Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

3.39e-06102806GO:0005249
GeneOntologyMolecularFunctionpotassium channel activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

1.26e-05128806GO:0005267
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

3.33e-05152806GO:0022843
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

5.64e-05167806GO:0015079
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

9.07e-05182806GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

9.63e-05184806GO:0022832
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA2 KCNA3 KCNA4

1.89e-0428803GO:0005251
GeneOntologyMolecularFunctionU2 snRNA binding

ISG20 PRPF8

2.35e-046802GO:0030620
GeneOntologyMolecularFunctionpolysaccharide binding

CLEC18A CLEC18B CLEC18C

2.57e-0431803GO:0030247
GeneOntologyMolecularFunctiongated channel activity

KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 KCNN2 KCNH3

3.84e-04334807GO:0022836
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC1

4.37e-048802GO:0015431
GeneOntologyMolecularFunctionU1 snRNA binding

ISG20 PRPF8

4.37e-048802GO:0030619
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 KCNN2 KCNH3

4.50e-04343807GO:0005261
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC3 ABCC1

5.60e-049802GO:0034040
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC1

6.99e-0410802GO:0043225
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCC1 ABCD3

9.99e-0449803GO:0140359
GeneOntologyMolecularFunctionlipid transporter activity

ABCC3 ABCC1 ABCD3 ATG2A APOE

1.15e-03196805GO:0005319
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC1

1.61e-0315802GO:0008559
GeneOntologyMolecularFunctiontransporter activity

ABCC3 ABCC1 KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 ABCD3 KCNN2 ATG2A APOE SLC4A3 KCNH3

1.75e-0312898013GO:0005215
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNA2 KCNA4

2.07e-0317802GO:0099508
GeneOntologyMolecularFunctionlong-chain fatty acid transmembrane transporter activity

ABCC1 ABCD3

2.33e-0318802GO:0005324
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 KCNN2 KCNH3

2.43e-03459807GO:0005216
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC3 ABCC1 ABCD3

3.15e-0373803GO:0170055
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ABCC3 ABCC1 KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 SLC4A3 KCNH3

3.26e-03758809GO:0015318
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

ABCC1 ABCD3

3.80e-0323802GO:0015245
GeneOntologyMolecularFunctionmitogen-activated protein kinase kinase kinase binding

SASH1 MAPK1

4.84e-0326802GO:0031435
GeneOntologyMolecularFunctionchannel activity

KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 KCNN2 KCNH3

5.07e-03525807GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNA2 KCNH8 KCNA3 KCNA4 PIEZO1 KCNN2 KCNH3

5.12e-03526807GO:0022803
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNA2 KCNA3

5.21e-0327802GO:0015271
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R42 TAS2R50

