Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	4-hydroxybutyrate receptor activity	SLC52A1 SLC52A2	1.63e-05	2	81	2	GO:0062124
GeneOntologyMolecularFunction	riboflavin transmembrane transporter activity	SLC52A1 SLC52A2	2.41e-04	6	81	2	GO:0032217
GeneOntologyMolecularFunction	virus receptor activity	TYRO3 SLC52A1 DAG1 SLC52A2	3.96e-04	85	81	4	GO:0001618
GeneOntologyMolecularFunction	exogenous protein binding	TYRO3 SLC52A1 DAG1 SLC52A2	4.14e-04	86	81	4	GO:0140272
GeneOntologyMolecularFunction	protein domain specific binding	ADAM19 EHMT2 CD2AP DAG1 IKZF1 POU5F1B PAX6 PLXND1 TRAK2 FOXH1 SON	7.89e-04	875	81	11	GO:0019904
Domain	Formin_homology_1	DIAPH1 FMN2	1.81e-05	2	80	2	IPR009408
Domain	Drf_FH1	DIAPH1 FMN2	1.81e-05	2	80	2	PF06346
Domain	Riboflavin_transptr	SLC52A1 SLC52A2	5.42e-05	3	80	2	IPR009357
Domain	DUF1011	SLC52A1 SLC52A2	5.42e-05	3	80	2	PF06237
Domain	-	RASA4 RASA4B	5.42e-05	3	80	2	4.10.1130.10
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	1.08e-04	4	80	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	1.08e-04	4	80	2	PF01557
Domain	-	FAHD2B FAHD2A	1.08e-04	4	80	2	3.90.850.10
Domain	DUF1908	MAST1 MAST2	1.08e-04	4	80	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST1 MAST2	1.08e-04	4	80	2	IPR015022
Domain	MAST_pre-PK_dom	MAST1 MAST2	1.08e-04	4	80	2	IPR023142
Domain	-	MAST1 MAST2	1.08e-04	4	80	2	1.20.1480.20
Domain	BTK	RASA4 RASA4B	6.40e-04	9	80	2	SM00107
Domain	Znf_Btk_motif	RASA4 RASA4B	6.40e-04	9	80	2	IPR001562
Domain	BTK	RASA4 RASA4B	6.40e-04	9	80	2	PF00779
Domain	ZF_BTK	RASA4 RASA4B	6.40e-04	9	80	2	PS51113
Domain	Methyl_CpG_DNA-bd	MBD1 MBD6	9.72e-04	11	80	2	IPR001739
Domain	MBD	MBD1 MBD6	9.72e-04	11	80	2	PF01429
Domain	DNA-bd_dom	MBD1 MBD6	9.72e-04	11	80	2	IPR016177
Domain	MBD	MBD1 MBD6	9.72e-04	11	80	2	SM00391
Domain	MBD	MBD1 MBD6	9.72e-04	11	80	2	PS50982
Domain	RasGAP	RASA4 RASA4B	1.59e-03	14	80	2	SM00323
Domain	RasGAP_CS	RASA4 RASA4B	1.59e-03	14	80	2	IPR023152
Domain	RasGAP	RASA4 RASA4B	1.83e-03	15	80	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA4 RASA4B	1.83e-03	15	80	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA4 RASA4B	1.83e-03	15	80	2	PS50018
Domain	FH2	DIAPH1 FMN2	1.83e-03	15	80	2	PS51444
Domain	FH2_Formin	DIAPH1 FMN2	1.83e-03	15	80	2	IPR015425
Domain	FH2	DIAPH1 FMN2	1.83e-03	15	80	2	PF02181
Domain	FH2	DIAPH1 FMN2	1.83e-03	15	80	2	SM00498
Domain	Post-SET_dom	KMT2C EHMT2	2.09e-03	16	80	2	IPR003616
Domain	PostSET	KMT2C EHMT2	2.09e-03	16	80	2	SM00508
Domain	-	RASA4 RASA4B	2.09e-03	16	80	2	1.10.506.10
Domain	POST_SET	KMT2C EHMT2	2.09e-03	16	80	2	PS50868
Domain	RasGAP_dom	RASA4 RASA4B	2.65e-03	18	80	2	IPR001936
Domain	Homeodomain-like	ADNP2 GON4L SIX5 POU5F1B PAX6 PC	3.01e-03	332	80	6	IPR009057
Domain	DEP_dom	RAPGEF4 FMN2	4.32e-03	23	80	2	IPR000591
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SP1 KMT2C ALMS1 MAST1 C15orf39 PERM1 SIX5 MAGEE1 TSGA10IP	6.84e-09	233	86	9	37704626
