Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	2.07e-08	5	162	4	GO:0030156
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	NES KRT31 KRT32 KRT33A KRT33B EVPL KRT25 PRPH	9.88e-07	99	159	8	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	NES KRT31 KRT32 KRT33A KRT33B EVPL KRT25 PRPH	1.07e-06	100	159	8	GO:0045103
GeneOntologyBiologicalProcess	rRNA catabolic process	ERN2 SLFN13 DEDD2 EXOSC4	4.34e-06	15	159	4	GO:0016075
GeneOntologyBiologicalProcess	protein localization to M-band	ANK2 OBSCN	5.91e-05	2	159	2	GO:0036309
GeneOntologyCellularComponent	supramolecular fiber	TLK2 NES ANK2 VMAC KRT31 KRT32 KRT33A KRT33B SPTBN1 OBSCN CKAP5 EVPL CORO1B JPH1 SPTBN4 ARHGAP4 GAS2L1 MYH14 RASSF1 DLG1 MYH15 TEKT4 GOLGA8A KRT25 PBXIP1 TBCD PRPH	3.87e-07	1179	162	27	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	TLK2 NES ANK2 VMAC KRT31 KRT32 KRT33A KRT33B SPTBN1 OBSCN CKAP5 EVPL CORO1B JPH1 SPTBN4 ARHGAP4 GAS2L1 MYH14 RASSF1 DLG1 MYH15 TEKT4 GOLGA8A KRT25 PBXIP1 TBCD PRPH	4.42e-07	1187	162	27	GO:0099081
GeneOntologyCellularComponent	main axon	MYOC SPTBN1 BCAN SPTBN4 DLG1 DLG2 PARD3	5.96e-06	89	162	7	GO:0044304
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	TLK2 NES VMAC KRT31 KRT32 KRT33A KRT33B CKAP5 EVPL CORO1B SPTBN4 ARHGAP4 GAS2L1 RASSF1 DLG1 TEKT4 GOLGA8A KRT25 PBXIP1 TBCD PRPH	6.48e-06	899	162	21	GO:0099513
GeneOntologyCellularComponent	intermediate filament	TLK2 NES VMAC KRT31 KRT32 KRT33A KRT33B EVPL KRT25 PRPH	1.15e-05	227	162	10	GO:0005882
GeneOntologyCellularComponent	node of Ranvier	MYOC BCAN SPTBN4 DLG1	1.53e-05	20	162	4	GO:0033268
GeneOntologyCellularComponent	intermediate filament cytoskeleton	TLK2 NES VMAC KRT31 KRT32 KRT33A KRT33B EVPL KRT25 PRPH	4.05e-05	263	162	10	GO:0045111
GeneOntologyCellularComponent	axon	CNTNAP3B ATP7A TSPOAP1 MYOC SPTBN1 BCAN GRM3 PTK7 SPTBN4 ARHGAP4 KIRREL3 MYH14 DLG1 DLG2 BLOC1S3 TNFRSF1A PARD3 RTN4RL2 PRPH	6.35e-05	891	162	19	GO:0030424
GeneOntologyCellularComponent	type III intermediate filament	VMAC PRPH	8.77e-04	6	162	2	GO:0045098
GeneOntologyCellularComponent	myosin filament	OBSCN MYH14 MYH15	9.27e-04	25	162	3	GO:0032982
GeneOntologyCellularComponent	lateral loop	DLG1 PARD3	1.22e-03	7	162	2	GO:0043219
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	1.30e-03	28	162	3	GO:0002177
GeneOntologyCellularComponent	axon initial segment	BCAN SPTBN4 DLG2	1.44e-03	29	162	3	GO:0043194
Domain	SH3_2	TSPOAP1 RIMBP3 CASKIN1 MAP3K10 DLG1 DLG2 RIMBP3C RIMBP3B	4.96e-07	86	152	8	PF07653
Domain	SH3_2	TSPOAP1 RIMBP3 CASKIN1 MAP3K10 DLG1 DLG2 RIMBP3C RIMBP3B	4.96e-07	86	152	8	IPR011511
Domain	Keratin_I	KRT31 KRT32 KRT33A KRT33B KRT25 PRPH	1.44e-06	44	152	6	IPR002957
Domain	Filament	NES KRT31 KRT32 KRT33A KRT33B KRT25 PRPH	1.77e-06	71	152	7	SM01391
Domain	IF	NES KRT31 KRT32 KRT33A KRT33B KRT25 PRPH	1.95e-06	72	152	7	PS00226
Domain	Filament	NES KRT31 KRT32 KRT33A KRT33B KRT25 PRPH	2.14e-06	73	152	7	PF00038
Domain	IF	NES KRT31 KRT32 KRT33A KRT33B KRT25 PRPH	2.81e-06	76	152	7	IPR001664
Domain	ANK_REPEAT	ANKFY1 ANK2 MIB2 CAMTA2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	7.31e-06	253	152	11	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKFY1 ANK2 MIB2 CAMTA2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	7.59e-06	254	152	11	IPR020683
Domain	ANK_REP_REGION	ANKFY1 ANK2 MIB2 CAMTA2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	7.59e-06	254	152	11	PS50297
Domain	Ankyrin_rpt	ANKFY1 ANK2 MIB2 CAMTA2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	1.02e-05	262	152	11	IPR002110
Domain	SH3	TSPOAP1 OBSCN RIMBP3 ARHGAP4 CASKIN1 MAP3K10 DLG1 DLG2 RIMBP3C RIMBP3B	1.12e-05	216	152	10	SM00326
Domain	SH3	TSPOAP1 OBSCN RIMBP3 ARHGAP4 CASKIN1 MAP3K10 DLG1 DLG2 RIMBP3C RIMBP3B	1.12e-05	216	152	10	PS50002
Domain	Intermediate_filament_CS	NES KRT31 KRT32 KRT33A KRT33B PRPH	1.22e-05	63	152	6	IPR018039
Domain	SH3_domain	TSPOAP1 OBSCN RIMBP3 ARHGAP4 CASKIN1 MAP3K10 DLG1 DLG2 RIMBP3C RIMBP3B	1.31e-05	220	152	10	IPR001452
Domain	Death_domain	TNFRSF25 ANK2 IRAK1 TNFRSF10D TNFRSF1A	1.35e-05	38	152	5	IPR000488
Domain	Ank	ANKFY1 ANK2 MIB2 CAMTA2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	1.79e-05	228	152	10	PF00023
Domain	-	ANKFY1 ANK2 MIB2 CAMTA2 POTEB2 ASB18 CASKIN1 KANK3 TONSL NOTCH3	3.66e-05	248	152	10	1.25.40.20
Domain	ANK	ANKFY1 ANK2 MIB2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	4.06e-05	251	152	10	SM00248
Domain	Ank_2	ANKFY1 ANK2 MIB2 POTEB2 ASB18 CASKIN1 KANK3 TONSL NOTCH3	6.79e-05	215	152	9	PF12796
Domain	-	TNFRSF25 ANK2 IRAK1 CARD9 DEDD2 TNFRSF1A	1.12e-04	93	152	6	1.10.533.10
Domain	Death	TNFRSF25 ANK2 IRAK1 TNFRSF1A	1.44e-04	33	152	4	PF00531
Domain	DEATH-like_dom	TNFRSF25 ANK2 IRAK1 CARD9 DEDD2 TNFRSF1A	1.58e-04	99	152	6	IPR011029
Domain	DEATH_DOMAIN	TNFRSF25 ANK2 TNFRSF10D TNFRSF1A	2.51e-04	38	152	4	PS50017
Domain	MAGUK_N_PEST	DLG1 DLG2	3.91e-04	4	152	2	PF10608
Domain	PDZ_assoc	DLG1 DLG2	3.91e-04	4	152	2	PF10600
Domain	DLG1_PEST_dom	DLG1 DLG2	3.91e-04	4	152	2	IPR019590
Domain	PDZ_assoc	DLG1 DLG2	3.91e-04	4	152	2	IPR019583
Domain	Spectrin_bsu	SPTBN1 SPTBN4	3.91e-04	4	152	2	IPR016343
Domain	MAGUK_N_PEST	DLG1 DLG2	3.91e-04	4	152	2	SM01277
Domain	DLG1	DLG1 DLG2	3.91e-04	4	152	2	IPR016313
Domain	Myosin_tail_1	MYH14 MYH15 CCDC102A	3.94e-04	18	152	3	PF01576
Domain	Myosin_tail	MYH14 MYH15 CCDC102A	3.94e-04	18	152	3	IPR002928
Domain	SH3_9	TSPOAP1 RIMBP3 MAP3K10 RIMBP3C RIMBP3B	4.38e-04	78	152	5	PF14604
Domain	HEAT	HEATR4 CKAP5 NCAPD2 TBCD	6.21e-04	48	152	4	PF02985
