Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMRF binding

CREBBP CSRP3

6.76e-056432GO:0043426
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BPTF CHD7 MSH4 EP400

1.59e-04127434GO:0008094
GeneOntologyMolecularFunctioncAMP response element binding

ATF2 CREB5

2.95e-0412432GO:0035497
GeneOntologyMolecularFunctioncAMP response element binding protein binding

ATF2 CREBBP

2.95e-0412432GO:0008140
GeneOntologyMolecularFunctionleucine zipper domain binding

CDC5L ATF2

4.05e-0414432GO:0043522
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

BPTF CHD7 USF3 HIVEP1 CDC5L ATF2 ZNF251 CREBBP CREB5 ZNF280C

8.68e-0414594310GO:0000977
GeneOntologyMolecularFunctionLRR domain binding

CDC5L ATF2

1.02e-0322432GO:0030275
MousePhenoembryonic lethality during organogenesis, complete penetrance

MAP3K20 BPTF TAB2 CHD7 EP400 WNK1 MAP4K4 CREBBP CIAO3 UBR4

7.22e-067003610MP:0011098
MousePhenoembryonic lethality during organogenesis

MAP3K20 BPTF TAB2 CHD7 POGZ EP400 WNK1 MAP4K4 CREBBP CIAO3 UBR4

7.74e-068763611MP:0006207
MousePhenostereotypic behavior

SLC6A3 CHD7 DST ATF2 CREBBP ATP6V0A4

1.59e-05214366MP:0001408
MousePhenoatrioventricular cushion hypoplasia

CHD7 EPHA3

9.61e-056362MP:0030992
MousePhenoabnormal head movements

CHD7 DST ATF2 ATP6V0A4

1.37e-04103364MP:0000436
DomainTF_CRE-BP1-typ

ATF2 CREB5

1.48e-053422IPR016378
DomainSANT

CHD7 CDC5L EP400

1.93e-0450423SM00717
DomainSANT/Myb

CHD7 CDC5L EP400

2.16e-0452423IPR001005
DomainSAM

MAP3K20 ZCCHC14 EPHA3

1.35e-0397423IPR001660
DomainBromodomain_CS

BPTF CREBBP

1.55e-0326422IPR018359
DomainZINC_FINGER_C2H2_2

POGZ HIVEP1 CBLL2 ATF2 ZNF251 CREB5 ZNF280C

1.56e-03775427PS50157
DomainZINC_FINGER_C2H2_1

POGZ HIVEP1 CBLL2 ATF2 ZNF251 CREB5 ZNF280C

1.59e-03777427PS00028
Domain-

MAP3K20 ZCCHC14 EPHA3

1.74e-031064231.10.150.50
DomainZnf_C2H2-like

POGZ HIVEP1 CBLL2 ATF2 ZNF251 CREB5 ZNF280C

1.82e-03796427IPR015880
DomainZnf_C2H2

POGZ HIVEP1 CBLL2 ATF2 ZNF251 CREB5 ZNF280C

1.94e-03805427IPR007087
DomainZnF_C2H2

POGZ HIVEP1 CBLL2 ATF2 ZNF251 CREB5 ZNF280C

1.98e-03808427SM00355
DomainSAM/pointed

MAP3K20 ZCCHC14 EPHA3

2.30e-03117423IPR013761
DomainSNF2_N

CHD7 EP400

2.35e-0332422PF00176
DomainSNF2_N

CHD7 EP400

2.35e-0332422IPR000330
DomainbZIP_1

ATF2 CREB5

2.65e-0334422PF00170
DomainDNA/RNA_helicase_DEAH_CS

CHD7 EP400

2.80e-0335422IPR002464
DomainTF_DNA-bd

ATF2 CREB5

3.13e-0337422IPR008917
DomainBROMODOMAIN_1

BPTF CREBBP

3.13e-0337422PS00633
DomainDEAH_ATP_HELICASE

CHD7 EP400

3.30e-0338422PS00690
DomainMYB_LIKE

CDC5L EP400

3.30e-0338422PS50090
DomainBromodomain

BPTF CREBBP

3.30e-0338422PF00439
DomainBROMODOMAIN_2

BPTF CREBBP

3.83e-0341422PS50014
DomainBROMO

BPTF CREBBP

4.02e-0342422SM00297
DomainBromodomain

BPTF CREBBP

4.02e-0342422IPR001487
Domain-

BPTF CREBBP

4.02e-03424221.20.920.10
DomainBRLZ

ATF2 CREB5

6.10e-0352422SM00338
DomainBZIP

ATF2 CREB5

6.33e-0353422PS50217
DomainBZIP_BASIC

ATF2 CREB5

6.33e-0353422PS00036
DomainbZIP

ATF2 CREB5

6.56e-0354422IPR004827
DomainKinase-like_dom

MAP3K20 DST WNK1 MAP4K4 EPHA3

7.09e-03542425IPR011009
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION

