Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

3.76e-075683GO:0030156
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1 LRP1B

2.05e-0516683GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1 LRP1B

4.81e-0521683GO:0030228
GeneOntologyCellularComponentGolgi lumen

DEFA5 HSPG2 MUC3B WNT1 MUC3A MUC5AC

2.07e-06109726GO:0005796
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

1.21e-0428723GO:0002177
MousePhenoectopic manchette

RIMBP3 HOOK1 RIMBP3C RIMBP3B

9.20e-0719574MP:0009377
MousePhenodetached sperm flagellum

RIMBP3 HOOK1 RIMBP3C RIMBP3B

1.41e-0621574MP:0008893
MousePhenoabnormal manchette morphology

RIMBP3 HOOK1 RIMBP3C RIMBP3B

3.27e-0545574MP:0009376
DomainEGF_3

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B OTOG

1.46e-082356910PS50026
DomainEGF-like_dom

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B OTOG

2.53e-082496910IPR000742
DomainEGF

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B

1.99e-07235699SM00181
DomainEGF_1

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B

3.97e-07255699PS00022
DomainEGF-like_CS

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B

4.83e-07261699IPR013032
DomainEGF_2

HSPG2 VLDLR HHIP MUC3B MEGF8 UMODL1 LRP1 MUC3A LRP1B

5.49e-07265699PS01186
DomainSEA

HSPG2 MUC3B UMODL1 MUC3A

1.43e-0623694PS50024
DomainSEA_dom

HSPG2 MUC3B UMODL1 MUC3A

1.43e-0623694IPR000082
DomainEGF_CA

HSPG2 VLDLR MEGF8 UMODL1 LRP1 LRP1B

5.88e-06122696SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 VLDLR MEGF8 UMODL1 LRP1 LRP1B

6.46e-06124696IPR001881
Domain-

VLDLR HHIP LRP1 LRP1B

1.27e-05396942.120.10.30
DomainDUF5050

LRP1 LRP1B

1.35e-052692IPR032485
DomainDUF5050

LRP1 LRP1B

1.35e-052692PF16472
DomainLDLR_class-A_CS

HSPG2 VLDLR LRP1 LRP1B

1.41e-0540694IPR023415
DomainEGF_CA

VLDLR MEGF8 UMODL1 LRP1 LRP1B

1.64e-0586695PF07645
DomainSEA

HSPG2 MUC3B MUC3A

1.71e-0514693SM00200
DomainLdl_recept_b

VLDLR LRP1 LRP1B

1.71e-0514693PF00058
DomainLDLRB

VLDLR LRP1 LRP1B

1.71e-0514693PS51120
DomainLY

VLDLR LRP1 LRP1B

2.13e-0515693SM00135
DomainLDLR_classB_rpt

VLDLR LRP1 LRP1B

2.13e-0515693IPR000033
DomainLdl_recept_a

HSPG2 VLDLR LRP1 LRP1B

2.27e-0545694PF00057
DomainGrowth_fac_rcpt_

HSPG2 VLDLR MEGF8 UMODL1 LRP1 LRP1B

2.39e-05156696IPR009030
Domain-

HSPG2 VLDLR LRP1 LRP1B

2.48e-05466944.10.400.10
Domain6-blade_b-propeller_TolB-like

VLDLR HHIP LRP1 LRP1B

2.48e-0546694IPR011042
DomainLDLRA_1

HSPG2 VLDLR LRP1 LRP1B

2.94e-0548694PS01209
DomainEGF_Ca-bd_CS

VLDLR MEGF8 UMODL1 LRP1 LRP1B

2.94e-0597695IPR018097
DomainLDLRA_2

HSPG2 VLDLR LRP1 LRP1B

3.19e-0549694PS50068
DomainLDrepeatLR_classA_rpt

HSPG2 VLDLR LRP1 LRP1B

3.19e-0549694IPR002172
DomainLDLa

HSPG2 VLDLR LRP1 LRP1B

3.19e-0549694SM00192
DomainEGF_CA

VLDLR MEGF8 UMODL1 LRP1 LRP1B

3.25e-0599695PS01187
DomainASX_HYDROXYL

VLDLR MEGF8 UMODL1 LRP1 LRP1B

3.41e-05100695PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR MEGF8 UMODL1 LRP1 LRP1B

