Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopeptidase activity	PCSK1 TINAG RHBDF2 PITRM1 ADAM23 CTSC PCSK6 CASP1 CELA1 USP48	1.59e-05	430	86	10	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	PCSK1 TINAG RHBDF2 PITRM1 ADAM23 NPEPPS CTSC PCSK6 CASP1 CELA1 USPL1 USP48	2.30e-05	654	86	12	GO:0008233
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups	CYP2C8 CYP2C9 XDH	3.38e-05	15	86	3	GO:0016725
GeneOntologyMolecularFunction	translation elongation factor activity	EEF1A1 EEF1A1P5 EEF1A2	8.34e-05	20	86	3	GO:0003746
GeneOntologyMolecularFunction	hyaluronan synthase activity	HAS2 HAS3	1.09e-04	4	86	2	GO:0050501
GeneOntologyMolecularFunction	glucokinase activity	HK1 HK2	1.82e-04	5	86	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK1 HK2	1.82e-04	5	86	2	GO:0004396
GeneOntologyMolecularFunction	ATP:ADP antiporter activity	SLC25A5 SLC25A6	1.82e-04	5	86	2	GO:0005471
GeneOntologyMolecularFunction	fructokinase activity	HK1 HK2	1.82e-04	5	86	2	GO:0008865
GeneOntologyMolecularFunction	alcohol dehydrogenase (NAD+) activity	ADH5 ADH6 ADH1A	1.87e-04	26	86	3	GO:0004022
GeneOntologyMolecularFunction	alcohol dehydrogenase [NAD(P)+] activity	ADH5 ADH6 ADH1A	2.88e-04	30	86	3	GO:0018455
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	CYP2C8 CYP2C9	5.05e-04	8	86	2	GO:0033695
GeneOntologyMolecularFunction	caffeine oxidase activity	CYP2C8 CYP2C9	5.05e-04	8	86	2	GO:0034875
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	TINAG CTSC CASP1 USP48	5.20e-04	86	86	4	GO:0004197
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC25A5 SLC25A6 SLC37A2	6.30e-04	39	86	3	GO:0015605
GeneOntologyMolecularFunction	TAP complex binding	TAPBPL HLA-E	6.47e-04	9	86	2	GO:0062061
GeneOntologyMolecularFunction	ADP transmembrane transporter activity	SLC25A5 SLC25A6	9.83e-04	11	86	2	GO:0015217
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP2C8 CYP2C9	9.83e-04	11	86	2	GO:0101020
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MFAP4 TINAG HMCN2 CRELD2 CHI3L1	1.32e-03	188	86	5	GO:0005201
GeneOntologyMolecularFunction	serine-type endopeptidase activity	PCSK1 RHBDF2 CTSC PCSK6 CELA1	1.38e-03	190	86	5	GO:0004252
GeneOntologyMolecularFunction	cysteine-type peptidase activity	TINAG CTSC CASP1 USPL1 USP48	1.45e-03	192	86	5	GO:0008234
GeneOntologyMolecularFunction	D-glucose binding	HK1 HK2	1.61e-03	14	86	2	GO:0005536
GeneOntologyMolecularFunction	ATP transmembrane transporter activity	SLC25A5 SLC25A6	1.61e-03	14	86	2	GO:0005347
GeneOntologyMolecularFunction	retinoic acid 4-hydroxylase activity	CYP2C8 CYP2C9	1.61e-03	14	86	2	GO:0008401
GeneOntologyMolecularFunction	transition metal ion binding	ADH5 ADH6 PARP1 CYP2C8 CYP2C9 PITRM1 NPEPPS ENPP2 XDH TRIM50 KDM1B F8 ADH1A	1.67e-03	1189	86	13	GO:0046914
GeneOntologyMolecularFunction	serine-type peptidase activity	PCSK1 RHBDF2 CTSC PCSK6 CELA1	2.01e-03	207	86	5	GO:0008236
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC25A5 SLC25A6 SLC37A2	2.11e-03	59	86	3	GO:1901505
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	ADH5 ADH6 KCNAB2 ADH1A	2.22e-03	127	86	4	GO:0016616
GeneOntologyMolecularFunction	carbohydrate binding	HK1 HK2 STBD1 ENPP2 FAM3A CHI3L1	2.22e-03	310	86	6	GO:0030246
GeneOntologyMolecularFunction	serine hydrolase activity	PCSK1 RHBDF2 CTSC PCSK6 CELA1	2.23e-03	212	86	5	GO:0017171
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH-OH group of donors	ADH5 ADH6 KCNAB2 ADH1A	2.99e-03	138	86	4	GO:0016614
GeneOntologyMolecularFunction	carbohydrate kinase activity	HK1 HK2	3.65e-03	21	86	2	GO:0019200
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC25A5 SLC25A6	4.37e-03	23	86	2	GO:0005346
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP2C8 CYP2C9	4.76e-03	24	86	2	GO:0008392
GeneOntologyMolecularFunction	all-trans-retinol dehydrogenase (NAD+) activity	ADH6 ADH1A	4.76e-03	24	86	2	GO:0004745
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC25A5 SLC25A6	5.57e-03	26	86	2	GO:0000295
GeneOntologyMolecularFunction	oxidoreductase activity	ADH5 ADH6 CYP2C8 CYP2C9 KCNAB2 XDH KDM1B F8 ADH1A	5.66e-03	766	86	9	GO:0016491
GeneOntologyMolecularFunction	translation factor activity, RNA binding	EEF1A1 EEF1A1P5 EEF1A2	5.91e-03	85	86	3	GO:0008135
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP2C8 CYP2C9	6.00e-03	27	86	2	GO:0008391
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	RAF1 MAP3K7	6.00e-03	27	86	2	GO:0004709
GeneOntologyMolecularFunction	SMAD binding	PARP1 HIPK2 SMAD7	6.10e-03	86	86	3	GO:0046332
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYP2C8 CYP2C9 STBD1 PNPLA6 LCTL RHBDF2 OTOF TAPBPL SYNE1 PPM1L HLA-E TOR1A SLC37A2 B3GAT1 HAS2 MAP3K7 MTDH	2.84e-05	1327	87	17	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYP2C8 CYP2C9 STBD1 PNPLA6 LCTL RHBDF2 OTOF TAPBPL PPM1L HLA-E TOR1A SLC37A2 B3GAT1 HAS2 MAP3K7 MTDH	7.65e-05	1293	87	16	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYP2C8 CYP2C9 STBD1 PNPLA6 LCTL RHBDF2 OTOF TAPBPL PPM1L HLA-E TOR1A SLC37A2 B3GAT1 HAS2 MAP3K7 MTDH	8.08e-05	1299	87	16	GO:0098827
GeneOntologyCellularComponent	eukaryotic translation elongation factor 1 complex	EEF1A1 EEF1A2	1.02e-04	4	87	2	GO:0005853
Domain	ADH_Zn_CS	ADH5 ADH6 ADH1A	5.01e-06	8	85	3	IPR002328
Domain	ADH_ZINC	ADH5 ADH6 ADH1A	5.01e-06	8	85	3	PS00059
Domain	Transl_elong_EF1A_euk/arc	EEF1A1 EEF1A2	2.05e-05	2	85	2	IPR004539
Domain	ADH_N	ADH5 ADH6 ADH1A	4.88e-05	16	85	3	PF08240
Domain	ADH_N	ADH5 ADH6 ADH1A	4.88e-05	16	85	3	IPR013154
Domain	HAS/NodC	HAS2 HAS3	6.12e-05	3	85	2	IPR026107
Domain	-	ADH5 ADH6 ADH1A	7.07e-05	18	85	3	3.90.180.10
Domain	ADH_zinc_N	ADH5 ADH6 ADH1A	8.36e-05	19	85	3	PF00107
Domain	ADH_SF_Zn-type	ADH5 ADH6 ADH1A	8.36e-05	19	85	3	IPR002085
Domain	ADH_C	ADH5 ADH6 ADH1A	8.36e-05	19	85	3	IPR013149
Domain	GroES-like	ADH5 ADH6 ADH1A	1.72e-04	24	85	3	IPR011032
Domain	Hexokinase_C	HK1 HK2	2.03e-04	5	85	2	IPR022673
Domain	Hexokinase_N	HK1 HK2	2.03e-04	5	85	2	IPR022672
Domain	Hexokinase_1	HK1 HK2	2.03e-04	5	85	2	PF00349
Domain	Hexokinase_2	HK1 HK2	2.03e-04	5	85	2	PF03727
Domain	HEXOKINASE_2	HK1 HK2	2.03e-04	5	85	2	PS51748
Domain	Hexokinase_BS	HK1 HK2	2.03e-04	5	85	2	IPR019807
Domain	HEXOKINASE_1	HK1 HK2	2.03e-04	5	85	2	PS00378
