Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.87e-08111705GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.93e-08141705GO:0003964
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

6.51e-07371706GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

7.68e-07381706GO:0070001
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.68e-07211705GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.47e-05371705GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.69e-05381705GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.36e-05461705GO:0016893
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7L AKR7A3

2.15e-0431702GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7L AKR7A3

2.15e-0431702GO:0019118
GeneOntologyMolecularFunctionisomerase activity

GPI SRR TOP6BL ITPK1 GSTA3 FBH1 PDILT HSD17B4

2.45e-041921708GO:0016853
GeneOntologyMolecularFunctionMHC protein complex binding

HLA-DRB1 HLA-DRB3 HLA-DRB4 CD160

4.02e-04411704GO:0023023
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

5.72e-04791705GO:0004521
GeneOntologyMolecularFunctioncalcium ion binding

FAT4 PGS1 EFCAB6 ITLN1 CDHR3 SRR PPEF2 LRP1B PCDH17 ITPR1 MYL12A CELSR1 MEGF8 PLA2G4B C1R PCDH9

6.84e-0474917016GO:0005509
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11 CNOT1

1.10e-031361706GO:0004540
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.12e-08131685GO:0015074
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB3 HLA-DRB4

3.35e-0581603PD000328
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.99e-0591603IPR000353
DomainMHC_II_beta

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.99e-0591603SM00921
DomainMHC_II_beta

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.99e-0591603PF00969
DomainIPT

EBF3 PKHD1L1 PKHD1 PLXNB3

7.81e-05271604SM00429
DomainTIG

EBF3 PKHD1L1 PKHD1 PLXNB3

1.36e-04311604PF01833
DomainIPT

EBF3 PKHD1L1 PKHD1 PLXNB3

1.55e-04321604IPR002909
DomainARM-type_fold

RELCH VPS11 NBEAL1 PSMD1 COPG2 ITPR1 AP4E1 CSE1L PIK3CB VPS35 AP1G2

1.68e-0433916011IPR016024
DomainMHC_II_a/b_N

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.10e-04141603IPR014745
Domain-

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.10e-041416033.10.320.10
DomainEF-hand_11

EFCAB6 MYL12A

2.18e-0431602PF08976
DomainEF_hand_DJBP

EFCAB6 MYL12A

2.18e-0431602IPR015070
DomainClathrin/coatomer_adapt-like_N

COPG2 AP4E1 AP1G2

2.60e-04151603IPR002553
DomainAdaptin_N

COPG2 AP4E1 AP1G2

2.60e-04151603PF01602
DomainIg_E-set

EBF3 PKHD1L1 TGM4 A2ML1 PKHD1 PLXNB3

2.73e-041041606IPR014756
DomainG8_domain

PKHD1L1 PKHD1

4.33e-0441602IPR019316
DomainG8

PKHD1L1 PKHD1

4.33e-0441602PS51484
DomainG8

PKHD1L1 PKHD1

4.33e-0441602SM01225
DomainG8

PKHD1L1 PKHD1

4.33e-0441602PF10162
DomainCadherin

FAT4 CDHR3 PCDH17 KIAA0319 CELSR1 PCDH9

5.38e-041181606IPR002126
DomainGST_alpha

GSTA3 GSTA4

7.17e-0451602IPR003080
DomainGST_N

GSTA3 GSTA4 VARS1

8.43e-04221603PF02798
DomainTPR

APPBP2 TTC28 BBS4 TTC7B TTC23 CTR9

8.60e-041291606SM00028
DomainTPR_2

TTC28 BBS4 TTC7B CTR9

8.79e-04501604PF07719
DomainTPR_2

TTC28 BBS4 TTC7B CTR9

8.79e-04501604IPR013105
DomainEGF

FAT4 LRP1B PTGS2 MEP1B CELSR1 MEGF8 BRINP2 C1R

9.66e-042351608SM00181
DomainTPR_repeat

APPBP2 TTC28 BBS4 TTC7B TTC23 CTR9

1.01e-031331606IPR019734
DomainPbH1

PKHD1L1 PKHD1

1.07e-0361602SM00710
DomainMANSC

KIAA0319L KIAA0319

1.07e-0361602PS50986
DomainMANSC_dom

KIAA0319L KIAA0319

1.07e-0361602IPR013980
DomainPKD/REJ-like

KIAA0319L KIAA0319

1.07e-0361602IPR002859
DomainREJ

KIAA0319L KIAA0319

1.07e-0361602PF02010
DomainPbH1

PKHD1L1 PKHD1

1.07e-0361602IPR006626
DomainTPR_8

TTC28 BBS4 TTC7B CTR9

1.10e-03531604PF13181
DomainGST_C

GSTA3 GSTA4 VARS1

1.39e-03261603IPR004046
DomainGST_C

GSTA3 GSTA4 VARS1

1.39e-03261603PF00043
PathwayWP_EICOSANOID_LIPID_SYNTHESIS_MAP

PGS1 PTGS2 PLA2G4B

7.62e-05101243MM15916
PathwayBIOCARTA_BBCELL_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.04e-04111243M22030
PathwayBIOCARTA_EOSINOPHILS_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.04e-04111243M22048
PathwayBIOCARTA_IL5_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.78e-04131243M18928
PathwayBIOCARTA_MHC_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.25e-04141243M22023
PathwayBIOCARTA_BLYMPHOCYTE_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.25e-04141243M1473
PathwayBIOCARTA_TCRA_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.25e-04141243M10765
PathwayBIOCARTA_ASBCELL_PATHWAY

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.80e-04151243M7298
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.80e-04151243M47588
PathwayKEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.80e-04151243M47604
Pubmed

HLA-DR genotypes influence age at disease onset in children and juveniles with type 1 diabetes mellitus.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.17e-073171320371654
Pubmed

Association of HLA-DR3 and HLA-DR4 with sinonasal polyposis in Mexican Mestizos.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.17e-073171316815190
Pubmed

Binding domain regulation of MHC class II molecule assembly, trafficking, fate, and function.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.17e-07317138775462
Pubmed

A male-specific increase in the HLA-DRB4 (DR53) frequency in high-risk and relapsed childhood ALL.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.17e-073171312008082
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PGS1 MAN2B1 TTC28 RPS6KA1 ERGIC2 MADD ITPR1 RINT1 TSR1 CTR9 ASB3 AFDN EIF2AK4 ARHGEF2 HSD17B4 EXOC4

1.57e-076501711638777146
Pubmed

Intracellular overexpression of HIV-1 Nef impairs differentiation and maturation of monocytic precursors towards dendritic cells.

