Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear steroid receptor activity	PDE3A ESRRA ESRRG	6.87e-05	25	64	3	GO:0003707
GeneOntologyMolecularFunction	protein kinase activity	MST1R STRADB ATR RPS6KA5 BCKDK NRG2 ULK4 CDKL1 PTK7	1.19e-04	600	64	9	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	MST1R STRADB ATR RPS6KA5 BCKDK NRG2 ULK4 CDKL1 PTK7	4.09e-04	709	64	9	GO:0016773
GeneOntologyMolecularFunction	estrogen response element binding	ESRRA ESRRG	5.46e-04	11	64	2	GO:0034056
GeneOntologyMolecularFunction	kinase activity	MST1R STRADB ATR RPS6KA5 BCKDK NRG2 ULK4 CDKL1 PTK7	7.01e-04	764	64	9	GO:0016301
GeneOntologyMolecularFunction	nuclear receptor activity	PDE3A ESRRA ESRRG	9.43e-04	60	64	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	PDE3A ESRRA ESRRG	9.90e-04	61	64	3	GO:0098531
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	MST1R NRG2 PTK7	1.19e-03	65	64	3	GO:0004714
GeneOntologyMolecularFunction	protein tyrosine kinase activity	MST1R RPS6KA5 NRG2 PTK7	1.21e-03	145	64	4	GO:0004713
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	SPSB1 SPSB4 SPSB2	2.32e-03	82	64	3	GO:1990756
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	MST1R NRG2 PTK7	2.57e-03	85	64	3	GO:0019199
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	MST1R STRADB ATR RPS6KA5 BCKDK NRG2 ULK4 CDKL1 PTK7	2.89e-03	938	64	9	GO:0016772
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	SPSB1 SPSB4 SPSB2	3.52e-03	95	64	3	GO:0140767
GeneOntologyMolecularFunction	histone kinase activity	ATR RPS6KA5	3.62e-03	28	64	2	GO:0035173
GeneOntologyBiologicalProcess	cerebrospinal fluid circulation	CFAP54 CFAP221 ULK4	3.13e-05	20	64	3	GO:0090660
GeneOntologyBiologicalProcess	regulation of double-strand break repair	EPC2 ATR SMARCD1 SMARCD2 TFIP11	9.04e-05	146	64	5	GO:2000779
GeneOntologyBiologicalProcess	axon ensheathment in central nervous system	ULK4 MYRF B4GALT6	1.45e-04	33	64	3	GO:0032291
GeneOntologyBiologicalProcess	central nervous system myelination	ULK4 MYRF B4GALT6	1.45e-04	33	64	3	GO:0022010
MousePheno	abnormal brain ependyma motile cilium physiology	CFAP54 EFHC1 ULK4	2.05e-05	17	45	3	MP:0011069
MousePheno	abnormal ependyma motile cilium physiology	CFAP54 EFHC1 ULK4	2.46e-05	18	45	3	MP:0011068
MousePheno	absent brain ependyma motile cilia	CFAP54 ULK4	6.05e-05	4	45	2	MP:0011057
Domain	Oest-rel_rcp	ESRRA ESRRG	3.57e-05	3	65	2	IPR027289
Domain	SWIB_domain	SMARCD1 SMARCD2	3.57e-05	3	65	2	IPR019835
Domain	SWIB	SMARCD1 SMARCD2	3.57e-05	3	65	2	SM00151
Domain	VWA_2	INTS6L INTS6	1.18e-04	5	65	2	PF13519
Domain	SWIB	SMARCD1 SMARCD2	1.18e-04	5	65	2	PF02201
Domain	Oest_rcpt/oest-rel_rcp	ESRRA ESRRG	1.18e-04	5	65	2	IPR024178
Domain	SWIB_MDM2_domain	SMARCD1 SMARCD2	1.77e-04	6	65	2	IPR003121
Domain	-	SMARCD1 SMARCD2	1.77e-04	6	65	2	1.10.245.10
Domain	SOCS_box	SPSB1 SPSB4 SPSB2	3.11e-04	38	65	3	PF07525
Domain	INT_SG_DDX_CT_C	INTS6L INTS6	3.29e-04	8	65	2	PF15300
Domain	INT_SG_DDX_CT_C	INTS6L INTS6	3.29e-04	8	65	2	IPR029307
Domain	SOCS_box	SPSB1 SPSB4 SPSB2	3.36e-04	39	65	3	SM00969
Domain	SOCS	SPSB1 SPSB4 SPSB2	3.36e-04	39	65	3	PS50225
Domain	SOCS_box	SPSB1 SPSB4 SPSB2	3.36e-04	39	65	3	IPR001496
Domain	Retinoid-X_rcpt/HNF4	ESRRA ESRRG	5.27e-04	10	65	2	IPR000003
Domain	TPR-like_helical_dom	SART3 CFAP54 ATR USP28 TTC21A	1.30e-03	233	65	5	IPR011990
Domain	Kinase-like_dom	MST1R STRADB ATR RPS6KA5 ULK4 CDKL1 PTK7	2.71e-03	542	65	7	IPR011009
Domain	SPRY	SPSB1 SPSB4 SPSB2	3.46e-03	87	65	3	SM00449
Domain	SPRY	SPSB1 SPSB4 SPSB2	4.30e-03	94	65	3	PF00622