Domain	Transl_B-barrel	RPL3L EEF1A1 EEF1A2	2.46e-04	27	85	3	IPR009000
Domain	Hexokinase	HK1 HK2	3.03e-04	6	85	2	IPR001312
Domain	Peptidase_S8_Asp-AS	PCSK1 PCSK6	3.03e-04	6	85	2	IPR023827
Domain	PrprotnconvertsP	PCSK1 PCSK6	4.24e-04	7	85	2	IPR002884
Domain	P_proprotein	PCSK1 PCSK6	4.24e-04	7	85	2	PF01483
Domain	S8_pro-domain	PCSK1 PCSK6	4.24e-04	7	85	2	IPR032815
Domain	-	PCSK1 PCSK6	4.24e-04	7	85	2	3.30.70.850
Domain	S8_pro-domain	PCSK1 PCSK6	4.24e-04	7	85	2	PF16470
Domain	Transl_elong_EFTu/EF1A_C	EEF1A1 EEF1A2	5.63e-04	8	85	2	IPR004160
Domain	Somatomedin_B	TINAG ENPP2	5.63e-04	8	85	2	PF01033
Domain	GTP_EFTU_D3	EEF1A1 EEF1A2	5.63e-04	8	85	2	PF03143
Domain	Peptidase_S8_His-AS	PCSK1 PCSK6	7.22e-04	9	85	2	IPR022398
Domain	SO	TINAG ENPP2	7.22e-04	9	85	2	SM00201
Domain	G_TR_CS	EEF1A1 EEF1A2	7.22e-04	9	85	2	IPR031157
Domain	Peptidase_S8_Ser-AS	PCSK1 PCSK6	7.22e-04	9	85	2	IPR023828
Domain	Somatomedin_B_dom	TINAG ENPP2	9.00e-04	10	85	2	IPR001212
Domain	Pept_asp_AS	TINAG CTSC	9.00e-04	10	85	2	IPR025661
Domain	Peptidase_S8_subtilisin-rel	PCSK1 PCSK6	9.00e-04	10	85	2	IPR015500
Domain	SMB_1	TINAG ENPP2	9.00e-04	10	85	2	PS00524
Domain	SMB_2	TINAG ENPP2	9.00e-04	10	85	2	PS50958
Domain	Transl_elong_EF1A/Init_IF2_C	EEF1A1 EEF1A2	9.00e-04	10	85	2	IPR009001
Domain	SUBTILASE_ASP	PCSK1 PCSK6	9.00e-04	10	85	2	PS00136
Domain	SUBTILASE_HIS	PCSK1 PCSK6	9.00e-04	10	85	2	PS00137
Domain	SUBTILASE_SER	PCSK1 PCSK6	9.00e-04	10	85	2	PS00138
Domain	-	PCSK1 PCSK6	1.10e-03	11	85	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK1 PCSK6	1.10e-03	11	85	2	IPR000209
Domain	Peptidase_S8	PCSK1 PCSK6	1.10e-03	11	85	2	PF00082
Domain	Mit_uncoupling	SLC25A5 SLC25A6	1.31e-03	12	85	2	IPR002030
Domain	G_TR_1	EEF1A1 EEF1A2	1.55e-03	13	85	2	PS00301
Domain	Pept_C1	TINAG CTSC	1.55e-03	13	85	2	SM00645
Domain	Peptidase_C1A_C	TINAG CTSC	1.55e-03	13	85	2	IPR000668
Domain	Peptidase_C1	TINAG CTSC	1.55e-03	13	85	2	PF00112
Domain	Peptidase_C1A	TINAG CTSC	1.55e-03	13	85	2	IPR013128
Domain	PKS_ER	ADH6 ADH1A	2.36e-03	16	85	2	SM00829
Domain	PKS_ER	ADH6 ADH1A	2.36e-03	16	85	2	IPR020843
Domain	Propept_inh	PCSK1 PCSK6	2.66e-03	17	85	2	IPR009020
Domain	EFTu-like_2	EEF1A1 EEF1A2	2.99e-03	18	85	2	IPR004161
Domain	Furin_repeat	PCSK6 CRELD2	2.99e-03	18	85	2	IPR006212
Domain	FU	PCSK6 CRELD2	2.99e-03	18	85	2	SM00261
Domain	GTP_EFTU_D2	EEF1A1 EEF1A2	2.99e-03	18	85	2	PF03144
Domain	G_TR_2	EEF1A1 EEF1A2	2.99e-03	18	85	2	PS51722
Domain	TF_GTP-bd_dom	EEF1A1 EEF1A2	3.33e-03	19	85	2	IPR000795
Domain	-	PCSK1 PCSK6 F8	4.50e-03	73	85	3	2.60.120.260
Pathway	KEGG_GLYCOLYSIS_GLUCONEOGENESIS	ADH5 ADH6 HK1 HK2 ADH1A	1.67e-05	62	73	5	M11521
Pathway	KEGG_RETINOL_METABOLISM	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	1.95e-05	64	73	5	M9488
Pathway	REACTOME_ETHANOL_OXIDATION	ADH5 ADH6 ADH1A	2.83e-05	12	73	3	M14663
Pathway	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	3.02e-05	70	73	5	M16794
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	3.46e-05	72	73	5	M9257
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	2.00e-04	104	73	5	M738
Pathway	REACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT	HAS2 HAS3	2.62e-04	5	73	2	M27144
Pathway	REACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT	HAS2 HAS3	2.62e-04	5	73	2	MM14865
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	HK1 HK2	3.91e-04	6	73	2	M47654
Pathway	REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS	CYP2C8 CYP2C9	3.91e-04	6	73	2	M27909
Pubmed	TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.	SLC25A5 SLC25A6 ENAH MAP3K7 SMAD7	1.33e-08	30	89	5	23973329
Pubmed	Merging protein, gene and genomic data: the evolution of the MDR-ADH family.	ADH5 ADH6 ADH1A	3.22e-07	6	89	3	16121213
Pubmed	Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.	ADH5 ADH6 ADH1A	3.22e-07	6	89	3	17185388
Pubmed	Viral immune modulators perturb the human molecular network by common and unique strategies.	SLC25A5 SLC25A6 SYNE1 EEF1A1 EEF1A1P5 EEF1A2	5.60e-07	116	89	6	22810585
Pubmed	Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.	ADH5 ADH6 ADH1A	5.63e-07	7	89	3	16685648
Pubmed	Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.	ADH5 ADH6 ADH1A	5.63e-07	7	89	3	23456092
Pubmed	Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.	ADH5 ADH6 ADH1A	5.63e-07	7	89	3	23468174
Pubmed	Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes.	ADH5 ADH6 ADH1A	5.63e-07	7	89	3	11784316
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	ADH6 CYP2C8 CYP2C9 PNPLA6 B3GAT1 ABCG8 ADH1A	6.82e-07	193	89	7	19343046
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	PARP1 PITRM1 SLC25A5 NPEPPS CTSC KCNAB2 XDH EEF1A1	2.97e-06	344	89	8	30333137
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	RAF1 RBM25 SLC25A5 SLC25A6 EEF1A1 EEF1A1P5 EEF1A2	4.45e-06	256	89	7	24189400
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	PARP1 RBM25 SLC25A5 SLC25A6 WDR6 ARID2 MTDH EEF1A1 EEF1A2	4.46e-06	486	89	9	30940648
Pubmed	Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2.	SLC25A5 SLC25A6 EEF1A1 EEF1A1P5 EEF1A2	4.49e-06	94	89	5	36584595
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	RAF1 PARP1 SLC25A5 NPEPPS TNRC6B EEF1A1	4.52e-06	166	89	6	35687106
Pubmed	Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform.	CYP2C8 CYP2C9	6.48e-06	2	89	2	7574697
Pubmed	C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A.	RAF1 EEF1A1	6.48e-06	2	89	2	17332776
Pubmed	Individuals with CYP2C8 and CYP2C9 reduced metabolism haplotypes self-adjusted ibuprofen dose in the Coriell Personalized Medicine Collaborative.	CYP2C8 CYP2C9	6.48e-06	2	89	2	30562214
Pubmed	Effect of gender and CYP2C9 and CYP2C8 polymorphisms on the pharmacokinetics of ibuprofen enantiomers.	CYP2C8 CYP2C9	6.48e-06	2	89	2	26122864
Pubmed	Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms.	CYP2C8 CYP2C9	6.48e-06	2	89	2	12435384
Pubmed	Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers.	CYP2C8 CYP2C9	6.48e-06	2	89	2	18694831
Pubmed	eEF1A demonstrates paralog specific effects on HIV-1 reverse transcription efficiency.	EEF1A1 EEF1A2	6.48e-06	2	89	2	30782564
Pubmed	Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.	ADH5 ADH1A	6.48e-06	2	89	2	29248712
