Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB2 AXL INSR INSRR RET IGF1R EPHA2 ROS1 EPHA5

7.20e-08652379GO:0004714
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB2 AXL INSR INSRR RET IGF1R EPHA2 ROS1 EPHA5

7.55e-07852379GO:0019199
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB2 AXL INSR INSRR BCR RET IGF1R CSK EPHA2 ROS1 EPHA5

1.31e-0614523711GO:0004713
GeneOntologyMolecularFunctioninsulin receptor activity

INSR INSRR IGF1R

1.65e-0632373GO:0005009
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 BCR MAP3K1 PIK3R4 CIITA PIK3CB PI4KA EIF2AK3 MAP3K19 SIK3 RET PAPSS2 TKFC IGF1R CSK EPHA2 ROS1 STK40 EPHA5

4.22e-0670923724GO:0016773
GeneOntologyMolecularFunctionkinase activity

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 BCR MAP3K1 PIK3R4 SGMS1 CIITA PIK3CB PI4KA EIF2AK3 MAP3K19 SIK3 RET PAPSS2 TKFC IGF1R CSK EPHA2 ROS1 STK40 EPHA5

4.77e-0676423725GO:0016301
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 BCR MAP3K1 PIK3R4 SGMS1 CIITA PIK3CB PI4KA EIF2AK3 MAP3K19 TUT4 SIK3 RET SIRT6 TEP1 PAPSS2 TKFC IGF1R CSK EPHA2 ROS1 STK40 EPHA5

7.09e-0693823728GO:0016772
GeneOntologyMolecularFunctionprotein kinase activity

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 BCR MAP3K1 PIK3R4 CIITA PIK3CB EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 ROS1 STK40 EPHA5

1.05e-0560023721GO:0004672
GeneOntologyMolecularFunctioninsulin receptor substrate binding

INSR INSRR PIK3CB IGF1R

2.38e-05152374GO:0043560
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRR1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 TMEM63C GRIA4 GRIK1 GRIK2

1.08e-0419323710GO:0015276
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 CACNG1 TMEM63C GRIA4 ATP5MF GRIK1 GRIK2 PKD2L2 UNC80

1.27e-0445923716GO:0005216
GeneOntologyMolecularFunctionligand-gated channel activity

GABRR1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 TMEM63C GRIA4 GRIK1 GRIK2

1.27e-0419723710GO:0022834
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase binding

AXL ESR1 INSR INSRR IGF1R

1.50e-04432375GO:0043548
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GABRR1 GRIA4 GRIK1 GRIK2

1.71e-04242374GO:0099507
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A PKD1L1 RYR2 RYR3 TRPM5 CHRNA6 CACNG1 TMEM63C ATP5MF GRIK1 GRIK2 PKD2L2 UNC80

2.46e-0434323713GO:0005261
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

LRRK2 MAP3K20 MAP3K1 MAP3K19

2.74e-04272374GO:0004709
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

LRRK2 MAP3K20 MAP3K1

3.36e-04122373GO:0004706
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

INSR IGF1R LRP2

4.32e-04132373GO:0031994
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

PKD1L1 RYR2 RYR3 TRPM5 CACNG1 GRIK1 SLC8A3 PKD2L2

4.53e-041512378GO:0015085
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR2 RYR3 TRPM5 GRIK1

4.73e-04312374GO:0099604
GeneOntologyMolecularFunctionchannel activity

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 CACNG1 TMEM63C GRIA4 ATP5MF GRIK1 GRIK2 PKD2L2 UNC80

5.66e-0452523716GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 CACNG1 TMEM63C GRIA4 ATP5MF GRIK1 GRIK2 PKD2L2 UNC80

5.77e-0452623716GO:0022803
GeneOntologyMolecularFunctionstalled ribosome sensor activity

MAP3K20 GCN1

8.29e-0442372GO:0170011
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

8.29e-0442372GO:0005219
GeneOntologyMolecularFunctioncalcium channel activity

PKD1L1 RYR2 RYR3 TRPM5 CACNG1 GRIK1 PKD2L2

8.91e-041292377GO:0005262
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA4 GRIK1 GRIK2

9.93e-04172373GO:0004970
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRR1 CHRNA6 GRIA4 GRIK1 GRIK2

1.04e-03652375GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRR1 CHRNA6 GRIA4 GRIK1 GRIK2

1.04e-03652375GO:0022824
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRR1 CHRNA6 DRD5 GRIA4 GRIK1 GRIK2

1.24e-031002376GO:0030594
GeneOntologyMolecularFunctioninsulin binding

INSR IGF1R

1.37e-0352372GO:0043559
GeneOntologyMolecularFunctioninsulin-like growth factor binding

INSR IGF1R LRP2

1.39e-03192373GO:0005520
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

RYR2 RYR3 TRPM5 CHRNA6 TMEM63C GRIK1 GRIK2

1.43e-031402377GO:0099094
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

CHRNA6 DRD5 GRIA4 GRIK1 GRIK2

1.98e-03752375GO:0098960
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2

2.04e-0362372GO:0015277
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.04e-0362372GO:0048763
GeneOntologyMolecularFunctionprotein-hormone receptor activity

INSR INSRR IGF1R

2.15e-03222373GO:0016500
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRR1 CHRNA6 GRIA4 GRIK1 GRIK2

2.23e-03772375GO:0005230
GeneOntologyMolecularFunctiongated channel activity

GABRR1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 CACNG1 TMEM63C GRIA4 GRIK1 GRIK2

2.25e-0333423711GO:0022836
GeneOntologyCellularComponentinsulin receptor complex

INSR INSRR IGF1R

5.22e-0642303GO:0005899
GeneOntologyCellularComponentsodium channel complex

SCN11A GRIA4 GRIK1 GRIK2 UNC80

1.48e-05292305GO:0034706
GeneOntologyCellularComponentreceptor complex

GABRR1 ERBB2 AXL INSR INSRR PLXNB1 CHRNA6 ITGA11 GRIA4 GRIK1 GRIK2 RET CR2 IGF1R EPHA2 TM7SF2 LRP2 ROS1 EPHA5

2.52e-0558123019GO:0043235
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIA4 GRIK1 GRIK2

2.57e-0562303GO:0032983
GeneOntologyCellularComponentsarcolemma

ESR1 RTN2 ADCY6 RYR2 RYR3 ALOX12 CACNG1 SYNM SLC8A3 IGF1R

5.06e-0519023010GO:0042383
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 CHRNA6 BEST1 CACNG1 GRIA4 ATP5MF GRIK1 GRIK2 UNC80

8.22e-0537823014GO:0034702
GeneOntologyCellularComponentcell projection membrane

ERBB2 PKD1L1 INSR ADCY6 PIK3CB PTPRZ1 EPS8L2 DRD5 ACE2 TIRAP EPHA2 LRP2 MACF1 ENPEP DMTN

9.21e-0543123015GO:0031253
GeneOntologyCellularComponentmembrane protein complex

GABRR1 SCN11A ERBB2 CLTCL1 GPAA1 HLA-DQB1 PKD1L1 INSR NOXA1 INSRR MYCBPAP RYR2 RYR3 STT3A PIK3R4 TRPM5 AP1B1 PIK3CB COX4I2 TIMM44 CHRNA6 BEST1 ITGA11 CACNG1 SYNE1 GRIA4 ATP5MF GRIK1 GRIK2 SEC31A RET IGF1R UNC80

1.05e-04149823033GO:0098796
GeneOntologyCellularComponentcation channel complex

SCN11A PKD1L1 RYR2 RYR3 CACNG1 GRIA4 ATP5MF GRIK1 GRIK2 UNC80

2.89e-0423523010GO:0034703
GeneOntologyCellularComponenttransmembrane transporter complex

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 COX4I2 CHRNA6 BEST1 CACNG1 GRIA4 ATP5MF GRIK1 GRIK2 UNC80

7.20e-0452323015GO:1902495
GeneOntologyCellularComponentneuronal cell body

SCN11A ESR1 INSR LRRK2 ERMN TRPM5 PTPRZ1 DRD5 ENC1 PUM2 GRIA4 GRIK1 GRIK2 RET SLC8A3 IGF1R SLC4A10 ASTN1 RAPGEF2 EPHA5

9.63e-0483523020GO:0043025
GeneOntologyCellularComponenttransporter complex

GABRR1 SCN11A PKD1L1 RYR2 RYR3 TRPM5 COX4I2 CHRNA6 BEST1 CACNG1 GRIA4 ATP5MF GRIK1 GRIK2 UNC80

1.19e-0355023015GO:1990351
GeneOntologyCellularComponentruffle membrane

ERBB2 PTPRZ1 EPS8L2 TIRAP EPHA2 MACF1

1.25e-031082306GO:0032587
DomainTyr_kinase_cat_dom

ERBB2 AXL INSR INSRR RET IGF1R CSK EPHA2 ROS1 EPHA5

1.39e-078823210IPR020635
DomainTyrKc

ERBB2 AXL INSR INSRR RET IGF1R CSK EPHA2 ROS1 EPHA5

1.39e-078823210SM00219
DomainPROTEIN_KINASE_TYR

ERBB2 AXL INSR INSRR RET IGF1R CSK EPHA2 ROS1 EPHA5

3.52e-079723210PS00109
DomainTyr_kinase_AS

ERBB2 AXL INSR INSRR RET IGF1R CSK EPHA2 ROS1 EPHA5

3.52e-079723210IPR008266
DomainPkinase_Tyr

ERBB2 AXL INSR INSRR MAP3K20 RET IGF1R CSK EPHA2 ROS1 EPHA5

6.30e-0712923211PF07714
DomainRecep_L_domain

ERBB2 INSR INSRR IGF1R

7.89e-0772324PF01030
DomainFurin-like

ERBB2 INSR INSRR IGF1R

7.89e-0772324PF00757
DomainRcpt_L-dom

ERBB2 INSR INSRR IGF1R

7.89e-0772324IPR000494
DomainFurin-like_Cys-rich_dom

ERBB2 INSR INSRR IGF1R

7.89e-0772324IPR006211
Domain-

ERBB2 INSR INSRR IGF1R

7.89e-07723243.80.20.20
DomainKinase-like_dom

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 MAP3K1 PIK3R4 ACAD11 PIK3CB PI4KA EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 MACF1 ROS1 STK40 EPHA5

1.20e-0654223222IPR011009
DomainSer-Thr/Tyr_kinase_cat_dom

ERBB2 AXL INSR INSRR MAP3K20 RET IGF1R CSK EPHA2 ROS1 EPHA5

1.24e-0613823211IPR001245
DomainTyr_kinase_insulin-like_rcpt

INSR INSRR IGF1R

1.89e-0632323IPR016246
DomainTyr_kinase_rcpt_2_CS

INSR INSRR IGF1R ROS1

7.15e-06112324IPR002011
DomainRECEPTOR_TYR_KIN_II

INSR INSRR IGF1R ROS1

1.06e-05122324PS00239
DomainPROTEIN_KINASE_ATP

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 MAP3K1 PIK3R4 EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 ROS1 STK40 EPHA5