ATF2 CREBBP CREB5

2.21e-0613293M47595
PathwayKEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY

TAB2 ATF2 CREB5

1.54e-0524293M47568
PathwayBIOCARTA_PCAF_PATHWAY

ATF2 CREBBP

1.46e-049292MM1533
PathwayWP_HEPATITIS_B_INFECTION

TAB2 ATF2 CREBBP CREB5

2.44e-04151294M39801
PathwayWP_MAPK_SIGNALING_PATHWAY

MAP3K20 TAB2 MAP4K4 ATF2

3.04e-04160294MM15990
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION

ATF2 CREB5

3.14e-0413292M47674
PathwayBIOCARTA_PCAF_PATHWAY

ATF2 CREBBP

3.14e-0413292M22007
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

ATF2 CREB5

4.82e-0416292M47551
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

5.45e-0417292M47514
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

6.13e-0418292M47516
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

7.59e-0420292M47517
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY

ATF2 CREB5

8.38e-0421292M47792
PathwayKEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY

ATF2 CREB5

1.01e-0323292M47799
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

ATF2 CREB5

1.01e-0323292M47512
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ATF2 CREB5

1.10e-0324292M47520
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

ATF2 CREB5

1.10e-0324292M47509
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

ATF2 CREB5

1.19e-0325292M47510
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

ATF2 CREB5

1.19e-0325292M47511
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

ATF2 CREB5

1.29e-0326292M47553
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ATF2 CREB5

1.39e-0327292M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ATF2 CREB5

1.39e-0327292M47519
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

ATF2 CREB5

1.49e-0328292M47647
PathwayKEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

ATF2 CREB5

1.49e-0328292M47508
PathwayWP_MAPK_SIGNALING

MAP3K20 TAB2 MAP4K4 ATF2

1.52e-03246294M39597
PathwayKEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY

ATF2 CREB5

1.60e-0329292M47764
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

1.60e-0329292M47515
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

ATF2 CREB5

1.60e-0329292M47627
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

1.83e-0331292M47507
PathwayPID_WNT_NONCANONICAL_PATHWAY

TAB2 CHD7

1.95e-0332292M23
PathwayKEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF2 CREB5

1.95e-0332292M47506
PathwayKEGG_MAPK_SIGNALING_PATHWAY

MAP3K20 TAB2 MAP4K4 ATF2

2.06e-03267294M10792
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY

ATF2 CREB5

2.07e-0333292M47550
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

EP400 ATF2 CREBBP NSD3

2.20e-03272294M29619
PathwayREACTOME_RHOV_GTPASE_CYCLE

DST ARHGAP12

2.60e-0337292M41819
PathwayREACTOME_RHOV_GTPASE_CYCLE

DST ARHGAP12

2.60e-0337292MM15610
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

BPTF POGZ CDC5L GTF3C1 EP400 MAP4K4 CREBBP PDLIM7 NSD3

2.47e-0854944938280479
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

BPTF POGZ CDC5L GTF3C1 EP400 NSD3

3.59e-0815044628242625
Pubmed

A human MAP kinase interactome.

