Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	zinc ion binding	TRIM46 ZMYM2 ZCCHC4 BAZ1B HERC2 ZFR2 ZMYM4 POLE ZMYM3 PML	3.45e-06	891	37	10	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	TRIM46 ZMYM2 ZCCHC4 BAZ1B HERC2 ZFR2 ZMYM4 POLE ZMYM3 PML	4.28e-05	1189	37	10	GO:0046914
GeneOntologyMolecularFunction	SUMO binding	HERC2 PML	5.60e-04	19	37	2	GO:0032183
HumanPheno	Attention deficit hyperactivity disorder	GABRG2 ZMYM2 BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	6.76e-06	413	15	8	HP:0007018
HumanPheno	Reduced impulse control	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3 PML	1.37e-05	1032	15	11	HP:5200045
HumanPheno	Abnormal morphology of female internal genitalia	ZMYM2 RSPO2 BAZ1B PLA2G2A FKBP6 HERC2 RREB1 POLE PML	2.51e-05	665	15	9	HP:0000008
HumanPheno	Abnormally increased volition	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	2.61e-05	869	15	10	HP:5200263
HumanPheno	Short attention span	GABRG2 ZMYM2 BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	3.60e-05	517	15	8	HP:0000736
HumanPheno	Reduced attention regulation	GABRG2 ZMYM2 BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	4.09e-05	526	15	8	HP:5200044
HumanPheno	Abnormality of the female genitalia	ZMYM2 RSPO2 BAZ1B PLA2G2A FKBP6 HERC2 RREB1 POLE PML	6.11e-05	741	15	9	HP:0010460
HumanPheno	Hyperactivity	GABRG2 ZMYM2 BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	6.30e-05	558	15	8	HP:0000752
HumanPheno	Cryptorchidism	ZMYM2 RSPO2 BAZ1B FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3	9.27e-05	780	15	9	HP:0000028
HumanPheno	Abnormal large intestine morphology	GABRG2 ZMYM2 BAZ1B PLA2G2A FKBP6 RREB1 CPLANE1 POLE	9.93e-05	594	15	8	HP:0002250
HumanPheno	Carious teeth	ZMYM2 BAZ1B FKBP6 HERC2 RREB1	9.98e-05	174	15	5	HP:0000670
HumanPheno	Sleep abnormality	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 ZMYM3	1.02e-04	596	15	8	HP:0002360
HumanPheno	Constitutional symptom	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 RREB1 FHL2 POLE ZMYM3 PML	1.15e-04	1276	15	11	HP:0025142
HumanPheno	Retinal arteriolar tortuosity	BAZ1B FKBP6 RREB1	1.17e-04	34	15	3	HP:0001136
HumanPheno	Ectopic kidney	ZMYM2 BAZ1B FKBP6 ZMYM3	1.22e-04	93	15	4	HP:0000086
HumanPheno	Disinhibition	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	1.22e-04	807	15	9	HP:0000734
HumanPheno	Inappropriate behavior	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	1.22e-04	807	15	9	HP:0000719
HumanPheno	Abnormal response to social norms	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	1.22e-04	807	15	9	HP:5200123
HumanPheno	Social disinhibition	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	1.22e-04	807	15	9	HP:5200029