Domain	SPRY_dom	SPSB1 SPSB4 SPSB2	4.30e-03	94	65	3	IPR003877
Domain	B30.2/SPRY	SPSB1 SPSB4 SPSB2	4.43e-03	95	65	3	IPR001870
Domain	B302_SPRY	SPSB1 SPSB4 SPSB2	4.43e-03	95	65	3	PS50188
Domain	Prot_kinase_dom	MST1R STRADB RPS6KA5 ULK4 CDKL1 PTK7	7.00e-03	489	65	6	IPR000719
Domain	ConA-like_dom	SPSB1 SPSB4 NEURL4 SPSB2	7.13e-03	219	65	4	IPR013320
Domain	PROTEIN_KINASE_DOM	MST1R STRADB RPS6KA5 ULK4 CDKL1 PTK7	7.28e-03	493	65	6	PS50011
Pubmed	The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.	SPSB1 SPSB4 SPSB2	6.81e-08	5	67	3	16369487
Pubmed	The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.	SPSB1 SPSB4 SPSB2	1.36e-07	6	67	3	20603330
Pubmed	Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.	SPSB1 SPSB4 SPSB2	1.36e-07	6	67	3	20561531
Pubmed	The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway.	SPSB1 SPSB4 SPSB2	1.36e-07	6	67	3	15713673
Pubmed	Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.	SPSB1 SPSB4 SPSB2	2.38e-07	7	67	3	21199876
Pubmed	Expression of estrogen receptor-related receptor isoforms and clinical significance in endometrial adenocarcinoma.	ESRRA ESRRG	3.66e-06	2	67	2	16681769
Pubmed	Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis.	ESRRA ESRRG	3.66e-06	2	67	2	17229846
Pubmed	Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function.	ESRRA ESRRG	3.66e-06	2	67	2	25624346
Pubmed	Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.	ESRRA ESRRG	3.66e-06	2	67	2	17488637
Pubmed	Repression of osteoblast maturation by ERRα accounts for bone loss induced by estrogen deficiency.	ESRRA ESRRG	3.66e-06	2	67	2	23359549
Pubmed	Estrogen receptor (ER) and ER-related receptor expression in normal and atrophic human vagina.	ESRRA ESRRG	3.66e-06	2	67	2	18328649
Pubmed	Isolation and functional characterization of a novel endogenous inverse agonist of estrogen related receptors (ERRs) from human pregnancy urine.	ESRRA ESRRG	3.66e-06	2	67	2	30954508
Pubmed	Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression.	ESRRA ESRRG	3.66e-06	2	67	2	17157980
Pubmed	Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells.	ESRRA ESRRG	3.66e-06	2	67	2	19822186
Pubmed	VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.	SPSB1 SPSB4 SPSB2	5.46e-06	18	67	3	15601820
Pubmed	Kaempferol is an estrogen-related receptor alpha and gamma inverse agonist.	ESRRA ESRRG	1.10e-05	3	67	2	19171140
Pubmed	PGC-1alpha induces dynamic protein interactions on the ERRalpha gene multi-hormone response element nucleosome in kidney cells.	ESRRA ESRRG	1.10e-05	3	67	2	18673300
Pubmed	Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues.	ESRRA ESRRG	1.10e-05	3	67	2	15598686
Pubmed	Estrogen-related receptor-gamma and peroxisome proliferator-activated receptor-gamma coactivator-1alpha regulate estrogen-related receptor-alpha gene expression via a conserved multi-hormone response element.	ESRRA ESRRG	1.10e-05	3	67	2	15821111
Pubmed	TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.	SPSB1 SPSB2	1.10e-05	3	67	2	21876038
Pubmed	A PPARα promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetes.	ESRRA ESRRG	1.10e-05	3	67	2	20838448
Pubmed	ERRα and ERRγ coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation.	ESRRA ESRRG	1.10e-05	3	67	2	39231208
Pubmed	Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation.	ESRRA ESRRG	1.10e-05	3	67	2	29888756
Pubmed	Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice.	SMARCD1 SMARCD2	1.10e-05	3	67	2	27125315
Pubmed	Genetic interaction between central pair apparatus genes CFAP221, CFAP54, and SPEF2 in mouse models of primary ciliary dyskinesia.	CFAP54 CFAP221	1.10e-05	3	67	2	32704025
