Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionheparan sulfate 6-O-sulfotransferase activity

HS6ST2 HS6ST1 HS6ST3

1.86e-0731153GO:0017095
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK1 BICDL2 ERC1 TRIP11 XPO5 ABI2 RABGAP1L NPC1L1 RABGEF1 XPO7

1.68e-0532111510GO:0031267
GeneOntologyMolecularFunctionGTPase binding

DOCK1 BICDL2 ERC1 TRIP11 XPO5 ABI2 RABGAP1L NPC1L1 RABGEF1 XPO7

4.46e-0536011510GO:0051020
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

HS6ST2 HS6ST1 HS6ST3

8.05e-05151153GO:0034483
GeneOntologyCellularComponentlaminin-11 complex

LAMB2 LAMC1

8.35e-0531112GO:0043260
MousePhenoabnormal heart ventricle outflow tract morphology

CYBB DOCK1 XPNPEP1 TRIP11 HOXA3 EHBP1L1 CC2D2A CHTOP

2.52e-0796948MP:0010224
MousePhenoabnormal semilunar valve morphology

CYBB DOCK1 XPNPEP1 HOXA3 EHBP1L1 CC2D2A CHTOP

3.89e-0697947MP:0002746
MousePhenoabnormal atrioventricular valve morphology

CYBB DOCK1 XPNPEP1 CC2D2A CHTOP

9.88e-0569945MP:0002745
MousePhenoabnormal heart valve morphology

CYBB DOCK1 XPNPEP1 HOXA3 EHBP1L1 CC2D2A CHTOP

1.13e-04163947MP:0000285
MousePhenoabnormal mesonephros morphology

LAMC1 XPNPEP1 RET EHBP1L1 CHTOP

1.21e-0472945MP:0008487
MousePhenoabnormal aortic valve morphology

CYBB XPNPEP1 HOXA3 EHBP1L1 CHTOP

1.21e-0472945MP:0002747
MousePhenoabnormal heart left ventricle outflow tract morphology

CYBB XPNPEP1 HOXA3 EHBP1L1 CHTOP

1.21e-0472945MP:0010429
MousePhenoabnormal heart atrium and ventricle connection

CYBB DOCK1 XPNPEP1 CC2D2A CHTOP

1.47e-0475945MP:0010435
DomainGOLGA6L

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

1.96e-0861144IPR026737
DomainHeparan_SO4-6-sulfoTrfase

HS6ST2 HS6ST1 HS6ST3

2.21e-0731143IPR010635
DomainGOLGA2L5

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

3.77e-06181144PF15070
DomainGolgin_A

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

3.77e-06181144IPR024858
DomainPAS_9

KCNH3 KCNH6 KCNH2

2.58e-05101143PF13426
DomainFoP_duplication

ALYREF CHTOP

3.69e-0521142SM01218
DomainFoP_C

ALYREF CHTOP

3.69e-0521142IPR025715
DomainFoP_duplication

ALYREF CHTOP

3.69e-0521142PF13865
DomainSPEC

MCF2L2 SPTBN5 SYNE2 MACF1

4.15e-05321144SM00150
DomainSpectrin/alpha-actinin

MCF2L2 SPTBN5 SYNE2 MACF1

4.15e-05321144IPR018159
DomainSulfotransfer_2

HS6ST2 HS6ST1 HS6ST3

4.68e-05121143PF03567
DomainSulfotransferase

HS6ST2 HS6ST1 HS6ST3

4.68e-05121143IPR005331
DomainPAS

NCOA3 KCNH3 KCNH6 KCNH2

5.30e-05341144PS50112
DomainPAS

NCOA3 KCNH3 KCNH6 KCNH2

5.30e-05341144IPR000014
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH3 KCNH6 KCNH2

