Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase binding	TPR KIF13B NSF BLNK RB1CC1 CBL WNK1 ITGB1 PTPN1 WWC2 TIAM1 CLTC CD44 PPP1R9B IGSF9B PRKCZ CTNND1 UTRN MOB4 RNF138	4.53e-06	969	130	20	GO:0019900
GeneOntologyMolecularFunction	alpha-actinin binding	MAGI1 ITGB1 PTPRT XIRP2	4.71e-05	31	130	4	GO:0051393
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	TPR ANK3 KDM5A BCORL1 BLNK ZC3H18 ACTL6A JADE1 MED13L RB1CC1 KMT2E WNK1 USP16 MIER1 WWC2 MTA1 SHANK2 FLRT1 MOB4 GAB1	6.05e-05	1160	130	20	GO:0030674
GeneOntologyMolecularFunction	actinin binding	MAGI1 ITGB1 PTPRT XIRP2	1.74e-04	43	130	4	GO:0042805
GeneOntologyMolecularFunction	molecular adaptor activity	TPR ANK3 KDM5A BCORL1 BLNK PSMD4 ZC3H18 ACTL6A JADE1 MED13L RB1CC1 KMT2E WNK1 USP16 MIER1 WWC2 MTA1 SHANK2 FLRT1 MOB4 GAB1	1.77e-04	1356	130	21	GO:0060090
GeneOntologyMolecularFunction	protein kinase binding	TPR KIF13B NSF BLNK RB1CC1 CBL WNK1 ITGB1 PTPN1 TIAM1 CLTC CD44 PRKCZ CTNND1 UTRN RNF138	1.78e-04	873	130	16	GO:0019901
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAGI1 TPR KIF13B ANK3 MAP1B PACSIN1 MYO10 ADGRV1 REEP3 ITGB1 PTPRT TIAM1 XIRP2 ARHGEF10 CLTC PPP1R9B UTRN KIF2C	2.75e-04	1099	130	18	GO:0008092
GeneOntologyMolecularFunction	cadherin binding	ANK3 CBL ITGB1 PTPRT PPL PTPN1 NEO1 CTNND1 CDH7	3.84e-04	339	130	9	GO:0045296
GeneOntologyMolecularFunction	protein tyrosine kinase binding	BLNK CBL ITGB1 PTPN1 TIAM1 CTNND1	4.35e-04	149	130	6	GO:1990782
GeneOntologyMolecularFunction	histone modifying activity	KDM5A JADE1 KMT2E USP16 MIER1 SETDB2 KAT14	7.62e-04	229	130	7	GO:0140993
GeneOntologyMolecularFunction	ephrin receptor binding	CBL PTPN1 TIAM1	1.16e-03	32	130	3	GO:0046875
GeneOntologyBiologicalProcess	positive regulation of cell adhesion	MAGI1 ANK3 SPP1 MYO10 VTCN1 ACTL6A BCL6 ZBTB7B ITGB1 SLC7A1 RIN2 CD44 ZFHX3 PRKCZ UTRN	4.20e-06	579	131	15	GO:0045785
GeneOntologyBiologicalProcess	cell-cell adhesion	MAGI1 ANK3 PDGFRA MYO10 VTCN1 ACTL6A ADGRV1 BCL6 ZBTB7B WNK1 ITGB1 PTPRT BMP5 SLC7A1 NEO1 CD44 CD58 IGSF9B PRKCZ CTNND1 CDH7	4.23e-06	1077	131	21	GO:0098609
GeneOntologyBiologicalProcess	mitotic cell cycle	TPR TICRR AKAP8 ANK3 ACTL6A JADE1 BCL6 KMT2E WNK1 REEP3 ITGB1 USP16 SETDB2 ARHGEF10 NFIX CLTC PPP1R9B KAT14 MYBL1 KIF2C	6.22e-06	1014	131	20	GO:0000278
GeneOntologyBiologicalProcess	mitotic cell cycle process	TPR TICRR AKAP8 ANK3 ACTL6A JADE1 BCL6 KMT2E WNK1 REEP3 ITGB1 USP16 ARHGEF10 NFIX CLTC PPP1R9B KAT14 KIF2C	7.77e-06	854	131	18	GO:1903047
GeneOntologyBiologicalProcess	chromatin organization	TPR EPC2 ATRX KDM5A ACTR5 BCORL1 NAP1L3 ZDBF2 ACTL6A JADE1 BCL6 KMT2E USP16 MIER1 SETDB2 MTA1 KAT14 MYBL1	1.49e-05	896	131	18	GO:0006325
GeneOntologyBiologicalProcess	protein-DNA complex organization	TPR EPC2 ATRX KDM5A ACTR5 BCORL1 NAP1L3 ZDBF2 ACTL6A JADE1 BCL6 KMT2E USP16 MIER1 SETDB2 MTA1 TAF7L KAT14 MYBL1	1.81e-05	999	131	19	GO:0071824
GeneOntologyBiologicalProcess	chromatin remodeling	TPR ATRX KDM5A ACTR5 NAP1L3 ZDBF2 ACTL6A JADE1 BCL6 KMT2E USP16 MIER1 SETDB2 MTA1 KAT14 MYBL1	1.94e-05	741	131	16	GO:0006338
GeneOntologyBiologicalProcess	regulation of cell adhesion	MAGI1 ANK3 SPP1 MYO10 CYTH1 VTCN1 ACTL6A BCL6 ZBTB7B WNK1 ITGB1 SLC7A1 RIN2 CD44 ZFHX3 PRKCZ UTRN	8.14e-05	927	131	17	GO:0030155
GeneOntologyCellularComponent	asymmetric synapse	ANK3 MAP1B NSF PACSIN1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 PPP1R9B IGSF9B PRKCZ CTNND1	8.94e-06	477	130	13	GO:0032279
GeneOntologyCellularComponent	anchoring junction	MAGI1 ANK3 CYTH1 GIT2 CBL ITGB1 PPL SH3PXD2B TIAM1 XIRP2 SCN2A CLTC CD44 PPP1R9B PRKCZ FLRT1 CTNND1 CDH7 GAB1	9.70e-06	976	130	19	GO:0070161
GeneOntologyCellularComponent	neuron to neuron synapse	ANK3 MAP1B NSF PACSIN1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 PPP1R9B IGSF9B PRKCZ CTNND1	2.36e-05	523	130	13	GO:0098984
GeneOntologyCellularComponent	postsynaptic density	ANK3 MAP1B NSF PACSIN1 PTPRT NEO1 SHANK2 TIAM1 PPP1R9B IGSF9B PRKCZ CTNND1	2.54e-05	451	130	12	GO:0014069
GeneOntologyCellularComponent	synaptic membrane	ANK3 PACSIN1 CYTH1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 SCN2A CLTC PPP1R9B IGSF9B UTRN	7.17e-05	583	130	13	GO:0097060
GeneOntologyCellularComponent	postsynaptic specialization	ANK3 MAP1B NSF PACSIN1 PTPRT NEO1 SHANK2 TIAM1 PPP1R9B IGSF9B PRKCZ CTNND1	7.29e-05	503	130	12	GO:0099572
GeneOntologyCellularComponent	cell-cell junction	MAGI1 ANK3 CYTH1 ITGB1 PPL TIAM1 SCN2A PPP1R9B PRKCZ FLRT1 CTNND1 CDH7 GAB1	8.23e-05	591	130	13	GO:0005911
GeneOntologyCellularComponent	paranode region of axon	KIF13B ANK3 SCN2A	1.50e-04	17	130	3	GO:0033270
GeneOntologyCellularComponent	postsynapse	ANK3 MAP1B NSF PACSIN1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 CLTC PPP1R9B IGSF9B PRKCZ CTNND1 UTRN MOB4 KIF2C	1.94e-04	1018	130	17	GO:0098794
GeneOntologyCellularComponent	main axon	KIF13B ANK3 MAP1B TIAM1 SCN2A	2.35e-04	89	130	5	GO:0044304
GeneOntologyCellularComponent	actin-based cell projection	KIF13B PDGFRA MYO10 ADGRV1 ITGB1 CD44 PPP1R9B UTRN	3.55e-04	278	130	8	GO:0098858
GeneOntologyCellularComponent	myelin sheath	NSF PACSIN1 ITGB1 CLTC PRKCZ UQCRFS1P1 ATP5F1C	4.23e-04	217	130	7	GO:0043209
GeneOntologyCellularComponent	dendritic spine	MAP1B ITGB1 SHANK2 TIAM1 PPP1R9B CTNND1 MOB4	8.08e-04	242	130	7	GO:0043197
GeneOntologyCellularComponent	growth cone	MAP1B CBL NEO1 SHANK2 TIAM1 PPP1R9B CTNND1	8.68e-04	245	130	7	GO:0030426
GeneOntologyCellularComponent	neuron spine	MAP1B ITGB1 SHANK2 TIAM1 PPP1R9B CTNND1 MOB4	9.10e-04	247	130	7	GO:0044309
GeneOntologyCellularComponent	postsynaptic membrane	ANK3 PACSIN1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 IGSF9B UTRN	9.86e-04	405	130	9	GO:0045211
GeneOntologyCellularComponent	site of polarized growth	MAP1B CBL NEO1 SHANK2 TIAM1 PPP1R9B CTNND1	1.05e-03	253	130	7	GO:0030427
GeneOntologyCellularComponent	cell leading edge	PACSIN1 MYO10 ADGRV1 ITGB1 TIAM1 CD44 PPP1R9B PRKCZ CTNND1 FGD6	1.15e-03	500	130	10	GO:0031252
GeneOntologyCellularComponent	axon	KIF13B ANK3 MAP1B PDGFRA PACSIN1 GIT2 CBL NEO1 SHANK2 TIAM1 SCN2A PPP1R9B PRKCZ CTNND1	1.32e-03	891	130	14	GO:0030424
GeneOntologyCellularComponent	myelin sheath abaxonal region	ITGB1 PRKCZ	1.34e-03	9	130	2	GO:0035748
GeneOntologyCellularComponent	bicellular tight junction	MAGI1 ANK3 CYTH1 PRKCZ CTNND1	1.37e-03	131	130	5	GO:0005923
GeneOntologyCellularComponent	cell projection membrane	PACSIN1 MYO10 ADGRV1 ITGB1 SHANK2 TIAM1 CD44 PPP1R9B UTRN	1.52e-03	431	130	9	GO:0031253
GeneOntologyCellularComponent	distal axon	MAP1B PACSIN1 GIT2 CBL NEO1 SHANK2 TIAM1 PPP1R9B CTNND1	1.62e-03	435	130	9	GO:0150034
GeneOntologyCellularComponent	extrinsic component of plasma membrane	CYTH1 PPL TIAM1 CTNND1 CDH7	1.67e-03	137	130	5	GO:0019897
GeneOntologyCellularComponent	flotillin complex	CBL CTNND1	1.67e-03	10	130	2	GO:0016600
GeneOntologyCellularComponent	glutamatergic synapse	MAP1B PACSIN1 ITGB1 PTPRT NEO1 SHANK2 TIAM1 SCN2A CLTC PRKCZ CTNND1 MOB4 KIF2C	1.76e-03	817	130	13	GO:0098978
GeneOntologyCellularComponent	tight junction	MAGI1 ANK3 CYTH1 PRKCZ CTNND1	1.78e-03	139	130	5	GO:0070160
GeneOntologyCellularComponent	ruffle	PACSIN1 MYO10 ITGB1 TIAM1 PPP1R9B FGD6	1.85e-03	206	130	6	GO:0001726
GeneOntologyCellularComponent	leading edge membrane	PACSIN1 ADGRV1 ITGB1 TIAM1 CD44 PPP1R9B	2.03e-03	210	130	6	GO:0031256
GeneOntologyCellularComponent	adherens junction	MAGI1 CYTH1 ITGB1 PPP1R9B CTNND1 CDH7	2.13e-03	212	130	6	GO:0005912
GeneOntologyCellularComponent	cell-cell contact zone	ANK3 ITGB1 TIAM1 SCN2A	2.83e-03	94	130	4	GO:0044291
GeneOntologyCellularComponent	histone acetyltransferase complex	EPC2 ACTL6A JADE1 KAT14	2.83e-03	94	130	4	GO:0000123
GeneOntologyCellularComponent	apical junction complex	MAGI1 ANK3 CYTH1 PRKCZ CTNND1	3.11e-03	158	130	5	GO:0043296
GeneOntologyCellularComponent	extrinsic component of membrane	CYTH1 PPL TIAM1 CLTC CTNND1 CDH7	3.19e-03	230	130	6	GO:0019898
GeneOntologyCellularComponent	lamellipodium	MYO10 ITGB1 CD44 PPP1R9B CTNND1 FGD6	3.19e-03	230	130	6	GO:0030027
GeneOntologyCellularComponent	somatodendritic compartment	ANK3 MAP1B NSF MYO10 ITGB1 NEO1 SHANK2 TIAM1 PPP1R9B CACNA1G IGSF9B PRKCZ FLRT1 CTNND1 SDC2 MOB4	4.00e-03	1228	130	16	GO:0036477
GeneOntologyCellularComponent	protein acetyltransferase complex	EPC2 ACTL6A JADE1 KAT14	4.07e-03	104	130	4	GO:0031248
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 KIF13B AKAP8 MAP1B PDGFRA KDM5A CBL WNK1 REEP3 VIRMA WWC2 SH3PXD2B TIAM1 ARHGEF10 SIK2 CTNND1 FGD6 UTRN GAB1 KIF2C	1.03e-10	861	132	20	36931259