HLA-DRB1 HLA-DRB3 HLA-DRB4 ITGAX

1.81e-0711171422808111
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RELCH CENPC PSMD1 COPG2 RB1CC1 PPEF2 MADD ITPR1 CACTIN RINT1 CSE1L TTC7B TSR1 CTR9 KLHL15 EIF2AK4 ARHGEF2 HSD17B4 CNOT1 ATP2B4

2.60e-0710491712027880917
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TTC28 VPS45 HLA-DRB1 KIAA0319L ZMYND8 APBA2 ZNF521 PSMD1 LRP1B GFPT1 MADD CCDC13 FBH1 TTC7B CTR9 ASB3 AFDN HSD17B4 CADPS2 VARS1 PLXNB3 EXOC4

3.92e-0712851712235914814
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ABCB7 SMC6 BBS4 PSMD1 COPG2 PTGS2 CD160 MADD ITPR1 TGM4 GRAMD2A ORC4 TSR1 MTHFD1 CTR9 CRYBG1 EIF2AK4 MPHOSPH10 CNOT1 FAM135A

4.36e-0710841712011544199
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25 ERVK-11

4.39e-0794171721542922
Pubmed

Allelic variation in the DR subregion of the human major histocompatibility complex.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-07417133476943
Pubmed

HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171314677183
Pubmed

Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171319922436
Pubmed

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171326740600
Pubmed

Association of HLA-DR and -DQ genes with narcolepsy in Koreans: comparison with two control groups, randomly selected subjects and DRB1*1501-DQB1*0602--positive subjects.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171317002906
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

4.65e-074171310469592
Pubmed

HLA-DRB alleles and systemic lupus erythematosus in Jamaicans.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171312144077
Pubmed

Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171318520346
Pubmed

HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasis.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.65e-074171315795121
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

CUL4A HAUS6 ABCB7 ZMYND8 PSMD1 COPG2 COG8 CSE1L CTR9 VPS35 AFDN CNOT1 VARS1 EXOC4

8.07e-075601711435241646
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-18

1.16e-065171312629516
Pubmed

Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171317910142
Pubmed

Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171316973583
Pubmed

Genetic variability in HIV-1 gp120 affects interactions with HLA molecules and T cell receptor.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-06517131970352
Pubmed

Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-06517137645219
Pubmed

A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171312392858
Pubmed

Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171315908298
Pubmed

HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171312209103
Pubmed

Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.

GSTA3 GSTA4 NR5A1

1.16e-065171323650189
Pubmed

HLA-DQA is associated with abdominal aortic aneurysms in the Belgian population.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171317182961
Pubmed

HLA-DRB4 as a genetic risk factor for Churg-Strauss syndrome.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171317763415
Pubmed

NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171311782380
Pubmed

Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171323152536
Pubmed

HLA-DR-restricted peptides identified in the Nef protein can induce HIV type 1-specific IL-2/IFN-gamma-secreting CD4+ and CD4+ /CD8+ T cells in humans after lipopeptide vaccination.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171317411376
Pubmed

Productive human immunodeficiency virus type 1 assembly takes place at the plasma membrane.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171317507489
Pubmed

Competition of HLA-DR and a beta 2 domain peptide for HIV envelope glycoprotein gp120 binding to CD4.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-06517137734415
Pubmed

Visual hallucinations and HLA class II antigens in cortical dementia.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171320606439
Pubmed

HLA-DR and DQB1 gene polymorphism in the North-western Colombian population.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171312144632
Pubmed

HIV-1 gag polyprotein rescues HLA-DR intracellular transport in a human CD4+ cell line.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.16e-065171312202216
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-10 ERVK-18 ERVK-25 ERVK-11

1.64e-0618171418664271
Pubmed

Frequency of concurrent autoimmune disorders in patients with autoimmune hepatitis: effect of age, gender, and genetic background.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171318223493
Pubmed

Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171319233472
Pubmed

Association of immune responses to mycobacterium tuberculosis peptide antigens with host genetic factors.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171317153701
Pubmed

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171318305173
Pubmed

HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcoma.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171315902698
Pubmed

Sequence analysis of HLA class II genes from insulin-dependent diabetic individuals.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-06617133372263
Pubmed

HLA risk markers for chronic myelogenous leukemia in Eastern Canada.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171319235017
Pubmed

A comparison of molecular HLA-DR and DQ allele profiles forming DR51-, DR52-, and DR53-related haplotypes in five ethnic Thai populations from mainland southeast Asia.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171311082517
Pubmed

Complete coding sequences and haplotypic associations of HLA-B*0707, -B*1524, -B*4405, -B*4802, -DRB1*0409, -DRB1*0411, -DRB1*1115, -DRB1*1305, and the novel allele -DRB1*0709. Group-specific amplification of cDNA from DRB1 alleles associated to DRB3 and DRB4.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171315896200
Pubmed

HLA class II DNA typing in a large series of European patients with systemic lupus erythematosus: correlations with clinical and autoantibody subsets.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171311997714
Pubmed

HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites.

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.31e-066171314508706
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

GPI ZNF780B PSMD1 COPG2 GFPT1 CSE1L TSR1 MTHFD1 VPS35 PAX9 DHTKD1 KLB

2.68e-064511711236168627
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 APPBP2 CDKL2 MUC19 GFPT1 DNAH14 USP20 PCDH17 MYL12A MTHFD1 TLN1 PKHD1 TUBE1 CNOT1 PLXNB3

4.00e-067361711529676528
Pubmed

Anti-cofactor autoantibodies in systemic lupus erythematosus: prevalence, clinical and HLA class II associations.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.03e-067171318569076
Pubmed

The HIV core protein p24 inhibits interferon-gamma-induced increase of HLA-DR and cytochrome b heavy chain mRNA levels in the human monocyte-like cell line THP1.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.03e-06717131905983
Pubmed

Human macrophages accumulate HIV-1 particles in MHC II compartments.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.03e-067171312230470
Pubmed

[Human leukocyte antigen genes to genetic predisposition in diffuse panbronchiolitis].

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.03e-067171318846964
Pubmed

The impact of anti-HY responses on outcome in current and subsequent pregnancies of patients with recurrent pregnancy losses.

HLA-DRB1 HLA-DRB3 HLA-DRB4

4.03e-067171320307907
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

HAUS6 ABCB7 TTC28 VPS45 KIAA0319L LRP1B GFPT1 AP4E1 RINT1 TSR1 TLN1 AFDN ARHGEF2 HSD17B4 CNOT1 EXOC4

5.39e-068531711628718761
Pubmed

Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy.

HLA-DRB1 HLA-DRB3 HLA-DRB4

6.42e-068171319223392
Pubmed

Correlation between HLA and pityriasis rosea susceptibility in Brazilian blacks.

HLA-DRB1 HLA-DRB3 HLA-DRB4

6.42e-068171316405603
Pubmed

HLA-A, B, Cw, DRB1, DRB3/4/5, DQB1 in German patients suffering from rapidly progressive periodontitis (RPP) and adult periodontitis (AP).

HLA-DRB1 HLA-DRB3 HLA-DRB4

6.42e-068171312296785
Pubmed

Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort.

HLA-DRB1 HLA-DRB3 HLA-DRB4

6.42e-068171317106278
Pubmed

Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation.