1.84e-0545923218PS00107
DomainARM-type_fold

CLTCL1 LRRK2 LYST MAP3K1 RYR3 PIK3R4 AP1B1 PIK3CB PI4KA GCN1 HEATR4 MROH2A PUM2 NBEA BTAF1

2.36e-0533923215IPR016024
DomainProt_kinase_dom

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 MAP3K1 PIK3R4 EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 ROS1 STK40 EPHA5

4.23e-0548923218IPR000719
DomainPROTEIN_KINASE_DOM

ERBB2 AXL INSR INSRR LRRK2 MAP3K20 MAP3K1 PIK3R4 EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 ROS1 STK40 EPHA5

4.70e-0549323218PS50011
DomainFurin_repeat

ERBB2 INSR INSRR IGF1R

6.19e-05182324IPR006212
DomainFU

ERBB2 INSR INSRR IGF1R

6.19e-05182324SM00261
DomainProtein_kinase_ATP_BS

ERBB2 AXL INSR INSRR LRRK2 MAP3K1 EIF2AK3 MAP3K19 SIK3 RET IGF1R CSK EPHA2 ROS1 EPHA5

8.38e-0537923215IPR017441
DomainFN3

AXL INSR INSRR PTPRZ1 IGF1R EPHA2 ASTN1 EGFLAM ROS1 EPHA5

1.10e-0418523210SM00060
DomainPax7_C

PAX3 PAX7

1.54e-0422322IPR022106
DomainPax7

PAX3 PAX7

1.54e-0422322PF12360
DomainEIF3C_N_dom

EIF3CL EIF3C

1.54e-0422322IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

1.54e-0422322PF05470
DomainEIF3C

EIF3CL EIF3C

1.54e-0422322IPR027516
Domainfn3

AXL INSR INSRR PTPRZ1 IGF1R EPHA2 EGFLAM ROS1 EPHA5

1.97e-041622329PF00041
DomainFN3

AXL INSR INSRR PTPRZ1 IGF1R EPHA2 ASTN1 EGFLAM ROS1 EPHA5

1.99e-0419923210PS50853
Domain-

WDR64 LRRK2 LYST PIK3R4 PLXNB1 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11 HPS5

2.84e-04333232132.130.10.10
DomainFN3_dom

AXL INSR INSRR PTPRZ1 IGF1R EPHA2 ASTN1 EGFLAM ROS1 EPHA5

2.95e-0420923210IPR003961
DomainWD40/YVTN_repeat-like_dom

WDR64 LRRK2 LYST PIK3R4 PLXNB1 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11 HPS5

3.01e-0433523213IPR015943
DomainWD40_repeat_dom

WDR64 LRRK2 LYST PIK3R4 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11 HPS5

3.57e-0429723212IPR017986
DomainRyanodine_rcpt

RYR2 RYR3

4.57e-0432322IPR003032
DomainDishevelled_C-dom

DVL2 DVL3

4.57e-0432322IPR024580
DomainRyanrecept_TM4-6

RYR2 RYR3

4.57e-0432322IPR009460
DomainDsh_C

DVL2 DVL3

4.57e-0432322PF12316
DomainRyR

RYR2 RYR3

4.57e-0432322PF02026
DomainRR_TM4-6

RYR2 RYR3

4.57e-0432322PF06459
DomainRyan_recept

RYR2 RYR3

4.57e-0432322IPR013333
DomainWD40

WDR64 LRRK2 LYST PIK3R4 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11

5.48e-0426823211SM00320
DomainWD40_repeat

WDR64 LRRK2 LYST PIK3R4 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11

6.20e-0427223211IPR001680
DomainDishevelled

DVL2 DVL3

9.07e-0442322PF02377
DomainDsh/Dvl-rel

DVL2 DVL3

9.07e-0442322IPR015506
DomainDishevelled_fam

DVL2 DVL3

9.07e-0442322IPR008339
DomainDishevelled_protein_dom

DVL2 DVL3

9.07e-0442322IPR003351
DomainLig_chan-Glu_bd

GRIA4 GRIK1 GRIK2

1.34e-03182323PF10613
DomainGlu/Gly-bd

GRIA4 GRIK1 GRIK2

1.34e-03182323IPR019594
DomainLig_chan-Glu_bd

GRIA4 GRIK1 GRIK2

1.34e-03182323SM00918
DomainIontro_rcpt

GRIA4 GRIK1 GRIK2

1.34e-03182323IPR001320
DomainIono_rcpt_met

GRIA4 GRIK1 GRIK2

1.34e-03182323IPR001508
DomainLig_chan

GRIA4 GRIK1 GRIK2

1.34e-03182323PF00060
DomainPBPe

GRIA4 GRIK1 GRIK2

1.34e-03182323SM00079
DomainDZF

ZFR2 ZFR

1.50e-0352322SM00572
DomainDZF_dom

ZFR2 ZFR

1.50e-0352322IPR006561
DomainDZF

ZFR2 ZFR

1.50e-0352322PF07528
DomainDZF

ZFR2 ZFR

1.50e-0352322PS51703
DomainWD40

WDR64 LYST PIK3R4 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11

1.54e-0325923210PF00400
DomainHEAT_REPEAT

PIK3R4 GCN1 HEATR4 MROH2A BTAF1

1.78e-03702325PS50077
DomainAdcy_conserved_dom

ADCY2 ADCY6

2.23e-0362322IPR009398
DomainRIH_assoc-dom

RYR2 RYR3

2.23e-0362322IPR013662
Domain-

EPPK1 MACF1

2.23e-03623223.90.1290.10
DomainPH_BEACH

LYST NBEA

2.23e-0362322PF14844
DomainGATASE_TYPE_1

PFAS CPS1

2.23e-0362322PS51273
DomainDUF1053

ADCY2 ADCY6

2.23e-0362322PF06327
DomainIns145_P3_rec

RYR2 RYR3

2.23e-0362322PF08709
DomainGATASE

PFAS CPS1

2.23e-0362322IPR017926
DomainRIH_assoc

RYR2 RYR3

2.23e-0362322PF08454
DomainRIH_dom

RYR2 RYR3

2.23e-0362322IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

2.23e-0362322IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

2.23e-0362322IPR015925
Domain-

RYR2 RYR3

2.23e-03623221.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

2.23e-0362322PF01365
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PFAS BCR ADCY6 PIK3R4 DNAJC10 ACAD11 AP1B1 TONSL KMT2A KYNU PLXNB1 GPAM ATP5MF BTAF1 SIK3 PAPSS2 PWP1 ACE2 ELP2 HPS5 CMTR2 AQR HR

1.82e-106502392338777146
Pubmed

The protein tyrosine kinase family of the human genome.

ERBB2 AXL INSR INSRR RET IGF1R CSK EPHA2 ROS1 EPHA5

3.05e-10832391011114734
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

ERBB2 INSR INSRR RET IGF1R EPHA2 EPHA5

1.02e-0840239730898150
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERBB2 EPPK1 CLTCL1 PER1 PFAS BCR LYST TBC1D9 KIAA2013 PI4KA A4GALT JOSD1 GCN1 ABTB2 NSD1 BTAF1 TEP1 ZNF865 NHSL1 TKFC IGF1R KLHL25 GAREM2 TTLL4 STK40 MYBL2 HR

1.40e-0811052392735748872
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ERBB2 INSR INSRR BCR RET CR2 IGF1R TM7SF2 LRP2

3.54e-08101239923382219
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ERBB2 STARD10 INSR FNBP1L BCR BDH1 STT3A SGMS1 SPIN1 GLYR1 ARHGAP8 BEST1 TUT4 ENC1 CXXC5 TMEM63C RNF213 PPHLN1 GRIK1 GRIK2 BTAF1 H6PD TEP1 DNTTIP1 ARHGAP6 IGF1R MACF1 RAPGEF2 HPS5 MCTP2 CUX1

4.37e-0814892393128611215
Pubmed

Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice.

SYNM IGF1R KLHL25 ST8SIA2 MCTP2

1.17e-0718239531541165
Pubmed

Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.

ERBB2 RET IGF1R EPHA2

2.67e-079239424285539
Pubmed

Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.

GRIA4 GRIK1 GRIK2

3.20e-07323931379666
Pubmed

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

ERBB2 ESR1 IGF1R

3.20e-073239328498399
Pubmed

Insulin receptor-related receptor as an extracellular alkali sensor.

INSR INSRR IGF1R

3.20e-073239321641549
Pubmed

Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.

INSR INSRR IGF1R

3.20e-073239321681845
Pubmed

C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor.

INSR IGF1R CSK

1.28e-064239310026153
Pubmed

The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice.

ERBB2 INSR RET

1.28e-06423939342439
Pubmed

Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways.

LRRK2 DVL2 DVL3

1.28e-064239319625296
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

SRRM1 ERBB2 ESR1 INSR INSRR PPM1L HEATR4 BTAF1 RET IGF1R EPHA2 ZFR UNC80 EPHA5

1.49e-064202391428065597
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

SRRM1 AXL INSR MAP3K20 BCR LYST MAP3K1 EIF3CL PIK3R4 ACAD11 AP1B1 OSBPL8 KMT2A SIK3 RET CCNT1 GTF2H1 IGF1R CSK EPHA2 EIF3C

1.54e-069102392136736316
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

HLA-DQB1 PKD1L1 ETV4 TMEM104 RYR3 ABCB4 PRDM11 PTPRZ1 ACCS C4orf33 RET CR2 PLPP6 SLC8A3 OVGP1 SLC16A6 TIRAP SLC25A44 EIF3C ZBTB3 CMTR2

1.68e-069152392132393512
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ESR1 BMS1 MAP3K20 BDH1 KIAA2013 ACAD11 PI4KA OSBPL8 KMT2A GEMIN2 SYNE1 CXXC5 NSD1 PUM2 PPHLN1 ATP5MF PNISR PLPP6 DNTTIP1 IWS1 PWP1 CCNT1 GTF2H1 PALM3 PPP1R18 MACF1 EIF3C AQR

1.72e-0614972392831527615
Pubmed

GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor neuron pools.

MNX1 ETV4 RET PAX3

2.06e-0614239412372284
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SRRM1 INSR LRRK2 BMS1 RYR2 PI4KA GCN1 SYNM GPATCH1 RNF213 NBEA SEC31A ZNF865 EEF2 EPHA2 ZFR RAPGEF2 CUX1 RPL17

2.15e-067772391935844135
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

ERBB2 ESR1 INSR BCR ADH1C ALOX12 GPX3 RET TEP1 IGF1R ROS1 CXCR1 MYBL2

2.25e-063742391319625176
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

ERBB2 ESR1 INSR BCR ADH1C ALOX12 GPX3 RET TEP1 IGF1R ROS1 CXCR1 MYBL2

2.76e-063812391318676680
Pubmed

The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.