Pubmed	The E3 Ligases Spsb1 and Spsb4 Regulate RevErbα Degradation and Circadian Period.	SPSB1 SPSB4	1.10e-05	3	67	2	31607207
Pubmed	Array MAPPIT: high-throughput interactome analysis in mammalian cells.	SPSB1 SPSB4 SPSB2	1.72e-05	26	67	3	19159283
Pubmed	ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency.	ESRRA ESRRG	2.19e-05	4	67	2	25865501
Pubmed	Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha.	ESRRA ESRRG	2.19e-05	4	67	2	12181319
Pubmed	Target specificities of estrogen receptor-related receptors: analysis of binding sequences and identification of Rb1-inducible coiled-coil 1 (Rb1cc1) as a target gene.	ESRRA ESRRG	2.19e-05	4	67	2	18039682
Pubmed	Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma.	ESRRA ESRRG	2.19e-05	4	67	2	29940916
Pubmed	Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.	ATR SMARCD1 SMARCD2	2.67e-05	30	67	3	31043422
Pubmed	Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.	SMARCD1 SMARCD2	3.64e-05	5	67	2	9693044
Pubmed	Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.	ESRRA ESRRG	3.64e-05	5	67	2	19690166
Pubmed	Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif.	ESRRA ESRRG	3.64e-05	5	67	2	18063693
Pubmed	The ECS(SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthase.	SPSB1 SPSB2	3.64e-05	5	67	2	21549100
Pubmed	Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.	SPSB1 SPSB2	3.64e-05	5	67	2	28270450
Pubmed	Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors.	ESRRA ESRRG	3.64e-05	5	67	2	18509053
Pubmed	Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells.	SPSB1 SPSB4	3.64e-05	5	67	2	16672355
Pubmed	SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors.	SPSB1 SPSB2	5.46e-05	6	67	2	31085591
Pubmed	Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases.	ESRRA ESRRG	5.46e-05	6	67	2	21177257
Pubmed	Receptor-interacting protein 140 differentially regulates estrogen receptor-related receptor transactivation depending on target genes.	ESRRA ESRRG	5.46e-05	6	67	2	16439465
Pubmed	Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.	ESRRA ESRRG	5.46e-05	6	67	2	23836911
Pubmed	Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.	TMEM98 MYRF	5.46e-05	6	67	2	31048900
Pubmed	The SOCS box: a tale of destruction and degradation.	SPSB1 SPSB4 SPSB2	6.91e-05	41	67	3	12076535
Pubmed	Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.	SMARCD1 SMARCD2	7.63e-05	7	67	2	28369036
Pubmed	RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.	ATR SPSB1	7.63e-05	7	67	2	25916848
Pubmed	Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.	HORMAD2 ATR	7.63e-05	7	67	2	22549958
Pubmed	Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein.	TMEM98 MYRF	7.63e-05	7	67	2	30249802
Pubmed	SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.	HORMAD2 ATR	1.02e-04	8	67	2	30393076
Pubmed	HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.	HORMAD2 ATR	1.02e-04	8	67	2	23039116
Pubmed	Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.	SPSB1 SPSB4	1.02e-04	8	67	2	28931592
Pubmed	Perm1 promotes cardiomyocyte mitochondrial biogenesis and protects against hypoxia/reoxygenation-induced damage in mice.	ESRRA ESRRG	1.30e-04	9	67	2	34029594
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	SMARCD1 SMARCD2	1.63e-04	10	67	2	12665591
Pubmed	Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.	SMARCD1 SMARCD2	1.63e-04	10	67	2	34716243
Pubmed	The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.	TMEM98 MYRF	1.63e-04	10	67	2	32236127