Domain	TNFR_c6	TNFRSF25 TNFRSF10D TNFRSF1A	7.26e-04	22	152	3	PF00020
Domain	PUB_domain	RNF31 ERN2	9.66e-04	6	152	2	IPR018997
Domain	TNFR	TNFRSF25 TNFRSF10D TNFRSF1A	1.20e-03	26	152	3	SM00208
Domain	HEAT	HEATR4 CKAP5 NCAPD2 TBCD	1.27e-03	58	152	4	IPR000357
Domain	DEATH	TNFRSF25 ANK2 TNFRSF1A	1.34e-03	27	152	3	SM00005
Domain	CBM21_dom	PPP1R3E PPP1R3G	1.35e-03	7	152	2	IPR005036
Domain	CBM21	PPP1R3E PPP1R3G	1.35e-03	7	152	2	PS51159
Domain	CBM_21	PPP1R3E PPP1R3G	1.35e-03	7	152	2	PF03370
Domain	TNFR_NGFR_1	TNFRSF25 TNFRSF10D TNFRSF1A	1.65e-03	29	152	3	PS00652
Domain	TNFR_NGFR_2	TNFRSF25 TNFRSF10D TNFRSF1A	1.65e-03	29	152	3	PS50050
Domain	Spectrin_repeat	SPTBN1 EVPL SPTBN4	1.65e-03	29	152	3	IPR002017
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	2.37e-09	5	164	4	17855024
Pubmed	Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.	KRT31 KRT32 KRT33A KRT33B	7.10e-09	6	164	4	10559501
Pubmed	Human hair keratins.	KRT31 KRT32 KRT33A KRT33B	5.90e-08	9	164	4	7686952
Pubmed	The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.	KRT31 KRT32 KRT33A KRT33B	9.79e-08	10	164	4	10391933
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TLK2 NES ANKFY1 ANK2 NOP56 SPTBN1 CKAP5 NCL CORO1B SEC31A GRM3 CDC42BPB SPTBN4 UBR5 CASKIN1 DLG1 DLG2 PARD3 GOLGA8A	1.64e-07	963	164	19	28671696
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	4.10e-07	4	164	3	19091768
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 ANKFY1 ANK2 SPTBN1 OBSCN SEC31A CDC42BPB JPH1 GPC3 MYH14 PARD3 WIPF2 NOTCH3	7.66e-07	497	164	13	23414517
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 OBSCN IRAK1 MIB2 CORO1B TEP1 CDC42BPB CCDC142 GAS2L1 TLK1 PROM2 CASKIN1 KANK3 NCAPD2 TP53I13 SAC3D1 KAZALD1 ABCD1 TBCD	1.29e-06	1105	164	19	35748872
Pubmed	A proteome-scale map of the SARS-CoV-2-human contactome.	KRT31 KRT32 LAP3 CARD9 TEKT4 PBXIP1 ABHD16A PRPH	1.80e-06	173	164	8	36217029
Pubmed	ELF a beta-spectrin is a neuronal precursor cell marker in developing mammalian brain; structure and organization of the elf/beta-G spectrin gene.	NES ANK2 SPTBN1	2.04e-06	6	164	3	12149647
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	NOP56 SPTBN1 CKAP5 IRAK1 EVPL CORO1B UNC45A PROM2 DLG1 PLCB3 PARD3 WIPF2 NOTCH3	3.14e-06	565	164	13	25468996
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NES ANKFY1 RNF31 NOP56 PLEKHG4 SPTBN1 LARS1 CKAP5 SHMT2 NCL CORO1B SEC31A UNC45A UBR5 MYH14 BAZ1A NCAPD2 CCT6B PARD3 DDX24	6.50e-06	1353	164	20	29467282
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	WFS1 MIB2 CDC42BPB UBR5 ACAN CASKIN1 DLG1 DLG2 PARD3 PBXIP1 PRPH	6.87e-06	430	164	11	32581705
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATP7A ANK2 NOP56 SPTBN1 LARS1 CKAP5 IRAK1 CORO1B SEC31A UNC45A JPH1 NCAPD2 DLG1 PARD3	7.37e-06	708	164	14	39231216
Pubmed	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.	KRT31 KRT33A KRT33B	8.47e-06	9	164	3	9756910
Pubmed	New consensus nomenclature for mammalian keratins.	KRT31 KRT32 KRT33A KRT33B KRT25	1.24e-05	63	164	5	16831889
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 ANK2 NOP56 KRT31 KRT33A KRT33B SPTBN1 NCL PTK7 SPTBN4 TLK1 MYH14 BAZ1A NCAPD2 DLG1 DLG2 MYH15 CFAP74 ATP11A PRPH	1.64e-05	1442	164	20	35575683
Pubmed	A role for FE65 in controlling GnRH-1 neurogenesis.	NES NOTCH3 PRPH	1.65e-05	11	164	3	21228158
Pubmed	The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.	KRT33A KRT33B KRT25	2.20e-05	12	164	3	15617563
Pubmed	The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.	TLK2 TLK1	2.21e-05	2	164	2	21647934
Pubmed	Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis.	NCL TERT	2.21e-05	2	164	2	23076205
Pubmed	Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial-mesenchymal transition in lung endothelial cells.	NES NOTCH3	2.21e-05	2	164	2	37735673
Pubmed	Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility.	TEP1 TERT	2.21e-05	2	164	2	24269974
Pubmed	Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.	TLK2 TLK1	2.21e-05	2	164	2	32755577
Pubmed	cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.	TLK2 TLK1	2.21e-05	2	164	2	9427565
Pubmed	Nucleolin interacts with telomerase.	NCL TERT	2.21e-05	2	164	2	15371412
Pubmed	Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.	NES ADGRB1	2.21e-05	2	164	2	25376607
Pubmed	Identification of hallmarks of lung adenocarcinoma prognosis using whole genome sequencing.	TERT PBXIP1	2.21e-05	2	164	2	26497366
Pubmed	βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport.	ANK2 SPTBN1	2.21e-05	2	164	2	31209033
Pubmed	Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.	ANK2 SPTBN1	2.21e-05	2	164	2	15262991
Pubmed	Human telomerase contains evolutionarily conserved catalytic and structural subunits.	TEP1 TERT	2.21e-05	2	164	2	9389643
Pubmed	Differential expression of type I hair keratins.	KRT33A KRT33B	2.21e-05	2	164	2	1689759
Pubmed	Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding.	TEP1 TERT	2.21e-05	2	164	2	11029039
Pubmed	RASSF1A and SOCS1 genes methylation status as a noninvasive marker for hepatocellular carcinoma.	RASSF1 SOCS1	2.21e-05	2	164	2	30689554
Pubmed	Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma.	TEP1 TERT	2.21e-05	2	164	2	14606063
Pubmed	Association of a Single Nucleotide Variant in TERT with Airway Disease in Japanese Rheumatoid Arthritis Patients.	TERT ATP11A	2.21e-05	2	164	2	38003027
Pubmed	Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma.	NCL TERT	2.21e-05	2	164	2	18701711