INSR INSRR IGF1R

3.17e-065239319001411
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA4 GRIK1 GRIK2

3.17e-06523931717158
Pubmed

Insulin-like growth factor-2 (IGF-2) activates estrogen receptor-α and -β via the IGF-1 and the insulin receptors in breast cancer cells.

ESR1 INSR IGF1R

3.17e-065239321410323
Pubmed

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

ERBB2 ESR1 STARD10

3.17e-065239319676041
Pubmed

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.

MNX1 DVL2 DVL3 RET

3.71e-0616239422771245
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ADCY6 OSBPL8 GCN1 CUX2 SYNE1 PUM2 SIK3 MACF1 HPS5 UNC80

4.01e-062252391012168954
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PER1 BCR BDH1 RYR2 EIF3CL HSPA12A PI4KA GLYR1 OSBPL8 TIMM44 GCN1 TUT4 DVL2 DVL3 GRIA4 ATP5MF NBEA IDH3A NHSL1 SLC4A10 MACF1 ASTN1 EIF3C

4.49e-0611392392336417873
Pubmed

Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression.

SIRT6 PAX3 PAX7

6.31e-066239335859073
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR2 RYR3 EIF2AK3

6.31e-066239319009018
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

ERBB2 ESR1 ABCB4 ADH1C ACCS ALOX12 GPAM GRIK1 RET IGF1R CSK CXCR1

6.56e-063512391220453000
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

ERBB2 ESR1 INSR BCR ADH1C ALOX12 GPX3 RET TEP1 IGF1R ROS1 CXCR1 MYBL2

8.09e-064212391319692168
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ERBB2 INSR HSPA12A STXBP3 PI4KA OSBPL8 VAT1 SEC31A NHSL1 IGF1R EPHA2 MACF1 PRKCSH

8.09e-064212391336976175
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SRRM1 ACLY BMS1 MAP3K20 BDH1 MAP3K1 ACAD11 AP1B1 SPIN1 GLYR1 A4GALT OSBPL8 KMT2A TIMM44 LBHD1 GCN1 GEMIN2 PPHLN1 VARS2 DNTTIP1 PWP1 EEF2 TKFC EPHA2 ROS1

9.89e-0613712392536244648
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

INSR MEIS2 PTPRZ1 PLXNB1 CUX2 RET IGF1R PAX3 CUX1 EPHA5

1.05e-052512391029031500
Pubmed

New targetable oncogenes in non-small-cell lung cancer.

ERBB2 RET ROS1

1.10e-057239323401445
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA4 GRIK1 GRIK2

1.10e-05723939016303
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA4 GRIK1 GRIK2

1.10e-05723939651535
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIA4 GRIK1 GRIK2

1.10e-05723931310861
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

MAP3K20 PER1 BCR MAP3K1 PIK3R4 HROB STXBP3 AP1B1 ABTB2 ATG16L1 EPS8L2 GEMIN2 DVL2 DVL3 SEC31A PNISR DNTTIP1 IWS1 TTLL4 EIF3C RAPGEF2

1.16e-0510382392126673895
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

ACLY STT3A AP1B1 TIMM44 GCN1 GCFC2 SYNM BTAF1 IDH3A SIRT6 IWS1 PWP1 EEF2 ZFR ELP2 EIF3C

1.36e-056532391633742100
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPPK1 CLTCL1 ZMPSTE24 ACLY STARD10 STXBP3 AP1B1 TONSL KMT2A GCN1 KYNU VAT1 SYNE1 PAPSS2 EEF2 MACF1 PRKCSH RPL17

1.39e-058072391830575818
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ERBB2 PELI3 INSR STT3A EIF3CL AP1B1 KMT2A TUT4 DNAH2 NSD1 SIK3 OVGP1 IGF1R CSK LRP2 EIF3C RPL17

1.40e-057302391734857952
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

ERBB2 ESR1 INSR BCR ADH1C ALOX12 GPX3 RET TEP1 IGF1R ROS1 MYBL2

1.53e-053822391219170196
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ERBB2 ZMPSTE24 GPAA1 AXL ADCY6 STT3A STXBP3 KYNU ABHD16A RNF213 BTAF1 SEC31A CCNT1 TKFC SLC16A6 EPHA2 SLC4A10 MACF1 PRKCSH FITM2 CUX1

1.60e-0510612392133845483
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIA4 GRIK1 GRIK2

1.75e-05823938163463
Pubmed

Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.

INSR INSRR IGF1R

1.75e-058239315629149
Pubmed

RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells.

GCN1 EEF2 CSK EPHA2 RPL17

1.78e-0547239529212245
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

BMS1 STXBP3 SPIN1 GCN1 GCFC2 DCUN1D5 GPATCH1 CCNT1 CUX1

1.97e-05215239935973513
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SRRM1 SCN11A CLTCL1 ZMPSTE24 STARD10 FNBP1L NEB LYST ADCY6 RYR2 KIAA2013 ABCB4 DNAJC10 KMT2A VAT1 CUX2 DRD5 SYNE1 DNAH2 GRIA4 PNISR EEF2 MACF1 ZFR CUX1

2.30e-0514422392535575683
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

INSR IGF1R CSK EPHA2

2.46e-0525239415254900
Pubmed

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.

INSR IGF1R ROS1

2.61e-059239311094073
Pubmed

The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy.

PIK3R4 ATG16L1 DVL2

2.61e-059239325825496
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRIA4 GRIK1 GRIK2

2.61e-059239334100982
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA4 GRIK1 GRIK2

2.61e-05923939051806
Pubmed

The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.

INSR IGF1R CSK

3.71e-051023939062339
Pubmed

Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb.

MNX1 ETV4 RET

3.71e-0510239316600854
Pubmed

IRX3/5 regulate mitotic chromatid segregation and limb bud shape.

ESR1 CUX2 CUX1

3.71e-0510239332907847
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

EPPK1 GLTP FNBP1L STT3A KMT2A TIMM44 GCN1 VAT1 EPS8L2 SEC31A IDH3A EEF2 TKFC MACF1 ZFR EIF3C

3.79e-057112391633022573
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PER1 PFAS TBC1D9 KIAA2013 OSBPL8 DISP3 SYNM ZFP28 RNF213 GPAM VARS2 MACF1 UNC80

4.19e-054932391315368895
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

ACLY INSRR AP1B1 TIMM44 VAT1 SYNM BTAF1 PPP1R18 MACF1 ZFR PRKCSH

4.44e-053602391133111431
Pubmed

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer.

ERBB2 ESR1

4.70e-052239223391338
Pubmed

The Neo-Bioscore Update for Staging Breast Cancer Treated With Neoadjuvant Chemotherapy: Incorporation of Prognostic Biologic Factors Into Staging After Treatment.

ERBB2 ESR1

4.70e-052239226986538
Pubmed

The role of oestrogen receptor {alpha} in human thyroid cancer: contributions from coregulatory proteins and the tyrosine kinase receptor HER2.

ERBB2 ESR1

4.70e-052239220032008
Pubmed

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis.

INSR IGF1R

4.70e-052239224809298
Pubmed

A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.

INSR IGF1R

4.70e-052239221139139
Pubmed

The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.

INSR IGF1R

4.70e-052239225758790
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

4.70e-052239214724198
Pubmed

Evidence for muscle-dependent neuromuscular synaptic site determination in mammals.

ERBB2 MNX1

4.70e-052239218354015
Pubmed

The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.

GRIK1 GRIK2

4.70e-052239215539395
Pubmed

Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells.

SPI1 CIITA

4.70e-052239222112519
Pubmed

Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells.

INSR IGF1R

4.70e-052239227384680
Pubmed

Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.

INSR IGF1R

4.70e-052239235786404
Pubmed

Insulin-Mediated Signaling Facilitates Resistance to PDGFR Inhibition in Proneural hPDGFB-Driven Gliomas.

INSR IGF1R

4.70e-052239228138037
Pubmed

CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.

CUX2 CUX1

4.70e-052239235581205
Pubmed

IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.

ESR1 IGF1R

4.70e-052239228079144
Pubmed

Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells.

INSR IGF1R

4.70e-052239214722023
Pubmed

Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

GRIK1 GRIK2

4.70e-05223928260617
Pubmed

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.

ERBB2 EPHA2

4.70e-052239218079969
Pubmed

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation.

ERBB2 ESR1

4.70e-052239212775708
Pubmed

The Frequency and Clinical Implication of ROS1 and RET Rearrangements in Resected Stage IIIA-N2 Non-Small Cell Lung Cancer Patients.

RET ROS1

4.70e-052239225905642
Pubmed

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.

INSR IGF1R

4.70e-052239222692545
Pubmed

Complementary Value of Contralateral Parenchymal Enhancement on DCE-MRI to Prognostic Models and Molecular Assays in High-risk ER+/HER2- Breast Cancer.

ERBB2 ESR1

4.70e-052239228790119
Pubmed

ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study.

ESR1 SYNE1

4.70e-052239220056644
Pubmed

The search for BRCA1.

ETV4 VAT1

4.70e-05223927987831
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

4.70e-05223928898078
Pubmed

Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells.

ERBB2 ESR1

4.70e-052239225582774
Pubmed

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.

GRIK1 GRIK2

4.70e-052239215537878
Pubmed

The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response.

LRRK2 ATG16L1

4.70e-052239238227290
Pubmed

Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.

INSR IGF1R

4.70e-052239228065828
Pubmed

ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells.

ESR1 ETV4

4.70e-052239232046982
Pubmed

Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.

INSR IGF1R

4.70e-052239236548088
Pubmed

Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.

INSR IGF1R

4.70e-052239217189427
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

4.70e-052239214550562
Pubmed

Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ERα- breast cancer.

ERBB2 ESR1

4.70e-052239222460789
Pubmed

Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.

PAX3 PAX7

4.70e-052239221421465
Pubmed

[Effects of insulin on expression of insulin receptor and insulin-like growth factor-1 receptor and proliferation in Reh cells].

INSR IGF1R

4.70e-052239222541124
Pubmed

Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice.