HumanPheno	Recurrent maladaptive behavior	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3 PML	1.31e-04	1293	15	11	HP:5200241
HumanPheno	Pelvic kidney	ZMYM2 BAZ1B FKBP6	1.64e-04	38	15	3	HP:0000125
HumanPheno	Abnormal experience of reality	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE	1.82e-04	646	15	8	HP:5200423
HumanPheno	Abnormal aortic arch morphology	BAZ1B FKBP6 RREB1 ZMYM3	2.26e-04	109	15	4	HP:0012303
HumanPheno	Vesicoureteral reflux	ZMYM2 BAZ1B FKBP6 RREB1 ZMYM3	3.09e-04	221	15	5	HP:0000076
HumanPheno	Abnormal social development	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	3.13e-04	908	15	9	HP:0025732
HumanPheno	Abnormal spinal cord morphology	ZMYM2 BAZ1B MFN2 FKBP6 RREB1 CPLANE1	3.30e-04	357	15	6	HP:0002143
HumanPheno	Abnormal penis morphology	ZMYM2 RSPO2 BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	3.63e-04	712	15	8	HP:0000036
HumanPheno	Restricted or repetitive behaviors or interests	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2	3.90e-04	368	15	6	HP:0031432
HumanPheno	Dysgraphia	BAZ1B FKBP6 POLE	4.43e-04	53	15	3	HP:0010526
HumanPheno	Perseverative thought	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2	4.45e-04	377	15	6	HP:0030223
HumanPheno	Blue irides	BAZ1B FKBP6 HERC2	4.68e-04	54	15	3	HP:0000635
HumanPheno	Abnormal ureter physiology	ZMYM2 BAZ1B FKBP6 RREB1 ZMYM3	4.99e-04	245	15	5	HP:0025634
HumanPheno	Disordered formal thought process	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2	5.05e-04	386	15	6	HP:0025769
HumanPheno	Abnormal internal genitalia	ZMYM2 RSPO2 BAZ1B PLA2G2A FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3 PML	5.46e-04	1498	15	11	HP:0000812
HumanPheno	Urethral stenosis	ZMYM2 BAZ1B FKBP6	5.50e-04	57	15	3	HP:0008661
HumanPheno	Retinal vascular tortuosity	BAZ1B FKBP6 RREB1	5.50e-04	57	15	3	HP:0012841
HumanPheno	Abnormal thought pattern	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2	6.47e-04	404	15	6	HP:5200269
HumanPheno	Autism	GABRG2 BAZ1B FKBP6 HERC2 RREB1	7.04e-04	264	15	5	HP:0000717
HumanPheno	Abnormal motivation	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	7.27e-04	1263	15	10	HP:5200275
HumanPheno	Abnormal volitional state	GABRG2 ZMYM2 BAZ1B MFN2 FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	7.27e-04	1263	15	10	HP:0025780
HumanPheno	Posterior embryotoxon	BAZ1B FKBP6 RREB1	8.84e-04	67	15	3	HP:0000627
HumanPheno	Abnormal line of Schwalbe morphology	BAZ1B FKBP6 RREB1	8.84e-04	67	15	3	HP:0008048
HumanPheno	Urethral obstruction	ZMYM2 BAZ1B FKBP6	9.63e-04	69	15	3	HP:0000796
HumanPheno	Poor fine motor coordination	GABRG2 MFN2 HERC2	9.63e-04	69	15	3	HP:0007010