HLA-DRB1 HLA-DRB3 HLA-DRB4

6.42e-068171323729440
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GPI FAT4 HAUS6 EFCAB6 TTC28 VPS45 SMC6 KIAA0319L COPG2 PKHD1L1 AP4E1 MTHFD1 AFDN FAM135A PCDH9

7.64e-067771711535844135
Pubmed

The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs.

CUL4A PSMD1 PTGS2

9.60e-069171317429597
Pubmed

Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses.

HLA-DRB1 HLA-DRB3 HLA-DRB4

9.60e-069171324505475
Pubmed

Major histocompatibility complex class-II molecules promote targeting of human immunodeficiency virus type 1 virions in late endosomes by enhancing internalization of nascent particles from the plasma membrane.

HLA-DRB1 HLA-DRB3 HLA-DRB4

9.60e-069171323170932
Pubmed

Differential effects of R5 and X4 human immunodeficiency virus type 1 infection on CD4+ cell proliferation and activation.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.37e-0510171315784911
Pubmed

Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.37e-0510171312956878
Pubmed

HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.37e-051017138450224
Pubmed

Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART.

HLA-DRB1 HLA-DRB3 HLA-DRB4

1.87e-0511171321085635
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

HAUS6 TTC28 VPS45 RB1CC1 RINT1 EIF2AK4 HSD17B4 ATP2B4

1.97e-05230171835449600
Pubmed

Two distinct subtypes of the HLA-DRw12 haplotypes in the Japanese population detected by nucleotide sequence analysis and oligonucleotide genotyping.

HLA-DRB1 HLA-DRB4

2.40e-05217122592019
Pubmed

CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23.

ITGAX IL23A

2.40e-052171226242598
Pubmed

Paediatric celiac patients carrying the HLA-DR7-DQ2 and HLA-DR3-DQ2 haplotypes display small clinical differences.

HLA-DRB1 HLA-DRB3

2.40e-052171224628273
Pubmed

Exome sequencing of child-parent trios with bladder exstrophy: Findings in 26 children.

TSPAN4 TUBE1

2.40e-052171234355505
Pubmed

Structural comparison of the genes of two HLA-DR supertypic groups: the loci encoding DRw52 and DRw53 are not truly allelic.

HLA-DRB1 HLA-DRB4

2.40e-05217123596674
Pubmed

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

HLA-DRB1 HLA-DRB3

2.40e-05217126589154
Pubmed

Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.

GSTA3 GSTA4

2.40e-05217129480897
Pubmed

DRB1*03 diversity and DRB3 associations in five major population groups in the United States.

HLA-DRB1 HLA-DRB3

2.40e-052171211872240
Pubmed

The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice.

ABCB7 CD79A

2.40e-052171234762046
Pubmed

Structural organization of the DR subregion of the human major histocompatibility complex.

HLA-DRB1 HLA-DRB4

2.40e-05217123860851
Pubmed

A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR beta ser 57- asp 57).

HLA-DRB1 HLA-DRB3

2.40e-05217122497068
Pubmed

HLA-DR4 as a risk allele for autism acting in mothers of probands possibly during pregnancy.

HLA-DRB1 HLA-DRB4

2.40e-052171219487610
Pubmed

HLA-DR association in papillary thyroid carcinoma.

HLA-DRB1 HLA-DRB4

2.40e-052171220164547
Pubmed

The conundrum of HLA-DRB1*14:01/*14:54 and HLA-DRB3*02:01/*02:02 mismatches in unrelated hematopoietic SCT.

HLA-DRB1 HLA-DRB3

2.40e-052171220972469
Pubmed

Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis.

GHRL ABCB4

2.40e-052171232994489
Pubmed

Identification of a novel HLA-DRB1 allele (HLA-DRB1*111902*).

HLA-DRB1 HLA-DRB4

2.40e-052171215982264
Pubmed

Development of a new HLA-DRB real-time PCR typing method.

HLA-DRB1 HLA-DRB3

2.40e-052171215620466
Pubmed

Sequence and evolution of HLA-DR7- and -DRw53-associated beta-chain genes.

HLA-DRB3 HLA-DRB4

2.40e-05217123110774
Pubmed

Difference in pathogenesis between vitiligo vulgaris and halo nevi associated with vitiligo is supported by an HLA association study.

HLA-DRB1 HLA-DRB4

2.40e-052171215140072
Pubmed

Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.

HLA-DRB1 HLA-DRB3

2.40e-052171216320316
Pubmed

Description of two new HLA-DRB alleles (DRB1*0310 and DRB3*01012) found in a Spanish infant.

HLA-DRB1 HLA-DRB3

2.40e-05217129234492
Pubmed

T cell receptors recognizing type II collagen in HLA-DR-transgenic mice characterized by highly restricted V beta usage.

HLA-DRB1 HLA-DRB4

2.40e-052171215188377
Pubmed

Tracking antigen-specific T-cells during clinical tolerance induction in humans.

HLA-DRB1 HLA-DRB3

2.40e-052171220543955
Pubmed

Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis.

HLA-DRB1 HLA-DRB3

2.40e-052171216200610
Pubmed

HLA-DRB1*15:01 and HLA-DRB3*02:02 in PLA2R-Related Membranous Nephropathy.

HLA-DRB1 HLA-DRB3

2.40e-052171228028136
Pubmed

HLA-DRB1 and -DRB3 allele frequencies and haplotypic associations in Koreans.

HLA-DRB1 HLA-DRB3

2.40e-052171215041167
Pubmed

The unusual DRB1*08:01 haplotype carrying DRB3*02:02 confirmed in a Dutch family.

HLA-DRB1 HLA-DRB3

2.40e-052171223742216
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC28 BBS4 TTC7B TTC23 CTR9

6.59e-041151095769
GeneFamilyATP binding cassette subfamily B

ABCB7 ABCB4

1.91e-03111092806
GeneFamilyC1-set domain containing

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.06e-03421093591
GeneFamilyNon-clustered protocadherins

PCDH17 PCDH9

2.28e-0312109221
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.36e-03441093588
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 KCTD19 MYO7B MUC19 LRP1B PKHD1L1 ADCY8 PKHD1

1.33e-071601628c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 KCTD19 MYO7B MUC19 LRP1B PKHD1L1 ADCY8 PKHD1

1.33e-07160162825c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPY19L3 ZNF521 CCDC168 ADCY8 DNAH14 KIAA0319 CFAP221 CADPS2

2.53e-071741628ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL11A1 ITPK1 KIAA0319 CFAP221 SLC22A10 C1R VAV3 CADPS2

3.42e-0718116286e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL11A1 EFCAB6 MYO7B MDGA2 LRP1B PKHD1L1 PKHD1

3.88e-0718416282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL11A1 EFCAB6 MYO7B MDGA2 LRP1B PKHD1L1 PKHD1

3.88e-0718416282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL11A1 EFCAB6 MYO7B MDGA2 LRP1B PKHD1L1 PKHD1