USF3 POGZ HIVEP1 DST WNK1 MAP4K4 CREBBP NSD3

1.57e-0748644820936779
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ZCCHC14 TAB2 CHD7 DST CDC5L WNK1

3.94e-0722544612168954
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DYNC1LI1 BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 MAP4K4 ATF2

4.51e-0777444915302935
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

DYNC1LI1 CHD7 POGZ CDC5L GTF3C1 EP400 NSD3

6.06e-0739444727248496
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MAP3K20 DYNC1LI1 CHD7 POGZ DST CDC5L GTF3C1 EP400 CREBBP PDLIM7 UBR4

6.97e-071353441129467282
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DYNC1LI1 BPTF CHD7 POGZ DST CDC5L GTF3C1 EP400 MAP4K4 NSD3

7.73e-071082441038697112
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAP3K20 ZCCHC14 TAB2 HIVEP1 DST WNK1 MAP4K4 TRIP11 NSD3

1.09e-0686144936931259
Pubmed

The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.

ATF2 CREB5

1.56e-06244237816820
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZCCHC14 DYNC1LI1 CHD7 CDC5L EP400 WNK1 MAP4K4 VPS13C

3.40e-0673344834672954
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF CHD7 POGZ EP400

3.81e-068344428794006
Pubmed

LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.

DST AFF3

4.69e-0634428662235
Pubmed

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.

EP400 CREBBP

4.69e-0634429590171
Pubmed

The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors.

ATF2 CREB5

4.69e-06344219948881
Pubmed

Interaction network of human early embryonic transcription factors.

BPTF CHD7 POGZ HIVEP1 EP400 CREBBP

5.17e-0635144638297188
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

DYNC1LI1 BPTF DST CDC5L TRIP11 ZNF280C

5.98e-0636044633111431
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

DYNC1LI1 BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 ATF2 CREBBP

8.20e-06110344934189442
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TAB2 CHD7 HIVEP1 EP400 WNK1 TRIP11 CREBBP

8.49e-0658844738580884
Pubmed

CBP alleviates the intramolecular inhibition of ATF-2 function.

ATF2 CREBBP

9.37e-0644429786917
Pubmed

[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin.

ATF2 CREBBP

9.37e-06444215735738
Pubmed

A novel role of sodium butyrate in the regulation of cancer-associated aromatase promoters I.3 and II by disrupting a transcriptional complex in breast adipose fibroblasts.

ATF2 CREBBP

9.37e-06444216303757
Pubmed

Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.

ATF2 CREB5

9.37e-0644428440710
Pubmed

Binding and modulation of p53 by p300/CBP coactivators.

EP400 CREBBP

9.37e-0644429194565
Pubmed

Prostaglandin E2 signalling pathway in human T lymphocytes from healthy and conjunctiva basal cell carcinoma-bearing subjects.

ATF2 CREBBP

9.37e-06444211564156
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

DYNC1LI1 BPTF CHD7 CDC5L EP400 UBR4

1.03e-0539644626687479
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BPTF CHD7 POGZ HIVEP1 GTF3C1 NSD3 ZNF280C

1.05e-0560844736089195
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

CHD7 POGZ MSH4 HIVEP1 EP400 CREBBP

1.06e-0539844635016035
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

BPTF POGZ GTF3C1 EP400 ATF2 CREBBP CREB5 UBR4

1.06e-0585744825609649
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

BPTF TAB2 CHD7 CDC5L GTF3C1 EP400

1.27e-0541144635182466
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CHD7 POGZ HIVEP1 DST GTF3C1 UBR4

1.40e-0541844634709266
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TAB2 CHD7 HIVEP1 TRIP11 ZNF251 CREBBP UBR4

1.44e-0563844731182584
Pubmed

Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription.

ATF2 CREBBP

1.56e-0554429659924
Pubmed

Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

ATF2 CREBBP

1.56e-05544217296604
Pubmed

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

BPTF NSD3

1.56e-05544226626481
Pubmed

Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2.