HumanPheno	Renal cyst	RSPO2 BAZ1B FKBP6 RREB1 ZMYM3	9.67e-04	283	15	5	HP:0000107
HumanPheno	Abnormal retinal artery morphology	BAZ1B FKBP6 RREB1	1.00e-03	70	15	3	HP:0000630
HumanPheno	Patellar dislocation	BAZ1B FKBP6 RREB1	1.05e-03	71	15	3	HP:0002999
HumanPheno	Depression	GABRG2 BAZ1B FKBP6 TRANK1 RREB1 POLE	1.12e-03	448	15	6	HP:0000716
HumanPheno	Spina bifida	BAZ1B FKBP6 RREB1 CPLANE1	1.25e-03	171	15	4	HP:0002414
HumanPheno	Nystagmus-induced head nodding	BAZ1B FKBP6	1.34e-03	19	15	2	HP:0001361
HumanPheno	Abnormal joint physiology	GABRG2 ZMYM2 RSPO2 BAZ1B MFN2 FKBP6 RREB1 CPLANE1 POLE ZMYM3	1.35e-03	1358	15	10	HP:0034430
HumanPheno	Abnormality of joint mobility	GABRG2 ZMYM2 RSPO2 BAZ1B MFN2 FKBP6 RREB1 CPLANE1 POLE ZMYM3	1.35e-03	1358	15	10	HP:0011729
HumanPheno	Abnormality of the urethra	ZMYM2 BAZ1B FKBP6 RREB1 POLE ZMYM3	1.37e-03	465	15	6	HP:0000795
HumanPheno	Multiple renal cysts	BAZ1B FKBP6 RREB1	1.38e-03	78	15	3	HP:0005562
HumanPheno	Abnormality of extrapyramidal motor function	GABRG2 ZMYM2 BAZ1B FKBP6 RREB1	1.38e-03	306	15	5	HP:0002071
HumanPheno	Constipation	BAZ1B FKBP6 HERC2 RREB1 POLE ZMYM3	1.48e-03	472	15	6	HP:0002019
HumanPheno	Abnormality of the larynx	GABRG2 RSPO2 BAZ1B MFN2 FKBP6 HERC2 RREB1	1.57e-03	666	15	7	HP:0001600
HumanPheno	Abnormal head blood vessel morphology	BAZ1B FKBP6 RREB1	1.59e-03	82	15	3	HP:3000036
HumanPheno	High hypermetropia	ZMYM2 BAZ1B FKBP6	1.59e-03	82	15	3	HP:0008499
HumanPheno	Hypoplastic toenails	ZMYM2 BAZ1B FKBP6	1.59e-03	82	15	3	HP:0001800
HumanPheno	Bowing of the long bones	RSPO2 BAZ1B FKBP6 HERC2 CPLANE1	1.59e-03	316	15	5	HP:0006487
HumanPheno	Scoliosis	ZMYM2 BAZ1B MFN2 FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3	1.61e-03	1122	15	9	HP:0002650
HumanPheno	Embryotoxon	BAZ1B FKBP6 RREB1	1.65e-03	83	15	3	HP:0100740
HumanPheno	Cholelithiasis	BAZ1B FKBP6 RREB1	1.65e-03	83	15	3	HP:0001081
HumanPheno	Maladaptive fear-related cognitions	GABRG2 BAZ1B FKBP6 TRANK1 RREB1 POLE	1.67e-03	483	15	6	HP:5200230
HumanPheno	Anxiety	GABRG2 BAZ1B FKBP6 TRANK1 RREB1 POLE	1.67e-03	483	15	6	HP:0000739
HumanPheno	Abnormal testis morphology	ZMYM2 RSPO2 BAZ1B FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3	1.69e-03	1129	15	9	HP:0000035
HumanPheno	Spinal dysraphism	BAZ1B FKBP6 RREB1 CPLANE1	1.71e-03	186	15	4	HP:0010301
HumanPheno	Non-obstructive azoospermia	ZMYM2 RSPO2 BAZ1B FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3	1.72e-03	1132	15	9	HP:0011961
HumanPheno	Abnormality of the tongue	RSPO2 BAZ1B MFN2 FKBP6 TRANK1 CPLANE1	1.73e-03	486	15	6	HP:0000157
HumanPheno	Anomaly of the limb diaphyses	RSPO2 BAZ1B FKBP6 HERC2 CPLANE1	1.73e-03	322	15	5	HP:0006504
HumanPheno	Autistic behavior	GABRG2 ZMYM2 BAZ1B FKBP6 HERC2 RREB1 ZMYM3	1.75e-03	678	15	7	HP:0000729