5.21e-0327802GO:0033038
GeneOntologyCellularComponentdendrite

WHRN KCNA2 KCNA4 UCN KIF1B BRINP2 CNTNAP4 KCNN2 TNK2 MAPK1 APOE

3.69e-048587911GO:0030425
GeneOntologyCellularComponentdendritic tree

WHRN KCNA2 KCNA4 UCN KIF1B BRINP2 CNTNAP4 KCNN2 TNK2 MAPK1 APOE

3.76e-048607911GO:0097447
GeneOntologyCellularComponentpostsynapse

WHRN KCNA2 KCNA3 KCNA4 GPR158 KIF1B RPS13 KCNN2 DAPK1 TNK2 LRRTM3 MAPK1

4.19e-0410187912GO:0098794
GeneOntologyCellularComponentpresynapse

WHRN KCNA2 KCNA3 EFNB1 KCNA4 GPR158 UCN KIF1B RAB40AL CNTNAP4 TNK2

4.83e-048867911GO:0098793
GeneOntologyCellularComponentpresynaptic membrane

KCNA2 KCNA3 EFNB1 KCNA4 GPR158 CNTNAP4

6.34e-04277796GO:0042734
MousePhenoabnormal single cell response

KCNA2 KCNH8 KCNN2 KCNH3

2.26e-0535674MP:0003463
DomainK_chnl_volt-dep_Kv1

KCNA2 KCNA3 KCNA4

4.33e-068813IPR003972
Domain-

CLEC18A CLEC18B CLEC18C

3.44e-05158133.40.33.10
DomainCAP

CLEC18A CLEC18B CLEC18C

3.44e-0515813PF00188
DomainCAP_domain

CLEC18A CLEC18B CLEC18C

3.44e-0515813IPR014044
DomainSCP

CLEC18A CLEC18B CLEC18C

3.44e-0515813SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18B CLEC18C

3.44e-0515813IPR001283
DomainK_chnl_volt-dep_ELK

KCNH8 KCNH3

5.56e-053812IPR003950
DomainMultidrug-R_assoc

ABCC3 ABCC1

1.11e-044812IPR005292
DomainIon_trans_dom

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

1.37e-04114815IPR005821
DomainIon_trans

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

1.37e-04114815PF00520
DomainK_chnl_volt-dep_Kv

KCNA2 KCNA3 KCNA4

2.13e-0427813IPR003968
DomainABC_TM1F

ABCC3 ABCC1 ABCD3

2.38e-0428813PS50929
DomainABC1_TM_dom

ABCC3 ABCC1 ABCD3

2.38e-0428813IPR011527
DomainVG_K_chnl

KCNA2 KCNA3 KCNA4

3.90e-0433813IPR028325
DomainABC_transporter_CS

ABCC3 ABCC1 ABCD3

7.99e-0442813IPR017871
DomainPAS_9

KCNH8 KCNH3

8.17e-0410812PF13426
DomainC-type_lectin_CS

CLEC18A CLEC18B CLEC18C

8.56e-0443813IPR018378
DomainABC_tran

ABCC3 ABCC1 ABCD3

1.18e-0348813PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCC1 ABCD3

1.18e-0348813PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCC1 ABCD3

1.25e-0349813PS00211
DomainABC_transporter-like

ABCC3 ABCC1 ABCD3

1.33e-0350813IPR003439
DomainBTB_2

KCNA2 KCNA3 KCNA4

1.57e-0353813PF02214
DomainT1-type_BTB

KCNA2 KCNA3 KCNA4

1.57e-0353813IPR003131
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH8 KCNH3

1.63e-0314812IPR003938
DomainChannel_four-helix_dom

KCNA2 KCNA3 KCNA4

1.94e-0357813IPR027359
Domain-

KCNA2 KCNA3 KCNA4

1.94e-03578131.20.120.350
DomainEGF

CLEC18A CLEC18B BRINP2 CNTNAP4 CLEC18C

3.56e-03235815SM00181
DomainCupredoxin

EFNB1 PRPF8

4.06e-0322812IPR008972
DomainPAS_fold_3

KCNH8 KCNH3

4.43e-0323812IPR013655
DomainPAS_3

KCNH8 KCNH3

4.43e-0323812PF08447
DomainPAS-assoc_C

KCNH8 KCNH3

4.82e-0324812IPR000700
DomainABC_membrane

ABCC3 ABCC1

4.82e-0324812PF00664
DomainEGF_1

CLEC18A CLEC18B CNTNAP4 CLEC18C MUC12

5.03e-03255815PS00022
DomainC_TYPE_LECTIN_1

CLEC18A CLEC18B CLEC18C

5.08e-0380813PS00615
DomainEGF-like_CS

CLEC18A CLEC18B CNTNAP4 CLEC18C MUC12

5.54e-03261815IPR013032
DomainTAS2R

TAS2R42 TAS2R50

5.64e-0326812PF05296
DomainPAC

KCNH8 KCNH3

5.64e-0326812IPR001610
DomainPAC

KCNH8 KCNH3

5.64e-0326812SM00086
DomainPAC

KCNH8 KCNH3

5.64e-0326812PS50113
DomainT2R

TAS2R42 TAS2R50

5.64e-0326812IPR007960
DomainLectin_C

CLEC18A CLEC18B CLEC18C

5.82e-0384813PF00059
DomainCLECT

CLEC18A CLEC18B CLEC18C

5.82e-0384813SM00034
DomainEGF_2

CLEC18A CLEC18B CNTNAP4 CLEC18C MUC12

5.91e-03265815PS01186
DomainC_TYPE_LECTIN_2

CLEC18A CLEC18B CLEC18C

6.01e-0385813PS50041
DomainC-type_lectin-like

CLEC18A CLEC18B CLEC18C

6.21e-0386813IPR001304
DomainSH3_2

SASH1 MCF2L MYO15A

6.21e-0386813IPR011511
PathwayBIOCARTA_BARR_MAPK_PATHWAY

KCNA2 KCNA3 KCNA4 MAPK1

3.07e-0714614MM1489
PathwayBIOCARTA_BARRESTIN_SRC_PATHWAY

KCNA2 KCNA3 KCNA4 MAPK1

7.24e-0717614MM1491
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

8.53e-0741615MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

1.09e-0643615M1056
PathwayREACTOME_POTASSIUM_CHANNELS

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

5.27e-06103616M1073
PathwayBIOCARTA_BARRESTIN_PATHWAY

KCNA2 KCNA3 KCNA4

1.24e-0511613MM1501
PathwayBIOCARTA_BARR_MAPK_PATHWAY

KCNA2 KCNA3 MAPK1

2.71e-0514613M668
PathwayBIOCARTA_BARRESTIN_SRC_PATHWAY

KCNA2 KCNA3 MAPK1

5.02e-0517613M111
PathwayREACTOME_NEURONAL_SYSTEM

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 LRRTM3 MAPK1 ADCY5 KCNH3

6.31e-05411619M735
PathwayREACTOME_POTASSIUM_CHANNELS

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

6.40e-0598615MM14545
PathwayREACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT

ABCD3 PEX11B ALDH3A2

7.11e-0519613MM15651
PathwayREACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT

ABCD3 PEX11B ALDH3A2

8.34e-0520613M27930
PathwayBIOCARTA_MRP_PATHWAY

ABCC3 ABCC1

1.83e-045612MM1586
PathwayBIOCARTA_MRP_PATHWAY

ABCC3 ABCC1

2.73e-046612M22078
PathwayREACTOME_SIGNALING_BY_GPCR

TAS2R42 OXTR FFAR1 UCN KEL MAPK1 MCF2L TAS2R50 ADCY5 GLP2R

4.14e-046466110MM14962
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

ABCC3 ABCC1

5.07e-048612M48022
PathwayREACTOME_NEURONAL_SYSTEM

KCNA2 KCNH8 KCNA3 KCNA4 LRRTM3 ADCY5 KCNH3

5.83e-04335617MM14503
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18B CLEC18C

1.22e-08381326170455
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18B CLEC18C

1.22e-08381316336259
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18B CLEC18C

1.22e-08381333603190
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

3.73e-084081516382104
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18A CLEC18B CLEC18C

4.86e-08481316709836
Pubmed

Subunit composition of Kv1 channels in human CNS.

KCNA2 KCNA3 KCNA4

1.21e-07581310428084
Pubmed

Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.

KCNA2 KCNA3 KCNA4

2.42e-0768138938729
Pubmed

Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.

KCNA2 KCNA3 KCNA4

2.42e-07681314686897
Pubmed

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

KCNA2 KCNA3 KCNA4

4.23e-0778137477295
Pubmed

N-terminal PDZ-binding domain in Kv1 potassium channels.

KCNA2 KCNA3 KCNA4

6.76e-07881312435606
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNA2 KCNH8 KCNA3 KCNA4 KCNN2 KCNH3

9.28e-0713981616985003
Pubmed

Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.

KCNA2 KCNA3 KCNA4

1.44e-06108131383027
Pubmed

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

KCNA2 KCNH8 KCNH3

1.44e-061081326503718
Pubmed

Mutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereocilium.

WHRN MYO15A

5.36e-06281215590699
Pubmed

Whirler mutant hair cells have less severe pathology than shaker 2 or double mutants.

WHRN MYO15A

5.36e-06281217619105
Pubmed

An epilepsy-associated KV1.2 charge-transfer-center mutation impairs KV1.2 and KV1.4 trafficking.

KCNA2 KCNA4

5.36e-06281235439054
Pubmed

Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons.

KCNH8 KCNH3

5.36e-06281237516908
Pubmed

Vasoprotective effects of urocortin 1 against atherosclerosis in vitro and in vivo.

UCN APOE

5.36e-06281225462164
Pubmed

Expression and chromosomal localization of a lymphocyte K+ channel gene.

KCNA2 KCNA3

5.36e-0628122251283
Pubmed

Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding.

ABCD3 APOE

5.36e-0628127772082
Pubmed

Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice.

GCLM APOE

5.36e-06281221868708
Pubmed

Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.

GCLM APOE

5.36e-06281235447412
Pubmed

Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.

DNHD1 JADE2 LUZP1

8.08e-061781312693554
Pubmed

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

ABCC3 ABCC1

1.60e-05381212628490
Pubmed

Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.

ABCC3 ABCC1

1.60e-05381218799096
Pubmed

Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function.

KCNA2 KCNA4

1.60e-05381210428758
Pubmed

Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.

KCNA3 KCNA4

1.60e-0538121986382
Pubmed

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

ABCC3 ABCC1

1.60e-05381215886284
Pubmed

Subunit composition determines Kv1 potassium channel surface expression.

KCNA2 KCNA4

1.60e-05381210896669
Pubmed

Human potassium channel genes: Molecular cloning and functional expression.

KCNA2 KCNA4

1.60e-05381219912772
Pubmed

Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

ABCC3 ABCC1

1.60e-05381217494643
Pubmed

[Expression of ATP-binding Cassette Proteins Pgp, MRP1, and MRP3 in Malignant and Benign Ovarian Lesions].

ABCC3 ABCC1

1.60e-05381227739315
Pubmed

Induction of multidrug resistance proteins MRP1 and MRP3 and gamma-glutamylcysteine synthetase gene expression by nonsteroidal anti-inflammatory drugs in human colon cancer cells.

ABCC3 ABCC1

1.60e-05381211820781
Pubmed

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.

WHRN MYO15A

1.60e-05381215654330
Pubmed

Vitamin K-dependent Gas6 activates ERK kinase and stimulates growth of cardiac fibroblasts.

AXL MAPK1

1.60e-05381215184064
Pubmed

Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

ABCC3 ABCC1

1.60e-05381217845218
Pubmed

Distribution and functional properties of human KCNH8 (Elk1) potassium channels.

KCNH8 KCNH3

1.60e-05381212890647
Pubmed

Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication.

ABCC1 APOE

1.60e-05381222426312
Pubmed

Multidrug resistance protein-1 affects oxidative stress, endothelial dysfunction, and atherogenesis via leukotriene C4 export.

