Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

4.90e-07227276GO:0051015
GeneOntologyMolecularFunctionactin binding

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

3.56e-05479276GO:0003779
GeneOntologyMolecularFunctionL-leucine binding

SESN3 SESN1

3.68e-057272GO:0070728
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

ACTN4 ACTN1 ACTN2

7.53e-0561273GO:0030374
GeneOntologyMolecularFunctiontransmembrane transporter binding

ACTN4 ACTN1 ACTN2 ACTN3

7.99e-05172274GO:0044325
GeneOntologyMolecularFunctionintegrin binding

ACTN4 ACTN1 ACTN2 ACTN3

8.55e-05175274GO:0005178
GeneOntologyMolecularFunctionamino acid binding

GLRA3 SESN3 SESN1

1.29e-0473273GO:0016597
GeneOntologyMolecularFunctionvinculin binding

CTNNA1 ACTN1

1.36e-0413272GO:0017166
GeneOntologyMolecularFunctioncytoskeletal protein binding

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

5.04e-041099277GO:0008092
GeneOntologyMolecularFunctioncell adhesion molecule binding

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

1.12e-03599275GO:0050839
GeneOntologyMolecularFunctionstructural constituent of muscle

ACTN2 ACTN3

1.54e-0343272GO:0008307
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

ZFYVE28 ACTN2 SVIL

2.39e-03199273GO:1901981
GeneOntologyMolecularFunctioncalcium ion binding

ACTN4 ACTN1 ACTN2 ACTN3 EDEM1

2.98e-03749275GO:0005509
GeneOntologyMolecularFunctionoxidoreductase activity, acting on peroxide as acceptor

SESN3 SESN1

3.69e-0367272GO:0016684
GeneOntologyMolecularFunctioncarboxylic acid binding

GLRA3 SESN3 SESN1

4.01e-03239273GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

GLRA3 SESN3 SESN1

4.75e-03254273GO:0043177
GeneOntologyMolecularFunctionstructural molecule activity

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

6.23e-03891275GO:0005198
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate binding

ACTN2 SVIL

7.28e-0395272GO:0005546
GeneOntologyMolecularFunctiontranscription coactivator activity

ACTN4 ACTN1 ACTN2

7.73e-03303273GO:0003713
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

FUCA1 EDEM1

8.50e-03103272GO:0004553
GeneOntologyMolecularFunctionphosphatidylinositol binding

ZFYVE28 ACTN2 SVIL

8.67e-03316273GO:0035091
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F22 CYP4B1

1.05e-02115272GO:0004497
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate binding

ACTN2 SVIL

1.16e-02121272GO:1902936
GeneOntologyBiologicalProcesspositive regulation of intracellular transport

PTPN22 ACTN2 EDEM1 RIOK2

7.47e-05162294GO:0032388
GeneOntologyBiologicalProcesscellular response to leucine starvation

SESN3 SESN1

1.25e-0412292GO:1990253
GeneOntologyBiologicalProcesscellular response to L-leucine

SESN3 SESN1

1.47e-0413292GO:0071233
GeneOntologyBiologicalProcessregulation of response to reactive oxygen species

SESN3 SESN1

1.47e-0413292GO:1901031
GeneOntologyBiologicalProcessresponse to L-leucine

SESN3 SESN1

2.26e-0416292GO:0043201
GeneOntologyCellularComponentpseudopodium

ACTN4 ACTN1 ACTN2 ACTN3

9.02e-0918294GO:0031143
GeneOntologyCellularComponentcortical actin cytoskeleton

ACTN4 ACTN1 ACTN2 ACTN3

8.01e-0693294GO:0030864
GeneOntologyCellularComponentactin cytoskeleton

DAPK1 ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

1.07e-05576297GO:0015629
GeneOntologyCellularComponentfocal adhesion

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

2.36e-05431296GO:0005925
GeneOntologyCellularComponentcell-substrate junction

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

2.75e-05443296GO:0030055
GeneOntologyCellularComponentcortical cytoskeleton

ACTN4 ACTN1 ACTN2 ACTN3

2.92e-05129294GO:0030863
GeneOntologyCellularComponentmyofibril

ACTN4 ACTN1 ACTN2 ACTN3 SVIL

3.36e-05273295GO:0030016
GeneOntologyCellularComponentmicrotubule minus-end

CAMSAP2 SVIL

3.89e-057292GO:0036449
GeneOntologyCellularComponentcontractile muscle fiber

ACTN4 ACTN1 ACTN2 ACTN3 SVIL

4.49e-05290295GO:0043292
GeneOntologyCellularComponentZ disc

ACTN4 ACTN1 ACTN2 ACTN3

5.40e-05151294GO:0030018
GeneOntologyCellularComponentI band

ACTN4 ACTN1 ACTN2 ACTN3

7.80e-05166294GO:0031674
GeneOntologyCellularComponentplatelet alpha granule lumen

ACTN4 ACTN1 ACTN2

1.08e-0467293GO:0031093
GeneOntologyCellularComponentGATOR2 complex

SESN3 SESN1

1.22e-0412292GO:0061700
GeneOntologyCellularComponentSeh1-associated complex

SESN3 SESN1

2.20e-0416292GO:0035859
GeneOntologyCellularComponentplatelet alpha granule

ACTN4 ACTN1 ACTN2

2.86e-0493293GO:0031091
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

ACTN4 ACTN2

3.13e-0419292GO:0098871
GeneOntologyCellularComponentsarcomere

ACTN4 ACTN1 ACTN2 ACTN3

3.69e-04249294GO:0030017
GeneOntologyCellularComponentpostsynaptic cytoskeleton

ACTN4 ACTN2

5.92e-0426292GO:0099571
GeneOntologyCellularComponentstriated muscle thin filament