HumanPheno	Poor motor coordination	GABRG2 MFN2 HERC2	1.77e-03	85	15	3	HP:0002275
HumanPheno	Flat cornea	BAZ1B FKBP6	1.81e-03	22	15	2	HP:0007720
HumanPheno	Elfin facies	BAZ1B FKBP6	1.81e-03	22	15	2	HP:0004428
HumanPheno	Impairment in personality functioning	GABRG2 ZMYM2 BAZ1B FKBP6 TRANK1 HERC2 RREB1 POLE ZMYM3	1.83e-03	1141	15	9	HP:0031466
HumanPheno	Abnormality of the ankle	GABRG2 BAZ1B MFN2 FKBP6	1.93e-03	192	15	4	HP:0003028
HumanPheno	Azoospermia	ZMYM2 RSPO2 BAZ1B FKBP6 HERC2 RREB1 CPLANE1 POLE ZMYM3	2.03e-03	1157	15	9	HP:0000027
MousePheno	abnormal forehead shape	BAZ1B LHX2 APAF1	5.94e-06	17	30	3	MP:0030045
MousePheno	abnormal forehead morphology	BAZ1B LHX2 APAF1	1.75e-05	24	30	3	MP:0030031
MousePheno	abnormal embryonic/fetal subventricular zone morphology	ITGB8 APAF1 NOSIP	9.00e-05	41	30	3	MP:0004274
Domain	DUF3504	ZMYM2 ZMYM4 ZMYM3	7.14e-08	5	37	3	PF12012
Domain	DUF3504	ZMYM2 ZMYM4 ZMYM3	7.14e-08	5	37	3	IPR021893
Domain	zf-FCS	ZMYM2 ZMYM4 ZMYM3	2.49e-07	7	37	3	PF06467
Domain	Znf_MYM	ZMYM2 ZMYM4 ZMYM3	2.49e-07	7	37	3	IPR010507
Domain	TRASH_dom	ZMYM2 ZMYM4 ZMYM3	3.98e-07	8	37	3	IPR011017
Domain	TRASH	ZMYM2 ZMYM4 ZMYM3	3.98e-07	8	37	3	SM00746
Domain	zf-H2C2_2	ZNF599 OVOL1	3.42e-04	14	37	2	PF13465
Domain	C2H2_Znf_fam	OVOL1 ZSCAN5A	1.03e-03	24	37	2	IPR027775
Domain	-	TRIM46 BAZ1B PML NOSIP ZFYVE21	1.82e-03	449	37	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRIM46 BAZ1B PML NOSIP ZFYVE21	2.00e-03	459	37	5	IPR013083
Domain	Znf_C2H2-like	ZNF599 OVOL1 RREB1 ZNF334 ZSCAN5A ZFR2	4.41e-03	796	37	6	IPR015880
Domain	Znf_C2H2	ZNF599 OVOL1 RREB1 ZNF334 ZSCAN5A ZFR2	4.66e-03	805	37	6	IPR007087
Domain	ZnF_C2H2	ZNF599 OVOL1 RREB1 ZNF334 ZSCAN5A ZFR2	4.75e-03	808	37	6	SM00355
Domain	EGF_extracell	LRP1B ITGB8	6.29e-03	60	37	2	IPR013111
Domain	EGF_2	LRP1B ITGB8	6.29e-03	60	37	2	PF07974
Domain	BBOX	TRIM46 PML	8.24e-03	69	37	2	SM00336
Domain	LIM	LHX2 FHL2	8.24e-03	69	37	2	PF00412
Domain	-	LHX2 FHL2	8.47e-03	70	37	2	2.10.110.10
Domain	LIM_DOMAIN_2	LHX2 FHL2	8.71e-03	71	37	2	PS50023
Domain	Znf_LIM	LHX2 FHL2	8.71e-03	71	37	2	IPR001781
Domain	LIM_DOMAIN_1	LHX2 FHL2	8.71e-03	71	37	2	PS00478
Domain	LIM	LHX2 FHL2	8.71e-03	71	37	2	SM00132
Domain	zf-B_box	TRIM46 PML	8.95e-03	72	37	2	PF00643
Domain	-	VWA3A ITGB8	9.43e-03	74	37	2	3.40.50.410
Domain	-	ZNF599 OVOL1 RREB1 ZNF334 ZSCAN5A	1.04e-02	679	37	5	3.30.160.60
Domain	ZF_BBOX	TRIM46 PML	1.10e-02	80	37	2	PS50119
Domain	EGF	LRP1B ITGB8 TMEFF2	1.12e-02	235	37	3	SM00181
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZMYM2 RREB1 ZSCAN5A ZMYM4 ZMYM3 PML	4.05e-09	125	37	6	32891193
Pubmed	Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198.	ZMYM2 ZMYM3 PML	1.11e-08	5	37	3	25133527