Pubmed	A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms.	KRT33A KRT33B	2.21e-05	2	164	2	7565656
Pubmed	Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.	ANK2 SPTBN1	2.21e-05	2	164	2	25632041
Pubmed	The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer.	STAT4 SOCS1	2.21e-05	2	164	2	38774752
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ANK2 SPTBN1 GRM3 SPTBN4 UBR5 CASKIN1 DLG1 DLG2	2.73e-05	251	164	8	27507650
Pubmed	Sequence and expression of murine type I hair keratins mHa2 and mHa3.	KRT32 KRT33A KRT33B	3.61e-05	14	164	3	7514534
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	3.61e-05	14	164	3	17662146
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TNFRSF25 ABCA2 ANK2 SPTBN1 LARS1 CKAP5 SEC31A CDC42BPB JPH1 SPTBN4 TARS3 NAA25 MYH14 USP32 MAP3K10 DLG1 DLG2 PBXIP1	3.92e-05	1285	164	18	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	NES ANK2 WFS1 SPTBN1 LARS1 CKAP5 NCL BCAN CORO1B GRM3 CDC42BPB SPTBN4 GAS2L1 TARS3 MYH14 CASKIN1 DLG1 DLG2 PBXIP1	4.86e-05	1431	164	19	37142655
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	ANK2 SPTBN1 SPTBN4	5.51e-05	16	164	3	21745462
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TLK2 NOP56 SPTBN1 CYP27B1 OBSCN SHMT2 UNC13D CAMTA2 SEC31A CUBN BAZ1A RASSF1 EXOC3L4 DLG1 ATP11A PARD3	5.87e-05	1084	164	16	11544199
Pubmed	A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.	SPTBN1 SPTBN4	6.61e-05	3	164	2	11294830
Pubmed	Heterogeneity in the phosphorylation of human death receptors by p42(mapk/erk2).	TNFRSF25 TNFRSF1A	6.61e-05	3	164	2	11606045
Pubmed	Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.	TLK2 TLK1	6.61e-05	3	164	2	28535374
Pubmed	A death-domain-containing receptor that mediates apoptosis.	TNFRSF25 TNFRSF1A	6.61e-05	3	164	2	8934525
Pubmed	Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.	CD6 TNFRSF1A	6.61e-05	3	164	2	20430450
Pubmed	Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines.	TERT TG	6.61e-05	3	164	2	17671725
Pubmed	Associations of CD6, TNFRSF1A and IRF8 polymorphisms with risk of inflammatory demyelinating diseases.	CD6 TNFRSF1A	6.61e-05	3	164	2	22994200
Pubmed	Vitamin D mediates the relationship between placental cathelicidin and group B streptococcus colonization during pregnancy.	CYP27B1 CUBN	6.61e-05	3	164	2	28622535
Pubmed	Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma.	TEP1 TERT	6.61e-05	3	164	2	12918126
Pubmed	Expression of mKirre, a mammalian homolog of Drosophila kirre, in the developing and adult mouse brain.	NES KIRREL3	6.61e-05	3	164	2	15908127
Pubmed	The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study.	CD6 TNFRSF1A	6.61e-05	3	164	2	21552549
Pubmed	Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.	ANK2 OBSCN	6.61e-05	3	164	2	18782775
Pubmed	Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.	STAT4 SOCS1	6.61e-05	3	164	2	12221108
Pubmed	Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells.	TEP1 TERT	6.61e-05	3	164	2	11942411
Pubmed	β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.	SPTBN1 SPTBN4	6.61e-05	3	164	2	32425157
Pubmed	SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit.	DLG1 DLG2	6.61e-05	3	164	2	9677374
Pubmed	Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.	CARD9 TRIM62	6.61e-05	3	164	2	29073062
Pubmed	The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.	RNF31 TNFRSF1A	6.61e-05	3	164	2	28120397
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK2 OBSCN	6.61e-05	3	164	2	12527750
Pubmed	MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Ménétrier-like gastropathy.	MIB2 NOTCH3	6.61e-05	3	164	2	28013292
Pubmed	Investigation of the relationship between CTLA4 and the tumor suppressor RASSF1A and the possible mediating role of STAT4 in a cohort of Egyptian patients infected with hepatitis C virus with and without hepatocellular carcinoma.	STAT4 RASSF1	6.61e-05	3	164	2	33796885
Pubmed	The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.	TLK2 TLK1	6.61e-05	3	164	2	38498025
Pubmed	Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells.	CARD9 TRIM62	6.61e-05	3	164	2	27779380
Pubmed	Requirement of neurotrophin-3 for the survival of proliferating trigeminal ganglion progenitor cells.	NES PRPH	6.61e-05	3	164	2	8756286
Pubmed	The establishment of telomerase-immortalized Tangier disease cell lines indicates the existence of an apolipoprotein A-I-inducible but ABCA1-independent cholesterol efflux pathway.	TERT ABCD1	6.61e-05	3	164	2	15001567
Pubmed	The RAIG family member, GPRC5D, is associated with hard-keratinized structures.	KRT33A KRT33B	6.61e-05	3	164	2	15086536
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	TLK2 NOP56 KRT31 KRT32 KRT33A KRT33B LARS1 SHMT2 TNFRSF10D UNC45A CDC42BPB TLK1 NAA25 UBR5 TONSL PARD3 DDX24	1.28e-04	1284	164	17	17353931
Pubmed	BAC contig from a 3-cM region of mouse chromosome 11 surrounding Brca1.	KRT32 KRT33A KRT33B	1.29e-04	21	164	3	11013085
Pubmed	IL-12 protects against coxsackievirus B3-induced myocarditis by increasing IFN-gamma and macrophage and neutrophil populations in the heart.	STAT4 TNFRSF1A	1.32e-04	4	164	2	15611248
Pubmed	Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication.	TLK2 TLK1	1.32e-04	4	164	2	10523312
Pubmed	Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma.	STAT4 TNFRSF1A	1.32e-04	4	164	2	17404323
Pubmed	Telomerase is controlled by protein kinase Calpha in human breast cancer cells.	TEP1 TERT	1.32e-04	4	164	2	9837921