7.68e-05141143IPR003938
DomainCH

SPEF2 SPTBN5 EHBP1L1 SYNE2 MACF1

8.37e-05731145PS50021
DomainCH-domain

SPEF2 SPTBN5 EHBP1L1 SYNE2 MACF1

9.53e-05751145IPR001715
DomainDUF3496

ANKRD26 CCDC144A

1.10e-0431142IPR021885
DomainK_chnl_volt-dep_ERG

KCNH6 KCNH2

1.10e-0431142IPR003967
DomainDUF3496

ANKRD26 CCDC144A

1.10e-0431142PF12001
DomainSpectrin

SPTBN5 SYNE2 MACF1

3.59e-04231143PF00435
DomainACTININ_2

SPTBN5 SYNE2 MACF1

3.59e-04231143PS00020
DomainACTININ_1

SPTBN5 SYNE2 MACF1

3.59e-04231143PS00019
DomainActinin_actin-bd_CS

SPTBN5 SYNE2 MACF1

3.59e-04231143IPR001589
DomainING

ING5 ING4

3.65e-0451142SM01408
DomainING_N_histone_binding

ING5 ING4

3.65e-0451142IPR024610
DomainING

ING5 ING4

3.65e-0451142PF12998
DomainING_fam

ING5 ING4

3.65e-0451142IPR028651
DomainPAS-assoc_C

KCNH3 KCNH6 KCNH2

4.08e-04241143IPR000700
DomainPAS

NCOA3 KCNH6 KCNH2

4.62e-04251143PF00989
DomainPAS_fold

NCOA3 KCNH6 KCNH2

4.62e-04251143IPR013767
DomainPAC

KCNH3 KCNH6 KCNH2

5.20e-04261143IPR001610
DomainPAC

KCNH3 KCNH6 KCNH2

5.20e-04261143PS50113
DomainPAC

KCNH3 KCNH6 KCNH2

5.20e-04261143SM00086
DomainKinesin-like

KIF13B RABGAP1L

5.45e-0461142IPR022164
DomainDUF3694

KIF13B RABGAP1L

5.45e-0461142PF12473
DomainCH

SPTBN5 EHBP1L1 SYNE2 MACF1

6.69e-04651144SM00033
DomainSpectrin_repeat

SPTBN5 SYNE2 MACF1

7.21e-04291143IPR002017
DomainCH

SPTBN5 EHBP1L1 SYNE2 MACF1

8.85e-04701144PF00307
Domain-

SPTBN5 EHBP1L1 SYNE2 MACF1

9.34e-047111441.10.418.10
DomainCNMP_BINDING_1

KCNH3 KCNH6 KCNH2

9.66e-04321143PS00888
DomainCNMP_BINDING_2

KCNH3 KCNH6 KCNH2

9.66e-04321143PS00889
DomainPAS

NCOA3 KCNH3 KCNH2

9.66e-04321143SM00091
DomaincNMP

KCNH3 KCNH6 KCNH2

1.15e-03341143SM00100
DomaincNMP_binding

KCNH3 KCNH6 KCNH2

1.15e-03341143PF00027
DomaincNMP-bd_dom

KCNH3 KCNH6 KCNH2

1.26e-03351143IPR000595
DomainCNMP_BINDING_3

KCNH3 KCNH6 KCNH2

1.26e-03351143PS50042
DomainBPI1

BPIFB1 BPIFB6

1.29e-0391142SM00328
DomainHTH_MYB

CDC5L SNAPC4

1.29e-0391142PS51294
DomainMyb_dom

CDC5L SNAPC4

1.29e-0391142IPR017930
DomaincNMP-bd-like

KCNH3 KCNH6 KCNH2

1.60e-03381143IPR018490
DomainLBP_BPI_CETP_C

BPIFB1 BPIFB6

1.61e-03101142PF02886
DomainLipid-bd_serum_glycop_C

BPIFB1 BPIFB6

2.34e-03121142IPR001124
DomainLBP_BPI_CETP

BPIFB1 BPIFB6

2.76e-03131142PF01273
DomainBPI/LBP/Plunc

BPIFB1 BPIFB6

2.76e-03131142IPR032942
DomainBactericidal_perm-incr_a/b_dom

BPIFB1 BPIFB6

2.76e-03131142IPR017943
DomainLipid-bd_serum_glycop_N

BPIFB1 BPIFB6

2.76e-03131142IPR017942
Domain-

KCNH3 KCNH6 KCNH2

3.14e-034811432.60.120.10
DomainRmlC-like_jellyroll

KCNH3 KCNH6 KCNH2

3.73e-03511143IPR014710
DomainLaminin_N

LAMB2 LAMC1

4.19e-03161142IPR008211
DomainIBN_N

XPO5 XPO7

4.19e-03161142SM00913
DomainLamNT

LAMB2 LAMC1

4.19e-03161142SM00136
DomainLAMININ_NTER

LAMB2 LAMC1

4.19e-03161142PS51117
DomainLaminin_N

LAMB2 LAMC1

4.19e-03161142PF00055
DomainImportin-beta_N

XPO5 XPO7

4.73e-03171142IPR001494
DomainIon_trans_dom

KCNH3 KCNH6 KCNH2 CATSPER4

5.25e-031141144IPR005821
DomainIon_trans

KCNH3 KCNH6 KCNH2 CATSPER4

5.25e-031141144PF00520
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIF13B ERC1 RALGPS2 ANKRD26 LAMC1 TAB2 ITPRID2 STIL TRIP11 ARFGEF3 VPS13D CCDC88A AMOT RABGAP1L SYNE2 MAD1L1 MACF1 PLEKHA5 RABGEF1 CSPP1 PLK4

2.03e-128611202136931259
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ERC1 ICE2 TAB2 TRIP11 RABL6 ARFGEF3 CCDC88A SYNE2 PLEKHA5 CSPP1 CCDC93

1.29e-092511201129778605
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ERC1 TAB2 SMG5 ZNRF3 XPO5 AMOT SYNE2 MACF1 PLEKHA5 CDC5L

6.56e-092251201012168954
Pubmed

Expression of cytokeratin 7, 20, 14 in urothelial carcinoma and squamous cell carcinoma of the Egyprian urinary bladder cancer.

KRT7 KRT14 KRT20

4.01e-083120325643514
Pubmed

Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis.

HS6ST2 HS6ST1 HS6ST3

4.01e-083120315499561
Pubmed

Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases.

HS6ST2 HS6ST1 HS6ST3

4.01e-083120312611590
Pubmed

The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine.

HS6ST2 HS6ST1 HS6ST3

4.01e-083120310644753
Pubmed

Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.

HS6ST2 HS6ST1 HS6ST3

4.01e-083120323223449
Pubmed

Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation.

HS6ST2 HS6ST1 HS6ST3

4.01e-083120316326709
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

TAB2 XPNPEP1 COLEC12 CCDC88A ABI2 MACF1 CDC5L CCDC93

5.84e-08151120817043677
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FAM184B KCNH3 CNOT6 ARFGEF3 CCDC88A XPO5 MACF1

7.35e-08103120710574462
Pubmed

Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.

HS6ST2 HS6ST1 HS6ST3

1.60e-074120315226404
Pubmed

Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice.

HS6ST2 HS6ST1 HS6ST3

1.60e-074120321951307
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

KIF13B NCOA3 ERC1 NIPSNAP1 RALGPS2 TRIP11 GTF3C4 CNOT6 CCDC88A XPO5 AMOT RABGAP1L PLEKHA5 ALYREF RABGEF1 CSPP1 CCDC93 CCDC144A

6.69e-0713211201827173435
Pubmed

A human MAP kinase interactome.

DOCK1 KRT14 ING5 LAMB2 NCKAP5 ITPRID2 CCDC88A CEP250 KRT20 MACF1 PLEKHA5

1.05e-064861201120936779
Pubmed

Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.

HS6ST2 HS6ST1 HS6ST3

1.39e-067120320410206
Pubmed

Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality.

HS6ST2 HS6ST1 HS6ST3

2.22e-068120317405882
Pubmed

Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate.

HS6ST2 HS6ST1 HS6ST3

3.31e-069120321357686
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ANKRD26 TAB2 TRIP11 RABL6 CCDC88A AMOT MACF1 PLEKHA5

3.89e-06263120834702444
Pubmed

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

KCNH3 KCNH6 KCNH2

4.72e-0610120326503718
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KIF13B KRT14 ERC1 ANKRD26 TAB2 ITPRID2 TRIP11 ARFGEF3 CCDC88A SUPT6H MACF1

6.47e-065881201138580884
Pubmed

Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.

HS6ST2 HS6ST1 HS6ST3

6.48e-0611120315944372
Pubmed

Involvement of heparan sulfate 6-O-sulfation in the regulation of energy metabolism and the alteration of thyroid hormone levels in male mice.

HS6ST2 HS6ST1 HS6ST3

6.48e-0611120323690091
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DOCK1 ERC1 ICE2 ANKRD26 TAB2 XPNPEP1 RABL6 CCDC88A XPO5 FANCI MACF1 PLEKHA5

6.57e-067081201239231216
Pubmed

Identification of potential bladder progenitor cells in the trigone.

KRT7 KRT14 KRT20

8.61e-0612120324992712
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

HS6ST2 HS6ST1 HS6ST3

8.61e-0612120312460940
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ANKRD26 LAMC1 TAB2 TRIP11 SUPT6H AMOT SYNE2 MACF1 RABGEF1 ATP2A1

9.27e-064971201023414517
Pubmed

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.

KRT14 HS6ST2 LAMB2 HS6ST1 HS6ST3

9.34e-0681120539217171
Pubmed

CK7+/CK20- Merkel cell carcinoma presenting as inguinal subcutaneous nodules with subsequent epidermotropic metastasis.

KRT7 KRT20

1.18e-052120220574624
Pubmed

Cytokeratin 7 and 20 expression in gallbladder carcinoma.

KRT7 KRT20

1.18e-052120221574103
Pubmed

Invariant chain processing is independent of cathepsin variation between primary human B cells/dendritic cells and B-lymphoblastoid cells.

CD74 CTSG

1.18e-052120221543057
Pubmed

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.

LAMB2 LAMC1

1.18e-05212022922051
Pubmed

ANKRD26-RET - A novel gene fusion involving RET in papillary thyroid carcinoma.

ANKRD26 RET

1.18e-052120231425920
Pubmed

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.

STIL PLK4

1.18e-052120225342035
Pubmed

Expression pattern of CK7 and CK20 in nasal polyps, at patients with chronic rhinosinusitis with nasal polyposis.

KRT7 KRT20

1.18e-052120222119824
Pubmed

Altered expression of CK7 and CK20 in preneoplastic and neoplastic lesions in ulcerative colitis.

KRT7 KRT20

1.18e-052120218092953
Pubmed

Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling.

HS6ST2 HS6ST1

1.18e-052120224563483
Pubmed

Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties.

HS6ST2 HS6ST1

1.18e-052120212492399
Pubmed

Identical cytokeratin expression pattern CK7+/CK20- in esophageal and cardiac cancer: etiopathological and clinical implications.