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARG2 ISLR2 TBC1D10B ALMS1 EHMT2 BICRA MBD1 DIAPH1 ADNP2 FMN2 MAST2 SAP130 CDH16 HMG20B ZNF574 SON	1.33e-08	1116	86	16	31753913
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C ALMS1 EHMT2 BICRA DTL C15orf39 PROSER1 MBD6 HMG20B	2.28e-07	351	86	9	38297188
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B TBC1D10B ALMS1 CD2AP MBD1 DTL USP43 FMN2 MAST2 PC WNK1 TAB3	1.40e-06	861	86	12	36931259
Pubmed	Human transcription factor protein interaction networks.	SP1 KMT2C ALMS1 EHMT2 BICRA ZNF638 GON4L C15orf39 SIX5 PROSER1 PAX6 MBD6 SAP130 TAB3 HMG20B	2.09e-06	1429	86	15	35140242
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ALMS1 BICRA C15orf39 PROSER1 DTX2 TAB3	2.22e-06	152	86	6	38360978
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TICRR KMT2C SEC24C KRT84 CD2AP DTL DIAPH1 ZNF638 DAG1 FMN2 DTX2 WNK1 NPNT	2.58e-06	1084	86	13	11544199
Pubmed	Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice.	SLC52A1 PAX6 SLC52A2	3.16e-06	12	86	3	33116204
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DIP2B ISLR2 KMT2C LRCH2 DTX2	5.95e-06	103	86	5	10819331
Pubmed	Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system.	FMN2 PAX6	6.04e-06	2	86	2	10781961
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	6.04e-06	2	86	2	11448776
Pubmed	Matrix metalloproteinase‑2 regulates MDA‑MB‑231 breast cancer cell invasion induced by active mammalian diaphanous-related formin 1.	DIAPH1 MMP2	6.04e-06	2	86	2	27177153
Pubmed	Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway.	SP1 MMP2	6.04e-06	2	86	2	16453304
Pubmed	Identification of receptors for pig endogenous retrovirus.	SLC52A1 SLC52A2	6.04e-06	2	86	2	12740431
Pubmed	Treponema denticola-Induced RASA4 Upregulation Mediates Cytoskeletal Dysfunction and MMP-2 Activity in Periodontal Fibroblasts.	RASA4 MMP2	6.04e-06	2	86	2	34094999
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	6.04e-06	2	86	2	15774318
Pubmed	Screening of Tumor Suppressor Genes in Metastatic Colorectal Cancer.	SP1 MBD1	6.04e-06	2	86	2	28473981
Pubmed	Riboflavin uptake transporter Slc52a2 (RFVT2) is upregulated in the mouse mammary gland during lactation.	SLC52A1 SLC52A2	6.04e-06	2	86	2	26791833
Pubmed	The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6.	DIAPH1 PAX6	6.04e-06	2	86	2	12324464
Pubmed	Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice.	SLC52A1 SLC52A2	6.04e-06	2	86	2	33518683
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	6.04e-06	2	86	2	16041389
Pubmed	Involvement of riboflavin transporter RFVT2/Slc52a2 in hepatic homeostasis of riboflavin in mice.	SLC52A1 SLC52A2	6.04e-06	2	86	2	23911957
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KMT2C BICRA DIAPH1 ADNP2 GON4L C15orf39 SIX5 ELK1	6.68e-06	398	86	8	35016035
Pubmed	Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.	MAST1 PAX6 MAST2	1.37e-05	19	86	3	30449657