ACTN2 ACTN3

6.38e-0427292GO:0005865
GeneOntologyCellularComponentmyofilament

ACTN2 ACTN3

8.98e-0432292GO:0036379
GeneOntologyCellularComponentsecretory granule lumen

ACTN4 FUCA1 ACTN1 ACTN2

1.00e-03325294GO:0034774
GeneOntologyCellularComponentcytoplasmic vesicle lumen

ACTN4 FUCA1 ACTN1 ACTN2

1.06e-03330294GO:0060205
GeneOntologyCellularComponentactin filament

ACTN1 ACTN2 ACTN3

1.07e-03146293GO:0005884
GeneOntologyCellularComponentvesicle lumen

ACTN4 FUCA1 ACTN1 ACTN2

1.08e-03332294GO:0031983
GeneOntologyCellularComponentmicrotubule end

CAMSAP2 SVIL

1.27e-0338292GO:1990752
GeneOntologyCellularComponentcell cortex

ACTN4 ACTN1 ACTN2 ACTN3

1.63e-03371294GO:0005938
GeneOntologyCellularComponentanchoring junction

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

1.92e-03976296GO:0070161
GeneOntologyCellularComponentintercalated disc

CTNNA1 ACTN1

4.00e-0368292GO:0014704
GeneOntologyCellularComponentsupramolecular fiber

ACTN4 ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

4.93e-031179296GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

ACTN4 ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

5.09e-031187296GO:0099081
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

7.31e-03899295GO:0099513
GeneOntologyCellularComponentcell-cell contact zone

CTNNA1 ACTN1

7.51e-0394292GO:0044291
GeneOntologyCellularComponentcontractile actin filament bundle

ACTN4 ACTN1

9.63e-03107292GO:0097517
GeneOntologyCellularComponentstress fiber

ACTN4 ACTN1

9.63e-03107292GO:0001725
GeneOntologyCellularComponentactomyosin

ACTN4 ACTN1

1.14e-02117292GO:0042641
GeneOntologyCellularComponentactin filament bundle

ACTN4 ACTN1

1.16e-02118292GO:0032432
GeneOntologyCellularComponentsecretory granule

ACTN4 FUCA1 CTNNA1 ACTN1 ACTN2

1.20e-021014295GO:0030141
GeneOntologyCellularComponentpostsynapse

GLRA3 DAPK1 ACTN4 ACTN1 ACTN2

1.22e-021018295GO:0098794
DomainEF-hand_Ca_insen

ACTN4 ACTN1 ACTN2 ACTN3

7.01e-116294IPR014837
DomainEFhand_Ca_insen

ACTN4 ACTN1 ACTN2 ACTN3

7.01e-116294PF08726
DomainActinin_actin-bd_CS

ACTN4 ACTN1 ACTN2 ACTN3

4.07e-0823294IPR001589
DomainACTININ_2

ACTN4 ACTN1 ACTN2 ACTN3

4.07e-0823294PS00020
DomainACTININ_1

ACTN4 ACTN1 ACTN2 ACTN3

4.07e-0823294PS00019
DomainSpectrin

ACTN4 ACTN1 ACTN2 ACTN3

4.07e-0823294PF00435
Domain-

ACTN4 ACTN1 ACTN2 ACTN3 CAMSAP2

7.61e-08712951.10.418.10
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3 CAMSAP2

8.76e-0873295PS50021
DomainCH-domain

ACTN4 ACTN1 ACTN2 ACTN3 CAMSAP2

1.00e-0775295IPR001715
DomainSpectrin_repeat

ACTN4 ACTN1 ACTN2 ACTN3

1.08e-0729294IPR002017
DomainSpectrin/alpha-actinin

ACTN4 ACTN1 ACTN2 ACTN3

1.64e-0732294IPR018159
DomainSPEC

ACTN4 ACTN1 ACTN2 ACTN3

1.64e-0732294SM00150
DomainDUF3657

FAM135A FAM135B

2.33e-062292PF12394
DomainDUF3657

FAM135A FAM135B

2.33e-062292IPR022122
DomainDUF676_lipase-like

FAM135A FAM135B

2.33e-062292IPR007751
DomainDUF676

FAM135A FAM135B

2.33e-062292PF05057
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3

2.97e-0665294SM00033
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3

4.00e-0670294PF00307
DomainPA26

SESN3 SESN1

6.98e-063292PF04636
DomainSestrin

SESN3 SESN1

6.98e-063292IPR006730
DomainAhpD-like

SESN3 SESN1

6.98e-063292IPR029032
Domain-

SESN3 SESN1

6.98e-0632921.20.1290.10
DomainEF-hand_1

ACTN4 ACTN1 ACTN2 ACTN3

8.55e-05152294PF00036
DomainEFh

ACTN4 ACTN1 ACTN2 ACTN3

9.93e-05158294SM00054
DomainEF_HAND_2

ACTN4 ACTN1 ACTN2 ACTN3

4.25e-04231294PS50222
DomainEF_hand_dom

ACTN4 ACTN1 ACTN2 ACTN3

4.32e-04232294IPR002048
Domain-

ACTN4 ACTN1 ACTN2 ACTN3

6.72e-042612941.10.238.10
DomainEF-hand-dom_pair

ACTN4 ACTN1 ACTN2 ACTN3

9.58e-04287294IPR011992
DomainCyt_P450_E_grp-I

CYP4F22 CYP4B1

2.21e-0345292IPR002401
DomainCyt_P450_CS

CYP4F22 CYP4B1

3.05e-0353292IPR017972
DomainCYTOCHROME_P450

CYP4F22 CYP4B1

3.52e-0357292PS00086
Domain-

CYP4F22 CYP4B1

3.65e-03582921.10.630.10
Domainp450

CYP4F22 CYP4B1

3.65e-0358292PF00067
DomainCyt_P450

CYP4F22 CYP4B1

3.90e-0360292IPR001128
Domain-

FAM135A FAM135B

1.46e-021192923.40.50.1820
DomainAB_hydrolase

FAM135A FAM135B

1.46e-02119292IPR029058
PathwayBIOCARTA_CELL2CELL_PATHWAY

CTNNA1 ACTN1 ACTN2 ACTN3

3.17e-0912244M12851
PathwayREACTOME_NEPHRIN_FAMILY_INTERACTIONS

ACTN4 ACTN1 ACTN2 ACTN3

5.60e-0823244M913
PathwayKEGG_ADHERENS_JUNCTION

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

1.28e-0773245M638
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

1.37e-0774245M39462
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

1.37e-0774245M16376
PathwayBIOCARTA_CELL2CELL_PATHWAY

CTNNA1 ACTN2 ACTN3

3.62e-079243MM1366
PathwayKEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