KRT7 KRT20

1.18e-052120214631371
Pubmed

Aberrant keratin 7 and 20 expression in triple-negative carcinoma of the breast.

KRT7 KRT20

1.18e-052120226670478
Pubmed

CK7+/CK20- immunoexpression profile is typical of salivary gland neoplasia.

KRT7 KRT20

1.18e-052120217593078
Pubmed

Changing pattern of cytokeratin 7 and 20 expression from normal epithelium to intestinal metaplasia of the gastric mucosa and gastroesophageal junction.

KRT7 KRT20

1.18e-052120211962749
Pubmed

Cytokeratin 7 and cytokeratin 20 expression in colorectal adenocarcinomas.

KRT7 KRT20

1.18e-052120221282015
Pubmed

Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine.

KRT7 KRT20

1.18e-052120215371952
Pubmed

Functional analysis of a mouse brain Elk-type K+ channel.

KCNH3 KCNH2

1.18e-052120210191308
Pubmed

Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers.

KRT7 KRT20

1.18e-052120235390310
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

KRT14 NIPSNAP1 LAMB2 LAMC1 ITPRID2 SUPT6H AMOT SYNE2 MACF1 ALYREF CDC5L PHIP CHTOP XPO7

1.25e-0510241201424711643
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOA3 TRIML2 ERC1 LAMC1 GTF3C4 CCDC88A AMOT PLEKHA5 ARL14EP

1.55e-05418120934709266
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

ERC1 TAB2 AMOT PLK4

2.53e-0549120431762063
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ERC1 NIPSNAP1 RALGPS2 ANKRD26 GTF3C4 AMOT PLEKHA5 RABGEF1 CSPP1

2.58e-05446120924255178
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

ANKRD26 TAB2 STIL XPO5 PLEKHA5 CSPP1

2.78e-05169120631462741
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LAMB2 SMG5 EML3 KCNH3 FOCAD RABL6 EHBP1L1 ZNRF3 KCNH2 FANCI MAD1L1 PAXIP1 NLRC5 SNAPC4

2.89e-0511051201435748872
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF13B NCOA3 ERC1 TRIP11 CCDC88A ABI2 SYNE2 MAD1L1 MACF1 PLEKHA5 ALYREF RABGEF1 CDC5L

2.96e-059631201328671696
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

ERC1 RALGPS2 EML3 CEP250 PLEKHA5 RABGEF1 CDC5L

3.09e-05255120715324660
Pubmed

Mapping interactions between mRNA export factors in living cells.

ALYREF CHTOP

3.53e-053120223826332
Pubmed

Multiple exportins influence thyroid hormone receptor localization.

XPO5 XPO7

3.53e-053120225911113
Pubmed

Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.

KCNH6 KCNH2

3.53e-053120214643686
Pubmed

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

STIL PLK4

3.53e-053120229712910
Pubmed

Differential expression of CK7, CK20, CDX2 in intestinal and pancreatobiliary types of preriampullary carcinoma.

KRT7 KRT20

3.53e-053120235074964
Pubmed

Loss of Rad51c accelerates tumourigenesis in sebaceous glands of Trp53-mutant mice.

RAD51C KRT14

3.53e-053120225270124
Pubmed

Superficial cell differentiation during embryonic and postnatal development of mouse urothelium.

KRT7 KRT20

3.53e-053120216973199
Pubmed

Rad51c- and Trp53-double-mutant mouse model reveals common features of homologous recombination-deficient breast cancers.

RAD51C KRT14

3.53e-053120226820992
Pubmed

Direct interaction between CEP85 and STIL mediates PLK4-driven directed cell migration.

STIL PLK4

3.53e-053120232107292
Pubmed

EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5.

ING5 ING4

3.53e-053120221177815
Pubmed

Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells.

STIL PLK4

3.53e-053120230197118
Pubmed

CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis.

STIL PLK4

3.53e-053120227112295
Pubmed

Histomorphologic and molecular features of pouch and peripouch adenocarcinoma: a comparison with ulcerative colitis-associated adenocarcinoma.

KRT7 KRT20

3.53e-053120222895272
Pubmed

Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.

LAMB2 LAMC1

3.53e-05312027698745
Pubmed

Aberrant pattern of the cytokeratin 7/cytokeratin 20 immunophenotype in colorectal adenocarcinomas with BRAF mutations.

KRT7 KRT20

3.53e-053120222361037
Pubmed

Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.

KCNH6 KCNH2

3.53e-053120235818223
Pubmed

Laminin-11.

LAMB2 LAMC1

3.53e-053120210481268
Pubmed

Cell-cycle-regulated expression of STIL controls centriole number in human cells.

STIL PLK4

3.53e-053120222349698
Pubmed

Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells.

CCDC88A KCNH2

3.53e-053120237923359
Pubmed

Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.

LAMB2 LAMC1

3.53e-05312026209134
Pubmed

HERG K(+) currents in human prolactin-secreting adenoma cells.

KCNH6 KCNH2

3.53e-053120212634931
Pubmed

The PLK4-STIL-SAS-6 module at the core of centriole duplication.

STIL PLK4

3.53e-053120227911707
Pubmed

The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody.

KRT7 KRT20

3.53e-053120222268990
Pubmed

Expression of cytokeratin 7/20 and Ki67 in Helicobacter pylori-associated gastritis and intestinal metaplasia.

KRT7 KRT20

3.53e-053120239078783
Pubmed

Biomarkers CDX2, CK20, CK7 in Schoolchildren with Gastritis in the Realization of Familial Predisposition of Stomach Cancer.

KRT7 KRT20

3.53e-053120234853972
Pubmed

CDX2, cytokeratins 7 and 20 immunoreactivity in rectal adenocarcinoma.

KRT7 KRT20

3.53e-053120219098678
Pubmed

Laminin-121--recombinant expression and interactions with integrins.

LAMB2 LAMC1

3.53e-053120220566382
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

NCOA3 NIPSNAP1 GTF3C4 SUPT6H FANCI ING4 ALYREF CDC5L PHIP

3.81e-05469120927634302
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

TMOD4 XPO5 UNC45B AMOT FANCI SYNE2 MAD1L1 PSKH2

3.97e-05363120825036637
Pubmed

Centriole signaling restricts hepatocyte ploidy to maintain liver integrity.

ANKRD26 PLK4

7.05e-054120235981754
Pubmed

Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).

LAMB2 LAMC1

7.05e-054120224951930
Pubmed

Regulation and Function of Laminin A5 during Mouse and Human Decidualization.

LAMB2 LAMC1

7.05e-054120235008625
Pubmed

Hbo1 Links p53-dependent stress signaling to DNA replication licensing.

ING5 ING4

7.05e-054120217954561
Pubmed

STIL is required for centriole duplication in human cells.

STIL PLK4

7.05e-054120222349705
Pubmed

Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.

HS6ST2 HS6ST1

7.05e-054120223074159
Pubmed

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

ING5 ING4

7.05e-054120212750254
Pubmed

Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study.

TNFSF13 SPATC1L

7.05e-054120228849223
Pubmed

Proteoglycans and their roles in brain cancer.

HS6ST2 HS6ST1

7.05e-054120223281850
Pubmed

Anatomical studies of the mouse genital tubercle.

KRT7 KRT14

7.05e-054120215086023
Pubmed

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.

STIL PLK4

7.05e-054120226188084
Pubmed

Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation.