Pubmed	A census of human transcription factors: function, expression and evolution.	SP1 SKOR2 THAP8 ADNP2 GON4L SIX5 IKZF1 ELK1 POU5F1B PAX6 FOXH1	1.49e-05	908	86	11	19274049
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KMT2C BICRA THAP8 C15orf39 PAPLN DTX2 PLXND1 SLC52A2 MBD6 MAST2 PC WNK1	1.75e-05	1105	86	12	35748872
Pubmed	SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.	SLC52A1 SLC52A2	1.81e-05	3	86	2	26976849
Pubmed	Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.	MAST1 MAST2	1.81e-05	3	86	2	22101766
Pubmed	Stimulation of mouse Cyp1b1 during adipogenesis: characterization of promoter activation by the transcription factor Pax6.	SP1 PAX6	1.81e-05	3	86	2	23376040
Pubmed	The Expression of Riboflavin Transporters in Human Colorectal Cancer.	SLC52A1 SLC52A2	1.81e-05	3	86	2	29715086
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	1.81e-05	3	86	2	25637021
Pubmed	Riboflavin Transporter Deficiency	SLC52A1 SLC52A2	1.81e-05	3	86	2	26072523
Pubmed	Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing.	SP1 ELK1	1.81e-05	3	86	2	17804646
Pubmed	Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.	SLC52A1 SLC52A2	1.81e-05	3	86	2	23506902
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	1.81e-05	3	86	2	38287013
Pubmed	MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains.	DAG1 MMP2	1.81e-05	3	86	2	21865464
Pubmed	Functional characterization of the proximal promoter of the murine pyruvate carboxylase gene in hepatocytes: role of multiple gc boxes.	SP1 PC	1.81e-05	3	86	2	21745612
Pubmed	Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.	SLC52A1 SLC52A2	1.81e-05	3	86	2	24139842
Pubmed	G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.	EHMT2 POU5F1B	1.81e-05	3	86	2	16415856
Pubmed	Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene.	SP1 MMP2	1.81e-05	3	86	2	15317818
Pubmed	CREB and Sp1 regulate the human CD2AP gene promoter activity in renal tubular epithelial cells.	SP1 CD2AP	1.81e-05	3	86	2	18396147
Pubmed	Disease-causing point-mutations in metal-binding domains of Wilson disease protein decrease stability and increase structural dynamics.	MBD1 MBD6	1.81e-05	3	86	2	27744583
Pubmed	PAX6 Promoter Methylation Correlates with MDA-MB-231 Cell Migration, and Expression of MMP2 and MMP9.	PAX6 MMP2	1.81e-05	3	86	2	30362313
Pubmed	Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.	SLC52A1 SLC52A2	1.81e-05	3	86	2	20463145
Pubmed	The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.	SP1 POU5F1B PAX6	2.85e-05	24	86	3	16582099
Pubmed	MCAF mediates MBD1-dependent transcriptional repression.	SP1 MBD1	3.61e-05	4	86	2	12665582
Pubmed	SP1-mediated lncRNA PVT1 modulates the proliferation and apoptosis of lens epithelial cells in diabetic cataract via miR-214-3p/MMP2 axis.	SP1 MMP2	3.61e-05	4	86	2	31755246
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST1 MAST2	3.61e-05	4	86	2	15951562
