Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 RGPD1 RGPD3

8.90e-06201354GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 RGPD1 RGPD3

9.95e-05361354GO:0019789
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 RALGAPA1 RANBP2 TBC1D15 RASGRF1 MYO9A CYTH1 DOCK9 RGPD1 RGS2 RGPD3 RPGR

1.73e-0450713512GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 RALGAPA1 RANBP2 TBC1D15 RASGRF1 MYO9A CYTH1 DOCK9 RGPD1 RGS2 RGPD3 RPGR

1.73e-0450713512GO:0030695
GeneOntologyMolecularFunctiontranslation elongation factor activity

EIF5A2 EIF5AL1 EIF5A

3.17e-04201353GO:0003746
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD1 RGPD3

3.62e-04501354GO:0003755
GeneOntologyMolecularFunctioncytoskeletal protein binding

TPR KIF13B KLHL2 KIF6 PSG5 MYO9A ARPC1A GC SAXO1 EPB41L4A RGS2 KPTN ALMS1 LMO7 TLN1 ANKRD1 SYNE2 MACF1

4.40e-04109913518GO:0008092
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD1 RGPD3

4.53e-04531354GO:0016859
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 RALGAPA1 RANBP2 TBC1D15 MYO9A RGPD1 RGS2 RGPD3

6.30e-042791358GO:0005096
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD1 RGPD3

2.22e-0791364GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD1 RGPD3

3.68e-07101364GO:1903301
GeneOntologyBiologicalProcesspositive regulation of translational termination

EIF5A2 EIF5AL1 EIF5A

1.12e-0641363GO:0045905
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD1 RGPD3

1.23e-06131364GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD1 RGPD3

1.72e-06141364GO:1903299
GeneOntologyBiologicalProcesspositive regulation of translational elongation

EIF5A2 EIF5AL1 EIF5A

2.78e-0651363GO:0045901
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RANBP2 RGPD1 RGPD3

8.07e-06201364GO:0006607
GeneOntologyBiologicalProcessregulation of translational termination

EIF5A2 EIF5AL1 EIF5A

2.29e-0591363GO:0006449
GeneOntologyBiologicalProcessregulation of translational elongation

EIF5A2 EIF5AL1 EIF5A

9.68e-05141363GO:0006448
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD1 RGPD3

1.12e-04381364GO:0000413
GeneOntologyBiologicalProcessmesodermal to mesenchymal transition involved in gastrulation

EOMES TASOR

1.29e-0431362GO:0060809
GeneOntologyBiologicalProcessestablishment of epithelial cell polarity

MYO9A CYTH1 FAT1 PARD3

1.67e-04421364GO:0090162
GeneOntologyBiologicalProcesstranslational termination

EIF5A2 EIF5AL1 EIF5A

1.78e-04171363GO:0006415
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 RGPD1 EIF5AL1 RGPD3 EIF5A

1.95e-10141366GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 TPR RANBP2 RGPD1 RGPD3

8.67e-08181365GO:0044615
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD1 RGPD3

1.18e-0781364GO:1990723
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 TPR RANBP2 RGPD1 RGPD3

1.55e-07201365GO:0042405
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANBP2 RGPD1 RGPD3

3.49e-07101364GO:0044614
GeneOntologyCellularComponentinclusion body

RGPD4 TPR RANBP2 XRN2 RGPD1 ZBTB14 RGPD3

2.01e-06901367GO:0016234
GeneOntologyCellularComponentnuclear pore

RGPD4 TPR RANBP2 RGPD1 EIF5AL1 RGPD3 EIF5A

4.37e-061011367GO:0005643
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD1 RGPD3

9.41e-06211364GO:0106068
GeneOntologyCellularComponentnuclear protein-containing complex

RGPD4 TPR SETD1A SIN3B RANBP2 AFF2 AFF3 RGPD1 XRCC1 KMT2E BOD1L2 INO80D IRF9 EIF5AL1 RGPD3 SYNE2 EIF5A SMARCD1 SMARCD2 SMARCD3 BOD1L1 HNRNPR

7.91e-05137713622GO:0140513
GeneOntologyCellularComponentbrahma complex

SMARCD1 SMARCD2 SMARCD3

9.30e-05141363GO:0035060
GeneOntologyCellularComponentinhibin-betaglycan-ActRII complex

ACVR2A TGFBR3

1.26e-0431362GO:0034673
GeneOntologyCellularComponentSet1C/COMPASS complex

SETD1A BOD1L2 BOD1L1

1.42e-04161363GO:0048188
GeneOntologyCellularComponentsuper elongation complex

AFF2 AFF3

6.20e-0461362GO:0032783
GeneOntologyCellularComponentphotoreceptor distal connecting cilium

SPATA7 RPGR

8.64e-0471362GO:0120206
GeneOntologyCellularComponentSWI/SNF complex

SMARCD1 SMARCD2 SMARCD3

9.62e-04301363GO:0016514
GeneOntologyCellularComponentnuclear envelope

RGPD4 TPR RANBP2 RGPD1 CLCC1 EIF5AL1 RIF1 LMO7 RGPD3 SYNE2 EIF5A

1.10e-0356013611GO:0005635
GeneOntologyCellularComponentciliary basal body

CYLD SPATA7 IFT140 SAXO1 ALMS1 RPGR

1.76e-031951366GO:0036064
GeneOntologyCellularComponentnuclear membrane

RGPD4 TPR RANBP2 RGPD1 CLCC1 RIF1 RGPD3 SYNE2

2.06e-033491368GO:0031965
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD1 RGPD3

7.08e-06161144MP:0003701
MousePhenoabnormal rod electrophysiology

RGPD4 SPATA7 RANBP2 RGPD1 RGPD3 SYNE2 RPGR

5.26e-051191147MP:0004021
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD1 RGPD3

5.46e-05261144MP:0012058
DomainIF5A_HYPUSINE

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383PS00302
DomainTransl_elong_IF5A_C

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383IPR020189
DomainTransl_elong_IF5A

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383IPR001884
DomaineIF-5a

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383PF01287
DomainSWIB_domain