INSR IGF1R

4.70e-052239219851056
InteractionGRIK5 interactions

ERBB2 GPAA1 ADCY6 GRIK1 GRIK2

2.61e-06202325int:GRIK5
InteractionVAV3 interactions

ERBB2 ESR1 INSR MAP3K1 CCNT1 IGF1R ROS1

3.10e-06552327int:VAV3
GeneFamilyReceptor Tyrosine Kinases|CD molecules

AXL INSR INSRR RET IGF1R ROS1

1.09e-06401556321
GeneFamilyFibronectin type III domain containing

AXL INSR INSRR PTPRZ1 IGF1R EPHA2 ASTN1 EGFLAM ROS1 EPHA5

1.21e-0616015510555
GeneFamilyWD repeat domain containing

WDR64 LYST PIK3R4 ATG16L1 NBEA SEC31A TEP1 PWP1 ELP2 DCAF11

8.95e-0526215510362
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

2.18e-0431552287
GeneFamilyDishevelled segment polarity proteins|PDZ domain containing

DVL2 DVL3

4.33e-0441552505
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2

7.18e-04515521199
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K20 MAP3K1 MAP3K19

1.10e-03241553654
GeneFamilyEF-hand domain containing|Plakins

EPPK1 MACF1

1.98e-0381552939
GeneFamilyCUT class homeoboxes and pseudogenes

CUX2 CUX1

2.53e-0391552527
GeneFamilyWD repeat domain containing|BEACH domain containing

LYST NBEA

2.53e-03915521230
GeneFamilyPaired boxes

PAX3 PAX7

2.53e-0391552675
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY2 ADCY6

3.14e-0310155253
GeneFamilyZinc fingers CXXC-type

KMT2A CXXC5

4.56e-03121552136
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

ERBB2 CLTCL1 MNX1 PER1 ETV4 BCR CIITA KMT2A NSD1 RNF213 RET ROS1 PAX3 PAX7

1.48e-0632323514M9150
CoexpressionGSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN

ABCA3 ESR1 INSR MAP3K20 TBC1D9 PIK3R4 PPM1L RSAD2 EPHA2 ELP2 CUX1

1.99e-0619923511M312
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 ADCY2 RYR2 RYR3 PTPRZ1 MROH2A GRIA4 GRIK2 CPS1 LRP2 ASTN1 UNC80 EPHA5

4.25e-1216023913c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 ADCY2 RYR2 RYR3 PTPRZ1 MROH2A GRIA4 GRIK2 CPS1 LRP2 ASTN1 UNC80 EPHA5

4.25e-121602391325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB RYR2 RYR3 TRANK1 DISP3 MROH2A CPS1 LRP2 ROS1 UNC80 EPHA5

5.09e-09184239112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB RYR2 RYR3 TRANK1 DISP3 MROH2A CPS1 LRP2 ROS1 UNC80 EPHA5

5.09e-09184239112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB RYR2 RYR3 TRANK1 DISP3 MROH2A CPS1 LRP2 ROS1 UNC80 EPHA5

5.09e-0918423911ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY INSRR KMT2A NSD1 NBEA SEC31A RET PAPSS2 MACF1 ZFR UNC80

9.33e-09195239113e519cffa6144a62b06124642a14c9ff39b76554
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

ERBB2 ESR1 EIF3CL TRANK1 SYNE1 RNF213 H6PD RSAD2 OVGP1 MACF1 CXCR1

1.09e-081982391176d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRK2 LYST TRANK1 PIK3CB SYNE1 FAM220A RSAD2 IGF1R LY75 EPHA5

3.34e-0817223910d354424c1f861b6607dfd63b9724f4c237b30275
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY INSRR KMT2A NBEA SEC31A RET PAPSS2 MACF1 ZFR UNC80

1.09e-07195239107796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEB ADCY2 RYR3 CUX2 SLC8A3 SLC4A10 PAX3 PAX7 CD96

3.82e-071712399b2e753e811a7639956994609f73efcdb62d04f82
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR1 FNBP1L TBC1D9 ELAC1 ARHGAP8 PLXNB1 TIRAP TTLL4 MCTP2

5.88e-071802399be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR1 FNBP1L TBC1D9 ELAC1 ARHGAP8 PLXNB1 TIRAP TTLL4 MCTP2

5.88e-0718023993b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INSRR ETV4 BDH1 MEIS2 PI4KA SIRT6 TM7SF2 MCTP2 UNC80

6.45e-0718223991923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INSRR ETV4 BDH1 MEIS2 PI4KA SIRT6 TM7SF2 MCTP2 UNC80

6.45e-07182239969ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

ABCA3 ESR1 TBC1D9 GLYR1 CXXC5 RET IGF1R SLC16A6 ELP2

8.09e-071872399a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AXL ETV4 BCR FAM162B COX4I2 GPX3 CXXC5 EGFLAM RAPGEF2

8.84e-07189239926cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DQB1 LYST MAP3K1 DNAJC10 AP1B1 CIITA EIF2AK3 KYNU CR2

1.10e-061942399ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MNX1 ACLY INSRR TRPM5 AP1B1 RET PAPSS2 IGF1R UNC80

1.15e-061952399bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

HLA-DQB1 TBC1D9 AP1B1 CIITA PI4KA FAM220A EEF2 EIF3C LY75

1.20e-06196239909d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ERBB2 EIF3CL TRANK1 SYNE1 RNF213 RSAD2 MACF1 EIF3C CXCR1

1.41e-0620023992281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 RYR3 TRANK1 MROH2A GPX3 GRIA4 LRP2 UNC80

3.77e-06169239812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A4GALT PPM1L ACCS GRIA4 ACE2 HECTD2 EGFLAM ZBTB3

4.12e-061712398b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A4GALT PPM1L ACCS GRIA4 ACE2 HECTD2 EGFLAM ZBTB3

4.12e-0617123989d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRR1 AXL COX4I2 ACE2 EPHA2 EGFLAM ENPEP

4.36e-061222397c16110934172f174f4aefe14b81abce8514b30f0
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRR1 AXL COX4I2 ACE2 EPHA2 EGFLAM ENPEP

4.36e-061222397006ac4f6807e688554d36557d29d5e5a0bc3c36f
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRR1 AXL COX4I2 ACE2 EPHA2 EGFLAM ENPEP

4.36e-061222397f3d9a5893fdee3562880fb6fc132b88169a7d997
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 MAP3K20 ADCY6 PPM1L COX4I2 PLXNB1 ASTN1 EGFLAM

4.68e-061742398197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 MAP3K20 ADCY6 PPM1L COX4I2 PLXNB1 ASTN1 EGFLAM

4.68e-0617423982eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SPI1 HLA-DQB1 FNBP1L VWDE TBC1D9 SPOCD1 TMPRSS9 TMEM63C

5.09e-061762398052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 PTPRZ1 CMAHP CUX2 GPX3 PAPSS2 ROS1 CUX1

5.31e-061772398f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AXL BCR ADCY2 FAM162B COX4I2 PLXNB1 EGFLAM ENPEP

5.53e-0617823988bae5db100f4563aa1fc7f881e7f8c59d669e37a
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AXL BCR ADCY2 FAM162B COX4I2 PLXNB1 EGFLAM ENPEP

5.53e-061782398bc0336692b84bd0fa49747ed5a031b8ed8afa0fd
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP CIITA CMAHP TUT4 CXXC5 CR2 SLC4A10 RPL17

6.26e-061812398ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GABRR1 COX4I2 MROH2A ACE2 EPHA2 ENPEP

6.50e-068523967c5ea38893372fdecf7cc3ccf46a37b4ec45f0b1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GABRR1 COX4I2 MROH2A ACE2 EPHA2 ENPEP

6.50e-068523960bfabb6761a84d6a04f9fa415106a33059d78099
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GABRR1 COX4I2 MROH2A ACE2 EPHA2 ENPEP

6.50e-068523965a2c02aeceeabd44a417b09ac8b2e2f185070b15
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

EIF3CL TRANK1 TUT4 SYNE1 RNF213 RSAD2 MACF1 EIF3C

6.78e-06183239822bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellCOVID-19_Convalescent-Myeloid-cDC|COVID-19_Convalescent / Disease group, lineage and cell class

SPI1 AXL HLA-DQB1 PER1 TBC1D9 CIITA KYNU NHSL1

7.06e-061842398ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPI1 AXL HLA-DQB1 PER1 TBC1D9 CIITA KYNU NHSL1

7.06e-061842398383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCellPBMC-Convalescent-Myeloid-cDC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPI1 AXL HLA-DQB1 PER1 TBC1D9 CIITA KYNU NHSL1

7.06e-0618423985535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPI1 AXL HLA-DQB1 PER1 TBC1D9 CIITA KYNU NHSL1

7.06e-0618423989d678b24532b7763f2e73f7ccb496259977c5204
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

FNBP1L FAM162B COX4I2 ARHGAP6 ASTN1 EGFLAM RAPGEF2 ENPEP

7.34e-061852398ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 PTPRZ1 ITGA11 CUX2 GPX3 RET PAPSS2 CUX1

7.34e-0618523985a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

SPI1 HLA-DQB1 TBC1D9 HSPA12A CIITA KYNU CXXC5 CR2

8.26e-061882398ab1384e6f71053946368502282aeebf1ba92d33e
ToppCellhealthy_donor-Lymphocytic-B_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

HLA-DQB1 TBC1D9 MAP3K1 ABCB4 DNAJC10 CIITA CXXC5 CR2

9.63e-0619223987d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

INSR SIK3 ARHGAP6 IGF1R LRP2 MACF1 RAPGEF2 CUX1

9.63e-061922398e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellhealthy_donor-Lymphocytic-B_cell-|healthy_donor / Disease condition, Lineage, Cell class and subclass

HLA-DQB1 TBC1D9 MAP3K1 ABCB4 DNAJC10 CIITA CXXC5 CR2

9.63e-061922398975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K20 PPM1L COX4I2 PLXNB1 ACE2 ASTN1 EGFLAM ENPEP

1.00e-0519323981043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY INSRR NEB TRPM5 AP1B1 SEC31A PAPSS2 UNC80

1.00e-051932398fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K20 PPM1L COX4I2 PLXNB1 ACE2 ASTN1 EGFLAM ENPEP

1.00e-0519323980266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCellCOVID-19-Myeloid-TRAM2|COVID-19 / Condition, Lineage and Cell class

VGLL3 AXL HLA-DQB1 SPOCD1 KYNU VAT1 GPX3 ARHGAP6

1.04e-051942398c5bdf2b58c10dcb09797ddaf46b2e6c80d10399f
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

AXL HLA-DQB1 LRRK2 TBC1D9 CIITA KYNU PAPSS2 NHSL1

1.04e-0519423987d682408e9a6239a4e47befc9376e760cc3d133a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR1 ADCY2 RTN2 GPX3 PAX7 STK40 CUX1 RPL17

1.12e-0519623983dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCelldistal-Epithelial-Proximal_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ETV4 ADH1C PTPRZ1 DISP3 ALOX12 LHFPL7 ACE2 ZNF425

1.12e-051962398c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCelldistal-Epithelial-Proximal_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ETV4 ADH1C PTPRZ1 DISP3 ALOX12 LHFPL7 ACE2 ZNF425

1.12e-051962398a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AXL FAM162B RYR2 COX4I2 SYNM GPX3 ARHGAP6 EGFLAM

1.16e-05197239841dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellVE-mDC2-|VE / Condition, Cell_class and T cell subcluster

SPI1 AXL HLA-DQB1 INSR TBC1D9 ABCB4 CIITA KYNU

1.16e-0519723986629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCellVE-mDC2|VE / Condition, Cell_class and T cell subcluster

SPI1 AXL HLA-DQB1 INSR TBC1D9 ABCB4 CIITA KYNU

1.16e-051972398e3172102ad17c92c3038cad37bf933eb04351048
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AXL FAM162B RYR2 COX4I2 SYNM GPX3 ARHGAP6 EGFLAM