4.51e-05106695IPR000152
DomainSEA

HSPG2 MUC3B UMODL1

7.07e-0522693PF01390
DomainFN3

RIMBP3 UMODL1 OBSL1 RIMBP3C RIMBP3B IGDCC4

9.31e-05199696PS50853
DomainFN3_dom

RIMBP3 UMODL1 OBSL1 RIMBP3C RIMBP3B IGDCC4

1.22e-04209696IPR003961
DomainSp1_fam

SP8 SP9

5.94e-0410692IPR030450
DomainFN3

UMODL1 OBSL1 RIMBP3C RIMBP3B IGDCC4

6.08e-04185695SM00060
DomainTIL

MUC5AC OTOG

8.67e-0412692PF01826
DomainC8

MUC5AC OTOG

8.67e-0412692PF08742
DomainQuinoprot_gluc/sorb_DH

HHIP LRP1

8.67e-0412692IPR011041
DomainPMG

KRTAP13-4 KRTAP13-1

1.02e-0313692PF05287
DomainUnchr_dom_Cys-rich

MUC5AC OTOG

1.02e-0313692IPR014853
DomainC8

MUC5AC OTOG

1.02e-0313692SM00832
DomainKRTAP_PMG

KRTAP13-4 KRTAP13-1

1.02e-0313692IPR007951
DomainEXOIII

REXO1L1P REXO1

1.19e-0314692SM00479
DomainExonuclease_RNaseT/DNA_pol3

REXO1L1P REXO1

1.19e-0314692IPR013520
DomainRNase_T

REXO1L1P REXO1

1.19e-0314692PF00929
DomainTIL_dom

MUC5AC OTOG

1.19e-0314692IPR002919
DomainEGF

HSPG2 VLDLR LRP1 LRP1B

1.22e-03126694PF00008
DomainVWD

MUC5AC OTOG

1.56e-0316692SM00216
DomainVWF_type-D

MUC5AC OTOG

1.56e-0316692IPR001846
DomainVWFD

MUC5AC OTOG

1.56e-0316692PS51233
DomainVWD

MUC5AC OTOG

1.56e-0316692PF00094
DomainRNaseH-like_dom

ZNF862 REXO1L1P REXO1

2.12e-0369693IPR012337
DomainZINC_FINGER_C2H2_1

RLF ZXDC SP8 HIC1 ZNF26 CTCF TUT7 SP9 ZNF778

2.16e-03777699PS00028
DomainWnt

WNT1 WNT2B

2.21e-0319692IPR005817
DomainVWC_out

MUC5AC OTOG

2.21e-0319692SM00215
DomainWnt_CS

WNT1 WNT2B

2.21e-0319692IPR018161
Domainwnt

WNT1 WNT2B

2.21e-0319692PF00110
DomainWNT1

WNT1 WNT2B

2.21e-0319692SM00097
DomainWNT1

WNT1 WNT2B

2.21e-0319692PS00246
DomainZnf_C2H2

RLF ZXDC SP8 HIC1 ZNF26 CTCF TUT7 SP9 ZNF778

2.74e-03805699IPR007087
DomainCT

MUC5AC OTOG

2.96e-0322692SM00041
DomainSH3_9

RIMBP3 RIMBP3C RIMBP3B

3.01e-0378693PF14604
Domain-

RLF ZXDC SP8 HIC1 ZNF26 CTCF SP9 ZNF778

3.47e-036796983.30.160.60
DomainCys_knot_C

MUC5AC OTOG

3.82e-0325692IPR006207
DomainCTCK_2

MUC5AC OTOG

3.82e-0325692PS01225
DomainZnf_C2H2/integrase_DNA-bd

RLF ZXDC SP8 HIC1 ZNF26 CTCF SP9 ZNF778

3.96e-03694698IPR013087
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

3.97e-0386693IPR011511
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

3.97e-0386693PF07653
DomaincEGF

LRP1 LRP1B

4.13e-0326692IPR026823
DomaincEGF

LRP1 LRP1B

4.13e-0326692PF12662
DomainEGF_LAM_2

HSPG2 MEGF8

5.47e-0330692PS50027
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 HOOK1 RIMBP3C RIMBP3B

1.89e-11474419091768
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3B MUC3A MUC5AC

9.25e-09374318163520
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

9.22e-08574317855024
Pubmed

Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning.