Pubmed	The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.	ASF1B SMARCD1 SMARCD2	1.67e-04	55	67	3	35945219
Pubmed	A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.	MST1R PTK7	1.99e-04	11	67	2	8247543
Pubmed	Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm.	SMARCD1 SMARCD2	2.38e-04	12	67	2	33723076
Pubmed	Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.	PDE3A IFNLR1	2.81e-04	13	67	2	21844884
Pubmed	Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.	SMARCD1 SMARCD2	2.81e-04	13	67	2	11726552
Pubmed	Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.	SMARCD1 SMARCD2	3.28e-04	14	67	2	8895581
Pubmed	Structural and functional insights into the B30.2/SPRY domain.	SPSB1 SPSB2	3.28e-04	14	67	2	16498413
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	SART3 ABR LAMB2 TFIP11 NEURL4	3.50e-04	313	67	5	38270169
Pubmed	Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.	SMARCD1 SMARCD2	3.78e-04	15	67	2	11175787
Pubmed	PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.	SMARCD1 SMARCD2	3.78e-04	15	67	2	15985610
Pubmed	Regulation of dendritic development by neuron-specific chromatin remodeling complexes.	SMARCD1 SMARCD2	3.78e-04	15	67	2	17920018
Pubmed	The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.	SMARCD1 SMARCD2	3.78e-04	15	67	2	11263494
Pubmed	Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.	SMARCD1 SMARCD2	4.31e-04	16	67	2	35390516
Pubmed	The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.	SMARCD1 SMARCD2	4.88e-04	17	67	2	11078522
Pubmed	PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.	ESRRA ESRRG	4.88e-04	17	67	2	36230906
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	INTS6L SART3 CIB2 ASF1B LAMB2 SMARCD1 SPSB4 IFNLR1 PTK7	5.21e-04	1215	67	9	15146197
Pubmed	BAF complexes facilitate decatenation of DNA by topoisomerase IIα.	SMARCD1 SMARCD2	5.48e-04	18	67	2	23698369
Pubmed	mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.	SMARCD1 SMARCD2	5.48e-04	18	67	2	14559996
Pubmed	Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.	SMARCD1 SMARCD2	6.12e-04	19	67	2	12110891
Pubmed	BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.	SMARCD1 SMARCD2	6.12e-04	19	67	2	18809673
Pubmed	Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.	SMARCD1 SMARCD2	6.12e-04	19	67	2	16932743
Pubmed	Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.	SMARCD1 SMARCD2	6.12e-04	19	67	2	25066234
Pubmed	Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.	SMARCD1 SMARCD2	6.79e-04	20	67	2	9128241
Pubmed	Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.	PDE3A ESRRG	8.24e-04	22	67	2	24376456
Pubmed	Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.	ESRRA ESRRG	9.01e-04	23	67	2	24349082
Pubmed	Diversity and specialization of mammalian SWI/SNF complexes.	SMARCD1 SMARCD2	9.01e-04	23	67	2	8804307
Pubmed	FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.	SMARCD1 SMARCD2	9.01e-04	23	67	2	30962207
Pubmed	Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.	ESRRA ESRRG	9.82e-04	24	67	2	37543677
Pubmed	The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.	SMARCD1 SMARCD2	9.82e-04	24	67	2	12215535
Pubmed	SWI/SNF chromatin remodeling and cancer.	SMARCD1 SMARCD2	9.82e-04	24	67	2	11790558
Pubmed	Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.	SMARCD1 SMARCD2	9.82e-04	24	67	2	10078207
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	ZNF438 EFHC1 DQX1 GPR153 SPSB1 ESRRG SPAG9	1.09e-03	832	67	7	36724073
Pubmed	Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.	SMARCD1 SMARCD2	1.15e-03	26	67	2	10778858