1.16e-051972398f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

FNBP1L MEIS2 KMT2A CUX2 TUT4 ENC1 PNISR EPHA5

1.20e-051982398de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellmLN-(2)_B_cell-(22)_B_cell_memory|mLN / shred on region, Cell_type, and subtype

SPI1 HLA-DQB1 LRRK2 TBC1D9 CIITA KYNU CXXC5 CR2

1.20e-0519823984d189df1db5b41306e9653436d7d7e75ff5afa06
ToppCellmLN-B_cell-B_cell_memory|mLN / Region, Cell class and subclass

SPI1 HLA-DQB1 LRRK2 TBC1D9 CIITA KYNU CXXC5 CR2

1.20e-0519823986dc155ee487abb1319a60a7a70e84c28c9851985
ToppCellmLN-(2)_B_cell|mLN / shred on region, Cell_type, and subtype

SPI1 HLA-DQB1 TBC1D9 ABCB4 CIITA KYNU CXXC5 CR2

1.25e-0519923989464c8c72a6b2e14a27b413cc1f5d64550212776
ToppCellmLN-B_cell|mLN / Region, Cell class and subclass

SPI1 HLA-DQB1 TBC1D9 ABCB4 CIITA KYNU CXXC5 CR2

1.25e-05199239899c7d157a1e819ff86c526ffd9b7036ed3514cae
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VGLL3 MAP3K20 FAM162B COX4I2 ITGA11 GRIK1 EGFLAM ENPEP

1.25e-0519923989e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCA3 LRRK2 JOSD1 PLXNB1 VARS2 HECTD2 EPHA2 ROS1

1.29e-052002398e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

AXL FAM162B COX4I2 SYNM GPX3 ARHGAP6 EGFLAM ENPEP

1.29e-052002398c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRANK1 KMT2A SYNE1 ENC1 RNF213 RSAD2 MACF1 CD96

1.29e-052002398d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

AXL FAM162B COX4I2 SYNM GPX3 ARHGAP6 EGFLAM ENPEP

1.29e-05200239878e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SCN11A JOSD1 FAM220A ACE2 PRKCSH STK40 FITM2 ENPEP

1.29e-052002398a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AXL FAM162B COX4I2 SYNM GPX3 ARHGAP6 EGFLAM ENPEP

1.29e-05200239843b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellCOVID-19-COVID-19_Convalescent-Myeloid-cDC|COVID-19_Convalescent / Disease, condition lineage and cell class

SPI1 AXL HLA-DQB1 PER1 TBC1D9 CIITA KYNU NHSL1

1.29e-052002398ac9d7927863348a752444d2e80269a5eead943b7
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CLTCL1 NEB ADCY2 CACNG1 SYNM SLC8A3 PAX3

1.30e-051442397f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A ACLY INSRR NEB CUX2 GPX3 ACE2

3.36e-051672397b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS2 TRANK1 CIITA ITGA11 CACNG1 GRIK2 OVGP1

3.50e-051682397b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS2 TRANK1 CIITA ITGA11 CACNG1 GRIK2 OVGP1

3.50e-051682397b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellPosterior_cortex-Endothelial-MURAL|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AXL MAP3K20 A4GALT COX4I2 ACE2 EPHA2 ENPEP

3.63e-0516923970ae65daf092396b71f790b65c7a2feed90397417
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEB RYR3 CUX2 GPX3 MACF1 EGFLAM ENPEP

3.63e-05169239716c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AXL MAP3K20 A4GALT COX4I2 ACE2 EPHA2 ENPEP

3.63e-0516923978cd70ce27b1cecb83f8a376230e7ef41b079b124
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPI1 HLA-DQB1 LRRK2 CIITA CUX2 IDH3A CSK

3.63e-0516923974de0c60f3c163b7823f739ebda4e0afc68346628
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV4 PIDD1 TONSL GPX3 MACF1 EGFLAM ENPEP

3.77e-051702397e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS2 ITGA11 SYNM GRIK2 RET OR10G3 ASTN1

3.77e-051702397cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS2 ITGA11 SYNM GRIK2 RET OR10G3 ASTN1

3.77e-05170239799dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS2 ITGA11 SYNM GRIK2 RET OR10G3 ASTN1

3.77e-0517023973a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLXNB1 MAP3K19 HEATR4 C2orf81 NHSL1 EPHA2 PALM3

3.91e-0517123971854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTN2 RYR2 RYR3 GPX3 GRIA4 LRP2 RPL17

4.21e-05173239766f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTN2 RYR2 RYR3 GPX3 GRIA4 LRP2 RPL17

4.21e-051732397649b08a409095592cccf31883be69c754411280d
ToppCellTuft-tuft-4|World / Class top

FNBP1L HSPA12A SARDH SH2D7 ABTB2 RSAD2 PKD2L2

4.37e-051742397d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 FAM162B RYR3 CUX2 GPX3 PAPSS2 ROS1

4.37e-051742397ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCelldroplet-Heart-nan-24m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 PIDD1 TONSL FAM220A MYBL2

4.54e-0573239530374f4d30519ca8cd9582da1f9f906420e50244
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SCN11A COX4I2 ACE2 PKD2L2 EPHA2 ENPEP

4.65e-051202396e60b74758c8290919b326904ad841962256b72ec
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SCN11A COX4I2 ACE2 PKD2L2 EPHA2 ENPEP

4.65e-0512023963e1ae5a5422729d484a90d72f779833fe3473fa8
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SCN11A COX4I2 ACE2 PKD2L2 EPHA2 ENPEP

4.65e-05120239624d5e86931a857bb87684392172bf04294a1a46a
ToppCellmild-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

A4GALT EPS8L2 CUX2 CXXC5 IDH3A EPHA2 MYBL2

4.70e-05176239759a9c262c252b7d220a025837922d98e9d6b0a24
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PTPRZ1 TMPRSS9 SYNM ENC1 GRIK2 EGFLAM PAX3

4.87e-0517723975357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SARDH KYNU GPX3 PAPSS2 CR2 TKFC LRP2

4.87e-051772397d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY2 GPX3 H6PD GAREM2 MACF1 EGFLAM ENPEP

5.23e-051792397948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DQB1 TBC1D9 ABCB4 HSPA12A CIITA KYNU CXXC5

5.23e-051792397fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AXL BCR ADCY2 FAM162B COX4I2 PLXNB1 EGFLAM

5.23e-051792397d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AXL BCR ADCY2 FAM162B COX4I2 PLXNB1 EGFLAM

5.23e-0517923977078022e60faa86444f2a2c6eb9f767cc66b5cfa
DrugKetanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A

ESR1 KMT2A ATG16L1 ENC1 H6PD CCNT1 IGF1R ZFR DCAF11 RAPGEF2 RAI2 EPHA5

7.68e-07189238126649_DN
DrugCarbachol [51-83-2]; Down 200; 21.8uM; PC3; HT_HG-U133A

ABCA3 EPPK1 ESR1 PER1 BCR RTN2 GLYR1 KYNU H6PD CPS1 ARHGAP6 OVGP1

1.26e-06198238126742_DN
DrugBenzoates

ESR1 GRIA4 GRIK1 GRIK2

2.33e-06102384ctd:D001565
Drugmorphine hydrochloride

GABRR1 ABCA3 ACLY ESR1 INSR ADCY2 ADCY6 ABCB4 PIK3R4 AP1B1 TONSL EIF2AK3 DRD5 GRIK1 SIRT6 CR2 DMTN CXCR1

3.47e-0648123818CID000004253
DrugEN-1530

ACLY ESR1 ADCY2 ADCY6 ADH1C AP1B1 CHRNA6 DRD5 GRIA4 GRIK1 GRIK2 SIRT6 DMTN

7.97e-0627823813CID000004425
DrugNapelline [5008-52-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

PER1 KMT2A CHRNA6 CACNG1 CUX2 TEP1 ACE2 KLHL25 TTLL4 LRP2 EPHA5

8.06e-06198238114486_UP
DrugIsoniazid [54-85-3]; Down 200; 29.2uM; PC3; HT_HG-U133A

ERBB2 ABCA3 EPPK1 MNX1 F8 MAGEF1 ADCY6 SYNE1 TKFC TM7SF2 ZFR

8.45e-06199238112083_DN
Drugglutamate

GABRR1 CLTCL1 PER1 PFAS ADCY2 BDH1 ADCY6 RYR2 RYR3 TRPM5 TONSL KYNU CHRNA6 CACNG1 DRD5 GRIA4 GRIK1 GRIK2 IDH3A H6PD SIRT6 CPS1 EEF2 TKFC TTLL4 ENPEP

9.74e-0696223826CID000000611
DrugAC1L1FA8

ADCY2 ADCY6 GRIA4 GRIK1 GRIK2 ST8SIA2

1.33e-05502386CID000003150
DrugPtdIns(4)P

CLTCL1 GLTP AXL NOXA1 PIK3R4 PIK3CB PI4KA PPM1L

1.38e-051042388CID000643965
Drug4-anilinoquinazoline

ERBB2 INSR BCR RET

1.92e-05162384CID000324081
Drugmercury orange

SCN11A KYNU ENPEP

2.20e-0562383CID005359843
DrugAC1LD8Z3

ADCY2 ADCY6 TBC1D9 ABCB4 PI4KA CPS1 EEF2

3.33e-05862387CID000644309
DrugMethapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

MNX1 BCR ADCY6 SPIN1 KMT2A ENC1 CCNT1 DCAF11 RAPGEF2 EPHA5

3.47e-05191238106644_DN
Drugsecoisolariciresinol diglucoside

ERBB2 ESR1 IGF1R

3.83e-0572383ctd:C090142
DrugAC1MNCFH

INSR SYNE1 CUX1

3.83e-0572383CID003301780
DrugCyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ESR1 PIDD1 TMEM104 BCR ADCY6 DVL3 H6PD OVGP1 TTLL4 DCAF11

4.32e-05196238104834_DN
DrugLY 294002; Down 200; 0.1uM; PC3; HT_HG-U133A

PER1 PIDD1 CAMTA2 BDH1 MAGEF1 GLYR1 ABTB2 OVGP1 CSK DCAF11

4.32e-05196238101216_DN
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A

ABCA3 VGLL3 CLTCL1 ESR1 PER1 CAMTA2 ADCY6 PIK3CB GRIK2 EPHA5

4.51e-05197238104189_DN
DrugDiflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A

VGLL3 INSR PER1 NEB ADCY2 PIK3CB TUT4 SYNE1 DVL3 DCAF11

4.51e-05197238104077_UP
DrugCefixime [79350-37-1]; Down 200; 8.8uM; PC3; HT_HG-U133A

AXL MAP3K20 PIDD1 BCR RTN2 PLXNB1 DVL3 OVGP1 IGF1R ZFR

4.71e-05198238104567_DN
DrugCloperastine hydrochloride [14984-68-0]; Up 200; 11uM; HL60; HT_HG-U133A