Pubmed	G-protein-activated phospholipase C-beta, new partners for cell polarity proteins Par3 and Par6.	PLCB3 PARD3	1.32e-04	4	164	2	15782111
Pubmed	Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family.	MYH14 MYH15	1.32e-04	4	164	2	11919279
Pubmed	Transient membrane recruitment of IRAK-1 in response to LPS and IL-1beta requires TNF R1.	IRAK1 TNFRSF1A	1.32e-04	4	164	2	18562480
Pubmed	Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.	ANK2 SPTBN1	1.32e-04	4	164	2	34812142
Pubmed	SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma.	SPTBN1 SOCS1	1.32e-04	4	164	2	33754058
Pubmed	Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis.	TEP1 TERT	1.32e-04	4	164	2	18938767
Pubmed	USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling.	CARD9 TRIM62	1.32e-04	4	164	2	33093067
Pubmed	H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1.	STAT4 SOCS1	1.32e-04	4	164	2	27050510
Pubmed	Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.	RNF31 IRAK1	1.32e-04	4	164	2	24491438
Pubmed	Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.	CARD9 TRIM62	1.32e-04	4	164	2	26488816
Pubmed	Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.	TNFRSF25 TNFRSF1A	1.32e-04	4	164	2	9915703
Pubmed	Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.	TLK2 TLK1	1.32e-04	4	164	2	11470414
Pubmed	Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.	ANK2 SPTBN1	1.32e-04	4	164	2	21186323
Pubmed	Association of multiple sclerosis susceptibility variants and early attack location in the CNS.	CD6 TNFRSF1A	1.32e-04	4	164	2	24130718
Pubmed	Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.	DLG1 DLG2	1.32e-04	4	164	2	21031555
Pubmed	Evaluation of MYOC, ACAN, HGF, and MET as candidate genes for high myopia in a Han Chinese population.	MYOC ACAN	1.32e-04	4	164	2	24766640
Pubmed	Synaptic scaffold evolution generated components of vertebrate cognitive complexity.	DLG1 DLG2	1.32e-04	4	164	2	23201973
Pubmed	Neuronal and glial properties coexist in a novel mouse CNS immortalized cell line.	NES PRPH	1.32e-04	4	164	2	10527628
Pubmed	RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1).	RASSF1 TNFRSF1A	1.32e-04	4	164	2	29470995
Pubmed	Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development.	NES NOTCH3	1.32e-04	4	164	2	8951795
Pubmed	Lecticans: organizers of the brain extracellular matrix.	BCAN ACAN	1.32e-04	4	164	2	10766023
Interaction	KRT75 interactions	PLEKHG4 KRT31 KRT32 KRT33B CARD9 TEKT4 DDX24 KRT25 C19orf25 PRPH	2.24e-06	181	163	10	int:KRT75
Cytoband	17q21.2	KRT32 KRT33B WIPF2 KRT25	1.20e-04	70	164	4	17q21.2
GeneFamily	Keratins, type I	KRT31 KRT32 KRT33A KRT33B KRT25	6.99e-07	28	111	5	608
GeneFamily	Ankyrin repeat domain containing	ANKFY1 ANK2 MIB2 POTEB2 ASB18 CASKIN1 KANK3 TONSL POTEB NOTCH3	2.42e-06	242	111	10	403
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	BCAN ACAN	2.22e-04	4	111	2	574
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN SIGLEC16 PTK7 KIRREL3 PXDNL KAZALD1	4.76e-04	161	111	6	593
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF25 TNFRSF10D TNFRSF1A	7.33e-04	29	111	3	782
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN1 SPTBN4	7.69e-04	7	111	2	1113
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEB2 POTEB	2.79e-03	13	111	2	685
GeneFamily	Myosin heavy chains	MYH14 MYH15	3.72e-03	15	111	2	1098
ToppCell	droplet-Tongue-nan-24m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICDL2 ABCA2 KRT31 KRT33A KRT33B NIBAN3 GPATCH11	1.19e-07	104	164	7	a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WFS1 PLEKHA4 STAT4 CD6 MYH14 BAZ1A RTN4RL2	1.86e-06	156	164	7	09e0702400570089d9012dcf94dfb4827c97e49d
ToppCell	Influenza_Severe-CD4+_CTL\|Influenza_Severe / Disease group and Cell class	TNFRSF25 ADGRB1 STAT4 SPTBN4 CD6 KANK3 PBXIP1	2.59e-06	164	164	7	9ffd40ae1f39290840bea79fa4e73cb7e009f310
ToppCell	Mild-CD4+_T_Exhausted\|World / Disease group and Cell class	TNFRSF25 CORO1B TNFRSF10D LAP3 ARHGAP4 CD6 PBXIP1	3.55e-06	172	164	7	efe68d9477aa873b1637ee689f298120303aa322
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYOC PPP1R3G DNALI1 EXOC3L4 MYH15 TEKT4	3.92e-06	113	164	6	fed408864201218295bac0cc6647953fda8d688e
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYOC PPP1R3G DNALI1 EXOC3L4 MYH15 TEKT4	3.92e-06	113	164	6	c0b8d7a2e3722029e850051bdff77f31f34a8cca
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYOC PPP1R3G DNALI1 EXOC3L4 MYH15 TEKT4	3.92e-06	113	164	6	7e24c0f6a80e10a2a41325d48a87628bd330a1e2
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BICDL2 SMG1 NR4A1 ERN2 MYH14 DLG1 GOLGA8A	4.61e-06	179	164	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 SHMT2 MIB2 GRM3 CARD9 TONSL NOTCH3	4.96e-06	181	164	7	274c0b768925cd5804483303f8c5ebd17a534c41
ToppCell	NS-critical-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TNFRSF25 ZNF775 STAT4 CD6 SOCS1 GOLGA8A PBXIP1	5.33e-06	183	164	7	f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CORO1B TLK1 CD6 SOCS1 PBXIP1	6.59e-06	189	164	7	8130102c41b2978a8b83f765ce383f836a464795
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CORO1B TLK1 CD6 GOLGA8A PBXIP1	6.82e-06	190	164	7	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	severe_COVID-19-CD4+_Tcm\|severe_COVID-19 / disease group, cell group and cell class (v2)	TNFRSF25 CORO1B STAT4 CD6 SOCS1 DDX24 PBXIP1	7.06e-06	191	164	7	1ec86eaf90411ed200dbf51ae0cb5ed8060a7ec7