Pubmed	Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.	TRIM46 BAZ1B OVOL1 RREB1	7.92e-07	67	37	4	23263486
Pubmed	Cloning and mapping of members of the MYM family.	ZMYM4 ZMYM3	3.30e-06	3	37	2	10486218
Pubmed	ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML.	ZMYM2 PML	3.30e-06	3	37	2	17027752
Pubmed	Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins.	ZMYM2 ZMYM4	3.30e-06	3	37	2	32439918
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZMYM2 BAZ1B ZMYM4 ZMYM3	4.44e-06	103	37	4	32744500
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	ZMYM2 FHL2 ZMYM4 ZMYM3 PML	8.36e-06	262	37	5	36880596
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ZMYM2 BAZ1B RREB1 ZMYM3 PML	1.34e-05	289	37	5	23752268
Pubmed	Human transcription factor protein interaction networks.	ZMYM2 BAZ1B LHX2 HERC2 RREB1 ZMYM4 ZMYM3 PML NOSIP	1.43e-05	1429	37	9	35140242
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	ZMYM2 RREB1 ZMYM3	1.52e-05	45	37	3	21258344
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	ZMYM2 BAZ1B RREB1 ZMYM4 PML	3.31e-05	349	37	5	25665578
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZMYM2 BAZ1B ZMYM4 ZMYM3 PML NOSIP	3.39e-05	588	37	6	38580884
Pubmed	Interaction network of human early embryonic transcription factors.	ZMYM2 BAZ1B RREB1 ZMYM4 ZMYM3	3.40e-05	351	37	5	38297188
Pubmed	ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development.	ZMYM2 GC	3.95e-05	9	37	2	37395395
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZMYM2 BAZ1B HERC2 RREB1 ZMYM4 ZMYM3	4.08e-05	608	37	6	36089195
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	ZMYM2 ZMYM4 ZMYM3	6.82e-05	74	37	3	29795351
Pubmed	Regulation of LSD1 histone demethylase activity by its associated factors.	ZMYM2 RREB1	7.22e-05	12	37	2	16140033
Pubmed	ZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers.	ZMYM2 ZMYM4	8.53e-05	13	37	2	18806873
Pubmed	An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.	ZMYM2 ZMYM3	8.53e-05	13	37	2	16079794
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ZMYM2 BAZ1B ZMYM4 PML NOSIP	1.03e-04	444	37	5	34795231
Pubmed	Genome-wide association of body fat distribution in African ancestry populations suggests new loci.	LHX2 RREB1	1.31e-04	16	37	2	23966867
Pubmed	Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.	PML APAF1	1.67e-04	18	37	2	26334721
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	ZMYM2 ZMYM3	1.67e-04	18	37	2	12493763
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZMYM2 RREB1 ZSCAN5A ZMYM4 ZMYM3	1.71e-04	495	37	5	27705803
Pubmed	Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses.	PLA2G2A GBP2	1.86e-04	19	37	2	16705022