Pubmed	Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1.	SP1 ALMS1	3.61e-05	4	86	2	20381594
Pubmed	p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.	SP1 MMP2	3.61e-05	4	86	2	16575904
Pubmed	Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.	RASA4 RASA4B	3.61e-05	4	86	2	16234249
Pubmed	Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.	RASA4 RASA4B	3.61e-05	4	86	2	21460216
Pubmed	Activity-dependent neuroprotective protein: a novel gene essential for brain formation.	POU5F1B PAX6	3.61e-05	4	86	2	12888219
Pubmed	Cleavage of β-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9.	DAG1 MMP2	3.61e-05	4	86	2	28821434
Pubmed	Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.	MAST1 MAST2	3.61e-05	4	86	2	10404183
Pubmed	Genomic analysis of gastrulation and organogenesis in the mouse.	POU5F1B PAX6 MYBPC3	3.64e-05	26	86	3	18061570
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TICRR IBA57 ARSL EHMT2 DAG1 GON4L CPXM1 SLC52A2 ZNF385C MAST2 PC MUTYH	4.41e-05	1215	86	12	15146197
Pubmed	Isolation and characterization of proteins associated with histone H3 tails in vivo.	KMT2C EHMT2 SAP130	5.65e-05	30	86	3	17403666
Pubmed	Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration.	DAG1 MMP2	6.01e-05	5	86	2	25704809
Pubmed	RhoGDIβ promotes Sp1/MMP-2 expression and bladder cancer invasion through perturbing miR-200c-targeted JNK2 protein translation.	SP1 MMP2	6.01e-05	5	86	2	28846829
Pubmed	Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry.	TYRO3 DAG1	6.01e-05	5	86	2	22156524
Pubmed	[Expression of regulatory genes Oct-4, Pax-6, Prox-1, Ptx-2 at the initial stages of differentiation of embryonic stem cells in vitro].	POU5F1B PAX6	6.01e-05	5	86	2	12816048
Pubmed	Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins.	SP1 MBD1	6.01e-05	5	86	2	15691849
Pubmed	Defects in tangential neuronal migration of pontine nuclei neurons in the Largemyd mouse are associated with stalled migration in the ventrolateral hindbrain.	DAG1 PAX6	6.01e-05	5	86	2	16819976
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2B CPEB3 ADNP2 MAST2	6.63e-05	87	86	4	12465718
Pubmed	Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells.	POU5F1B PAX6 MAGEE1	7.55e-05	33	86	3	31143371
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ALMS1 EHMT2 CD2AP C15orf39 POU5F1B PC HMG20B	8.18e-05	418	86	7	34709266
Pubmed	High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.	SP1 KMT2C ADNP2 POU5F1B	8.97e-05	94	86	4	16325481
Pubmed	The SDF-1/CXCR4 pathway and the development of the cerebellar system.	PAX6 PLXND1	9.01e-05	6	86	2	16262623
Pubmed	Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.	POU5F1B PAX6	9.01e-05	6	86	2	12923055
Pubmed	Human BAHD1 promotes heterochromatic gene silencing.	SP1 MBD1	9.01e-05	6	86	2	19666599
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SP1 BICRA SCN1A MAGEE1 WNK1 SAP130 SON	9.76e-05	430	86	7	35044719
