775010
Pubmed	Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.	ZDHHC11B ZDHHC11	2.52e-05	2	175	2	35384384
Pubmed	Diagnostic Potential of Differentially Expressed Homer1 and Homer2 in Ischemic Stroke.	HOMER2 HOMER1	2.52e-05	2	175	2	27832625
Pubmed	Long-term maintenance of Na+ channels at nodes of Ranvier depends on glial contact mediated by gliomedin and NrCAM.	GLDN NRCAM	2.52e-05	2	175	2	24719088
Pubmed	Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.	ADGRV1 USH2A	2.52e-05	2	175	2	15671307
Pubmed	Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.	ERAP1 ERAP2	2.52e-05	2	175	2	16585582
Pubmed	Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.	ADGRV1 USH2A	2.52e-05	2	175	2	34638692
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	2.52e-05	2	175	2	15774318
Pubmed	Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.	ERAP1 ERAP2	2.52e-05	2	175	2	19433412
Pubmed	The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.	ERAP1 ERAP2	2.52e-05	2	175	2	22106953
Pubmed	Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.	ERAP1 ERAP2	2.52e-05	2	175	2	15908954
Pubmed	Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference.	HOMER2 HOMER1	2.52e-05	2	175	2	23658151
Pubmed	Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence.	ERAP1 ERAP2	2.52e-05	2	175	2	33309189
Pubmed	Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.	ERAP1 ERAP2	2.52e-05	2	175	2	29108111
Pubmed	Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.	ADGRV1 USH2A	2.52e-05	2	175	2	28653555
Pubmed	The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset.	ERAP1 ERAP2	2.52e-05	2	175	2	29183862
Pubmed	An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes.	ERAP1 ERAP2	2.52e-05	2	175	2	29991817
Pubmed	Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.	ERAP1 ERAP2	2.52e-05	2	175	2	28063628
Pubmed	The ERAP gene is associated with HCV chronic infection in a Chinese Han population.	ERAP1 ERAP2	2.52e-05	2	175	2	29037997
Pubmed	Activated HIF1α of tumor cells promotes chemoresistance development via recruiting GDF15-producing tumor-associated macrophages in gastric cancer.	HIF1A GDF15	2.52e-05	2	175	2	32388677
Pubmed	HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.	HIF1A NFAT5	2.52e-05	2	175	2	30982460
Pubmed	HIF1α promotes tumor chemoresistance via recruiting GDF15-producing TAMs in colorectal cancer.	HIF1A GDF15	2.52e-05	2	175	2	33242463
Pubmed	Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene.	ERAP1 ERAP2	2.52e-05	2	175	2	11481040
Pubmed	The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.	ERAP1 ERAP2	2.52e-05	2	175	2	36569828
Pubmed	Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier.	GLDN NRCAM	2.52e-05	2	175	2	16039564
Pubmed	Expression and regulation of Homer in human skeletal muscle during neuromuscular junction adaptation to disuse and exercise.	HOMER2 HOMER1	2.52e-05	2	175	2	21885651
Pubmed	Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso.	HIF1A ZBTB33	2.52e-05	2	175	2	26514431
Pubmed	ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.	ERAP1 ERAP2	2.52e-05	2	175	2	27514473
Pubmed	A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.	ERAP1 ERAP2	2.52e-05	2	175	2	36834865
Pubmed	The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia.	ERAP1 ERAP2	2.52e-05	2	175	2	32210971
Pubmed	Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrest.	TTK BUB1B	2.52e-05	2	175	2	25897860
Pubmed	Serum cytokine receptors in ankylosing spondylitis: relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms.	ERAP1 ERAP2	2.52e-05	2	175	2	20595269
Pubmed	ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.	ERAP1 ERAP2	2.52e-05	2	175	2	17088086
Pubmed	Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes.	ERAP1 ERAP2	2.52e-05	2	175	2	23696916
Pubmed	Co-expression of KIAA1199 and hypoxia-inducible factor 1α is a biomarker for an unfavorable prognosis in hepatocellular carcinoma.	HIF1A CEMIP	2.52e-05	2	175	2	33327261
Pubmed	Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.	ERAP1 ERAP2	2.52e-05	2	175	2	33762660
Pubmed	Nuclear respiratory factor-1 (NRF-1) regulated hypoxia-inducible factor-1α (HIF-1α) under hypoxia in HEK293T.	HIF1A NRF1	2.52e-05	2	175	2	27491637