Pubmed	Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.	SMARCD1 SMARCD2	1.24e-03	27	67	2	29374058
Pubmed	REST repression of neuronal genes requires components of the hSWI.SNF complex.	SMARCD1 SMARCD2	1.34e-03	28	67	2	12192000
Pubmed	Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.	SMARCD1 SMARCD2	1.44e-03	29	67	2	15525990
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	GABBR1 PTK7	1.64e-03	31	67	2	11431694
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ATR USP28 SMARCD1 SMARCD2 API5	1.83e-03	453	67	5	29656893
Cytoband	3p14.3	KCTD6 DNAH12	8.89e-04	30	67	2	3p14.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3p14	KCTD6 DNAH12 C3orf49	1.15e-03	140	67	3	chr3p14
Cytoband	17q21.33	SPAG9 ACSF2	1.66e-03	41	67	2	17q21.33
Cytoband	3q23	ATR SPSB4	1.91e-03	44	67	2	3q23
Cytoband	Ensembl 112 genes in cytogenetic band chr3q23	ATR SPSB4	3.87e-03	63	67	2	chr3q23
Cytoband	Xq26.3	ZNF449 INTS6L	4.36e-03	67	67	2	Xq26.3
GeneFamily	Integrator complex	INTS6L INTS6	3.98e-04	15	36	2	1366
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	MST1R PTK7	2.87e-03	40	36	2	321
GeneFamily	Nuclear hormone receptors	ESRRA ESRRG	4.27e-03	49	36	2	71
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHI1-DT CFAP54 EFHC1 DNAH12 TTC21A CFAP221 ULK4	6.70e-09	169	67	7	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP54 EFHC1 DNAH12 CFAP221 ESRRG ULK4	1.45e-08	189	67	7	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP54 EFHC1 DNAH12 CFAP221 ESRRG ULK4	1.68e-08	193	67	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	HORMAD2 COL8A2 CFAP54 DNAH12 CFAP221 IFNLR1	2.27e-07	171	67	6	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 CFAP54 EFHC1 TTC21A CFAP221 ULK4	3.28e-07	182	67	6	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 CFAP54 EFHC1 TTC21A CFAP221 ULK4	3.28e-07	182	67	6	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	AHI1-DT CFAP54 EFHC1 DNAH12 CFAP221 ESRRG	4.49e-07	192	67	6	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP54 EFHC1 DNAH12 ESRRG ULK4	4.63e-07	193	67	6	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP54 EFHC1 DNAH12 TTC21A CFAP221 CDKL1	4.92e-07	195	67	6	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 DNAH12 TTC21A CFAP221 ULK4 CDKL1	5.22e-07	197	67	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	5.32e-06	167	67	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	5.64e-06	169	67	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	MST1R TMEM98 LAMB2 ALS2CL MYRF	6.14e-06	172	67	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_C\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF449 SPSB1 FASTKD3 KDSR	7.20e-06	82	67	4	32ab4ee9c39b976b1ddf68864a256a0e942327ff
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT PDE3A CFAP54 CFAP221 ESRRG	9.21e-06	187	67	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	9.21e-06	187	67	5	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	9.70e-06	189	67	5	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.05e-05	192	67	5	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.05e-05	192	67	5	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A ULK4	1.10e-05	194	67	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.13e-05	195	67	5	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.13e-05	195	67	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.13e-05	195	67	5	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.13e-05	195	67	5	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.13e-05	