MAP4K4 ATF2

1.56e-05544217500068
Pubmed

Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway.

SLC6A3 EPHA3

1.56e-05544219576892
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

CHD7 USF3 EP400 WNK1 PDLIM7 UBR4

1.64e-0543044635044719
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

CHD7 POGZ GTF3C1 ZNF280C

1.93e-0512544432891193
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CHD7 HIVEP1 EP400 ATF2 CREBBP

2.22e-0526844533640491
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BPTF CHD7 POGZ HIVEP1 CDC5L EP400 NSD3 ZNF280C

2.30e-0595444836373674
Pubmed

Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.

TAB2 ATF2

2.34e-05644226391660
Pubmed

The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A.

ATF2 CREBBP

2.34e-05644210327051
Pubmed

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

TAB2 PDLIM7

2.34e-05644216446357
Pubmed

Ubiquitin-specific protease 14 promotes prostate cancer progression through deubiquitinating the transcriptional factor ATF2.

ATF2 CREBBP

2.34e-05644231964530
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

BPTF CHD7 POGZ DST CDC5L GTF3C1 EP400 ATF2 NSD3

2.91e-05129444930804502
Pubmed

MAP4K4 and WT1 mediate SOX6-induced cellular senescence by synergistically activating the ATF2-TGFβ2-Smad2/3 signaling pathway in cervical cancer.

MAP4K4 ATF2

3.27e-05744238383842
Pubmed

Constitutive activation of TAK1 by HTLV-1 tax-dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-kappaB.

TAB2 ATF2

3.27e-05744217626013
Pubmed

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

ATF2 CREBBP

3.27e-0574427774816
Pubmed

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance.

CHD7 EPHA3

3.27e-05744224728844
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

BPTF CHD7 POGZ EP400

3.55e-0514644423892456
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

TAB2 HIVEP1 DST WNK1 TRIP11 CSRP3

3.68e-0549744623414517
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CHD7 MARCHF4 VPS13C UBR4

4.26e-0515344410718198
Pubmed

Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.

MAP3K20 ATF2

4.36e-05844212761180
Pubmed

Casein kinase II interacts with the bZIP domains of several transcription factors.

ATF2 CREBBP

4.36e-0584429685505
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

BPTF CHD7 EP400 CREBBP

4.71e-0515744430186101
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

POGZ DST EP400 MAP4K4 VPS13C ZNF280C

5.20e-0552944614621295
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DYNC1LI1 POGZ HIVEP1 CDC5L GTF3C1 MAP4K4 VPS13C UBR4 ZNF280C

6.15e-05142544930948266
Pubmed

Human transcription factor protein interaction networks.

BPTF CHD7 POGZ HIVEP1 DST GTF3C1 EP400 CREBBP UBR4

6.28e-05142944935140242
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZCCHC14 BPTF POGZ HIVEP1 CDC5L ATF2 ZNF280C

6.45e-0580844720412781
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

BPTF POGZ GTF3C1 EP400 UBR4

6.98e-0534144532971831
Pubmed

SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells.

EP400 CREBBP

6.99e-051044218087039
Pubmed

The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration.

CHD7 EPHA3

6.99e-051044234732824
Pubmed

Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo.

TAB2 ATF2

8.54e-05114429162092
Pubmed

Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.

BPTF DST

8.54e-051144219233709
Pubmed

pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.

TAB2 ATF2

8.54e-051144210066798
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

CHD7 POGZ CDC5L GTF3C1 EP400 CREB5

8.89e-0558344629844126
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIVEP1 DST ZNF251 CREBBP PDLIM7 UBR4

9.57e-0559144615231748
Pubmed

Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.