ABCC1 APOE

1.60e-05381218506003
Pubmed

ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.

ABCC3 ABCC1

1.60e-05381221799180
Pubmed

Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex.

WHRN MYO15A

1.60e-05381233626355
Pubmed

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1.

PIEZO1 UCN

1.60e-05381228698554
Pubmed

A family of three mouse potassium channel genes with intronless coding regions.

KCNA2 KCNA3

1.60e-0538122305265
Pubmed

Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.

KCNA2 KCNA3 KCNA4

3.04e-05268137905852
Pubmed

Whirlin complexes with p55 at the stereocilia tip during hair cell development.

WHRN MYO15A

3.20e-05481216829577
Pubmed

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

WHRN MYO15A

3.20e-05481215590698
Pubmed

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8.

WHRN MYO15A

3.20e-05481221236676
Pubmed

HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the blood-brain barrier.

ABCC1 MAPK1

3.20e-05481216395283
Pubmed

Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis.

MAPK1 APOE

3.20e-05481223991041
Pubmed

KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.

KCNA2 KCNA3

3.20e-05481212944270
Pubmed

Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.

ABCC3 ABCC1

3.20e-05481216946557
Pubmed

Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism.

FFAR1 MAPK1

3.20e-05481222593579
Pubmed

Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.

ABCC3 ABCC1

3.20e-05481218038766
Pubmed

Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice.

MAPK1 APOE

3.20e-05481225810299
Pubmed

Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.

WHRN MYO15A

3.20e-05481228387217
Pubmed

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK.

DAPK1 MAPK1

3.20e-05481215616583
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

ABCC3 ABCC1 GCLM

4.72e-053081320200426
Pubmed

A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors.

KCNA2 KCNA4

5.33e-05581211149959
Pubmed

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.

WHRN MYO15A

5.33e-05581220332152
Pubmed

Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family.

FFAR1 MAPK1

5.33e-05581222712802
Pubmed

Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism.

AXL MAPK1

5.33e-05581228100259
Pubmed

K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

KCNA2 KCNA3

5.33e-0558122333511
Pubmed

Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.

KCNA2 KCNA3

5.33e-05581221233214
Pubmed

Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.

ABCC3 ABCC1

5.33e-05581222272278
Pubmed

Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia.

WHRN MYO15A

5.33e-05581218160714
Pubmed

Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.

DAPK1 APOE

7.99e-05681218813964
Pubmed

Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.

KCNA2 KCNA3

7.99e-0568129286706
Pubmed

Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.

MYO15A ALDH3A2

7.99e-0568129529344
Pubmed

Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.

MAPK1 ADCY5

7.99e-05681224944202
Pubmed

Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.

MAPK1 APOE

7.99e-05681218208815
Pubmed

Expressions of hepatobiliary organic anion transporters and bilirubin-conjugating enzyme in differentiating embryonic stem cells.

ABCC3 ABCC1

7.99e-05681212951053
Pubmed

Ion channel expression in the developing enteric nervous system.

KCNA2 KCNA4 KCNN2

8.93e-053781325798587
Pubmed

Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.

CLEC18A CLEC18B CLEC18C

8.93e-053781322432025
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

CDAN1 CLEC18A CLEC18B CLEC18C PODN LRRTM3 TLR8

1.01e-0446081720562862
Pubmed

Peroxisome synthesis in the absence of preexisting peroxisomes.

ABCD3 PEX11B

1.12e-0478129922452
Pubmed

Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

KCNA2 KCNA4

1.12e-04781218509034
Pubmed

Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

AXL TNK2

1.12e-04781219815557
Pubmed

Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

SASH1 APOE

1.12e-04781220061627
Pubmed

Pore size matters for potassium channel conductance.

KCNA2 KCNA4

1.12e-04781227619418
Pubmed

Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.

ABCC3 ABCC1

1.12e-04781220922799
Pubmed

Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.

KCNA2 KCNA4

1.12e-0478129852577
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 KCNA3 RPS13 ABCD3 LUZP1

1.29e-0420881533230847
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC1

1.49e-04881215802388
Pubmed

Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse.

ABCC1 ABCD3

1.91e-04981226122848
Pubmed

Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

KCNA2 KCNA3

1.91e-0498129488722
Pubmed

Statins improve NASH via inhibition of RhoA and Ras.

MAPK1 APOE

1.91e-04981227634010
Pubmed

Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1.

MFNG ADAM7

1.91e-04981215574878
Pubmed

GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity.

WHRN MYO15A

1.91e-04981230827920
Pubmed

Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling.

MAPK1 APOE

2.38e-041081226449752
Pubmed

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins.

ABCD3 PEX11B

2.38e-041081214709540
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 PIEZO1 FBXL12 CBLC TNK2 ATG2A HERC1 MCF2L ESPL1 KCNH3

2.45e-041105811035748872
Pubmed

An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.

LRRTM3 APOE

2.91e-041181219105203
Pubmed

CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.