Pubmed	Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.	HOMER2 HOMER1	2.52e-05	2	175	2	16314758
Pubmed	Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro: Role of Hif-1α.	HIF1A GDF15	2.52e-05	2	175	2	28734801
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	A2M HAUS7 FLNB ZFYVE16 TOPBP1 TXLNA RECQL5 BUB1B NAV1 LRIF1 HOMER1 TP53BP2 EXOC4	2.58e-05	645	175	13	25281560
Pubmed	Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.	ADAD1 KRT9 ZDHHC11B NRCAM ZDHHC11 CACNA2D3 EXOC4	2.71e-05	171	175	7	28700664
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	A2M NRDE2 RBL1 LAMB3 CEMIP PIK3R4 TXLNA BUB1B CRYBG3 PPIP5K2 RIC1 EXOC4 WDR48	2.79e-05	650	175	13	38777146
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KIF13B DNAJC13 NRF1 RBL1 MMADHC TXLNA THADA SETD5 SERINC1 NAV1 DYNLRB1 COL14A1 PPIP5K2 ZW10 ATP2B2 CLUH TP53BP2 EXOC4 WDR48	4.09e-05	1321	175	19	27173435
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRCAM ZFYVE16 TSPOAP1 PHLDB1 SETD5 STARD9 NAV1 TRAK2 NFAT5 WDR48	4.45e-05	407	175	10	12693553
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	ZC3H14 NRF1 LAMB3 CHAMP1 KIF20B KMT2D BUB1B ZW10 JRKL WDR48	4.73e-05	410	175	10	26949251
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	TRIO ERAP1 TAF1C NR4A2 SYNPO LENG9 KIF20B TXLNA THADA CLUH LRIF1 SYMPK WDR48	5.06e-05	689	175	13	36543142
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNB TRIO RNF19A MYO9B TXLNA SETD5 NAV1 TP53BP2 AHNAK2	5.08e-05	332	175	9	37433992
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB HIF1A DNAJC13 NRF1 TRIO KIZ ZBTB8A SYNPO ADGRV1 PLBD2 DNAH14 SLC7A1 PHLDB1 THADA SETD5 NAV1 NFAT5 CYP4F11 RIC1 EXOC4	6.56e-05	1489	175	20	28611215
Pubmed	The Genetic Basis of Baculum Size and Shape Variation in Mice.	HIF1A RBL1 SEC23A	6.68e-05	16	175	3	26935419
Pubmed	Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases.	ERAP1 ERAP2	7.53e-05	3	175	2	25142031
Pubmed	ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han.	ERAP1 ERAP2	7.53e-05	3	175	2	29480940
Pubmed	ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.	ERAP1 ERAP2	7.53e-05	3	175	2	37686141
Pubmed	PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.	ADGRV1 USH2A	7.53e-05	3	175	2	20440071
Pubmed	PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.	HOMER2 HOMER1	7.53e-05	3	175	2	14528310
Pubmed	ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis†.	ZDHHC11B ZDHHC11	7.53e-05	3	175	2	34897408
Pubmed	The oxytocinase subfamily of M1 aminopeptidases.	ERAP1 ERAP2	7.53e-05	3	175	2	16054015
Pubmed	Hypoxia-inducible factor 1alpha regulates lung adenocarcinoma cell invasion.	HIF1A MMP1	7.53e-05	3	175	2	17335808
Pubmed	Impaired phosphorylation and mis-localization of Bub1 and BubR1 are responsible for the defective mitotic checkpoint function in Brca2-mutant thymic lymphomas.	BRCA2 BUB1B	7.53e-05	3	175	2	14646599
Pubmed	HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers.	HIF1A BRCA2	7.53e-05	3	175	2	23409121
Pubmed	Differential expression of Homer family proteins in the developing mouse brain.	HOMER2 HOMER1	7.53e-05	3	175	2	15116392
Pubmed	ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.	ERAP1 ERAP2	7.53e-05	3	175	2	34727153
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	7.53e-05	3	175	2	38287013
Pubmed	Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.	HOMER2 HOMER1	7.53e-05	3	175	2	24530450
Pubmed	A conserved interaction that is essential for the biogenesis of histone locus bodies.	CASP8AP2 NPAT	7.53e-05	3	175	2	25339177
Pubmed	Non-USH2A mutations in USH2 patients.	ADGRV1 USH2A	7.53e-05	3	175	2	22147658
Pubmed	A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.	HIF1A HIVEP1	7.53e-05	3	175	2	2106471
Interaction	PHF21A interactions	CASP8AP2 FLNB DNAJC13 HIVEP1 ZBTB33 ZFYVE16 ICE1 INPP5F KIF20B KMT2D BRCA2 BUB1B NAV1 CRYBG3 TP53BP2 EXOC4 NPAT	5.98e-09	343	171	17	int:PHF21A
Cytoband	3q22.1	DNAJC13 TOPBP1 SRPRB PIK3R4	2.04e-05	42	175	4	3q22.1
GeneFamily	Homer scaffolding proteins	HOMER2 HOMER1	9.98e-05	3	105	2	871
GeneFamily	Fibronectin type III domain containing\|USH2 complex	ADGRV1 USH2A	1.99e-04	4	105	2	1244