WNK1 CREBBP

1.02e-041244212748276
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

DYNC1LI1 BPTF CDC5L GTF3C1 NSD3

1.02e-0437044522922362
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

MAP3K20 MAP4K4 EPHA3

1.35e-047844317192257
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

DST MAP4K4 TRIP11 UBR4

1.50e-0421244433853758
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BPTF CHD7 POGZ DST GTF3C1 UBR4

1.65e-0465344622586326
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MAP3K20 CHD7 DST GTF3C1 EP400

1.65e-0441044526949251
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

POGZ EP400 CREBBP AFF3

1.80e-0422244437071664
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

POGZ DST MAP4K4 TRIP11 ZNF251 CREBBP CIAO3 UBR4

1.84e-04128544835914814
Pubmed

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

DYNC1LI1 CHD7

1.86e-041644210932191
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

POGZ CDC5L GTF3C1 MAP4K4 ZNF251 CREBBP

1.89e-0467044622990118
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

BPTF GTF3C1

2.10e-041744221653943
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

BPTF GTF3C1

2.36e-041844217846119
Pubmed

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

TAB2 CREBBP

2.36e-041844215829968
Pubmed

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.

ATF2 CREB5

2.36e-041844229996942
Pubmed

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.

ATF2 CREBBP

2.36e-04184429858769
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MAP3K20 DST WNK1 MAP4K4 PDLIM7

2.44e-0444644524255178
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZCCHC14 POGZ HIVEP1 GTF3C1 ATF2 CREBBP

2.57e-0470944622988430
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BPTF CDC5L GTF3C1 EP400 CREBBP UBR4 NSD3

2.62e-04101444732416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

BPTF DST CDC5L GTF3C1 EP400 MAP4K4 PDLIM7

2.78e-04102444724711643
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

MAP3K20 TAB2 POGZ WNK1 MAP4K4 PDLIM7 ARHGAP12

3.02e-04103844726673895
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

BPTF CHD7 CDC5L GTF3C1 EP400

3.07e-0446944527634302
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

DYNC1LI1 BPTF DST EP400 ZNF280C

3.16e-0447244538943005
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TAB2 MAP4K4 TRIP11 PDLIM7

3.42e-0426344434702444
Pubmed

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

MAP4K4 ATF2

3.56e-042244216751104
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

CHD7 NSD3 EPHA3

3.61e-0410944333554859
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

BPTF CHD7 EP400 ZNF280C

4.51e-0428344430585729
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

BPTF POGZ ATF2

4.67e-0411944323508102
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

DYNC1LI1 GTF3C1 WNK1 UBR4

4.82e-0428844423383273
Pubmed

Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development.

ATF2 CREBBP

4.99e-042644217177285
Pubmed

Parkinson Disease Overview

SLC6A3 VPS13C

5.38e-042744220301402
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

DYNC1LI1 BPTF POGZ GTF3C1 NSD3

5.50e-0453344530554943
Pubmed

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.