SP8 WNT2B SP9

7.70e-07974317509151
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

3.31e-061474317662146
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1 LRP1B

3.31e-061474315082773
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

4.47e-06274215963947
Pubmed

Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

MUC3B MUC3A

4.47e-06274212958310
Pubmed

Plasminogen-dependent internalization of soluble melanotransferrin involves the low-density lipoprotein receptor-related protein and annexin II.

MELTF LRP1

4.47e-06274217570828
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

4.47e-06274223836919
Pubmed

Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.

MUC3B MUC3A

4.47e-06274210973822
Pubmed

MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

MUC3B MUC3A

4.47e-0627429334251
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

VLDLR LRP1

4.47e-06274215327526
Pubmed

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

MUC3B MUC3A

4.47e-0627422393399
Pubmed

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

MUC3B MUC3A

4.47e-06274211289722
Pubmed

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

MUC3B MUC3A

4.47e-06274210405327
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP1 LRP1B

1.20e-052174321337463
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF19 NBPF10 NBPF20

1.20e-052174316079250
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

VLDLR LRP1

1.34e-05374218277139
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LRP1

1.34e-05374218367731
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC3B MUC3A

1.34e-05374210512748
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

VLDLR LRP1

1.34e-05374211931574
Pubmed

The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1).

VLDLR HIC1

1.34e-05374224076391
Pubmed

Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function.

HSPG2 HHIP

2.67e-05474226056142
Pubmed

Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.

AFP WNT1

2.67e-0547423293998
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LRP1

2.67e-05474215863833
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

VLDLR LRP1

2.67e-05474215840700
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

VLDLR LRP1

4.45e-0557428013374
Pubmed

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

WNT1 LRP1B

4.45e-05574220383322
Pubmed

Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway.

RAB9A HOOK1

4.45e-05574215471887
Pubmed

Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

HSPG2 LRP1

4.45e-05574221289173
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

VLDLR LRP1

4.45e-05574230700132
Pubmed

Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

SP8 SP9

4.45e-05574215358670
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

VLDLR LRP1

4.45e-05574212746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

VLDLR LRP1

4.45e-05574218992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

VLDLR LRP1

4.45e-05574223959870
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LRP1

4.45e-05574218685438
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR LRP1 GPR84 LRP1B

6.59e-0510174423382219
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

VLDLR LRP1

6.66e-05674216478678
Pubmed

Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.

KRTAP13-4 KRTAP13-1 KRTAP10-4

8.63e-054074312359730
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LRP1

9.31e-05774212169628
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.

VLDLR LRP1

9.31e-05774223760271
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

VLDLR LRP1

1.24e-04874210380922
Pubmed

Wnt5a controls neurite development in olfactory bulb interneurons.

WNT1 WNT2B

1.24e-04874221539518
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

AFP WNT1 WNT2B

1.59e-044974319562671
Pubmed

The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.

RLF VLDLR

1.59e-04974225857663
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

VLDLR LRP1

1.59e-0497427544347
Pubmed

Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia.

WNT1 WNT2B

1.59e-04974212668639
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

VLDLR LRP1

1.59e-04974220005821
Pubmed

Neighbor of Punc E 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development.

AFP IGDCC4

1.59e-04974222497843
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP1B

2.43e-041174224639464
Pubmed

A cellular and spatial map of the choroid plexus across brain ventricles and ages.

HHIP WNT1 WNT2B

2.76e-045974333932339
Pubmed

Transcription Factors Sp8 and Sp9 Regulate Medial Ganglionic Eminence-Derived Cortical Interneuron Migration.

SP8 SP9

3.43e-041374231001083
Pubmed

Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons.

SP8 SP9

3.43e-041374231070778
Pubmed

Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA.

AFP WNT1

3.43e-04137421794049
Pubmed

Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons.

SP8 SP9

3.43e-041374234014554
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

WNT1 LRP1

3.43e-041374216207730
Pubmed

Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester.

WNT2B MAMLD1

3.43e-041374217848411
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP1

4.00e-041474217389516
Pubmed

Beta-catenin is temporally regulated during normal liver development.

AFP WNT1

4.00e-041474215057752
Pubmed

Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium.

WNT1 WNT2B

4.00e-041474217855431
Pubmed

Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.