HS6ST2 HS6ST1

7.05e-054120229104277
Pubmed

Changes in laminin isoforms associated with brain tumor invasion and angiogenesis.

LAMB2 LAMC1

7.05e-054120216146715
Pubmed

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.

LAMB2 LAMC1

7.05e-05412028034675
Pubmed

A protein interaction landscape of breast cancer.

RAD51C BPIFB1 SMG5 ITPRID2 TRIP11 GTF3C4 XPO5 FANCI MACF1 XPO7

7.27e-056341201034591612
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 KRT7 KRT14 LAMC1 ITPRID2 XPO5

7.51e-05202120633005030
Pubmed

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.

KRT14 HS6ST2 HS6ST1

7.69e-0524120334653670
InteractionYWHAH interactions

KIF13B NCOA3 ERC1 RALGPS2 ANKRD26 TAB2 ITPRID2 STIL TRIP11 EML3 ARFGEF3 SLX9 VPS13D CCDC88A ABI2 KCNH2 AMOT RABGAP1L SYNE2 MAD1L1 CC2D2A MACF1 PLEKHA5 RABGEF1 ARL14EP CSPP1 PLK4

1.61e-10110211827int:YWHAH
InteractionYWHAG interactions

KIF13B ERC1 RALGPS2 ANKRD26 TAB2 ITPRID2 TRIP11 EML3 VPS13D CCDC88A AMOT CEP250 RABGAP1L SYNE2 MAD1L1 ING4 MACF1 PLEKHA5 RABGEF1 ARL14EP CDC5L CSPP1 PLK4

8.02e-07124811823int:YWHAG
InteractionSASS6 interactions

ERC1 ANKRD26 STIL TRIP11 ABI2 CEP250 CSPP1 PLK4

4.42e-061591188int:SASS6
InteractionCCHCR1 interactions

TRIML2 ING5 TSGA10 ABI2 RABGAP1L MAD1L1 RABGEF1 GOLGA6L9 CCDC93

8.25e-062291189int:CCHCR1
InteractionDISC1 interactions

TSGA10 LAMC1 XPNPEP1 STIL TRIP11 CCDC88A ABI2 AMOT MACF1 ALYREF CDC5L SPATC1L

8.28e-0642911812int:DISC1
InteractionPCM1 interactions

FAM184B KRT14 ERC1 ING5 ANKRD26 SMG5 ITPRID2 STIL ABI2 CEP250 CC2D2A CSPP1

9.30e-0643411812int:PCM1
InteractionMIB1 interactions

ANKRD26 TAB2 AZI2 STIL RET XPO5 CEP250 PLEKHA5 CSPP1 PLK4

9.39e-0629511810int:MIB1
InteractionNDC80 interactions

ERC1 ANKRD26 FOCAD XPO5 AMOT CEP250 SYNE2 MAD1L1 CDC5L CSPP1

1.53e-0531211810int:NDC80
InteractionEXOC1 interactions

COLEC12 CCDC88A RABGAP1L MACF1 RABGEF1 CDC5L CCDC93

2.14e-051431187int:EXOC1
InteractionVPS33B interactions

ITPRID2 RABL6 ARFGEF3 CCDC88A SYNE2 PLEKHA5 CDC5L CSPP1

2.27e-051991188int:VPS33B
InteractionYWHAQ interactions

KIF13B NCOA3 ERC1 RALGPS2 ANKRD26 TAB2 ITPRID2 TRIP11 EML3 VPS13D CCDC88A CEP250 MACF1 CD74 PLEKHA5 RABGEF1 ARL14EP CDC5L PLK4

2.60e-05111811819int:YWHAQ
InteractionNUP62 interactions

TRIML2 ERC1 CCDC88A ABI2 CEP250 SYNE2 KRT20 CCDC93 XPO7

3.32e-052731189int:NUP62
InteractionKCNH4 interactions

KCNH3 KCNH6 KCNH2

4.14e-05121183int:KCNH4
InteractionSFN interactions

KIF13B RALGPS2 ANKRD26 TAB2 ITPRID2 TRIP11 CCDC88A AMOT RABGAP1L MACF1 PLEKHA5 RABGEF1 PLK4 CHTOP

5.37e-0569211814int:SFN
InteractionGARRE1 interactions

SMG5 STIL CNOT6 ABI2 AMOT CSPP1 PHIP

5.77e-051671187int:GARRE1
InteractionSNAPIN interactions

TRIML2 LAMC1 ABI2 C20orf202 KRT20 MACF1 RABGEF1

6.22e-051691187int:SNAPIN
InteractionINSYN1 interactions

ERC1 TRIP11 EML3 ABI2 RABGAP1L RABGEF1 CCDC93

6.22e-051691187int:INSYN1
InteractionYWHAZ interactions

KIF13B ERC1 HS6ST2 RALGPS2 ANKRD26 LAMC1 TAB2 ITPRID2 EML3 VPS13D CCDC88A ABI2 SYNE2 MACF1 CD74 PLEKHA5 RABGEF1 ARL14EP CDC5L PLK4