ESR1 ADCY2 RTN2 ABCB4 GLYR1 A4GALT KYNU PAPSS2 PKD2L2 MCTP2

4.71e-05198238102549_UP
DrugFlucytosine [2022-85-7]; Up 200; 31uM; PC3; HT_HG-U133A

VGLL3 BCR HROB KYNU CHRNA6 CACNG1 TEP1 TTLL4 ASTN1 EPHA5

4.91e-05199238106690_UP
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A

EPPK1 CAMTA2 BCR LYST BDH1 TKFC IGF1R SLC25A44 ZFR DEDD

5.12e-05200238105842_DN
DiseaseMalignant neoplasm of breast

ERBB2 ABCA3 ESR1 PER1 ETV4 MAP3K1 PIK3R4 PIK3CB ACCS SPOCD1 PLXNB1 SYNE1 DVL3 PPHLN1 GRIK2 SIK3 H6PD EEF2 SLC8A3 IGF1R MACF1 ZBTB3 ENPEP CUX1

5.44e-06107423424C0006142
Diseasealcohol use disorder (implicated_via_orthology)

ERBB2 SPI1 RYR2 RYR3 PIK3CB CHRNA6 EPS8L2 DRD5 HR

2.76e-051952349DOID:1574 (implicated_via_orthology)
Diseasealcohol dependence (implicated_via_orthology)

INSR INSRR IGF1R

3.99e-0592343DOID:0050741 (implicated_via_orthology)
DiseaseIntellectual Disability

MEIS2 STT3A AP1B1 CUX2 SYNE1 NSD1 NBEA ACE2 SLC4A10 LRP2 MACF1 ASTN1 ELP2

6.52e-0544723413C3714756
Diseaseglucose metabolism disease (implicated_via_orthology)

INSR INSRR PIK3CB IGF1R

6.80e-05282344DOID:4194 (implicated_via_orthology)
Diseaseserum metabolite measurement

GPAA1 PKD1L1 ABCB4 HSPA12A A4GALT SARDH C4orf33 SPOCD1 KYNU HEATR4 GPAM ATP5MF GRIK2 CPS1 PAPSS2 GTF2H1 ELP2 PRKCSH HPS5 ENPEP

7.21e-0594523420EFO_0005653
DiseaseMalignant Neoplasms

ERBB2 ESR1 DNAJC10 GPX3 RET EPHA2 CUX1

7.56e-051282347C0006826
Diseasesleep disorder (implicated_via_orthology)

INSR INSRR IGF1R

7.75e-05112343DOID:535 (implicated_via_orthology)
Diseaseacute myeloid leukemia (implicated_via_orthology)

SPI1 KMT2A MYBL2

1.03e-04122343DOID:9119 (implicated_via_orthology)
Diseaseaspartate aminotransferase measurement

AXL HLA-DQB1 STARD10 ABCB4 HSPA12A AP1B1 CMAHP GCN1 ABTB2 VAT1 CACNG1 CUX2 DVL2 DNAH2 NSD1 RNF213 GPAM KLHL25 LY75

1.20e-0490423419EFO_0004736
DiseaseBipolar Disorder

GABRR1 ESR1 BCR ADCY2 TRANK1 ALOX12 CHRNA6 CUX2 DRD5 SYNE1 GRIK1 GRIK2 ST8SIA2

1.25e-0447723413C0005586
Diseasetaurolithocholate 3-sulfate measurement

ESR1 ADCY2 IGF1R

1.33e-04132343EFO_0021036
Diseasediabetic neuropathy (implicated_via_orthology)

INSR INSRR IGF1R

1.68e-04142343DOID:9743 (implicated_via_orthology)
DiseaseBurkitt Lymphoma

BCR A4GALT KMT2A RET

1.86e-04362344C0006413
DiseaseRHABDOMYOSARCOMA 2

PAX3 PAX7

1.87e-0432342268220
DiseaseAlveolar rhabdomyosarcoma

PAX3 PAX7

1.87e-0432342cv:C0206655
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

1.87e-0432342DOID:3529 (implicated_via_orthology)
Diseasealveolar rhabdomyosarcoma (is_implicated_in)

PAX3 PAX7

1.87e-0432342DOID:4051 (is_implicated_in)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

1.87e-0432342DOID:8545 (implicated_via_orthology)
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

HLA-DQB1 GPAM SIK3 CPS1 MACF1

1.95e-04672345EFO_0008595, EFO_0020946
Diseasebehavioural inhibitory control measurement

PRDM11 MROH2A GPAM

2.55e-04162343EFO_0008467
Diseasestomach cancer (is_implicated_in)

ERBB2 MAP3K1 GPX3 TEP1 EEF2

2.73e-04722345DOID:10534 (is_implicated_in)
DiseaseSubstance abuse problem

INSR HSPA12A SYNE1 GRIA4 GRIK2 ASTN1

3.35e-041162346C0740858
DiseaseTransitional cell carcinoma of bladder

BCR RET

3.72e-0442342C0279680
Diseasehigh grade glioma (implicated_via_orthology)

INSR INSRR PIK3CB IGF1R

4.08e-04442344DOID:3070 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

AXL INSR EPHA2 ROS1

4.45e-04452344C0278701
Diseaseprostate adenocarcinoma (is_implicated_in)

INSR PIK3CB IGF1R

5.08e-04202343DOID:2526 (is_implicated_in)
Diseasemean platelet volume

SRRM1 SPI1 STARD10 LRRK2 TRANK1 AP1B1 PIK3CB PI4KA A4GALT CMAHP THAP6 KYNU ALOX12 NT5DC4 SIK3 CPS1 DNTTIP1 LY75 CUX1

5.39e-04102023419EFO_0004584
Diseasegestational diabetes (biomarker_via_orthology)

INSR IGF1R

6.16e-0452342DOID:11714 (biomarker_via_orthology)
Disease2-hydroxy-4-(methylthio)butanoic acid measurement

GTF2H1 HPS5

6.16e-0452342EFO_0800113
DiseaseAlveolar rhabdomyosarcoma

PAX3 PAX7

6.16e-0452342C0206655
DiseaseAddison's disease (is_implicated_in)

HLA-DQB1 CIITA

6.16e-0452342DOID:13774 (is_implicated_in)
DiseaseWeaver syndrome

KMT2A NSD1

6.16e-0452342C0265210
DiseaseGlobal developmental delay

GPAA1 STT3A AP1B1 NBEA TKFC IGF1R

6.92e-041332346C0557874
Disease2-hydroxy-3-methylvalerate measurement

GTF2H1 HPS5

9.20e-0462342EFO_0800027
Diseaseserum amyloid A protein measurement

GTF2H1 HPS5

9.20e-0462342EFO_0004728
Diseasefacial morphology

SGMS1 GPAM PAX3 PAX7

9.58e-04552344EFO_0004743
DiseaseNeonatal diabetes mellitus

MNX1 INSR EIF2AK3

9.95e-04252343C0158981
DiseaseAdenocarcinoma of large intestine

ERBB2 RET ROS1 STK40 CUX1

1.02e-03962345C1319315
Diseaseneurodegenerative disease (implicated_via_orthology)

LRRK2 DVL2 DVL3 GRIA4 GRIK1 GRIK2

1.08e-031452346DOID:1289 (implicated_via_orthology)
Diseasediabetes mellitus (implicated_via_orthology)

INSR INSRR IGF1R

1.12e-03262343DOID:9351 (implicated_via_orthology)
Diseaseobesity (biomarker_via_orthology)

ALOX12 GPX3 GPAM SIRT6 CPS1 IGF1R

1.16e-031472346DOID:9970 (biomarker_via_orthology)
DiseaseX-26054 measurement

C4orf33 AKR1B15

1.28e-0372342EFO_0800939
DiseaseCongenital Pain Insensitivity

SCN11A CLTCL1

1.28e-0372342C0002768
Diseasealpha-hydroxyisovalerate measurement

GTF2H1 HPS5

1.28e-0372342EFO_0800023
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

ZMPSTE24 INSR INSRR PIK3CB IGF1R

1.52e-031052345DOID:9352 (implicated_via_orthology)
Diseaseprostate cancer (is_marker_for)

ESR1 PIK3CB KMT2A ALOX12 EEF2 IGF1R

1.58e-031562346DOID:10283 (is_marker_for)
Diseaseserum alanine aminotransferase measurement

HLA-DQB1 STARD10 PKD1L1 INSR MAP3K20 FNBP1L MAP3K1 ABCB4 TRANK1 CUX2 DVL2 DNAH2 GPAM CPS1 EPHA2 DMTN

1.66e-0386923416EFO_0004735
DiseaseX-24748 measurement

ACAD11 HEATR4

1.70e-0382342EFO_0022136
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS2 MEIS3P1

1.70e-0382342DOID:0050425 (implicated_via_orthology)
Diseaseprogeria (implicated_via_orthology)

ZMPSTE24 SIRT6

1.70e-0382342DOID:3911 (implicated_via_orthology)
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

INSR GPAM SIRT6 IGF1R

1.79e-03652344DOID:0080208 (biomarker_via_orthology)
Diseasemetabolite measurement

GABRR1 CLTCL1 GPAA1 BAAT INSR C4orf33 HEATR4 GPAM CPS1 RSAD2 HPS5 ENPEP

1.84e-0356023412EFO_0004725
DiseaseParkinson's disease (is_marker_for)

ERBB2 LRRK2 DRD5 IGF1R

2.00e-03672344DOID:14330 (is_marker_for)
Diseasefacial hair thickness measurement

SH2D7 MACF1 PAX3

2.06e-03322343EFO_0007823
DiseaseSquamous cell carcinoma of lung

IGF1R EPHA2 EPHA5

2.06e-03322343C0149782
Diseaserectum cancer (is_implicated_in)

MAP3K1 GPX3

2.17e-0392342DOID:1993 (is_implicated_in)
Diseasesusceptibility to mononucleosis measurement

ADCY2 RYR2 PRDM11 DNAH2

2.23e-03692344EFO_0008403
DiseasePrescription Drug Abuse

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C4316881
DiseaseSubstance-Related Disorders

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0236969
DiseaseOrganic Mental Disorders, Substance-Induced

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0029231
DiseaseDrug habituation

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0013170
DiseaseDrug abuse

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0013146
DiseaseDrug Use Disorders

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0013222
DiseaseDrug Dependence

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C1510472
DiseaseSubstance Dependence

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0038580
DiseaseSubstance Use Disorders

INSR HSPA12A SYNE1 GRIA4 GRIK2

2.27e-031152345C0038586
DiseaseAdenocarcinoma

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0001418
DiseaseCarcinoma, Granular Cell

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0205644
DiseaseAdenocarcinoma, Tubular

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0205645
DiseaseAdenocarcinoma, Oxyphilic

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0205642
DiseaseCarcinoma, Cribriform

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0205643
DiseaseAdenocarcinoma, Basal Cell