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	FRMPD2 MAST1 MAST2	9.83e-05	36	86	3	26053890
Pubmed	A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.	ISLR2 EHMT2 PAX6	1.16e-04	38	86	3	32541003
Pubmed	A multimodal cell census and atlas of the mammalian primary motor cortex.	PLXND1 NPNT	1.26e-04	7	86	2	34616075
Pubmed	Mice lacking DCAF2 in placenta die at the gastrulation stage.	DTL POU5F1B	1.26e-04	7	86	2	35711069
Pubmed	Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter.	SP1 POU5F1B	1.26e-04	7	86	2	21360626
Pubmed	Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.	SP1 MBD1	1.26e-04	7	86	2	25363021
Pubmed	Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro.	POU5F1B PC	1.26e-04	7	86	2	28254784
Pubmed	Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.	MBD1 POU5F1B	1.26e-04	7	86	2	20062064
Pubmed	Dynamics of Setdb1 expression in early mouse development.	EHMT2 POU5F1B	1.26e-04	7	86	2	22504302
Pubmed	TAF4b transcription networks regulating early oocyte differentiation.	SP1 POU5F1B	1.26e-04	7	86	2	35043944
Pubmed	Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.	KMT2C SEC24C PC	1.45e-04	41	86	3	34638806
Pubmed	Diversity of two forms of DNA methylation in the brain.	MBD1 POU5F1B	1.68e-04	8	86	2	24653733
Pubmed	Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.	RASA4 RASA4B	1.68e-04	8	86	2	10810084
Pubmed	Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans.	DIAPH1 PAX6	1.68e-04	8	86	2	24781755
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	SP1 EHMT2 BICRA CD2AP DAG1 FOXH1	1.70e-04	329	86	6	17474147
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	TICRR EHMT2 DTL ADNP2	2.02e-04	116	86	4	30804394
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B TBC1D10B ZNF638 GON4L C15orf39 PAPLN MAST2 ZNF574	2.10e-04	650	86	8	38777146
Pubmed	In vivo evidence for unbiased Ikaros retinal lineages using an Ikaros-Cre mouse line driving clonal recombination.	IKZF1 PAX6	2.15e-04	9	86	2	23074133
Pubmed	Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.	PAX6 PLXND1	2.15e-04	9	86	2	34235142
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ALMS1 EHMT2 GON4L MMP2 MAST2 WNK1 SON	2.37e-04	497	86	7	23414517
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	SP1 EHMT2 DTL ZNF638 WNK1 ZNF574 SON	2.55e-04	503	86	7	16964243
Pubmed	Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum.	SKOR2 PAX6	2.68e-04	10	86	2	20809939
Pubmed	Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system.	POU5F1B PAX6	2.68e-04	10	86	2	22223620
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	SEC24C CD2AP ZNF638 IKZF1 PC ARCN1	3.20e-04	370	86	6	22922362
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ARG2 ADAM19 EHMT2 MBD1 RAPGEF4 ADNP2 MAST1 FMN2 PAX6 PC ARCN1	3.25e-04	1285	86	11	35914814
Pubmed	MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life.	DIAPH1 PAX6	3.28e-04	11	86	2	28790189