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TPR KIF13B TICRR AEN ANK3 ATRX PEG3 JADE1 WNK1 ITGB1 MIER1 PACS1 SLC7A1 WWC2 SH3PXD2B MTA1 INTS2 CLTC ANKRD12 PRKCZ UTRN KIF2C	1.43e-10	1084	132	22	11544199
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	TPR EPC2 AEN ATRX PDGFRA KDM5A MYO10 PSMD4 ZDBF2 ZC3H18 JADE1 MED13L GCSH WNK1 ITGB1 USP16 VIRMA SLC7A1 INTS2 CLVS2 CLTC CPSF1 KAT14	1.10e-09	1327	132	23	32694731
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAGI1 TPR KIF13B AKAP8 ANK3 KDM5A NSF CYTH1 GIT2 VIRMA GDA ZNF263 SH3PXD2B SHANK2 CLTC PPP1R9B CTNND1 MOB4 KIF2C	4.61e-09	963	132	19	28671696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRMT9B MAGI1 ANK3 ATRX MAP1B BLNK ADGRV1 REEP3 ITGB1 PACS1 SLC7A1 SHANK2 INTS2 NFIX RIN2 PPP1R9B ZFHX3 IGSF9B ANKRD12 PRKCZ PNPLA7 CTNND1 UTRN	9.65e-09	1489	132	23	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR CDO1 AKAP8 ATRX KDM5A ZC3H18 USP16 VIRMA MIER1 PPL PACS1 WWC2 MTA1 CLTC CPSF1 WDR44	4.45e-08	774	132	16	15302935
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EPC2 TICRR AKAP8 ATRX KDM5A ACTR5 BCORL1 ZC3H18 ACTL6A ZFC3H1 ZBTB7B MIER1 ZBTB14 MTA1 INTS2 NFIX CPSF1 KAT14 KIF2C ATP5F1C	9.90e-08	1294	132	20	30804502
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ERICH1 AKAP8 ANK3 TEX9 ITGB1 PPL PTPN1 NEO1 CLTC CD44 ZFHX3 RPGR CTNND1 GAB1 ATP5F1C	2.89e-07	777	132	15	35844135
Pubmed	A human MAP kinase interactome.	MAGI1 TPR ANK3 PACSIN1 PSMD4 CBL WNK1 CLTC PRKCZ MOB4 GAB1 WDR44	3.72e-07	486	132	12	20936779
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B ATRX ZGRF1 BCORL1 ZDBF2 ZC3H18 GIT2 WNK1 GTF2F1 CLTC KAT14 GAB1 KIF2C	4.16e-07	588	132	13	38580884
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	MAGI1 TPR ACTL6A GIT2 VIRMA MTA1 TIAM1 ARHGEF10 CSTF1 CPSF1 PPP1R9B ARHGAP28 CTNND1 FGD6 UTRN ATP5F1C	4.30e-07	916	132	16	32203420
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KDM5A SETD6 PEG3 GIT2 BCL6 KMT2E WNK1 ITGB1 NEO1 XIRP2 CLTC UTRN	4.71e-07	497	132	12	23414517
Pubmed	Human transcription factor protein interaction networks.	EPC2 AKAP8 ATRX KDM5A ACTR5 BCORL1 PSMD4 ZC3H18 ACTL6A MIER1 ZBTB14 MTA1 PRCC NFIX GMEB1 CSTF1 CPSF1 ZFHX3 KAT14 ATP5F1C	4.77e-07	1429	132	20	35140242
Pubmed	Bioinformatics and cellular signaling.	UTP6 CYTH1 BLNK GIT2 ZBTB7B ITGB1 PRKCZ GAB1	5.11e-07	182	132	8	15102471
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ANK3 PSMD4 RB1CC1 ITGB1 PTPRT PACS1 PTPN1 WWC2 GTF2F1 TIAM1 CLTC CD44 CPSF1 PPP1R9B CTNND1 UTRN GAB1	5.16e-07	1049	132	17	27880917
Pubmed	RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.	UTP6 NVL ZC3H18 ACTL6A ZFC3H1 VIRMA CSTF1 PPP1R9B	5.32e-07	183	132	8	28186131
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	EPC2 MAP1B BCORL1 GIT2 MED13L XRCC4 WNK1 MIER1 GTF2F1 PPP1R9B UTRN KIF2C ATP5F1C	1.17e-06	645	132	13	25281560
Pubmed	The functional interactome landscape of the human histone deacetylase family.	UTP6 TPR AKAP8 KDM5A ACTL6A MIER1 MTA1 CPSF1 ANKRD12	1.73e-06	289	132	9	23752268
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MAGI1 ANK3 RB1CC1 CBL ITGB1 PPL PTPN1 SH3PXD2B SHANK2 CTNND1 UTRN GAB1	1.79e-06	565	132	12	25468996
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PACSIN1 GIT2 ADGRV1 MED13L WNK1 ARHGEF10 SIK2 CACNA1G	2.51e-06	225	132	8	12168954
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	TPR RNF113A ACTL6A GTF2F1 MTA1 PRCC CLTC CSTF1 CPSF1 UTRN KAT14	3.95e-06	506	132	11	30890647
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	AKAP8 ATRX KDM5A ACTR5 NSF CYTH1 ZFC3H1 ZBTB7B VIRMA GTF2F1 MTA1 SHANK2 INTS2 CSTF1 CD58 ZFHX3 UTRN KIF2C ATP5F1C	3.97e-06	1497	132	19	31527615
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ERICH1 AKAP8 NVL ZDBF2 TEX9 WNK1 REEP3 ITGB1 PTPN1 GTF2F1 NEO1 ARHGEF10 CTNND1	4.71e-06	733	132	13	34672954
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	ITGB1 CLTC CD44 PPP1R9B CTNND1 UTRN	6.20e-06	118	132	6	27377895
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	TPR MAP1B MYO10 PPL CTNND1 UTRN	6.20e-06	118	132	6	30979931
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	TPR MAP1B PSMD4 CLTC PRKCZ FGD6 UTRN	6.99e-06	184	132	7	23402259
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	UTP6 TPR NSF NVL PSMD4 ZC3H18 CLTC CD44 CSTF1 CPSF1 PPP1R9B CTNND1	8.69e-06	660	132	12	32780723
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	AKAP8 KDM5A NSF ZDBF2 ACTL6A MED13L INTS2 CLTC	1.01e-05	272	132	8	31010829
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MAGI1 KIF13B ANK3 ATRX NSF GIT2 XRCC4 WNK1 REEP3 PACS1 TIAM1 PRCC RPGR FGD6 MOB4 RNF138 KIF2C	1.12e-05	1321	132	17	27173435
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	MAP1B GIT2 CBL PACS1 CLTC CTNND1	1.18e-05	132	132	6	16944949
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	MAGI1 KIF13B ITGB1 MIER1 PACS1 SLC7A1 NEO1 CD44 CTNND1 FGD6 GAB1	1.19e-05	569	132	11	30639242
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	TPR AKAP8 MAP1B PSMD4 ITGB1 PTPN1 INTS2 PPP1R9B UTRN MOB4 ATP5F1C	1.27e-05	573	132	11	28330616
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	AKAP8 ANK3 ATRX NSF NVL ZFC3H1 RB1CC1 ITGB1 USP16 PTPN1 NEO1 TIAM1 ARHGEF10 PRCC CLTC SIK2 CTNND1 GAB1	1.38e-05	1487	132	18	33957083
Pubmed	In silico prediction of physical protein interactions and characterization of interactome orphans.	PDGFRA BCL6 PTPN1 PRKCZ CTNND1 GAB1	1.40e-05	136	132	6	25402006
Pubmed	Genetic association of osteopontin (OPN) and its receptor CD44 genes with susceptibility to Chinese gastric cancer patients.	SPP1 CD44	1.43e-05	2	132	2	25009318
Pubmed	Preferential up-regulation of osteopontin in primary central nervous system lymphoma does not correlate with putative receptor CD44v6 or CD44H expression.	SPP1 CD44	1.43e-05	2	132	2	23089492
Pubmed	Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.	SPP1 CD44	1.43e-05	2	132	2	15516973
Pubmed	Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms.	KDM5A CD44	1.43e-05	2	132	2	21935404
Pubmed	Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration.	SPP1 CD44	1.43e-05	2	132	2	10825241
Pubmed	Osteopontin expression is an independent adverse prognostic factor in resectable gastrointestinal stromal tumor and its interaction with CD44 promotes tumor proliferation.	SPP1 CD44	1.43e-05	2	132	2	20549562
Pubmed	Crystal retention capacity of cells in the human nephron: involvement of CD44 and its ligands hyaluronic acid and osteopontin in the transition of a crystal binding- into a nonadherent epithelium.	SPP1 CD44	1.43e-05	2	132	2	12506143
Pubmed	Common Variants in Osteopontin and CD44 Genes as Predictors of Treatment Outcome in Radiotherapy and Chemoradiotherapy for Non-Small Cell Lung Cancer.	SPP1 CD44	1.43e-05	2	132	2	38067149
Pubmed	ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function.	PACSIN1 SHANK2	1.43e-05	2	132	2	24751538
Pubmed	Immunosuppressive role of SPP1-CD44 in the tumor microenvironment of intrahepatic cholangiocarcinoma assessed by single-cell RNA sequencing.	SPP1 CD44	1.43e-05	2	132	2	36469154
Pubmed	Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.	TIAM1 CD44	1.43e-05	2	132	2	22427969
Pubmed	Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells.	SPP1 CD44	1.43e-05	2	132	2	17332338
Pubmed	Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44.	SPP1 CD44	1.43e-05	2	132	2	34070790
Pubmed	The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.	PDGFRA CBL	1.43e-05	2	132	2	9653117
Pubmed	Osteopontin mediation of disturbed flow-induced endothelial mesenchymal transition through CD44 is a novel mechanism of neointimal hyperplasia in arteriovenous fistulae for hemodialysis access.	SPP1 CD44	1.43e-05	2	132	2	36646166
Pubmed	Targeting Chondroitin Sulfate Reduces Invasiveness of Glioma Cells by Suppressing CD44 and Integrin β1 Expression.	ITGB1 CD44	1.43e-05	2	132	2	34944101
Pubmed	Role of osteopontin and CD44s expression for patients with hepatocellular carcinoma undergoing liver transplantation or resection.	SPP1 CD44	1.43e-05	2	132	2	19010227
Pubmed	The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis.	SPP1 TIAM1	1.43e-05	2	132	2	26821678
Pubmed	Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway.	SPP1 CD44	1.43e-05	2	132	2	18155656
Pubmed	Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NFκB signaling.	SPP1 CD44	1.43e-05	2	132	2	33647584
Pubmed	Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.	BLNK CBL	1.43e-05	2	132	2	17202354
Pubmed	The effect of hyaluronic acid on osteopontin and CD44 mRNA of fibroblast-like synoviocytes in patients with osteoarthritis of the knee.	SPP1 CD44	1.43e-05	2	132	2	22218639
Pubmed	Expression of CD44v6 and integrin-β1 for the prognosis evaluation of pancreatic cancer patients after cryosurgery.	ITGB1 CD44	1.43e-05	2	132	2	24004467