SMARCD1 SMARCD2 SMARCD3

3.95e-0731383IPR019835
DomainSWIB

SMARCD1 SMARCD2 SMARCD3

3.95e-0731383SM00151
DomainTrans_elong_IF5A_hypusine_site

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383IPR019769
DomaineIF-5a

EIF5A2 EIF5AL1 EIF5A

3.95e-0731383SM01376
DomainRan_BP1

RGPD4 RANBP2 RGPD1 RGPD3

1.35e-06121384PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD1 RGPD3

1.35e-06121384PS50196
DomainRanBD

RGPD4 RANBP2 RGPD1 RGPD3

1.94e-06131384SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD1 RGPD3

1.94e-06131384IPR000156
DomainSWIB

SMARCD1 SMARCD2 SMARCD3

3.90e-0651383PF02201
Domain-

SMARCD1 SMARCD2 SMARCD3

7.77e-06613831.10.245.10
DomainSWIB_MDM2_domain

SMARCD1 SMARCD2 SMARCD3

7.77e-0661383IPR003121
DomainRab_bind

RGPD4 RGPD1 RGPD3

1.35e-0571383PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD1 RGPD3

1.35e-0571383IPR032023
Domain-

RGPD4 RGPD1 RGPD3

4.56e-051013831.10.220.60
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

5.42e-0521382IPR013037
Domain-

AP1B1 AP2B1

5.42e-05213822.60.40.1150
DomainGrip

RGPD4 RGPD1 RGPD3

6.24e-05111383SM00755
DomainGRIP

RGPD4 RGPD1 RGPD3

6.24e-05111383PF01465
DomainGRIP_dom

RGPD4 RGPD1 RGPD3

8.27e-05121383IPR000237
DomainGRIP

RGPD4 RGPD1 RGPD3

8.27e-05121383PS50913
DomainTPR-contain_dom

RGPD4 IFT140 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

1.26e-041501387IPR013026
DomainBod1-like

BOD1L2 BOD1L1

1.62e-0431382IPR026955
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

1.62e-0431382IPR016342
DomainB2-adapt-app_C

AP1B1 AP2B1

1.62e-0431382PF09066
DomainTPR_REGION

RGPD4 IFT140 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

2.27e-041651387PS50293
DomainTPR

RGPD4 IFT140 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

2.27e-041651387PS50005
DomainTranslation_prot_SH3-like

EIF5A2 EIF5AL1 EIF5A

2.49e-04171383IPR008991
DomainRib_L2_dom2

EIF5A2 EIF5AL1 EIF5A

2.97e-04181383IPR014722
Domain-

EIF5A2 EIF5AL1 EIF5A

2.97e-041813832.30.30.30
DomainPP1_inhibitor

PPP1R14C PPP1R14B

3.22e-0441382IPR008025
Domain-

PPP1R14C PPP1R14B

3.22e-04413821.10.150.220
DomainB2-adapt-app_C

AP1B1 AP2B1

3.22e-0441382SM01020
DomainTF_AF4/FMR2

AFF2 AFF3

3.22e-0441382IPR007797
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

3.22e-0441382IPR015151
DomainPP1_inhibitor

PPP1R14C PPP1R14B

3.22e-0441382PF05361
DomainAF-4

AFF2 AFF3

3.22e-0441382PF05110
DomainTPR

RGPD4 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

3.94e-041291386SM00028
DomainTPR_repeat

RGPD4 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

4.64e-041331386IPR019734
DomainAP_beta

AP1B1 AP2B1

5.34e-0451382IPR026739
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

7.97e-0461382IPR012295
Domain-

AP1B1 AP2B1

7.97e-04613823.30.310.10
DomainARM-type_fold

RALGAPA1 DOCK9 WDFY4 RIF1 AP1B1 AP2B1 TELO2 UNC45B PDS5A

9.49e-043391389IPR016024
DomainPH_dom-like

RGPD4 RANBP2 RASGRF1 CYTH1 DOCK9 RGPD1 EPB41L4A WDFY4 TLN1 RGPD3

1.27e-0342613810IPR011993
Domain-

WDFY4 RIF1 AP1B1 AP2B1 TELO2 UNC45B PDS5A

1.33e-0322213871.25.10.10
DomainCH

LMO7 SYNE2 NAV2 MACF1

1.36e-03651384SM00033
DomainCoatomer/calthrin_app_sub_C

AP1B1 AP2B1

1.47e-0381382IPR009028
DomainTPR-like_helical_dom

RGPD4 IFT140 RANBP2 RGPD1 TRANK1 UNC45B RGPD3

1.75e-032331387IPR011990
DomainCH

LMO7 SYNE2 NAV2 MACF1

1.79e-03701384PF00307
DomainHTH_MYB

ZZZ3 MYBL1

1.89e-0391382PS51294
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.89e-0391382PF02883
DomainClathrin_a/b/g-adaptin_app_Ig

AP1B1 AP2B1

1.89e-0391382IPR008152
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.89e-0391382SM00809
DomainMyb_dom

ZZZ3 MYBL1

1.89e-0391382IPR017930
Domain-

LMO7 SYNE2 NAV2 MACF1

1.89e-037113841.10.418.10
DomainCH

LMO7 SYNE2 NAV2 MACF1

2.09e-03731384PS50021
DomainCH-domain

LMO7 SYNE2 NAV2 MACF1

2.31e-03751384IPR001715
DomainCAP_GLY

CYLD KIF13B

2.35e-03101382PF01302
DomainCAP_GLY

CYLD KIF13B

2.35e-03101382SM01052
Domain-

CYLD KIF13B

2.35e-031013822.30.30.190
DomainCAP_GLY_1

CYLD KIF13B

2.35e-03101382PS00845
DomainCAP_GLY_2

CYLD KIF13B

2.35e-03101382PS50245
DomainCAP-Gly_domain

CYLD KIF13B

2.35e-03101382IPR000938
Domain-

RGPD4 RANBP2 RASGRF1 CYTH1 DOCK9 RGPD1 EPB41L4A TLN1 RGPD3

2.52e-0339113892.30.29.30
DomainKOW

EIF5A2 EIF5A

2.85e-03111382IPR005824
DomainKOW

EIF5A2 EIF5A

2.85e-03111382PF00467
DomainARM

AP1B1 AP2B1 UNC45B

3.19e-03401383SM00185
DomainLaminin_G_2

COL11A1 NELL2 FAT1

3.19e-03401383PF02210
DomainCoatomer/clathrin_app_Ig-like

AP1B1 AP2B1

3.41e-03121382IPR013041
PathwayREACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE

EIF5A2 EIF5AL1 EIF5A

4.57e-0651103MM14823
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 TPR RANBP2 RGPD1 RGPD3 GEMIN6

5.73e-06581106MM14736
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD1 RGPD3

9.87e-06181104MM1549
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 TPR RANBP2 RGPD1 RGPD3

1.40e-05401105MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 TPR RANBP2 RGPD1 RGPD3

1.58e-05411105MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

1.78e-05421105MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 TPR RANBP2 RGPD1 RGPD3

2.01e-05431105MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

3.12e-05471105MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 TPR RANBP2 RGPD1 RGPD3

3.83e-05491105MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 TPR RANBP2 RGPD1 RGPD3

4.23e-05501105MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

4.66e-05511105MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 TPR RANBP2 RGPD1 RGPD3

6.73e-05551105MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

8.70e-05581105MM15149
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

1.50e-04651105MM15147
PathwayWP_GLUCOCORTICOID_RECEPTOR_PATHWAY

MGAM PPP1R14C RGS2 TGFBR3 ANKRD1

2.13e-04701105M40042
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 TPR RANBP2 RGPD1 RGPD3

2.60e-04731105MM14948
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 TPR RANBP2 RGPD1 RGPD3

4.47e-04821105MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 TPR RANBP2 RGPD1 RGPD3

4.99e-04841105MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 TPR RANBP2 RGPD1 RGPD3

5.57e-04861105MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 TPR RANBP2 RGPD1 RGPD3

7.57e-04921105MM14951
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SETD1A SIN3B ZZZ3 SMARCD1 SMARCD2 SMARCD3 BOD1L1 TASOR

8.38e-042541108M27131
Pubmed

Human transcription factor protein interaction networks.

CYLD SETD1A SIN3B XRN2 ZNF607 BCORL1 RGPD1 XRCC1 LARP4 INO80D ZBTB14 IRF9 RIF1 FAT1 FBN1 ZZZ3 ALMS1 SYNE2 ZSCAN18 SMARCD1 SMARCD2 PDS5A SMARCD3 ZFR PSME3 SPEN TRAPPC9 FOXI1 HNRNPR

4.16e-1314291392935140242
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-09713949037092
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139438838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-09713947559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139438657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139425187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-09713948603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139423818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139423536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD1 RGPD3

8.47e-097139420682751
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD1 RGPD3

1.69e-088139421670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD1 RGPD3

1.69e-088139427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD1 RGPD3

1.69e-088139421310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD1 RGPD3

1.69e-088139422262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD1 RGPD3

1.69e-088139428745977
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD1 EOMES RGPD3

2.36e-0822139527717094
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139418394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139428100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139417887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-08913949733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD1 RGPD3

3.03e-089139428877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD1 RGPD3

5.04e-0810139427160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD1 RGPD3

5.04e-0810139416332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD1 RGPD3

5.04e-081013948857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD1 RGPD3

5.04e-0810139421859863
Pubmed

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.

EIF5A2 EIF5AL1 EIF5A

6.25e-083139311161802
Pubmed

Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice.

SMARCD1 SMARCD2 SMARCD3

6.25e-083139327125315
Pubmed

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.

EIF5A2 EIF5AL1 EIF5A

6.25e-083139336848144
Pubmed

Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.