WHRN MYO15A

3.48e-041281228663585
Pubmed

Erbb2 is required for cardiac atrial electrical activity during development.

MAPK1 PRPF8

3.48e-041281225269082
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

KCNA2 EFNB1 GPR158 ABCD3 LRRTM3 SLC4A3

3.74e-0440581638187761
Pubmed

Defining the membrane proteome of NK cells.

ABCC1 NDC1 QPCTL RPS13 ABCD3 TNK2 APOE PEX11B PRPF8 LUZP1

3.80e-041168811019946888
Pubmed

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.

TAS2R42 TAS2R50

4.11e-041381215938754
Pubmed

A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).

MYO15A ALDH3A2

4.11e-041381210049592
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NDC1 EFNB1 QPCTL AXL NOL6 ABCD3 PEX11B MED23 ALDH3A2 PRPF8

4.79e-041203811029180619
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

CNTNAP4 SLC4A3

4.79e-041481224811271
GeneFamilyPotassium voltage-gated channels

KCNA2 KCNH8 KCNA3 KCNA4 KCNH3

2.04e-0740605274
GeneFamilyC-type lectin domain family

CLEC18A CLEC18B CLEC18C

5.08e-0447603494
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC1

8.25e-0413602807
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ CLEC18A GPR158 GCLM KEL ISG20

6.38e-0716881608fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ CLEC18A GPR158 GCLM KEL ISG20

6.38e-07168816d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCellBronchial_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

NKX6-3 BRINP2 NDST4 FAM43B ESPL1 ADCY5

7.57e-07173816e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCellBronchial_Brush-Epithelial-Ionocytes|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

NKX6-3 BRINP2 NDST4 FAM43B ESPL1 ADCY5

7.57e-07173816f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

ABCC3 SASH1 AXL KRT222 DAPK1 APOE

9.54e-071808167be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CLEC18A CFAP251 BHLHA9 LRRC43 GLP2R

2.70e-06120815a6d0406a174d46ce06b41280292931954af88a59
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 SASH1 KRT222 KEL SLC4A3

1.10e-0516081556e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 SASH1 KRT222 KEL SLC4A3

1.10e-05160815bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 SASH1 AXL APOE MYO15A

1.10e-051608150544bc465af208da448858d6e174ff56f2e08a46
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GPR158 GCLM KEL ISG20

1.24e-0516481518eeda51e69722992c3a7f699be293535a90868b
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 GCLM KRT222 ISG20

1.69e-058481457d549d7c5786d2a74601595df3dc3776f8ff6ea
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

ABCC3 ABCC1 AXL CBLC LUZP1

1.84e-05178815441d1dba720141891b11f404744c59834d80e6c5
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC3 SASH1 AXL FAM167A APOE

1.84e-05178815c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC3 SASH1 AXL FAM167A APOE

1.89e-0517981513d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POMT2 CFAP251 OXTR DTHD1 KCNH3

1.94e-051808151f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POMT2 CFAP251 OXTR DTHD1 KCNH3

2.45e-05189815b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.C1ql3_(Hippocampus_Excitatory_Neuron)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLEC18A BHLHA9 KCNH3 GLP2R

2.97e-05978141da964954a95c497ac4a24df1ea3575df5747025
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLEC18A BHLHA9 KCNH3 GLP2R

2.97e-0597814dd188763ba02337e4f25d56766eda886cffa810d
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLEC18A BHLHA9 KCNH3 GLP2R

2.97e-0597814a0242258aad0766450ff52fe28278cbb2b8d63a0
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.C1ql3_(Hippocampus_Excitatory_Neuron)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLEC18A BHLHA9 KCNH3 GLP2R

2.97e-059781498a31b9bf0adcad1cb1d803bf7a23d49b4e1f2d5
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

DNHD1 ABCC3 DAPK1 APOE KCNH3

2.99e-0519781515b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

DNHD1 ABCC3 DAPK1 APOE KCNH3

2.99e-05197815a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC3 SASH1 AXL DAPK1 APOE

3.07e-051988159aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC3 SASH1 AXL DAPK1 APOE

3.07e-051988155aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCellmLN-Macrophage|mLN / Region, Cell class and subclass

SASH1 DAPK1 KEL APOE TLR8

3.22e-0520081568d709afd226241e002dae6d6820bccd1cfd87a1
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-05200815e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellmLN-(6)_Macrophage|mLN / shred on region, Cell_type, and subtype

SASH1 DAPK1 KEL APOE TLR8

3.22e-052008156dcba82a7d322102bae205543086e84c7655b3e0
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-05200815a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-0520081589a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-05200815b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-052008151d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-0520081558a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-05200815d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellControl_saline-Endothelial-Endothelial-Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC3 MFNG EFNB1 SASH1 LUZP1

3.22e-05200815abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-0520081560d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

MFNG EFNB1 SASH1 MCF2L LUZP1

3.22e-052008153372c488a39fe812fa94e4f0564594186fea3db5
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