1.30e-06116245M2164
PathwayBIOCARTA_UCALPAIN_PATHWAY

ACTN1 ACTN2 ACTN3

1.56e-0614243M13143
PathwayKEGG_TIGHT_JUNCTION

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

2.46e-06132245M11355
PathwayREACTOME_CELL_CELL_COMMUNICATION

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

5.41e-06155245M522
PathwayBIOCARTA_INTEGRIN_PATHWAY

ACTN1 ACTN2 ACTN3

2.51e-0534243M3342
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

ACTN4 ACTN2 ACTN3

3.52e-0538243M39549
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

ACTN4 ACTN1 ACTN2 ACTN3

8.25e-05139244M4741
PathwayBIOCARTA_UCALPAIN_PATHWAY

ACTN2 ACTN3

1.81e-0412242MM1525
PathwayREACTOME_EICOSANOIDS

CYP4F22 CYP4B1

1.81e-0412242MM14845
PathwayREACTOME_EICOSANOIDS

CYP4F22 CYP4B1

1.81e-0412242M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F22 CYP4B1

1.81e-0412242M27128
PathwayREACTOME_FATTY_ACIDS

CYP4F22 CYP4B1

2.88e-0415242M27126
PathwayKEGG_FOCAL_ADHESION

ACTN4 ACTN1 ACTN2 ACTN3

3.28e-04199244M7253
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F22 CYP4B1

4.18e-0418242MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F22 CYP4B1

4.18e-0418242MM14841
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

ACTN4 ACTN1 ACTN2 ACTN3

4.25e-04213244M18306
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F22 CYP4B1

5.72e-0421242M27137
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F22 CYP4B1

8.14e-0425242MM14858
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY

ACTN4 ACTN1

1.17e-0330242M47724
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

ACTN4 ACTN1 ACTN2

1.35e-03130243MM15455
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

ACTN4 ACTN1 ACTN2

1.41e-03132243M724
PathwayBIOCARTA_INTEGRIN_PATHWAY

ACTN2 ACTN3

1.42e-0333242MM1426
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

ACTN2 ACTN3

1.60e-0335242MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

ACTN2 ACTN3

1.69e-0336242M18647
PathwayPID_ECADHERIN_STABILIZATION_PATHWAY

CTNNA1 ACTN1

2.19e-0341242M232
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F22 CYP4B1

2.40e-0343242MM15873
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F22 CYP4B1

4.48e-0359242M27140
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F22 CYP4B1

4.78e-0361242MM14861
PathwayPID_AR_PATHWAY

ZNF318 SVIL

4.78e-0361242M58
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F22 CYP4B1

4.94e-0362242M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F22 CYP4B1

5.25e-0364242M5650
PathwayWP_P53_SIGNALING

SESN3 SESN1

5.41e-0365242MM15852
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F22 CYP4B1

5.58e-0366242MM14839
PathwayKEGG_P53_SIGNALING_PATHWAY

SESN3 SESN1

5.91e-0368242M6370
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

SESN3 SESN1

6.78e-0373242MM15223
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

CTNNA1 ACTN1

6.78e-0373242MM15126
Pubmed

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

ACTN4 ACTN1 ACTN2 ACTN3

3.90e-13429416807302
Pubmed

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.

ACTN4 ACTN1 ACTN2 ACTN3

3.90e-1342941629252
Pubmed

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.

ACTN4 ACTN1 ACTN2 ACTN3

1.95e-12529412837758
Pubmed

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.

ACTN4 ACTN1 ACTN2 ACTN3

1.95e-12529419943616
Pubmed

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

ACTN4 ACTN1 ACTN2 ACTN3

1.95e-12529415841212
Pubmed

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

ACTN4 ACTN1 ACTN2 ACTN3

5.84e-12629418425115
Pubmed

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.

ACTN4 ACTN1 ACTN2 ACTN3

5.84e-12629422693585
Pubmed

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.

ACTN4 ACTN1 ACTN2 ACTN3

2.72e-11829420215401
Pubmed

Mice deficient in alpha-actinin-4 have severe glomerular disease.

ACTN4 ACTN1 ACTN2 ACTN3

2.72e-11829412782671
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

ACTN4 ACTN1 ACTN2 ACTN3

8.15e-111029420368620
Pubmed

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.

ACTN4 ACTN1 ACTN2 ACTN3

1.92e-101229415465019
Pubmed

α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.

ACTN4 ACTN1 ACTN3

5.21e-10329321784188
Pubmed

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.

ACTN4 ACTN2 ACTN3

5.21e-1032938104223
Pubmed

The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.

ACTN4 ACTN2 ACTN3

5.21e-10329310656685
Pubmed

Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

ACTN4 ACTN1 ACTN2 ACTN3

5.29e-101529411440986
Pubmed

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.

ACTN4 ACTN1 ACTN2 ACTN3

6.75e-092729436899856
Pubmed

Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.

ACTN4 ACTN1 ACTN2

1.82e-08729311724819
Pubmed

Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

ACTN1 ACTN2 ACTN3

4.36e-08929311114196
Pubmed

α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.

ACTN4 ACTN1

6.71e-07229223454549
Pubmed

Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3).

ZIM2 PEG3

6.71e-07229210708526
Pubmed

α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms.

ACTN2 ACTN3

6.71e-07229222253474
Pubmed

alpha-actinin-3 and performance.

ACTN2 ACTN3

6.71e-07229219696509
Pubmed

Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin.

CTNNA1 ACTN1

6.71e-0722927790378
Pubmed

Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.

ACTN4 ACTN1

6.71e-07229234010028
Pubmed

Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo.

ACTN2 ACTN3

6.71e-0722929675099
Pubmed

Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.

ACTN4 ACTN1

6.71e-07229220156433
Pubmed

An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.

ACTN4 ACTN1

6.71e-07229223557398
Pubmed

Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.