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TRANK1 HERC2 ZMYM3	1.87e-04	104	37	3	9205841
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZMYM2 BAZ1B OVOL1 ZNF334 ZSCAN5A PML	1.94e-04	808	37	6	20412781
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	ZMYM2 BAZ1B ZMYM4	1.98e-04	106	37	3	19394292
Pubmed	Characterization of a novel Lbx1 mouse loss of function strain.	LHX2 FHL2	3.52e-04	26	37	2	34906895
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZMYM2 BAZ1B RREB1 FHL2 ZSCAN5A ZMYM4 ZMYM3	3.76e-04	1294	37	7	30804502
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	ZMYM4 ZMYM3	4.39e-04	29	37	2	21834987
Pubmed	Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.	GBP2 APAF1	4.39e-04	29	37	2	33278357
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZMYM2 BAZ1B RREB1 ZMYM4 PML NOSIP	4.71e-04	954	37	6	36373674
Pubmed	Defining developmental diversification of diencephalon neurons through single cell gene expression profiling.	RSPO2 LHX2	5.02e-04	31	37	2	30872278
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ZMYM2 ZMYM4 ZMYM3	5.49e-04	150	37	3	28242625
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	BAZ1B FKBP6	6.41e-04	35	37	2	11013070
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	ZMYM2 ZMYM4 PML	7.49e-04	167	37	3	20362541
Pubmed	Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.	BAZ1B FKBP6	7.56e-04	38	37	2	11779826
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	BAZ1B FHL2 POLE APAF1 NOSIP	8.54e-04	704	37	5	29955894
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	BAZ1B LHX2 OVOL1 FHL2 ZMYM3	8.82e-04	709	37	5	22988430
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	POLE PML APAF1	9.16e-04	179	37	3	19074885
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	ZMYM2 BAZ1B ZMYM4 ZMYM3	9.33e-04	411	37	4	35182466
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZMYM2 RREB1 ZMYM4 ZMYM3	9.93e-04	418	37	4	34709266
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZMYM2 RREB1 ZMYM4 ZMYM3 PML NOSIP	1.01e-03	1103	37	6	34189442
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	HERC2 ZMYM4 NOSIP ZFYVE21	1.01e-03	420	37	4	28065597
Interaction	ZMYM4 interactions	ZMYM2 LHX2 FHL2 ZSCAN5A ZMYM4 ZMYM3 PML	2.33e-08	171	37	7	int:ZMYM4
Interaction	ZSCAN5A interactions	ZMYM2 ZSCAN5A ZMYM4 ZMYM3	6.79e-07	38	37	4	int:ZSCAN5A
Interaction	ZMYM3 interactions	ZMYM2 ZSCAN5A ZMYM4 ZMYM3 PML	4.94e-06	137	37	5	int:ZMYM3
Interaction	ZMYM2 interactions	ZMYM2 RREB1 ZSCAN5A ZMYM4 ZMYM3 PML	9.16e-06	271	37	6	int:ZMYM2
Interaction	RCOR3 interactions	ZMYM2 RREB1 FHL2 ZSCAN5A ZMYM3	1.49e-05	172	37	5	int:RCOR3
Interaction	HDAC3 interactions	ZMYM2 OVOL1 RREB1 ZSCAN5A ZMYM3 PML	2.07e-05	313	37	6	int:HDAC3