GeneFamily	Nuclear factors of activated T-cells	NFATC4 NFAT5	3.30e-04	5	105	2	665
GeneFamily	Fibronectin type III domain containing	NRCAM ABI3BP TSPOAP1 COL14A1 MYOM2 USH2A	3.42e-04	160	105	6	555
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC11B ZDHHC5 ZDHHC11	3.53e-04	24	105	3	76
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE16 ZFYVE9 ZFYVE26	7.60e-04	31	105	3	81
GeneFamily	Laminin subunits	LAMA1 LAMB3	2.12e-03	12	105	2	626
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF13B KIF20B STARD9	2.41e-03	46	105	3	622
GeneFamily	Helix-turn-helix CENPB type domain containing	TIGD2 JRKL	2.50e-03	13	105	2	533
GeneFamily	Dyneins, axonemal	DNAH2 DNAH14	4.29e-03	17	105	2	536
GeneFamily	Aminopeptidases\|CD molecules	ERAP1 ERAP2	4.29e-03	17	105	2	104
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ZC3H14 FLNB HIF1A DNAJC13 HIVEP1 TRIO ZFYVE16 MYO9B TOPBP1 INPP5F TTK KIF20B CEMIP PIK3R4 SLC7A1 ZFYVE9 BRCA2 BUB1B N4BP1 CRYBG3 PPIP5K2 HOMER1 TP53BP2 NPAT	3.11e-09	856	175	24	M4500
Coexpression	GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP	HIVEP1 ZFYVE16 NR4A2 CFP INPP5F NSMF MYOM2 HAGH TRAK2 JRKL NPAT	1.12e-07	200	175	11	M8030
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	CASP8AP2 NRF1 ERAP1 RBL1 MTHFD2 TOPBP1 FAHD2A ANKRD36C CHAMP1 TTK KIF20B SLC7A1 BRCA2 ERAP2 BUB1B CCDC15 PRR11 ZW10 CDCA7L NPAT	5.07e-06	939	175	20	M45768
Coexpression	GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN	CASP8AP2 RBL1 TSBP1 CYP4F12 MYOM2 NFAT5 USH2A HOMER1 CACNA2D3	7.50e-06	197	175	9	M4540
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	FLNB DNAJC13 HIVEP1 TRIO TOPBP1 INPP5F KIF20B CEMIP SLC7A1 ZFYVE9 BUB1B HOMER1 TP53BP2	1.62e-05	466	175	13	M13522
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	ONECUT2 DNAJC13 TRIO MTHFD2 GDF15 TOPBP1 LAMB3 TTK KIF20B SLC7A1 BRCA2 BUB1B PRR11 TP53RK LRIF1 AHNAK2	2.88e-05	721	175	16	M10237
Coexpression	GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN	HIF1A HIVEP1 RNF19A ZDHHC5 SLC7A1 NSMF PIK3CG N4BP1	2.96e-05	180	175	8	M6717
Coexpression	GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP	LAMB3 ADGRV1 RFX7 SLC7A1 TSBP1 HSD11B1 CYP4F11 DMTN	5.23e-05	195	175	8	M8151
Coexpression	GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN	TSNAXIP1 MYH1 TOPBP1 TTK ZFYVE9 BRCA2 HOMER2	6.09e-05	147	175	7	M422
Coexpression	GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN	ZFYVE16 NR4A2 CFP NSMF EGR3 MYOM2 TRAK2 NPAT	6.25e-05	200	175	8	M8032
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M ONECUT2 MYH1 MGAM NRCAM LAMA1 APOB ADGRV1 XIRP2 MYOCD MYOM2 USH2A	1.00e-11	184	175	12	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M ONECUT2 MYH1 MGAM NRCAM LAMA1 APOB ADGRV1 XIRP2 MYOCD MYOM2 USH2A	1.00e-11	184	175	12	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M ONECUT2 MYH1 MGAM NRCAM LAMA1 APOB ADGRV1 XIRP2 MYOCD MYOM2 USH2A	1.00e-11	184	175	12	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB MTHFD2 GDF15 VSIG4 BUB1B ZFYVE26 CYB5R4 HOMER1	5.19e-07	177	175	8	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANKRD36C TTK BRCA2 STARD9 BUB1B NAV1 CCDC15 PRR11	8.87e-07	190	175	8	31de1727822e9818652946dfb962daee77ffad68
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TSNAXIP1 NRCAM GDF15 HEATR4 JPH1 TIGD2 HOMER2 VGLL1	1.30e-06	200	175	8	924eacea513dde8e3bd805a335bc4285647b800d
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GLDN NRCAM RECQL5 ZFYVE26 LRIF1 JRKL ZMYM6	6.09e-06	175	175	7	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	FAHD2A TTK KIF20B BRCA2 PRR11 KCNAB3 CDCA7L	8.16e-06	183	175	7	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	(01)_Dendritic_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	FLNB GLDN VSIG4 CYP46A1 NAV1 HOMER2 CACNA2D3	1.08e-05	191	175	7	1f4c8078e1a6cd14937c714330af608caced2acf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NRCAM LAMA1 LAMB3 ADGRV1 TTK BUB1B PRR11	1.12e-05	192	175	7	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RNF19A ZDHHC5 RHAG CYP4F12 HAGH TRAK2 DMTN	1.15e-05	193	175	7	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLDN ABI3BP TTK KIF20B BRCA2 BUB1B PRR11	1.27e-05	196	175	7	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MTHFD2 VSIG4 TTK KIF20B BRCA2 BUB1B PRR11	1.32e-05	197	175	7	2a89a724e8c15a5bb167fdad7eed31444d8c3d68