Pubmed	Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance.	CYP2C8 CYP2C9	6.48e-06	2	89	2	16372821
Pubmed	Changes in the expression of the human adenine nucleotide translocase isoforms condition cellular metabolic/proliferative status.	SLC25A5 SLC25A6	6.48e-06	2	89	2	26842067
Pubmed	Relationship between CYP2C8 genotypes and diclofenac 5-hydroxylation in healthy Spanish volunteers.	CYP2C8 CYP2C9	6.48e-06	2	89	2	18548238
Pubmed	Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction.	CYP2C8 CYP2C9	6.48e-06	2	89	2	14646690
Pubmed	Pharmacokinetic studies of enantiomers of ibuprofen and its chiral metabolites in humans with different variants of genes coding CYP2C8 and CYP2C9 isoenzymes.	CYP2C8 CYP2C9	6.48e-06	2	89	2	19480553
Pubmed	Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily.	CYP2C8 CYP2C9	6.48e-06	2	89	2	15766564
Pubmed	Renal cortical hexokinase and pentose phosphate pathway activation through the EGFR/Akt signaling pathway in endotoxin-induced acute kidney injury.	HK1 HK2	6.48e-06	2	89	2	24990892
Pubmed	Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.	EEF1A1 EEF1A2	6.48e-06	2	89	2	35741005
Pubmed	Impact of CYP2C8 and 2C9 polymorphisms on coronary artery disease and myocardial infarction in the LURIC cohort.	CYP2C8 CYP2C9	6.48e-06	2	89	2	21047199
Pubmed	Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals.	CYP2C8 CYP2C9	6.48e-06	2	89	2	16646575
Pubmed	cDNA and amino acid sequences of two members of the human P450IIC gene subfamily.	CYP2C8 CYP2C9	6.48e-06	2	89	2	3697070
Pubmed	Global variation in CYP2C8-CYP2C9 functional haplotypes.	CYP2C8 CYP2C9	6.48e-06	2	89	2	19381162
Pubmed	The effect of standard chow and reduced hexokinase II on growth, cardiac and skeletal muscle hexokinase and low-flow cardiac ischaemia-reperfusion injury.	HK1 HK2	6.48e-06	2	89	2	21504994
Pubmed	The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders.	EEF1A1 EEF1A2	6.48e-06	2	89	2	30370994
Pubmed	CYP2C8 and CYP2C9 polymorphisms in relation to tumour characteristics and early breast cancer related events among 652 breast cancer patients.	CYP2C8 CYP2C9	6.48e-06	2	89	2	19935798
Pubmed	The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.	HAS2 HAS3	6.48e-06	2	89	2	20507985
Pubmed	New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A.	EEF1A1 EEF1A2	6.48e-06	2	89	2	26212729
Pubmed	Role of xenobiotic metabolism enzyme gene polymorphism in the formation of chemotherapy resistance in patients with chronic lymphoproliferative diseases.	CYP2C8 CYP2C9	6.48e-06	2	89	2	24288737
Pubmed	Distribution of CYP2C8 and CYP2C9 amino acid substitution alleles in South Indian diabetes patients: A genotypic and computational protein phenotype study.	CYP2C8 CYP2C9	6.48e-06	2	89	2	28686288
Pubmed	Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants?	CYP2C8 CYP2C9	6.48e-06	2	89	2	20808793
Pubmed	The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade.	EEF1A1 EEF1A2	6.48e-06	2	89	2	17825975
Pubmed	The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.	CYP2C8 CYP2C9	6.48e-06	2	89	2	15606441
Pubmed	Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression.	EEF1A1 EEF1A2	6.48e-06	2	89	2	22095224
Pubmed	Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.	EEF1A1 EEF1A2	6.48e-06	2	89	2	38220433
Pubmed	Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.	EEF1A1 EEF1A2	6.48e-06	2	89	2	19636410
Pubmed	The clinically relevant CYP2C83 and CYP2C92 haplotype is inherited from Neandertals.	CYP2C8 CYP2C9	6.48e-06	2	89	2	35780191
Pubmed	Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding.	CYP2C8 CYP2C9	6.48e-06	2	89	2	18216720
Pubmed	Genetic variance in CYP2C8 and increased risk of myocardial infarction.	CYP2C8 CYP2C9	6.48e-06	2	89	2	20436375
Pubmed	Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1.	CYP2C8 CYP2C9	6.48e-06	2	89	2	7841444
Pubmed	Changes at the CYP2C locus and disruption of CYP2C8/9 linkage disequilibrium in patients with essential tremor.	CYP2C8 CYP2C9	6.48e-06	2	89	2	17627038
Pubmed	Are SMAD7 rs4939827 and CHI3L1 rs4950928 polymorphisms associated with colorectal cancer in Egyptian patients?	CHI3L1 SMAD7	6.48e-06	2	89	2	26779637
Pubmed	A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity.	ADH6 ADH1A	6.48e-06	2	89	2	12050823
Pubmed	Pharmacogenetic relevance of the CYP2C9*3 allele in a tenoxicam bioequivalence study performed on Spaniards.	CYP2C8 CYP2C9	6.48e-06	2	89	2	18992346
Pubmed	Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.	EEF1A1 EEF1A2	6.48e-06	2	89	2	7945283
Pubmed	Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.	EEF1A1 EEF1A2	6.48e-06	2	89	2	32347192
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	PARP1 RBM25 SLC25A5 SLC25A6 WDR6 NPEPPS MAP3K7 EEF1A1	6.53e-06	383	89	8	29331416
Pubmed	Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3.	EEF1A1 EEF1A1P5 EEF1A2	7.21e-06	15	89	3	8812466
Pubmed	Genetic loci that control the angiogenic response to basic fibroblast growth factor.	ENPP2 HAS2 MAP3K7	8.86e-06	16	89	3	15226265
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	PARP1 SLC25A5 SLC25A6 WDR6 NPEPPS EEF1A1 EEF1A2	9.58e-06	288	89	7	31501420
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	KCNAB2 RPL3L EEF1A1 EEF1A1P5 EEF1A2	1.26e-05	116	89	5	30652415
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	PARP1 SLC25A5 SLC25A6 ENAH TNRC6B SV2C SORBS1 EEF1A1 EEF1A2	1.34e-05	558	89	9	35063084
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	RAF1 PARP1 SLC25A5 SLC25A6 WDR6 NPEPPS HLA-E TNRC6B MTDH EEF1A1	1.68e-05	725	89	10	27025967
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	PARP1 HK1 SLC25A5 SLC25A6 EEF1A1P5 EEF1A2	1.73e-05	210	89	6	26217791
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	XIRP2 SYNE1 EEF1A1	1.79e-05	20	89	3	21689717
Pubmed	Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.	SLC25A5 SLC25A6 MTDH EEF1A1 EEF1A1P5	1.80e-05	125	89	5	36030824
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RAF1 PARP1 HK1 HK2 SLC25A5 SLC25A6 WDR6 NPEPPS HLA-E TNRC6B EEF1A1 EEF1A1P5 EEF1A2	1.85e-05	1257	89	13	37317656
Pubmed	Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells.	HAS2 HAS3	1.94e-05	3	89	2	16564133