Interaction	ZNF280B interactions	ZMYM2 PML	4.90e-05	6	37	2	int:ZNF280B
Interaction	BLM interactions	ZMYM2 LHX2 HERC2 RREB1 PML	7.19e-05	239	37	5	int:BLM
Interaction	HMG20B interactions	ZMYM2 RREB1 FHL2 ZMYM3	7.23e-05	122	37	4	int:HMG20B
Interaction	ARID3A interactions	ZMYM2 LHX2 HERC2 PML	7.23e-05	122	37	4	int:ARID3A
Interaction	ZSCAN21 interactions	ZMYM2 LRP1B ZMYM4 PML	8.72e-05	128	37	4	int:ZSCAN21
Interaction	ZBTB5 interactions	ZMYM2 HERC2 PML	9.90e-05	49	37	3	int:ZBTB5
Interaction	HNF4A interactions	ZMYM2 RREB1 ZMYM4 ZMYM3 PML	1.39e-04	275	37	5	int:HNF4A
Interaction	RCOR2 interactions	ZMYM2 ZSCAN5A ZMYM3	1.81e-04	60	37	3	int:RCOR2
Interaction	GMEB2 interactions	LHX2 FHL2 PML	1.81e-04	60	37	3	int:GMEB2
Interaction	RCOR1 interactions	ZMYM2 RREB1 FHL2 ZSCAN5A ZMYM4 ZMYM3	2.57e-04	494	37	6	int:RCOR1
Interaction	PIAS4 interactions	ZMYM2 HERC2 RREB1 PML	2.78e-04	173	37	4	int:PIAS4
Interaction	KLF8 interactions	ZMYM2 BAZ1B RREB1 ZMYM4 ZMYM3	3.19e-04	329	37	5	int:KLF8
GeneFamily	Zinc fingers MYM-type	ZMYM2 ZMYM4 ZMYM3	4.66e-08	6	25	3	86
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF599 OVOL1 RREB1 ZNF334 ZSCAN5A	2.67e-03	718	25	5	28
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM46 PML	7.58e-03	95	25	2	59
Coexpression	ATF2_S_UP.V1_UP	LHX2 OVOL1 ZFR2 PML APAF1	7.40e-06	193	37	5	M2682
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWA3A LHX2 TINAG ITGB8	1.44e-05	179	37	4	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	GBP2 TRANK1 ITGB8 PML	1.57e-05	183	37	4	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GBP2 FHL2 LRP1B ZFYVE21	1.82e-05	190	37	4	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD8+_T_naive\|URO / Disease, condition lineage and cell class	ZNF599 ITGB8 ZFR2 NOSIP	2.14e-05	198	37	4	c07426d4119b53e58eb5f448ae364f47cac1fc5c
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GBP2 FHL2 LRP1B ZFYVE21	2.19e-05	199	37	4	a207b4891881149d4c50721310690fd794157723
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VWA3A RSPO2 LRP1B TMEFF2	2.23e-05	200	37	4	7b845aabfbdfe893acc9334a5707833761bed60b
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VWA3A RSPO2 LRP1B TMEFF2	2.23e-05	200	37	4	e3051dcf9b5c8e4dc71a8080b7a7aafea46f2b2b
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VWA3A RSPO2 LRP1B TMEFF2	2.23e-05	200	37	4	0638273fc0910f47fe7a0b6d9a8639b0e9976d13
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VWA3A RSPO2 LRP1B TMEFF2	2.23e-05	200	37	4	1ce9599cc9d8158e8842ca56f35fa7809c234849
Drug	Chloramphenicol [56-75-7]; Up 200; 12.4uM; PC3; HT_HG-U133A	PLA2G2A GBP2 RREB1 ITGB8 PML APAF1	7.45e-07	198	37	6	5047_UP