3.88e-071841628ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

NBEAL1 CPM DNAH14 ST6GALNAC5 PKHD1 AFDN ARHGEF2 CADPS2

5.15e-071911628d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL11A1 CDKL2 CPM ADCY8 DNAH14 CFAP221 PKHD1 CADPS2

5.35e-071921628fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellNeuronal-Excitatory-eC(RORB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPY19L3 COL11A1 CCDC168 ITPK1 KIAA0319 CFAP221 C1R CADPS2

7.29e-0720016288c803a0ce25e140b46036f6aabefc5502601f408
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 MDGA2 TOP6BL LRP1B PDILT PKHD1 C2CD6

1.05e-06145162796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL11A1 MDGA2 TOP6BL LRP1B PKHD1L1 PDILT PKHD1

2.20e-061621627bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'_v3-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

MYO7B HLA-DRB1 PKHD1L1 ITPR1 ABCB4 CD79A PCDH9

3.27e-061721627f16f90d17feac1ee52fd513907b28456865fd31d
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

GHRL KCTD19 SMC6 EIF2AK4 DHTKD1 PCDH9 MCOLN2

4.58e-061811627277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

GHRL KCTD19 SMC6 EIF2AK4 DHTKD1 PCDH9 MCOLN2

4.58e-0618116272caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell3'_v3-blood-Lymphocytic_B|blood / Manually curated celltypes from each tissue

MYO7B HLA-DRB1 PKHD1L1 ITPR1 ABCB4 CD79A PCDH9

5.47e-0618616275624b1fc7eab9f505588fcc86a24d14f8bcbfef7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDKL2 CPM GSTA4 CFAP221 PKHD1 ARHGEF2 HSD17B4

5.67e-0618716275df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

HLA-DRB1 SMC6 ITPR1 ABCB4 CELSR1 CD79A PCDH9

6.29e-06190162740b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

HLA-DRB1 SMC6 ITPR1 ABCB4 CELSR1 CD79A PCDH9

6.29e-061901627a37a32dc1b931562a6660074e19d5598efc65284
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPM LRP1B INPP4B ITPR1 CFAP221 ST6GALNAC5 PCDH9

6.29e-061901627cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

HLA-DRB1 HGSNAT CPM CRYBG1 EIF2AK4 PRKAG2 MCOLN2

6.51e-0619116272af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL11A1 CDKL2 DNAH14 GSTA4 CFAP221 CADPS2 PCDH9

6.74e-061921627cc9911e182a289779a2612bc213daae5607689e7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GHRL MAN2B1 ZNF549 CPM ABCB4 PLA2G4B TSPAN4

7.21e-061941627b829a63b51b92507a53ffd0393bd9458b2b9440f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL CPM DNAH14 CELSR1 PKHD1 AFDN FAM135A

7.21e-0619416277002937e8903e037332a215d00fbc7c7843b33f2
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

APBA2 IFI16 ITGAX CD160 MYL12A CRYBG1 VAV3

7.71e-0619616278a3a63129adfbe58558af91336f81d397c291ed0
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DRB1 SMC6 NT5C3B CPM ITGAX CD79A PCDH9

8.24e-061981627dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPM PXDN TLN1 PKHD1 TSPAN4 C1R AFDN

8.51e-061991627174f6013af6eafa577f84205a62927f2b367fda3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPI ITGAX ITPR1 TLN1 SLC22A10 VAV3 PRKAG2

8.51e-061991627379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DRB1 SMC6 ITPR1 ABCB4 CD79A VAV3 PCDH9

8.79e-062001627222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAXDC2 ITGAX CD160 GSTA4 ST6GALNAC5 PCDH9

1.59e-051461626447c05414eda71681a0c07baba900f88ed6165ed
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7B HLA-DRB1 ITPR1 ABCB4 CD79A PCDH9

1.92e-0515116260f8f07e44c6edaf09574930b416fdce14d67095a
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

CDKN3 PGS1 CDKL2 ZNF549 GFPT1 AP4E1

2.15e-051541626a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL BEND2 LRP1B CRYBG1 PRKAG2 CADPS2

2.57e-05159162650d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RPS6KA1 SH2D3C CCDC168 BEND2 IL23A VAV3

2.57e-0515916260a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RPS6KA1 SH2D3C CCDC168 BEND2 IL23A VAV3

2.57e-051591626299e2162a82e31196d7f3a110c2db622349edfff
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TP53I3 CPM DNAH14 GSTA4 CFAP221 PKHD1

2.57e-051591626e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MDGA2 CCDC168 PTGS2 BRINP2 C1R LSM4

3.17e-051651626cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DRB1 ITPR1 ABCB4 CELSR1 CD79A PCDH9

3.17e-051651626fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

KCTD19 SH2D3C LRP1B PCDH17 PXDN SLC22A10

3.39e-0516716265af9127bae05768a5164d5708a4ad37edca99324
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELCH HAUS6 CCDC168 INPP4B TUBE1 EXOC4

3.50e-051681626a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDKN3 EBF3 IL23A GSTA4 PAX9 CDC20

3.50e-051681626f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 CPM LRP1B TTC7B VWA5A VAV3

3.62e-051691626fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 PKHD1L1 PXDN CD79A ALDOB

3.62e-051691626e3ec9468141b6456398dca17dd8eeaabd2462710
ToppCellURO-Lymphocyte-B-B_intermediate|URO / Disease, Lineage and Cell Type

SMC6 PKHD1L1 ABCB4 KIAA0319 CELSR1 CD79A

3.74e-051701626e11d1510518cedabeece96d4adbb90999e6326fa
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 CPM LRP1B TTC7B VWA5A VAV3

3.74e-051701626c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_naive|bone_marrow / Manually curated celltypes from each tissue

MYO7B HLA-DRB1 ABCB4 TTC23 CD79A PCDH9

3.87e-051711626fcc31a9a69f96de10d1324a5a4fbfe4289bf4984
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 SMC6 NT5C3B CD79A PCDH9 MCOLN2

3.87e-051711626a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN3 RELCH COPG2 COG8 AP1G2 CDC20

4.00e-051721626ebeda7ef181cac0109be750a98e7589c615d2724
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL11A1 LRP1B DNAH14 ITPK1 C1R VAV3

4.13e-0517316264ec147479b359cce1975d57a50ee1437a0e1e663
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NBEAL1 TRPC4 MDGA2 CPM INPP4B PCDH9

4.26e-0517416268393f0b43c767839c1630bcb952d62b42efc788d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGS1 MDGA2 ADCY8 COG8 RRN3 PCDH9

4.40e-051751626dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 MUC19 LRP1B ADCY8 PKHD1 CD79A

4.40e-051751626887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DRB1 SMC6 ITPR1 ABCB4 CD79A PCDH9

4.54e-051761626ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF521 CCDC168 ADCY8 DNAH14 VAV3 CADPS2

4.54e-05176162640993c41c1017b53039a337174fc56632b278609
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DRB1 SMC6 NT5C3B ITGAX TLN1 C2CD6