Pubmed	Mammalian hyaluronan synthases: investigation of functional relationships in vivo.	HAS2 HAS3	1.94e-05	3	89	2	10093717
Pubmed	[Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods].	HK1 HK2	1.94e-05	3	89	2	26855992
Pubmed	Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress.	HK1 HK2	1.94e-05	3	89	2	21430642
Pubmed	The human CYP2C locus: a prototype for intergenic and exon repetition splicing events.	CYP2C8 CYP2C9	1.94e-05	3	89	2	10704292
Pubmed	Hyaluronan Regulates Eyelid and Meibomian Gland Morphogenesis.	HAS2 HAS3	1.94e-05	3	89	2	30046813
Pubmed	Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells.	PARP1 EEF1A1	1.94e-05	3	89	2	17177976
Pubmed	Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.	HAS2 HAS3	1.94e-05	3	89	2	25795779
Pubmed	Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.	HAS2 HAS3	1.94e-05	3	89	2	23303191
Pubmed	Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase.	CYP2C8 CYP2C9	1.94e-05	3	89	2	3196692
Pubmed	Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro.	EEF1A1 EEF1A2	1.94e-05	3	89	2	19559761
Pubmed	Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.	HAS2 HAS3	1.94e-05	3	89	2	22654110
Pubmed	Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells.	HAS2 HAS3	1.94e-05	3	89	2	11790779
Pubmed	Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.	HAS2 HAS3	1.94e-05	3	89	2	23979132
Pubmed	CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project.	CYP2C8 CYP2C9	1.94e-05	3	89	2	35134542
Pubmed	The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.	SLC25A5 SLC25A6	1.94e-05	3	89	2	12450408
Pubmed	Effect of Increased IL-1β on Expression of HK in Alzheimer's Disease.	HK1 HK2	1.94e-05	3	89	2	33525649
Pubmed	Distribution of CYP2C polymorphisms in an Amerindian population of Brazil.	CYP2C8 CYP2C9	1.94e-05	3	89	2	21977947
Pubmed	Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity.	HK1 HK2	1.94e-05	3	89	2	19049977
Pubmed	DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.	SLC25A5 SLC25A6	1.94e-05	3	89	2	2541251
Pubmed	Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns.	HAS2 HAS3	1.94e-05	3	89	2	15765504
Pubmed	Hyaluronan Modulates the Biomechanical Properties of the Cornea.	HAS2 HAS3	1.94e-05	3	89	2	36478198
Pubmed	Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.	SLC25A5 SLC25A6	1.94e-05	3	89	2	2829183
Pubmed	Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.	HAS2 HAS3	1.94e-05	3	89	2	30897620
Pubmed	Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.	HK2 XDH	1.94e-05	3	89	2	29414774
Pubmed	Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan.	HK1 CASP1	1.94e-05	3	89	2	27374331
Pubmed	Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.	EEF1A1 EEF1A2	1.94e-05	3	89	2	37429391
Pubmed	A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to suppress host cell apoptosis.	HK1 HK2	1.94e-05	3	89	2	20347420
Pubmed	In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity.	HAS2 HAS3	1.94e-05	3	89	2	10617644
Pubmed	c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis.	HK1 HK2	1.94e-05	3	89	2	28054552
Pubmed	Time-dependent expression pattern of cytochrome P450 epoxygenases and soluble epoxide hydrolase in normal human placenta.	CYP2C8 CYP2C9	1.94e-05	3	89	2	29908721
Pubmed	Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses.	CASP1 CHI3L1	1.94e-05	3	89	2	22817986
Interaction	YAP1 interactions	BPTF PARP1 RBM25 TULP4 SLC25A5 SLC25A6 WDR6 NPEPPS HECW2 ARID2 CTSC ARFGAP1 ENAH TNRC6B MAP3K7 EEF1A1 SMAD7 EEF1A1P5 EEF1A2	1.63e-07	1095	87	19	int:YAP1
Interaction	FER1L6 interactions	EEF1A1 EEF1A1P5 EEF1A2	2.69e-06	7	87	3	int:FER1L6
Cytoband	4q23	ADH5 ADH6 ADH1A	7.84e-06	20	89	3	4q23
Cytoband	Ensembl 112 genes in cytogenetic band chr4q23	ADH5 ADH6 ADH1A	5.22e-05	37	89	3	chr4q23
Cytoband	2p23.1	OTOF XDH	1.03e-04	8	89	2	2p23.1
Cytoband	10q23.33	CYP2C8 SORBS1	9.16e-04	23	89	2	10q23.33
GeneFamily	Alcohol dehydrogenases	ADH5 ADH6 ADH1A	2.34e-06	8	64	3	397
GeneFamily	Glycosyltransferase family 2	HAS2 HAS3	1.83e-04	6	64	2	428
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK1 PCSK6	4.37e-04	9	64	2	973
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	RAF1 MAP3K7	3.24e-03	24	64	2	654
Coexpression	CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN	ADH6 CYP2C8 CYP2C9 F8 ABCG8 ADH1A	3.39e-05	179	89	6	M16932
Coexpression	GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN	HK1 HK2 RHBDF2 TAPBPL HLA-E CASP1	6.11e-05	199	89	6	M9595
Coexpression	GSE7852_LN_VS_THYMUS_TCONV_UP	PNPLA6 HLA-E CASP1 XDH SLC37A2 MAP3K7	6.11e-05	199	89	6	M5745
Coexpression	GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN	HK1 STBD1 TULP4 WDR6 HLA-E F8	6.29e-05	200	89	6	M9688
Coexpression	GSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_UP	CIITA HECW2 PCSK6 TTL CRELD2 F8	6.29e-05	200	89	6	M6785
Coexpression	GSE7852_TREG_VS_TCONV_FAT_UP	PCSK1 TULP4 PPM1L ACSF3 SLC37A2 SORBS1	6.29e-05	200	89	6	M5733
Coexpression	WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP	CTSC HLA-E CASP1 CELA1	6.75e-05	64	89	4	M1887
Coexpression	RUAN_RESPONSE_TO_TROGLITAZONE_UP	HIPK3 HIPK2 SORBS1	7.27e-05	24	89	3	M1504
Coexpression	MA_RAT_AGING_UP	HK2 HLA-E XDH CHI3L1 EEF1A1	7.40e-05	127	89	5	MM16096
Coexpression	NAKAJIMA_EOSINOPHIL	PNPLA6 SYNE1 SMAD7	8.25e-05	25	89	3	M8344
Coexpression	RUAN_RESPONSE_TO_TROGLITAZONE_UP	HIPK3 HIPK2 SORBS1	8.25e-05	25	89	3	MM1164
ToppCell	E18.5\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TINAG STBD1 SLC25A5 CTSC CELA1 CHI3L1 EEF1A1	1.10e-07	190	89	7	fe9678be25e29a09c0b9ac59da4ee3a29f22dde1
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HECW2 SYNE1 HLA-E HIPK2 SORBS1 SH3RF3 F8	1.27e-07	194	89	7	660535b492445063d965095a50e1e299ce04c50a
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 ENAH KIAA1755 CHI3L1 HAS2 EEF1A1	1.51e-07	199	89	7	b65fbfed4a9938820cf900afd350b4ecb789b7b3