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	C8orf34 JPH1 MYH14 HSD17B6 ATP11A PARD3 GOLGA8A	7.06e-06	191	164	7	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CORO1B CD6 DDX24 GOLGA8A PBXIP1	7.30e-06	192	164	7	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CORO1B TLK1 CD6 GOLGA8A PBXIP1	7.55e-06	193	164	7	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SMG1 SPTBN1 NCL STAT4 CD6 GOLGA8A PBXIP1	8.63e-06	197	164	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNFRSF25 TLK1 CD6 SOCS1 DDX24 GOLGA8A PBXIP1	9.22e-06	199	164	7	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	Mild/Remission-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 PPP1R3G SPTBN4 KIRREL3 TAS1R2 LRRC73	1.14e-05	136	164	6	1b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	SMG1 OBSCN STAT4 TARS3 GOLGA8A PBXIP1	2.06e-05	151	164	6	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	BICDL2 TNFRSF25 KRT33A RBBP8NL GALNT18 MYH14	2.30e-05	154	164	6	8a643d91896af9b630a715fb284c1523d01ad1a3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CD6 EXOC3L4 GOLGA8A PBXIP1	3.63e-05	167	164	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|356C / Donor, Lineage, Cell class and subclass (all cells)	CCNI2 TNFRSF25 STAT4 CD6 SOCS1 PBXIP1	3.75e-05	168	164	6	9d6ca10c272aea28082c09d469940f7232f6461c
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHG4 TSPOAP1 TG ARHGAP4 AP5B1 BLOC1S3	3.75e-05	168	164	6	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHG4 TSPOAP1 TG ARHGAP4 AP5B1 BLOC1S3	3.75e-05	168	164	6	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHG4 TSPOAP1 TG ARHGAP4 AP5B1 BLOC1S3	3.75e-05	168	164	6	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZMYND15 UNC13D KANK3 DLG2 ABCD1 GOLGA8A	4.01e-05	170	164	6	c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR31 DNALI1 TG DLG2 CTF1 CCDC102A	4.28e-05	172	164	6	b043d4f81dced7fb3326043f68474123be47cc5d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR31 TG NCAPD2 DLG2 PPM1N CCDC102A	4.42e-05	173	164	6	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBSCN NR4A1 TERT MYH14 GOLGA8A NOTCH3	4.56e-05	174	164	6	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NRL PLEKHG4 PLEKHA4 PRPH	4.67e-05	54	164	4	98b31718fa200432cf86b59a52484da101219f96
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NRL PLEKHG4 PLEKHA4 PRPH	4.67e-05	54	164	4	872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARL13A MIB2 TARS3 SLFN13 RASSF1 SOCS1	4.71e-05	175	164	6	0ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARL13A MIB2 TARS3 SLFN13 RASSF1 SOCS1	4.71e-05	175	164	6	0124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARL13A MIB2 TARS3 SLFN13 RASSF1 SOCS1	4.71e-05	175	164	6	e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARL13A MIB2 TARS3 SLFN13 RASSF1 SOCS1	4.71e-05	175	164	6	bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCell	COPD-Lymphoid-ILC_A\|World / Disease state, Lineage and Cell class	KRT33A STAT4 TARS3 SLFN13 SOCS1 GOLGA8A	4.71e-05	175	164	6	e773e330de36f8a0aa9398a176ed7edb5599c582
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	PLEKHA4 ERN2 PROM2 GOLGA8A NOTCH3 CHST3	4.86e-05	176	164	6	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BICDL2 TNFRSF25 TSPOAP1 CD6 SOCS1 DLG2	5.02e-05	177	164	6	fd4a297e519b3959811a462d63feebff76429031
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NOP56 NRL NR4A1 TARS3 DEDD2 SOCS1	5.02e-05	177	164	6	3d1b142aa2bd18df14816abaca356596b297394e
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BICDL2 TNFRSF25 TSPOAP1 CD6 SOCS1 DLG2	5.02e-05	177	164	6	e995230ef207dcd87eab4550617589016ffa9970
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLEKHA4 NIBAN3 CDC42BPB GPC3 TONSL GPATCH11	5.02e-05	177	164	6	3535575686c9700ab72700aae6f2070ebbb50044
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CYP26A1 TERT PROM2 PPM1N	5.02e-05	55	164	4	ed871246b0ada07e8fe87a68584c06986977d0bd
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CYP26A1 TERT PROM2 PPM1N	5.02e-05	55	164	4	51a76e6cb45976ce99a41fb6cd5b94c632ec7c5b
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ADAMTS19 SLC25A41 ARHGAP4 RDH16	5.39e-05	56	164	4	ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ADAMTS19 SLC25A41 ARHGAP4 RDH16	5.39e-05	56	164	4	20a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCell	CV-Severe-4\|Severe / Virus stimulation, Condition and Cluster	BICDL2 PLEKHG4 GAL3ST2 NR4A1 GALNT18 TARS3	5.51e-05	180	164	6	cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 STAT4 CD6 SOCS1 GOLGA8A PBXIP1	5.51e-05	180	164	6	f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 SPTBN1 CORO1B CD6 SOCS1 PBXIP1	5.86e-05	182	164	6	9ba85f621a846531a2a7861e9df695d288c9e149
ToppCell	Control-Lymphoid-T_Regulatory\|Control / Disease state, Lineage and Cell class	TNFRSF25 CORO1B STAT4 CD6 GOLGA8A PBXIP1	5.86e-05	182	164	6	31bb838cc2900f3c9da9f835d79d557a08abb928
ToppCell	COVID-CD4-naive_CD4\|COVID / Condition, Cell_class and T cell subcluster	TNFRSF25 SPTBN1 CORO1B CD6 GOLGA8A PBXIP1	6.22e-05	184	164	6	00db55970d336a301035efe43a4ab4db62627f38
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC25A41 ANK2 MYOC NR4A1 GPC3 LRRC73	6.41e-05	185	164	6	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 STAT4 CD6 SPATA9 DDX24 GOLGA8A	6.41e-05	185	164	6	847257d232b9993cad50c814fd4ffeef52385295