7.74e-05131911820int:YWHAZ
InteractionYWHAB interactions

KIF13B ERC1 RALGPS2 ANKRD26 ITPRID2 TRIP11 EML3 VPS13D CCDC88A ABI2 AMOT MACF1 CD74 PLEKHA5 RABGEF1 ARL14EP PLK4

8.55e-05101411817int:YWHAB
InteractionPCNT interactions

ING5 STIL TRIP11 AMOT MACF1 CDC5L CSPP1 PLK4

8.79e-052411188int:PCNT
InteractionKRT75 interactions

KRT7 KRT14 TRIML2 ABI2 AMOT KRT20 GOLGA6L9

9.57e-051811187int:KRT75
InteractionFBXO42 interactions

KIF13B KRT14 ERC1 TAB2 TRIP11 ARFGEF3 CCDC88A MACF1

1.45e-042591188int:FBXO42
InteractionPHLDB3 interactions

RABGAP1L RABGEF1 SNAPC4 CHTOP CCDC93

1.51e-04861185int:PHLDB3
InteractionATF7IP interactions

KRT7 NPR1 LAMC1 CEP250 MACF1 ARL14EP

1.63e-041381186int:ATF7IP
InteractionMETTL21C interactions

GTF3C4 CCDC88A MAD1L1

1.77e-04191183int:METTL21C
InteractionJADE2 interactions

ING5 CCDC88A ING4 CCDC93

1.78e-04481184int:JADE2
InteractionPLEC interactions

KRT14 SPEF2 NIPSNAP1 TSGA10 CCDC88A SYNE2 MACF1 PLEKHA5 CDC5L SPATC1L

2.21e-0443011810int:PLEC
InteractionWASHC1 interactions

TAOK3 ABI2 KRT20 RABGEF1 CCDC93

2.29e-04941185int:WASHC1
InteractionLINC02910 interactions

KIF13B FOCAD RABL6 SLX9 CDC5L

2.41e-04951185int:LINC02910
InteractionCEP350 interactions

NCKAP5 STIL AMOT CEP250 PLEKHA5 PLK4

2.46e-041491186int:CEP350
InteractionTRAF3IP1 interactions

TAB2 ABI2 MACF1 CDC5L CCDC93

2.53e-04961185int:TRAF3IP1
InteractionKRT19 interactions

KRT7 KRT14 ERC1 ANKRD26 ABI2 AMOT PLEKHA5 CSPP1

2.58e-042821188int:KRT19
InteractionKRT24 interactions

TRIML2 ABI2 AMOT KRT20

2.82e-04541184int:KRT24
InteractionCEP250 interactions

CCDC88A SUPT6H AMOT CEP250 FAM167A PLEKHA5 ALYREF PLK4

2.90e-042871188int:CEP250
InteractionOIP5 interactions

KRT14 ING5 ABI2 RABGAP1L ING4 RABGEF1 CCDC93

2.92e-042171187int:OIP5
Cytoband15q25.2

GOLGA6L4 GOLGA6L10 GOLGA6L9

1.94e-0443119315q25.2
GeneFamilyExportins

XPO5 XPO7

2.81e-047672547
GeneFamilySulfotransferases, membrane bound

HS6ST2 HS6ST1 HS6ST3

3.45e-0437673763
GeneFamilyPotassium voltage-gated channels

KCNH3 KCNH6 KCNH2

4.36e-0440673274
GeneFamilyLaminin subunits

LAMB2 LAMC1

8.72e-0412672626
GeneFamilyBPI fold containing

BPIFB1 BPIFB6

1.57e-0316672456
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 GTF3C4

1.77e-0317672486
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

RAD51C FANCI

2.46e-0320672548
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 PAXIP1

3.84e-0325672775
GeneFamilyKeratins, type I

KRT14 KRT20

4.81e-0328672608
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

NCOA3 ERC1 ICE2 RALGPS2 ANKRD26 TAB2 AZI2 MFN1 CCDC88A HECTD2 CEP250 SYNE2 CC2D2A MACF1 PLEKHA5 ARL14EP SNAPC4 PHIP

2.05e-0778011518Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPEF2 ANKRD26 STIL FANCI CC2D2A CCDC171 CSPP1 PLK4

1.04e-081571198410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 KRT7 KRT14 HOXA3 ANGPTL2 FAM167A

9.29e-061811196a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 KRT7 KRT14 HOXA3 ANGPTL2 FAM167A

9.29e-061811196504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 KRT7 KRT14 HOXA3 ANGPTL2 FAM167A

9.29e-061811196a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB TNFSF13 SLC40A1 CLEC4F FAM167A CD74

9.29e-061811196a93df1ba23d5b5f249491d69d12bfc0e274dafcf
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LAMB2 LAMC1 TAOK3 CERCAM PLEKHA5 CSPP1

1.26e-05191119639ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 NCKAP5 RABGAP1L SYNE2 MACF1 PLEKHA5

1.30e-051921196e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBB SLC40A1 CLEC4F CCDC88A CD74 CTSG

1.55e-051981196af682919a874d60f579e854c274dc47063015ea9
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

NPR1 SPEF2 LAMB2 NCKAP5 ZNRF3 MACF1

1.59e-05199119611c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellASK452-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

KRT7 LAMB2 NCKAP5 SLC40A1 ANGPTL2 SYNE2

1.59e-05199119648cafe44951908d03f3c6f3e185e9cbb86fb5b3b
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NPR1 SPEF2 NCKAP5 ITPRID2 SYNE2 MACF1

1.64e-052001196a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

TAB2 RET VPS13D AMOT PLEKHA5

3.02e-0513411952647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC40A1 UNC45B FAM167A CD74 ATP2A1

5.02e-05149119558c1ac5a46898021224b9cb1483a0c58554bc4fb
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC40A1 UNC45B FAM167A CD74 ATP2A1

6.06e-05155119592dc029ed8b197b2d3ab73719a36545d86b26cb1
ToppCellVE-Treg-naive_CD4|VE / Condition, Cell_class and T cell subcluster

NIPSNAP1 ANKRD26 GOLGA6L4 KCNH2 SYNE2

6.24e-0515611956501baf73616e702946de9fb13d267e30a68888b
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF13B MFN1 GOLGA6L10 GOLGA6L9 CSPP1

6.43e-0515711954183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 KIF13B LRRN3 FANCI CERCAM

7.25e-051611195140b3c7077947c541cff54f6754e2df968345f4d
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CELF5 NPR1 TNFSF13 HOXA3 ABI2

7.68e-051631195bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB RALGPS2 RABGAP1L FAM167A CD74

8.37e-0516611954b31d2755108b2815316411a38bfb11fd30ef98a
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

STIL KCNH3 HS6ST3 ATP2A1

8.74e-05871194fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CELF5 NPR1 TNFSF13 HOXA3 ABI2

8.86e-05168119563437b3c3a66f953eaed600965ab193f9cc49da2
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SLC40A1 CLEC4F FAM167A CD74

9.11e-05169119544d841fd997a6f26104f16cd00223ecce8352f43
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SLC40A1 CLEC4F FAM167A CD74

9.11e-0516911950f5e737b265ba333275a0cd289dab029a1542075
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SLC40A1 CLEC4F FAM167A CD74

9.11e-051691195aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 NLRC5 ALYREF HSD17B8 CCDC93

9.90e-051721195d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF13 SLC40A1 HOXA3 CLEC4F CCDC171

9.90e-0517211951f335ccb92b22d0412954e8fc3af212f96410b67
ToppCellILEUM-inflamed-(4)_Mast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LGALS12 RET KCNH2 HS6ST1 CTSG

9.90e-051721195be82f749f4b1049ae8832facc052082cf5463c11
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF13 SLC40A1 HOXA3 CLEC4F CCDC171

9.90e-051721195bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CASS4 BICDL2 FOCAD XPO5 PLK4

9.90e-051721195da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellILEUM-inflamed-(4)_Mast_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LGALS12 RET KCNH2 HS6ST1 CTSG

9.90e-0517211957185b28282412f3a464b2a8ad5605475a1a31358
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS12 RET KCNH2 HS6ST1 CTSG

1.02e-041731195a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

CYBB TNFSF13 LGALS12 SLC40A1 CTSG

1.04e-0417411951e289b26e2c29dbad15b712a999b96c391a26129
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB TNFSF13 SLC40A1 CLEC4F CD74

1.04e-041741195dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B AZI2 TRIP11 CCDC88A MACF1

1.10e-041761195749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSGA10 LGALS12 KCNH2 PAXIP1 CTSG

1.10e-0417611950d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCellwk_20-22-Hematologic-Myeloid-Promyelocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

WDR97 FANCI CTSG CCDC93 CCDC144A

1.10e-041761195ee33d7077a92c1fd371081e7c990c7266e711957
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSGA10 EML3 AMOT PAXIP1 ALYREF

1.13e-041771195164ffbbf798defa3728197deb1a14b661490e525
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SLC40A1 CLEC4F FAM167A CD74

1.13e-04177119543883b65b1e03043a24fc40c84c50bac81960c12
ToppCelldroplet-Lung-LUNG-30m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SLC40A1 CLEC4F FAM167A CD74

1.13e-0417711959de6a82b7fb72d20361947f7ac95bb1fa73fc2ff
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LAMB2 NCKAP5 ITPRID2 RET KCNH2

1.13e-04177119599500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB SLC40A1 CLEC4F FAM167A CD74

1.16e-041781195c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BPIFB1 STIL CC2D2A CCDC171 PLK4

1.19e-041791195d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BPIFB1 STIL CC2D2A CCDC171 PLK4

1.19e-041791195e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB SLC40A1 CLEC4F FAM167A CD74

1.19e-04179119513d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMOD4 LAMB2 NCKAP5 RET KCNH2