EIF5A2 EIF5AL1 EIF5A

6.25e-083139316519677
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD1 RGPD3

7.89e-0811139417069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD1 RGPD3

7.89e-0811139435771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD1 RGPD3

7.89e-0811139434110283
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CYLD KIF13B XRN2 MYO9A BCORL1 RTN3 EIF5AL1 ZZZ3 ALMS1 LMO7 MACF1 SPEN TOP3A HNRNPR

1.13e-075881391438580884
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RANBP2 RGPD1 RGPD3

1.70e-0713139431427429
Pubmed

Interaction network of human early embryonic transcription factors.

SETD1A RANBP2 BCORL1 RGPD1 ZBTB14 ZZZ3 ALMS1 SMARCD1 SMARCD2 SMARCD3 SPEN

1.87e-073511391138297188
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 RGPD1 RGPD3

3.22e-0715139414697343
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CYLD DOCK9 ALMS1 LMO7 TLN1 SYNE2 NAV2 MACF1 PCNX1

3.35e-07225139912168954
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TPR SETD1A SIN3B TBC1D15 ZZZ3 ALMS1 LMO7 TLN1 ZFR BOD1L1 PSME3 PARD3 SPEN

3.49e-075491391338280479
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 TPR RANBP2 RGPD1 RGPD3

4.28e-0738139512791264
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FNBP1 SIN3B RANBP2 XRN2 BCORL1 XRCC1 INO80D ERGIC3 AP1B1 AP2B1 TLN1 SMARCD1 SMARCD2 PDS5A ZFR PSME3 SPEN HNRNPR

4.59e-0711031391834189442
Pubmed

Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.

SMARCD1 SMARCD2 SMARCD3

6.21e-07513939693044
Pubmed

Biological Relevance and Therapeutic Potential of the Hypusine Modification System.

EIF5A2 EIF5AL1 EIF5A

6.21e-075139326037925
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RANBP2 DOCK9 KMT2E PGM1 ALMS1 TLN1 ANKRD1 SYNE2 MACF1 PSME3 PARD3 HNRNPR

8.21e-074971391223414517
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 TPR KLHL2 RANBP2 RGPD1 FBXO30 AP2B1 TLN1 RGPD3 EIF5A SMARCD1 SMARCD2 PDS5A ZFR VPS28 TOP3A MYBL1 HNRNPR

8.88e-0711551391820360068
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TPR FNBP1 RANBP2 TBC1D15 XRN2 ANKLE2 PPP1R14B RIF1 LMO7 NAV2 SMARCD2 SPEN

9.31e-075031391216964243
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

TPR FBXO30 RIF1 ZZZ3 LMO7 TLN1 EIF5A SMARCD1 SMARCD2 ZFR BOD1L1 PSME3

9.91e-075061391230890647
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 TPR SIN3B RANBP2 TBC1D15 BCORL1 RGPD1 ZZZ3 ALMS1 RGPD3 TASOR

1.05e-064181391134709266
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 TPR RANBP2 RGPD1 RIF1 RGPD3

1.32e-0686139637253089
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TPR RANBP2 XRN2 BCORL1 EIF5A2 XRCC1 EIF5AL1 RIF1 ZZZ3 EIF5A PDS5A ZFR BOD1L1 SPEN TASOR HNRNPR

1.47e-069541391636373674
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 CYLD TPR KIF13B SIN3B RANBP2 CYTH1 RGPD1 AP1B1 AP2B1 RGPD3 SYNE2 ZSCAN18 MACF1 ZFR PARD3

1.66e-069631391628671696
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD1 RGPD3

2.16e-067139315710750
Pubmed

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.

SMARCD1 SMARCD2 SMARCD3

2.16e-067139328369036
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

SETD1A SIN3B RIF1 ZZZ3 SMARCD1 SMARCD2 SMARCD3 ZFR BOD1L1 PSME3 TOP3A

2.27e-064531391129656893
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPR RANBP2 XRN2 LARP4 RIF1 AP1B1 AP2B1 TLN1 SYNE2 MACF1 PDS5A ZFR SPEN

2.40e-066531391322586326
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 RANBP2 RGPD1 RIF1 AP1B1 AP2B1 TLN1 RGPD3 PSME3 FYB1

2.60e-063701391022922362
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

RGPD4 TPR RANBP2 RGPD1 LARP4 EIF5AL1 AP1B1 AP2B1 RGPD3 EIF5A ZFR PSME3 SPEN

2.92e-066651391330457570
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPR RANBP2 TBC1D15 XRN2 KRT82 ARPC1A XRCC1 RIF1 LMO7 TLN1 SYNE2 EIF5A MACF1 ZFR SPEN HNRNPR

3.64e-0610241391624711643
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

RALGAPA1 KLHL2 MYO9A CYTH1 DOCK9 XRCC1 LARP4 ZBTB14 RIF1 ERGIC3 AP1B1 TLN1 SMARCD3 RPGR VPS28

4.80e-069251391528986522
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 KIF13B RANBP2 RGPD1 ANKLE2 AP2B1 LMO7 SH3PXD2A RGPD3 SYNE2 ANKRD30A NAV2 MACF1 SMARCD2 ZFR BOD1L1 SPEN TASOR HNRNPR

5.04e-0614421391935575683
Pubmed

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.

SMARCD1 SMARCD2 SMARCD3 TBX5

5.37e-0629139415525990
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RALGAPA1 TPR RANBP2 TBC1D15 MYO9A ANKLE2 CLCC1 TLN1 EIF5A MACF1 PDS5A BOD1L1 PARD3

5.75e-067081391339231216
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

AFF3 WDFY4 EOMES MTF1 C5 CLNK

6.18e-06112139624390342
Pubmed

Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.

SMARCD1 SMARCD2 SMARCD3

7.34e-0610139334716243
Pubmed

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.

AP1B1 AP2B1 UNC45B

7.34e-0610139312383505
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

TPR RANBP2 RIF1 LMO7 TLN1 EIF5A PDS5A BOD1L1 HNRNPR

8.16e-06332139932786267
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

XRN2 XRCC1 AP1B1 AP2B1 LMO7 PDS5A ZFR TOP3A HNRNPR

9.87e-06340139924332808
Pubmed

A protein interaction landscape of breast cancer.

TPR XRN2 VWA8 AP2B1 TLN1 NAV2 SMARCD1 MACF1 SMARCD2 PDS5A SMARCD3 HNRNPR

9.88e-066341391234591612
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

RALGAPA1 CYLD ALMS1 AP1B1 LMO7 SH3PXD2A SMARCD1 PARD3 RASSF4 TRAPPC9

1.33e-054461391024255178
Pubmed

Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm.

SMARCD1 SMARCD2 SMARCD3

1.34e-0512139333723076
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

SMARCD1 SMARCD2 SMARCD3 TBX5

1.46e-0537139424335282
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CYLD SPATA7 AFF2 CLCC1 RIF1 FAT1 PDS5A ZFR PSME3 RPGR PARD3 SPEN TASOR

1.54e-057771391335844135
Pubmed

Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.

EIF5AL1 EIF5A

1.59e-052139237047039
Pubmed

BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A.

SETD1A BOD1L1

1.59e-052139238989615
Pubmed

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

EIF5AL1 EIF5A

1.59e-052139231130465
Pubmed

Gc-globulin concentrations and C5 haplotype-tagging polymorphisms contribute to variations in serum activity of complement factor C5.

GC C5

1.59e-052139217428459
Pubmed

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

EIF5AL1 EIF5A

1.59e-052139217707773
Pubmed

Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.

EIF5AL1 EIF5A

1.59e-052139212894223
Pubmed

Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle.

SMARCD1 SMARCD3

1.59e-052139229092888
Pubmed

Eukaryotic initiation factor 5A and Ca2+ /calmodulin-dependent protein kinase 1D modulate trophoblast cell function.

CAMK1D EIF5A

1.59e-052139229533498
Pubmed

Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.

EIF5AL1 EIF5A

1.59e-052139237743008
Pubmed

REGÎł Mitigates Radiation-Induced Enteritis by Preserving Mucin Secretion and Sustaining Microbiome Homeostasis.

PSME3 MUC2

1.59e-052139238423356
Pubmed

Independent roles of eIF5A and polyamines in cell proliferation.

EIF5AL1 EIF5A

1.59e-052139215377278
Pubmed

Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.