ERBB2 ESR1 KMT2A GPX3 EEF2

2.36e-031162345C0205641
DiseaseManic Disorder

ADCY2 TRANK1 DRD5 GRIK2

2.47e-03712344C0024713
Diseaseneuroblastoma (is_implicated_in)

NSD1 IGF1R

2.70e-03102342DOID:769 (is_implicated_in)
Diseasethrombosis (implicated_via_orthology)

PIK3CB ACE2

2.70e-03102342DOID:0060903 (implicated_via_orthology)
Diseasecup-to-disc ratio measurement, optic cup area measurement, optic disc area measurement

MAP3K20 HSPA12A

2.70e-03102342EFO_0006937, EFO_0006939, EFO_0006940
DiseaseHead and Neck Carcinoma

ERBB2 PIK3CB

2.70e-03102342C3887461
Diseaseglaucoma (is_implicated_in)

HLA-DQB1 EEF2

2.70e-03102342DOID:1686 (is_implicated_in)
Diseaserespiratory syncytial virus infectious disease (is_implicated_in)

ACE2 RSAD2

2.70e-03102342DOID:1273 (is_implicated_in)
Diseasehepatocellular carcinoma (is_marker_for)

INSR PFAS MAP3K1 SARDH GPX3 CPS1 CSK CUX1

2.91e-033012348DOID:684 (is_marker_for)
DiseaseDevelopmental delay (disorder)

STT3A TKFC IGF1R

3.14e-03372343C0424605
Diseaseamino acid measurement

CLTCL1 MEIS2 RYR2 RYR3 ACAD11 CMAHP ITGA11 GCFC2 SYNE1 GRIK2 CPS1 LRP2 MCTP2

3.15e-0367823413EFO_0005134
Diseasecocaine use

CHRNA6 GRIK1

3.29e-03112342C3496069
Diseasecryptorchidism (biomarker_via_orthology)

ESR1 IGF1R

3.29e-03112342DOID:11383 (biomarker_via_orthology)
DiseaseManic

ADCY2 TRANK1 DRD5 GRIK2

3.48e-03782344C0338831
DiseaseDepression, Bipolar

ADCY2 TRANK1 DRD5 GRIK2

3.64e-03792344C0005587
Diseasebone quantitative ultrasound measurement

ESR1 GPATCH1 MCTP2

3.65e-03392343EFO_0004514
Diseasebreast cancer (is_marker_for)

ESR1 INSR MAP3K1 ALOX12 TUT4 IGF1R

3.69e-031852346DOID:1612 (is_marker_for)
Diseaseplatelet measurement

EPPK1 HLA-DQB1 LRRK2 NT5DC4 CPS1 SLC8A3 LY75 CUX1

3.82e-033152348EFO_0005036
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

ZMPSTE24 SYNE1

3.92e-03122342DOID:11726 (implicated_via_orthology)
DiseaseHirschsprung's disease (implicated_via_orthology)

ERBB2 RET

3.92e-03122342DOID:10487 (implicated_via_orthology)
Diseaseautoimmune thyroiditis (is_implicated_in)

HLA-DQB1 LRP2

3.92e-03122342DOID:7188 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB2 ESR1 PIK3CB