Pubmed	AKAP95 interacts with nucleoporin TPR in mitosis and is important for the spindle assembly checkpoint.	TPR AKAP8	1.43e-05	2	132	2	28379780
Pubmed	Osteopontin combined with CD44, a novel prognostic biomarker for patients with hepatocellular carcinoma undergoing curative resection.	SPP1 CD44	1.43e-05	2	132	2	18997126
Pubmed	Osteopontin stimulates apoptosis in adult cardiac myocytes via the involvement of CD44 receptors, mitochondrial death pathway, and endoplasmic reticulum stress.	SPP1 CD44	1.43e-05	2	132	2	24531809
Pubmed	Reciprocal interactions between tumor-associated macrophages and CD44-positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer.	SPP1 CD44	1.43e-05	2	132	2	23251004
Pubmed	Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts.	SPP1 CD44	1.43e-05	2	132	2	12162503
Pubmed	Single-cell transcriptome sequencing reveals SPP1-CD44-mediated macrophage-tumor cell interactions drive chemoresistance in TNBC.	SPP1 CD44	1.43e-05	2	132	2	38982317
Pubmed	The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy.	CBL ITGB1	1.43e-05	2	132	2	27693578
Pubmed	[Expressions of osteopontin and B7-H4 in epithelial ovarian neoplasm and their significance].	SPP1 VTCN1	1.43e-05	2	132	2	20038306
Pubmed	Clinical implication and mitotic effect of CD44 cleavage in relation to osteopontin/CD44 interaction and dysregulated cell cycle protein in gastrointestinal stromal tumor.	SPP1 CD44	1.43e-05	2	132	2	20146103
Pubmed	The osteopontin - CD44 pathway is superfluous for the development of autoimmune myocarditis.	SPP1 CD44	1.43e-05	2	132	2	16402410
Pubmed	Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts.	SPP1 CD44	1.43e-05	2	132	2	12730217
Pubmed	Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity.	SPP1 CD44	1.43e-05	2	132	2	18952835
Pubmed	Polarization and directed migration of murine neutrophils is dependent on cell surface expression of CD44.	SPP1 CD44	1.43e-05	2	132	2	15919379
Pubmed	Role of osteopontin in calcification in autoimmune pancreatitis.	SPP1 CD44	1.43e-05	2	132	2	18651220
Pubmed	Gottron's papules exhibit dermal accumulation of CD44 variant 7 (CD44v7) and its binding partner osteopontin: a unique molecular signature.	SPP1 CD44	1.43e-05	2	132	2	22456539
Pubmed	Immunohistochemical study of osteopontin and L-selectin in a rat endometriosis model and in human endometriosis.	SPP1 CD44	1.43e-05	2	132	2	17482182
Pubmed	Pancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis.	SPP1 CD44	1.43e-05	2	132	2	34418441
Pubmed	Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner.	SPP1 CD44	1.43e-05	2	132	2	22807608
Pubmed	The role of osteopontin and its receptor in meningioma development and progression.	SPP1 CD44	1.43e-05	2	132	2	29504367
Pubmed	Involvement of osteopontin and its signaling molecule CD44 in clinicopathological features of adult T cell leukemia.	SPP1 CD44	1.43e-05	2	132	2	21645921
Pubmed	Cancer stem-like cells enriched with CD29 and CD44 markers exhibit molecular characteristics with epithelial-mesenchymal transition in squamous cell carcinoma.	ITGB1 CD44	1.43e-05	2	132	2	22740085
Pubmed	Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3).	PEG3 ZIM2	1.43e-05	2	132	2	10708526
Pubmed	OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome.	SPP1 CD44	1.43e-05	2	132	2	17987038
Pubmed	PTP1B dephosphorylates N-ethylmaleimide-sensitive factor and elicits SNARE complex disassembly during human sperm exocytosis.	NSF PTPN1	1.43e-05	2	132	2	19208619
Pubmed	Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells.	SPP1 CD44	1.43e-05	2	132	2	17343740
Pubmed	BLNK negatively regulates innate antifungal immunity through inhibiting c-Cbl-mediated macrophage migration.	BLNK CBL	1.43e-05	2	132	2	39413134
Pubmed	Effect of ligand-receptor interaction of osteopontin-CD44 on the expression of hyaluronic acid in human knee osteoarthritic chondrocytes in vitro.	SPP1 CD44	1.43e-05	2	132	2	33051414
Pubmed	Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth.	SPP1 CD44	1.43e-05	2	132	2	24607407
Pubmed	A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption.	ANK3 ARHGEF10	1.43e-05	2	132	2	31372216
Pubmed	CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration.	TIAM1 CD44	1.43e-05	2	132	2	10636882
Pubmed	Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells.	SPP1 CD44	1.43e-05	2	132	2	12949055
Pubmed	In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression.	SPP1 CD44	1.43e-05	2	132	2	18678363
Pubmed	Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomes.	ANK3 SCN2A	1.43e-05	2	132	2	12036953
Pubmed	Osteopontin-CD44v6 interaction mediates calcium deposition via phospho-Akt in valve interstitial cells from patients with noncalcified aortic valve sclerosis.	SPP1 CD44	1.43e-05	2	132	2	25060796
Pubmed	Immuno-localization of CD44 and osteopontin in developing human kidney.	SPP1 CD44	1.43e-05	2	132	2	18787423
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ANK3 ITGB1 PACS1 TIAM1 CD44 CTNND1 UTRN GAB1 WDR44	1.48e-05	377	132	9	38117590
Pubmed	EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination.	CBL ITGB1 CLTC	1.49e-05	13	132	3	23874206
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAGI1 TPR ANK3 MAP1B NSF ZC3H18 ITGB1 PTPN1 CTNND1 GAB1 KIF2C ATP5F1C	1.74e-05	708	132	12	39231216
Pubmed	Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.	ITGB1 XIRP2 CTNND1	1.89e-05	14	132	3	17766470
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	EPC2 AKAP8 ZC3H18 ACTL6A	1.98e-05	42	132	4	35705031
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	UTP6 TPR AKAP8 ZC3H18 ACTL6A ZFC3H1 USP16 VIRMA PPL PTPN1 CLTC CPSF1 PPP1R9B CTNND1 KIF2C ATP5F1C	2.37e-05	1257	132	16	36526897
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UTP6 TPR EPC2 AKAP8 MAP1B KDM5A NSF ACTL6A ITGB1 MTA1 NFIX CTNND1 KIF2C	2.45e-05	857	132	13	25609649
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	MAP1B MYO10 ZDBF2 PTPRT NFIX	2.48e-05	90	132	5	15033168
Interaction	PHLDB2 interactions	MAGI1 KIF13B ANK3 PDGFRA RB1CC1 ZBTB7B VIRMA TIAM1 PIPSL	3.76e-07	143	130	9	int:PHLDB2
Interaction	YWHAH interactions	MAGI1 KIF13B TICRR AKAP8 KDM5A GIT2 RB1CC1 CBL WNK1 REEP3 VIRMA PACS1 WWC2 SH3PXD2B TIAM1 SIK2 PPP1R9B PRKCZ CTNND1 FGD6 UTRN GAB1 KIF2C	5.53e-07	1102	130	23	int:YWHAH
Interaction	TIAM1 interactions	MAGI1 KIF13B ANK3 WNK1 VIRMA TIAM1 ARHGEF10 CD44 PPP1R9B PRKCZ	8.79e-07	205	130	10	int:TIAM1
Interaction	ZBTB21 interactions	MAGI1 KIF13B ATRX REEP3 VIRMA ZBTB14 TIAM1 CPSF1 FGD6	1.02e-06	161	130	9	int:ZBTB21
Interaction	YWHAG interactions	MAGI1 KIF13B TICRR AKAP8 CYTH1 GIT2 RB1CC1 CBL WNK1 REEP3 VIRMA PACS1 WWC2 TIAM1 CLTC SIK2 PPP1R9B PRKCZ CTNND1 FGD6 UTRN GAB1 KIF2C	4.57e-06	1248	130	23	int:YWHAG
Interaction	DYNLL1 interactions	TPR MAP1B MYO10 ZC3H18 RB1CC1 XRCC4 WWC2 MTA1 SHANK2 CD44 SIK2 PPP1R9B PRKCZ MOB4	5.52e-06	510	130	14	int:DYNLL1
Interaction	CSNK1A1 interactions	KIF13B RNF113A ZDBF2 ZC3H18 RB1CC1 XRCC4 ITGB1 TIAM1 CLTC SIK2 CPSF1 ATP5F1C	6.82e-06	381	130	12	int:CSNK1A1
Interaction	YWHAB interactions	MAGI1 KIF13B TICRR AKAP8 RB1CC1 CBL WNK1 REEP3 ITGB1 VIRMA WWC2 TIAM1 KCNG1 CLTC SIK2 PPP1R9B PRKCZ CTNND1 FGD6 GAB1	7.76e-06	1014	130	20	int:YWHAB
Interaction	RHOA interactions	MAGI1 AKAP8 ANK3 NSF NVL ITGB1 VIRMA PTPN1 SLC7A1 TIAM1 ARHGEF10 CLTC CD44 PPP1R9B PRKCZ RPGR CTNND1 UTRN SDC2 MOB4 GAB1 ATP5F1C	8.14e-06	1199	130	22	int:RHOA
Interaction	SFN interactions	MAGI1 KIF13B MAP1B ZC3H18 JADE1 CBL WNK1 REEP3 VIRMA WWC2 TIAM1 ARHGEF10 CLTC SIK2 FGD6 GAB1	1.00e-05	692	130	16	int:SFN
Interaction	RCOR1 interactions	TPR ZGRF1 RNF113A BCORL1 ZDBF2 GIT2 RB1CC1 VIRMA MIER1 MTA1 ZFHX3 UTRN KAT14	1.90e-05	494	130	13	int:RCOR1
Interaction	HDAC1 interactions	TPR ATRX KDM5A ZGRF1 RNF113A ZDBF2 ACTL6A BCL6 RB1CC1 KMT2E ZBTB7B VIRMA MIER1 MTA1 NFIX ZFHX3 UTRN KAT14 MOB4 RNF138	2.80e-05	1108	130	20	int:HDAC1
Interaction	BCR interactions	ANK3 ATRX MAP1B LRRK1 CBL VIRMA PTPN1 PPP1R9B UTRN	2.98e-05	244	130	9	int:BCR
Interaction	USP7 interactions	TPR ATRX SPP1 MYO10 ZGRF1 RNF113A PEG3 BCORL1 NAP1L3 PSMD4 ZDBF2 BCL6 XRCC4 KMT2E VIRMA PPL SAMD9L SCN2A CLTC RPGR UTRN UQCRFS1P1	3.31e-05	1313	130	22	int:USP7
Interaction	CDC42 interactions	MAGI1 ANK3 NSF ZC3H18 GIT2 RB1CC1 CBL WNK1 ITGB1 PTPN1 SLC7A1 TIAM1 INTS2 ARHGEF10 CLTC CD44 SIK2 PPP1R9B PRKCZ CTNND1 UTRN ATP5F1C	3.71e-05	1323	130	22	int:CDC42
Interaction	KIF13B interactions	MAGI1 KIF13B BCL6 REEP3 VIRMA TIAM1 FGD6	3.82e-05	142	130	7	int:KIF13B
Interaction	ASAP1 interactions	PACSIN1 RNF113A LRRK1 CBL VIRMA GAB1	4.16e-05	98	130	6	int:ASAP1