EIF5AL1 EIF5A

1.59e-05213922492279
Pubmed

The mouse Laf4 gene: exon/intron organization, cDNA sequence, alternative splicing, and expression during central nervous system development.

AFF2 AFF3

1.59e-052139212079280
Pubmed

Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.

EIF5AL1 EIF5A

1.59e-052139237653021
Pubmed

Identification of a new member of the human eIF-5A gene family.

EIF5AL1 EIF5A

1.59e-05213927622067
Pubmed

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.

EIF5AL1 EIF5A

1.59e-05213928253832
Pubmed

Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.

EIF5AL1 EIF5A

1.59e-05213923095320
Pubmed

Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).

EIF5AL1 EIF5A

1.59e-052139211742107
InteractionACTC1 interactions

TPR KLHL2 GC FBXO30 KPTN RIF1 ZZZ3 LMO7 TLN1 SYNE2 EIF5A SMARCD1 SMARCD2 SMARCD3 ZFR BOD1L1 PSME3

4.49e-0669413617int:ACTC1
InteractionRGPD4 interactions

RGPD4 RANBP2 RGPD1 RGPD3

1.32e-05221364int:RGPD4
InteractionRGPD1 interactions

RGPD4 RANBP2 RGPD1 AP2B1 RGPD3

1.95e-05491365int:RGPD1
InteractionNUP50 interactions

SETD1A RANBP2 AP2B1 ZSCAN18 SMARCD1 SMARCD2 SMARCD3 ZFR BOD1L1 PSME3 SPEN

2.05e-0534113611int:NUP50
InteractionRGPD2 interactions

RGPD4 RANBP2 RGPD1 RGPD3

3.09e-05271364int:RGPD2
GeneFamilyProtein tyrosine phosphatases type IVA

PTP4A2 PTP4A3

6.38e-053842899
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF2 AFF3

1.27e-0448421145
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 RGPD1 TRANK1 RGPD3

1.97e-04115845769
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF2 AFF3

7.52e-0498421280
GeneFamilyT-boxes

EOMES TBX5

3.11e-0318842766
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RALGAPA1 CYLD TPR FNBP1 RANBP2 XRN2 CYTH1 DOCK9 KMT2E ANKLE2 INO80D RGS2 TGFBR3 PTP4A2 RIF1 TRANK1 TLN1 MACF1 PDS5A PCNX1 ZFR BOD1L1 SPEN FYB1 TASOR MYBL1

7.33e-08149213926M40023
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RANBP2 COL11A1 RGPD1 RGPD3

8.22e-07331395MM477
CoexpressionGSE36826_WT_VS_IL1R_KO_SKIN_DN

ACVR2A PPP1R14B SLC16A6 MTF1 PITPNA PSME3 SPEN ZNF614 HNRNPR

1.17e-061981399M9530
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

RANBP2 CYTH1 DOCK9 LARP4 ANKLE2 TGFBR3 RIF1 FAT1 ZZZ3 SYNE2 MACF1 PDS5A RPGR PARD3 SPEN TASOR MYBL1

3.08e-0685613917M4500
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RANBP2 RGPD1 SLC16A6 RGPD3

3.19e-06431395MM3857
CoexpressionGSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN

FNBP1 TBC1D15 WDFY4 TLR8 KCNRG TGFBR3 SH3PXD2A IL17RB

4.50e-061751398M7101
CoexpressionTABULA_MURIS_SENIS_AORTA_FIBROBLAST_OF_CARDIAC_TISSUE_AGEING

RALGAPA1 PIK3AP1 FNBP1 VWA8 CP KMT2E ANKLE2 PPP1R14B RGS2 EIF5AL1 PTP4A3 TLN1 LPL EIF5A VPS28

7.27e-0672313915MM3672
CoexpressionPGF_UP.V1_UP

LARP4 RGS2 TGFBR3 RIF1 ZZZ3 SYNE2 RPGR TASOR

8.24e-061901398M2674
CoexpressionGSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP

ACVR2A PTP4A2 SLC16A6 MTF1 PITPNA PSME3 SPEN HNRNPR

1.11e-051981398M9534
CoexpressionGSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP

KLHL2 CAMK1D CYTH1 RTN3 TLR8 TRANK1 SYNE2 BOD1L1

1.11e-051981398M7948
CoexpressionGSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_DN

RALGAPA1 TBC1D15 CP RGS2 CRHR2 KPTN ZNF614 TOP3A

1.20e-052001398M5364
CoexpressionNAKAMURA_ADIPOGENESIS_LATE_UP

TPR COL11A1 ACVR2A TGFBR3 IRF9 SMARCD2

1.41e-05981396M2026
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

RALGAPA1 CAMK1D RIF1 TLN1 SMARCD1 MACF1 IL17RB

5.10e-051801397M8239
CoexpressionGSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP

PIK3AP1 FNBP1 ACVR2A TLR8 AP1B1 MTF1 HNRNPR

8.72e-051961397M5862
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN

ACVR2A KMT2E INO80D NELL2 ZFR RPGR CLNK

9.00e-051971397M7921
CoexpressionGSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN

FNBP1 CAMK1D BCORL1 RGS2 SYNE2 CCDC25 CLNK

9.59e-051991397M7498
CoexpressionGSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN

RALGAPA1 PIK3AP1 ARPC1A ANKLE2 TLR8 ZFR VPS28

9.59e-051991397M8721
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP

DOCK9 TGFBR3 NELL2 SYNE2 ZSCAN18 MACF1 MYBL1

9.59e-051991397M4494
CoexpressionGSE10325_CD4_TCELL_VS_MYELOID_UP

CYLD TPR DOCK9 TGFBR3 NELL2 SYNE2 MYBL1

9.59e-051991397M3078
CoexpressionGSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN

PIK3AP1 EOMES TGFBR3 PTP4A2 SYNE2 PITPNA MYBL1

9.89e-052001397M4659
CoexpressionGSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP

RALGAPA1 KLHL2 VWA8 CYTH1 NELL2 SMARCD3 CCDC25

9.89e-052001397M8042
CoexpressionGSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP

CYLD SPATA7 CAMK1D PDS5A CCDC25 ZFR FYB1

9.89e-052001397M7500
CoexpressionGSE23695_CD57_POS_VS_NEG_NK_CELL_DN

CAMK1D ACVR2A LARP4 WDFY4 SLC16A6 TRAPPC9 TOP3A

9.89e-052001397M7786
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_500

LARP4 RGS2 FBXO30 RIF1 SYNE2 RPGR

2.64e-05911366gudmap_developingGonad_e12.5_ovary_k5_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200

TRANK1 MYBL1

4.07e-0521362gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_200
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

SETD1A KLHL2 MGAM TBC1D15 COL11A1 KMT2E LARP4 RGS2 FBXO30 RIF1 SYNE2 NAV2 PSME3 RPGR MYBL1 HNRNPR

5.80e-0580413616gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500

SETD1A KLHL2 MGAM KMT2E FBXO30 RIF1 SYNE2 PSME3 RPGR MYBL1 HNRNPR

7.95e-0541713611gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

SETD1A TBC1D15 TPRA1 DOCK9 LARP4 RGS2 RIF1 LMO7 SYNE2 NAV2 RPGR PARD3 IL17RB MYBL1 HNRNPR

1.27e-0477013615gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000

TBC1D15 LARP4 RGS2 FBXO30 RIF1 SYNE2 RPGR MYBL1

1.31e-042331368gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

CYLD SETD1A TBC1D15 MYO9A KMT2E LARP4 RGS2 FBXO30 RIF1 ALMS1 SYNE2 NAV2 RPGR MYBL1 HNRNPR

1.38e-0477613615gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

SETD1A KLHL2 MGAM COL11A1 AFF3 BCORL1 KMT2E RIF1 TLN1 SYNE2 NAV2 ZFR GAREM1 MYBL1 HNRNPR

1.68e-0479013615gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500

SETD1A TBC1D15 RIF1 LMO7 SYNE2 RPGR PARD3 IL17RB MYBL1 HNRNPR

1.69e-0437913610gudmap_developingGonad_P2_ovary_500
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Lv, CD45+ CD11c+ MHC-II+ CD11b low CD103+, Liver, avg-2