ToppCell	IPF-Lymphoid-T_Regulatory\|IPF / Disease state, Lineage and Cell class	TNFRSF25 CORO1B STAT4 CD6 GOLGA8A PBXIP1	6.41e-05	185	164	6	221cbd09d94cc0947d0e3c1aa14716d17cb2068d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 STAT4 CD6 GOLGA8A PBXIP1 TBCD	6.41e-05	185	164	6	f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GALNT18 GPC3 MYH14 ACAN NOTCH3 CHST3	7.01e-05	188	164	6	c9270517e6940e9793586f67f02431210552f278
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCNI2 STAT4 TG TARS3 CD6 PBXIP1	7.22e-05	189	164	6	df30478b288084a1bd48f660409dcc784040897c
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS19 ANK2 OLFML3 GPC3 ACAN DLG2	7.22e-05	189	164	6	eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS19 ANK2 OLFML3 GPC3 ACAN DLG2	7.22e-05	189	164	6	40764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NR4A1 JPH1 MYH14 DLG2 ATP11A GOLGA8A	7.43e-05	190	164	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	NS-critical-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TNFRSF25 STAT4 CD6 SOCS1 DDX24 GOLGA8A	7.43e-05	190	164	6	84f9f5ac29ff0f929a589b76efa61d4c570e76b0
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TNFRSF25 TARS3 CD6 SOCS1 GOLGA8A PBXIP1	7.43e-05	190	164	6	13dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	TNFRSF25 STAT4 CD6 DDX24 GOLGA8A PBXIP1	7.87e-05	192	164	6	fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCell	IPF-Lymphoid-T\|World / Disease state, Lineage and Cell class	TNFRSF25 CORO1B STAT4 TARS3 CD6 SOCS1	7.87e-05	192	164	6	b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 STAT4 CD6 DDX24 GOLGA8A PBXIP1	8.10e-05	193	164	6	c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCell	LAM-Lymphoid-T-cell\|Lymphoid / Condition, Lineage and Cell class	TNFRSF25 CORO1B CD6 SOCS1 DDX24 PBXIP1	8.10e-05	193	164	6	0d9ceeb3c4d2bf5d13a29bf1b352cf2b70f3ed12
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD4+_Th\|metastatic_Lymph_Node / Location, Cell class and cell subclass	TNFRSF25 STAT4 CD6 SOCS1 PBXIP1 TBCD	8.33e-05	194	164	6	1ce9b4c1fbdbc5e39c03adf7ffba3d0efea81862
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	TNFRSF25 SPTBN1 STAT4 CD6 DDX24 PBXIP1	8.57e-05	195	164	6	a72bb5b1b15dd1ab70ced5622d94499caff8bb6b
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WFS1 SPTBN1 UNC13D HSD17B6 ATP11A GOLGA8A	8.57e-05	195	164	6	68f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WFS1 SPTBN1 UNC13D HSD17B6 ATP11A GOLGA8A	8.57e-05	195	164	6	2a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WFS1 SPTBN1 UNC13D MYH14 ATP11A GOLGA8A	8.82e-05	196	164	6	6731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell	Mild-CD4+_T_activated\|Mild / Disease group and Cell class	TNFRSF25 LAP3 CD6 BAZ1A SOCS1 ABCD1	8.82e-05	196	164	6	daa1c3322d81e649161e889e1d78451d2d425d09
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WFS1 SPTBN1 UNC13D MYH14 ATP11A GOLGA8A	8.82e-05	196	164	6	6856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_T_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NCL STAT4 TARS3 CD6 DDX24 PBXIP1	8.82e-05	196	164	6	c647ce58de4c5bb4ceb1123690e637eae4ae1b82
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 TNFRSF25 ABCA2 STAT4 SLFN13 GOLGA8A	9.06e-05	197	164	6	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_CTL\|Influenza_Severe / Disease, condition lineage and cell class	TNFRSF25 STAT4 SPTBN4 CD6 KANK3 PBXIP1	9.06e-05	197	164	6	8610307434d99e6411a5a6c6769094e9a0749d4d
ToppCell	BL-critical-LOC-Lymphoid-CTL\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TNFRSF25 STAT4 CD6 DDX24 GOLGA8A PBXIP1	9.06e-05	197	164	6	fb70918867fbd111bb192a797dcafed5f39ea299
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Naive_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TNFRSF25 SPTBN1 OBSCN CD6 GOLGA8A PBXIP1	9.06e-05	197	164	6	cf72160f03105876641fa6fdc7405e339eb084c7
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-AT1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ANK2 CYP26A1 KANK3 TRIM62 DLG2 FOXH1	9.06e-05	197	164	6	f7ef62d78336812573148f8bfce401877ec4e29c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 TLK1 CD6 SOCS1 DDX24 PBXIP1	9.32e-05	198	164	6	8a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NCL STAT4 TARS3 CD6 DDX24 PBXIP1	9.32e-05	198	164	6	5024d43b4cf7dea305ed911f1e123ca7fd44e990
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NCL STAT4 TARS3 CD6 DDX24 PBXIP1	9.32e-05	198	164	6	1fa0ea06453d6b979039f63454e7f9c69323a350
ToppCell	distal-Epithelial-Club-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BICDL2 EVPL NR4A1 JPH1 MYH14 HSD17B6	9.32e-05	198	164	6	e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCell	COVID-CD4\|COVID / Condition, Cell_class and T cell subcluster	TNFRSF25 CORO1B STAT4 CD6 SOCS1 PBXIP1	9.32e-05	198	164	6	3b72d3fa96f8cda528c483afdff391385113080d
ToppCell	Biopsy_Control_(H.)-Epithelial-SCGB3A2+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KRT33B EVPL RBBP8NL ERN2 PROM2 HSD17B6	9.32e-05	198	164	6	1fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLK2 SMG1 STAT4 SLFN13 DDX24 GOLGA8A	9.58e-05	199	164	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ANK2 PLEKHA4 COL6A5 PTK7 GPC3 SOCS1	9.58e-05	199	164	6	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	LPS_only-Mesenchymal_fibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	ANK2 COL6A5 PTK7 GPC3 PXDNL SOCS1	9.58e-05	199	164	6	211c3a08f2d484ab7a3368006767289088f0d957
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KRT32 TG PROM2 CTF1 FOXH1 GOLGA8A	9.58e-05	199	164	6	e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCell	10x5'-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	TNFRSF25 STAT4 CD6 SOCS1 GOLGA8A PBXIP1	9.58e-05	199	164	6	32b9f19579448f1775ecb7974c29c60334513c88