KCNA3 BRINP2 CNTNAP4 DAPK1 SLC4A3

3.22e-05200815c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

WHRN UCN BHLHA9 GLP2R

5.99e-051168149c92e714e210a2f29a9e228653d4c990ec643c72
ToppCellSubstantia_nigra-Neuronal-Excitatory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLEC18A KCNA4 NDST4 MAPK1

6.40e-051188149f1d744f46d79ff2ab7f168f54fdbd9f4640dddd
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN OXTR SASH1 CNTNAP4

7.76e-05124814298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

PIGQ CFAP251 FBXL12 SLC4A3

1.02e-04133814e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Striatum / BrainAtlas - Mouse McCarroll V32

KCNA3 NDST4 CNTNAP4 PODN

1.02e-04133814d5326a6ccada5ae6d3e8f7d4a858c90050e23c5b
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNH8 SASH1 RBPJL APOE

1.21e-04139814a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

BHLHA9 MAPK1 ADCY5 KCNH3

1.46e-041468147b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CLEC18A UCN BHLHA9 MAPK1

1.54e-04148814223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCellVE-CD8-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

OXTR ISG20 MUC12 DTHD1

1.54e-04148814f49f579650b57cc4c6c7a7fa726447740d3dc695
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA4 MCF2L DTHD1 GLP2R

1.54e-04148814f58804d24fe524b42b5090c8658050ea4b14793e
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNA2 KCNA3 CYP4F22 APOE

1.79e-0415481444d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNHD1 ABCC3 KCNH8 QPCTL

1.97e-041588147f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 AXL DTHD1 TLR8

2.02e-04159814323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM7 LRRC43 DTHD1 KCNH3

2.02e-0415981400a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

FAM167A KCNN2 DAPK1 TLR8

2.28e-041648143c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 SASH1 AXL APOE

2.28e-04164814758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLEC18A OXTR KEL ESPL1

2.28e-04164814fb18b863152fb3109e2224c791c84c6371680a4e
ToppCellInt-URO-Myeloid-tDC|Int-URO / Disease, Lineage and Cell Type

CFAP251 QPCTL AXL SLC4A3

2.33e-041658149803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WHRN BRINP2 KEL ISG20

2.49e-0416881417fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA4 GPR158 ADAM7 KCNH3

2.49e-04168814b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 AXL FAM167A TLR8

2.49e-041688144ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WHRN BRINP2 KEL ISG20

2.49e-04168814a61b39884851384cffd430079040546d125b2b40
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA4 GPR158 ADAM7 KCNH3

2.49e-04168814b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 AXL FAM167A TLR8

2.49e-0416881404e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

DNHD1 CFAP251 KIF1B LPO

2.55e-04169814dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 AXL FAM167A TLR8

2.55e-04169814454b92b9b67299a64278c010db033ca5b9d217a0
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 AXL FAM167A TLR8

2.55e-0416981444d841fd997a6f26104f16cd00223ecce8352f43
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 GPR158 KRT222 ISG20

2.55e-04169814c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 AXL FAM167A TLR8

2.55e-04169814aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 SASH1 AXL APOE

2.61e-04170814067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCelltumor_Lung-Endothelial_cells-EPCs|Endothelial_cells / Location, Cell class and cell subclass

WHRN KCNA3 AXL KCNH3

2.67e-04171814dcb6c41980008d0b9eeb54999faff77311554976
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFNG NDC1 AXL ESPL1

2.67e-04171814d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC18A LRRTM3 APOE ADCY5

2.67e-041718144ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellInt-URO-Lymphocyte-T_NK-dnT|Int-URO / Disease, Lineage and Cell Type

WHRN NDC1 MUC12 DTHD1

2.73e-04172814e70299573da1679d6d286c3a43699cbff76e207d
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AXL PODN DAPK1 APOE

2.85e-04174814cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNA3 AXL APOE ESPL1

2.85e-0417481433e5903adb746f693433bdca11a75c508bbf50c0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNA3 AXL APOE ESPL1

2.85e-04174814ca0c2f42544092848541863c4a47b334e6828b8a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

2.85e-0417481481ab196e36cac2a7974d6e3fe457efffddfd03bb
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

KCNH8 KCNA4 FFAR1 LRRTM3

2.91e-041758144db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

KCNH8 KCNA4 FFAR1 LRRTM3

2.91e-041758148d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCelldroplet-Marrow-nan-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

2.98e-04176814f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

OXTR PODN FAM43B GLP2R

2.98e-04176814135d51d28a7ad2a67d5a6c49eb6e661f4beb66f5
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

OXTR PODN FAM43B GLP2R

2.98e-041768142287bd8382f41e36ebb0875a0133bada1ec81fa7
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 AXL BHLHA9 SLC4A3

2.98e-041768145e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AXL FAM167A APOE

3.04e-0417781443883b65b1e03043a24fc40c84c50bac81960c12
ToppCelldroplet-Lung-LUNG-30m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AXL FAM167A APOE