MYO9A WDFY4 RGS2 CLNK RASSF4

1.74e-04811365GSM538234_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RANBP2 CLCC1 RIF1 ALMS1 SYNE2 PDS5A BOD1L1 RPGR MYBL1

1.82e-043111369Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

SPATA7 RANBP2 RTN3 ACVR2A EPB41L4A LARP4 CLCC1 RIF1 NELL2 ALMS1 SYNE2 NAV2 PDS5A CCDC25 BOD1L1 RPGR MYBL1

1.99e-0498913617Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#4_top-relative-expression-ranked_1000

CYLD CP KCNRG TGFBR3 LMO7 SH3PXD2A

2.46e-041361366gudmap_kidney_adult_RenalCapsule_k4_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000

TBC1D15 LARP4 RGS2 RIF1 SYNE2 MYBL1

2.66e-041381366gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500

SETD1A MGAM COL11A1 AFF3 BCORL1 CP KMT2E SYNE2 MYBL1 HNRNPR

2.82e-0440413610gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

RALGAPA1 RANBP2 MYO9A RTN3 ACVR2A EPB41L4A INO80D CLCC1 RIF1 ALMS1 CGRRF1 SYNE2 PDS5A BOD1L1 MYBL1

2.88e-0483113615Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

SETD1A MGAM LARP4 RGS2 FBXO30 RIF1 SYNE2 NAV2 RPGR HNRNPR

3.10e-0440913610gudmap_developingGonad_e12.5_ovary_500
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR KIF13B RANBP2 AFF2 MYO9A TLR8 MACF1 ZFR TASOR

4.63e-091761399749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

PIK3AP1 EPB41L4A RGS2 TGFBR3 PTP4A2 TLN1 SYNE2 MACF1 MYBL1

6.51e-091831399f593a89b0aa8fffdfa403769916facfd30358521
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES TGFBR3 TRANK1 SYNE2 MACF1 PCNX1 FYB1 MYBL1

8.89e-081771398d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES TGFBR3 TRANK1 SYNE2 MACF1 PCNX1 FYB1 MYBL1

8.89e-081771398f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

EOMES TGFBR3 TRANK1 SYNE2 MACF1 PCNX1 FYB1 MYBL1

8.89e-0817713986978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EOMES TGFBR3 TRANK1 SYNE2 MACF1 PCNX1 FYB1 MYBL1

8.89e-081771398936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EOMES TGFBR3 TRANK1 SYNE2 MACF1 PCNX1 FYB1 MYBL1

8.89e-081771398d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR LARP4 PTP4A2 SYNE2 PITPNA PDS5A ZFR TASOR

1.60e-07191139860c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR LARP4 PTP4A2 SYNE2 PITPNA PDS5A ZFR TASOR

1.60e-07191139809db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR LARP4 PTP4A2 SYNE2 PITPNA PDS5A ZFR TASOR

1.60e-071911398973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CYLD KMT2E EOMES TGFBR3 TRANK1 SYNE2 MACF1 MYBL1

2.02e-071971398c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RALGAPA1 RANBP2 DOCK9 NELL2 SYNE2 MACF1 PCNX1

6.12e-0715613971545169694f686d28648a68b552c2ae606599d66
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

RALGAPA1 RANBP2 ACVR2A NELL2 SYNE2 MACF1 PCNX1

7.89e-071621397b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYLD CYTH1 DOCK9 IGSF22 SYNE2 PCNX1 MYBL1

9.68e-07167139783969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 CYLD RANBP2 ANKRD1 SYNE2 MACF1 PCNX1

1.13e-0617113972e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK GAREM1

1.85e-061841397ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK GAREM1

1.92e-061851397fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK GAREM1

1.92e-061851397929b68b05b7686341329ac756d7df172cb4b810b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RALGAPA1 RANBP2 INO80D SYNE2 MACF1 PCNX1 SPEN

2.13e-061881397ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK GAREM1

2.13e-0618813974bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

RASGRF1 DOCK9 AFF3 PTP4A3 SMARCD3 C5 GAREM1

2.13e-061881397ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 RANBP2 DOCK9 NELL2 SYNE2 MACF1 PCNX1

2.45e-06192139747646d7e4990be85072987f92bf18d52f8da752e
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

HS3ST5 CP EPB41L4A FAT1 LMO7 NAV2 GAREM1

2.54e-0619313972bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 CYTH1 AFF3 CAMK1G RGS2 PTP4A3 NAV2

2.62e-06194139711709704079f24a730476572dc2f01e9d2226e2c
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 CYTH1 AFF3 CAMK1G RGS2 PTP4A3 NAV2

2.62e-0619413973a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

PPP1R14C DOCK9 AFF3 LMO7 SYNE2 NAV2 PARD3

2.72e-061951397618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

PPP1R14C DOCK9 AFF3 LMO7 SYNE2 NAV2 PARD3

2.72e-06195139706ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

CYLD FNBP1 ANKLE2 PTP4A2 TLN1 BOD1L1 MYBL1

2.81e-0619613977bced0cc2112697593c478fa291b8ed3941fb811
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KMT2E EOMES TGFBR3 TRANK1 SYNE2 MACF1 MYBL1

2.90e-061971397836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

RASGRF1 CP NELL2 FAT1 PTP4A3 NAV2 C5

2.90e-0619713975e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

CYLD CYTH1 DOCK9 TRANK1 SH3PXD2A SYNE2 MACF1

3.00e-061981397ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellControl-NK|Control / Disease condition and Cell class

PIK3AP1 TGFBR3 TLN1 SYNE2 MACF1 RASSF4 MYBL1

3.10e-061991397f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TPR CYTH1 KMT2E IRF9 SYNE2 MACF1 BOD1L1

3.21e-06200139712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellVE|World / Condition, Cell_class and T cell subcluster

PPP1R14B PTP4A2 TRANK1 SYNE2 EIF5A MACF1 BOD1L1

3.21e-0620013978ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

IFT140 WDFY4 MTF1 ZSCAN18 SPEN GAREM1

1.20e-051621396810881210e015c788814e4fe8d7a24c929cf2621
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 FNBP1 CAMK1D TLR8 RASSF4 FYB1

1.43e-051671396991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 FNBP1 CAMK1D TLR8 RASSF4 FYB1

1.43e-051671396f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 FNBP1 CAMK1D TLR8 RASSF4 FYB1

1.43e-051671396934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A RGS2 TLR8 LPL RASSF4 FYB1

1.53e-051691396aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CYLD FNBP1 EIF5AL1 SYNE2 MACF1 FYB1

1.63e-05171139661318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellfacs-GAT-Fat-3m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CAMK1D WDFY4 TLR8 RASSF4 FYB1

1.63e-0517113963f796d53d3110e5d6e97de53bb49d323944659d6
ToppCellfacs-GAT-Fat-3m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CAMK1D WDFY4 TLR8 RASSF4 FYB1

1.63e-051711396d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCellfacs-GAT-Fat-3m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CAMK1D WDFY4 TLR8 RASSF4 FYB1

1.63e-051711396e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CAMK1D WDFY4 RGS2 CLNK RASSF4

1.69e-051721396e680abead2da75e50774da02384eb2729c839c01
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A GC KCNRG LPL MACF1 TASOR

1.74e-051731396869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A GC KCNRG LPL MACF1 TASOR

1.74e-0517313960672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A GC KCNRG LPL MACF1 TASOR

1.74e-051731396870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CAMK1D WDFY4 RGS2 CLNK RASSF4

1.86e-05175139616cf0c5d3d009480e07e8fe78c0f8555c2d6e3df
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A GC KCNRG LPL MACF1 TASOR

1.86e-0517513961ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK1D RGS2 LPL PITPNA RASSF4 FYB1

1.92e-051761396eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A EPB41L4A ANKRD1 LPL RASSF4 SPEN

1.92e-0517613965e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 FNBP1 AFF2 RASGRF1 AFF3 WDFY4