ToppCell	RV\|World / Chamber and Cluster_Paper	XIRP2 ADAM23 PPM1L TNRC6B SORBS1 RPL3L	1.72e-06	181	89	6	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HK2 ADAM23 CTSC ENAH HAS2 SH3RF3	2.08e-06	187	89	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD16\|Liver / Manually curated celltypes from each tissue	SYNE1 CTSC PPM1L HLA-E HIPK2 B3GAT1	2.72e-06	196	89	6	e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 EML6 ENAH KIAA1755 SORBS1 SH3RF3	2.81e-06	197	89	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	T_cells-CTLs\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	RHBDF2 OTOF SYNE1 CTSC KIF19 B3GAT1	2.81e-06	197	89	6	28117cf300e169182571fbad0de1681a484a435a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 EML6 ENAH KIAA1755 SORBS1 SH3RF3	2.81e-06	197	89	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	10x5'-Liver-Lymphocytic_T_CD8-Tem/emra_CD8\|Liver / Manually curated celltypes from each tissue	SYNE1 KIF19 HLA-E B3GAT1 EEF1A1 SMAD7	2.89e-06	198	89	6	2fc2a4638c458ae793ac090a29d27b75fc9e6af6
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 ADAM23 SV2C HAS2 EEF1A1	2.89e-06	198	89	6	d9d3520705a1142083782f077a0c5604d3ea99af
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SYNE1 PPM1L HLA-E HIPK2 B3GAT1 SMAD7	2.97e-06	199	89	6	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ADH5 PCSK1 MFAP4 CHI3L1 HAS2 EEF1A1	2.97e-06	199	89	6	eb5971660dff356721a004f821d52a5b7a33c951
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SYNE1 PPM1L HLA-E HIPK2 B3GAT1 SMAD7	2.97e-06	199	89	6	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	Bronchial_Biopsy-Epithelial-Basal_2\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC25A5 SLC25A6 CTSC CHI3L1 HAS3 EEF1A1	3.06e-06	200	89	6	99997c447f2b59324fe69c17593db72d972c0cc4
ToppCell	Bronchial_Biopsy-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC25A5 SLC25A6 CTSC CHI3L1 HAS3 EEF1A1	3.06e-06	200	89	6	5ed450e65edff713ad5feba4f6c46209bf471f6e
ToppCell	Paneth_cell\|World / shred on cell type and cluster	PCSK1 KIF19 KIAA1755 TRIM50 SH3RF3	1.74e-05	160	89	5	d787b7cdb8c3f677ac9c4934a5df9cc194df3987
ToppCell	C_07\|World / shred on cell type and cluster	PCSK1 KIF19 KIAA1755 TRIM50 SH3RF3	1.74e-05	160	89	5	b7c5a8a1c85da92e1945721b6887b32fad7b76b8
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MFAP4 SH3RF1 HAS2 USP48 ADH1A	2.27e-05	169	89	5	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADH5 MFAP4 CHI3L1 HAS2 EEF1A1	2.40e-05	171	89	5	b6b90fcd9e9e379cad8bb0506f7ec7823861e313
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	HECW2 SYNE1 HLA-E SORBS1 SH3RF3	2.40e-05	171	89	5	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADH5 MFAP4 CHI3L1 EEF1A1 ADH1A	2.40e-05	171	89	5	59d79c3e36a4930af42ebc96f05570641b9fb864
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT2\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TINAG HK2 CTSC CELA1 CHI3L1	2.54e-05	173	89	5	f6e36ea98a9c669ff393d141455aaecef083f738
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	2.54e-05	173	89	5	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	wk_20-22-Epithelial-PNS\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LCTL KIAA1755 B3GAT1 GRIK3 SORBS1	2.54e-05	173	89	5	17b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	ADH6 CYP2C8 CYP2C9 ABCG8 ADH1A	2.61e-05	174	89	5	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	CYP2C8 CYP2C9 PCSK6 ABCG8 ADH1A	2.61e-05	174	89	5	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CIITA HECW2 HLA-E HAS2 F8	2.68e-05	175	89	5	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LCTL KIAA1755 B3GAT1 GRIK3 SORBS1	2.75e-05	176	89	5	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TNK1 MFAP4 PCSK6 KIAA1755 HAS2	2.83e-05	177	89	5	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ENAH CELA1 F8 CRB1	2.91e-05	178	89	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	wk_08-11-Epithelial-PNS-Late_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	OTOF ADAM23 KIAA1755 B3GAT1 GRIK3	2.91e-05	178	89	5	a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK6 HIPK2 SORBS1 SH3RF3 F8	3.07e-05	180	89	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFN1 XIRP2 RPL3L EEF1A2 MYBPC2	3.07e-05	180	89	5	cea62fc006d68c3815c88bf17ec2617d7e41c3d2
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCSK6 KIAA1755 B3GAT1 GRIK3 CRB1	3.15e-05	181	89	5	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNK1 HK2 KIF19 HAS2	3.21e-05	90	89	4	6adc78899a08d48da8ed4618ecf866c9ed9be059
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNK1 HK2 KIF19 HAS2	3.21e-05	90	89	4	a74f8172780adc1410e36e2718412010ee0ebf1f
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNK1 HK2 KIF19 HAS2	3.21e-05	90	89	4	909ad62d175b657d8e541b0981ce8fed0ba7ed6c
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P2\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNK1 HK2 KIF19 HAS2	3.21e-05	90	89	4	936c5078677ec934f3049d8aa5a14d930aa2e6dc
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAM23 PCSK6 KIAA1755 GRIK3 CRB1	3.23e-05	182	89	5	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 XIRP2 RPL3L EEF1A2 MYBPC2	3.32e-05	183	89	5	6f5dbac2748f50105f0f548d189c42ef14287019
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PCSK6 KIAA1755 B3GAT1 GRIK3 CRB1	3.32e-05	183	89	5	f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAM23 SYNE1 TNRC6B EEF1A1 EEF1A1P5	3.68e-05	187	89	5	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	HIPK3 ADAM23 ENPP2 KIF19 ENAH	3.68e-05	187	89	5	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	HECW2 SYNE1 HLA-E SORBS1 SH3RF3	3.77e-05	188	89	5	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	HECW2 SYNE1 HLA-E SORBS1 SH3RF3	3.77e-05	188	89	5	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HK1 SLC25A6 CTSC EFCAB13 SMAD7	3.77e-05	188	89	5	e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	ENPP2 PCSK6 HIPK2 SV2C EEF1A2	3.97e-05	190	89	5	d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 TRIM50 RPL3L EEF1A2 MYBPC2	4.07e-05	191	89	5	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	MFAP4 SLC25A6 KIF19 CRB1 EEF1A1	4.07e-05	191	89	5	48cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 TRIM50 RPL3L EEF1A2 MYBPC2	4.07e-05	191	89	5	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	MFAP4 SLC25A6 KIF19 CRB1 EEF1A1	4.07e-05	191	89	5	e4c1c533771b582e21683dbec6f93a558d865e00
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	BPTF RBM25 WDR6 ARFGAP1 HLA-E	4.17e-05	192	89	5	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HECW2 PCSK6 HLA-E SORBS1 SH3RF3	4.17e-05	192	89	5	7197e401e563441ab94815f7619e032ebef9e586