1.22e-0418011958af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS12 RET KCNH2 HS6ST1 CTSG

1.22e-0418011952658a6be43d6d94767b4fc5af2d8632469a8a979
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 LAMB2 ITPRID2 HOXA3 UNC45B

1.29e-041821195c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 LAMB2 ITPRID2 HOXA3 UNC45B

1.29e-041821195d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LAMB2 NCKAP5 RET COLEC12 KCNH2

1.32e-041831195ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB BEST1 EHBP1L1 CD74 ALYREF

1.32e-041831195cff3197e9ff401362501db2317c86adc6d24b595
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB BEST1 EHBP1L1 CD74 ALYREF

1.32e-041831195f803dd2881ceaed6327e21a1a51bc3d3ccf4b5f8
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB BEST1 EHBP1L1 CD74 ALYREF

1.32e-0418311954bd6883daf2dbe8c1b49b776b48d41f9890d1cb4
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFSF13 LGALS12 FAM167A KRT20 SNAPC4

1.32e-0418311956e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 KIF13B BEST1 NCKAP5 CERCAM

1.32e-04183119593213124e55d1b673dd345188caf8b5bd31d99fe
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-041851195ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-0418511953beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-041851195ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 NIPSNAP1 KCNH6 TAOK3 PLEKHA5

1.39e-0418511951d874608aa2062024323512f68889219471b2f00
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-0418511959aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-04185119542939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-041851195f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNFSF13 SLC40A1 COLEC12 CD74 HSD17B8

1.39e-0418511957a3612520ae4f0cd61480eadba31eecce001419d
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 TAOK3 ZNRF3 HS6ST1 PLEKHA5

1.43e-041861195de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 TAOK3 ZNRF3 HS6ST1 PLEKHA5

1.43e-0418611950b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LAMC1 GTF3C4 AMOT CCDC171 XPO7

1.43e-0418611955cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT7 RET ARFGEF3 KCNH6 NPC1L1

1.43e-041861195fcabebdfbf1b1dbb35ce2b3c53a60d2b1aed8e6c
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMOD4 LAMB2 NCKAP5 RET KCNH2

1.46e-0418711953e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

KRT7 LAMB2 NCKAP5 ITPRID2 FAM167A

1.46e-0418711953a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMOD4 LAMB2 NCKAP5 RET KCNH2

1.54e-0418911956011b747e27d61d222380a7bffdd921a68e9b657
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STIL HECTD2 FANCI CCDC171 PLK4

1.58e-0419011957be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMB2 NCKAP5 RET COLEC12 KCNH2

1.58e-04190119505a2c3549b68f49081723bf35db14974274419d5
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

LAMB2 LAMC1 CERCAM PLEKHA5 CSPP1

1.58e-0419011952434b8ad2976eab7d9147012c28454ab29670709
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCOA3 HS6ST2 RET CD74 HS6ST3

1.58e-0419011951bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 NCKAP5 SLC40A1 ANGPTL2 FAM167A

1.62e-041911195a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B HS6ST2 LAMC1 TRIP11 PLEKHA5

1.62e-0419111957d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 BEST1 NCKAP5 CERCAM CD74

1.62e-041911195a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFSF13 AZI2 COLEC12 CCDC88A CD74

1.65e-041921195b9d6cf6068ffa104968f4944cbf8af6faa2b8942
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 RET ANGPTL2 CERCAM

1.65e-041921195beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CASS4 LAMC1 SLC40A1 LRRN3 MACF1

1.65e-04192119562904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CASS4 SLC40A1 HOXA3 COLEC12 MACF1

1.70e-0419311959f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBB LGALS12 NLRC5 CD74 CTSG

1.70e-04193119535998200890fef12e7f4a3dc65eca1c30d19fa93
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CASS4 NCKAP5 SLC40A1 LRRN3 MACF1

1.70e-0419311955896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellB_cells-Activate_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CYBB NCOA3 RALGPS2 FAM167A CD74

1.70e-041931195b6da81920cf2e55f87ec8d4b2b5530cbf7ba2155
ToppCellC_06|World / shred on cell type and cluster

KRT7 BPIFB1 ODAM SYNE2 CD74

1.74e-0419411955cb42e09f380c4468cdc603ec0c3de35eadd3213
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

STIL FANCI CCDC171 CSPP1 PLK4

1.74e-0419411955dffa578149104dda33774361e9e77b227b5f1ce
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBB SLC40A1 CLEC4F CCDC88A CD74

1.74e-0419411957c7091de47359760003e910cfbe63db5c99410d6
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBB CASS4 SLC40A1 CLEC4F CD74

1.74e-0419411958e2819a9d0529f7b2de1a7c1190575175d6173ee
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB SLC40A1 COLEC12 CCDC88A CD74

1.74e-04194119548c37251518f96524807b5bd1bbc2820637666ad
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CASS4 SLC40A1 HOXA3 COLEC12 MACF1

1.74e-04194119571d3c7448b1734de54187f902f65649f9283bd4c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 ERC1 SPEF2 NCKAP5 MACF1

1.74e-0419411950b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB SLC40A1 COLEC12 CCDC88A CD74

1.74e-0419411957b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYBB SLC40A1 COLEC12 CCDC88A CD74

1.74e-041941195435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

STIL FANCI CCDC171 PLK4 PHIP

1.74e-041941195dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SPEF2 BPIFB1 ARFGEF3 SYNE2 PLEKHA5

1.78e-041951195fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCOA3 CCDC88A SYNE2 CD74 CCDC144A

1.78e-041951195cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SPEF2 BPIFB1 ARFGEF3 SYNE2 PLEKHA5

1.78e-04195119521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 KRT7 BPIFB1 SLC40A1 AMOT

1.78e-0419511953f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SPEF2 BPIFB1 ARFGEF3 SYNE2 PLEKHA5

1.78e-041951195eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH3 HOXA3 LRRN3 ANGPTL2 FAM167A

1.78e-041951195ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B TMOD4 TRIP11 COLEC12 PLEKHA5

1.78e-0419511955c86fddd6d0530beecf45ea5ba6b823123847696
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

FAM114A2 SMG5 TRIP11 EML3 GTF3C4 MFN1 RABL6 CTSG CHTOP

8.36e-0719711791148_DN
DrugErythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A

ERC1 LAMB2 TRIP11 VPS13D KCNH2 SUPT6H SNAPC4 CSPP1

7.71e-0619511785329_UP
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; HL60; HT_HG-U133A

NCOA3 NIPSNAP1 SMG5 MFN1 EHBP1L1 ABI2 MACF1 XPO7

8.00e-0619611781315_DN
DrugWAY-123,398

KCNH3 KCNH6 KCNH2

1.55e-05101173CID000132160
DrugN-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine

KCNH6 KCNH2

2.62e-0521172ctd:C531033
DrugEGDA

KRT7 KRT14 KRT20

5.75e-05151173CID000008121
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A

TAB2 SMG5 EML3 VPS13D SNAPC4 CSPP1 PLK4

5.77e-0519011776718_DN
DrugPhensuximide [86-34-0]; Down 200; 21.2uM; MCF7; HT_HG-U133A

KIF13B TSGA10 EHBP1L1 MACF1 CSPP1 PLK4 CCDC93

6.58e-0519411773521_DN
DrugMethylergometrine maleate [113-42-8]; Up 200; 8.8uM; MCF7; HT_HG-U133A