1.98e-0517713960d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A EPB41L4A ANKRD1 LPL RASSF4 SPEN

1.98e-05177139614fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR KIF13B RANBP2 LMO7 SYNE2 TASOR

2.05e-05178139601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 FNBP1 AFF2 AFF3 WDFY4 MYBL1

2.05e-051781396da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 FNBP1 AFF2 AFF3 WDFY4 MYBL1

2.05e-051781396580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 SYNE2 C5 CLNK

2.11e-051791396fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.18e-051801396b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RALGAPA1 CYLD EOMES TGFBR3 NELL2 MACF1

2.18e-051801396ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 C5 CLNK GAREM1

2.25e-0518113960513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CAMK1D CP LMO7 NAV2 PARD3 GAREM1

2.25e-051811396c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DOCK9 TRANK1 ZZZ3 SYNE2 PCNX1 FYB1

2.32e-0518213961aea96ee211f7b9caef7fd385233f51be6021a73
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR EOMES MACF1 PDS5A BOD1L1 TASOR

2.32e-051821396e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR EOMES MACF1 PDS5A BOD1L1 TASOR

2.32e-0518213961710eab3037a87609d21838be2d2d29c3bc36651
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK9 TRANK1 ZZZ3 SYNE2 PCNX1 FYB1

2.32e-051821396b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK9 TRANK1 ZZZ3 SYNE2 PCNX1 FYB1

2.32e-051821396c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.32e-05182139617ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK9 TRANK1 ZZZ3 SYNE2 PCNX1 FYB1

2.32e-0518213964cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

PIK3AP1 EOMES TRANK1 MACF1 PCNX1 FYB1

2.39e-05183139622bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EPB41L4A WDFY4 RGS2 PTP4A2 TLN1 MACF1

2.39e-051831396278064c9f0582463b83bf156d34e77f60187613b
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 C5 CLNK GAREM1

2.39e-051831396e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP NELL2 LMO7 NAV2 C5

2.47e-05184139651e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR XRN2 TLN1 MACF1 PDS5A TASOR

2.47e-0518413961154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Lung-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNBP1 CAMK1D WDFY4 RGS2 RASSF4 FYB1

2.47e-051841396c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.47e-051841396d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

PIK3AP1 TGFBR3 SYNE2 MACF1 PCNX1 MYBL1

2.47e-051841396791f1bcb954aadc63d4117c400537d036f68734d
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP NELL2 LMO7 NAV2 C5

2.54e-0518513960d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RALGAPA1 CYLD FNBP1 AFF3 KMT2E BOD1L1

2.54e-051851396e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

DOCK9 HS3ST5 CP LMO7 NAV2 PARD3

2.54e-051851396cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

MGAM TGFBR3 IRF9 TRANK1 SYNE2 MYBL1

2.62e-051861396ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 EOMES TGFBR3 SYNE2 FYB1 MYBL1

2.62e-05186139671e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 C5 CLNK GAREM1

2.62e-051861396e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL2 PPP1R14C DOCK9 PTP4A3 NAV2 GAREM1

2.62e-051861396acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.62e-051861396e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.70e-051871396201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

FNBP1 NELL2 SYNE2 PCNX1 FYB1 MYBL1

2.70e-051871396f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A CP LMO7 SYNE2 NAV2 C5

2.70e-05187139658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PIK3AP1 KIF13B ACVR2A LPL RPGR PRXL2C

2.70e-051871396c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCellLPS-IL1RA-Epithelial_alveolar|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R14C CP LMO7 NAV2 C5 CLNK

2.78e-0518813966164d467b612767ceba15de34176bcc8e8c36ab8
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FNBP1 WDFY4 PTP4A2 PTP4A3 TRANK1 TLN1

2.87e-05189139611cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK9 TGFBR3 NELL2 SYNE2 FYB1 MYBL1

2.87e-0518913965a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

AFF2 FAT1 SYNE2 PARD3 RASSF4 IL17RB

2.87e-0518913960be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

FNBP1 NELL2 SYNE2 PCNX1 FYB1 MYBL1

2.95e-0519013960733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KMT2E PTP4A2 FBN1 SH3PXD2A TLN1 MACF1

2.95e-051901396d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM AFF2 RTN3 HS3ST5 FBN1 NAV2

3.04e-0519113966c1283d51a845cff67ed5e500f7e944165297b53
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

HS3ST5 CP EPB41L4A FAT1 LMO7 GAREM1

3.04e-05191139623776c7302cead3881b39127398f3b3e0d27885e
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

FNBP1 DOCK9 NELL2 SYNE2 FYB1 MYBL1

3.04e-0519113960646cca78e24aeb6baa9934d3c439b797c567997
ToppCellCOPD-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

RALGAPA1 FNBP1 EOMES TGFBR3 SYNE2 MYBL1

3.13e-0519213965bfd9f5d47511441eb2d3cc3c4d7ed330ffd0bd1
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 MACF1 PCNX1 CLNK TRAPPC9 MYBL1

3.13e-051921396930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MGAM AFF2 RTN3 HS3ST5 FBN1 NAV2

3.13e-05192139686d561c30554ff04c21801d4aaf8e3c9efe49af4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

RANBP2 RIF1 SYNE2 MACF1 SPEN

4.92e-0550875GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

COL11A1 RIF1 FAT1 MACF1 SPEN

4.92e-0550875GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA

FNBP1 KLHL2 VWA8 DOCK9 KPTN AP2B1 TELO2 SMARCD1 KHK

3.32e-0619713891071_UP
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; HL60; HT_HG-U133A

CYTH1 DOCK9 INO80D CRHR2 MTF1 MUC2 TRAPPC9 GAREM1 MYBL1

3.32e-0619713893006_DN
DrugSaquinavir mesylate [149845-06-7]; Down 200; 5.2uM; PC3; HT_HG-U133A

TPR VWA8 EIF5A2 INO80D KPTN SMARCD3 PCNX1 C5 TOP3A

3.32e-0619713895770_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; HL60; HG-U133A

TPRA1 BCORL1 ANKLE2 PTP4A3 ALMS1 PCNX1 RASSF4 TRAPPC9 HNRNPR

3.46e-0619813891407_DN
DrugIndoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A

SETD1A CAMK1D CYTH1 INO80D IRF9 SMARCD1 PCNX1 CCDC25 IL17RB

3.60e-0619913893345_DN
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A

INO80D CRHR2 RIF1 PTP4A3 TRANK1 SMARCD1 MUC2 TOP3A

2.30e-0519213884268_UP
DrugBaclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A

CYLD TPR RGS2 ZBTB14 PTP4A3 TLN1 ZFR RPGR

2.67e-0519613881536_UP
DrugPheniramine maleate [132-20-7]; Down 200; 11.2uM; HL60; HG-U133A

SIN3B RANBP2 MYO9A INO80D KPTN MACF1 CCDC25 RASSF4

2.77e-0519713881992_DN
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A

CYLD INO80D ZBTB14 AP2B1 PDS5A PCNX1 ZFR GAREM1

2.77e-0519713882103_UP
DrugClofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A

RALGAPA1 SETD1A CYTH1 DOCK9 TLR8 TGFBR3 FBN1 SMARCD1

2.77e-0519713883187_UP
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A

SETD1A IFT140 AFF2 RASGRF1 TLR8 SH3PXD2A RASSF4 FYB1

2.87e-0519813884265_UP
DrugParomomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A

RALGAPA1 PTP4A3 SMARCD1 CCDC25 KHK RPGR TOP3A FOXI1

2.87e-0519813883356_DN
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A

TPR SETD1A DOCK9 BCORL1 CINP PTP4A3 ZSCAN18 KHK

2.87e-0519813882057_UP
DrugConessine [546-06-5]; Down 200; 11.2uM; HL60; HT_HG-U133A

VWA8 TLR8 SH3PXD2A PCNX1 CCDC25 TRAPPC9 TOP3A MYBL1

2.98e-0519913882135_DN
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; HL60; HT_HG-U133A