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Caecum / Region, Cell class and subclass	A2M VSIG4 TTK BUB1B MMP1 PRR11 CACNA2D3	1.45e-05	200	175	7	608be9bfe74f8d3202aa92b2905452a06f340f76
ToppCell	Caecum-(5)_Dendritic_cell-(52)_cycling_DCs\|Caecum / shred on region, Cell_type, and subtype	A2M VSIG4 TTK BUB1B MMP1 PRR11 CACNA2D3	1.45e-05	200	175	7	3b04d08e9122c23f42f66bc74c06cf24e1693987
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RBL1 TTK KIF20B BRCA2 BUB1B CCDC15 PRR11	1.45e-05	200	175	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	TRIO TAF1C ZNF518A KMT2D PPIP5K2 NFAT5	1.58e-05	135	175	6	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TSNAXIP1 GLDN LAMB3 PMEL NFS1 AHNAK2	2.86e-05	150	175	6	ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO9B NR4A2 RFX7 ITGAE SV2C ARMH4	3.56e-05	156	175	6	af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CHODL EGR3 CCDC15 MYOM2 TRAK2 DMTN	3.69e-05	157	175	6	542944030cd9b3f3559e64f9f6598694d74003c0
ToppCell	VE-mono3\|VE / Condition, Cell_class and T cell subcluster	A2M NRCAM VSIG4 NR4A2 RHAG HOMER1	4.25e-05	161	175	6	7df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCell	VE-mono3-\|VE / Condition, Cell_class and T cell subcluster	A2M NRCAM VSIG4 NR4A2 RHAG HOMER1	4.25e-05	161	175	6	4e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M ZNF213 SETD5 SERINC1 PROX2 KCNAB3	5.04e-05	166	175	6	9e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|Myeloid / Condition, Lineage and Cell class	HIVEP1 ZFYVE16 NR4A2 EGR3 NFAT5 TP53BP2	5.39e-05	168	175	6	ea465152ea31391b63c02425beafa9a4f51f6703
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ONECUT2 MGAM VSIG4 CYP46A1 KCNRG NPC1L1	5.39e-05	168	175	6	4e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ONECUT2 MGAM VSIG4 CYP46A1 KCNRG NPC1L1	5.39e-05	168	175	6	ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLDN DNAH2 TAMM41 BRCA2 EXOC4	5.41e-05	103	175	5	eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	RBL1 VSIG4 KIF20B BRCA2 BUB1B PRR11	5.57e-05	169	175	6	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CHODL NRCAM UBD SYNPO DNAI3 TAT	5.75e-05	170	175	6	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZBTB33 TAF1C KIF20B FSIP2 KCNAB3 HOMER1	5.94e-05	171	175	6	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO LAMA1 SORCS3 HOMER2 CACNA2D3 AHNAK2	6.14e-05	172	175	6	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO LAMA1 SORCS3 HOMER2 CACNA2D3 AHNAK2	6.14e-05	172	175	6	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 CACHD1 LRP4 PDIA2 HOMER2 RIC1	6.34e-05	173	175	6	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 CACHD1 LRP4 PDIA2 HOMER2 RIC1	6.34e-05	173	175	6	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|COVID-19 / Condition, Lineage and Cell class	ZFYVE16 GDF15 NR4A2 EGR3 NFAT5 TP53BP2	6.34e-05	173	175	6	502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLDN TRIO MYO9B VSIG4 ZFYVE26 ZMYM6	6.54e-05	174	175	6	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTK SYT7 BUB1B COL14A1 CRYBG3 SYMPK	6.54e-05	174	175	6	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM STXBP4 LAMA1 ADGRV1 DNAH14 CACNA2D3	6.75e-05	175	175	6	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	FAM120B STARD9 HAGH TP53RK ZW10 GPAT2	6.75e-05	175	175	6	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPOAP1 TOPBP1 ITGAE TTK BUB1B PRR11	6.97e-05	176	175	6	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	HIF1A RNF19A INPP5F THADA BUB1B HSD11B1	6.97e-05	176	175	6	56c055488e34605d32562571a2fee621b47c9441
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABI3BP CACHD1 LENG9 DNAH14 MYOM2 AHNAK2	7.42e-05	178	175	6	c655b72ec22d45d2da69c2d8886a01831ce79558