WNK1 ARHGAP12

5.79e-042844238324473
InteractionH2BC21 interactions

BPTF CHD7 USF3 POGZ EP400 MAP4K4 ATF2 CREBBP NSD3 ZNF280C

1.55e-066964310int:H2BC21
InteractionTERF2IP interactions

BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 CREBBP NSD3 ZNF280C

2.00e-06552439int:TERF2IP
InteractionWWTR1 interactions

BPTF POGZ CDC5L GTF3C1 EP400 MAP4K4 CREBBP PDLIM7

2.64e-06422438int:WWTR1
InteractionHNF1B interactions

BPTF CHD7 POGZ HIVEP1 EP400 CREBBP

2.96e-06190436int:HNF1B
InteractionFOSB interactions

POGZ ATF2 CREBBP CREB5

3.55e-0649434int:FOSB
InteractionFEV interactions

CHD7 POGZ HIVEP1 GTF3C1 EP400 CREBBP

4.34e-06203436int:FEV
InteractionYY1 interactions

BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 ATF2 CREBBP

4.53e-06454438int:YY1
InteractionETS1 interactions

BPTF HIVEP1 EP400 ATF2 CREBBP

5.76e-06121435int:ETS1
InteractionDUXB interactions

BPTF CHD7 POGZ

7.22e-0618433int:DUXB
InteractionPAX6 interactions

BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 CREBBP

1.13e-05366437int:PAX6
InteractionASF1A interactions

CHD7 POGZ HIVEP1 GTF3C1 EP400 NSD3

1.39e-05249436int:ASF1A
InteractionYWHAH interactions

MAP3K20 ZCCHC14 TAB2 HIVEP1 DST WNK1 MARCHF4 MAP4K4 TRIP11 CREBBP NSD3

1.42e-0511024311int:YWHAH
InteractionFOSL1 interactions

TAB2 ATF2 CREBBP CREB5

1.49e-0570434int:FOSL1
InteractionFBXO42 interactions

TAB2 CHD7 HIVEP1 EP400 WNK1 TRIP11

1.74e-05259436int:FBXO42
InteractionHNF4A interactions

BPTF CHD7 POGZ HIVEP1 EP400 CREBBP

2.44e-05275436int:HNF4A
InteractionETV7 interactions

CHD7 HIVEP1 PDLIM7

2.55e-0527433int:ETV7
InteractionINSYN1 interactions

MAP4K4 TRIP11 ATF2 CREB5 UBR4

2.91e-05169435int:INSYN1
InteractionEGR2 interactions

CHD7 POGZ HIVEP1 EP400 CREBBP

3.08e-05171435int:EGR2
InteractionPAX2 interactions

CHD7 POGZ HIVEP1 NSD3

3.21e-0585434int:PAX2
InteractionNFYC interactions

USF3 POGZ HIVEP1 DST EP400

3.63e-05177435int:NFYC
InteractionNHLH1 interactions

BPTF HIVEP1 EP400 CSRP3

3.68e-0588434int:NHLH1
InteractionAPEX1 interactions

BPTF CFAP74 CHD7 POGZ HIVEP1 GTF3C1 EP400 ATF2 CIAO3 NSD3 ZNF280C

5.31e-0512714311int:APEX1
InteractionMYOD1 interactions

BPTF HIVEP1 EP400 CREBBP CSRP3

5.61e-05194435int:MYOD1
InteractionKLF8 interactions

BPTF CHD7 POGZ HIVEP1 EP400 CREBBP

6.63e-05329436int:KLF8
InteractionPOLR1G interactions

BPTF CHD7 POGZ GTF3C1 EP400 UBR4 NSD3

7.17e-05489437int:POLR1G
InteractionPARP1 interactions

BPTF CHD7 POGZ HIVEP1 CDC5L GTF3C1 EP400 MAP4K4 CREBBP PDLIM7 NSD3

7.28e-0513164311int:PARP1
InteractionH3C3 interactions

BPTF CHD7 POGZ HIVEP1 GTF3C1 NSD3 ZNF280C

7.74e-05495437int:H3C3
InteractionNFIC interactions

ZCCHC14 POGZ HIVEP1 CREBBP NSD3

8.17e-05210435int:NFIC
InteractionJDP2 interactions

ATF2 CREBBP CREB5

9.80e-0542433int:JDP2
InteractionTBXT interactions

CHD7 POGZ HIVEP1 CREBBP

1.08e-04116434int:TBXT
InteractionERG interactions

CHD7 HIVEP1 CDC5L CREBBP UBR4

1.08e-04223435int:ERG