TRIP11 EML3 VPS13D KCNH2 CSPP1 PLK4 CCDC93

6.58e-0519411775303_UP
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A

FAM114A2 SMG5 RET EML3 RABGAP1L SNAPC4 PLK4

6.80e-0519511776979_DN
DrugTolfenamic acid [13710-19-5]; Down 200; 15.2uM; PC3; HT_HG-U133A

LAMB2 SMG5 TRIP11 VPS13D CEP250 CHTOP CCDC93

7.02e-0519611776354_DN
DrugHarmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A

TSGA10 ANKRD26 EML3 EHBP1L1 KCNH2 CEP250 PLK4

7.25e-0519711772892_DN
DrugDNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A

ERC1 ANKRD26 TRIP11 EHBP1L1 CCDC88A CEP250 CDC5L

7.25e-0519711777543_DN
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A

DOCK1 ITPRID2 EML3 VPS13D KCNH2 ING4 MACF1

7.25e-0519711772768_DN
DrugTobramycin [32986-56-4]; Down 200; 8.6uM; HL60; HT_HG-U133A

NCOA3 MFN1 EHBP1L1 CCDC88A RABGAP1L PLK4 XPO7

7.25e-0519711772481_DN
DrugCefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; PC3; HT_HG-U133A

TSGA10 EML3 SPTBN5 ODAM CEP250 RABGAP1L CSPP1

7.49e-0519811775868_UP
DrugStreptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A

KIF13B NCOA3 EML3 KCNH6 EHBP1L1 SNAPC4 CSPP1

7.49e-0519811775837_UP
DrugReserpine [50-55-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A

ANKRD26 RET VPS13D CEP250 RABGAP1L ING4 CCDC93

7.73e-0519911773341_DN
DrugVinpocetine [42971-09-5]; Down 200; 11.4uM; HL60; HG-U133A

CYBB RAD51C AZI2 EML3 CCDC88A MACF1 SNAPC4

7.73e-0519911771557_DN
DrugTubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; HL60; HG-U133A

NCOA3 EML3 VPS13D CCDC88A ABI2 SNAPC4 PLK4

7.73e-0519911771738_DN
DrugChloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; HL60; HT_HG-U133A

CASS4 BEST1 ANKRD26 MFN1 ABI2 KRT20 PLK4

7.73e-0519911773011_DN
Drugksc-8-189

RET PLK4

7.83e-0531172CID000001400
Diseaseshort QT syndrome (implicated_via_orthology)

KCNH6 KCNH2

4.51e-0531152DOID:0050793 (implicated_via_orthology)
Diseasesquamous cell carcinoma (implicated_via_orthology)

ING5 ING4

4.51e-0531152DOID:1749 (implicated_via_orthology)
Diseaseheart conduction disease (implicated_via_orthology)

KCNH6 MMEL1 KCNH2

2.63e-04321153DOID:10273 (implicated_via_orthology)
Diseasearabitol measurement

NCOA3 GTF3C4

3.12e-0471152EFO_0800148
Diseasevital capacity

NCOA3 FAM184B BEST1 ERC1 RALGPS2 TPRX2 TRIP11 EML3 KCNH3 HOXA3 MAD1L1 CDC5L SNAPC4 CCDC171

3.28e-04123611514EFO_0004312
Diseasemelanoma (implicated_via_orthology)

ING5 ING4

4.15e-0481152DOID:1909 (implicated_via_orthology)
DiseaseColorectal Carcinoma

TNFSF13 MCF2L2 LAMC1 RET MFN1 ODAM KRT20 ING4 PHIP CCDC93

4.32e-0470211510C0009402
Diseaselong QT syndrome (implicated_via_orthology)

KCNH6 KCNH2

6.64e-04101152DOID:2843 (implicated_via_orthology)
DiseasePR interval

KIF13B LAMB2 LAMC1 NCKAP5 SYNE2 MACF1 CDC5L XPO7

7.32e-044951158EFO_0004462
DiseaseFanconi anemia

RAD51C FANCI

1.33e-03141152cv:C0015625
DiseaseMeckel-Gruber syndrome

CC2D2A CSPP1

1.53e-03151152C0265215
Diseasecaffeine measurement

LAMB2 LAMC1

1.53e-03151152EFO_0021177
DiseaseBone marrow hypocellularity

RAD51C FANCI

2.21e-03181152C1855710
DiseaseMeckel syndrome type 1

CC2D2A CSPP1

2.21e-03181152C3714506
DiseaseDiGeorge syndrome (implicated_via_orthology)

DOCK1 HOXA3

2.47e-03191152DOID:11198 (implicated_via_orthology)
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

EHBP1L1 SYNE2 NPC1L1 MACF1

2.47e-031441154EFO_0004611, EFO_0020943
Diseasealbumin:globulin ratio measurement

TNFSF13 FAM167A NAIF1

2.94e-03731153EFO_0005128
DiseaseMalignant neoplasm of breast

RAD51C NCOA3 KRT14 MCF2L2 HOXA3 UNC45B SYNE2 NLRC5 MACF1 CD74 HSD17B8

3.20e-03107411511C0006142
DiseasePrimary microcephaly

STIL PLK4

3.31e-03221152C0431350
Diseasealcohol consumption measurement

DOCK1 TNFSF13 FAM114A2 LGALS12 NCKAP5 SPTBN5 MMEL1 ABI2 RABGAP1L MAD1L1 HS6ST3 XPO7

3.35e-03124211512EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
LQLRTEVETQQVMRN