Interaction	ACTC1 interactions	TPR RNF113A ACTL6A VIRMA GTF2F1 MTA1 PRCC NFIX CLTC CSTF1 CPSF1 PPP1R9B UTRN KAT14 RNF138	4.21e-05	694	130	15	int:ACTC1
Interaction	AKT1 interactions	ATRX PDGFRA NSF JADE1 WNK1 PPL PTPN1 GDA SHANK2 CLTC CD44 PRKCZ CTNND1 GAB1	4.58e-05	617	130	14	int:AKT1
Interaction	BAG2 interactions	KIF13B MAP1B MYO10 BCORL1 LRRK1 ZFC3H1 CBL WNK1 VIRMA GTF2F1 ARHGEF10 CLTC SIK2 PRKCZ	5.00e-05	622	130	14	int:BAG2
Interaction	SALL1 interactions	ATRX VIRMA MTA1 NFIX CPSF1 PPP1R9B	5.21e-05	102	130	6	int:SALL1
Interaction	YWHAE interactions	KIF13B TICRR AKAP8 MAP1B ZC3H18 GIT2 RB1CC1 CBL WNK1 REEP3 VIRMA PACS1 WWC2 TIAM1 CLTC SIK2 PPP1R9B RPGR CTNND1 FGD6 GAB1	5.29e-05	1256	130	21	int:YWHAE
Interaction	EZR interactions	ANK3 CBL ITGB1 VIRMA PPL CD44 PPP1R9B PRKCZ CTNND1 UTRN SDC2 GAB1 WDR44	6.07e-05	553	130	13	int:EZR
Interaction	VIM interactions	MAP1B NSF RNF113A ZC3H18 RB1CC1 XRCC4 ASB15 TEX9 CBL VIRMA PPL MTA1 NFIX CLTC PPP1R9B PRKCZ	6.17e-05	804	130	16	int:VIM
Interaction	ACTN1 interactions	GIT2 XRCC4 CBL ITGB1 VIRMA PTPN1 CLTC SIK2 PPP1R9B MOB4	7.46e-05	341	130	10	int:ACTN1
Interaction	PLK2 interactions	NSF VIRMA CLTC CSTF1 FGD6	8.94e-05	70	130	5	int:PLK2
Interaction	SHANK3 interactions	ANK3 MAP1B PACSIN1 PSMD4 VIRMA ZNF263 SH3PXD2B SHANK2 XIRP2 PPP1R9B ZFHX3 AGAP7P	9.00e-05	496	130	12	int:SHANK3
Interaction	YWHAZ interactions	KIF13B TICRR AKAP8 NSF ZC3H18 RB1CC1 CBL WNK1 REEP3 VIRMA PACS1 WWC2 TIAM1 PRCC CLTC SIK2 PPP1R9B PRKCZ CTNND1 FGD6 GAB1	1.06e-04	1319	130	21	int:YWHAZ
Interaction	TECR interactions	MAP1B RNF113A ZC3H18 RB1CC1 VIRMA PTPN1 CLTC PRKCZ ATP5F1C	1.13e-04	290	130	9	int:TECR
Interaction	PDGFRB interactions	PDGFRA CBL VIRMA PTPN1 ARHGEF10 CLTC FGD6 GAB1	1.18e-04	228	130	8	int:PDGFRB
Interaction	CAVIN1 interactions	AKAP8 MAP1B MYO10 GIT2 XRCC4 ZBTB7B PTPN1 PRKCZ UTRN	1.19e-04	292	130	9	int:CAVIN1
Interaction	ITGB3 interactions	TPR MAP1B PDGFRA MYO10 CBL ITGB1 CLTC	1.19e-04	170	130	7	int:ITGB3
Interaction	PLEKHA7 interactions	MAGI1 KIF13B VIRMA PPL TIAM1 CTNND1	1.23e-04	119	130	6	int:PLEKHA7
Interaction	PTK2B interactions	RB1CC1 ZBTB7B CBL ITGB1 VIRMA GDA	1.23e-04	119	130	6	int:PTK2B
Interaction	FTH1 interactions	SPP1 PACSIN1 ASB15 VIRMA PPL GDA PIPSL	1.37e-04	174	130	7	int:FTH1
Interaction	ACTG1 interactions	TPR MYO10 RNF113A ZC3H18 ACTL6A GIT2 CLTC PPP1R9B CTNND1 KAT14 RNF138 WDR44	1.40e-04	520	130	12	int:ACTG1
Interaction	ATP6V1B2 interactions	ATRX CBL VIRMA PTPN1 INTS2 CLTC PPP1R9B ATP5F1C	1.59e-04	238	130	8	int:ATP6V1B2
Interaction	CD44 interactions	PDGFRA SPP1 ITGB1 VIRMA TIAM1 CD44 GMEB1 PRKCZ	1.63e-04	239	130	8	int:CD44
Interaction	TOP1 interactions	TPR AKAP8 PDGFRA ZC3H18 ACTL6A ZBTB7B VIRMA ZNF263 GTF2F1 MTA1 TIAM1 INTS2 CSTF1 CPSF1	1.64e-04	696	130	14	int:TOP1
Interaction	MT-ATP8 interactions	PACSIN1 FPR2 WNK1 ATP5F1C	1.68e-04	43	130	4	int:MT-ATP8
Interaction	NRAS interactions	MAGI1 KIF13B NSF CBL ITGB1 MIER1 PTPN1 SLC7A1 NEO1 TIAM1 CD44 CTNND1 GAB1 WDR44	1.71e-04	699	130	14	int:NRAS
Interaction	PIP interactions	ZGRF1 ZDBF2 ZC3H18 KMT2E TIAM1 CTNND1 MOB4	1.75e-04	181	130	7	int:PIP
Interaction	TAF6 interactions	RNF113A PSMD4 ACTL6A WNK1 GTF2F1 NFIX TAF7L MOB4	1.93e-04	245	130	8	int:TAF6
Interaction	ITGB2 interactions	TPR MAP1B CYTH1 PSMD4 WNK1 SH3PXD2B	2.16e-04	132	130	6	int:ITGB2
Interaction	KSR1 interactions	MAGI1 KIF13B REEP3 VIRMA TIAM1 FGD6	2.16e-04	132	130	6	int:KSR1
Interaction	CSNK2A2 interactions	ATRX SPP1 RNF113A BCORL1 ZC3H18 GIT2 ZFC3H1 ZBTB7B VIRMA PTPN1 MTA1 CLTC SDC2 KIF2C	2.25e-04	718	130	14	int:CSNK2A2
Interaction	CAV1 interactions	MAGI1 KIF13B ANK3 PDGFRA ITGB1 VIRMA PTPN1 NEO1 TIAM1 CLTC CD44 CTNND1 UTRN GAB1	2.45e-04	724	130	14	int:CAV1
Interaction	SYNPO interactions	MAGI1 RB1CC1 VIRMA PPL CLTC CD44 PPP1R9B	2.51e-04	192	130	7	int:SYNPO
Interaction	MAU2 interactions	AKAP8 ZDBF2 ACTL6A MED13L INTS2 CLTC	2.54e-04	136	130	6	int:MAU2
Interaction	ACTN4 interactions	MAGI1 ITGB1 VIRMA NFIX CLTC SIK2 PPP1R9B PRKCZ UTRN MOB4	2.73e-04	400	130	10	int:ACTN4
Interaction	FLNA interactions	ANK3 MAP1B ZGRF1 RNF113A CBL ITGB1 VIRMA PTPN1 CLTC CD44 SIK2 PPP1R9B PRKCZ	2.90e-04	648	130	13	int:FLNA
Interaction	TEC interactions	MAP1B LRRK1 IGSF9B CTNND1 GAB1	2.93e-04	90	130	5	int:TEC
Interaction	DENND4C interactions	MAGI1 KIF13B ZBTB7B VIRMA TIAM1 PIPSL	2.97e-04	140	130	6	int:DENND4C
Interaction	NCK2 interactions	BLNK GIT2 ZBTB7B CBL SH3PXD2B INTS2 SIK2 GAB1	3.04e-04	262	130	8	int:NCK2
Interaction	DIRAS3 interactions	ANK3 PSMD4 ITGB1 PTPN1 SLC7A1 TIAM1 CTNND1 GAB1	3.04e-04	262	130	8	int:DIRAS3
Interaction	VPS33B interactions	ANK3 TEX9 PTPN1 CLTC PPP1R9B CTNND1 MOB4	3.13e-04	199	130	7	int:VPS33B
Interaction	XRCC6 interactions	TPR ATRX MAP1B RNF113A NVL PSMD4 ZC3H18 XRCC4 ZBTB7B CBL VIRMA ZNF263 GTF2F1 MTA1 CLTC ZFHX3	3.18e-04	928	130	16	int:XRCC6
Interaction	CTDSPL interactions	ANK3 PACS1 TIAM1 CD44 CTNND1	3.25e-04	92	130	5	int:CTDSPL
Interaction	CCT6A interactions	MAP1B KDM5A ZC3H18 ACTL6A LRRK1 VIRMA PTPN1 CLTC PRKCZ UTRN MOB4 ATP5F1C	3.25e-04	570	130	12	int:CCT6A
Interaction	SEMA3C interactions	PDGFRA RNF113A VIRMA SDC2	3.27e-04	51	130	4	int:SEMA3C
Interaction	ANK3 interactions	ANK3 PDGFRA TIAM1 SCN2A PPP1R9B CTNND1 UTRN	3.32e-04	201	130	7	int:ANK3
Interaction	TRPS1 interactions	RNF113A ZBTB7B VIRMA MTA1 NFIX ZFHX3	3.33e-04	143	130	6	int:TRPS1
Interaction	AGRN interactions	ANK3 MAP1B PDGFRA SPP1 PSMD4 ZBTB7B VIRMA CLTC	3.45e-04	267	130	8	int:AGRN
Interaction	ZNF148 interactions	ACTR5 JADE1 ZBTB7B VIRMA NFIX CPSF1	3.46e-04	144	130	6	int:ZNF148
Interaction	PSMA5 interactions	MAP1B PSMD4 RB1CC1 ZBTB7B VIRMA PPL PTPN1 MOB4 KIF2C	3.59e-04	339	130	9	int:PSMA5
Interaction	MYH9 interactions	KIF13B MAP1B RNF113A PSMD4 ZC3H18 CBL WNK1 ITGB1 VIRMA SCN2A CLTC CD44 SIK2 PPP1R9B	3.70e-04	754	130	14	int:MYH9
Interaction	PHF21A interactions	TPR ZGRF1 BCORL1 ZDBF2 GIT2 RB1CC1 ZFHX3 UTRN KAT14	3.91e-04	343	130	9	int:PHF21A
Interaction	NEK4 interactions	MAP1B PDGFRA ZGRF1 ACTL6A VIRMA TAF7L CLTC CPSF1 RPGR AGAP7P PIPSL ATP5F1C	3.92e-04	582	130	12	int:NEK4
Interaction	GJA1 interactions	ANK3 MAP1B PSMD4 ITGB1 PTPN1 TIAM1 ARHGEF10 CLTC PPP1R9B CTNND1 UTRN GAB1	3.98e-04	583	130	12	int:GJA1
Interaction	ARF6 interactions	KIF13B ANK3 CYTH1 ITGB1 PTPN1 SLC7A1 TIAM1 CLTC CD44 ZFHX3 CTNND1 ATP5F1C	4.04e-04	584	130	12	int:ARF6
Interaction	ARRDC2 interactions	MAP1B PSMD4 CPSF1 PIPSL	4.07e-04	54	130	4	int:ARRDC2
Interaction	KDM7A interactions	BCL6 VIRMA	4.08e-04	5	130	2	int:KDM7A
Interaction	TMPO interactions	ATRX RNF113A ZDBF2 ZC3H18 JADE1 RB1CC1 ZBTB7B CBL ITGB1 VIRMA PTPN1 CLTC SDC2 RNF138	4.11e-04	762	130	14	int:TMPO
Interaction	ERBB2 interactions	PDGFRA SPP1 BLNK CBL ITGB1 VIRMA PTPRT RIN2 CLTC CD44 GAB1 ATP5F1C	4.36e-04	589	130	12	int:ERBB2
Interaction	CRTC3 interactions	KIF13B RNF113A CLTC SIK2	4.37e-04	55	130	4	int:CRTC3
Interaction	IQGAP1 interactions	MAP1B RNF113A ZC3H18 CBL ITGB1 VIRMA CLTC CD44 SIK2 PPP1R9B MOB4 ATP5F1C	4.49e-04	591	130	12	int:IQGAP1
Interaction	VAV2 interactions	CBL VIRMA CD44 CTNND1 GAB1	4.55e-04	99	130	5	int:VAV2
Interaction	STX4 interactions	ANK3 NSF ITGB1 PTPN1 SLC7A1 NEO1 CTNND1 UTRN GAB1 WDR44	4.65e-04	428	130	10	int:STX4
Interaction	TTLL4 interactions	ANK3 VIRMA PIPSL	4.81e-04	24	130	3	int:TTLL4
Interaction	RAC1 interactions	MAGI1 ANK3 GIT2 RB1CC1 ITGB1 PACS1 PTPN1 SLC7A1 TIAM1 ARHGEF10 CLTC CD44 PPP1R9B CTNND1 UTRN SDC2 GAB1	4.87e-04	1063	130	17	int:RAC1
Interaction	GRIN1 interactions	NSF SHANK2 TIAM1 CLTC PPP1R9B CTNND1	4.94e-04	154	130	6	int:GRIN1
GeneFamily	Ankyrin repeat domain containing	ANK3 BCORL1 GIT2 ASB15 SHANK2 ANKRD12 AGAP7P	3.47e-04	242	98	7	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MYO10 CYTH1 TIAM1 AGAP7P FGD6 GAB1	8.97e-04	206	98	6	682
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	TPR CDO1 ATRX MAP1B KDM5A PEG3 CBL MYBL1	6.76e-08	107	131	8	MM947
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	TPR CDO1 ATRX MAP1B KDM5A PEG3 CBL MYBL1	7.81e-08	109	131	8	M2451
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	ANK3 ATRX MAP1B CYTH1 PEG3 NAP1L3 MED13L RB1CC1 KMT2E PTPRT PACS1 SHANK2 CLVS2 NFIX SCN2A ZFHX3 CACNA1G IGSF9B ANKRD12 PRKCZ SVOP	1.41e-07	1106	131	21	M39071
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ATRX MAP1B KDM5A MYO10 CYTH1 NVL MED13L RB1CC1 XRCC4 PTPN1 SLC7A1 TIAM1 ARHGEF10 RIN2 ZFHX3 RPGR MOB4 MYBL1	2.78e-07	856	131	18	M4500
Coexpression	ENK_UV_RESPONSE_KERATINOCYTE_DN	TPR ATRX KDM5A MYO10 ACTL6A BCL6 GCSH WNK1 PTPN1 CLTC CD44 CD58 RPGR	9.26e-07	481	131	13	M3898
Coexpression	MASSARWEH_TAMOXIFEN_RESISTANCE_UP	ANK3 PDGFRA PACSIN1 BLNK NVL BCL6 SHANK2 NFIX RIN2 PWWP3B CTNND1 FGD6 UTRN GAB1	1.40e-06	583	131	14	M17454