Disease	Uveal Melanoma	HERC2 RREB1 LRP1B	4.07e-05	53	37	3	EFO_1000616
Disease	Williams Syndrome	BAZ1B FKBP6	4.26e-05	8	37	2	C0175702
Disease	Hepatic Encephalopathy	GABRG2 GC	1.18e-04	13	37	2	C0019151
Disease	Hepatic Coma	GABRG2 GC	1.18e-04	13	37	2	C0019147
Disease	Fulminant Hepatic Failure with Cerebral Edema	GABRG2 GC	1.18e-04	13	37	2	C0751197
Disease	Hepatic Stupor	GABRG2 GC	1.18e-04	13	37	2	C0751198
Disease	colorectal cancer (is_implicated_in)	PLA2G2A LRP1B POLE	4.72e-04	121	37	3	DOID:9256 (is_implicated_in)
Disease	hair color	RSPO2 LHX2 OVOL1 HERC2	6.08e-04	311	37	4	EFO_0003924
Disease	hyperuricemia	BAZ1B RREB1	7.88e-04	33	37	2	EFO_0009104
Disease	uric acid measurement	TRIM46 BAZ1B OVOL1 RREB1 ZMYM3	9.37e-04	610	37	5	EFO_0004761
Disease	human immunodeficiency virus infectious disease (is_implicated_in)	PLA2G2A GC	1.10e-03	39	37	2	DOID:526 (is_implicated_in)
Disease	Nodular glomerulosclerosis	MFN2 TINAG	1.22e-03	41	37	2	C0017667
Disease	Diabetic Nephropathy	MFN2 TINAG	1.40e-03	44	37	2	C0011881
Disease	gout	TRIM46 OVOL1 RREB1	1.90e-03	196	37	3	EFO_0004274
Disease	adverse effect, response to xenobiotic stimulus	LRP1B TMEFF2	2.50e-03	59	37	2	EFO_0009658, GO_0009410
Disease	cutaneous melanoma, hair color	HERC2 RREB1	2.76e-03	62	37	2	EFO_0000389, EFO_0003924
Disease	chronic obstructive pulmonary disease (is_implicated_in)	GC LRP1B	2.85e-03	63	37	2	DOID:3083 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCCAFSTDDRFIATC	APAF1	661	O14727
LCDECNKAFHLFCLR	BAZ1B	1201	Q9UIG0
SRDAVKDFDCCCLSL	NOSIP	36	Q9Y314
QLCECDKAAATCFAR	PLA2G2A	106	P14555
ERNCETSCSKDQFRC	LRP1B	3546	Q9NZR2
FKCRNCDDFDFCETC	HERC2	2721	O95714
CECKLNLESELTCFS	LHX2	81	P50458
DDFCKQNSKASSDCC	GBP2	391	P32456
CNFCRDLDLCKDSSF	POLE	2161	Q07864
CFSLNYDLNCDKLCA	MFN2	521	O95140
CSLCDKAFTQRCSLE	OVOL1	176	O14753
DFLDCAESDKFCALS	FKBP6	141	O75344
CVDETFLDSKCFQCD	ITGB8	481	P26012
FIKNELFGDCCLCSF	CPLANE1	186	Q9H799
GKDCASFFCCFEDCR	GABRG2	411	P18507
TARDDFAYCLNCFCD	FHL2	201	Q14192
CNFFDCFSRCDLRVN	DIPK1C	321	Q0P6D2
CTECRATFCNECFKL	TRIM46	186	Q7Z4K8
ASLRCTLGAFCECDF	TOR2A	31	Q8N2E6
LFLCDTNTCKFDGEC	TMEFF2	66	Q9UIK5
FSCKCDSRSLEVDCS	LRTM2	41	Q8N967
ADFWCFECEQLLCAK	PML	136	P29590
CRIENCDSCFSKDFC	RSPO2	96	Q6UXX9
ASLRCTLGAFCECDF	TOR2A	31	Q5JU69
ECKECEKAFCDNFAL	ZNF599	536	Q96NL3
LRFHCKLCECSFNDL	ZFR2	466	Q9UPR6
ECSECEKTFFCQSAL	ZNF334	406	Q9HCZ1
ECKECSAAFAAKRNC	RREB1	791	Q92766
FACDVCEKRFTCNSK	ZSCAN5A	356	Q9BUG6
CDNLSTKNSKFEDCC	GC	286	P02774
VRDFCSEDCCKKFQD	ZMYM2	746	Q9UBW7
FYACSACRDRKDCNF	ZCCHC4	61	Q9H5U6
ECRRCMQCDAKFDFL	ZFYVE21	46	Q9BQ24
AANALCYCDKFCDRE	TINAG	76	Q9UJW2
DCLIKDCNFSDLDIC	TRANK1	416	O15050
VFQFCCRDCCEDFKR	ZMYM3	611	Q14202
LCSDACFSKFRSANN	ZMYM4	466	Q5VZL5
KCCDSFNLLSFAESF	VWA3A	991	A6NCI4