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM STXBP4 LAMA1 ADGRV1 HOMER1 CACNA2D3	7.42e-05	178	175	6	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 RBL1 TTK KIF20B BUB1B PRR11	7.65e-05	179	175	6	dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF13B FLNB MTHFD2 ZNF213 COL14A1 AHNAK2	7.65e-05	179	175	6	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NRCAM KIZ DNAI3 XIRP2 CRYBG3 CACNA2D3	7.65e-05	179	175	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	TOPBP1 EXOSC1 ZNF213 NFS1 SLC7A1 BRCA2	7.89e-05	180	175	6	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NRCAM RNF19A KIZ CEMIP CRYBG3 CACNA2D3	8.38e-05	182	175	6	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	facs-Heart-RA-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 XIRP2 MYOCD MYOM2 HOMER2 HOMER1	8.90e-05	184	175	6	72b42dfca7e9c0257f11d8242531e843271871a7
ToppCell	wk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RHAG BRCA2 BUB1B HAGH TRAK2 DMTN	8.90e-05	184	175	6	238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell	facs-Heart-RA-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 XIRP2 MYOCD MYOM2 HOMER2 HOMER1	8.90e-05	184	175	6	c6f4537ae8b6e8fde1be17df14629b7b49b4997c
ToppCell	(7)_DC_activated\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	GLDN NRCAM UBD SYNPO NAV1 TAT	8.90e-05	184	175	6	b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 ADGRV1 NFATC4 LRP4 CYP4F12 CYP4F11	8.90e-05	184	175	6	22c18964818fc9c8f18051f836d718937b0d8d12
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP LAMA1 CACHD1 ZFYVE9 COL14A1 GPAT2	9.17e-05	185	175	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RNF19A RHAG CYP4F12 HAGH TRAK2 DMTN	9.17e-05	185	175	6	e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	RBL1 TTK KIF20B BRCA2 BUB1B PRR11	9.17e-05	185	175	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP LAMA1 CACHD1 ZFYVE9 COL14A1 GPAT2	9.17e-05	185	175	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP LAMA1 CACHD1 ZFYVE9 COL14A1 GPAT2	9.17e-05	185	175	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM STXBP4 LAMA1 ADGRV1 DNAH14 CACNA2D3	9.17e-05	185	175	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 CYP4F11	9.45e-05	186	175	6	73cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LAMB3 CEMIP NAV1 HSD11B1 CEACAM20 HOMER2	9.45e-05	186	175	6	0dce13e15c3bf32610bf2dad31253b52a39cff87
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ONECUT2 ZDHHC11B ERICH5 PDIA2 MMP1 HOMER2	9.45e-05	186	175	6	6d8dd6d0403d149cb6edb346581fe6c248036785
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM STXBP4 LAMA1 ADGRV1 SYT7 CACNA2D3	9.73e-05	187	175	6	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM STXBP4 LAMA1 ADGRV1 SYT7 CACNA2D3	9.73e-05	187	175	6	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	APOB ITIH2 RHAG HAGH TAT DMTN	9.73e-05	187	175	6	edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VSIG4 TTK KIF20B BRCA2 BUB1B PRR11	9.73e-05	187	175	6	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NRCAM ABI3BP LRP4 COL14A1 HSD11B1 PEAK1	1.00e-04	188	175	6	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	FLNB LAMB3 CACHD1 ADGRV1 SERPINB11 HOMER2	1.03e-04	189	175	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTK KIF20B BRCA2 BUB1B CCDC15 PRR11	1.03e-04	189	175	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 CYP4F11	1.06e-04	190	175	6	78cc6c28b31de041c24175a98f47da256ecc15a2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 TP53BP2	1.06e-04	190	175	6	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	RBL1 TOPBP1 TTK BRCA2 PRR11 GPAT2	1.06e-04	190	175	6	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 CYP4F11	1.06e-04	190	175	6	e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 TP53BP2	1.06e-04	190	175	6	b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RBL1 TTK KIF20B BRCA2 BUB1B PRR11	1.06e-04	190	175	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 CACHD1 ADGRV1 NFATC4 LRP4 TP53BP2	1.06e-04	190	175	6	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO LAMA1 DNAH14 NFAT5 HOMER1 CACNA2D3	1.09e-04	191	175	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	TTK KIF20B BRCA2 BUB1B CCDC15 PRR11	1.09e-04	191	175	6	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HIF1A LAMA1 ADGRV1 SORCS3 COL14A1 CACNA2D3	1.09e-04	191	175	6	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RBL1 TTK KIF20B RHAG BRCA2 BUB1B	1.09e-04	191	175	6	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	A2M KIF13B RNF19A ANKRD36C NFAT5 EXOC4	1.09e-04	191	175	6	9454f642c3621370fa23640b631301346b300950