195	67	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.16e-05	196	67	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.16e-05	196	67	5	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.16e-05	196	67	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	AHI1-DT CFAP54 DNAH12 CFAP221 ESRRG	1.16e-05	196	67	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.19e-05	197	67	5	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.19e-05	197	67	5	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.19e-05	197	67	5	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.27e-05	200	67	5	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.27e-05	200	67	5	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.27e-05	200	67	5	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CFAP54 EFHC1 DNAH12 TTC21A CFAP221	1.27e-05	200	67	5	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4\|TCGA-Cervix / Sample_Type by Project: Shred V9	CFAP54 EFHC1 TTC21A CFAP221	6.25e-05	142	67	4	369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT CFAP54 CFAP221 ULK4	6.42e-05	143	67	4	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	Control-PLT_4\|World / Disease Group and Platelet Clusters	KCTD6 DNAH12 ATR SPSB1	8.56e-05	154	67	4	a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MELTF PDE3A LAMB2 KDSR	1.02e-04	161	67	4	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AHI1-DT ALS2CL MYRF IFNLR1	1.14e-04	166	67	4	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	IL13RA2 CFAP54 DNAH12 TTC21A	1.14e-04	166	67	4	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHI1-DT CFAP54 EFHC1 DNAH12	1.22e-04	169	67	4	8bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASF1B TTC21A NRG2 B4GALT6	1.28e-04	171	67	4	fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASF1B TTC21A NRG2 B4GALT6	1.28e-04	171	67	4	f15594fd4d709920733de9376a391dedc62b65de
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP54 TTC21A CFAP221 ULK4	1.37e-04	174	67	4	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP54 TTC21A CFAP221 ULK4	1.40e-04	175	67	4	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	REPS1 ASF1B SPSB1 TTC21A	1.40e-04	175	67	4	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF449 TMEM98 MYRF IFNLR1	1.43e-04	176	67	4	33323c97afe509147956b8df9f92ca6b0537e604
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	1.43e-04	176	67	4	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1R CFAP54 CFAP221 ULK4	1.46e-04	177	67	4	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TMEM98 LAMB2 MYRF CCDC116	1.53e-04	179	67	4	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 DNAH12 TTC21A CFAP221	1.53e-04	179	67	4	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 TTC21A	1.56e-04	180	67	4	92fb01b91261b3103454924cde56add337b41844
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 EFHC1 ESRRA ESRRG	1.56e-04	180	67	4	9ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 EFHC1 ESRRA ESRRG	1.56e-04	180	67	4	729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT PDE3A ESRRG PTK7	1.59e-04	181	67	4	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	AHI1-DT CFAP54 DNAH12 ESRRG	1.63e-04	182	67	4	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASF1B SPSB4 FASTKD3 CCDC116	1.63e-04	182	67	4	11494a66d986297b837332ee9d382b71b9f22591
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	CFAP54 DNAH12 ASF1B ULK4	1.66e-04	183	67	4	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	1.70e-04	184	67	4	2df903924df9cb71039159416bcbe6a6614e21fe