ACTN1 ACTN2

6.71e-07229223664615
Pubmed

Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.

ACTN2 ACTN3

6.71e-07229232451822
Pubmed

Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11.

ACTN2 ACTN3

6.71e-0722921339456
Pubmed

Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.

ACTN2 ACTN3

6.71e-07229219150855
Pubmed

Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.

ACTN4 ACTN1

6.71e-07229220037648
Pubmed

Sestrins induce natural killer function in senescent-like CD8+ T cells.

SESN3 SESN1

6.71e-07229232231301
Pubmed

HAMLET binding to α-actinin facilitates tumor cell detachment.

ACTN4 ACTN1

6.71e-07229221408150
Pubmed

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.

ACTN4 ACTN1

6.71e-07229228797528
Pubmed

Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.

ACTN4 ACTN1 SVIL

6.86e-072129312202484
Pubmed

Colocalization of α-actinin and synaptopodin in the pyramidal cell axon initial segment.

ACTN4 ACTN2

2.01e-06329221940706
Pubmed

Direct binding of alpha-actinin enhances TRPP3 channel activity.

ACTN1 ACTN2

2.01e-06329217944866
Pubmed

Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes.

ACTN1 ACTN2

2.01e-06329230768638
Pubmed

Sestrins are evolutionarily conserved mediators of exercise benefits.

SESN3 SESN1

2.01e-06329231929512
Pubmed

Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.

ACTN4 ACTN1

2.01e-06329216751418
Pubmed

The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism.

ACTN1 ACTN2

2.01e-06329211101506
Pubmed

Sestrin1, 2, and 3 are dispensable for female fertility in mice.

SESN3 SESN1

2.01e-06329238297375
Pubmed

Circulating Sestrin Levels Are Increased in Hypertension Patients.

SESN3 SESN1

2.01e-06329232626541
Pubmed

Interaction of PKN with alpha-actinin.

ACTN1 ACTN2

2.01e-0632929030526
Pubmed

Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis.

SESN3 SESN1

2.01e-06329231073887
Pubmed

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.

ACTN4 ACTN1

2.01e-06329223890175
Pubmed

PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse.

SESN3 SESN1

2.01e-06329212607115
Pubmed

Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.

ACTN4 ACTN1

2.01e-06329216951376
Pubmed

The functions and roles of sestrins in regulating human diseases.

SESN3 SESN1

2.01e-06329234979914
Pubmed

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.

ACTN4 ACTN1 ACTN2

2.31e-063129314630798
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

ACTN4 CTNNA1 ACTN1 SVIL

2.80e-0611829427377895
Pubmed

Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.

ACTN4 ACTN1

4.02e-06429222351778
Pubmed

CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.

ACTN4 ACTN1

4.02e-06429210753915
Pubmed

Titin mutations as the molecular basis for dilated cardiomyopathy.

ACTN1 ACTN2

4.02e-06429211846417
Pubmed

ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.

ACTN1 ACTN2

4.02e-06429212446711
Pubmed

Interactions of a hemidesmosome component and actinin family members.

ACTN4 ACTN1

4.02e-06429211739652
Pubmed

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

SESN3 SESN1

4.02e-06429222958918
Pubmed

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.

ACTN4 ACTN1

4.02e-06429223515331
Pubmed

Molecular structure of the sarcomeric Z-disk: two types of titin interactions lead to an asymmetrical sorting of alpha-actinin.

ACTN1 ACTN2

4.02e-0642929501083
Pubmed

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

ACTN4 ACTN1

4.02e-0642922116421
Pubmed

Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptors.

ACTN4 ACTN2

4.02e-06429216510730
Pubmed

Structural dynamics of alpha-actinin-vinculin interactions.

ACTN4 ACTN1

4.02e-06429215988023
Pubmed

Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines.

ACTN2 ACTN3

6.70e-06529211171996
Pubmed

Different MRF4 knockout alleles differentially disrupt Myf-5 expression: cis-regulatory interactions at the MRF4/Myf-5 locus.

ACTN2 ACTN3

6.70e-0652929268580
Pubmed

Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.

ACTN1 ACTN2

6.70e-06529215665106
Pubmed

The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.

ACTN4 ACTN1

6.70e-06529216501493
Pubmed

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling.

ACTN2 ACTN3

6.70e-06529221536590
Pubmed

p27Kip1 is expressed transiently in developing myotomes and enhances myogenesis.

ACTN2 ACTN3

6.70e-0652929438383
Pubmed

Sestrin2 is a leucine sensor for the mTORC1 pathway.

SESN3 SESN1

6.70e-06529226449471
Pubmed

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.

ACTN4 ACTN1 ACTN3

7.22e-064529322114352
Pubmed

The protein-tyrosine phosphatase SHP-1 regulates the phosphorylation of alpha-actinin.

ACTN4 ACTN1

1.00e-05629215070900
Pubmed

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

SESN3 SESN1

1.41e-05729225259925
Pubmed

Temporal and spatial expression pattern of beta1 sodium channel subunit during heart development.

ACTN1 ACTN2

1.41e-05729215721864
Pubmed

An Unbiased Proteomics Method to Assess the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.

ACTN1 ACTN2

1.41e-05729231573406
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DAPK1 ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

1.59e-05143129837142655
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

ACTN2 ACTN3

1.87e-05829211309420
Pubmed

The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner.

ACTN2 ACTN3

1.87e-05829211381084
Pubmed

The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.

ACTN2 ACTN3

1.87e-05829218687124
Pubmed

DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.

ACTN4 ACTN1 SVIL

2.00e-056329337052853
Pubmed

Proteomic and functional evidence for a P2X7 receptor signalling complex.

ACTN4 SVIL

3.68e-051129211707406
Pubmed

Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

ACTN1 ACTN2

3.68e-051129211842093
Pubmed

Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium.

ACTN2 ACTN3

3.68e-051129216585392
Pubmed

Luzp4 defines a new mRNA export pathway in cancer cells.

ACTN4 ACTN1 SVIL

4.10e-058029325662211
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

ACTN4 CTNNA1 ACTN1 SVIL

4.23e-0523529428378594
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

ACTN2 ACTN3

4.41e-05122928618961
Pubmed

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).