4.84e-051781626b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPY19L3 COL11A1 INPP4B KIAA0319 CFAP221 SLC22A10

4.84e-051781626f7f88879a05b2b5fa92cf5317b76f7a3064d1358
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D3C NDUFA7 PKHD1L1 PTGS2 CELSR1 TSPAN4

4.84e-0517816264b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

SH2D3C LRP1B PCDH17 PXDN VAV3 ATP2B4

5.15e-051801626b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 MUC19 LRP1B GSTA3 GSTA4 ALDOB

5.15e-05180162672310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MUC19 LRP1B DNAH14 PCDH17 PXDN ATP2B4

5.31e-0518116269de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 ADCY8 PXDN CFAP221 PKHD1 VAV3

5.31e-0518116269d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBA2 MDGA2 CPM CCDC13 PCDH9 PLXNB3

5.47e-051821626e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBA2 MDGA2 CPM CCDC13 PCDH9 PLXNB3

5.47e-051821626d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDKL2 CPM ADCY8 GSTA4 CFAP221 CADPS2

5.64e-0518316266847c1252d6bb105524f812658112517fd351eab
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL11A1 KIAA0319 CFAP221 SLC22A10 C1R CADPS2

5.64e-051831626b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 IFI16 PKHD1L1 CD79A PCDH9

5.64e-051831626f4f453692da77cef666cc281c4883c9c6b279fd4
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 IFI16 PKHD1L1 CD79A PCDH9

5.64e-0518316266086a862ab35bc683af44c03ee14cbb08ab99945
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPI LRP1B INPP4B ITPR1 ST6GALNAC5 PCDH9

5.81e-051841626e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ARHGAP40 GSTA3 GSTA4 CFAP221 CADPS2 PCDH9

5.99e-051851626673f0c688ae6984bc8027df2da335787924f4137
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-Naive_B_cells|GI_large-bowel / Manually curated celltypes from each tissue

HLA-DRB1 ITPR1 ABCB4 CELSR1 CD79A PCDH9

5.99e-0518516261c99373c123b5e0de40b47d9d885974a747b9839
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS11 HAUS6 SH2D3C ITGAX CD160 TUBE1

5.99e-051851626969248b63d4ce335f223528de756bcddffadbd77
ToppCellIIF-Lymphocyte-B-B_naive|IIF / Disease, Lineage and Cell Type

HLA-DRB1 PKHD1L1 ITPR1 ABCB4 CD79A PCDH9

5.99e-051851626dec48908addfc71f32f5ce0ce73f2926e476f60b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPM DNAH14 CELSR1 CFAP221 CADPS2 PCDH9

6.17e-0518616262ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell(1)_B_CD27neg|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MYO7B HLA-DRB1 PKHD1L1 ABCB4 CD79A PCDH9

6.17e-051861626646389147189760e9493c4f50f9583959ef0ee26
ToppCellBLOOD--(2)_Naive_B_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CD79A PCDH9

6.17e-0518616262e55a3892459152fc4a3a7834ccbf5d71b65d29a
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 MDGA2 LRP1B PTGS2 TLN1 PKHD1

6.17e-05186162623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDKL2 DNAH14 CFAP221 CADPS2 FAM135A PCDH9

6.17e-051861626acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellBLOOD--(2)_B_cell| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CD79A PCDH9

6.17e-051861626d9f2cab7f9e7aa476d9bcf5d15896113e59e03f8
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ARHGAP40 CPM GSTA4 CELSR1 CADPS2 PCDH9

6.36e-05187162681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPI LRP1B INPP4B ITPR1 CFAP221 PCDH9

6.36e-0518716267ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCelllymphoid-B_cell-Naive_B_cell|World / Lineage, cell class and subclass

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CD79A PCDH9

6.36e-051871626904ffd8cf4513e86fcd4c2b7faf24a34fbd2dce3
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

GHRL KCTD19 SMC6 DHTKD1 PCDH9 MCOLN2

6.36e-05187162699c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCelllymphoid-B_cell|World / Lineage, cell class and subclass

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CD79A PCDH9

6.36e-0518716262abbc01fd7f5b4e52113699625287893c991f8da
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 ITPR1 ABCB4 CD79A PCDH9

6.55e-051881626ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CELSR1 CD79A

6.55e-0518816265707786cc4452dc34f95db2b3cd29f6e025c0622
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-naive_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYO7B HLA-DRB1 SMC6 ABCB4 CD79A MCOLN2

6.55e-05188162631129152386e9aba16f749d78da12a08b916e6f8
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TOP6BL LRP1B CFAP221 PKHD1 CRYBG1 PRKAG2

6.55e-0518816268f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL LRP1B CRYBG1 PRKAG2 CADPS2 PCDH9

6.55e-0518816264154f4787483c7e076e87a187733a9f666742c3d
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7B HLA-DRB1 ITPR1 ABCB4 CD79A PCDH9

6.74e-051891626e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ZMYND8 PKHD1 VAV3 CADPS2 PCDH9 EXOC4

6.74e-051891626830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellMultiple_Sclerosis-Lymphocyte-B|Multiple_Sclerosis / Disease, Lineage and Cell Type

HLA-DRB1 SMC6 PKHD1L1 ABCB4 CD79A PCDH9

6.74e-051891626864f666b1e8557a689320075036920e3ac589b8b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS11 HLA-DRB1 SMC6 ITGAX CD79A MCOLN2

6.94e-051901626ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

MYO7B HLA-DRB1 PKHD1L1 ABCB4 CD79A PCDH9

6.94e-0519016263d45d5011305f13634013d9eeb98f235517dd54e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL11A1 KCTD19 CPM ADCY8 PKHD1 VAV3

6.94e-051901626625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 IFI16 ABCB4 CD79A PCDH9

6.94e-051901626e63945fa1dcd58bee129f1dd0c23b64a76241554
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 ITPR1 ABCB4 CD79A VAV3 PCDH9

6.94e-0519016260724665ac8238f2383c3a929d89abf4a48ec2420
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DRB1 SMC6 IFI16 ABCB4 CD79A PCDH9

6.94e-051901626fa65bc5a178ae0c80a9bd4b282e4539493128a64
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 SMC6 ITPR1 ABCB4 CD79A PCDH9

6.94e-051901626112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7B HLA-DRB1 ITPR1 ABCB4 CD79A PCDH9

6.94e-051901626a7498fe55b7810c482291db782dc5282675d246a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPI LRP1B INPP4B ITPR1 CFAP221 PCDH9

6.94e-0519016263dcadabbefe0128a5f30ab51234f049ab4d870c6
Diseaseaspirin-induced respiratory disease (is_implicated_in)

HLA-DRB1 HLA-DRB3 HLA-DRB4

2.50e-05111603DOID:0080822 (is_implicated_in)
DiseaseTinnitus

COL11A1 RB1CC1 ITGAX ITPK1 TGM4 PKHD1

7.93e-051301606HP_0000360
Diseaseliver cirrhosis (is_implicated_in)