AP2B1 PITPNA PDS5A PCNX1 ZFR C5 PARD3 TOP3A

2.98e-0519913881265_DN
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCD1 SMARCD2 SMARCD3

7.04e-0691313DOID:1925 (implicated_via_orthology)
DiseaseHeadache, HOMA-IR

CAMK1D NAV2

1.17e-0441312EFO_0004501, HP_0002315
DiseaseIntellectual Disability

RALGAPA1 SETD1A AFF3 KMT2E AP1B1 MTF1 SMARCD1 MACF1 HNRNPR

1.80e-044471319C3714756
Diseaserheumatoid arthritis

TPRA1 AFF3 WDFY4 EOMES TELO2 MTF1 SH3PXD2A C5 CLNK

2.29e-044621319EFO_0000685
Diseaseneuroimaging measurement

SPATA7 KIF6 COL11A1 DOCK9 AFF3 RGPD1 LARP4 PGM1 FZD9 NELL2 SH3PXD2A NAV2 MACF1 PARD3

2.95e-04106913114EFO_0004346
DiseaseMalignant neoplasm of breast

KIF6 COL11A1 BCORL1 RGS2 EOMES RIF1 UNC45B SYNE2 ANKRD30A SMARCD1 MACF1 BOD1L1 SPEN HNRNPR

3.09e-04107413114C0006142
DiseasePR interval

KIF13B EOMES FAT1 SH3PXD2A SYNE2 NAV2 MACF1 GAREM1 TBX5

3.80e-044951319EFO_0004462
Diseaseliver cirrhosis (biomarker_via_orthology)

RGS2 FBN1 MUC2

4.63e-04341313DOID:5082 (biomarker_via_orthology)
Diseasetriacylglycerol 52:4 measurement

ZBTB14 LPL TASOR

5.49e-04361313EFO_0010416
DiseaseParoxysmal atrial fibrillation

CYTH1 SH3PXD2A SYNE2 NAV2 TBX5

6.75e-041561315C0235480
Diseasefamilial atrial fibrillation

CYTH1 SH3PXD2A SYNE2 NAV2 TBX5

6.75e-041561315C3468561
DiseasePersistent atrial fibrillation

CYTH1 SH3PXD2A SYNE2 NAV2 TBX5

6.75e-041561315C2585653
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 40

KMT2E HNRNPR

6.90e-0491312C4225275
DiseaseAtrial Fibrillation

CYTH1 SH3PXD2A SYNE2 NAV2 TBX5

7.56e-041601315C0004238
DiseaseMarfan syndrome (implicated_via_orthology)

ACVR2A FBN1

8.60e-04101312DOID:14323 (implicated_via_orthology)
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

TPRA1 AFF3 WDFY4 EOMES CLNK

9.93e-041701315EFO_0000685, EFO_0007791, EFO_0007837
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

XRCC1 FAT1 SPEN

1.06e-03451313DOID:3748 (is_implicated_in)
DiseaseColorectal Carcinoma

AKAP3 XRCC1 CINP FBXO30 PGM1 FAT1 ZZZ3 ERGIC3 LMO7 WDR49

1.19e-0370213110C0009402
Diseaseblood copper measurement

CAMK1D KRT82 CP

1.44e-03501313EFO_0007578
Diseasecolitis (implicated_via_orthology)

CRHR2 MUC2

1.48e-03131312DOID:0060180 (implicated_via_orthology)
DiseaseAbnormality of chromosome segregation

ZBTB14 FZD9 FYB1

2.43e-03601313HP_0002916
Diseaseserum gamma-glutamyl transferase measurement

PIK3AP1 MYO9A CYTH1 EIF5A2 PGM1 FZD9 TRANK1 ZZZ3 TLN1 NAV2 PARD3

2.58e-0391413111EFO_0004532
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

WDFY4 C5 CLNK

2.80e-03631313EFO_0000685, EFO_0007791, EFO_0009459
DiseaseMyeloid Leukemia

KMT2E SMARCD2

2.86e-03181312C0023470
DiseaseLeukemia, Monocytic, Chronic

KMT2E SMARCD2

2.86e-03181312C0023466
DiseaseHeadache

CAMK1D TGFBR3 MACF1

2.92e-03641313HP_0002315
DiseaseSeizures

AFF3 KMT2E KPTN MACF1 HNRNPR

2.95e-032181315C0036572
DiseaseGlobal developmental delay

KMT2E AP1B1 SMARCD1 HNRNPR

2.97e-031331314C0557874
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

IRF9 SMARCD1

3.18e-03191312DOID:1168 (biomarker_via_orthology)
Diseaseemphysema pattern measurement