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts\|LPS_only / Treatment groups by lineage, cell group, cell type	ANK2 COL6A5 PTK7 GPC3 PXDNL SOCS1	9.58e-05	199	164	6	1a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPTBN1 COL6A5 OLFML3 PTK7 GPC3 KANK3	9.58e-05	199	164	6	212e89d097753790061310373a1fafba773488b6
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	ZNF775 SPTBN1 GALNT18 PTK7 CD6 PBXIP1	9.58e-05	199	164	6	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	JPH1 HSD17B6 SAC3D1 MESP2 CDT1 RTN4RL2	9.58e-05	199	164	6	f0c289523957258d16135c04679db379d43d28d9
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPTBN1 COL6A5 OLFML3 PTK7 GPC3 KANK3	9.58e-05	199	164	6	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Cpne5\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CUBN TG RDH16 RUFY4	9.69e-05	65	164	4	db5db7d5811a714535bdb367c5e2863a3edf89a0
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Cpne5-Inhibitory_Gad1Gad2_Htr3a.Cpne5_(Interneuron,__(candidate_CGE-derived_5))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CUBN TG RDH16 RUFY4	9.69e-05	65	164	4	a4873ffa71ac0016c9abce82cb4e1060946627cd
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Cpne5-Inhibitory_Gad1Gad2_Htr3a.Cpne5_(Interneuron,__(candidate_CGE-derived_5))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CUBN TG RDH16 RUFY4	9.69e-05	65	164	4	9cc767bfb26231af3bdb9423978b68ee42797cf4
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 SPTBN1 COL6A5 PTK7 GPC3 PXDNL	9.85e-05	200	164	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	severe-NK_CD56bright\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARL13A MIB2 TARS3 SLFN13 RASSF1 SOCS1	9.85e-05	200	164	6	82818ab1796fdd0b8be02b341818897595eed841
Drug	NSC34533	NES KRT31 KRT32 KRT33A KRT33B PRPH	2.14e-06	54	160	6	CID000003512
Drug	AC1L1I0J	KRT31 KRT32 KRT33A KRT33B	8.39e-06	19	160	4	CID000004371
Drug	SR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A	TNFRSF25 BCAN CAMTA2 ERN2 CD6 RASSF1 ERMAP MYH15 ABCD1	1.20e-05	199	160	9	6632_DN
Drug	Gibberellic acid [77-06-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A	ABCA2 DNALI1 GPC3 RASSF1 SOCS1 ATP11A ABCD1 WIPF2 PRPH	1.20e-05	199	160	9	7330_DN
Disease	viral hepatitis (is_marker_for)	TERT STAT4	7.99e-05	3	153	2	DOID:1884 (is_marker_for)
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN1 SPTBN4	1.59e-04	4	153	2	DOID:0050882 (implicated_via_orthology)
Disease	Wilson disease (implicated_via_orthology)	ATP7A CYP27B1	2.64e-04	5	153	2	DOID:893 (implicated_via_orthology)
Disease	gallbladder carcinoma (is_implicated_in)	TERT UBR5	2.64e-04	5	153	2	DOID:4948 (is_implicated_in)
Disease	laryngeal carcinoma (is_marker_for)	UBR5 SOCS1	3.95e-04	6	153	2	DOID:2600 (is_marker_for)
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	CAMTA2 KANK3	3.95e-04	6	153	2	EFO_0800611
Disease	Tinnitus	NPBWR1 SPTBN1 C8orf34 DLG2 TNFRSF1A	5.97e-04	130	153	5	HP_0000360
Disease	benign neoplasm (implicated_via_orthology)	DLG1 DLG2	7.33e-04	8	153	2	DOID:0060072 (implicated_via_orthology)
Disease	2-ketocaprylate measurement	HEATR4 DHRS7	1.17e-03	10	153	2	EFO_0800110
Disease	hair color	KRT31 KRT33A GRM3 KIRREL3 PARD3 WIPF2 TBCD	1.23e-03	311	153	7	EFO_0003924
Disease	diffuse scleroderma (is_implicated_in)	IRAK1 STAT4	1.42e-03	11	153	2	DOID:1580 (is_implicated_in)
Disease	invasive ductal carcinoma (is_implicated_in)	UBR5 DLG1	1.42e-03	11	153	2	DOID:3008 (is_implicated_in)
Disease	psoriatic arthritis (is_implicated_in)	IRAK1 STAT4	1.42e-03	11	153	2	DOID:9008 (is_implicated_in)
Disease	biliary liver cirrhosis	STAT4 EXOC3L4 TNFRSF1A	1.55e-03	44	153	3	EFO_0004267
Disease	Multiple Sclerosis	STAT4 CD6 TNFRSF1A	1.65e-03	45	153	3	C0026769
Disease	Multiple Sclerosis, Acute Fulminating	STAT4 CD6 TNFRSF1A	1.65e-03	45	153	3	C0751324
Disease	chronic kidney disease (implicated_via_orthology)	NR4A1 TERT	1.70e-03	12	153	2	DOID:784 (implicated_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG1 DLG2 PARD3	2.11e-03	49	153	3	DOID:0060037 (implicated_via_orthology)
Disease	immature platelet count	TERT TLK1 EXOC3L4 BLOC1S3	2.29e-03	106	153	4	EFO_0803544
Disease	Hamman-Rich syndrome	TERT ATP11A	2.33e-03	14	153	2	C0085786
Disease	trimethylamine-N-oxide measurement	CUBN TAS1R2	2.33e-03	14	153	2	EFO_0010541
Disease	gastroparesis	PXDNL MESP2	3.06e-03	16	153	2	EFO_1000948
Disease	Usual Interstitial Pneumonia	TERT ATP11A	4.31e-03	19	153	2	C4721509
Disease	Hamman-Rich Disease	TERT ATP11A	4.31e-03	19	153	2	C4721508
Disease	eosinophil count	ADAMTS19 SPTBN1 CYP27B1 UNC13D SEC31A ERN2 LINC00336 TERT STAT4 TG NAA25 SOCS1 PLCB3 TNFRSF1A WIPF2 ZNF282	4.63e-03	1488	153	16	EFO_0004842
Disease	Familial Idiopathic Pulmonary Fibrosis	TERT ATP11A	4.77e-03	20	153	2	C4721952

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQRLQELARDARGCE	EXOC3L4	321	Q17RC7
LRGEELSRRLQVVAC	CCDC17	161	Q96LX7
LDAVCRRQAELNPRA	CTF1	101	Q16619
RNATGLILRRCELDE	ADGRB1	606	O14514
QDGRLRVNDCILRVN	DLG1	266	Q12959
ECGRINEDRGIQRLE	GRM3	56	Q14832
CNAGIIRALQKRLRE	GPR31	196	O00270
QARLVEECNGRRAKL	ABHD16A	241	O95870
RCARLQGDNLEERTE	C8orf34	411	Q49A92
RLLCHLQLAQDREAR	CCNI2	121	Q6ZMN8
CLQRARELGARVRAL	CDT1	126	Q9H211
GHVRLARCLEELQRQ	CAMTA2	801	O94983
RALRALVKEQGDRIC	CORO1B	461	Q9BR76
QGSALRDQLRRRCQE	CCDC142	256	Q17RM4
RDQLRRRCQEEGDLL	CCDC142	261	Q17RM4