AZI2

136

Q9H6S1
QMVEILSDENRNLRQ

AMOT

436

Q4VCS5
RILQEAQNLMALTNV

CDC5L

361

Q99459
ILNLNNISSDRIQLM

BPIFB1

396

Q8TDL5
DIRQMSQQQDLLSAL

CATSPER4

436

Q7RTX7
NLTDSNLQNRIRDQM

CASS4

506

Q9NQ75
LQELSSNDMLLLQLR

ARL14EP

31

Q8N8R7
LLSQTQREQMSLLAA

CCDC171

716

Q6TFL3
LLQSLLNEMNTLRTQ

BEST1

206

O76090
SQLENRILNQTADML

ANGPTL2

156

Q9UKU9
RLSQLQSENMLLRQQ

CCDC144CP

851

Q8IYA2
RENSSNILDNLLSRM

NPR1

806

P16066
LSQLQSENMLLRQQL

ANKRD26

1136

Q9UPS8
NALNSLSENQSLLRM

ATP2A1

911

O14983
NVLQMLDIQASQLRR

ABI2

71

Q9NYB9
SLRTRLLNGLAQQMI

RAD51C

256

O43502
QMTIQALQDELRIQR

ERC1

226

Q8IUD2
RETLLRQLETNQLDM

RABL6

236

Q3YEC7
LLSQLNERQERIMNE

RABGEF1

416

Q9UJ41
QVLQMREGLQSLRQA

KCNH3

891

Q9ULD8
QIDRLDFIRNQMNLL

MFN1

376

Q8IWA4
RTLRNITNNADIQQM

PAXIP1

336

Q6ZW49
DVLRRNSQLANSVMQ

FANCI

611

Q9NVI1
NLQRAISRNLMQRAS

PSKH2

331

Q96QS6
QQSMQLEERAEQIRS

MAD1L1

46

Q9Y6D9
RVEMANLLNLTERQI

HOXA3

221

O43365
NEISEMNRAIQRLQA

KRT7

306

P08729
HLEQQNDLLQMIRRS

NAIF1

246

Q69YI7
NDLLQMIRRSQEVQA

NAIF1

251

Q69YI7
RTMQNLEIELQSQLS

KRT14

336

P02533
RMQAQQALLLESLRQ

FAM184B

721

Q9ULE4
RDSEQQMINIARQSL

HECTD2

386

Q5U5R9
QRQLNRLETRLSADM

KCNH2

1046

Q12809
LEQLQAQMNRLESRV

KCNH6

826

Q9H252
IQTLMLQNRTLLEQN

CCDC88A

1331

Q3V6T2
NLNQLENVTTMERLL

MCF2L2

281

Q86YR7
SMNQQALEQLRELRI

LGALS12

311

Q96DT0
NIRLDSVSLRMQQDL

COLEC12

391

Q5KU26
NLITDLNRMHRQNID

CSPP1

686

Q1MSJ5
QRLMSASNSNELLLN

ODAM

21

A1E959
NALIRRQDQLQLLME

EHBP1L1

1416

Q8N3D4
LEARMRSVLQAINLQ

LAMB2

1776

P55268
NNQMLSLLNRRQEER

GOLGA6L3

186

A6NEY3
NNQMLSLLNRRQEER

GOLGA6L4

186

A6NEF3
NNQMLSLLNRRQEER

GOLGA6L9

186

A6NEM1
NNQMLSLLNRRQEER

GOLGA6L10

186

A6NI86
NNQMLSLLNRRQEER

GOLGA6L19

186

H0YKK7
LERQLALMNSQFNRR

MMEL1

216

Q495T6
LLSSLEAQLMQIRSN

KRT20

331

P35900
NTFQELQVMRRSLNL

ITPRID2

956

P28290
ANNRQVRMLADLSLV

HS6ST1

246

O60243
ANNRQVRMLADLSLV

HS6ST3

306

Q8IZP7
IINENQRVSMSRNIE

IL17F

61

Q96PD4
QMTCLQSLRLNRNSI

NLRC5

1576

Q86WI3
QDLSPQQNRQMLRLL

MACF1

3561

Q9UPN3
MLRLLNELQRSFQDI

MACF1

3571

Q9UPN3
NRRLQEASMRLEQEN

RABGAP1L

16

B7ZAP0
NNRTLLLLTANQTLM

NPC1L1

496

Q9UHC9
SILQNLRALVAMNEN

CCDC93

381

Q567U6
ANSRSLSQILMEQLQ

ICE2

451

Q659A1
EVARTNQNIMENRLL

CC2D2A

321

Q9P2K1
RSNTSLLQQNLRQLM

DOCK1

626

Q14185
SEMQIQDQSLLLTLR

C20orf202

46

A1L168
MASQLQNRLRSALAL

HSD17B8

1

Q92506
MLSDLTLQLRQRQEN

ARFGEF3

166

Q5TH69
MARLTESEARRQQQQ

CELF5

1

Q8N6W0
SIRQQELSALRQDMQ

CEP250

1076

Q9BV73
NQLQMATSLDRLLSL

BPIFB6

371

Q8NFQ5
RTRLESLQGENQMLQ

BICDL2

196

A1A5D9
NQMLQSRRQDLEAQI

BICDL2

206

A1A5D9
LMNRNATLSQVLREA

FAM114A2

201

Q9NRY5
LQRNFQLMRELDQRT

ING5

21

Q8WYH8
DLLQLLESQMQERNN

CYBB

456

P04839
ANNRQVRMLSDLTLV

HS6ST2

386

Q96MM7
DQNLMDRLQRVNNTL

LAMC1

1096

P11047
NQRTIQNDIMLLQLS

CTSG

101

P08311
LQSLSQRLRVQEQEM

EML3

16

Q32P44
LQQQLQEVLGRSLSM

DCST2

681

Q5T1A1
LTVTSQNLQLENLRM

CD74

81

P04233
RLSQLQSENMLLRQQ

CCDC144A

1041

A2RUR9
TDNILTNNQTLRLLM

CERCAM

146

Q5T4B2
MVSLRELHLNNNLLR

CNOT6

96

Q9ULM6
SRQQLALNLLEMIQQ

FOCAD

376

Q5VW36
LQRNFQLMRDLDQRT

ING4

21

Q9UNL4
EQRSNLMNNILRIIS

RALGPS2

226

Q86X27
LMNNILRIISDLQQS

RALGPS2

231

Q86X27
ELTEMRLQDQQLARQ

FAM167A

126

Q96KS9
SQMLLSRRNQLLLEF

NIPSNAP1

156

Q9BPW8
EATLNNSLMRLREQI

KIF13B

676

Q9NQT8
QRLTNLRLQNMKSDT

SPEF2

121

Q9C093
RDMAQLRLQLEVSQL

SMG5

826

Q9UPR3
LQMQLNTSIDLRTNV

SYNE2

3236

Q8WXH0
EMQQLRSCNRQLQID

TAB2

591

Q9NYJ8
LLRLHLNSNRLQMIN

LRRN3

166

Q9H3W5
LESERNRIQMRSLQQ

NCKAP5

96

O14513
LNAQMVAQRSRELLS

NCOA3

1221

Q9Y6Q9
QALRLQLQQEMELLN

TAOK3

796

Q9H2K8
ANMNATIRRIDQLTN

SLC40A1

171

Q9NP59
LLQAQARERTLAMQA

TEX45

96

Q8NA69
DLTLSNLLLTRNMNI

PLK4

136

O00444
KENQMLRRLLSQSCQ

SPATC1L

26

Q9H0A9
QAMLQELLVSAQRLR

SPTBN5

2476

Q9NRC6
QLASARNRRLAQQME

CHTOP

46

Q9Y3Y2
EQLQRTQSQLLQMVL

CLEC4F

456

Q8N1N0
QNNTRLESRTQLVTM

SUPT6H

1006

Q7KZ85
MRLRLLNEECEQNLQ

TRIML2

111

Q8N7C3
QNFQEMLRRLNTSIQ

UNC45B

111

Q8IWX7
LQAQIQRLLEAQSLM

STIL

736

Q15468
TSELLRQLRQAMRNS

XPNPEP1

6

Q9NQW7
MIQRLQQEQDLRRSG

PHIP

646

Q8WWQ0
DLQLQLEQLRGRTTM

WDR97

981

A6NE52
RDIQQTLTQNMERIF

XPO5

176

Q9HAV4
SELSRMSAAQRQQLL

SLX9

176

Q9NSI2
TMDNRLTIQANLNRL

GTF3C4

186

Q9UKN8
DMLRENRSLQSLNIE

TMOD4

246

Q9NZQ9
LVLNRNLSISENRTM

RET

356

P07949
RISMQNLEALLVANR

TSGA10

561

Q9BZW7
SRIRNELMQSLNQDS

TRIP11

621

Q15643
RVLQLMNLTDSRLAQ

XPO7

526

Q9UIA9
RSQNSMNRLAVQALE

ZNRF3

246

Q9ULT6
LLLAQNREQQEELMR

SNAPC4

106

Q5SXM2
ADRVIQRTNSMQQLE

PLEKHA5

401

Q9HAU0
MALLTQQTELQSLRR

TNFSF13

46

O75888
LNLAEMLSLREQQLQ

TPRX2

51

P0DV77
MNIQLVTSQIDAQRR

ALYREF

176

Q86V81
QQLMLRLSENREQLE

VPS13D

4371

Q5THJ4