CENPC HLA-DRB1 PTGS2 ABCB4

8.71e-05431604DOID:5082 (is_implicated_in)
Diseaseurate measurement

HLA-DRB1 TOP6BL CPT1A INPP4B CD160 AP4E1 ORC4 PDILT PKHD1 LSM4 NR5A1 PRKAG2 VARS1 KLB

3.89e-0489516014EFO_0004531
Diseaseimpulse control disorder

OMA1 PRKAG2

4.32e-0461602MONDO_0001162
DiseaseCREST Syndrome

HLA-DRB1 KIAA0319L

4.32e-0461602C0206138
Diseaseglomerular filtration rate, creatine measurement

PDILT PRKAG2

4.32e-0461602EFO_0005208, EFO_0010472
Diseaseextranodal nasal NK/T cell lymphoma

HLA-DRB1 HLA-DRB3

4.32e-0461602MONDO_0019472
DiseaseScleroderma, Limited

HLA-DRB1 KIAA0319L

4.32e-0461602C0748540
Diseasemagnesium measurement

TTC28 CDKL2 CCDC168 ADCY8

4.62e-04661604EFO_0004845
Diseaseuric acid measurement

FAT4 VPS45 TOP6BL CD160 ITPK1 KIAA0319 ORC4 SLC22A10 LSM4 PRKAG2 KLB

5.22e-0461016011EFO_0004761
DiseaseLupus Erythematosus, Systemic

HLA-DRB1 KIAA0319L PTGS2 C1R

6.10e-04711604C0024141
Diseasecesarean section, Self-injurious behavior

OMA1 CELSR1 EXOC4

6.91e-04321603EFO_0009636, HP_0100716
Diseaseinterleukin-21 measurement

HLA-DRB1 C1R

8.01e-0481602EFO_0801724
Diseasemorbid obesity (is_implicated_in)

GHRL BBS4

8.01e-0481602DOID:11981 (is_implicated_in)
Diseaseleptin measurement

ARHGAP40 HLA-DRB1 RB1CC1 LRP1B

1.00e-03811604EFO_0005000
Diseaseidiopathic pulmonary fibrosis (is_implicated_in)

HLA-DRB1 PTGS2

1.03e-0391602DOID:0050156 (is_implicated_in)
Diseaseheart disease (implicated_via_orthology)

GPI PIK3CB CNOT1

1.15e-03381603DOID:114 (implicated_via_orthology)
Disease3-methyl-2-oxobutyrate measurement

GPI FAT4

1.28e-03101602EFO_0021020
Diseaseobesity (is_implicated_in)

GHRL BBS4 GFPT1 MTTP

1.54e-03911604DOID:9970 (is_implicated_in)
Diseasemicrofibrillar-associated protein 2 measurement

A2ML1 C1R

1.56e-03111602EFO_0801801
Diseaseage at menarche

COL11A1 ARHGAP40 TTC28 RB1CC1 LRP1B ADCY8 MADD PDILT NR5A1 CADPS2

1.56e-0359416010EFO_0004703
DiseaseCachexia

GHRL PTGS2

1.86e-03121602C0006625
Diseaseurate measurement, bone density

TTC28 DNAH14 PCDH17 ITPR1 ASB3 A2ML1 EIF2AK4 CADPS2 FAM135A ATP2B4

2.11e-0361916010EFO_0003923, EFO_0004531
Diseaselysophosphatidylcholine 15:0 measurement

LRP1B PKHD1

2.55e-03141602EFO_0020941
DiseaseGDH/6PGL endoplasmic bifunctional protein measurement

HLA-DRB1 ERGIC2

2.55e-03141602EFO_0801619
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

HLA-DRB1 CPT1A RRN3

2.69e-03511603EFO_0022302
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

HLA-DRB1 CPT1A RRN3 MTTP

3.08e-031101604EFO_0008317, EFO_0008591, EFO_0008596
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

HLA-DRB1 CPT1A RRN3 MTTP

3.08e-031101604EFO_0004574, EFO_0008317, EFO_0008596
DiseaseSchizophrenia

HLA-DRB1 APBA2 SRR RB1CC1 PTGS2 PCDH17 MTHFD1 PIK3CB PLA2G4B VPS35 ERVK-8 CADPS2

3.25e-0388316012C0036341
Diseaseinterleukin-6 measurement

HLA-DRB1 MDGA2 ITPR1 ATP2B4

3.28e-031121604EFO_0004810
Diseasesarcoidosis (is_implicated_in)

HLA-DRB1 PTGS2

3.34e-03161602DOID:11335 (is_implicated_in)
Diseasecathepsin L1 measurement

MAN2B1 HLA-DRB1

3.34e-03161602EFO_0010619
Diseasestroke outcome severity measurement

OMA1 COL11A1 MDGA2 TTC7B

3.50e-031141604EFO_0009603
DiseaseIGA glomerulonephritis

HLA-DRB1 ITGAX VAV3

3.88e-03581603EFO_0004194
Diseasesphingosine 1-phosphate measurement

OMA1 ITPR1

4.22e-03181602EFO_0800185
DiseaseGastric ulcer

GHRL PTGS2

4.22e-03181602C0038358
DiseasePROSTATE CANCER, HEREDITARY, 1

HAUS6 TTC28 PAX9

4.27e-03601603C4722327
Diseasemean reticulocyte volume

CUL4A PGS1 DPY19L3 ABCB7 HLA-DRB1 RPS6KA1 ABCB4 ASB3 LSM4 AFDN NR5A1

4.35e-0379916011EFO_0010701
Diseaseproliferative diabetic retinopathy

CPM LSM4 PRKAG2

4.47e-03611603EFO_0009322
Diseasewellbeing measurement

OMA1 FAT4 HLA-DRB1 TRPC4 ZMYND8 MUC19 TEX15 CSE1L PKHD1 PCDH9

4.63e-0369216010EFO_0007869
Diseaselongevity

APBA2 TEX15 CSE1L MTHFD1 PKHD1 CRYBG1

4.65e-032841606EFO_0004300
Diseasehepatitis B virus infection

HLA-DRB1 HLA-DRB3

4.70e-03191602EFO_0004197
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

GFPT1 MTTP

4.70e-03191602DOID:1168 (biomarker_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

PGS1 HLA-DRB1 CPT1A RRN3 MTTP

4.79e-032001605EFO_0004611, EFO_0020945
Diseasecognitive function measurement

COL11A1 TTC28 ZNF521 COPG2 MDGA2 NKIRAS1 LRP1B PCDH17 CSE1L ST6GALNAC5 ASB3 PKHD1 CRYBG1 VAV3 PRKAG2 EXOC4

5.03e-03143416016EFO_0008354
DiseaseColorectal Carcinoma

OMA1 RELCH PTGS2 ADCY8 ABCB4 CSE1L PDILT PKHD1 C2CD6 EXOC4

5.11e-0370216010C0009402
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

PGS1 HLA-DRB1 CPT1A RRN3

5.13e-031271604EFO_0008595, EFO_0020947
Diseaseunipolar depression, memory performance, cognitive function measurement