CTNNA1 ACTN1

4.41e-051229216973135
Pubmed

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

SESN3 SESN1

4.41e-051229225263562
Pubmed

Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.

ACTN4 ACTN1

5.21e-051329228079882
Pubmed

Mechanical regulation of glycolysis via cytoskeleton architecture.

ACTN4 ACTN1

6.07e-051429232051585
Pubmed

Selection system for genes encoding nuclear-targeted proteins.

NOL4 ZNF318

6.07e-05142929853615
Pubmed

Filamin C is Essential for mammalian myocardial integrity.

ACTN4 ACTN2

6.07e-051429236706168
Pubmed

Genome-wide association study of chronic periodontitis in a general German population.

ACTN1 ACTN2 FAM135B

7.07e-059629324024966
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

ACTN4 CTNNA1 ACTN1 SVIL

7.66e-0527429434244482
Pubmed

Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.

ACTN4 ACTN1

8.00e-051629235390516
Pubmed

Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.

ACTN4 ACTN1

8.00e-051629216944923
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

ACTN4 CTNNA1 ACTN1 SVIL

8.92e-0528529421423176
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

ACTN1 ACTN2

1.02e-041829224840128
Pubmed

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.

ACTN4 ACTN1 ACTN2

1.09e-0411129321163940
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

ACTN4 ACTN1 ACTN2

1.30e-0411829321078624
InteractionMYOZ2 interactions

ACTN4 ACTN1 ACTN2 ACTN3

2.48e-0822294int:MYOZ2
InteractionADORA2A interactions

ACTN4 ACTN1 ACTN2 ACTN3

5.93e-0827294int:ADORA2A
InteractionACTN1 interactions

DAPK1 ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 SVIL

4.23e-07341297int:ACTN1
InteractionSYNPO2L interactions

ACTN1 ACTN2 ACTN3

4.39e-0711293int:SYNPO2L
InteractionMYOZ1 interactions

ACTN4 ACTN1 ACTN2 ACTN3

5.91e-0747294int:MYOZ1
InteractionMYH2 interactions

ACTN4 ACTN1 ACTN2 SVIL

9.64e-0753294int:MYH2
InteractionNKAPD1 interactions

ACTN1 ACTN2 ACTN3 C9orf78 GPATCH1

3.11e-06161295int:NKAPD1
InteractionMYH15 interactions

ACTN4 ACTN1 ACTN3

3.50e-0621293int:MYH15
InteractionMYOT interactions

ACTN1 ACTN2 ACTN3

3.50e-0621293int:MYOT
InteractionPDLIM1 interactions

ACTN4 ACTN1 ACTN2 ACTN3

1.05e-0596294int:PDLIM1
InteractionACTN3 interactions

ACTN4 ACTN1 ACTN2 ACTN3

1.73e-05109294int:ACTN3
InteractionACTN4 interactions

DAPK1 ACTN4 ACTN1 ACTN2 ACTN3 SVIL

1.90e-05400296int:ACTN4
InteractionDUX1 interactions

ACTN2 ACTN3

4.18e-057292int:DUX1
InteractionMICALL2 interactions

ACTN4 ACTN1 ACTN2 ACTN3

4.76e-05141294int:MICALL2
InteractionSSX2IP interactions

PTPN22 ACTN1 ACTN2 CAMSAP2 GPATCH1

5.16e-05288295int:SSX2IP
InteractionVASP interactions

ACTN4 ACTN1 CAMSAP2 FAM135A SVIL

5.69e-05294295int:VASP
InteractionCIMAP1B interactions

ACTN2 ACTN3

8.93e-0510292int:CIMAP1B
InteractionZYX interactions

ACTN4 CTNNA1 ACTN1 FAM135A SVIL

9.68e-05329295int:ZYX
InteractionACTN2 interactions

ACTN4 ACTN1 ACTN2 ACTN3

1.01e-04171294int:ACTN2
InteractionRRAGA interactions

ACTN1 EDEM1 NOL8

1.10e-0465293int:RRAGA
InteractionMYH7B interactions

ACTN4 ACTN1 ACTN2

1.15e-0466293int:MYH7B
InteractionTSC1 interactions

DAPK1 ACTN1 ACTN2 EDEM1 GPATCH1

1.59e-04366295int:TSC1
InteractionRAVER1 interactions

ACTN4 ACTN1 ACTN2 C9orf78

1.64e-04194294int:RAVER1
InteractionNEBL interactions

CTNNA1 ACTN1 ACTN3

1.97e-0479293int:NEBL
InteractionDDIAS interactions

ACTN4 ACTN1

2.08e-0415292int:DDIAS
InteractionDAPK1 interactions

DAPK1 ACTN4 ACTN1 SVIL

2.18e-04209294int:DAPK1
InteractionMYO1C interactions

DAPK1 ACTN4 RIOK2 C9orf78 SVIL

2.33e-04397295int:MYO1C
InteractionDBN1 interactions

DAPK1 ACTN4 ACTN1 RIOK2 SVIL

2.92e-04417295int:DBN1
InteractionSVIL interactions

DAPK1 ACTN4 ACTN1 SVIL

3.30e-04233294int:SVIL
InteractionLIMA1 interactions

DAPK1 ACTN4 CAMSAP2 C9orf78 SVIL

3.33e-04429295int:LIMA1
InteractionZNF383 interactions

ZIM2 NOL4

3.37e-0419292int:ZNF383
InteractionRGS9 interactions

ACTN4 ACTN2

3.37e-0419292int:RGS9
InteractionUSP2 interactions

ZIM2 ACTN1 ACTN2 ACTN3

3.63e-04239294int:USP2
InteractionLIMS1 interactions

ZIM2 DAPK1 PEG3

3.72e-0498293int:LIMS1
InteractionLUZP4 interactions

ACTN4 ACTN1 SVIL

3.83e-0499293int:LUZP4
InteractionPCP2 interactions

CTNNA1 ACTN1

4.13e-0421292int:PCP2
InteractionTRIM33 interactions

ZIM2 ACTN4 CTNNA1 ACTN1 C9orf78

4.27e-04453295int:TRIM33
InteractionCLEC4D interactions

ACTN4 CTNNA1 ACTN1 ACTN2

5.06e-04261294int:CLEC4D
InteractionATXN7 interactions

ACTN4 ACTN1 ACTN2

5.08e-04109293int:ATXN7
InteractionPDLIM7 interactions

ACTN4 CTNNA1 ACTN1 SVIL

5.28e-04264294int:PDLIM7
InteractionSORBS2 interactions

ACTN4 CTNNA1 ACTN1

5.35e-04111293int:SORBS2
InteractionMAP1S interactions

EDEM1 CAMSAP2 C9orf78

5.50e-04112293int:MAP1S
InteractionPTPRQ interactions

CTNNA1 ACTN1

5.88e-0425292int:PTPRQ
InteractionKCTD13 interactions