VWA8 TRAPPC9

3.18e-03191312EFO_0005850
Diseasebrain measurement, neuroimaging measurement

KIF6 COL11A1 RGPD1 PGM1 SH3PXD2A NAV2 MACF1 PARD3

3.24e-035501318EFO_0004346, EFO_0004464
DiseaseFEV/FEC ratio

MGAM TPRA1 CAMK1D DOCK9 AFF3 TGFBR3 NELL2 FBN1 SH3PXD2A SYNE2 NAV2 PARD3 TBX5

3.27e-03122813113EFO_0004713
DiseaseRetinal Degeneration

CP RPGR

3.89e-03211312C0035304
Diseasehemorrhoid

ACVR2A AP1B1 LMO7 TBX5

4.25e-031471314EFO_0009552
DiseaseLeber Congenital Amaurosis

SPATA7 IFT140

4.26e-03221312C0339527

Protein segments in the cluster

PeptideGeneStartEntry
RKCDNEDDYREIKKS

AFF3

821

P51826
PSIKCEDINAEEYSK

EOMES

656

O95936
SRNKYDKTPEDVICE

ANKLE2

441

Q86XL3
KDEDPYVRKTAAVCV

AP2B1

131

P63010
SDKNNPDVCDEYKRT

ANKRD1

141

Q15327
RRDCKADVDTKPAYQ

BOD1L2

56

Q8IYS8
CTATELYQAVEKAKP

AFF2

446

P51816
YDRTDCVEKKDSPEV

ACVR2A

86

P27037
KTCRIAAKPYEEQVN

BCORL1

906

Q5H9F3
SVDELKIPKDCDRYD

ALMS1

326

Q8TCU4
RADEILPSESKQKDY

ANKRD30A

666

Q9BXX3
KDEDPYVRKTAAVCV

AP1B1

131

Q10567
CDDEPETYVAAVKKA

PIK3AP1

126

Q6ZUJ8
CRVFSAYIKEVDEKP

ARPC1A

166

Q92747
ATPSFEDLVEKYCEK

POLN

361

Q7Z5Q5
SKTIEEYAVCPDLKV

PGM1

151

P36871
PEEQEECKNYLRKTR

RANBP2

701

P49792
PDESKTNEKLYTVCD

PDS5A

1066

Q29RF7
ESGERTKLKDCEYPL

RASSF4

226

Q9H2L5
RSQVLSKDYKAEEDP

PITPNA

146

Q00169
IKTYCSEPEKVDKDN

CP

236

P00450
DYDTKVVDLDPCLSK

FAT1

4331

Q14517
IDCNKIYERVVEKPS

NELL2

166

Q99435
IDIFTGKKYEDICPS

EIF5A2

61

Q9GZV4
SIKIRDEEKIDCYPD

MGAM

1851

O43451
IDTKDDYNALSVCPK

IL17RB

451

Q9NRM6
ETCIYPDKKSEGVRI

COL11A1

1646

P12107
DPNTCEVNTKYKAVR

HS3ST5

216

Q8IZT8
EYCSSRRAKPVDVDK

PCNX1

1771

Q96RV3
AKETKDRPLQDEYSV

KPTN

261

Q9Y664
NEENPSKAYRCSSKE

LPL

281

P06858
RPIYEEDLKKCVTAD

MUC2

1171

Q02817
DAYPKTLEDFRVKTC

ERGIC3

11

Q9Y282
YPCNRVKTDSVDLKS

GAREM1

596

Q9H706
TDDTKVLCRNEEGKY

FYB1

741

O15117
EAVKLCDSYEIRPGK

HNRNPR

221

O43390
SKINYSQCEPILDDK

CRHR2

91

Q13324
SQCEPILDDKQRKYD

CRHR2

96

Q13324
SIREVEDSKKPNCFE

CYTH1

311

Q15438
DCQEPLKEEEYRKLR

KIF6

451

Q6ZMV9
IKSDDETCRNGYKPI

KMT2E

916

Q8IZD2
NKDAYRPTTDADKIE

MACF1

3236

O94854
CYLEEEKAKTRSIPN

LMO7

381

Q8WWI1
IDIFTGKKYEDICPS

EIF5A

61

P63241
KTECYSFERIKSPEV

KCNRG

236

Q8N5I3
KKYEEELSLRPCVEN

KRT82

206

Q9NSB4
TKVERFPDLAAEKEC

CCDC25

136

Q86WR0
YPDREDCTTEKGKKT

MACF1

2056

Q9UPN3
HLLEKDPNERYTCEK

CAMK1G

256

Q96NX5
IYRIDEKSLDESKNP

OTOP1

371

Q7RTM1
SPEEQEECKNYLRKT

RGPD3

701

A6NKT7
APKCEQDLTIKNDYS

BOD1L1

2596

Q8NFC6
EPESSSYQENCRKRK

FRG2C

86

A6NGY1
CENPEKFQYVEKSRS

FZD9

196

O00144
KLEPLTSDDSDNYKC

IGSF22

126

Q8N9C0
IDIFTGKKYEDICPS

EIF5AL1

61

Q6IS14
PKSYCLENEEAVRKI

KLHL11

566

Q9NVR0
KDSDEEDSQPLKCIY

DOCK9

671

Q9BZ29
VPTSYVEVCLDKNAK

FNBP1

601

Q96RU3
FIYKPDLKTCEDIDE

FBN1

796

P35555
ETRKQTACKPEIAYA

C5

1546

P01031
VYKEKDNEELTISCP

LARP4

511

Q71RC2
LEDKTAPFKQCEYVA

INO80D

41

Q53TQ3
CALNKSSEFKEVPER

IRF9

86

Q00978
DKYPKEDSEIRCLSQ

KHK

21

P50053
SLNDCFKKVPRDEDD

FOXI1

176

Q12951
ECYDDPDISAGKIKQ

CYLD

801

Q9NQC7
KCSYNVVEKREEAIP

FBXO30

706

Q8TB52
CKAYSPEDLEERKNS

GEMIN6

91

Q8WXD5
SKEEIYCQLPRDTKI

CGRRF1

146

Q99675
EDPCKLKEEITRYQF

EPB41L4A

101

Q9HCS5
RRTYTEDPKESIKQC

IFT140

1346

Q96RY7
LKEEDEPAYKSCKQE

MYBL1

601

P10243
RAAIDKSYDKPAVDD

PARD3

926

Q8TEW0
FPEEQEECKNYLRKT

RGPD1

691

P0DJD0
EALVDCYKPTEEFIK

PPP1R14C

131

Q8TAE6
LKLCSKANVYTEVPD

SLC16A6

6

O15403
YDFKCDRLSEIPEEK

RPGR

781

Q92834
KECEEDNPVIRSYFK

KIF13B

771

Q9NQT8
EIPSCEREEKTSKNF

RTN3

541

O95197
SPEEQEECKNYLRKT

RGPD4

701

Q7Z3J3
ESEFYQDLCKKPQIT

RGS2

191

P41220
DKTEKPCLLSEYTEN

SAXO1

26

Q8IYX7
PNDQKKTACYDIDVE

SMARCD1

381

Q96GM5
CLTPELSELKKQYES

SYNE2

1806

Q8WXH0
RKEEECSTTDHPYKK

TBX5

326

Q99593
LPNVCEEKNETSKYA

RIF1

1646

Q5UIP0
QSECPETKRKEVKRY

MTF1

126

Q14872
VYSTPEEKCQSEIRK

NAV2

1681

Q8IVL1
SVDPSDQKKTACYDI

SMARCD3

346

Q6STE5
KKTPYEEQLHRCEDE

SIN3B

476

O75182
LKSSKAPAYVRDCVE

TELO2

506

Q9Y4R8
KHYEAKPDCEERTLE

RASGRF1

361

Q13972
EKDKYLDVCPVSARQ

SETD1A

1506

O15047
EKDPNKRYTCEQAAR

CAMK1D

261

Q8IU85
ARVKELLVDCYKPTE

PPP1R14B

111

Q96C90
DPNDQKKTACYDIDV

SMARCD2

396

Q92925
KKTACYDIDVEVDDP

SMARCD2

401

Q92925
DKKDYEQPTCAKVEN

TASOR

821

Q9UK61
REKMYSEPKSEEETC

AKAP3

431

O75969
DCSTKSKEEPYVLAV

CLNK

336

Q7Z7G1
PASKENEEKVCLEYN

CINP

71

Q9BW66
CEKKKREDYESQSNP

CLCC1

81

Q96S66
FDELKTDYKNPIDQC

CNIH1

31

O95406
GPTYKKRRLDECEEA

PSME3

81

P61289
CKEYVEDLAKIPRSF

PRXL2C

71

Q7RTV5
RKICEEYITGKFDPQ

UNC45B

376

Q8IWX7
AEENFSRSYPCDEKK

TLR8

26

Q9NR97
SRSYPCDEKKQNDSV

TLR8

31

Q9NR97
SEPKILFSYKCQVDE

TPRA1

286

Q86W33
DKLCSQKRDVSSPDE

ZBTB14

121

O43829
VRVCEVTYDKTPLEK

PTP4A3

46

O75365
ETNEAIYCTKEPFIK

RALGAPA1

286

Q6GYQ0
KNYCSLRDETPERKS

SPEN

1131

Q96T58
QKDPDTEEYRKLLSE

TPR

1346

P12270
IDTPKCNLLYSKDTE

PRSS27

186

Q9BQR3
PSDAYTKKELIECAR

TLN1

1941

Q9Y490
RPVEDKKRYENTDSD

TMEM232

241

C9JQI7
CDATYDKAPVEKEGI

PTP4A2

46

Q12974
ASESQDSPRKLKYEE

SH3PXD2A

541

Q5TCZ1
PSEDINLDIKYKERS

WDR49

576

Q8IV35
SRKYPSIIVNCVEEK

XRN2

11

Q9H0D6
QKINAREKPYECEEC

ZNF607

161

Q96SK3
RQAKDPECKTEDFVS

WDFY4

2211

Q6ZS81
ALEKAYIKDCVSPSE

VPS28

51

Q9UK41
NDEICEAFRKDPKEY

GC

141

P02774
SNCVTYDAKEKIAPL

SPATA7

306

Q9P0W8
VYVKVKSAEPADCAE

SNHG28

86

P0DPA3
SLEKYVVLCESPQDK

TBC1D15

176

Q8TC07
YCPENFVDIKKTLER

TOP3A

121

Q13472
SPEKYDIKCAVSEAA

ZFR

836

Q96KR1
AQYPESCKKAASLVE

ZSCAN18

111

Q8TBC5
DRVKIVCSQPYSKDS

XRCC1

126

P18887
NCLSPEDIIDKYKEA

TRAPPC9

316

Q96Q05
HQRIRTEEKPYKCEE

ZNF355P

381

Q9NSJ1
KTNTTDKICIPNEYR

ZNF614

251

Q8N883
KRIPRCYVEDTEAEK

TRANK1

946

O15050
TDDNLEPELKDYKCE

VWA8

711

A3KMH1
EPELKDYKCEVTSGT

VWA8

716

A3KMH1
SKPRENKDVLAFTCE

PSG5

156

Q15238
RKEDSYIDHKVPCTD

ZZZ3

256

Q8IYH5
IENICPKDESVKFYS

TGFBR3

656

Q03167
APKAIRSVECYDFKE

KLHL2

316

O95198
KKTYRDDSIDICNPE

MYO9A

436

B2RTY4