WNT1 WNT2B

4.61e-041574215044261
Pubmed

GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.

HHIP MUC5AC

5.26e-041674226932670
Pubmed

Molecular genetic studies of Wnt signaling in the mouse.

WNT1 WNT2B

5.26e-041674210585256
Pubmed

The Wnts.

WNT1 WNT2B

5.26e-04167429889131
Pubmed

c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.

WNT1 WNT2B

5.26e-041674222677559
Pubmed

The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity.

SP8 SP9

5.95e-041774236081908
Pubmed

Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.

SP8 SP9

5.95e-041774217376983
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SCAP N4BP2 IRF2BPL DHTKD1 REXO1L1P REXO1

6.46e-0449374615368895
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC3A MUC5AC

6.68e-041874218834073
Pubmed

Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.

WNT1 WNT2B

6.68e-041874222166339
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LRP1

6.68e-041874210827173
Pubmed

Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.

HHIP WNT2B

6.68e-041874230352852
Pubmed

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.

WNT1 WNT2B

7.46e-041974228834739
Pubmed

Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development.

SP8 SP9

7.46e-041974228981617
Pubmed

Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog.

SP8 SP9

7.46e-041974232234482
Pubmed

Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.

WNT1 WNT2B

7.46e-041974211520664
Pubmed

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

DEFA5 WNT1

8.28e-042074218536717
Pubmed

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.

HIC1 SMOC2

8.28e-042074236542062
Pubmed

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.

WNT1 WNT2B

9.14e-042174217943183
Pubmed

Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.

WNT1 WNT2B

9.14e-042174231914354
Pubmed

Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.

WNT1 WNT2B

1.00e-032274212815618
Pubmed

Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.

HHIP MUC5AC

1.00e-032274220430747
Pubmed

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy.

SP8 WNT1

1.00e-032274233469032
Pubmed

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.

WNT1 WNT2B

1.10e-032374227362799
Pubmed

Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.

PPP2R1B LRP1

1.20e-032474217452356
Pubmed

Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development.

SP8 SP9

1.20e-032474229878134
Pubmed

Directed differentiation of telencephalic precursors from embryonic stem cells.

WNT1 WNT2B

1.30e-032574215696161
Pubmed

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.

PPP2R1B POLR2B

1.30e-032574234004147
Pubmed

Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border.

SP8 WNT1

1.30e-032574216571633
Pubmed

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex.

WNT1 WNT2B

1.30e-032574219149881
Pubmed

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.

HHIP WNT1

1.30e-032574212421714
Pubmed

Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.

SP8 SP9

1.30e-032574223042297
Pubmed

Mammalian SP/KLF transcription factors: bring in the family.

SP8 SP9

1.30e-032574215820306
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SPHKAP TUT7 ACAP3

1.36e-0310274311214970
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

POLR2B REXO1

1.40e-032674233298525
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NBPF19 KCNH6 ZNF862 SLCO6A1

1.56e-0323374437704626
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

WNT1 WNT2B

1.63e-032874220940229
Pubmed

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

WNT1 WNT2B

1.63e-032874224394376
Pubmed

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

SP8 SP9

1.63e-032874232868762
Cytoband2q36

SPHKAP SLC4A3

7.13e-0587422q36
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B

7.87e-0411174322q11.21
Cytoband7q22

MUC3B MUC3A

1.74e-03387427q22
Cytoband21q22.1

KRTAP13-4 KRTAP13-1

1.83e-033974221q22.1
CytobandEnsembl 112 genes in cytogenetic band chr21q22

KRTAP13-4 UMODL1 KRTAP13-1 KRTAP10-4

3.28e-03377744chr21q22
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1 LRP1B

6.66e-0613533634
GeneFamilyCD molecules|Mucins

MUC3B MUC3A MUC5AC

3.05e-0521533648
GeneFamilyNeuroblastoma breakpoint family

NBPF19 NBPF10 NBPF20

4.04e-0523533662
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

RLF ZXDC SP8 HIC1 ZNF26 CTCF ZNF862 SP9 ZNF778

2.16e-0471853928
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP8 SP9

3.00e-049532755
GeneFamilyWnt family|Endogenous ligands

WNT1 WNT2B

1.40e-0319532360
GeneFamilyPhosphoinositide phosphatases

MTMR4 PIP4P2

3.95e-03325321079
GeneFamilyKeratin associated proteins

KRTAP13-4 KRTAP13-1 KRTAP10-4

4.01e-03109533619
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 OBSL1 IGDCC4