DAPK1 ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3 CAMSAP2 SVIL

5.93e-041394298int:KCTD13
InteractionARX interactions

ACTN1 ACTN2

7.38e-0428292int:ARX
InteractionMAPRE1 interactions

ACTN4 CTNNA1 ACTN1 CAMSAP2 SVIL

7.57e-04514295int:MAPRE1
InteractionINSIG1 interactions

ACTN4 CTNNA1 ACTN1

7.92e-04127293int:INSIG1
InteractionTTN interactions

ACTN4 ACTN1 ACTN2 ACTN3

8.42e-04299294int:TTN
Cytoband19q13.4

ZIM2 PEG3

1.15e-037929219q13.4
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZIM2 ACTN4 GPATCH1 PEG3

6.40e-031192294chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr9q21

DAPK1 TRPM3

7.03e-03199292chr9q21
GeneFamilyActinins

ACTN4 ACTN1 ACTN2 ACTN3

5.35e-1341741112
GeneFamilyCytochrome P450 family 4

CYP4F22 CYP4B1

5.14e-04361721003
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZIM2 ZNF318 PEG3

2.80e-0271817328
CoexpressionHALLMARK_APICAL_JUNCTION

ACTN4 CTNNA1 ACTN1 ACTN2 ACTN3

2.52e-06200295M5915
CoexpressionMARZEC_IL2_SIGNALING_DN

SESN3 DAPK1 SESN1

8.48e-0636293M13276
CoexpressionGSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP

SESN3 ACTN1 ACTN2 SESN1

3.26e-05166294M7009
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN

PTPN22 SESN1 GPATCH1 NOL8

6.34e-05197294M9916
CoexpressionGSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP

CTNNA1 ACTN1 EDEM1 SVIL

6.60e-05199294M9491
CoexpressionGSE33424_CD161_HIGH_VS_INT_CD8_TCELL_DN

PTPN22 ACTN1 ACTN2 EDEM1

6.73e-05200294M8540
CoexpressionGSE17721_LPS_VS_CPG_6H_BMDC_DN

GLRA3 DAPK1 ACTN4 PEG3

6.73e-05200294M3999
CoexpressionGSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN

DAPK1 FUCA1 ACTN1 CAMSAP2

6.73e-05200294M7453
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP

ZFYVE28 DAPK1 ACTN1 EDEM1

6.73e-05200294M9205
CoexpressionMURARO_PANCREAS_DELTA_CELL

SESN3 NOL4 TMEM200A PEG3

1.59e-04250294M39170
CoexpressionPLASARI_TGFB1_TARGETS_10HR_DN

SESN3 SESN1 SVIL PEG3

1.79e-04258294M2446
ToppCell356C-Lymphocytic-ILC|356C / Donor, Lineage, Cell class and subclass (all cells)

CYP4F22 PTPN22 C9orf78 TMEM200A

4.87e-061752947fa8330ce813c48bd332be618909e5ec8d0f5d7e
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ACTN4 ACTN1 ACTN2 SVIL

6.46e-061882946d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 TRPM3 FAM135A PEG3

7.02e-061922945b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 ACTN1 EDEM1 SESN1

7.02e-06192294cd9bccbef1ef6bb39c310039884e2acb81e63c7c
ToppCellfacs-Skin-Telogen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA1 CYP4B1 SESN1 PEG3

7.32e-06194294ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA1 CYP4B1 SESN1 PEG3

7.32e-061942944d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCellfacs-Skin-Telogen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA1 CYP4B1 SESN1 PEG3

7.32e-06194294bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN1 CYP4B1 SESN1 PEG3

7.62e-0619629490edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCellCOVID-19-Lymphoid-CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

SESN3 SESN1 TMEM200A SVIL

7.62e-0619629428515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN1 CYP4B1 SESN1 PEG3

7.62e-06196294c936014125b2ed5f796221b74acb77b8f8359875
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ACTN3 RIOK2

9.52e-05137293e9b88ad86b75454a8292a94879c5b665adc42744
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 FAM135B SVIL

1.32e-041532933b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLRA3 CYP4B1 PEG3

1.35e-04154293ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GLRA3 TRPM3 FAM135B

1.40e-041562938353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFYVE28 PTPN22 TMEM200A

1.51e-041602938e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZIM2 PTPN22 SESN1

1.53e-04161293d59713ca84aa2acadfc9b3150d5f525e1b288860
ToppCellImmune_cells-T_cells|World / Lineage and Cell class

PTPN22 ACTN1 ACTN2

1.59e-04163293c5afdb5e7700bbd3ee8276910f9c4b4b3bcc3266
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN3 TMEM200A GPATCH1

1.65e-041652931703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCelldroplet-Heart-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAPK1 SESN1 SVIL

1.77e-041692932e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4F22 PTPN22 ACTN2

1.77e-041692933c4c3279cd72f39b5e7ff77741950ed3873c0317
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 TRPM3 CYP4B1

1.77e-041692936937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4F22 PTPN22 ACTN2

1.77e-04169293d6437afa298c280d202ba686338c6d8a37bd7ab7
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 TRPM3 CYP4B1

1.77e-041692930cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ZFYVE28 PTPN22

1.80e-04170293064786c1f1ad7665358964765910b0ad46d14685
ToppCelldroplet-Lung-nan-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ZFYVE28 PTPN22