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 CTSC KIF19 HLA-E B3GAT1	4.27e-05	193	89	5	d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 CTSC KIF19 HLA-E B3GAT1	4.27e-05	193	89	5	c1d9c2436503791350086a503d6b98c5c69f44ae
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	HECW2 PCSK6 HLA-E SORBS1 SH3RF3	4.27e-05	193	89	5	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-DC2\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLC25A5 CIITA SLC25A6 CTSC CASP1	4.38e-05	194	89	5	a0cfc8c1cdc0722db39170e4417615b6e6b85041
ToppCell	BLOOD--(1)_EM_CTLs\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SYNE1 CTSC KIF19 HLA-E B3GAT1	4.38e-05	194	89	5	66583c6cff3814902d6babdea3a2ae962decde65
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	MFAP4 HMCN2 PCSK6 KIAA1755 HAS2	4.38e-05	194	89	5	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 CTSC KIF19 B3GAT1 SMAD7	4.38e-05	194	89	5	ecdfc27d06e363fb23f0309f26ef6404a89f14ec
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SYNE1 CTSC PPM1L HIPK2 B3GAT1	4.38e-05	194	89	5	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	4.49e-05	195	89	5	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-immature_B_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RHBDF2 CIITA HLA-E EEF1A1	4.49e-05	195	89	5	ecaaa3d071e763c40d05d088fbf9e8ca06f78f47
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 ENPP2 RPL3L EEF1A2 MYBPC2	4.49e-05	195	89	5	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	IGFN1 SLC25A5 SLC25A6 MTDH EEF1A1	4.49e-05	195	89	5	7fb5c0911ff09580515d1a1827d7249d6242630c
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP4 CTSC KIAA1755 HAS2 EEF1A1	4.60e-05	196	89	5	a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HECW2 SYNE1 HLA-E SORBS1 SH3RF3	4.60e-05	196	89	5	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	15-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	MFAP4 ENPP2 ENAH HAS2 EEF1A1	4.60e-05	196	89	5	b8d95b5f4780e73d16dcc528e70a5496f0314373
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 CTSC PPM1L B3GAT1 SMAD7	4.60e-05	196	89	5	f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCell	5'-Adult-Appendix\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP4 SYNE1 HLA-E CHI3L1 F8	4.60e-05	196	89	5	a579211ef14f348d0c5a290553150222dfbf1515
ToppCell	10x5'-bone_marrow-Lymphocytic_NK-NK_CD16\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 CTSC PPM1L HLA-E HIPK2	4.60e-05	196	89	5	a3b077e82b1550eb328c84b567b60179001f9a77
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	HECW2 SYNE1 HLA-E SORBS1 SH3RF3	4.60e-05	196	89	5	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	STBD1 SYNE1 SORBS1 CHI3L1 EEF1A1	4.71e-05	197	89	5	fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	MFAP4 ADAM23 ENPP2 KIF19 CHI3L1	4.71e-05	197	89	5	d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 PPM1L HLA-E HIPK2 B3GAT1	4.83e-05	198	89	5	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	4.83e-05	198	89	5	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	4.83e-05	198	89	5	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	4.83e-05	198	89	5	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 CHI3L1 HAS2 EEF1A1	4.83e-05	198	89	5	77c81ec602ab553a544c3d9b1e66181b6f000d12
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	BPTF RBM25 SLC25A6 TNRC6B EEF1A1	4.83e-05	198	89	5	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM23 SYNE1 EML6 PPM1L SORBS1	4.83e-05	198	89	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HECW2 HLA-E SORBS1 SH3RF3 F8	4.83e-05	198	89	5	1d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MFAP4 ENPP2 ENAH KIAA1755 CHI3L1	4.83e-05	198	89	5	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 PPM1L HLA-E HIPK2 B3GAT1	4.83e-05	198	89	5	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE1 HLA-E SH3RF3 F8	4.83e-05	198	89	5	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	wk_08-11-Mesenchymal-Fibroblast-intermediate_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MFAP4 ENPP2 CTSC ENAH EEF1A1	4.94e-05	199	89	5	f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 ENAH HAS2 EEF1A1	4.94e-05	199	89	5	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PCSK1 ENPP2 CTSC KIAA1755 CHI3L1	4.94e-05	199	89	5	fcbb3a9c0f4c5b4c1f09db24b9f50cc1166fa43b
ToppCell	11.5-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	MFAP4 ENPP2 ENAH HAS2 EEF1A1	4.94e-05	199	89	5	cea1b30f3e3a9b4ccbc8b57f82352067be1a1d68
ToppCell	Control-NK\|Control / Disease condition and Cell class	SYNE1 CTSC PPM1L HLA-E HIPK2	4.94e-05	199	89	5	f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 SYNE1 CHI3L1 HAS2	4.94e-05	199	89	5	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 ENAH CHI3L1 EEF1A1	4.94e-05	199	89	5	e2d2224e7e9136bcc82d2e460dd7f7ab84b61a96
ToppCell	lymphoid-T_cell-CD8+_Naive_T_cell\|T_cell / Lineage, cell class and subclass	PARP1 SLC25A5 SLC25A6 HLA-E EEF1A1	4.94e-05	199	89	5	9ee40563e840a7fe97e7592539d42e19db438c64
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_DC2\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SLC25A5 SLC25A6 CASP1 MTDH EEF1A1	4.94e-05	199	89	5	829ec877c6c16c4abf8d3d139aea94af599406fe
ToppCell	COVID-19-kidney-Glomerular_EC\|kidney / Disease (COVID-19 only), tissue and cell type	HECW2 SYNE1 HLA-E SH3RF3 F8	4.94e-05	199	89	5	fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 SYNE1 CHI3L1 HAS2	5.06e-05	200	89	5	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	background-Hepatocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	ADH6 CYP2C8 CYP2C9 PCSK6 ADH1A	5.06e-05	200	89	5	787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 SYNE1 CHI3L1 HAS2	5.06e-05	200	89	5	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADH5 MFAP4 SYNE1 CHI3L1 HAS2	5.06e-05	200	89	5	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
Drug	beta-NADP	ADH5 ADH6 CYP2C8 CYP2C9 HK1 HK2 CTSC KCNAB2 XDH MTDH F8 ADH1A	4.57e-07	490	89	12	CID000000929
Drug	NADP(H	ADH5 ADH6 CYP2C8 CYP2C9 HK1 HK2 KCNAB2 XDH HAS2 HAS3 MTDH ADH1A	9.83e-07	527	89	12	CID000000930