1.17e-02161533593
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP WNT1 WNT2B ISM1 PCOLCE2 SMOC2

7.05e-07190736f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP WNT1 WNT2B ISM1 PCOLCE2 SMOC2

7.05e-071907362abeb013bb83c578e67dcb985ba44ca63134950b
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR KCNK3 OBSL1 LRP1 PCOLCE2 SMOC2

7.05e-0719073696a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP WNT1 WNT2B ISM1 PCOLCE2 SMOC2

7.27e-07191736d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HHIP ISM1 LRP1 PCOLCE2 SMOC2

7.73e-07193736d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 HHIP MELTF ISM1 LRP1 PCOLCE2

8.21e-071957360feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 HHIP MELTF ISM1 LRP1 PCOLCE2

8.21e-071957362a6f67875cef140b0e6b8401436719675c6b3665
ToppCellPND01-Mesenchymal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP ISM1 LRP1 PCOLCE2 SMOC2

8.71e-07197736292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP LRP1 PCOLCE2 SMOC2 IGDCC4

1.37e-0518673594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

ZNF26 SCAP RNF103 N4BP2 REXO1

1.40e-05187735d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 ISM1 LRP1 PCOLCE2 SMOC2

1.59e-0519273529bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 ISM1 LRP1 PCOLCE2 SMOC2

1.59e-05192735cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR LRP1 PCOLCE2 SMOC2

1.59e-051927352d9e2262f1342fe17735f21f733c029d1275e955
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 LRP1 IRF2BPL PCOLCE2 SMOC2

1.68e-05194735bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP LRP1 PCOLCE2 SMOC2

1.72e-051957356bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 LRP1 IRF2BPL PCOLCE2 SMOC2

1.72e-05195735690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP LRP1 PCOLCE2 SMOC2

1.72e-05195735a3b468125e48f072255cede7645f6692298ecf54
ToppCellP03-Mesenchymal|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VLDLR HHIP KCNK3 LRP1 PCOLCE2

1.72e-051957356180309c6ae278b996fd98c57461cbc129c028ba
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 LRP1 IRF2BPL PCOLCE2 SMOC2

1.72e-051957355c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCellPND28-Mesenchymal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 ISM1 KCNK3 LRP1 PCOLCE2

1.76e-05196735119265efd2219f328d8152dbee52af8327aec89c
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HHIP ISM1 LRP1 SMOC2

1.76e-05196735b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HHIP ISM1 LRP1 SMOC2

1.76e-05196735787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellMatrixFB|World / shred on cell class and cell subclass (v4)

VLDLR HHIP ISM1 KCNK3 PCOLCE2

1.80e-05197735e325de44e32021a36fffb7b7e88167b46bb051c7
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP LRP1 PCOLCE2 SMOC2

1.80e-0519773506a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellPND03-Mesenchymal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP ISM1 KCNK3 PCOLCE2

1.80e-05197735e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

HHIP SPHKAP PCOLCE2 SMOC2 IGDCC4

1.80e-05197735a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR HHIP LRP1 PCOLCE2 SMOC2

1.80e-05197735d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIC1 ISM1 LRP1 PCOLCE2 IGDCC4

1.89e-051997359672230aa0bc6a7289050c955f5154ca183a5159
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIC1 ISM1 LRP1 PCOLCE2 IGDCC4

1.89e-05199735e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCellIPF-Epithelial-PNEC|World / Disease state, Lineage and Cell class

KCNH6 HOOK1 SPHKAP KCNK3

1.42e-04161734133833729ba8b6d3eef326590ca7476b17602cbb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NBPF19 GPR26 SPHKAP MAMLD1

1.75e-04170734985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 KCNK3 LRP1 LRP1B

1.75e-041707345570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 HIC1 MAMLD1 SMOC2

1.79e-04171734972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 HIC1 MAMLD1 SMOC2

1.79e-041717342a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

MEGF8 ZNF862 NBPF10 MUC5AC

1.83e-04172734f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CTCF KCNK3 NLRP2 PIP4P2

1.83e-04172734da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SP8 HOOK1 WNT1 MUC5AC