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	AHI1-DT CFAP54 DNAH12 ESRRG	1.73e-04	185	67	4	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 DNAH12 TTC21A CFAP221	1.73e-04	185	67	4	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF438 PDE3A DNAH12 CDKL1	1.73e-04	185	67	4	709236097cbfc254796fcc69b5f5178b73dad9bd
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF438 PDE3A DNAH12 CDKL1	1.73e-04	185	67	4	af078a6c4a3e0b54b7d8ab7b30dcd06053ebfd28
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 PDE3A EFHC1 ESRRA	1.77e-04	186	67	4	d4e327cc1d7b618654ffe0ff6475fe8e8cc5cb01
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT CFAP54 CFAP221 ESRRG	1.77e-04	186	67	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMB2 ALS2CL MYRF C3orf49	1.81e-04	187	67	4	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INTS6L MELTF ESRRG CDKL1	1.84e-04	188	67	4	9d384c0934f1461bc37b1f83e0877d7bee2116ee
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	EFHC1 DNAH12 TTC21A CFAP221	1.84e-04	188	67	4	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INTS6L MELTF ESRRG CDKL1	1.84e-04	188	67	4	340f0e3e65c7a00d82d26621ff37107458bebc41
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFAP54 EFHC1 DNAH12 TTC21A	1.84e-04	188	67	4	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFHC1 DNAH12 CFAP221 ESRRG	1.88e-04	189	67	4	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	AHI1-DT CFAP54 DNAH12 ESRRG	1.88e-04	189	67	4	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	1.92e-04	190	67	4	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFAP54 EFHC1 DNAH12 TTC21A	1.92e-04	190	67	4	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFAP54 EFHC1 DNAH12 TTC21A	1.92e-04	190	67	4	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	1.92e-04	190	67	4	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP54 EFHC1 DNAH12 TTC21A	1.96e-04	191	67	4	acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP54 DNAH12 ESRRG	1.96e-04	191	67	4	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP54 DNAH12 ESRRG	1.96e-04	191	67	4	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP54 DNAH12 ESRRG	1.96e-04	191	67	4	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	2.00e-04	192	67	4	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	EFHC1 DNAH12 TTC21A CFAP221	2.00e-04	192	67	4	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	2.04e-04	193	67	4	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	Bronchial_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	2.04e-04	193	67	4	3e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.04e-04	193	67	4	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 EFHC1 TTC21A CFAP221	2.04e-04	193	67	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP54 DNAH12 CFAP221 ESRRG	2.08e-04	194	67	4	958e648138676d46698090b4046cb484083ae449
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	2.08e-04	194	67	4	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 EFHC1 DNAH12 CFAP221	2.08e-04	194	67	4	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.08e-04	194	67	4	a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	CFAP54 EFHC1 DNAH12 CFAP221	2.08e-04	194	67	4	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP54 DNAH12 CFAP221 ESRRG	2.12e-04	195	67	4	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.12e-04	195	67	4	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP54 DNAH12 CFAP221 ESRRG	2.12e-04	195	67	4	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.12e-04	195	67	4	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	CFAP54 EFHC1 TTC21A CFAP221	2.12e-04	195	67	4	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.12e-04	195	67	4	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP54 EFHC1 DNAH12 CFAP221	2.12e-04	195	67	4	581b04220587e1d5198b1abd6965965ace7803e7