Coexpression	MCBRYAN_PUBERTAL_BREAST_5_6WK_DN	TPR KDM5A CYTH1 ZBTB7B WNK1 NFIX ZFHX3	4.89e-06	133	131	7	M8880
Coexpression	MCBRYAN_PUBERTAL_BREAST_5_6WK_DN	TPR KDM5A CYTH1 ZBTB7B WNK1 NFIX ZFHX3	5.95e-06	137	131	7	MM990
Coexpression	GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN	ERICH1 AEN AKAP8 MAP1B RB1CC1 PRODH2 GTF2F1 CLTC	7.20e-06	198	131	8	M7701
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	ANK3 MAP1B RNF113A NAP1L3 CTXN2 CLVS2 NFIX SCN2A ZFHX3 ANKRD12 PRKCZ SVOP	9.34e-06	506	131	12	M39067
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	ATRX MAP1B KDM5A MYO10 NVL MED13L XRCC4 SLC7A1 TIAM1 RPGR MYBL1	2.33e-05	466	131	11	M13522
Coexpression	ZHONG_PFC_C3_MICROGLIA	ANK3 MAP1B NAP1L3 GCSH GDA NEO1 SHANK2 CLVS2 NFIX ZFR2 SCN2A	3.55e-05	488	131	11	M39104
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5	KIF13B ANK3 BLNK USP16 SHANK2 RIN2 CLTC ZFHX3 CTNND1 UTRN GAB1	3.75e-05	491	131	11	M13661
Coexpression	LAKE_ADULT_KIDNEY_C25_ENDOTHELIAL_CELLS_UNASSIGNED	ZFC3H1 KMT2E ZFHX3 UTRN	3.86e-05	38	131	4	M39244
Coexpression	DURCHDEWALD_SKIN_CARCINOGENESIS_DN	ANK3 NVL GIT2 ITGB1 PRCC CD44 CTNND1 UTRN	5.82e-05	265	131	8	M1684
Coexpression	GSE11924_TH1_VS_TH17_CD4_TCELL_DN	JADE1 ZFC3H1 ZBTB14 PTPN1 SETDB2 TIAM1 SIK2	6.60e-05	199	131	7	M3163
Coexpression	GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP	CYTH1 JADE1 BCL6 PACS1 GTF2F1 ANKRD12 PRKCZ	6.81e-05	200	131	7	M4588
Coexpression	DURCHDEWALD_SKIN_CARCINOGENESIS_DN	ANK3 NVL GIT2 ITGB1 PRCC CD44 CTNND1 UTRN	6.98e-05	272	131	8	MM1027
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	ERICH1 MAGI1 PEG3 ZIM2 GIT2 MED13L ITGB1 SLC7A1 ARHGEF10 SDC2	7.74e-05	441	131	10	M172
Coexpression	ZHAN_MULTIPLE_MYELOMA_MS_UP	MAGI1 MYO10 NAP1L3 WWC2	1.15e-04	50	131	4	M19632
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	ATRX MAP1B SPP1 FPR2 NAP1L3 SLC7A1 MTA1 CPSF1 ZFHX3 SDC2	1.60e-04	482	131	10	M12144
Coexpression	RODRIGUES_NTN1_TARGETS_DN	MAGI1 ATRX CBL WNK1 PPL GDA	1.62e-04	161	131	6	M11857
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	MAP1B BCORL1 NVL ZDBF2 JADE1 XRCC4 TEX9 USP16 PROKR1 PTPN1 FLRT1 WDR44 KIF2C	2.60e-05	532	131	13	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	PDGFRA ZGRF1 PEG3 NAP1L3 ADGRV1 BMP5 NEO1 NFIX RIN2 CD44 ARHGAP28 ZFHX3 ANKRD12 PWWP3B KAT14 GAB1	3.01e-05	791	131	16	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500	MAGI1 CDO1 PDGFRA SPP1 PEG3 NEO1 RIN2 TAF7L PPP1R9B CTNND1 MYBL1	7.75e-05	432	131	11	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	ATRX KDM5A PEG3 RB1CC1 KMT2E SETDB2 INTS2 TAF7L CD44 GMEB1 ANKRD12 RPGR UTRN WDR44 MYBL1	9.01e-05	776	131	15	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	ATRX KDM5A PEG3 RB1CC1 KMT2E WNK1 INTS2 TAF7L CD44 GMEB1 ANKRD12 RPGR UTRN WDR44 MYBL1	9.28e-05	778	131	15	gudmap_developingGonad_e18.5_ovary_1000
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX MYO10 PEG3 RB1CC1 ITGB1 MIER1 SAMD9L ANKRD12 UTRN	3.48e-10	194	132	10	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MAP1B NSF PACSIN1 PEG3 ZDBF2 CTXN2 CLVS2 SCN2A SVOP	4.76e-09	186	132	9	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TPR ATRX MAP1B JADE1 RB1CC1 KMT2E USP16 ANKRD12 UTRN	8.58e-09	199	132	9	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TPR ATRX CYTH1 ZFC3H1 MED13L KMT2E SAMD9L ANKRD12 UTRN	8.96e-09	200	132	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAP1B NSF PACSIN1 PEG3 CLVS2 SCN2A SVOP CDH7	1.16e-07	193	132	8	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATRX MAP1B NSF PACSIN1 CLVS2 SCN2A ANKRD12 SVOP	1.16e-07	193	132	8	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MAP1B NSF PACSIN1 RB1CC1 CLVS2 SCN2A ANKRD12 SVOP	1.21e-07	194	132	8	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 ZNF69 PRKCZ	7.70e-07	170	132	7	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR KIF13B ATRX PEG3 ITGB1 XIRP2 RIN2	9.71e-07	176	132	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR KIF13B ATRX MYO10 MIER1 SAMD9L UTRN	1.05e-06	178	132	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 WWC2 SHANK2 PRKCZ CTNND1 UTRN GAB1	1.31e-06	184	132	7	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 WWC2 SHANK2 PRKCZ CTNND1 UTRN GAB1	1.31e-06	184	132	7	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MAP1B PEG3 ZDBF2 CTXN2 SCN2A PWWP3B SVOP	1.51e-06	188	132	7	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ CTNND1	1.51e-06	188	132	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPP1 FPR2 GDA SH3PXD2B CLTC CD44 PNPLA7	1.56e-06	189	132	7	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CDO1 MAP1B PDGFRA MYO10 BMP5 KCNG1 ARHGAP28	1.62e-06	190	132	7	81f8f2cddf4c51b879f315260cd1fca80355a371
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic-stroma-muscle\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CDO1 MAP1B PDGFRA MYO10 BMP5 KCNG1 ARHGAP28	1.62e-06	190	132	7	20106e5213f6a7560554b8b4f84b23c5554ba975
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPP1 FPR2 GDA SH3PXD2B CLTC CD44 PNPLA7	1.62e-06	190	132	7	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CDO1 MAP1B PDGFRA MYO10 BMP5 KCNG1 ARHGAP28	1.62e-06	190	132	7	877b544decf302e0d41be23dffa1861f79c70914
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B ATRX MAP1B PDGFRA PEG3 NFIX SDC2	1.68e-06	191	132	7	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	KDM5A ZFC3H1 MED13L RB1CC1 KMT2E WNK1 UTRN	1.74e-06	192	132	7	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MAP1B PACSIN1 ZDBF2 SHANK2 SCN2A ANKRD12 SVOP	1.74e-06	192	132	7	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	KDM5A ZFC3H1 MED13L RB1CC1 KMT2E WNK1 UTRN	1.80e-06	193	132	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ CTNND1	1.86e-06	194	132	7	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ CTNND1	1.92e-06	195	132	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 PEG3 ITGB1 PPL BMP5 CLTC SDC2	1.92e-06	195	132	7	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MAP1B NSF PACSIN1 PEG3 SCN2A ANKRD12 SVOP	2.20e-06	199	132	7	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PACSIN1 NAP1L3 PTPRT SHANK2 SCN2A PRKCZ SVOP	2.28e-06	200	132	7	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	MAP1B NSF PACSIN1 CTXN2 SCN2A ANKRD12 SVOP	2.28e-06	200	132	7	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	CDO1 SPP1 MYO10 ADGRV1 GCSH CD58 SDC2	2.28e-06	200	132	7	4477591efada4007bab1f689017e3ac285267d29
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PACSIN1 NAP1L3 PTPRT SHANK2 SCN2A PRKCZ SVOP	2.28e-06	200	132	7	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PACSIN1 NAP1L3 PTPRT SHANK2 SCN2A PRKCZ SVOP	2.28e-06	200	132	7	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Radial_glial-RG\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	CDO1 SPP1 MYO10 GCSH CD44 CD58 SDC2	2.28e-06	200	132	7	fb7c9c0e4beadad6e41e68f6f889e56650898d22
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Radial_glial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	CDO1 SPP1 MYO10 GCSH CD44 CD58 SDC2	2.28e-06	200	132	7	fff209256805a448393c385b79a70c2e2172e49c
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SPP1 BCORL1 RB1CC1 CBL GMEB1 CACNA1G	4.55e-06	144	132	6	5e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDO1 ANK3 PDGFRA NAP1L3 GCSH SLC7A1	6.21e-06	152	132	6	6aad62b5b5ad2f78c6600f37960338d40628a439