1.91e-04174734e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SP8 HOOK1 WNT1 MUC5AC

1.91e-04174734ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

1.91e-0417473468a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NBPF10 KCNK3 LRP1 MSTN

1.95e-0417573412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNFRSF25 RNF103 NBPF10 NBPF20

1.95e-04175734a3f8c54c77bce9b035a4835945ab341909be4946
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMODL1 AFP PCOLCE2 ACAP3

2.00e-041767348e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

HHIP HIC1 ISM1 LRP1

2.08e-04178734142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MELTF PCOLCE2 SMOC2 TRIM38

2.08e-04178734c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KCNH6 SPHKAP SMOC2 MUC3A

2.17e-0418073457689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HHIP KCNK3 LRP1 SMOC2

2.22e-04181734c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HHIP KCNK3 LRP1 SMOC2

2.22e-04181734c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HHIP SPHKAP ISM1 LRP1

2.32e-041837347eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Calb2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

WNT2B PSMB11 MSTN

2.35e-04737338e8d06bd4404fe6fda753e7adedc2f2150524750
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Calb2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

WNT2B PSMB11 MSTN

2.35e-047373348a499fa03d736310d09b01c8889db5288e9b2da
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT2B LRP1 PCOLCE2 SMOC2

2.36e-041847343bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

HHIP ISM1 KCNK3 MSTN

2.36e-0418473486a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT2B LRP1 PCOLCE2 SMOC2

2.41e-0418573433cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HHIP SPHKAP ISM1 SMOC2

2.41e-041857346712512100ccef456d2e2bd201d0987986c92ac9
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT2B LRP1 PCOLCE2 SMOC2

2.41e-041857349954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPHKAP ISM1 LRP1 SMOC2

2.41e-041857343b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SP8 SPHKAP SP9 RIMBP3C

2.41e-041857346e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP LRP1 PCOLCE2 SMOC2

2.41e-04185734785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP LRP1 PCOLCE2 SMOC2

2.41e-0418573497a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|390C / Donor, Lineage, Cell class and subclass (all cells)

TNFRSF25 PPP2R1B C10orf95 NUP205

2.46e-04186734064b6047215597465bb51a8a1547ef5a226552f9
ToppCellnormal_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ZNF26 RNF103 OBSL1 REXO1

2.51e-04187734a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ISM1 LRP1 PCOLCE2 SMOC2

2.57e-04188734c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HHIP LRP1 PCOLCE2 SMOC2

2.57e-04188734ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

VLDLR HHIP ISM1 LRP1

2.57e-041887343f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ISM1 LRP1 PCOLCE2 SMOC2

2.57e-041887341cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TNFRSF25 PPP2R1B C10orf95 NUP205

2.57e-04188734b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.57e-041887347191087d8754f5e8700e3d744cd920ee26db1e57
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

VLDLR HHIP ISM1 PCOLCE2

2.57e-041887346740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HHIP ISM1 PCOLCE2

2.62e-04189734c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR ISM1 LRP1 PCOLCE2

2.62e-04189734bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HHIP ISM1 PCOLCE2

2.62e-041897342a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR LRP1 PCOLCE2 SMOC2

2.62e-041897346e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.62e-04189734bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR ISM1 LRP1 PCOLCE2

2.62e-0418973440cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCOLCE2 PSMB11 SMOC2

2.62e-04189734dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 LRP1 PCOLCE2 SMOC2

2.62e-041897342a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 HHIP ISM1 PCOLCE2

2.62e-041897345a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HHIP ISM1 KCNK3 LRP1

2.62e-0418973445e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HHIP LRP1 PCOLCE2 SMOC2

2.67e-04190734efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HHIP ISM1 KCNK3 LRP1B

2.67e-04190734938d1f66094b1c94606e0d40213a39e5112f3322
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.67e-04190734f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NBPF19 GPR26 SPHKAP MAMLD1

2.67e-041907341bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.67e-04190734c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.67e-0419073447077579496c5340e99f61499427a3a36b566da3
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LRP1 PCOLCE2 SMOC2

2.72e-041917342b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.72e-04191734a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR HIC1 ISM1 PCOLCE2

2.72e-041917348a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

VLDLR LRP1 PCOLCE2 SMOC2

2.72e-04191734e7c605b56934d1383237c1f946dbccef25d91368
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 LRP1 PCOLCE2 SMOC2