RVEPCSAIRNLERRN	ARL13A	161	Q5H913
ELERRGQCDESNLRL	DEDD2	71	Q8WXF8
QVRDCRLVGLLDLAL	AMY2B	171	P19961
ELERVKRRCLENGNL	DHRS7	86	Q9Y394
QCEAQLLAVEGRLRR	CARD9	401	Q9H257
RNNGARLQCRILEVL	BAZ1A	126	Q9NRL2
SCVANIERNLRREEG	ATP7A	501	Q04656
GRDLRALREADFQAC	RTN4RL2	296	Q86UN3
RRGCVQALALAFALR	TP53I13	166	Q8NBR0
LERANALRIARGTAC	RASSF1	26	Q9NS23
AGLELCQVFARQRAR	RIMBP3B	456	A6NNM3
AGLELCQVFARQRAR	RIMBP3C	456	A6NJZ7
IAALQRECRELQARL	TSPOAP1	231	O95153
QLSNGTLIRARERDC	ADAMTS19	1006	Q8TE59
ERRLAALEERLAQCQ	OLFML3	31	Q9NRN5
QREKDRQCRGLELIA	SHMT2	61	P34897
NCDQAAQRLERVRGR	NIBAN3	496	Q86XR2
NGNSEVVQLLLDRRC	POTEB2	146	H3BUK9
PRRVEELQNRIASCL	NR4A1	521	P22736
RRLQELCQILGEAVA	ABCD1	711	P33897
RCLLRNGALVDARAR	ANK2	481	Q01484
IRAAVAAGCRQIQDL	LAP3	121	P28838
ARVTCAENRALRLVD	CD6	151	P30203
NANLCRAIVRSGARL	ANKFY1	1056	Q9P2R3
GTLNNVVCDLVRRLR	CYP27B1	156	O15528
EGLAQRNLPLIRCQE	BCAN	846	Q96GW7
LLGVRAQCRRASDLA	CASKIN1	976	Q8WXD9
SRARALPDRALVNCQ	EXOSC4	61	Q9NPD3
CRLAQFIGNRRELNE	NOP56	211	O00567
TLRRGDRVQVLSQDC	MAP3K10	36	Q02779
CRLQEAARARPDANL	KAZALD1	146	Q96I82
PAEALRLQNTALCRR	FOXH1	116	O75593
LRCQLGDRLNVEVDA	KRT31	201	Q15323
ALDINECLRGARRDL	GPC3	191	P51654
CALLLRRGAEADARD	ASB18	276	Q6ZVZ8
LRECFGLVRREVQLL	ERN2	551	Q76MJ5
LSEESLQCRRRQRGD	MESP2	141	Q0VG99
LRCQLGDRLNIEVDA	KRT32	241	Q14532
LAARQECDIARAVAR	JPH1	396	Q9HDC5
RARLAEQLRAEAELC	MYH14	906	Q7Z406
RRQIQSLTCEVDGLR	PRPH	316	P41219
LQRARDQADQECGRL	EVPL	1581	Q92817
ECGRLQQELRALERQ	EVPL	1591	Q92817
AIRRELALDAALGCR	PPM1N	336	Q8N819
CRSKRLQQRRGLEAE	NRL	176	P54845
GERQLLCIARAVLRN	ABCC11	1281	Q96J66
REAAAQIGVRLEQLC	NOTCH3	1041	Q9UM47
EVARLRRGQCPQTRD	MYOC	176	Q99972
VAGRCQQLRLARERT	NES	91	P48681
VNGLRRVLDEITLCR	KRT25	186	Q7Z3Z0
LRCQLGDRLNVEVDA	KRT33A	201	O76009
DAIGQACRQLRVLDV	LRRC29	171	Q8WV35
DLQQGLLRVCRALLR	AP5B1	571	Q2VPB7
ICSRERRLGQNGIED	CDC42BPB	321	Q9Y5S2
GRDVFAALRCAQALR	LINC00336	21	Q6ZUF6
RDQTELRLCERSGQR	IRAK1	51	P51617
NSCNKREIEGRAIRL	NCL	541	P19338
FQEAANECRRLGARL	ACAN	266	P16112
SLRQDGARCELQIRG	OBSCN	3671	Q5VST9
RQDGSRCELQIRGLA	OBSCN	3761	Q5VST9
CQEQRARLPQEIRRS	PLCB3	1176	Q01970
QGRDLREQLAEGCRL	NBPF3	196	Q9H094
LEARLRQAGCTDVRG	PXDNL	1386	A1KZ92
LRVLENRLRAGLCDR	RBBP8NL	61	Q8NC74
RLARTCGREQLANPI	CUBN	1576	O60494
RARRRELASLCLQDG	GAL3ST2	311	Q9H3Q3
LERLKILRQRCGLDN	CKAP5	1936	Q14008
RGLEQRCLRLSAREA	HDAC10	41	Q969S8
GDLRRSQRACQQLDV	GPATCH11	186	Q8N954
ARQLDARGLRVLAAC	HSD17B6	46	O14756
LERAERRGLQQACGR	CROCC2	681	H7BZ55
RNLDELVREILGRCT	GAS2L1	206	Q99501
NGENQTLERLRRCAL	COL6A5	1926	A8TX70
AQGECEARGRELARL	CCDC102A	146	Q96A19
RRAACLAAGALQIRD	HEATR4	746	Q86WZ0
DDNRCLVDVNSRPRL	GALNT18	526	Q6P9A2
LCGNNRTIEPEALRR	ABCA2	416	Q9BZC7
RLARGDLCALAERLD	BLOC1S3	161	Q6QNY0
RELDALRGQCQAQAL	BICDL2	176	A1A5D9
INCAERGLLLLRVRD	DNALI1	141	O14645
NLRQLRCLVVDEADR	DDX24	461	Q9GZR7
RLRNLEQFARLEDCV	DDX24	626	Q9GZR7
LLLDTGACEVNRQNR	KANK3	641	Q6NY19
ECQAIQAAIRSRPAR	KIRREL3	126	Q8IZU9
RIEQNIRAKICGLRA	CYP26A1	246	O43174
DGRLRVNDCILRVNE	DLG2	141	Q15700
NLLALDGLREARDLC	SAC3D1	326	A6NKF1
QERARVIRAACALLN	SLFN13	41	Q68D06
RRLQVRAAEQLCREQ	CFAP74	196	Q9C0B2
LCREQEALGKVERNR	CFAP74	206	Q9C0B2
LRAAVNLAERCEQRL	CNTNAP3B	666	Q96NU0
NVLRQRCELLQRAGE	C19orf25	81	Q9UFG5
FARLDDEQGRRQCVL	NPBWR1	176	P48145
NDCIVRINDGDLRNR	PARD3	321	Q8TEW0
QILIREGRCDVNVRN	MIB2	651	Q96AX9
RGCLQEDVQRVQRLS	FAM74A4	76	Q5TZK3
LILSEDQRCVRLGDR	ERMAP	251	Q96PL5
CISLLNRGQKERLRE	GOLGA8A	351	A7E2F4
TREVAQLRAENCDLR	TARS3	51	A2RTX5
EELVQRNRLICRRNP	TSEN2	276	Q8NCE0
AVNICAARGLQDVLR	CCT6B	21	Q92526
LDFRRRLEALLQNCQ	PLEKHG4	331	Q58EX7
ARQLDARGLRVLAAC	RDH16	46	O75452
AGLELCQVFARQRAR	RIMBP3	456	Q9UFD9
LCGQDRLLRRLQEEI	PLEKHA4	371	Q9H4M7
EIRQGDNCDSIIRRL	LARS1	1086	Q9P2J5
AEAQRGARRLERCIK	MYH15	1846	Q9Y2K3
NGNSEVVQLLLDRRC	POTEB	146	A0A0A6YYL3
CQPRARGLQEARAAL	PPP1R3E	131	Q9H7J1
RLLTQRICLERAEAG	PPP1R3E	156	Q9H7J1
LLQQRRSVLRGCLEQ	SMG1	2626	Q96Q15
GELQALREQLSRCQE	RUFY4	441	Q6ZNE9
ARLEQGGCTNDRREL	SHISA3	71	A0PJX4
LDCARQILQREGTRA	SLC25A41	226	Q8N5S1
LRLQCDAVNLAFGRR	TEKT4	281	Q8WW24
PSAAAERLQRQRVCL	PPP1R3G	206	B7ZBB8
ELCRQRIVATVGREN	SOCS1	176	O15524
QLACRLLELRDISGR	SPATA9	96	Q9BWV2
QLRCLELQGELRREL	ARHGAP4	31	P98171
QELCQLAAERRARLE	SPTBN1	621	Q01082
DDLLRANCDLRRQID	TLK2	236	Q86UE8
DGLREEEVQRLRGNC	CHST3	331	Q7LGC8
EEVQRLRGNCESIRL	CHST3	336	Q7LGC8
LEQAVSGELCRRRVL	NCAPD2	941	Q15021
ARVERNAVEGLRTLC	ATP11A	596	P98196
RLLEQAEAEGCQRRR	TNFRSF10D	316	Q9UBN6
CQRRRLLVPVNDADS	TNFRSF10D	326	Q9UBN6
QDRAFLRRLLAQECA	RNF31	686	Q96EP0
EGRIDDLLRANCDLR	TLK1	236	Q9UKI8
DLLRANCDLRRQIDE	TLK1	241	Q9UKI8
RRNRQLEVCLGEVEN	TEP1	951	Q99973
LQQLRARLQGLEADC	PBXIP1	331	Q96AQ6
RDRLLELLQEARCQG	PROM2	291	Q8N271
SNCLREERRILAAAN	STAT4	106	Q14765
ACIEGQLRRVQDLVR	TONSL	536	Q96HA7
ELIQDAAARRACRLQ	ZNF775	226	Q96BV0
RRALLQQALRCGEEL	SPTBN4	711	Q9H254
GLDGCVEDLRSRLQR	TNFRSF25	401	Q93038
QLLGERVARRDICIA	TAS1R2	221	Q8TE23
DAELAVVREQRNRLC	TBCD	1161	Q9BTW9
VVREQRNRLCDLLGV	TBCD	1166	Q9BTW9
RDEQRGRGALLQDIC	WIPF2	31	Q8TF74
QLRDRLCRAQGEPVA	SEC31A	781	O94979
QDALQGRRALLRCEV	PTK7	41	Q13308
SLQGQNCRLLLREEA	TG	2166	P01266
DAILNARRAARPCQA	TRIM62	81	Q9BVG3
QLQPRAELLQDICRR	VMAC	96	Q2NL98
DRLELQNGRCLREAQ	TNFRSF1A	386	P19438
LEGRCRQLEAQIRRL	ZMYND15	36	Q9H091
DFLGNVVLRLQDLRC	UNC13D	241	Q70J99
VARVLQRLCERGAKN	TERT	81	O14746
GRLDQAVLDLQRCVS	UNC45A	106	Q9H3U1
RRAQAEPINLDSCLR	USP32	1226	Q8NFA0
DTLCVRGQRGLEERA	ZNF282	296	Q9UDV7
NTEARLNCFRNIGRI	UBR5	2521	O95071
CRAENRLGSQQRALD	SIGLEC16	306	A6NMB1
QGRREAVKLLRRCLA	WFS1	136	O76024
LRCQLGDRLNVEVDA	KRT33B	201	Q14525
AEVRDICRGLRDNAV	LRRC73	16	Q5JTD7
ICRGLRDNAVRLLSL	LRRC73	21	Q5JTD7
AKLELIRRLRSQGCN	NAA25	326	Q14CX7