ToppCell	Mild-Myeloid-mDC\|Mild / Condition, Lineage, Cell class and cell subclass	UBD CFP SYNPO NAV1 HOMER2 CACNA2D3	1.12e-04	192	175	6	da3952bd5c96242c15eb76678d0608ae2926a16e
ToppCell	Mild-Myeloid-mDC-\|Mild / Condition, Lineage, Cell class and cell subclass	UBD CFP SYNPO NAV1 HOMER2 CACNA2D3	1.12e-04	192	175	6	8520b3fdf4508ac66f7918da613abc928ab5832a
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMB3 CACHD1 ADGRV1 SERPINB11 MMP1 HOMER2	1.12e-04	192	175	6	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRIO MYO9B SV2C NFAT5 EXOC4 ARMH4	1.16e-04	193	175	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RBL1 TTK KIF20B BRCA2 BUB1B PRR11	1.16e-04	193	175	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TTK KIF20B BRCA2 BUB1B CCDC15 CDCA7L	1.16e-04	193	175	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 FSIP2 SV2C BAIAP2L2	1.17e-04	64	175	4	bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 FSIP2 SV2C BAIAP2L2	1.17e-04	64	175	4	a3e852600c53b11175eb579e92962fa711f5678b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 FSIP2 SV2C BAIAP2L2	1.17e-04	64	175	4	f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VSIG4 TTK KIF20B BRCA2 BUB1B PRR11	1.19e-04	194	175	6	e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCell	368C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HIF1A ZFYVE16 NR4A2 CFP PHLDB1 NFAT5	1.19e-04	194	175	6	f9b9cbd1a418a7cbd151c2425fda6b864db9aa82
ToppCell	Bronchial_Brush-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	MTHFD2 NR4A2 CFP PHLDB1 NFAT5 CACNA2D3	1.19e-04	194	175	6	dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	VSIG4 TTK KIF20B BRCA2 BUB1B PRR11	1.19e-04	194	175	6	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	BAL-Mild-Myeloid-cDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M UBD CFP NAV1 HOMER2 CACNA2D3	1.22e-04	195	175	6	6ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIF1A GLDN ZFYVE16 MYO9B VSIG4 CYB5R4	1.22e-04	195	175	6	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBL1 TOPBP1 TTK KIF20B BUB1B PRR11	1.22e-04	195	175	6	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	BAL-Mild-Myeloid-cDC-cDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	A2M UBD CFP NAV1 HOMER2 CACNA2D3	1.22e-04	195	175	6	66e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCell	BAL-Mild-Myeloid-cDC-cDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M UBD CFP NAV1 HOMER2 CACNA2D3	1.22e-04	195	175	6	7209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCell	(010)_cDC\|World / immune cells in Peripheral Blood (logTPM normalization)	GLDN VSIG4 CFP NAV1 HOMER2 CACNA2D3	1.22e-04	195	175	6	4aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
Disease	obstructive lung disease (is_implicated_in)	A2M MMP1	3.22e-05	2	168	2	DOID:2320 (is_implicated_in)
Disease	Malignant neoplasm of breast	MYH1 FLNB HIF1A TBC1D9B CATSPERE NRCAM UBD STXBP4 CFP PIK3R4 KMT2D BRCA2 ZFYVE26 MMP1 HSD11B1 CYB5R4 TP53BP2	1.44e-04	1074	168	17	C0006142
Disease	cerebral infarction (is_marker_for)	A2M HIF1A APOB	1.64e-04	19	168	3	DOID:3526 (is_marker_for)
Disease	non-high density lipoprotein cholesterol measurement	KIF13B DNAJC13 HIVEP1 APOB THADA TAMM41 BRCA2 PROX2 NPC1L1 CYP4F12 TRAK2 BAIAP2L2 DMTN	2.37e-04	713	168	13	EFO_0005689
Disease	cardiovascular disease	ERAP1 MYO9B APOB SLC7A1 THADA ERAP2 NPC1L1 NAV1 SORCS3 NFAT5	3.07e-04	457	168	10	EFO_0000319
Disease	aortic valve stenosis (is_implicated_in)	APOB MMP1	3.19e-04	5	168	2	DOID:1712 (is_implicated_in)
Disease	endoplasmic reticulum aminopeptidase 1 measurement	ERAP1 ERAP2	6.64e-04	7	168	2	EFO_0008119
Disease	osteonecrosis (biomarker_via_orthology)	A2M HIF1A	6.64e-04	7	168	2	DOID:10159 (biomarker_via_orthology)
Disease	non-melanoma skin carcinoma	UBD RNF19A DNAH2 NFS1 BRCA2 TRAK2 ARMH4	8.43e-04	265	168	7	EFO_0009260
Disease	severe pre-eclampsia (is_marker_for)	ERAP1 ERAP2	8.82e-04	8	168	2	DOID:13129 (is_marker_for)
Disease	sporadic amyotrophic lateral sclerosis	CHODL TMEM132B ZFYVE26 MYOM2 ATP2B2	1.27e-03	140	168	5	EFO_0001357