1.80e-041702936725747df336697708b94999b3ebb40f1721da16
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CYP4F22 ACTN4 TMEM200A

1.83e-04171293bdd30100b74e012eec3090799c22635aa57fa91d
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACTN1 ACTN2 SVIL

1.90e-04173293cb6389536195443633adb06e5f1b7483530773d1
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZFYVE28 PTPN22 ACTN3

1.93e-0417429333d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFYVE28 CYP4F22 TMEM200A

1.96e-041752938269721389a3ce98681460e6393f2cff816eaa25
ToppCellfacs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 EDEM1 FAM135A

2.00e-041762935f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLRA3 TRPM3 TMEM200A

2.00e-0417629340993c41c1017b53039a337174fc56632b278609
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFYVE28 PTPN22 TMEM200A

2.00e-041762936b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN22 ACTN1 ACTN2

2.03e-04177293ac0cf03e2a1baf84db3ae245d59bbc6ae52c13be
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.03e-041772939af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 EDEM1 FAM135A

2.03e-0417729335d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.06e-04178293aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM3 FAM135A PEG3

2.06e-04178293fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellImmune_cells-T_cells|Immune_cells / Lineage and Cell class

PTPN22 ACTN1 ACTN2

2.06e-04178293af420242277e2a4e2524002a2914b0538f79a134
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZIM2 ACTN2 PEG3

2.06e-04178293a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTN2 TMEM200A SVIL

2.06e-04178293a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell356C-Lymphocytic-ILC-ILC-1|356C / Donor, Lineage, Cell class and subclass (all cells)

PTPN22 C9orf78 TMEM200A

2.06e-0417829340df4bb0978e5e5568c52ad4a5881ea0cdc6941d
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPN22 SESN1 TMEM200A

2.10e-04179293d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

ACTN1 ACTN2 SVIL

2.13e-04180293d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SESN3 ZNF318 SESN1

2.17e-04181293477c572c5c1efceee49732cc9e8b1dad68a7e6e5
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.17e-04181293b45b11428d13950369347e051d4d517efb2bd4fd
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-B_cell-B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SESN3 ZNF318 SESN1

2.17e-04181293909280b44085d8e96fcd3cbcba6bff94badd41e8
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ZNF318 SESN1

2.17e-04181293ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4F22 ACTN2 ACTN3

2.20e-04182293edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SESN3 NOL4 DAPK1

2.24e-04183293cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.27e-0418429342ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellT_cells-Resident_memory_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ZFYVE28 PTPN22 TMEM200A

2.27e-04184293e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 EDEM1 SESN1

2.31e-04185293dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFYVE28 PTPN22 TMEM200A

2.31e-04185293f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.31e-041852933937e026add96a396122139daf8011cfbc60e75c
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

DAPK1 FUCA1 ACTN1

2.31e-0418529323ffba9216729b5bdb30b35742ba2627bb1200bf
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 ACTN1 EDEM1

2.31e-041852937acc071ea75442817db4d98bd3ed3fff6f0a9d46
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFYVE28 PTPN22 TMEM200A

2.35e-04186293bbcd9062c0f6f65ca6f3cb101b6fa72ddd1e14fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SESN3 NOL4 DAPK1

2.35e-041862933dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.35e-041862934e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.35e-041862933aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ZNF318 ACTN2

2.38e-0418729391c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK1 TRPM3 CYP4B1

2.38e-0418729358d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 FAM135A SVIL

2.38e-0418729387b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SESN3 ZNF318 ACTN2

2.38e-04187293382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 FAM135A SVIL

2.38e-0418729342a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 FAM135A SVIL

2.38e-0418729364afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17|lymph-node_spleen / Manually curated celltypes from each tissue

ZFYVE28 ACTN2 TMEM200A

2.42e-04188293a20521198c6db17589535fb439533329582c9dd2
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 EDEM1 SESN1

2.42e-0418829359b71462338a7efbacf46577cb07e9db3363afee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SESN3 NOL4 DAPK1

2.46e-041892931ecf9911ff82e0ca0f0c101b735d3b1f3b339d57
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

DAPK1 ACTN1 TRPM3

2.46e-0418929375c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTN4 FAM135A SVIL

2.46e-041892938c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTN4 FAM135A SVIL

2.46e-041892935d902a4660a27548764bf04c6de152b565da835c
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ACTN4 ACTN2 SVIL

2.46e-041892930a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA1 SVIL PEG3

2.50e-041902931d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN4 CTNNA1 CYP4B1

2.50e-041902931ff2295c9fc94ea21fff286706b739d0deb032d0
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN4 CTNNA1 CYP4B1

2.50e-04190293d415c8f3d69a8142e95307aeabc6d0e812cd5165
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ACTN4 ACTN2 SVIL

2.50e-0419029393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 ACTN1 SVIL

2.50e-04190293f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN4 CTNNA1 CYP4B1

2.50e-0419029361f2f9fb4b8f47a2a669f6b052214d2ce0c194cd
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 EDEM1 SESN1

2.50e-041902932f5460fa028dfe6b80dd024063a4513dc532a94d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 ACTN1 SVIL

2.50e-04190293562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FUCA1 TMEM200A SVIL

2.54e-04191293156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYP4F22 PTPN22 TMEM200A

2.54e-0419129395ae42d145adb478d886a2259baacc713cd6587b
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZFYVE28 PTPN22 TMEM200A

2.54e-04191293c7be771543089fc94e5c62fd22f745189642aec3
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 ACTN1 EDEM1

2.54e-041912934bd9db45e7b5c0d04368e08c8199d390744aa317
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

ACTN4 ACTN2 SVIL

2.54e-041912935d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

DAPK1 ACTN1 TRPM3

2.58e-04192293c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZIM2 SVIL PEG3

2.58e-0419229320ede290e01ad574afd122d72b59dbc52c595fad
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP4F22 DAPK1 SVIL

2.58e-041922937bcdbd97fa8c3bfccde426d44979601226913fc3
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FUCA1 ACTN1 SVIL