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR SPP1 FPR2 GDA CD44 PNPLA7	8.94e-06	162	132	6	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 SPP1 PEG3 ZDBF2 ZFR2 MYBL1	1.14e-05	169	132	6	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	1.18e-05	170	132	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CDO1 NAP1L3 BMP5 FAM153B KCNG1 CACNA1G	1.43e-05	176	132	6	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CDO1 NAP1L3 BMP5 FAM153B KCNG1 CACNA1G	1.43e-05	176	132	6	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 KIF13B ANK3 ADGRV1 SHANK2 PRKCZ	1.53e-05	178	132	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	1.58e-05	179	132	6	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRMT9B LRRK1 PTPRT FGD6 UTRN CDH7	1.63e-05	180	132	6	8923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 MYO10 CYTH1 ITGB1 SAMD9L UTRN	1.68e-05	181	132	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPL PTPN1 WWC2 SHANK2 PRKCZ UTRN	1.68e-05	181	132	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	PACSIN1 PEG3 SH3PXD2B NEO1 CD44 ZFHX3	1.68e-05	181	132	6	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX ITGB1 MIER1 SAMD9L UTRN	1.73e-05	182	132	6	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX ITGB1 MIER1 SAMD9L UTRN	1.73e-05	182	132	6	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TOPAZ1 ADGRV1 MED13L SCN2A PPP1R9B ZFHX3	1.96e-05	186	132	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPL PTPN1 WWC2 SHANK2 PRKCZ UTRN	1.96e-05	186	132	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MAP1B PACSIN1 PEG3 ZDBF2 CTXN2 SVOP	1.96e-05	186	132	6	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 ATRX MYO10 ITGB1 SAMD9L UTRN	1.96e-05	186	132	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 ANK3 ADGRV1 PPL SHANK2 PRKCZ	1.96e-05	186	132	6	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 ADGRV1 PPL WWC2 SHANK2 PRKCZ	2.02e-05	187	132	6	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	TRMT9B MAGI1 KIF13B MYO10 TIAM1 SDC2	2.02e-05	187	132	6	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 JADE1 PPL WWC2 SHANK2 PRKCZ	2.08e-05	188	132	6	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PDGFRA BMP5 NEO1 NFIX CACNA1G SDC2	2.08e-05	188	132	6	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NSF PACSIN1 ZDBF2 SCN2A ANKRD12 SVOP	2.21e-05	190	132	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATRX MAP1B JADE1 KMT2E ITGB1 UTRN	2.21e-05	190	132	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 BCL6 WNK1 ITGB1 RIN2 CLTC	2.21e-05	190	132	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 KIF13B ANK3 BLNK SHANK2 SCN2A	2.27e-05	191	132	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX RB1CC1 ITGB1 MIER1 SAMD9L	2.27e-05	191	132	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANK3 VTCN1 ADGRV1 SHANK2 PWWP3B	2.27e-05	191	132	6	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	2.27e-05	191	132	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	2.27e-05	191	132	6	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MAP1B ZDBF2 SCN2A ANKRD12 SVOP CDH7	2.27e-05	191	132	6	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	2.27e-05	191	132	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MAP1B ZDBF2 SCN2A ANKRD12 SVOP CDH7	2.27e-05	191	132	6	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX RB1CC1 ITGB1 MIER1 SAMD9L	2.27e-05	191	132	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ATRX RB1CC1 ITGB1 MIER1 SAMD9L	2.27e-05	191	132	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	2.34e-05	192	132	6	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 ANK3 ADGRV1 WWC2 SHANK2 PRKCZ	2.34e-05	192	132	6	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADGRV1 PPL SLC7A1 SHANK2 PRKCZ PWWP3B	2.34e-05	192	132	6	450baeb5c3df7a9445472530002ce38f177a333c
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX NSF PEG3 RIN2 ZFHX3 FGD6	2.34e-05	192	132	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	MAGI1 ANK3 VTCN1 ADGRV1 SHANK2 PWWP3B	2.41e-05	193	132	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	PND01\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDO1 PEG3 MED13L RB1CC1 RIN2 PWWP3B	2.41e-05	193	132	6	c291345c11cfcbceacbdc001a5851f67478a2779
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BLNK ZDBF2 DCST1 SCN2A PNPLA7 GAB1	2.48e-05	194	132	6	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 KIF13B ANK3 BLNK SHANK2 SCN2A	2.48e-05	194	132	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TICRR BLNK ADGRV1 SHANK2 MYBL1 KIF2C	2.48e-05	194	132	6	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	ANK3 CYTH1 ZBTB7B NEO1 CD44 ANKRD12	2.48e-05	194	132	6	4547b57669be5d4f0de55175802ee04372288a6a
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BLNK ADGRV1 PPL SHANK2 PRKCZ PWWP3B	2.48e-05	194	132	6	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	MAP1B ACTR5 SETDB2 TRNAU1AP UTRN WDR44	2.55e-05	195	132	6	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYO10 BMP5 NEO1 TIAM1 ARHGAP28 SDC2	2.55e-05	195	132	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	BLOOD--(1)_T_cell-(1)_EM_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	REEP3 ITGB1 TIAM1 CD44 CD58 ANKRD12	2.55e-05	195	132	6	4b8831ed8fb73579f49604eeda8a3b2344e69f0e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B ATRX MAP1B BMP5 NFIX SDC2	2.55e-05	195	132	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ANK3 ADGRV1 MED13L SHANK2 GAB1	2.63e-05	196	132	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 ANK3 BLNK PPL SHANK2 SCN2A	2.63e-05	196	132	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP1B PDGFRA JADE1 ITGB1 CD44 SDC2	2.63e-05	196	132	6	e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP1B PDGFRA JADE1 ITGB1 CD44 SDC2	2.63e-05	196	132	6	f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPP1 SLC7A1 SHANK2 SCN2A CD44	2.70e-05	197	132	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 ZDBF2 ZFC3H1 ANKRD12 UTRN MYBL1	2.70e-05	197	132	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B PTPRT CLVS2 ZFR2 SCN2A SVOP	2.70e-05	197	132	6	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	KIF13B ANK3 BMP5 SH3PXD2B NEO1 ARHGAP28	2.70e-05	197	132	6	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CDO1 MAP1B PDGFRA ARHGEF10 NFIX SDC2	2.78e-05	198	132	6	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	PDGFRA SPP1 MYO10 ADGRV1 CD44 CD58	2.78e-05	198	132	6	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDO1 MAP1B PDGFRA JADE1 BCL6 SDC2	2.78e-05	198	132	6	abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-oRG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CDO1 MYO10 ADGRV1 REEP3 CD58 SDC2	2.78e-05	198	132	6	72dc49aa107d0cc6206eb67b577c73e190855125
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	PPL PTPN1 WWC2 SHANK2 PRKCZ UTRN	2.78e-05	198	132	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ANK3 ADGRV1 MED13L SHANK2 GAB1	2.78e-05	198	132	6	1996373bdccc55aac347d349bd22f6aad6d0c668
Drug	rofecoxib; Down 200; 10uM; HL60; HG-U133A	ANK3 GIT2 CBL WNK1 SLC7A1 GTF2F1 TRNAU1AP CD44 SDC2	2.16e-06	197	131	9	371_DN
Drug	Harmine hydrochloride [343-27-1]; Up 200; 16uM; HL60; HG-U133A	TPR KDM5A SPP1 PACSIN1 SETD6 RB1CC1 GTF2F1 CTNND1 SDC2	2.16e-06	197	131	9	1758_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	AKAP8 PEG3 JADE1 XRCC4 ZBTB14 SLC7A1 RIN2 CD58	7.71e-06	174	131	8	5745_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A	TPR ATRX MAP1B MYO10 WNK1 PACS1 GTF2F1 NFIX	1.41e-05	189	131	8	4271_DN
Drug	Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A	TPR MAP1B MYO10 WNK1 SLC7A1 WWC2 GTF2F1 NFIX	1.46e-05	190	131	8	4306_DN
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A	TPR ATRX MAP1B MYO10 WNK1 SLC7A1 NFIX FGD6	1.52e-05	191	131	8	4303_DN
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A MYO10 CBL WNK1 SLC7A1 WWC2	1.52e-05	191	131	8	4279_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A MYO10 WNK1 GTF2F1 NFIX CDH7	1.52e-05	191	131	8	4283_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	TPR ANK3 MAP1B MYO10 WNK1 PACS1 GTF2F1 NFIX	1.64e-05	193	131	8	4321_DN
Drug	lomustine; Down 200; 100uM; MCF7; HT_HG-U133A	MAGI1 ANK3 ACTR5 BCORL1 ZBTB14 SIK2 ANKRD12 UTRN	1.70e-05	194	131	8	7089_DN
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	ANK3 SETD6 WNK1 ZBTB14 SLC7A1 SHANK2 KCNG1 ARHGAP28	1.77e-05	195	131	8	7539_DN
Drug	Trichlormethiazide [133-67-5]; Down 200; 10.6uM; PC3; HT_HG-U133A	TRMT9B LRRK1 PPL PACS1 MTA1 TIAM1 ARHGEF10 ZFHX3	1.77e-05	195	131	8	4198_DN
Drug	Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; HL60; HT_HG-U133A	TRMT9B AEN LRRK1 XRCC4 SLC7A1 KCNG1 RIN2 CTNND1	1.83e-05	196	131	8	2537_DN
Drug	Dipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A ITGB1 PPL WWC2 RPGR CTNND1	1.83e-05	196	131	8	7124_DN
Drug	Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A	TPR GIT2 JADE1 TIAM1 KCNG1 CPSF1 ANKRD12 SDC2	1.90e-05	197	131	8	6212_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	TPR AEN ATRX KDM5A WNK1 WWC2 GTF2F1 NFIX	1.90e-05	197	131	8	4266_DN
Drug	5286656; Down 200; 50uM; MCF7; HT_HG-U133A_EA	ANK3 BCL6 GTF2F1 MTA1 KCNG1 CD44 RPGR GAB1	1.97e-05	198	131	8	889_DN
Drug	Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A	TPR MAP1B XRCC4 ITGB1 ZBTB14 MTA1 RIN2 RPGR	2.04e-05	199	131	8	3307_DN
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	KIF13B BCL6 XRCC4 CBL PACS1 BMP5 ARHGEF10 UTRN	2.04e-05	199	131	8	3349_DN
Drug	Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; HL60; HG-U133A	KDM5A CYTH1 WNK1 PTPRT CD44 CTNND1 SDC2	5.24e-05	167	131	7	1745_UP
Drug	HA100	ITGB1 MIER1 CD44	8.05e-05	15	131	3	CID000003545
Drug	BT-B	ANK3 MAP1B BCL6 ZBTB14 SETDB2 SCN2A ZFHX3 CTNND1	8.40e-05	243	131	8	CID000081462
Drug	vinylene	AKAP8 PEG3 ZIM2 ZBTB14 ZNF263 MTA1 RNF138 MYBL1	8.89e-05	245	131	8	CID000006326