Pubmed	Basement membrane remodelling regulates mouse embryogenesis.	POU5F1B MMP2	3.28e-04	11	86	2	32523119
Pubmed	Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.	IKZF1 PAX6	3.28e-04	11	86	2	23638021
Interaction	NFIX interactions	KMT2C EHMT2 BICRA DTX2 PAX6 PC SAP130 MYBPC3	3.63e-06	227	81	8	int:NFIX
Interaction	HNF1B interactions	KMT2C BICRA PROSER1 PAX6 MBD6 SAP130 HMG20B	1.14e-05	190	81	7	int:HNF1B
Interaction	PAX9 interactions	KMT2C EHMT2 C15orf39 PROSER1 SAP130 HMG20B	1.40e-05	130	81	6	int:PAX9
Interaction	FHL2 interactions	SP1 ALMS1 ZNF638 SIX5 IKZF1 DTX2 WNK1 SAP130 HMG20B	2.99e-05	396	81	9	int:FHL2
Interaction	SP7 interactions	KMT2C EHMT2 BICRA ZNF638 C15orf39 PROSER1 SAP130 HMG20B	3.03e-05	304	81	8	int:SP7
Interaction	EYA4 interactions	ALMS1 BICRA C15orf39 SIX5 PROSER1 DTX2 TAB3	5.54e-05	243	81	7	int:EYA4
Interaction	CRX interactions	SP1 KMT2C EHMT2 BICRA C15orf39 PROSER1 FOXH1	7.31e-05	254	81	7	int:CRX
Interaction	NFYC interactions	SP1 ALMS1 BICRA ADNP2 GON4L PAX6	7.93e-05	177	81	6	int:NFYC
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	3.33e-04	10	50	2	830
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	MBD1 MBD6	4.06e-04	11	50	2	1025
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2C RAPGEF4 FMN2 PAX6 PC SON	2.02e-06	195	85	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2C RAPGEF4 FMN2 PAX6 PC SON	2.02e-06	195	85	6	7796ea9247f4c63762f0de8490fed08b9717fa23
Disease	Brown-Vialetto-Van Laere syndrome (implicated_via_orthology)	SLC52A1 SLC52A2	2.07e-05	3	78	2	DOID:0050694 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	KMT2C SAP130 SON MYBPC3	3.43e-05	69	78	4	DOID:1682 (implicated_via_orthology)
Disease	transient cerebral ischemia (biomarker_via_orthology)	MBD1 ELK1 PAX6 MMP2 WNK1	6.18e-05	157	78	5	DOID:224 (biomarker_via_orthology)
Disease	blood metabolite measurement	ALMS1 FOXH1	1.15e-03	19	78	2	EFO_0005664
Disease	mean reticulocyte volume	PLIN4 SP1 RETREG2 MBD1 ZNF638 MAST1 C15orf39 IKZF1	1.23e-03	799	78	8	EFO_0010701
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	BICRA PC	1.40e-03	21	78	2	EFO_0000180, Orphanet_391311
Disease	lung adenocarcinoma (is_marker_for)	KMT2C EHMT2 IKZF1	1.50e-03	85	78	3	DOID:3910 (is_marker_for)
Disease	smoking status measurement, chronic obstructive pulmonary disease	ADAM19 EHMT2 NPNT	1.66e-03	88	78	3	EFO_0000341, EFO_0006527
Disease	Adenoid Cystic Carcinoma	KMT2C DTL SON	2.39e-03	100	78	3	C0010606
Disease	primary biliary cholangitis (biomarker_via_orthology)	DAG1 MMP2	2.49e-03	28	78	2	DOID:12236 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	KMT2C ADAM19 FRMPD2 MMP2 FOXH1 WNK1 MUTYH	2.57e-03	702	78	7	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
VVSPIPTLASGAPGE	ZNF385C	126	Q66K41
SVDGLSTPVVLSPGP	ELK1	411	P19419
DPTLAPATGTPVVGG	ARG2	256	P78540
PGVLPAGRVIGEPTS	ARSL	396	P51690
PPESVGPVVAGVLVA	ADAM19	696	Q9H013
SVAPGPVDQTIGTPT	ALMS1	1456	Q8TCU4