Drug	Ptpc	HK1 HK2 SLC25A5 SLC25A6 CASP1	2.43e-06	55	89	5	CID003036276
Drug	disulfiram	ADH5 CYP2C9 CASP1 CHI3L1 HAS2 HAS3 ADH1A	2.90e-06	158	89	7	CID000003117
Drug	2-NA	ADH5 ADH6 ADH1A	4.77e-06	9	89	3	CID000074128
Drug	(3R,7R)-17-(6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol	ADH5 ADH6 ADH1A	4.77e-06	9	89	3	CID000440672
Drug	3-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate	PARP1 CYP2C8 CYP2C9	4.77e-06	9	89	3	ctd:C109602
Drug	cyclophosphamide	CYP2C8 CYP2C9 HK1 THPO HK2 IL36B CASP1 CELA1 F8	5.40e-06	327	89	9	CID000002907
Drug	willardine	ADH5 ADH6 GRIK3 ADH1A	7.21e-06	32	89	4	CID000005123
Drug	walrycin A	ADH6 CYP2C8 XDH ADH1A	7.21e-06	32	89	4	ctd:C574123
Drug	2,2,2-trichloroethanol	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	9.93e-06	73	89	5	CID000008259
Drug	hexa-2,4-dien-1-ol	ADH5 ADH6 ADH1A	1.24e-05	12	89	3	CID000008104
Drug	2-naphthaldehyde	ADH5 ADH6 ADH1A	1.61e-05	13	89	3	CID000006201
Drug	emend	CYP2C8 CYP2C9 B3GAT1 ADH1A	1.79e-05	40	89	4	CID000151165
Drug	naphthalenemethanol	ADH5 ADH6 ADH1A	2.04e-05	14	89	3	CID000020908
Drug	6-[(3R,7R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanal	ADH5 ADH6 ADH1A	2.54e-05	15	89	3	CID000440673
Drug	2,4-dinitrophenol	HK1 SLC25A5 SLC25A6 CTSC SORBS1	2.76e-05	90	89	5	CID000001493
Drug	naphthaldehyde	ADH5 ADH6 ADH1A	3.12e-05	16	89	3	CID000006195
Drug	CID5288005	HK1 HK2 SLC25A5 SLC25A6	3.72e-05	48	89	4	CID005288004
Drug	glucitol-6-phosphate	HK1 HK2 MTDH ADH1A	4.04e-05	49	89	4	CID000000618
Drug	glutathione reduced	ADH5 ADH6 PARP1 CYP2C9 HK1 CASP1 XDH HAS2 HAS3 ADH1A	4.48e-05	534	89	10	CID000000745
Drug	styrene glycol	ADH5 CYP2C8 CYP2C9	4.52e-05	18	89	3	CID000007149
Drug	Cyclohexenes	CYP2C8 CYP2C9	4.52e-05	3	89	2	ctd:D053138
Drug	ortho-Aminobenzoates	CYP2C8 CYP2C9	4.52e-05	3	89	2	ctd:D062367
Drug	Clodronate	SLC25A5 SLC25A6	4.52e-05	3	89	2	DB00720
Drug	CP094	TINAG HK1 HK2 HAS2 HAS3 SMAD7	4.68e-05	165	89	6	CID000086322
Drug	FT T	CYP2C8 CYP2C9 HK1 HK2	4.74e-05	51	89	4	CID000445622
Drug	N-tosyl-L-phenylalanine chloromethyl ketone	RAF1 PARP1 CASP1 CELA1 EEF1A1 SMAD7	4.84e-05	166	89	6	CID000009824
Drug	C x F	HAS2 HAS3 ADH1A	5.35e-05	19	89	3	CID000013017
Drug	AC1L1IIA	HK1 HK2 SLC25A5 SLC25A6 CASP1 MAP3K7	5.89e-05	172	89	6	CID000004591
Drug	agaric acid	HK1 SLC25A5 SLC25A6	6.27e-05	20	89	3	CID000012629
Drug	Ritonavir	PARP1 CYP2C8 CYP2C9 CIITA CASP1	6.91e-05	109	89	5	ctd:D019438
Drug	thiocoraline	CYP2C8 CYP2C9	9.02e-05	4	89	2	ctd:C109005
Drug	4-isopropylphenol	CYP2C8 CYP2C9	9.02e-05	4	89	2	ctd:C028690
Drug	lofenal	HK1 HK2	9.02e-05	4	89	2	CID000159256
Drug	dehydroabietylamine	SLC25A5 SLC25A6	9.02e-05	4	89	2	ctd:C000600819
Drug	Sulfadiazine	CYP2C8 CYP2C9	9.02e-05	4	89	2	ctd:D013411
Drug	N-bromoacetylglucosamine	HK1 HK2	9.02e-05	4	89	2	CID000152920
Drug	AC1L5VHN	HK1 HK2	9.02e-05	4	89	2	CID000235938
Drug	2,3-anhydro-D-allose	HK1 HK2	9.02e-05	4	89	2	CID000191595
Drug	1,5-anhydroglucitol 6-phosphate	HK1 HK2	9.02e-05	4	89	2	CID003081444
Drug	1-deoxy-D-manno-heptulose	HK1 HK2	9.02e-05	4	89	2	CID000193198
Drug	4-quinolinecarboxamide	CYP2C9 B3GAT1	9.02e-05	4	89	2	CID003753329
Drug	3'-amino-3'-deoxythymidine	PARP1 CYP2C8 CYP2C9	9.66e-05	23	89	3	CID000108074
Drug	uridine 5'-diphosphoglucuronic acid	ADH5 HAS2 HAS3 CRB1 EEF1A1 EEF1A2	9.92e-05	189	89	6	CID000000390
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	PARP1 RBM25 HK1 KCNAB2 USP48 SMAD7	1.18e-04	195	89	6	2942_UP
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	PNPLA6 RHBDF2 FAM3A ARFGAP1 TNRC6B SMAD7	1.24e-04	197	89	6	7171_DN
Drug	Aconitine	RAF1 CYP2C8 CYP2C9	1.25e-04	25	89	3	ctd:D000157
Drug	Tolbutamide	CYP2C8 CYP2C9 HK1	1.25e-04	25	89	3	ctd:D014044
Drug	1,4-naphthoquinone	CYP2C8 CYP2C9 XDH	1.41e-04	26	89	3	ctd:C035342
Drug	L-ester	PARP1 CASP1 XDH	1.41e-04	26	89	3	CID000467321
Drug	galangin	PARP1 CYP2C9 CASP1 SMAD7	1.47e-04	68	89	4	ctd:C037032
Drug	3-chloromethylthiochromone-1,1-dioxide	HK1 HK2	1.50e-04	5	89	2	CID000100620
Drug	NSC-167055	SYNE1 EEF1A2	1.50e-04	5	89	2	CID005383385
Drug	bufuralol	CYP2C8 CYP2C9	1.50e-04	5	89	2	ctd:C010831
Drug	2-fluoro-2-deoxy-6-phosphogluconate	HK1 HK2	1.50e-04	5	89	2	CID000127270
Drug	chloral hydrate	ADH5 ADH6 CYP2C8 CYP2C9 ADH1A	1.53e-04	129	89	5	CID000002707
Drug	TC-3	PCSK1 HK1 SYNE1 PCSK6	1.55e-04	69	89	4	CID000398798
Drug	licochalcone A	CYP2C8 CYP2C9 XDH	1.58e-04	27	89	3	ctd:C070840
Drug	Streptozocin	PCSK1 RAF1 PARP1 TINAG HK1 SLC25A5 ENPP2 CASP1 XDH ABCG8 SMAD7	1.74e-04	756	89	11	ctd:D013311
Drug	(hydrochloride)	CYP2C8 CYP2C9 CTSC	1.96e-04	29	89	3	CID000004923
Drug	dhmal	ADH5 ADH6 ADH1A	1.96e-04	29	89	3	CID000151725
Drug	7-hydroxy-4-trifluoromethylcoumarin	CYP2C8 CYP2C9 XDH	1.96e-04	29	89	3	CID005375667
Drug	AC1L1AOQ	ADH5 ADH6 ADH1A	2.17e-04	30	89	3	CID000001082
Drug	4,4'-cyclohexylidenebisphenol	CYP2C8 CYP2C9	2.24e-04	6	89	2	ctd:C570106
Drug	4',5-dihydroxydiclofenac	CYP2C8 CYP2C9	2.24e-04	6	89	2	CID003052567
Drug	AC1O5Z5L	CYP2C8 CYP2C9	2.24e-04	6	89	2	CID006443527
Drug	3'-hydroxydiclofenac	CYP2C8 CYP2C9	2.24e-04	6	89	2	CID000112230
Drug	4-methylumbelliferyl phenylphosphonate	PCSK1 ENPP2	2.24e-04	6	89	2	CID000134928
Drug	8-thiocyano-ATP	HK1 HK2	2.24e-04	6	89	2	CID000132196
Drug	8,9-epoxyeicosatrienoic acid	CYP2C8 CYP2C9	2.24e-04	6	89	2	ctd:C050715
Drug	glyceraldehyde	ADH5 ADH6 HK1 HK2 ADH1A	2.24e-04	140	89	5	CID000000751
Drug	2-amino-3-phosphonopropionic acid	ADH5 CASP1 GRIK3 ADH1A	2.26e-04	76	89	4	CID000003857
Drug	Cimetidine	ADH5 CYP2C9 CASP1 ADH1A	2.26e-04	76	89	4	ctd:D002927
Drug	Imatinib Mesylate	RAF1 PARP1 CYP2C8 HK2 EEF1A1	2.32e-04	141	89	5	ctd:D000068877
Drug	aniline	CYP2C8 CYP2C9 SYNE1 HAS2 HAS3	2.40e-04	142	89	5	CID000006115
Drug	benzyloxyresorufin	CYP2C8 CYP2C9 HAS2 HAS3	2.50e-04	78	89	4	CID000114982
Disease	developmental and epileptic encephalopathy 33 (implicated_via_orthology)	EEF1A1 EEF1A1P5 EEF1A2	2.56e-08	3	88	3	DOID:0080463 (implicated_via_orthology)
Disease	obesity (is_implicated_in)	PCSK1 HK1 HK2 SORBS1 ABCG8	7.99e-06	91	88	5	DOID:9970 (is_implicated_in)
Disease	nervous system disorder	CYP2C8 CYP2C9 PNPLA6 ARFGAP1	1.93e-05	53	88	4	C0027765
Disease	ecosanoids measurement	CYP2C8 CYP2C9 ABCG8 ADH1A	2.24e-05	55	88	4	EFO_0020044