KIAA0319 ST6GALNAC5

5.21e-03201602EFO_0003761, EFO_0004874, EFO_0008354
Diseasetaste liking measurement

HLA-DRB1 PCDH17 PKHD1 CADPS2 PCDH9 EXOC4 KLB

5.40e-033881607EFO_0010155

Protein segments in the cluster

PeptideGeneStartEntry
KQGAIYHGLATLLNQ

AFDN

1091

P55196
LLNENNNTGIIKGHY

ADCY8

1211

P40145
FLQGFKGQLIHTYNK

NT5C3B

191

Q969T7
QALQHRSQYFEGVVK

PRKAG2

496

Q9UGJ0
GIYQKAFEHLGNALT

BBS4

216

Q96RK4
YKELISGHGFAQNQL

CDC20

411

Q12834
LHQEGKFVELGLSNY

AKR7L

131

Q8NHP1
LHQEGKFVELGLSNY

AKR7A3

131

O95154
GLVYKVQQHNGIIFQ

EIF2AK4

1316

Q9P2K8
NQSIGGVILFHETLY

ALDOB

71

P05062
GNYTVTGLKQRQHLE

CD160

136

O95971
YGLLHGLQAAVAQQD

ARHGEF2

746

Q92974
LYVNKVAGNFHITVG

ERGIC2

176

Q96RQ1
NNGLIHYSIIKGNEE

FAT4

1241

Q6V0I7
LKNHLVFLVIYGTNG

A2ML1

371

A8K2U0
NLTQLIGGAQELHAY

AP1G2

441

O75843
GVSYILVGENLINFH

CPT1A

721

P50416
DLKYQLGFSVQNGII

APBA2

666

Q99767
VQTAKHYGNLGRLYQ

APPBP2

426

Q92624
LIIQNVNKSHGGIYV

CD79A

91

P11912
LQILNNYLQFEVSHG

CELSR1

1741

Q9NYQ6
FLLSLLVLGAHQQQY

SLC7A4

521

O43246
TLVQGFHGLIYDNKT

DPY19L3

106

Q6ZPD9
IGGSVHLIVNNQLGY

DHTKD1

356

Q96HY7
GYQLIEGNQVLHSFT

C1R

341

P00736
NDIFQYLEHILGFQK

FAM200A

366

Q8TCP9
IHGEKNVFSGIYRNI

ATP2B4

981

P23634
FGYIHAIKLAQQGNL

AP4E1

96

Q9UPM8
GNFNYIEFTRILKHG

MYL12A

151

P19105
LHLFSINGKYLGSQI

NBEAL1

2571

Q6ZS30
RFTKGLYVLQVHENN

PCDH17

471

O14917
LLHLVGNVQAGDYVL

TP53I3

131

Q53FA7
YVAEGQKQGQLRSLH

ITGAX

831

P20702
LYITGNGVLFQHVKN

KCTD19

316

Q17RG1
NLFGVQVQYKHLSEL

ORC4

36

O43929
YKIAIQHQVLVVNGG

RB1CC1

36

Q8TDY2
QLYRDFGNHQVTGKD

RELCH

306

Q9P260
ILRNKIGNLAQQGHY

PAX9

126

P55771
LQTLGHNLFGIYQKY

ITLN1

176

Q8WWA0
INHNAVLYKVFVVGE

ITPK1

191

Q13572
QKFGHGSVEYLALNI

LRP1B

4141

Q9NZR2
GKSHIGLVYSQQINE

MADD

1401

Q8WXG6
LGTVIQYGNVIQLLH

ITPR1

111

Q14643
THGRNVQYIKFLQTI

ITPR1

1311

Q14643
LYEFKVIVEGQNAHG

KIAA0319L

376

Q8IZA0
GFLQQLHTVGLIVQY

INPP4B

651

O15327
GKTAILEQLLYGNHT

NKIRAS1

16

Q9NYS0
DVLVQSNVYGNLKHG

BEND2

701

Q8NDZ0
LGSVQIHLYEVIQKG

C2CD6

201

Q53TS8
IQSFLLSIYNEHGIQ

COL11A1

111

P12107
FEKVLQSHGQDYLVG

GSTA3

136

Q16772
QSHGQDYLVGNKLSR

GSTA3

141

Q16772
LHYFKNVVLVGSLQD

FAM135A

1411

Q9P2D6
TQGQLYKVFLHGSQG

PLXNB3

416

Q9ULL4
SNLNIFQYIGKAGLH

MTTP

646

P55157
FQYIGKAGLHGSQVV

MTTP

651

P55157
HTVGLYLILKFQNGI

MUC19

1371

Q7Z5P9
VQHYELLNGQSVFGL

PCDH9

176

Q9HC56
IGLQHIKVYLFDNSV

PGS1

216

Q32NB8
KYGNLGHVNIGAIQE

COG8

536

Q96MW5
GRDHKYAVEIQGQLN

MEGF8

796

Q7Z7M0
QIGLANFVGIIDNHY

HERVK_113

421

P63132
GKTSILEQLLYGNHV

NKIRAS2

16

Q9NYR9
LYDFNKILENGRIHG

MPHOSPH10

46

O00566
QQFIYNNSILLEHGI

PTGS2

391

P35354
FVKVIQGYIANQILH

TUBGCP6

1676

Q96RT7
NGQHAFYQLIHQGTK

GPI

386

P06744
DYNLHGAFQQLQLLG

PLA2G4B

641

P0C869
QIGLANFVGIIDNHY

ERVK-7

421

P63135
KIGLANFVGIIDNHY

ERVK-6

421

Q9BXR3
QHIGVLNVYLRLKGQ

MDGA2

846

Q7Z553
GTHQQLLAQKGIYFS

ABCB4

1261

P21439
SGHDLQGKLQLRYQE

NDUFA7

16

O95182
QIGLANFVGIIDNHY

ERVK-18

421

Q9QC07
QVVQKYLFQIINGIG

CDKL2

101

Q92772
LFIYFRNQKGHSGLQ

HLA-DRB3

246

P79483
LYKLQDGNHLLFQQV

GSTA4

41

O15217
SLQQHKFQYIFEGLG

EXOC4

831

Q96A65
LKFNQCYGVLGVLDH

FAXDC2

281

Q96IV6
FGIVNILLKYGAQIN

ASB3

331

Q9Y575
FGHFYGTIQIQKRQQ

CCPG1

231

Q9ULG6
EKGINISNRIHYNIF

FBH1

396

Q8NFZ0
KYGHEGTVLNNKLFI

KLHL15

416

Q96M94
EYIKQVHLGVKGQVF

CPM

306

P14384
DVGIKLSGVQYQQHS

GHRL

81

Q9UBU3
YQQHSQALGKFLQDI