Disease	cortical thickness	A2M FLNB LAMA1 ADGRV1 KIF20B PHLDB1 THADA SETD5 PROX2 NAV1 LRP4 CLUH HOMER2 CACNA2D3 EXOC4	1.81e-03	1113	168	15	EFO_0004840
Disease	PARKINSON DISEASE, LATE-ONSET	DNAJC13 NR4A2	2.05e-03	12	168	2	C3160718
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KMT2D BRCA2 COL14A1	2.16e-03	45	168	3	DOID:3748 (is_implicated_in)
Disease	liver cirrhosis (implicated_via_orthology)	PIK3CG MMP1	2.41e-03	13	168	2	DOID:5082 (implicated_via_orthology)
Disease	X-24588 measurement	HEATR4 ANKRD40	2.41e-03	13	168	2	EFO_0800898
Disease	Celiac Disease	UBD MYO9B APOB	2.45e-03	47	168	3	C0007570
Disease	frontal fibrosing alopecia	EFCAB5 ERAP1 ERAP2	2.60e-03	48	168	3	EFO_0009855
Disease	skin melanoma (is_implicated_in)	BRCA2 MMP1	2.80e-03	14	168	2	DOID:8923 (is_implicated_in)
Disease	response to olanzapine	HIVEP1 ADGRV1	3.22e-03	15	168	2	GO_0097333
Disease	Metastatic melanoma	TRIO GUCY2D PEAK1	3.63e-03	54	168	3	C0278883
Disease	cholesteatoma of middle ear (is_marker_for)	HIF1A MMP1	3.67e-03	16	168	2	DOID:10964 (is_marker_for)
Disease	ovarian cancer (is_implicated_in)	APOB BRCA2 MMP1	4.03e-03	56	168	3	DOID:2394 (is_implicated_in)
Disease	thrombomodulin measurement	ONECUT2 LAMA1	4.14e-03	17	168	2	EFO_0007774
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO RFX7	4.14e-03	17	168	2	DOID:0060307 (is_implicated_in)
Disease	blood osmolality measurement	CEMIP CYB5R4 NFAT5	4.45e-03	58	168	3	EFO_0007967
Disease	cortical thickness change measurement	MMADHC EGR3	4.64e-03	18	168	2	EFO_0021501
Disease	apolipoprotein B measurement	KIF13B DNAJC13 APOB THADA BRCA2 NPC1L1 SV2C CEACAM20 DMTN SYMPK	4.85e-03	663	168	10	EFO_0004615
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	APOB BRCA2 NPC1L1 CEACAM20	4.99e-03	120	168	4	EFO_0004611, EFO_0004639

Protein segments in the cluster

Peptide	Gene	Start	Entry
QIASESQKIPGMTLS	BUB1B	481	O60566
IVLSTQMATLGQKPV	CATSPERE	146	Q5SY80
GKTEVMPLALEVVNT	CRYBG3	1751	Q68DQ2
SIAVSPGTAIEQKDM	CEACAM20	71	Q6UY09
TSKQTPQLVVSEDPM	ARMH4	61	Q86TY3
SKSTQNLIGAMEEVP	ADGRV1	6196	Q8WXG9
IGDEVITLNMIKSAP	CACHD1	1081	Q5VU97
QLDLKETVTTGNVMG	ADAD1	111	Q96M93
ESMITSIGNPVQVLK	GLDN	301	Q6ZMI3
EILTTKGEMPVQLTS	ANKRD40	71	Q6AI12
TVAALPMLKQSNGSI	HSD11B1	151	P28845
IVVNTEGIPIKSTMD	DYNLRB1	21	Q9NP97
GMQVIPQIKDISTQT	DNAI3	231	Q8IWG1
EIQQTESLFPSTGMK	CASP8AP2	686	Q9UKL3
ATIPDNSIVLMASKG	CEMIP	1281	Q8WUJ3
LVIQASEGPMKIQTL	TP53BP2	376	Q13625
DPSSINTKTMELLIN	ATP2B2	526	Q01814
SNEEVMFLTVQVKGP	A2M	96	P01023
QKIMEVASPTAGSVL	TSPOAP1	1026	O95153
VSTENGITLKMPQQA	RIC1	651	Q4ADV7
MAIGIEKNSLSSNVP	NPAT	481	Q14207
VPNMATETKDEQISG	ANKRD36C	971	Q5JPF3
PEVANGKLMILTVTQ	MMADHC	166	Q9H3L0
QVTSPQATKETGMEI	LETM2	101	Q2VYF4
IQMSSKGNLPSILDV	TAT	6	P17735
IPLVQSSVMSDALKG	LRIF1	56	Q5T3J3
SVMTVNNEIGVKQPI	NFS1	201	Q9Y697
GDSEVIMESKQNPVS	FAM177A1	196	Q8N128
PVISMLAQGSQVLES	ITIH2	676	P19823
SFDGSLIQKMQIPTL	ZBTB33	366	Q86T24
VMAVNSIGKSLPSEA	NRCAM	721	Q92823
MVSGPNKIILTVDDI	GUCY2D	496	Q02846
GGILTANEKSTMQEL	KRT9	146	P35527
NLTVDEGTMKVEVLP	HAGH	41	Q16775
EGTMKVEVLPALTDN	HAGH	46	Q16775
SEQNGMEQKTIILIP	HIF1A	761	Q16665
DGAKVIINSTITPNM	HOMER2	51	Q9NSB8
NEIKILGMEEPSNVT	MGAM	1796	O43451
KEVVDMLPGIQQTSA	KIAA1109	3311	Q2LD37
KEANSGPNSIMIVLV	JPH1	631	Q9HDC5
PTSQILGEILVQMSD	BAIAP2L2	66	Q6UXY1
ISQMEPSSISILKEN	FSIP2	3101	Q5CZC0
NLTTVINSPKMQGVE	ITGAE	321	P38570
ISNMPLVKSVTVAEG	ERAP1	216	Q9NZ08
TVMSLQESGLKVNQP	FLNB	2291	O75369
LMVTEPGLQAEVTKA	LENG9	326	Q96B70
PVAKIEGTQESQMVG	PEAK1	741	Q9H792
SSPIDISGQVILMDQ	KIF20B	1786	Q96Q89
LMNIDGVAISSKTEP	NRDE2	231	Q9H7Z3
DGIPVSVDKMTQAQL	NRF1	191	Q16656
PSKEMQITISQQLGL	ONECUT2	451	O95948
SPLELSAQGKQMIET	NSMF	491	Q6X4W1
LMKSSENGALPVVSV	EXOSC1	41	Q9Y3B2
TLPKTMTQFLEQGEA	FAHD2A	61	Q96GK7
PMVLIQKTDTGVSLQ	GDF15	281	Q99988
SLIQPSDQGVIATMK	JRKL	321	Q9Y4A0
MSSQELVTLNVGGKI	KCNRG	1	Q8N5I3
TSGKMQGTLEDQIIS	MYH1	211	P12882
DLNGKTNPEVMVVES	CDCA7L	91	Q96GN5
ESMVVTLAKVDGPAQ	PDIA2	91	Q13087
PTVSMVEGQGEKNVT	CFP	416	P27918
QIGEKMPVTASVLSE	KIZ	231	Q2M2Z5
TVIEVGLDPSNNMTL	NFAT5	366	O94916
DGSKAIINSTITPNM	HOMER1	51	Q86YM7
LNSQSPLGKMSDVTL	MYOCD	811	Q8IZQ8
TTKQPITEAEMLKGV	MAGEA13P	121	A6NCF6
KNPELSGSLMTLSNV	NPC1L1	41	Q9UHC9
QAISDGVTNPKMLVV	PROX2	501	Q3B8N5
TLVPGVENMLTQVEK	EFCAB5	181	A4FU69
PVSEQIMQTLSELAK	EXOC4	751	Q96A65
GQTMEQLTPELKSSI	APOB	496	P04114