Drug	salinomycin	SPP1 NSF MYO10 INTS2 RIN2 CLTC CSTF1	9.98e-05	185	131	7	ctd:C010327
Drug	NSC339663	MYO10 ACTL6A ITGB1 PPL SHANK2 CLTC PPP1R9B GAB1	1.02e-04	250	131	8	CID000003892
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; PC3; HT_HG-U133A	ACTR5 CYTH1 GIT2 RB1CC1 RPGR UTRN SDC2	1.03e-04	186	131	7	4578_DN
Drug	Dicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A	TPR ANK3 MYO10 WNK1 SLC7A1 GTF2F1 CDH7	1.07e-04	187	131	7	4323_DN
Drug	Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A MYO10 WNK1 GTF2F1 NFIX	1.14e-04	189	131	7	4304_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A XRCC4 TIAM1 GMEB1 UTRN	1.14e-04	189	131	7	3788_DN
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A	ANK3 ATRX MAP1B XRCC4 WNK1 ARHGAP28 UTRN	1.18e-04	190	131	7	4507_DN
Drug	Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	AEN GIT2 XRCC4 CBL CD44 GMEB1 WDR44	1.22e-04	191	131	7	7195_UP
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	TRMT9B ATRX KDM5A CBL WNK1 SLC7A1 TIAM1	1.22e-04	191	131	7	6020_DN
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	TPR AEN MAP1B GIT2 WNK1 WWC2 GTF2F1	1.22e-04	191	131	7	4273_DN
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	TPR ATRX MYO10 CBL WNK1 SLC7A1 CPSF1	1.22e-04	191	131	7	3926_DN
Drug	Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	MAP1B KDM5A BCL6 SHANK2 RIN2 SIK2 ANKRD12	1.22e-04	191	131	7	5327_UP
Drug	Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A	MAP1B XRCC4 ITGB1 KCNG1 GMEB1 RPGR FGD6	1.26e-04	192	131	7	5990_DN
Drug	Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MAGI1 XRCC4 WNK1 ITGB1 PACS1 MTA1 UTRN	1.26e-04	192	131	7	3318_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A MYO10 WNK1 GTF2F1 NFIX	1.26e-04	192	131	7	4311_DN
Drug	Tropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A	TPR MYO10 CYTH1 CBL WNK1 WWC2 GTF2F1	1.30e-04	193	131	7	4280_DN
Drug	Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A	TPR MAP1B GIT2 WNK1 GTF2F1 NFIX CSTF1	1.30e-04	193	131	7	4305_DN
Drug	Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; HL60; HG-U133A	TPR GIT2 WWC2 CD44 CD58 ANKRD12 SDC2	1.30e-04	193	131	7	1412_DN
Drug	Hycanthone [3105-97-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	MAP1B CYTH1 PACS1 BMP5 SLC7A1 RIN2 CD44	1.30e-04	193	131	7	3229_DN
Drug	Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	TPR KDM5A CYTH1 XRCC4 WNK1 GTF2F1 NFIX	1.34e-04	194	131	7	4281_DN
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A	ANK3 KDM5A BCORL1 ZBTB14 PACS1 SLC7A1 RIN2	1.34e-04	194	131	7	3303_DN
Drug	Androsterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A	GIT2 XRCC4 WNK1 ZBTB14 PACS1 WWC2 CD44	1.34e-04	194	131	7	5696_DN
Drug	Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	ATRX RNF113A BLNK SLC7A1 WWC2 CD44 ANKRD12	1.34e-04	194	131	7	3867_DN
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A	TPR ATRX KDM5A MYO10 NAP1L3 WNK1 GMEB1	1.34e-04	194	131	7	4309_DN
Drug	Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	KIF13B SPP1 BLNK ZIM2 SLC7A1 ANKRD12 UTRN	1.38e-04	195	131	7	4814_UP
Drug	Protriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; HL60; HT_HG-U133A	KDM5A MYO10 CYTH1 LRRK1 SLC7A1 KCNG1 CTNND1	1.38e-04	195	131	7	3119_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	TPR PDGFRA MED13L WNK1 SLC7A1 WWC2 ANKRD12	1.38e-04	195	131	7	6918_UP
Drug	Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A	MED13L CBL KCNG1 GMEB1 ANKRD12 SDC2 MYBL1	1.38e-04	195	131	7	6245_UP
Drug	5252917; Down 200; 14uM; MCF7; HT_HG-U133A_EA	ACTR5 GIT2 WNK1 ZBTB14 SIK2 ANKRD12 RPGR	1.38e-04	195	131	7	944_DN
Drug	Naringin hydrate [11032-30-7]; Down 200; 6.6uM; MCF7; HT_HG-U133A	TPR KDM5A SLC7A1 WWC2 MTA1 CD44 UTRN	1.38e-04	195	131	7	3286_DN
Drug	Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A	KDM5A CBL WNK1 PACS1 BMP5 GMEB1 UTRN	1.43e-04	196	131	7	7338_UP
Drug	Sulfaphenazole [526-08-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	KIF13B ACTR5 ARHGEF10 KCNG1 RIN2 CD44 SDC2	1.43e-04	196	131	7	1673_UP
Drug	Loxapine succinate [27833-64-3]; Down 200; 9uM; MCF7; HT_HG-U133A	AKAP8 ANK3 BCORL1 BMP5 CD44 GMEB1 CPSF1	1.43e-04	196	131	7	5293_DN
Drug	Debrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A	AKAP8 XRCC4 WNK1 PACS1 SLC7A1 MTA1 RPGR	1.43e-04	196	131	7	5288_UP
Drug	Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	TPR ZBTB14 MTA1 CD44 SIK2 RPGR SDC2	1.43e-04	196	131	7	1536_UP
Drug	Ronidazole [7681-76-7]; Up 200; 20uM; PC3; HT_HG-U133A	AEN PDGFRA PEG3 BCORL1 MTA1 KCNG1 ZFHX3	1.43e-04	196	131	7	7131_UP
Drug	Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; PC3; HT_HG-U133A	PEG3 LRRK1 PACS1 MTA1 TIAM1 ARHGAP28 ZFHX3	1.43e-04	196	131	7	4227_DN
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	MED13L ITGB1 MTA1 TIAM1 CD44 ANKRD12 RPGR	1.43e-04	196	131	7	2827_DN
Drug	Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	KDM5A MED13L WWC2 TIAM1 GMEB1 SIK2 MYBL1	1.43e-04	196	131	7	7408_UP
Drug	6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A	KDM5A LRRK1 MED13L RB1CC1 WNK1 SLC7A1 GMEB1	1.43e-04	196	131	7	2925_DN
Drug	Ergocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A	KIF13B AEN CBL BMP5 SLC7A1 MTA1 SIK2	1.43e-04	196	131	7	4374_DN
Drug	estradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A	TRMT9B AEN ANK3 XRCC4 MTA1 CACNA1G MYBL1	1.47e-04	197	131	7	2668_DN
Drug	Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ATRX KDM5A XRCC4 WNK1 SLC7A1 SIK2 ZFHX3	1.47e-04	197	131	7	2307_DN
Drug	Terconazole [67915-31-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	KDM5A PEG3 XRCC4 PPL SLC7A1 MTA1 ARHGEF10	1.47e-04	197	131	7	4583_DN
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	CYTH1 PEG3 LRRK1 ITGB1 PACS1 SLC7A1 TIAM1	1.47e-04	197	131	7	4666_DN
Drug	Bethanechol chloride [590-63-6]; Down 200; 20.4uM; PC3; HT_HG-U133A	ANK3 SETD6 CYTH1 LRRK1 CBL SLC7A1 UTRN	1.47e-04	197	131	7	5114_DN
Drug	Androsterone [53-41-8]; Up 200; 13.8uM; PC3; HT_HG-U133A	AEN MAP1B KDM5A BCL6 CBL MTA1 GMEB1	1.47e-04	197	131	7	4635_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; HL60; HG-U133A	AEN ATRX FPR2 NVL ACTL6A GIT2 MED13L	1.47e-04	197	131	7	1363_UP
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; PC3; HT_HG-U133A	PEG3 GIT2 SLC7A1 KCNG1 GMEB1 RPGR UTRN	1.47e-04	197	131	7	5090_DN
Drug	SC-58125; Up 200; 10uM; HL60; HG-U133A	KIF13B AEN BCL6 PTPRT NEO1 CD44 GMEB1	1.47e-04	197	131	7	542_UP
Drug	Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; PC3; HT_HG-U133A	CYTH1 LRRK1 ITGB1 SLC7A1 TIAM1 ARHGEF10 CACNA1G	1.47e-04	197	131	7	4673_DN
Drug	Niridazole [61-57-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	AKAP8 WNK1 ZBTB14 MTA1 TRNAU1AP KCNG1 RIN2	1.47e-04	197	131	7	3301_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	XRCC4 PACS1 BMP5 SLC7A1 TIAM1 KCNG1 FGD6	1.47e-04	197	131	7	6934_DN
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A	KDM5A BCORL1 WNK1 SLC7A1 MTA1 CD44 ZFHX3	1.47e-04	197	131	7	5685_DN
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A	KDM5A PACSIN1 SLC7A1 PRODH2 KCNG1 ARHGAP28 GAB1	1.47e-04	197	131	7	3717_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	PDGFRA KDM5A LRRK1 SLC7A1 SHANK2 ARHGEF10 GMEB1	1.47e-04	197	131	7	3996_DN
Drug	Lisinopril [83915-83-7]; Down 200; 9uM; HL60; HT_HG-U133A	AEN BCORL1 LRRK1 CBL MTA1 GMEB1 UTRN	1.47e-04	197	131	7	2371_DN
Drug	genistein; Down 200; 10uM; MCF7; HG-U133A	CBL WNK1 SLC7A1 PRODH2 ZFR2 UTRN SDC2	1.52e-04	198	131	7	382_DN
Drug	Probenecid [57-66-9]; Down 200; 14uM; PC3; HT_HG-U133A	LRRK1 SLC7A1 MTA1 TIAM1 ARHGEF10 KCNG1 GAB1	1.52e-04	198	131	7	4185_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A	TPR MAP1B KDM5A MYO10 WNK1 PACS1 NFIX	1.52e-04	198	131	7	4282_DN
Drug	5140203; Up 200; 15uM; MCF7; HT_HG-U133A_EA	MAGI1 ANK3 KDM5A XRCC4 WNK1 SLC7A1 GMEB1	1.52e-04	198	131	7	908_UP
Drug	Pinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A	ACTR5 GIT2 CBL ZBTB14 SLC7A1 ANKRD12 RPGR	1.52e-04	198	131	7	7437_UP
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	KIF13B JADE1 BCL6 RB1CC1 XRCC4 ZFHX3 UTRN	1.52e-04	198	131	7	1799_UP
Drug	Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	CDO1 PACSIN1 BLNK BCL6 CBL WNK1 SLC7A1	1.52e-04	198	131	7	2242_UP
Drug	Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; HL60; HG-U133A	SPP1 FPR2 GIT2 BCL6 MED13L CD44 WDR44	1.52e-04	198	131	7	1378_UP
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	ATRX MAP1B BLNK GIT2 GMEB1 ZFHX3 UTRN	1.52e-04	198	131	7	5405_DN
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A	RNF113A GIT2 JADE1 BCL6 CPSF1 ZFHX3 ANKRD12	1.52e-04	198	131	7	6228_DN