2.62e-04193293c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FUCA1 SVIL PEG3

2.62e-041932937cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

SESN3 ACTN1 SVIL

2.62e-04193293772e0370bda4bffed7798b8714e32c9e2a1d9b67
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ACTN1 SVIL

2.62e-04193293263d185af6ed80e639f864e4966268e0862c61dc
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZFYVE28 PTPN22 TMEM200A

2.62e-04193293b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 ACTN3 PEG3

2.62e-041932931aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ACTN4 ACTN2 SVIL

2.66e-0419429389812fb164065041357bb37a3c2d87028ec3de4e
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD4+_Th|metastatic_Lymph_Node / Location, Cell class and cell subclass

ZFYVE28 PTPN22 TMEM200A

2.66e-041942931ce9b4c1fbdbc5e39c03adf7ffba3d0efea81862
ToppCellCTRL-Myeloid-Alveolar_Macrophage|CTRL / Disease state, Lineage and Cell class

DAPK1 ACTN1 SVIL

2.66e-04194293be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCellMild-CD8+_T|Mild / Disease group and Cell class

ZFYVE28 PTPN22 TMEM200A

2.66e-04194293c3dba9ff0ab98b6a955b32d071ad7e397dcdc6e9
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ACTN1 TMEM200A SVIL

2.70e-04195293bff7685784688425bebd78b0f284a6d4475a9415
Drugconen

ACTN4 ACTN1 ACTN2

8.37e-0715293CID000093117
Drugprostaglandin A1

ACTN4 ACTN1 ACTN3

1.08e-0534293ctd:C100573
Drugsilicon cation

ZIM2 PEG3

1.56e-055292CID016019983
DrugAC1O1J2W

ZIM2 ACTN4 PEG3

2.38e-0544293CID006122347
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN4 ACTN1 ACTN2 ACTN3

3.24e-125284DOID:0111128 (implicated_via_orthology)
Diseaseimmature platelet measurement

ACTN1 TRPM3 SVIL

1.95e-04119283EFO_0803541
DiseaseAcute Myeloid Leukemia, M1

DAPK1 CTNNA1 SVIL

2.25e-04125283C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

DAPK1 CTNNA1 SVIL

2.25e-04125283C1879321
DiseaseHematopoetic Myelodysplasia

DAPK1 CTNNA1

3.47e-0429282C2713368
DiseaseLeukemia, Myelocytic, Acute

DAPK1 CTNNA1 SVIL

5.83e-04173283C0023467
Diseaseage-related macular degeneration, disease progression measurement

CYP4B1 FAM135B

6.96e-0441282EFO_0001365, EFO_0008336
DiseaseMalignant neoplasm of salivary gland

ZIM2 DAPK1

8.38e-0445282C0220636
DiseaseSalivary Gland Neoplasms

ZIM2 DAPK1

9.14e-0447282C0036095
Diseaseperiodontitis

ACTN1 ACTN2 FAM135B

1.21e-03223283EFO_0000649
DiseaseMYELODYSPLASTIC SYNDROME

DAPK1 CTNNA1

1.85e-0367282C3463824
Diseaseresponse to selective serotonin reuptake inhibitor

ACTN1 TRPM3

2.75e-0382282EFO_0005658
Diseasedescending aortic diameter

ACTN4 SVIL

3.16e-0388282EFO_0021788
Diseaseplatelet measurement

ACTN4 ACTN1 TRPM3

3.24e-03315283EFO_0005036
DiseaseAdenoid Cystic Carcinoma

ZIM2 DAPK1

4.06e-03100282C0010606
Diseasemigraine disorder

ACTN4 TRPM3 SVIL

4.60e-03357283MONDO_0005277
Diseasepeptide measurement

GLRA3 CYP4B1

4.80e-03109282EFO_0010520
Diseaseimmature platelet fraction

ACTN1 TRPM3

5.24e-03114282EFO_0009187

Protein segments in the cluster

PeptideGeneStartEntry
ARSDDTLDEEDSFVM

DAPK1

331

P53355
AFIDFMSRETADTDT

ACTN1

811

P12814
DFMTRETADTDTAEQ

ACTN2

816

P35609
FIDFMSRETTDTDTA

ACTN4

831

O43707
FYRFSDMDDEVRESR

GLRA3

366

O75311
DMDDEVRESRFSFTA

GLRA3

371

O75311
MEIKESSSFDFRTSE

PTPN22

346

Q9Y2R2
RSGSDEEERVFFMDD

ZFYVE28

391

Q9HCC9
DTFADFDSMTDRLLD

FAM135A

1291

Q9P2D6
MAARDSDSEEDLVSY

GPATCH1

1

Q9BRR8
YRRDMALSDVTEESE

FUCA1

306

P04066
DDRFRMDSRFLETDS

NOL8

876

Q76FK4
AKTSFEMDREDDRDS

PEG3

201

Q9GZU2
SDFETEDFDVRSRTS

CTNNA1

641

P35221
STEDRMESFFLSETC

EDEM1

541

Q92611
SDADLRAEVDTFMFE

CYP4B1

301

P13584
SSTLDEEVSERMFSF

FAM135B

1081

Q49AJ0
RDYTVSLDSDMDDAS

CAMSAP2

641

Q08AD1
SDEDIRAEADTFMFE

CYP4F22

321

Q6NT55
RESMFVFSSDDEEVT

SESN1

306

Q9Y6P5
TDEDFEFALDMTRDE

SVIL

2181

O95425
FRSSFRMDSSVEEDE

TMEM200A

216

Q86VY9
SSIESDEFDMSDSTR

NOL4

216

O94818
FIDFMTRETAETDTT

ACTN3

821

Q08043
REDEEASQEEMSTRF

SESN3

276

P58005
FEDITSMDTRSFSSD

TRPM3

1486

Q9HCF6
LSEESADARSFEMTE

RIOK2

381

Q9BVS4
AKTSFEMDREDDRDS

ZIM2

76

Q9NZV7
SFSAETNRRDEDADM

C9orf78

101

Q9NZ63
MDRDDLTDDSVFTRS

ZNF318

181

Q5VUA4