Disease	nanophthalmos (is_implicated_in)	TMEM98 MYRF	1.39e-05	3	64	2	DOID:0080634 (is_implicated_in)
Disease	Coffin-Siris syndrome (implicated_via_orthology)	SMARCD1 SMARCD2	1.65e-04	9	64	2	DOID:1925 (implicated_via_orthology)
Disease	Microphthalmos	TMEM98 MYRF	2.52e-04	11	64	2	C0026010
Disease	systemic lupus erythematosus	KCTD6 AHI1-DT MELTF NEURL4 CCDC116 IFNLR1 GABBR1 KDM4B	3.24e-04	799	64	8	MONDO_0007915
Disease	metabolite measurement, diet measurement	MST1R MYRF GABBR1	5.01e-04	71	64	3	EFO_0004725, EFO_0008111
Disease	2-hydroxyglutarate measurement	ESRRG STPG4	5.45e-04	16	64	2	EFO_0021506
Disease	vital capacity	ZNF438 HORMAD2 AHI1-DT MELTF PDE3A SPSB1 SMARCD2 C3orf49 KDM4B	1.34e-03	1236	64	9	EFO_0004312
Disease	azoospermia (implicated_via_orthology)	ESRRA ESRRG	1.57e-03	27	64	2	DOID:14227 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YINQLEALLLPMKPL	ABR	106	Q12979
YKLPMDDLLPLLIYV	ALS2CL	876	Q60I27
PLPIYRGKDMPDLND	EPC2	16	Q52LR7
DRPPKETEPMVLLLY	CFAP54	2941	Q96N23
PASRQLSPLEPKLYM	CCDC116	551	Q8IYX3
KTPEQLRMILPNPLY	ACSF2	296	Q96CM8
FDKLLEYMPLPPEEA	API5	311	Q9BZZ5
LQPPAPLIMPYLDDA	AHI1-DT	226	P0C7V0
PMPLDYILPELLKNA	BCKDK	266	O14874
LLLRKPNTYPKMIPE	IL13RA2	361	Q14627
MPYNYPVLLPLLDDL	INTS6L	386	Q5JSJ4
VMPYNYPVLLPLLDD	INTS6	381	Q9UL03
ELMLPEKLRPLYNHP	MPC2	21	O95563
MKNLPVPVYLRPLDE	SPAG9	666	O60271
QLPPCMPPLDLKYEV	IFNLR1	146	Q8IU57
ELLYNDPIKIILMPG	GABBR1	231	Q9UBS5
IRKLYILMQDLEPLP	HORMAD2	161	Q8N7B1
FLDKPILAPEPLVMD	PDE3A	666	Q14432
CLEKLPLRLYMPDPK	NRG2	381	O14511
PLRLYMPDPKQKAEE	NRG2	386	O14511
PQLYPLRPLQEDKMQ	GPR153	371	Q6NV75
AEQYPKLLFDLMPII	DNAH12	3011	Q6ZR08
EELEAKPRPIIPMLY	KDM4B	516	O94953
PKAMDYDLLLRLEPQ	LAMB2	616	P55268
ILKSEPPYPQEMSAL	RPS6KA5	271	O75582
PPYPQEMSALAKDLI	RPS6KA5	276	O75582
MLVELAPPYFLSNLP	DQX1	666	Q8TE96
FMYLKPLSILPLEQG	OR8B12	256	Q8NGG6
EYLNPELRENPPMKP	ASF1B	116	Q9NVP2
PELMADYLQPKLLGI	ATR	1116	Q13535
PMLNLPNKDLGLEYL	CDHR2	1221	Q9BYE9
MAQPQLYLPEPFKIA	C3orf49	1	Q96BT1
LPCPEKLPYMRGFLN	B4GALT6	106	Q9UBX8
DMEPLELKFPNISYP	CDKL1	246	Q00532
LLVAEPEKIYAMPDP	ESRRG	241	P62508
GQYLEMPLPLLPMDL	COL8A2	61	P25067
LNPPEKMALDPYTEL	EFHC1	201	Q5JVL4
LIQCLNDPKPLYPMD	KCTD6	101	Q8NC69
LPYSMQEPDTKLRPL	SART3	711	Q15020
LLVVEPEKLYAMPDP	ESRRA	201	P11474
LYMVSPLISPKPLAL	KDSR	16	Q06136
FQELLLLPEDYFMPP	NEURL4	1346	Q96JN8
DPGLVFNQLPKMLYP	OSGIN1	321	Q9UJX0
KPPEALAMSLDYDPL	CFAP221	641	Q4G0U5
GYDLPEKLPESLMPK	REPS1	356	Q96D71
AMKGLLCDPNRLPPY	MELTF	351	P08582
LMLDYQPPQFKLDPR	SMARCD1	286	Q96GM5
LMEPFGKLNYLPPNA	FASTKD3	411	Q14CZ7
PADPMELKNLEYRPV	SURF1	106	Q15526
PYALQPELYLLPVMD	SPATA1	126	Q5VX52
LLMLDHQPPQYKLDP	SMARCD2	301	Q92925
ELAPNLVPMDYRKSP	CIB2	36	O75838
VDPQLLKMALTPYPK	SPG11	1111	Q96JI7
YINGLDPEPLPLMDL	SPSB4	226	Q96A44
YCKPTRLDLLLDMPP	SPSB1	31	Q96BD6
YLNGLDPEPLPLMDL	SPSB1	226	Q96BD6
LPQYMPPDFLDLLKK	STPG4	96	Q8N801
QVSALPLPPAMKRYL	SPSB2	246	Q99619
PARFPLPDMLKYVIE	USP28	436	Q96RU2
KAAPALIDPLYLMAQ	TTC21A	496	Q8NDW8
MLLQKLKGPPYSPLD	STRADB	276	Q9C0K7
LPQPEGCPSKLYRLM	PTK7	1026	Q13308
MSLPENLKLPIPRYQ	ZNF438	111	Q7Z4V0
MELLPPLPQSFLLLL	MST1R	1	Q04912
LPLMQARLEPLYSPI	TFIP11	556	Q9UBB9
QNFLDPGYPLPKLDM	ZNF449	181	Q6P9G9
PDPVPAYALKLLVAM	ULK4	1001	Q96C45
MYPPLDPKLLDARTT	TMEM98	146	Q9Y2Y6
QKGEYLPLRPLPMFE	GARIN5B	31	Q8N5Q1
LQRDLYMKAEPPIPH	MYRF	201	Q9Y2G1