2.72e-0419173444631226f59364098a7dd58058e6970a75441009
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.72e-0419173419c67a812b8ce97472d316acd15aeefe8736000d
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHIP ISM1 SMOC2 SLC4A3

2.72e-0419173424dc77ee8de01b42559f92721655f4281b114e17
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 LRP1 PCOLCE2 SMOC2

2.72e-04191734f892f725a32e704cd18fec2f6d1db82993e7e79a
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR ISM1 LRP1 PCOLCE2

2.72e-04191734997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 PCOLCE2 SMOC2

2.78e-04192734671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 VLDLR PCOLCE2 SMOC2

2.78e-04192734c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ISM1 LRP1 SMOC2

2.78e-04192734a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR ISM1 LRP1 PCOLCE2

2.78e-0419273425492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LRP1 PCOLCE2 SMOC2

2.78e-041927347b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ISM1 LRP1 SMOC2

2.78e-04192734eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LRP1 PCOLCE2 SMOC2

2.78e-0419273432acd89617934016cd135d2cc797e8e79ae1b37f
Diseaseshort QT syndrome (implicated_via_orthology)

KCNH6 SLC4A3

1.34e-053632DOID:0050793 (implicated_via_orthology)
DiseaseHypospadias

HHIP MAMLD1

4.47e-055632C0848558
Diseaseendodermal sinus tumor (is_marker_for)

AFP WNT2B

4.47e-055632DOID:1911 (is_marker_for)
Diseasediverticular disease

SP8 HHIP KCNK3 SMOC2 DHTKD1

1.51e-04236635EFO_0009959
DiseaseCorneal astigmatism

LINC02881 KCNK3 SMOC2

6.06e-0477633EFO_1002040
Diseasemigraine disorder, pulse pressure measurement

HIC1 LRP1

1.41e-0326632EFO_0005763, MONDO_0005277
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

MUC3B MUC3A PIP4P2

1.70e-03110633EFO_0803335
Diseasemuscular atrophy (biomarker_via_orthology)

MTMR4 MSTN

1.76e-0329632DOID:767 (biomarker_via_orthology)
Diseaseresponse to angiotensin receptor blocker