3.04e-041778149de6a82b7fb72d20361947f7ac95bb1fa73fc2ff
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNA2 KCNH8 OXTR KCNN2

3.04e-0417781459cf56c385c324f0844f20003d2b5049a2791e45
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SASH1 AXL APOE

3.04e-0417781426bad614560609d318bfc9c235a698bca4e1c22c
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 AXL BHLHA9 SLC4A3

3.04e-0417781414fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WHRN DAPK1 ISG20 ALDH3A2

3.04e-041778142dd6dd5193bda9ba1c6b299ec47890fdc92f88b1
ToppCelldroplet-Marrow-nan-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

3.11e-04178814b4e15c176875cd226854a0019495309d02730c42
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A KCNH8 CNTNAP4 KCNH3

3.11e-04178814445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A KCNN2 MYO15A LRRC43

3.11e-0417881458857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 KCNA2 SASH1 AXL

3.11e-041788146c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCelldroplet-Spleen-nan-24m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

3.11e-041788149c4950357087212b2388116ba8866c359628694d
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A KCNN2 MYO15A LRRC43

3.11e-041788148b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A KCNN2 MYO15A LRRC43

3.11e-04178814b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP2 KCNA2 FAM167A ADCY5

3.17e-04179814d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

3.17e-04179814f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP2 KCNA2 FAM167A ADCY5

3.17e-041798146be47c877250968a916c711ba0787eb7b4c5443d
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

3.17e-041798147e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ GCLM KEL ISG20

3.17e-0417981401e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SASH1 AXL DAPK1 TLR8

3.24e-041808147af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
Drugglibenclamide

ABCC3 ABCC1 KCNA2 KCNA3 UCN KCNN2 APOE MED23 ADCY5

7.78e-06382809CID000003488
Drugharmol sulfate

ABCC3 ABCC1 MCF2L

1.16e-0513803CID005488302
Drugclofibrate

ABCC3 ABCD3 CYP4F22 APOE PEX11B MCF2L ALDH3A2 ADCY5

1.37e-05311808CID000002796
Drugdiazoxide

ABCC1 KCNA2 KCNA3 KCNA4 FFAR1 KCNN2 MED23

1.53e-05227807CID000003019
Drugiodide

CDAN1 KCNA2 KCNA3 OXTR UCN LPO KEL APOE ADCY5 GLP2R

1.75e-055348010CID000024841
Diseasecys-gly, oxidized measurement

ABCC1 CDK10

7.22e-055802EFO_0800122
DiseaseHbA1c measurement

ABCC1 KCNA4 AXL PIEZO1 KEL APOE MCF2L MYO15A ADCY5

8.88e-05675809EFO_0004541
Diseasepyruvate measurement

CLEC18A SASH1 ARMC5 CLEC18C ISG20 PRDM15

9.09e-05268806EFO_0010117
Diseasesensorineural hearing loss (is_implicated_in)

WHRN APOE MYO15A

9.87e-0533803DOID:10003 (is_implicated_in)
DiseaseCognition Disorders

OXTR RAB40AL APOE

1.51e-0438803C0009241
Diseasecoagulation factor XA measurement

WHRN ABCC1

3.93e-0411802EFO_0020266
Diseasegastric ulcer (implicated_via_orthology)