Disease	autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)	SLC25A5 SLC25A6	5.26e-05	4	88	2	DOID:0111517 (implicated_via_orthology)
Disease	pulmonary hypertension (biomarker_via_orthology)	HK1 HAS2 HAS3 SMAD7	9.82e-05	80	88	4	DOID:6432 (biomarker_via_orthology)
Disease	epilepsy (implicated_via_orthology)	SLC25A5 SLC25A6 EEF1A1 EEF1A1P5 EEF1A2	1.31e-04	163	88	5	DOID:1826 (implicated_via_orthology)
Disease	cysteine measurement	TTL GRIK3	3.12e-04	9	88	2	EFO_0021000
Disease	Obesity	PCSK1 PARP1 HK2 PPM1L CASP1	3.78e-04	205	88	5	C0028754
Disease	cholestasis (biomarker_via_orthology)	ADH5 XDH ABCG8	4.28e-04	49	88	3	DOID:13580 (biomarker_via_orthology)
Disease	alcohol dependence measurement	ADH6 BPTF ADH1A	6.01e-04	55	88	3	EFO_0007835
Disease	Cardiomyopathies	RAF1 PARP1 CYP2C9 THPO	6.30e-04	130	88	4	C0878544
Disease	apolipoprotein B measurement	RAF1 BPTF HK1 NPEPPS PCSK6 EFCAB13 SV2C ABCG8	8.26e-04	663	88	8	EFO_0004615
Disease	ascending aortic diameter	PCSK1 ENPP2 TNRC6B HAS2	8.31e-04	140	88	4	EFO_0021787
Disease	chenodeoxycholate measurement	CYP2C8 SMAD7	9.00e-04	15	88	2	EFO_0010471
Disease	pancreatic adenocarcinoma (is_implicated_in)	RAF1 SMAD7	9.00e-04	15	88	2	DOID:4074 (is_implicated_in)
Disease	Hepatitis	PARP1 ENPP2	9.00e-04	15	88	2	C0019158
Disease	16a-hydroxy DHEA 3-sulfate measurement	CYP2C8 CYP2C9	9.00e-04	15	88	2	EFO_0800301
Disease	andro steroid monosulfate C19H28O6S (1) measurement	CYP2C8 CYP2C9	1.03e-03	16	88	2	EFO_0800305
Disease	hyperglycemia (implicated_via_orthology)	PCSK1 HK2	1.16e-03	17	88	2	DOID:4195 (implicated_via_orthology)
Disease	Cardiomyopathies, Primary	PARP1 CYP2C9 THPO	1.16e-03	69	88	3	C0033141
Disease	Myocardial Diseases, Secondary	PARP1 CYP2C9 THPO	1.16e-03	69	88	3	C0036529
Disease	brain connectivity measurement	NPEPPS ENPP2 CTSC HAS3 MAP3K7 SH3RF3	1.27e-03	400	88	6	EFO_0005210
Disease	brain measurement, neuroimaging measurement	BPTF ENPP2 EFCAB13 KIAA1755 HAS3 MAP3K7 SH3RF3	1.30e-03	550	88	7	EFO_0004346, EFO_0004464
Disease	serum hepcidin measurement	EML6 KIAA1755	1.30e-03	18	88	2	EFO_0004504
Disease	Malignant neoplasm of breast	RAF1 PARP1 OTOF SYNE1 EFCAB13 CELA1 XDH GRIK3 SORBS1 MTDH	1.35e-03	1074	88	10	C0006142
Disease	cardioembolic stroke	HK1 PCSK6 KIAA1755 RPL3L	1.70e-03	170	88	4	EFO_1001976
Disease	dilated cardiomyopathy (implicated_via_orthology)	EEF1A1 EEF1A1P5 EEF1A2	1.78e-03	80	88	3	DOID:12930 (implicated_via_orthology)
Disease	liver cirrhosis (is_marker_for)	PARP1 THPO SMAD7	1.91e-03	82	88	3	DOID:5082 (is_marker_for)
Disease	non-alcoholic fatty liver disease	RAF1 BPTF HK1 IL36B	2.18e-03	182	88	4	EFO_0003095
Disease	cholelithiasis	FAM3A TNRC6B ABCG8	2.34e-03	88	88	3	EFO_0004799
Disease	Kidney Diseases	PARP1 CYP2C8 CASP1	2.34e-03	88	88	3	C0022658
Disease	Ataxia	HK1 PITRM1	2.52e-03	25	88	2	C0004134
Disease	acute kidney failure (implicated_via_orthology)	CASP1 XDH	2.94e-03	27	88	2	DOID:3021 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RVNGAGKVVGWKTVF	B3GAT1	231	Q9P2W7
GGKAFFKGAWSNVLR	SLC25A6	266	P12236
AIVLGGTGWGFKNVK	ADAM23	806	O75077
GTGWGFKNVKKRRFD	ADAM23	811	O75077
TGRTWKGAILGGFKS	ADH1A	311	P07327
KGSVFGGWKSRQHIP	ADH6	316	P28332
FQLVTGRTWKGTAFG	ADH5	306	P11766
GTAFGGWKSVESVPK	ADH5	316	P11766
KAGQGKSYWAGAVSR	CIITA	421	P33076
QAAVKWGGAGAEKTR	C20orf204	46	A0A1B0GTL2
GGKAFFKGAWSNVLR	SLC25A5	266	P05141
TLGGFAKVSEKNQWG	ARID2	56	Q68CP9
ITKGLGIISSNGKRW	CYP2C8	106	P10632
RGHGGKIKSGQIWIN	ABCG8	121	Q9H221
ASKVQGVGSKGWRDV	ARFGAP1	276	Q8N6T3
GWFKTGDTVVFKDGQ	ACSF3	451	Q4G176
AGEFKWNGSVHGSKV	BPTF	886	Q12830
GAWKTISNGFGFKDA	RAF1	6	P04049
GLVLSWKRVQGASGK	RBM25	111	P49756
WKRVQGASGKLQAFG	RBM25	116	P49756
FRSWGRVGTVIGSNK	PARP1	586	P09874
WDSKNRGVTGTQKGQ	HECW2	106	Q9P2P5
KAVFGGWSRGNVIEK	PNPLA6	1251	Q8IY17
GAVVAAVIWRKKSSG	HLA-E	321	P13747
GRGTFGQVVKCWKRG	HIPK2	206	Q9H2X6
KGQGVSVEVTSKGRW	KIAA1755	1076	Q5JYT7
TVSWSKAGAQLGARG	HMCN2	3881	Q8NDA2
WTKGFKSSGVEGRDV	HK2	171	P52789
KTLLSVGGWNFGSQR	CHI3L1	91	P36222
VGGWNFGSQRFSKIA	CHI3L1	96	P36222
KKGRQGLGSIFVWAS	PCSK6	331	P29122
WDVFTHSGKGKVLGN	LCTL	66	Q6UWM7
VVGRGAFGVVCKAKW	MAP3K7	41	O43318
LDGKKWQTYRGNSTG	F8	2126	P00451
YITGWGKTKTNGQLA	CELA1	146	Q9UNI1
WTKRFKASGVEGADV	HK1	171	P19367
GTFGQVVKCWKRGTN	HIPK3	206	Q9H422
TTKIFWGGKAETERG	KCNAB2	116	Q13303
FKAGTGAWQAKSSSV	KIF19	711	Q2TAC6
DSWVFVGAKGVQNKS	FAM3A	181	P98173
SGHGGAVAGKKNRTW	INO80C	91	Q6PI98
TCVGNWFGKGKRGFI	SLC37A2	166	Q8TED4
WGIGVGRKKWKSSFQ	IL36B	126	Q9NZH7
GGWAGDSVKASKFRR	IFT43	61	Q96FT9
VWDDKSFKGVTVGRG	KDM1B	421	Q8NB78
GVVWFKDSVGVSGNL	CASP1	291	P29466
FKGWKVERKEGNASG	EEF1A2	211	Q05639
FKGWKVTRKDGNASG	EEF1A1	211	P68104
ATINKAGWGTSGRKT	HAS2	456	Q92819
AGWGTSGRKTIVVNF	HAS2	461	Q92819
GRNWACFTGKKVGTA	CTSC	131	P53634
KNTWQIRKFLGGVGS	EFCAB13	361	Q8IY85
VNGGGWNEKSVKLSS	MTDH	281	Q86UE4
FKGWKVTRKDGNASG	EEF1A1P5	211	Q5VTE0
GTWFKDGVKLTTQDG	IGFN1	486	Q86VF2
INKSGWGTSGRKTIV	HAS3	461	O00219
WGTSGRKTIVVNFIG	HAS3	466	O00219
KKWVPAGGSTGFSRV	ENAH	21	Q8N8S7
KFWQQAGGGFTSKRG	EML6	841	Q6ZMW3
ANRGFGIVFSNGKKW	CYP2C9	106	P11712
DGFLWVKSGSVTTKG	CRB1	491	P82279
WEGLTGRIVFNKTSG	GRIK3	371	Q13003
VDTAKKNFGGGNTAW	CRELD2	46	Q6UXH1
VAGGSKHGRKAAWKF	NPEPPS	816	P55786
WITATKQGVKAGTFF	ENPP2	261	Q13822
KQGVKAGTFFWSVVI	ENPP2	266	Q13822
KRGFGSAGWTVQAKV	OTOF	896	Q9HC10
FFWGGLADKVGRKQS	SV2C	206	Q496J9
WTAGQGQAVRKGATL	TAPBPL	241	Q9BX59
TGIEVKDFGKSWRSG	SYNE1	196	Q8NF91
AVTKGRGVKGVTSRW	RPL3L	221	Q92901
GGKWTVFQKRFNGSV	MFAP4	76	P55083
TLQSFGKAVDWAKSG	PITRM1	931	Q5JRX3
RIKRAGGFISFNGSW	PPM1L	241	Q5SGD2
WFKGTLQRNGKTGLF	SH3RF1	866	Q7Z6J0
QKTWQESGRVFKGLG	XIRP2	3306	A4UGR9
SNIWGTKFKIVGLAA	TULP4	601	Q9NRJ4
TGFTVQISFVKGWGQ	SMAD7	391	O15105
VGSWVKGLISRGASF	USPL1	756	Q5W0Q7
HGWTGTGKNFVSKII	TOR1A	101	O14656
GEWGFQKGQEISAKA	STBD1	151	O95210
WFKGASLRTGVSGVF	SH3RF3	501	Q8TEJ3
DGWFVGTSRRTKQFG	SORBS1	1266	Q9BX66
WFAGKQVKSVASVGG	XDH	336	P47989
VFGSKGLRVVKISWG	WDR6	86	Q9NNW5
IWKGQNGRTFKVGSF	TNK1	421	Q13470
TGWGTLRGAQGQKEK	TINAG	416	Q9UJW2
QSIRKGAAQWFGVSG	RHBDF2	116	Q6PJF5
GSKSDWRLGVIKGTA	TRIM50	356	Q86XT4
VKGSDGFWVGKSSLR	USP48	586	Q86UV5
VWIAKSSAGAKGEGI	TTL	146	Q8NG68
TNKAWAKGDIQGAGA	TMEM91	121	Q6ZNR0
GGKEAGTESRFKQWT	TNRC6B	1386	Q9UPQ9
ARTTGSGLLKWQQGF	THPO	211	P40225
GKWLELGSKSGARFS	MYBPC2	91	Q14324
GVKQGRQGKGSIFVW	PCSK1	291	P29120