DPLPTSGITPGATVL	IBA57	286	Q5T440
VTAGPLVTPTPAGTL	CPXM1	91	Q96SM3
VTIPRGDGVTPPAGT	EHMT2	546	Q96KQ7
ETVLAGPTSPIPSLG	CD2AP	181	Q9Y5K6
IEGAGTSISEPPSPI	DTL	611	Q9NZJ0
VGIPSPSSLPGGTAI	DIAPH1	661	O60610
PGVLPVSPSVTPGVL	ADNP2	416	Q6IQ32
TLAPVSVTLPVPPGG	ADNP2	616	Q6IQ32
SVTLPVPPGGLATVA	ADNP2	621	Q6IQ32
IPGGTVVLEPPVLSG	ISLR2	276	Q6UXK2
IDLGTGPTPTLGPVT	MMP2	451	P08253
GAEAGTVPTSPGKVP	RASA4	751	O43374
GAEAGTVPTSPGKVP	RASA4B	751	C9J798
VTGHAIPVTPAGPGL	QRICH2	1436	Q9H0J4
PLLLVIGTGGTVPSP	LRRC3C	31	A6NJW4
LISPGVSVPVQVPGS	PAX6	396	P26367
GEVFPPVSVITLGSP	POU5F1B	341	Q06416
IPTPTVSPGVPGVVT	MUC16	10921	Q8WXI7
VVPSPVLQSPSEGLG	MBD6	486	Q96DN6
VGGVGVPAAPSITAV	KRT84	126	Q9NSB2
GVSQLPGPVPTSGVT	KMT2C	2351	Q8NEZ4
SSSPLVPGTLGEVPA	MAGEA5P	41	P43359
VLPIPGEGLSTSVPP	MAGEE1	356	Q9HCI5
PLPGPTRVEGETVQG	FOXH1	221	O75593
VPQVGLVGPASVTFP	GREB1	346	Q4ZG55
TIAPAASTPPGGITV	NPNT	356	Q6UXI9
PVTTIIAPPGHTGVA	DTX2	181	Q86UW9
VPTVVGIPDGTAVVG	DAG1	61	Q14118
PGTAVLTSPVLVPGC	MBD1	511	Q9UIS9
EIVCVTGPAPGPLSG	PLXND1	946	Q9Y4D7
VIPVNSAGSPVGDVP	DIP2B	776	Q9P265
PGDVILTGTPPGVGV	FAHD2A	271	Q96GK7
VQTPPGGSEVVPVIS	IKZF1	331	Q13422
SGEAGTPLVPIVVEP	MAST1	1426	Q9Y2H9
PTPVIAGGSTPSVAG	PROSER1	446	Q86XN7
AGGGVTVTVTGPPAP	CACNG8	376	Q8WXS5
AGEAVPGPLPLGVSV	HEATR5B	766	Q9P2D3
VGVGVGVPSPLNPIS	CPEB3	276	Q8NE35
PGDVILTGTPPGVGV	FAHD2B	271	Q6P2I3
PGIFISSIIPGGPAE	FRMPD2	801	Q68DX3
TVPGVPPLGVSGGES	GON4L	1051	Q3T8J9
LTPPSGEGVSGPVTE	MAST2	961	Q6P0Q8
GPAATTVLQGVTLPP	BICRA	576	Q9NZM4
TSPTEEGGVLTLPPV	FMN2	746	Q9NZ56
GTEPFVTGVRGQVPP	SEC24C	341	P53992
PGLGLSTPVPVTEQG	PERM1	251	Q5SV97
DVVITIPLPSGVGAP	ARCN1	406	P48444
IPLPSGVGAPVIGEI	ARCN1	411	P48444
PGPGPGATATVTVLV	CDH16	541	O75309
GGGGTLVVPIPVPTL	LRCH2	41	Q5VUJ6
LPVPGTGETPTLGTL	HMG20B	266	Q9P0W2
SGISTPPDVLSVGPE	PLIN4	1076	Q96Q06
VSIPTGKGELGSEPP	TSGA10IP	181	Q3SY00
LTPLPEQEGPTVGTV	RAPGEF4	751	Q8WZA2
GPVRLVVLGPTSGSP	THAP8	126	Q8NA92
EPIQPISVIPGSGGE	TAB3	481	Q8N5C8
GLGLTTVPPDVPAAT	LRTM2	56	Q8N967
PGGPVETLSPETVSG	RETREG2	426	Q8NC44
PCPPLVGTSAGVVLV	SLC52A2	361	Q9HAB3
TAISVPEGGLPVAPS	SIX5	591	Q8N196
ALEGQTPVTTVPPGA	MUTYH	456	Q9UIF7
SGPIIIRTPTVGPNG	SP1	446	P08047
IPTGVYGPLPEGTVG	ERVK-9	686	P63128
VSLVGGPSVPTSPVG	SCN1A	651	P35498
IDTEAPGLPGVPVTT	C15orf39	621	Q6ZRI6
IFLPPITSAGGPVTV	TRAK2	641	O60296
VSPQVPPVSLVSGGL	USP43	1016	Q70EL4
VDPGEGRPPITGVIS	TICRR	396	Q7Z2Z1
ILSPCPPLVGTTAGV	SLC52A1	361	Q9NWF4
GELTISGLPPTVTVP	PAPLN	1131	O95428
SGLPPTVTVPEGDTA	PAPLN	1136	O95428
RTHGVGGVPLPTTPV	ZNF574	411	Q6ZN55
TVGGSLSSVLGPPVP	SAP130	766	Q9H0E3
GSVHSGSVPGLPPVE	TSSC4	286	Q9Y5U2
GSVPGLPPVETVGFH	TSSC4	291	Q9Y5U2
IGPGVPVPVSGESTS	KRT10-AS1	141	Q8N816
GPVVVVAPGPPVTTA	TBC1D10B	31	Q4KMP7
PVIPVPSKGSFGGVL	SKOR2	381	Q2VWA4
GVVTSGGLPIPPVSE	WNK1	1391	Q9H4A3
VLPVGTELPAGTLPS	WNK1	1761	Q9H4A3
LGEAAPGTPTPVSVA	UPK3B	61	Q9BT76
AAGVPVVPGTDAPIT	PC	161	P11498
TALELPGQPSVTGVP	SON	556	P18583
GTTKIGGPAPSPSVL	TYRO3	176	Q06418
PSTCIVTLVPGIPTG	ZNF638	1276	Q14966
GPGAPVTTTEPVTVQ	MYBPC3	951	Q14896