OXTR MAPK1

6.47e-0414802DOID:10808 (implicated_via_orthology)
DiseaseZellweger Syndrome

ABCD3 PEX11B

8.50e-0416802C0043459
DiseaseHypertensive disease

ABCC1 UCN APOE ADCY5

1.80e-03190804C0020538
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

CBLC APOE

2.26e-0326802OBA_2045194
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

CBLC APOE

2.26e-0326802OBA_2045191
Diseasehearing impairment

WHRN APOE MYO15A

2.43e-0398803C1384666

Protein segments in the cluster

PeptideGeneStartEntry
LLARLRKDTHRGLFI

DAPK1

661

P53355
HASDLNLLTRRKLSR

DAPK1

1301

P53355
LSFRSLLELRRTIAH

SLC4A3

366

P48751
ASHLRKLRKRLLRDA

APOE

156

P02649
RLRRQLAKLAIIFSH

CBLC

116

Q9ULV8
NRKTLVLHLLRSREF

ADAM7

66

Q9H2U9
LSKIATLRRAIHRIA

BHLHA9

101

Q7RTU4
RAAKALLARARTLHL

GCLM

6

P48507
HITLQLRRARLFLLI

CNTNAP4

231

Q9C0A0
RIINLRHFKRILSLL

ALDH3A2

281

P51648
SRALLALRTRHIKAA

ARMC5

41

Q96C12
ARILHSLLDLHLRLK

DNHD1

2221

Q96M86
RLRSEHVRKFLLTFR

ADCY5

731

O95622
IFTLLLRLHRSLVLS

CDAN1

716

Q8IWY9
KEFLVTLRLHKATLR

ATG2A

1061

Q2TAZ0
KRFIHRDLAARNLLL

TNK2

246

Q07912
RLRSHRKSIRSLLFG

CFAP251

736

Q8TBY9
ADKRKHFRLVLRLVL

RBPJL

161

Q9UBG7
SFTELARIVLLRHRL

RAB40AL

166

P0C0E4
RLRSIEKRLHRLNLL

QPCTL

291

Q9NXS2
RRVSLRVLSERLLHK

ISG20

126

Q96AZ6
LARALLRKSRILVLD

ABCC3

1436

O15438
AHLLKTVRLLRLLRL

KCNH3

331

Q9ULD8
QRTLREIKILLRFRH

MAPK1

66

P28482
VHRDAFRKLRLLRSL

PODN

421

Q7Z5L7
IRLVRVFRIFKLSRH

KCNA2

296

P16389
RFRSLRHKIILLQSR

MYO15A

1921

Q9UKN7
LKLHRVLKVFLSRTA

GPR158

501

Q5T848
LGHRRALFEKRKRLS

KCNN2

121

Q9H2S1
LLHEVEKTRHFLLLR

KIF1B

1501

O60333
LARAHKARALARLLR

FAM43B

181

Q6ZT52
VTRRHKFDLAARTLL

HERC1

2876

Q15751
LKLFTHLRQDLERVR

JADE2

466

Q9NQC1
RLRKKSVSLRFDLHL

KRT222

241

Q8N1A0
FLREHNRLARELKRL

LPO

386

P22079
LRDRAFLKRKLVHAI

MED23

1016

Q9ULK4
RLRETEILFHSSLLR

NOL6

71

Q9H6R4
IRLVRVFRIFKLSRH

KCNA3

366

P22001
KLRRSFRTLIVLLAT

NDST4

6

Q9H3R1
LLALRTTRQKHSRLF

OXTR

61

P30559
LLLLRIVSERLKDHS

ESPL1

796

Q14674
ALTLLLFLRKLHCTR

GLP2R

196

O95838
LRALARSGLTHRRKL

FFAR1

206

O14842
ISSLREITLLLRLRH

CDK10

81

Q15131
IFLTVLLLKLRKRHR

EFNB1

256

P98172
TFTDKLRLLARHLRK

DTHD1

736

Q6ZMT9
LRLLARHLRKIGRSD

DTHD1

741

Q6ZMT9
LRFKLQSLSRRLDEL

LUZP1

16

Q86V48
RGLLSKSLELHRRLE

MCF2L

451

O15068
RQLESHLSLGRKLLR

PEX11B

46

O96011
LTLLRFRLSVDRTRK

CYP4F22

491

Q6NT55
KTTRAFHRLRLELLL

MFNG

61

O00587
VTSLRTLRHLRLLVL

LRRC43

241

Q8N309
VSLKRLRIFLSHEEL

ABCC1

611

P33527
HLRSLKALTEKLRLE

FAM167A

26

Q96KS9
LFLFLSLVRHTRNLK

TAS2R42

201

Q7RTR8
LLFLHLKRRVRSVIL

TAS2R50

116

P59544
RIKVLRSRIRFIHLV

POMT2

466

Q9UKY4
LRKLLSLHLRSNSLR

LRRTM3

156

Q86VH5
LLLRKHRAAFSVLSL

NKX6-3

246

A6NJ46
RLLFLLSLLHTDIRS

RIC8B

166

Q9NVN3
LKRSLILSSRHGIRR

PRDM15

711

P57071
LAISRHLRDVRKIRL

FBXL12

221

Q9NXK8
RHRLEHLTLIFSTRK

PIGQ

251

Q9BRB3
EAVRLLKSSRHLILT

WHRN

341

Q9P202
LLLCLLHKRRRALGL

ABCD3

21

P28288
VRLDLFSCLLRHRLK

BRINP2

736

Q9C0B6
KESFLLLSLHNRLRS

CLEC18A

46

A5D8T8
KESFLLLSLHNRLRS

CLEC18B

46

Q6UXF7
KESFLLLSLHNRLRS

CLEC18C

46

Q8NCF0
TAFSRLILILRALHV

PRPF8

1931

Q6P2Q9
RNFSKLLSLRALHLR

TLR8

361

Q9NR97
AKFRLILIESRIHRL

RPS13

111

P62277
ILALFLVHRRKKETR

AXL

466

P30530
RHIRKLLSAARLFKL

SASH1

1226

O94885
VLSRTSKFRRLRELL

nan

311

A8MUI8
LRRLLELHVFKLVAL

PIEZO1

806

Q92508
KILVLHLKRFSESRI

USP2

496

O75604
LTFHLLRTLLELART

UCN

91

P55089
KLFTAIRDALITRLR

KEL

441

P23276
IRLVRVFRIFKLSRH

KCNA4

446

P22459
LVHLLKTVRLLRLLR

KCNH8

326

Q96L42
ILIILFSLSQRKRHR

MUC12

5396

Q9UKN1
KFLRFRRSLLLLVKH

NDC1

201

Q9BTX1