Drug	Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A	CYTH1 XRCC4 PACS1 SHANK2 KCNG1 UTRN GAB1	1.52e-04	198	131	7	4412_UP
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A	AKAP8 GIT2 SHANK2 ARHGEF10 KCNG1 CD44 SDC2	1.52e-04	198	131	7	6239_DN
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HG-U133A	KDM5A ZIM2 RB1CC1 WWC2 KCNG1 SIK2 FGD6	1.57e-04	199	131	7	1950_DN
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; HL60; HT_HG-U133A	TRMT9B PDGFRA ACTR5 PEG3 BCL6 PACS1 SHANK2	1.57e-04	199	131	7	2179_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	ACTR5 NEO1 MTA1 CD44 SIK2 RPGR SDC2	1.57e-04	199	131	7	5003_DN
Drug	Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A	BCORL1 GIT2 WNK1 KCNG1 CD44 FGD6 UTRN	1.57e-04	199	131	7	5988_DN
Drug	Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A	MAGI1 ATRX PACS1 BMP5 KCNG1 GMEB1 SIK2	1.62e-04	200	131	7	5474_DN
Drug	ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A	TRMT9B ANK3 XRCC4 SLC7A1 TRNAU1AP RIN2 CACNA1G	1.62e-04	200	131	7	2665_DN
Drug	Magnetite Nanoparticles	CDO1 ANK3 ATRX KDM5A SPP1 NVL JADE1 ZFC3H1 KMT2E REEP3 USP16 GDA SAMD9L NFIX CLTC CD44 ANKRD12 UTRN KAT14	1.81e-04	1310	131	19	ctd:D058185
Drug	2-(9-anthroyloxy)stearic acid	SCN2A CLTC	1.96e-04	4	131	2	CID000132860
Disease	Intellectual Disability	MAP1B KDM5A NSF RNF113A ACTL6A MED13L KMT2E PACS1 SHANK2 CACNA1G	2.49e-05	447	127	10	C3714756
Disease	Adenoid Cystic Carcinoma	MAGI1 ATRX BCORL1 ZIM2 MYBL1	7.41e-05	100	127	5	C0010606
Disease	cortical surface area measurement	MAGI1 TICRR ANK3 NSF ADGRV1 MED13L REEP3 PTPN1 ZNF469 NEO1 NFIX PPP1R9B ARHGAP28 ZFHX3 PRKCZ FGD6	2.21e-04	1345	127	16	EFO_0010736
Disease	Bipolar Disorder	MAGI1 ANK3 PACS1 SHANK2 ARHGEF10 NFIX SCN2A PRKCZ CDH7	2.30e-04	477	127	9	C0005586
Disease	Manic Disorder	ANK3 PACS1 SHANK2 SCN2A	2.54e-04	71	127	4	C0024713
Disease	Manic	ANK3 PACS1 SHANK2 SCN2A	3.65e-04	78	127	4	C0338831
Disease	MiT family translocation renal cell carcinoma	PRCC CLTC	3.81e-04	7	127	2	C4518356
Disease	Depression, Bipolar	ANK3 PACS1 SHANK2 SCN2A	3.83e-04	79	127	4	C0005587
Disease	Growth Disorders	ATRX CBL SH3PXD2B	5.01e-04	36	127	3	C0018273
Disease	Abdominal Cryptorchidism	ATRX CBL	5.06e-04	8	127	2	C1563730
Disease	Inguinal Cryptorchidism	ATRX CBL	5.06e-04	8	127	2	C1563731
Disease	Bilateral Cryptorchidism	ATRX CBL	5.06e-04	8	127	2	C0431663
Disease	Unilateral Cryptorchidism	ATRX CBL	5.06e-04	8	127	2	C0431664
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5A SHANK2 ARHGEF10 SCN2A CTNND1	5.21e-04	152	127	5	DOID:0060041 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN2A	6.49e-04	9	127	2	C3502809
Disease	Cryptorchidism	ATRX CBL	8.09e-04	10	127	2	C0010417
Disease	Fetal Alcohol Spectrum Disorders	ANK3 PDGFRA	1.39e-03	13	127	2	C2985290
Disease	Obesity	ZBTB7B PACS1 PTPN1 ZFR2 ZFHX3	1.98e-03	205	127	5	C0028754
Disease	lung small cell carcinoma (is_marker_for)	ATRX ITGB1	2.12e-03	16	127	2	DOID:5409 (is_marker_for)
Disease	Abnormality of chromosome segregation	ERICH1 MYO10 ZBTB14	2.23e-03	60	127	3	HP_0002916
Disease	MAJOR AFFECTIVE DISORDER 2	MAGI1 PRKCZ	2.40e-03	17	127	2	C1839839
Disease	Fetal Alcohol Syndrome	ANK3 PDGFRA	2.40e-03	17	127	2	C0015923
Disease	Abnormality of refraction	ANK3 KDM5A ZBTB7B CLVS2 NFIX SCN2A ZFHX3 UTRN SDC2	2.59e-03	673	127	9	HP_0000539
Disease	Profound Mental Retardation	KDM5A MED13L SHANK2 CACNA1G	3.12e-03	139	127	4	C0020796
Disease	Mental Retardation, Psychosocial	KDM5A MED13L SHANK2 CACNA1G	3.12e-03	139	127	4	C0025363
Disease	Mental deficiency	KDM5A MED13L SHANK2 CACNA1G	3.12e-03	139	127	4	C0917816
Disease	bipolar I disorder	ANK3 PACS1 SHANK2 KCNG1	3.28e-03	141	127	4	EFO_0009963
Disease	Colorectal Carcinoma	ERICH1 CDO1 MAP1B PEG3 WNK1 PTPRT TIAM1 PRKCZ CDH7	3.42e-03	702	127	9	C0009402
Disease	Malignant Glioma	ATRX SPP1 MYBL1	3.45e-03	70	127	3	C0555198
Disease	mixed gliomas	ATRX SPP1 MYBL1	3.45e-03	70	127	3	C0259783

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDREPDSSTDMEQYM	AEN	286	Q8WTP8
VSFMYQPEDSSNEGE	ERICH1	186	Q86X53
EQPDYDMDSEDETLL	EPC2	111	Q52LR7
NSDSEPDEMIYDDVE	ARHGEF10	246	O15013
FTSETVDPEMEGDDN	AKAP8	546	O43823
DSTYDEQVAAQMPTV	ACTL6A	271	O96019
DSDMGSQEVFPTEEE	BCORL1	1241	Q5H9F3
VMIDESLSSDDPDSY	ADGRV1	4041	Q8WXG9
MDTNDDPDEDHLTSY	ASB15	1	Q8WXK1
STPESDYDNTPNDME	GIT2	586	Q14161
VESMNDFDPLFSEET	ACTR5	406	Q9H9F9
PVEYDSDFMLESSES	ANKRD12	1226	Q6UB98
HYDMSDTNSDPEVVN	C18orf25	246	Q96B23
MEDPTQPDYEATSQS	PRODH2	396	Q9UF12
YPDATDEDITSHMES	SPP1	181	P10451
ECSTDEVNSEDMDAY	ITGB1	501	P05556
SDDDSSMEDYPDPQS	NVL	101	O15381
SWQYPMSEEESSDVE	PDGFRA	56	P16234
ESPESDFMSAVNEFV	RB1CC1	726	Q8TDY2
AAPYGIESMSQDTEV	PTPN1	356	P18031
IDDSEMESPVDDVFY	NFIX	281	Q14938
TSSDEDEYEMESPNI	CD58	96	P19256
EVDYSPSDMQDSSLS	MAP1B	1686	P46821
MEEPSYTQDNDLSEL	MAP1B	1706	P46821
MVDPFTYAAEEDSTS	MED13L	1681	Q71F56
EDDVPEMNSSFTADS	MAGI1	241	Q96QZ7
DTGTIEANEDMEIAY	GMEB1	81	Q9Y692
TDPSEKSEDVQYFDM	LRRK1	1176	Q38SD2
GSVSSEELDENYVPM	GAB1	436	Q13480
METNFSTPLNEYEEV	FPR2	1	P25090
TSPTVDDEEEMLYGD	CPSF1	736	Q10570
SYEPQETDSLSQMET	PPL	751	O60437
EDMAVDQSIVSPYTS	KAT14	581	Q9H8E8
EEADVDMEPNVSVYS	INTS2	361	Q9H0H0
MEEDDSYVPSDLTAE	CYTH1	1	Q15438
SDDSSEEDPYMNDTV	MYO10	1026	Q9HD67
YLEMAAGSEPESVEA	KMT2E	16	Q8IZD2
SIDSNPYDTDKMAAE	NSF	106	P46459
NPSELDELMSEEAYE	GCSH	151	P23434
YVIENEMADSPEFTS	KCNG1	396	Q9UIX4
PEDMGATAVYELDTE	RNF113A	111	O15541
SPRQTMDYDDEETDS	KDM5A	1331	P29375
EMYQPEDDNNSDVTS	PEG3	126	Q9GZU2
PAMVDDESDYQTEYE	PNPLA7	1251	Q6ZV29
YNPSDSGPEMEETES	PACS1	376	Q6VY07
TSEPAKEEDDYDVMQ	PIPSL	801	A2A3N6
MPEYDTDTPLNETDT	PTPRT	591	O14522
MSSSYDEASLAPEET	PACSIN1	1	Q9BY11
EPQYEPANTSEDLDM	ATRX	501	P46100
DEHSDSEMYVMPAEE	BLNK	76	Q8WV28
SEMYVMPAEENADDS	BLNK	81	Q8WV28
ADREMPDSDSEAVYE	CACNA1G	681	O43497
ESSETPDQFMTADET	CD44	716	P16070
VNSETGYTPEDTMDS	DCST1	201	Q5T197
EEVQAIMEAYESDPT	CDO1	31	Q16878
PSESEIYEAGAEDRM	AGAP7P	26	Q5VUJ5
APEMLSDGEYISDVE	ANK3	856	Q12955
TFPEEMGETQSEYSD	BCL6	496	P41182
NAMTNEENPEESEYS	BMP5	86	P22003
MDLNDTFPEYKETTE	GDA	171	Q9Y2T3
SADSMSIYDDIDADV	ATP5F1C	211	P36542
YSSMPSSTWEDEVEE	CTXN2	56	P0C2S0
QCEGEEDTEYMTPSS	CBL	691	P22681
NDNAPEFAMDYETTV	CDH7	476	Q9ULB5
TMETSNAYVADETPV	FLRT1	481	Q9NZU1
DADVQTMSPEASEYE	CSTF1	86	Q05048
PDLSSMTEEEQIAYA	PSMD4	276	P55036
TSEPAKEEDDYDVMQ	PSMD4	316	P55036
MDPAEEDTNVYTEKH	SDC2	121	P34741
SEMTEQPDYDLETFV	KIF2C	666	Q99661
TYTEEDPEGAMSVVS	CTNND1	111	O60716
EHTSEFYSMDENQPV	MYBL1	316	P10243
SMEDYDEDLVQEASS	FAM153B	56	P0C7A2
MDTNGYETDNLTTDP	MIER1	441	Q8N108
TALTENDDSDEYEEM	RPGR	536	Q92834
MVATVSPAADNYDET	KIF13B	326	Q9NQT8
VDYMSDGSSSSQEEP	GTF2F1	271	P35269
EMEKSSFTEYIESPD	TAF7L	246	Q5H9L4
EKASMDVENPDYSEE	UTP6	201	Q9NYH9
PSTVTEVDMDLDSYQ	UTRN	301	P46939
QTYEEVGDDALEDPM	TRNAU1AP	231	Q9NX07
ANPTDDTFMVEDAVE	SVOP	61	Q8N4V2
PDESFDEMDSTLAVQ	MOB4	26	Q9Y3A3
MSLVAYASSDESEPD	PRCC	1	Q92733
DDSLYDDKSQAPTMV	PWWP3B	161	Q5H9M0
EENSMSSNIDYDPRE	SAMD9L	111	Q8IVG5
TRMLEDSESSYEPDE	NEO1	1426	Q92859
DSESSYEPDELTKEM	NEO1	1431	Q92859
MAEDLSAATSYTEDD	RNF138	1	Q8WVD3
EPYPDNTDDTADIQM	SETD6	301	Q8TBK2
DSVDSEYDMGSVQRD	SIK2	511	Q9H0K1
FSSDEEVQDNTPSEM	NAP1L3	171	Q99457
SDNENDGYVPDVEMS	JADE1	796	Q6IE81
DGYVPDVEMSDSESE	JADE1	801	Q6IE81
IDAPDDVFYMATEET	MTA1	651	Q13330
TDEEAEGPYSDNEML	REEP3	201	Q6NUK4
DFADEDSAEQLSSPM	SHANK2	1131	Q9UPX8
ADDPSSYMEVVQAAN	CLTC	1131	Q00610
DDDSEYNVDSYSMPV	CLVS2	271	Q5SYC1
DYDMPLDEDEDVTNS	PROKR1	41	Q8TCW9
DHMVPDTESYDAVEI	XIRP2	3106	A4UGR9
LEDYEGESDQETMAP	RIN2	461	Q8WYP3
YGQEVESMETPESKD	ZBTB14	216	O43829
MEFVSSESVTPEDND	SETDB2	506	Q96T68
TDSASPQTYEVELEM	TICRR	1551	Q7Z2Z1
QMVTEDEYEVSSDPE	ZFR2	701	Q9UPR6
DEDAIDPDLMAYLSS	ZBTB7B	306	O15156
PSEMEDVTYSEEDVA	WWC2	681	Q6AWC2
PEDSEYEAEMSLQGE	USP16	476	Q9Y5T5
MPDTEESRLYGDDAT	TIAM1	126	Q13009
EETDMYPEFRQSDEE	IGSF9B	881	Q9UPX0
GDYTPMEDSEETSQS	TPR	1901	P12270
YQMASTSDELDPADQ	SLC7A1	441	P30825
DMSASAGYEEISDPD	SH3PXD2B	501	A1X283
PEAEELSFEVSYSEM	ARHGAP28	281	Q9P2N2
MTADRDPVYDESTDE	XRCC4	221	Q13426
SSMEDADANVYEVEE	FGD6	781	Q6ZV73
VVDESDYMSFINNPS	SCN2A	1086	Q99250
MASESDTEEFYDAPE	WDR44	1	Q5JSH3
QDDPSSSDDEGMPYT	WDR44	466	Q5JSH3
ASDQSMTYESQGPDE	ZDBF2	1631	Q9HCK1
EAMDDYTSAIEVQPN	TTC32	76	Q5I0X7
MEYQSDNPEIDSSFI	ZNF469	851	Q96JG9
MYQPEDDNNSDVTSD	ZIM2	1	Q9NZV7
EETENASEPLGYESM	TOPAZ1	426	Q8N9V7
PDSTEYENFMTETPE	ZGRF1	966	Q86YA3
SESQEMDPVAFDDVA	ZNF69	16	Q9UC07
AVDSTDFNPDDTMSV	TRMT9B	381	Q9P272
NLEVPTYEFTSDDMV	UQCRFS1P1	266	P0C7P4
SSYMSSDNESDIEDE	WNK1	2056	Q9H4A3
RTNPEYENEVEASMD	VIRMA	596	Q69YN4
DNYEEVAMDTDSETS	ZFC3H1	526	O60293
PVSTQMKSCDDEDDY	TEX9	71	Q8N6V9
SMPEVNVDYNASSET	VTCN1	151	Q7Z7D3
VDSEDMYADLASPVS	ZC3H18	726	Q86VM9
VQPSMPTDDYSEESD	ZFHX3	3651	Q15911
SAAEASSEEVPDFME	UNQ6126/PRO20091	61	Q6UXV3
PESLEDVAMYISQEE	ZNF263	216	O14978
FDIITDNPDMNTEDY	PRKCZ	451	Q05513
NEDVDPMAASAEYEL	PPP1R9B	471	Q96SB3