GHRL

91

Q9UBU3
YLNGVIHDIKNGLNS

GLT6D1

246

Q7Z4J2
GHITYQEFLQKLGIN

EFCAB6

901

Q5THR3
GKQHVGQDILVFYVN

CENPC

881

Q03188
QFQGNLAEGLHLYIV

CDHR3

131

Q6ZTQ4
GLSINFAKVLHGEQY

HSD17B4

396

P51659
GHNLLVSELYNQLKF

CUL4A

711

Q13619
IGQLNVHYLRNKGVG

CCDC13

451

Q8IYE1
QRIHQGLIFYEKLLG

IL23A

91

Q9NPF7
NLYAANGIGAVLAHK

CTR9

646

Q6PD62
LFIYFRNQKGHSGLQ

HLA-DRB1

246

P01911
GGQEQQYHSKIDDLI

CADPS2

1101

Q86UW7
ILYLLNQGEHFGTTE

COPG2

51

Q9UBF2
LFIYFRNQKGHSGLQ

HLA-DRB4

246

P13762
HGQYSVENAILIKNG

DNAH14

2506

Q0VDD8
ILHKQASGNIVYGVF

IFI16

306

Q16666
YGIKNDIQHAGVQYI

MAN2B1

86

O00754
LVELKNGETYNGHLV

LSM4

16

Q9Y4Z0
LHIGNVYEAGKLNLL

HAUS6

291

Q7Z4H7
GNLAAVYTVGHNLIK

KLB

261

Q86Z14
GNYSLLVKNIHNGVS

HGSNAT

161

Q68CP4
YNQLQVIFQGIEGKI

CACTIN

411

Q8WUQ7
KNYSLHIEEQGEGVQ

CCDC168

4916

Q8NDH2
IKGGTQYDQNHIILN

CRYBG1

1691

Q9Y4K1
NGIHYKLQLLYSNGV

EBF3

106

Q9H4W6
GREGITLNKYNQQYH

GRAMD2A

61

Q8IUY3
GSGAIQTIKQYNYLH

CDKN3

176

Q16667
IYNGGNHKLTQIAKV

ZMYND8

226

Q9ULU4
FQIYLNLAHVTNAGI

MEP1B

461

Q16820
IGLVQALGAHLYQNV

MTHFD1

391

P11586
NQYHQLKDITLGTLG

MCOLN2

136

Q8IZK6
HGQLDDLIFIFYKNG

PPEF2

181

O14830
NGLVNASYTKLQLHG

PARP6

486

Q2NL67
HFGGYQVEKQHQQIL

CFAP221

66

Q4G0U5
QQAVLYKGEHTLKGF

PDILT

471

Q8N807
HKQLLSGNLKEGLQY

RRN3

471

Q9NYV6
VIYGISLQGLHNQLL

VARS1

876

P26640
IYRQVQHGKEGSILL

NR5A1

311

Q13285
NLGNGIALLVDSQHY

TOP6BL

166

Q8N6T0
NEFIVIHNGIITNYK

GFPT1

116

Q06210
LQHVGSNIFLLQVLY

SLC22A10

371

Q63ZE4
ANHGGDIIDYLLNQL

PSMD1

451

Q99460
GKGQVYNNLHLLSQV

ST6GALNAC5

181

Q9BVH7
SKQHLGGSQQLLNYK

SEMG2

96

Q02383
AILGKYQLNVKTGNH

TGM4

111

P49221
GLKVDSNVFYNILGH

PKHD1

2251

P08F94
EVIGLQNKNYSAHLG

SLCO1B7

461

G3V0H7
NHGQALTYAAKLEGI

SRR

86

Q9GZT4
TYDFIHVIQQGKTGN

PIK3CB

961

P42338
VQVNHIVNKYQGLGV

OMA1

41

Q96E52
NVHFEYIEGQKVLSG

ABCB7

476

O75027
TSLQHRYQQLGAGLK

BRINP2

366

Q9C0B6
FQIRDSKGLHNVVYG

CNOT1

366

A5YKK6
QIGLANFVGIIDNHY

ERVK-25

421

P63136
TVQVNFYGDHTKLIL

PLK3

581

Q9H4B4
QTLNVNRLLHIVGYG

TSR1

281

Q2NL82
KANDHQGFYLLNSII

CSE1L

741

P55060
KGNHDGAVQQYIRTI

VPS11

401

Q9H270
CGKGFYLEVKLLQHQ

ZNF549

506

Q6P9A3
ANILLYEVGGNINEH

ARHGAP40

581

Q5TG30
IYQEIILANHFNEGG

RINT1

686

Q6NUQ1
VGHKVFGSLYQDQIL

TUBE1

111

Q9UJT0
VLQQQYNRVGKVEHG

TLN1

431

Q9Y490
QYLILNTARKHFGAG

VPS35

506

Q96QK1
AVQTTGRGQHVQKLY

ZNF521

1051

Q96K83
QIGLANFVGLIDNHY

ERVK-10

421

P10266
KGLASLEQLYLHFNQ

PXDN

131

Q92626
QIGLANFVGIIDNHY

ERVK-8

421

P63133
QIGLANFVGIIDNHY

ERVK-11

421

Q9UQG0
HKQLLSGNLKEGLQY

RRN3P1

96

Q2M238
FKASVYGNSILIQQH

SMC6

131

Q96SB8
YGNSILIQQHISIDG

SMC6

136

Q96SB8
NYEKAISQGHQAFLL

VWA5A

86

O00534
LKGVENVYTQHQPFL

VPS45

456

Q9NRW7
GIEHGNILQYNLAVF

PKHD1L1

2531

Q86WI1
RQGHQEGYINQKIIS

ZNF780B

131

Q9Y6R6
HVQLKQGADYGQISE

USP20

856

Q9Y2K6
NYKGVLLTQEGNLTH

ZNF347

151

Q96SE7
CGKAFGQKYLLVQHQ

ZNF773

196

Q6PK81
QQDLKKGLHLYGTQG

TSPAN4

116

O14817
NGAIKFYEQQLGLAH

TTC28

731

Q96AY4
GNLKHKQYQILAVEG

ZUP1

541

Q96AP4
HVLYFKNGNLTRGVG

TTC7B

226

Q86TV6
GLYHTNAEVKLQGFQ

SH2D3C

791

Q8N5H7
GYLQLKGLSLQAKQH

TTC23

96

Q5W5X9
KHFLNDLYQQGNLIL

TEX15

1276

Q9BXT5
FGLINLYVTNVKAQH

TRPC4

576

Q9UBN4
QGNVIYLEVQKGQFL

SIGLEC16

241

A6NMB1
LIHTQGQNGLEFYCK

VAV3

471

Q9UKW4
YQGEIKQGHKQTLNL

KIAA0319

381

Q5VV43
QLHGKNLVFSDGYVV

RPS6KA1

406

Q15418
AIHLAGLIYKAQFNN

MYO7B

1931

Q6PIF6