VGGPQENSVKILDTM	ICE1	1741	Q9Y2F5
VIMNAPSIGQVDSSK	BRCA2	1166	P51587
EILEAKADGQTPVSM	CYP46A1	166	Q9Y6A2
TLPKTMTQFLEQGEA	FAHD2B	61	Q6P2I3
KLTDDQGPVLMTTVA	CACNA2D3	466	Q8IZS8
SIPALSMETQKLGSV	CHAMP1	126	Q96JM3
LQEIEGPSVSIMEKT	COL14A1	991	Q05707
TENVMDIGLTNEKPN	EGR3	51	Q06889
LVTPTEEGMKTLTQL	CYP4F11	66	Q9HBI6
LITPTEEGLKNSTQM	CYP4F12	66	Q9HCS2
QAETVEIMPGNKSTE	HEATR4	301	Q86WZ0
PQKIMESTGVQNLLS	GPAT2	111	Q6NUI2
SLKGVPTEVKIQEMT	HAUS7	86	Q99871
VTEILKMLNSNTESP	DNAJC13	1626	O75165
LVSIMDLPNKTGSII	DNAH14	626	Q0VDD8
ISKPAETPTQIQEMF	ERAP2	436	Q6P179
LPTDSATVLQKMNEI	LAMB3	921	Q13751
TAAEMKPLGTTENVL	ERICH5	181	Q6P6B1
SPSSIVAKMDNQVLG	DMTN	26	Q08495
VKPIGNVVTEATLDM	DNAH2	2581	Q9P225
GMISTPDAVLQAVIK	RNF41	216	Q9H4P4
QITKQAMGSDLPIIE	INPP5F	731	Q9Y2H2
GPEVKQQVTMVSDTE	FAM120B	561	Q96EK7
LSQLTPQTVMEIDGL	KCNAB3	381	O43448
MPLSGQQSSIKVEDI	NR4A2	81	P43354
MLGSSVKSVQPEVEL	NAV1	1	Q8NEY1
DITSEGQVMLTPQKN	KIF13B	496	Q9NQT8
GEVSIPLNKVDLTQM	SYT7	236	O43581
MDVEIQDTPGKISIS	SPATA48	1	A4D263
NSQGSLITDPITIAM	USH2A	2416	O75445
QVLIDSMGLKNTPSF	SRPRB	161	Q9Y5M8
TIPSQILEVMGDQSL	THADA	476	Q6YHU6
IPSMNQAKDSIVSVG	SV2C	96	Q496J9
MDTEVLNTAILTGKP	TMEM132B	426	Q14DG7
VSGTKVLEMTLLPEN	NFATC4	501	Q14934
PLTFTKVSEGQADIM	MMP1	146	P03956
AAAVVGINSETIMKP	MTHFD2	91	P13995
AENVSILPGQTLLTM	RBL1	691	P28749
EMIGSVSQSENAPKI	SORCS3	1166	Q9UPU3
QAVPASKTGILEESM	SYNPO	601	Q8N3V7
QPTLLQAMQVEKGAT	TAF1C	326	Q15572
ENNPVEMKLGTLVES	LAMA1	2601	P25391
LLNSGVSMPVIQTKE	NEPRO	506	Q6NW34
TSLQEGQMIISLPES	SETD4	66	Q9NVD3
KQALEEGMTQTSSVP	SETD5	786	Q9C0A6
TVVKLQPGDMAAITT	SKIV2L	916	Q15477
INVSLEKDMPGESAV	STARD9	1931	Q9P2P6
GKSTIDPSSVMVLVN	SERPINB11	166	Q96P15
VLNGMLPKSQVTDTL	CYB5R4	146	Q7L1T6
SLAVVSTQLIMPGQE	PMEL	576	P40967
DAAKMNIPTVGIVDT	MRPS2	211	Q9Y399
PGDQLVSVNKESMIG	STXBP4	66	Q6ZWJ1
QEMLGLSKVPLTQAT	SEC23A	201	Q15436
VGASVMSILPKIQES	SERINC1	241	Q9NRX5
PQLSEKMQDLGVISS	TBC1D9B	651	Q66K14
SMQGDLKTTDLSIQP	AHNAK2	1036	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	1201	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	1366	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	2026	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	2191	Q8IVF2
SMQGDLKTTDLSVQP	AHNAK2	2356	Q8IVF2
SMQGDLKTTDISIQP	AHNAK2	2686	Q8IVF2
SMQGDLKNTDISIEP	AHNAK2	3181	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	3676	Q8IVF2
SMQGDLKTTDLSIQP	AHNAK2	3841	Q8IVF2
TGIQSVKPDTQAVEM	CCDC15	351	Q0P6D6
ESMLQNLTKPGTGIS	CHODL	81	Q9H9P2
IDGNVMAINPSEETK	CLUH	401	O75153
SAVPTVLAMKNGDVV	TXN2	131	Q99757
TNPDKENSMSISILL	PIK3CG	506	P48736
TPLQESATMAVVKGN	RECQL5	31	O94762
SDPENIVKQTLMENG	PIK3R4	546	Q99570
EMPLQKTNEEVSLSG	XIRP2	2411	A4UGR9
IMTAKPFESGLQQTE	TRAK2	436	O60296
SLIQPMSQGVLATVK	TIGD2	321	Q4W5G0
KAMIETKTGIIPETQ	UBD	116	O15205
GKLSLTGQNVIEVMS	ZBTB8A	86	Q96BR9
MNQLGTIIVSGSTEK	WDR48	176	Q8TAF3
GNSMEVQVDIESKPS	RNF19A	611	Q9NV58
MEPSKISGLIVNIST	SLC7A1	486	P30825
TVLEQLNITKPTDMG	RHAG	31	Q02094
MSSSDGKVLPLNVQV	RFX7	286	Q2KHR2
KVPGDVSLQLSTLEM	VSIG4	91	Q9Y279
TSSVKAVLIPNMLSE	ZNF518A	1056	Q6AHZ1
QTMVQKGPLDLIETG	PHLDB1	16	Q86UU1
EIDKSPEGQFTQLMT	TAMM41	236	Q96BW9
PNSIMTILEASGKQE	SYMPK	1091	Q92797
STLGLQQETTEPMKT	ZDHHC11	391	Q9H8X9
PEVSDGQITVKIMDN	ZDHHC5	271	Q9C0B5
VMSLAKIPATLSTGN	ZMYM6	631	O95789
MQPDTTSVVKDSQVG	TTK	671	P33981
GQSEKSLLQEMVPVV	ZNF213	246	O14771
IQSTMETEKTPQGLS	TP53RK	126	Q96S44
LEQIPGMVVVADKTS	PLBD2	401	Q8NHP8
GELTPILVQMVKSAN	PPIP5K2	586	O43314
TLGLQQETTEPMKTD	ZDHHC11B	351	P0C7U3
QKLEIFTSPEMQPTT	ABI3BP	436	Q7Z7G0
GLMTIDPSLDKQTVN	TSNAXIP1	591	Q2TAA8
TQLKISEMSIPQGQG	TSBP1	306	Q5SRN2
QEIMSATSIVKPQGQ	TOPBP1	1076	Q92547
QELTPSSQSEGVMLK	VGLL1	56	Q99990
EEVVVAPNQESGMKT	ZC3H14	476	Q6PJT7
TQSLSLAVIPEGKIM	ZFYVE26	2141	Q68DK2
VTNVLITPGKSQMDL	PRR11	281	Q96HE9
TPLTNKENMETGTGL	PRR11	311	Q96HE9
QSLPSLSMETVNIVG	HIVEP1	2486	P15822
EKPSQISVMQQLEDG	ZFYVE9	921	O95405
TASVSSKGPMILLQA	ZP4	476	Q12836
TNMVSLEGLTKVVDP	TRIO	181	O75962
ISQVPSVEKLSMNTG	ZFYVE16	941	Q7Z3T8
KSSIVEDGLMVQITP	ZFYVE16	1336	Q7Z3T8
MQTLNTLSTPEEKLA	TXLNA	176	P40222
PSMQSAQGLITQVDK	ZW10	51	O43264
QKMVNGVTPSEELGE	KMT2D	4636	O14686
INITMKNTIAIGVDP	LRP4	1076	O75096
GTPVSELTKQMDTVL	N4BP1	241	O75113
QPQAMAVGKVSEETE	MYO9B	1221	Q13459
PDVVTIMEGKTLNLT	MYOM2	1351	P54296
QVQGQEVLSEKMEPS	MZF1	136	P28698