WNT2B KCNK3

1.88e-0330632EFO_0010735

Protein segments in the cluster

PeptideGeneStartEntry
SYTCQCRTTRDATPS

UMODL1

531

Q5DID0
RTSACGLFSVCYPRA

PPP2R1B

156

P30154
SASYDLRERLCPGSA

SLC4A3

226

P48751
ERPFQCSLCSYASRD

CTCF

376

P49711
DSCYSERLDRTASPS

ACAP3

371

Q96P50
TTPAERGRSSLYCSD

DHTKD1

371

Q96HY7
YCALPRSRASSESEL

ATXN7L2

341

Q5T6C5
RLTCLPEAASASCSY

IGDCC4

1196

Q8TDY8
RTPSGLYLGTCERCS

HSPG2

1146

P98160
SLRTPFYRGSDCCLL

RAB9A

71

P51151
DCFAPACSRSLDSTR

RIMBP3B

286

A6NNM3
DCFAPACSRSLDSTR

RIMBP3C

286

A6NJZ7
SCRRTGAACLPFYSA

GRSF1

21

Q12849
CACSDTSGPTMRYLR

NUP205

1071

Q92621
QLRRCGPSDAGTYSC

OBSL1

1686

O75147
SPTCSSREYICASDG

LRP1B

3591

Q9NZR2
GELLRPYRCASCDKS

HIC1

501

Q14526
GRYSDTPSRRCLCSG

KCNK3

351

O14649
CGDRSDESASCAYPT

LRP1

961

Q07954
DESRRGACSYTCSPL

KCNH6

286

Q9H252
QLYASCTLCSRRPDE

GPR26

151

Q8NDV2
VSSSRRQSCYLCDLP

IRF2BPL

6

Q9H1B7
LETSGPTCRCYSTDT

MUC3A

3196

Q02505
GTCQGSSPSDRRDCY

MEGF8

2406

Q7Z7M0
SCRELSRLGPCSFAE

NLRP2

246

Q9NX02
CSSSEPVRLAYCRGN

MUC5AC

5546

P98088
CRRTGTLEGNYCSSD

PCOLCE2

301

Q9UKZ9
DTRSSCGSYVACPAS

PSMB11

66

A5LHX3
YCRTGRCATRESLSG

DEFA5

66

Q01523
CTCSFDRIRGRPYTT

GPR84

166

Q9NQS5
EATPRRLLSYGCCSK

MTMR4

921

Q9NYA4
EYPTRRTLCSSDRGC

P2RX7

121

Q99572
TESCYFPAQRGSACR

REXO1L1P

171

Q8IX06
PSCDATARGTEIRSY

MAMLD1

756

Q13495
SDLSYSSRVCLPGSC

KRTAP10-4

6

P60372
FCRPTYLASRSCQSS

KRTAP13-1

146

Q8IUC0
CSPSTCQLRSSLYRD

KRTAP13-4

36

Q3LI77
ACSDTGACTPARSFL

HOOK1

691

Q9UJC3
TGTFNCSSDPRYCRR

RNF103

151

O00237
CGRSRDSPGYDFSCL

SCAP

901

Q12770
TRSCGYACTATESRT

ISM1

241

B1AKI9
YACTATESRTCDRPN

ISM1

246

B1AKI9
CTSSYANRRPCFSSL

AFP

501

P02771
GQTRFRPDSCATTDC

OTOG

2291

Q6ZRI0
ETSGPACRCYSTDTH

MUC3B

1111

Q9H195
RTCCRCGTEYLVSSS

REXO1

971

Q8N1G1
SSSGLCKSDSCLYRR

SPHKAP

1281

Q2M3C7
SSRRFTAFPCVLGCE

TRIM38

326

O00635
AGETSYSESLCRLCR

MELTF

176

P08582
DSLDRCYSTPSSCLE

NBPF10

1516

Q6P3W6
DSLDRCYSTPSSCLE

NBPF10

2736

Q6P3W6
DSLDRCYSTPSSCLE

NBPF19

1001

A0A087WUL8
DSLDRCYSTPSSCLE

NBPF19

2221

A0A087WUL8
DSLDRCYSTPSSCLE

NBPF19

3441

A0A087WUL8
DSLDRCYSTPSSCLE

NBPF20

901

P0DPF2
DSLDRCYSTPSSCLE

NBPF20

2121

P0DPF2
DSLDRCYSTPSSCLE

NBPF20

3341

P0DPF2
DSLDRCYSTPSSCLE

NBPF20

4486

P0DPF2
SLDRCYSTPSSCLEL

NBPF20

4656

P0DPF2
DCFAPACSRSLDSTR

RIMBP3

286

Q9UFD9
STESRCCRYPLTVDF

MSTN

276

O14793
SSVGSALPRRRCCAY

PIP4P2

181

Q8N4L2
AYTGECRSCLENSSR

POLR2B

216

P30876
CRCSSSIYSSICGRD

SLCO6A1

506

Q86UG4
SECSRLCRNGYCTPT

HHIP

606

Q96QV1
ARSARRYSGRATCDC

SP9

296

P0CG40
SSARRYSGRATCDCP

SP8

321

Q8IXZ3
RGAPLCSYRTSCAGS

C10orf95

176

Q9H7T3
CTVCGYRCSSPERTR

LINC02881

76

B7Z368
CTRDRSLDYSSCGEV

ZNF778

191

Q96MU6
PVEGCCARFSARSSL

ZXDC

421

Q2QGD7
GYSSESSICASKRPC

RLF

1041

Q13129
PLCASDGRTFLSRCE

SMOC2

51

Q9H3U7
SRRDTDCGTCLPGFY

TNFRSF25

156

Q93038
RRCACAASSDESPGS

TTC32

36

Q5I0X7
TSSGEFRCISRDCPG

nan

16

Q0VFX4
CSACREYPSIRDKRS

ZNF862

161

O60290
GSIESCTCDYRRRGP

WNT1

146

P04628
TGERPYECSLCERAF

ZNF26

421

P17031
LPDCSLRLYGSSCSR

TUT7

331

Q5VYS8
GELSVCSCDPYTRGR

WNT2B

161

Q93097
PDEFTCSSGRCISRN

VLDLR

156

P98155
LCAYSCEDRSTSPRD

N4BP2

596

Q86UW6