4.20e-03412343C0496956
DiseaseBreast adenocarcinoma

ERBB2 ESR1 PIK3CB

4.20e-03412343C0858252
DiseaseAllodynia

SCN11A INSR ALOX12 CSK

4.53e-03842344C0458247
DiseaseMechanical Allodynia

SCN11A INSR ALOX12 CSK

4.53e-03842344C2936719
DiseaseHyperalgesia, Secondary

SCN11A INSR ALOX12 CSK

4.53e-03842344C0751212
DiseaseHyperalgesia, Primary

SCN11A INSR ALOX12 CSK

4.53e-03842344C0751211
DiseaseHyperalgesia, Thermal

SCN11A INSR ALOX12 CSK

4.53e-03842344C0751214

Protein segments in the cluster

PeptideGeneStartEntry
WMRAASLKEPGARLQ

BARGIN

376

Q6ZT62
GGKVPIKWMALESIL

ERBB2

881

P04626
DAWRELLVERLGMTP

EOLA1

51

Q8TE69
MGLFWSLKPEKLLTR

BAAT

76

Q14032
LPLSFRMSRGETKWE

C4orf33

101

Q8N1A6
VGLLQAASPSRKWML

DISP3

891

Q9P2K9
TAKDGLLLWRGDSPM

EGFLAM

871

Q63HQ2
KMIIPSLDGALFQWD

EIF2AK3

151

Q9NZJ5
PKGTFEEEMLLWRRF

ACCS

421

Q96QU6
LPVLSDASRIALMWK

A4GALT

171

Q9NPC4
IVRSSLKDPEKGMWG

BDH1

126

Q02338
LEMRKWVLSGILASE

BCR

496

P11274
MSWFSGLLVPKVDER

ADCY6

1

O43306
PSADVRTWAMAKGLV

CIITA

681

P33076
LLATGGMDRRVKLWE

ATG16L1

336

Q676U5
PMLLLTGRTWKGAIF

ADH1C

306

P00326
SRTVMGDLGWIAFPK

EPHA5

66

P54756
LGPRFMNLIKEARWD

GRIK1

356

P39086
LMPKALSTRIVGGIW

GRIK1

641

P39086
LSLEMRKDPSGAGLW

FAM220A

61

Q7Z4H9
ELLGTSDRLFWEPMK

GPX3

161

P22352
LALKVMPDSWRGLVT

ABHD16A

386

O95870
WSREELLGQLKPMFH

CAMTA2

176

O94983
PMEVLLKGALLDFLW

CMTR2

726

Q8IYT2
EAKGMGIQWRDLLSP

ABCA3

426

Q99758
KLSLMPWFHGKITRE

CSK

76

P41240
LSMKAWLGGRIRDPI

BEST1

191

O76090
PQDGFSRLKRWIMIG

AQR

1081

O60306
AVWLPAMKAKGLEIS

AP1B1

721

Q10567
SNLTSVEMLPGKRWL

CCNT1

321

O60563
MAGLKRRASQVWPEE

DEDD

1

O75618
SLKGREPFVRMQLWL

CUX2

1096

O14529
RMWLKITIPNAFIGS

DVL3

431

Q92997
IPLWAGTVIMGFRSK

MT-ATP6

106

P00846
LLKPVGEKDTWSGMR

BMS1

1116

Q14692
TAKSMLALLLGRTWP

DCUN1D5

161

Q9BTE7
DRMWLKITIPNAFLG

DVL2

441

O14641
LGEGMWLPLSKSFVI

ASTN1

546

O14525
EMAKVEGLWNLFLPA

ACAD11

426

Q709F0
FGLWRICTKRIPMDD

CACNG1

51

Q06432
AWTGRGMEFKLIEPE

ETV4

361

P43268
ALDLSMKSVPWLKAG

RAI2

316

Q9Y5P3
VLMSKRGPLAKIWLA

RAD21L1

6

Q9H4I0
DPSERAWVAGKAIVM

NSD1

371

Q96L73
REAMSKWPEGSLNGL

NOXA1

146

Q86UR1
SDLFVALLVMPWKAV

DRD5

86

P21918
ALLVMPWKAVAEVAG

DRD5

91

P21918
DMAGKLINEWSRPIF

IWS1

676

Q96ST2
ESRGMGELLPTKKFW

PUM2

11

Q8TB72
LRERWLMDGAAAVPE

PALM3

46

A6NDB9
PGMFSWEIRDRLLKD

PAX7

126

P23759
TIPKMLGTFWFTLRE

OR52E1

76

Q8NGJ3
SEGWATPLKGFMREK

PAPSS2

261

O95340
MDLDKPSVWGSLKQR

MCTP2

1

Q6DN12
EAVLWEALRKMGLRP

MAGED4

521

Q96JG8
WGPRSNLEISKMEVL

MAGEF1

241

Q9HAY2
LAGLKTMAWVPAESA

GEMIN2

6

O14893
VSTQAPDRGWMALKL

GPAA1

486

O43292
PDRGWMALKLVALIY

GPAA1

491

O43292
MCWAVEVKRPRGVSL

PRKCSH

11

P14314
GIFPKVATNIMRAWL

MEIS2

281

O14770
DQWLRASTAGMILPK

MNX1

211

P50219
DMGGLTKEWFLLLIR

HECTD2

456

Q5U5R9
ALLLAKAMGPDRAWS

HPS5

1066

Q9UPZ3
MALVPGRSKEDGLWT

LBHD1

1

Q9BQE6
SLSPWDKATLSMGRL

CUX1

596

Q13948
PSMGLTSLDVFLRWL

TMEM63C

506

Q9P1W3
GLRWKEAMLTHPLAF

HR

96

O43593
VRWMSPESLKDGVFT

IGF1R

1176

P08069
EEWAKNEGLMPRSLS

NHSL1

1481

Q5SYE7
AKLSVGFELLRKMGW

GPATCH1

151

Q9BRR8
AAPWGQGIDMERTLK

GRIA4

336

P48058
SWVRKGQLPRALDVM

PER1

1186

O15534
AMGSVKPALDWLTRE

PLXNB1

831

O43157
LVWRSMEHPGKLLFA

ESR1

391

P03372
AWRKLKLPGDSSLMT

DCAF11

416

Q8TEB1
MAAVSLRLGDLVWGK

GLYR1

1

Q49A26
WLLAGKDGVEVPFMR

PI4KA

1236

P42356
LRSFPNEMGKLSKIW

LRRK2

1281

Q5S007
SLLPDMEATLWIGLR

LY75

1001

O60449
RGPWLTMKSTLGLDE

HROB

451

Q8N3J3
EMLPSKAGIWRVECL

F8

2006

P00451
AVQSGLWPALLARMK

GCN1

681

Q92616
KLKMPEWIGGESELR

JOSD1

156

Q15040
LGWPAGVTLDMISKR

LRP2

556

P98164
KGSSILRMLEDWIKP

ENPEP

481

Q07075
PAAWVDLMIAFESRK

HSPA12A

376

O43301
MDLPRGLVVAWALSL

ITGA11

1

Q9UKX5
RWMAPESLKDGVFTT

INSR

1201

P06213
RLDFEWTLKAGALEM

ALOX12

171

P18054
LMTAKLSALLVAGAW

OR10G3

136

Q8NGC4
QGPLKSTAEDFWRMI

PTPRZ1

1801

P23471
EIEWLGFRKPSQADM

ERMN

156

Q8TAM6
ALEKVMLPTGAAFRW

CXXC5

306

Q7LFL8
RGHLVPKEMSLWESL

EPS8L2

381

Q9H6S3
MKLERAEWGNDLPSV

MACF1

601

Q9UPN3
WVAETKRKLMALGPI

MACF1

5686

Q9UPN3
IRGWKLTLVIMAISP

ABCB4

211

P21439
PGMFSWEIRDKLLKD

PAX3

126

P23760
KEAELRGSPSLAMWL

TM7SF2

211

O76062
PSVIVMADWLKIRGT

OSBPL8

146

Q9BZF1
LKKSMAWDLPSVLAG

ARHGAP6

131

O43182
MPAWIFVNRSLALGK

NT5DC4

1

Q86YG4
WDLFPEADKVRTMLV

EIF3C

766

Q99613
MSWKKALRIPGGLRA

HLA-DQB1

1

P01920
VWDLFPEADKVRTML

EIF3CL

766

B5ME19
QVLLMRWPLDKTRGT

CHRNA6

351

Q15825
VLFERPGIWKDLKTM

ADCY2

791

Q08462
TRAWASSLKMDPAGL

ATP11AUN

26

Q6ZP68
VAIKAPMFSWPRLRD

CPS1

1306

P31327
VKLGELPSWILMRDF

ATP5MF

21

P56134
DGRLVKKIWVPDMFF

GABRR1

146

P24046
MAGPAWISKVSRLLG

IDH3A

1

P50213
EEWSKAAPMLIARFG

KLHL25

366

Q9H0H3
GTIPWFMEIRLCKEI

CR2

511

P20023
KRGWSVKMGPALEDF

FNBP1L

381

Q5T0N5
TMNIFLEKVLPWLGA

BTAF1

1141

O14981
PLKLESTGLKEMPWF

GCFC2

511

P16383
WALVASMLAGSLLKE

FITM2

26

Q8N6M3
TAVGMGAKVELRWTP

EPHA2

336

P29317
ALRWTALPTPAKDML

HEATR4

411

Q86WZ0
AKWRMVLRILPHTFG

CXCR1

196

P25024
PTAWDLGKGDFRILM

ACE2

346

Q9BYF1
NMLRLGKSEPWTLAL

ACE2

556

Q9BYF1
WVSGQRKPDVTLDFM

LYST

1616

Q99698
LWEMLTREVPFKGLE

MAP3K20

196

Q9NYL2
PKVGATLALMWLKRG

GLTP

86

Q9NZD2
VRWMAPESLKDGIFT

INSRR

1156

P14616
LPWEEREKILSSMGN

KMT2A

1096

Q03164
DAWEVAKAFMPRGLA

CXorf38

111

Q8TB03
PGRLSEAEWMALTAL

C2orf81

36

A6NN90
LKAVMRRWLPAGDAL

EEF2

336

P13639
EEWSKAAPMLVARFG

ENC1

366

O14682
DSAVRLWSKKGPEVM

ELP2

136

Q6IA86
PEWKRMARTLTGLIN

DNAJC10

596

Q8IXB1
LMPKALSTRIVGGIW

GRIK2

626

Q13002
SLDALWEMPAEKRIF

ZMPSTE24

6

O75844
WEMPAEKRIFGAVLL

ZMPSTE24

11

O75844
NLRWEGVPFILMSGK

H6PD

346

O95479
IPDFAWKVSAVMLLG

LHFPL7

61

Q6ICI0
AMSPEEFGKLALWKR

DMTN

381

Q08495
MILRGNEPTWAEAKR

DNAH2

3131

Q9P225
PDHWIKRGTALLMSL

DNAH2

4411

Q9P225
ERLSQMPAWKRGLLE

PPP1R18

31

Q6NYC8
DEGAWMKRLAVFSQP

RYR2

3291

Q92736
VLMIDWPKALLGRAV

PKD1L1

1126

Q8TDX9
RTTGAPDITWGMLKK

PPHLN1

401

Q8NEY8
MLPRAAWSLVLRKGG

COX4I2

1

Q96KJ9
NLVLRWRGSTPKEMG

MAP3K19

1001

Q56UN5
ILLWTGRFKSMEEIP

FAM162B

76

Q5T6X4
QRKGADALWMATLPI

PIDD1

741

Q9HB75
WRKLGAPSEKLIMGI

OVGP1

246

Q12889
GIFPKVATNIMRAWL

MEIS3P1

166

A6NDR6
FAPAIMALKERIGWR

SLC16A6

166

O15403
KADIWRLAAVDPLMT

MROH2A

1211

A6NES4
FQLEPSDPMLWRKTL

MAP3K1

366

Q13233
RRKPTMTLEEGLWQA

NUTM2F

246

A1L443
LRWSMGAFPLDLIVS

GAREM2

11

Q75VX8
VEPRLLGTAMEWLKT

RTN2

266

O75298
SVPLLILWRDKIGVM

TAS2R38

266

P59533
EWARGKTLPTGDRIM

TAS2R40

46

P59535
KIMSVLSEWGLFRGL

VARS2

441

Q5ST30
RKSILALVDGQPWDM

MRPL39

101

Q9NYK5
RGKPSDMWALGVVLF

STK40

251

Q8N2I9
KNRDVITLRSWLPMG

STARD10

126

Q9Y365
MWVLTPAAFAGKLLS

RSAD2

1

Q8WXG1
PRKLLSSDLFEEWMG

TAGAP

166

Q8N103
KWLLQMSGRLVAPDL

SYNE1

3936

Q8NF91
MLSWRLQTGPEKAEL

SYNM

1

O15061
RWAEIAKMLPGRTDN

MYBL2

156

P10244
LGERAAKWRTPDGLM

PELI3

216

Q8N2H9
KLLFSMLRGESGIWP

NBEA

196

Q8NFP9
VSPAMIRLTGWVLLK

GPAM

181

Q9HCL2
FSDPAGKLVWMRLLS

PRDM11

486

Q9NQV5
AMWKGVLRPGTALVL

EPPK1

4916

P58107
KLQPEFMILASDGLW

PPM1L

291

Q5SGD2
LLMLTGKISPWTGRF

STT3A

316

P46977
SILWIPAFMARGGKE

ST8SIA2

236

Q92186
WMKLGDADPNFDRLI

SIK3

316

Q9Y2K2
LREALGWPRLTAVMK

OR6T1

301

Q8NGN1
GRWPKKSAEFLLHML

RPL17

81

P18621
PWGLMKGLSARIISA

SLC25A44

271

Q96H78
LLDLLRSGDMKDSIW

SPI1

176

P17947
LWKEAGLDLRMLPYG

PIK3CB

826

P42338
AMKRLDVNAAGIWEP

THAP6

41

Q8TBB0
WTMEERGLAPKFDTT

SIRT6

71

Q8N6T7
LSRWTPFIKDIMEDA

STXBP3

471

O00186
EDKVPMFGLEAIWRN

SARDH

831

Q9UL12
DITMELRALGVPWKL

ABTB2

731

Q8N961
LTLLNPKGRIWTMVA

ACLY

266

P53396
AKMPIVGLGTWRSLL

AKR1B15

11

C9JRZ8
KLGDKRMVFDPWLIG

CMAHP

46

Q9Y471
TPDWIFLLRGVMKIS

CLTCL1

511

P53675
LLTAGSDMKIRFWDL

PIK3R4

1256

Q99570
LSSPMEVGKKLLEWF

RAPGEF2

306

Q9Y4G8
VILWDMSLGKPAASL

PWP1

281

Q13610
SLLGDMEWRLTKEEP

RNF213

956

Q63HN8
TERDPVLWSLMLAIG

RNF213

2676

Q63HN8
NEWRILPGKSMSDTL

VWDE

596

Q8N2E2
LMAERIAWAPEGKDR

GTF2H1

26

P32780
PWMVKRELTGSLFSG

ZFP28

286

Q8NHY6
PVCGKRFWEAALLMR

ZNF865

851

P0CJ78
GALPAWAMELLVEKA

ZFR2

806

Q9UPR6
KEMALRKVGGLALWD

UNC80

2821

Q8N2C7
KDGMSWPVIVAALLF

CD96

516

P40200
DVKLWERPSMQLLGL

TEP1

2576

Q99973
LVGEEQPFAMKSWLR

TRPM5

71

Q9NZQ8
LSSDRAAAGMVWKPK

DNTTIP1

176

Q9H147
PARESLKTMLAVGWT

RYR3

2671

Q15413
GSKDEWRGMVLARAP

SPIN1

146

Q9Y657
LAGDWLELDMPLTRS

TONSL

831

Q96HA7
PWEGVLDMFSIKRFR

SPOCD1

866

Q6ZMY3
KNAREFMGELWPLLL

SRRM1

96

Q8IYB3
LPSAEETKKLMWLFG

PFAS

51

O15067
MSVAFVPDWLRGKAE

SS18L2

1

Q9UHA2
LFTKRELSWLDDLMP

SLC4A10

1026

Q6U841
LVLKGIPESMRGELW

TBC1D9

511

Q6ZT07
LTMPKAFATAGWLVS

TMEM104

31

Q8NE00
GRIAKMPVKWIAIES

AXL

706

P30530
RLKGWILEIMSSQPL

TMPRSS9

726

Q7Z410
MWLRSVLGLPEKETI

MYCBPAP

786

Q8TBZ2
PKLFGDWEAQLRRIM

SGMS1

246

Q86VZ5
MGSLGATWRQEFPKL

SH2D7

321

A6NKC9
WRVITVPAMLAGKTL

ROS1

1371

P08922
PVGLRDFIWRTMELS

ELAC1

96

Q9H777
IRSITDFWKFMEGPL

PKD2L2

81

Q9NZM6
SWGSVRPLMKLLEIS

PLPP6

126

Q8IY26
GRIPVKWMAIESLFD

RET

911

P07949
DGDLTMWPRLVSNSK

ARHGAP8

101

P85298
KPLGKMADWFRQTLL

TIRAP

16

P58753
GDPDKVLRMLYVWAL

TIMM44

411

O43615
LTGPKRNLMALARTW

VAT1

291

Q99536
DFPSWAMELLVEKAI

ZFR

941

Q96KR1
TLPAWIREGLEKMER

PNISR

231

Q8TF01
AGWDSLLSPMLRSKE

SCN11A

1551

Q9UI33
KGARMLWELAIDFSP

TRANK1

851

O15050
AISKSKMGLTPLWRD

VGLL3

121

A8MV65
KMGLTPLWRDSSALS

VGLL3

126

A8MV65
RGILAIAWSMADPEL

SEC31A

261

O94979
GKAAPGDRTMLDSLW

TKFC

486

Q3LXA3
LLGSWIEGFDPKRMD

TUT4

541

Q5TAX3
GFDIMLDENLKPWVL

TTLL4

891

Q14679
AFSKPDLITWMEQGR

ZNF425

51

Q6IV72
LWTLEGRLLKDMLPF

WDR64

796

B1ANS9
MLREFSKWGVEASPG

ZBTB3

1

Q9H5J0
FSLKLNQWRLGEPML

KLHL38

356

Q2WGJ6
LLWAQLFSPGVEMKK

KIAA2013

336

Q8IYS2
KRPWITGDESIVGLM

KYNU

106

Q16719
IALGEPKWMERGISA

SLC8A3

616

P57103
PKWMERGISALLLSP

SLC8A3

621

P57103
WVPFGSLEMEKAKRA

NEB

961

P20929