InteractionNFIX interactions

BPTF POGZ HIVEP1 GTF3C1 EP400

1.18e-04227435int:NFIX
InteractionELK3 interactions

CHD7 POGZ HIVEP1 EP400

1.23e-04120434int:ELK3
InteractionKDM1A interactions

CHD7 POGZ HIVEP1 DST CDC5L GTF3C1 EP400 UBR4 ZNF280C

1.36e-04941439int:KDM1A
InteractionELF1 interactions

BPTF POGZ HIVEP1 EP400

1.49e-04126434int:ELF1
InteractionH3-3A interactions

BPTF CHD7 POGZ HIVEP1 GTF3C1 CREBBP NSD3 ZNF280C

1.60e-04749438int:H3-3A
InteractionMYH9 interactions

HIVEP1 DST CDC5L WNK1 CREBBP PDLIM7 CIAO3 EPHA3

1.68e-04754438int:MYH9
InteractionMYB interactions

CHD7 POGZ HIVEP1 CREBBP

1.83e-04133434int:MYB
InteractionH2BC8 interactions

BPTF CHD7 POGZ GTF3C1 EP400 NSD3 ZNF280C

1.98e-04576437int:H2BC8
InteractionH2BC3 interactions

CHD7 POGZ CDC5L EP400 CREBBP NSD3

2.09e-04406436int:H2BC3
InteractionSUPT5H interactions

CHD7 HIVEP1 CDC5L GTF3C1 EP400 UBR4

2.15e-04408436int:SUPT5H
InteractionPOU5F1 interactions

DYNC1LI1 BPTF CHD7 CDC5L EP400 ATF2 UBR4

2.15e-04584437int:POU5F1
InteractionSRF interactions

BPTF POGZ HIVEP1 CREBBP

2.17e-04139434int:SRF
InteractionBRCA1 interactions

BPTF HIVEP1 DST CDC5L MAP4K4 TRIP11 ATF2 CREBBP CREB5 UBR4

2.36e-0412494310int:BRCA1
InteractionZMYM2 interactions

CHD7 POGZ GTF3C1 CREBBP ZNF280C

2.69e-04271435int:ZMYM2
InteractionDUXA interactions

BPTF CHD7

2.90e-0412432int:DUXA
InteractionSPATA12 interactions

POGZ CREB5

2.90e-0412432int:SPATA12
InteractionMECP2 interactions

DYNC1LI1 BPTF CHD7 POGZ DST CDC5L GTF3C1 EP400 MAP4K4 NSD3

3.00e-0412874310int:MECP2
InteractionBAG2 interactions

BPTF TAB2 CDC5L WNK1 MARCHF4 CREBBP VPS13C

3.16e-04622437int:BAG2
InteractionNUP43 interactions

BPTF POGZ HIVEP1 DST EP400 NSD3 ZNF280C

3.25e-04625437int:NUP43
InteractionMAPK10 interactions

GTF3C1 ATF2 CREBBP

3.29e-0463433int:MAPK10
InteractionELF2 interactions

BPTF POGZ HIVEP1 EP400

3.37e-04156434int:ELF2
InteractionH3-4 interactions

BPTF ANKRD18A USF3 POGZ CREBBP NSD3

3.54e-04448436int:H3-4
InteractionCBX3 interactions

CHD7 POGZ GTF3C1 EP400 MAP4K4 NSD3 ZNF280C

3.97e-04646437int:CBX3
InteractionMACROH2A1 interactions

BPTF POGZ CDC5L GTF3C1 ATF2 NSD3

3.99e-04458436int:MACROH2A1
InteractionSMARCA4 interactions

BPTF CHD7 CDC5L EP400 CREBBP NSD3

4.17e-04462436int:SMARCA4
InteractionSP7 interactions

CHD7 POGZ HIVEP1 EP400 CREBBP

4.55e-04304435int:SP7
InteractionFOS interactions

HIVEP1 EP400 ATF2 CREBBP CREB5

5.12e-04312435int:FOS
InteractionTLX1 interactions

CHD7 POGZ HIVEP1 CREBBP

5.21e-04175434int:TLX1
InteractionRBCK1 interactions

TAB2 CREBBP PDLIM7 CREB5

5.32e-04176434int:RBCK1
InteractionTEAD1 interactions

BPTF CHD7 HIVEP1 CREBBP

5.32e-04176434int:TEAD1
InteractionH3C1 interactions

BPTF CHD7 POGZ GTF3C1 CREBBP UBR4 NSD3 ZNF280C

5.57e-04901438int:H3C1
InteractionLITAF interactions

TAB2 POGZ CREB5

5.93e-0477433int:LITAF
InteractionSFN interactions

MAP3K20 TAB2 DST WNK1 MAP4K4 TRIP11 ATF2

5.99e-04692437int:SFN
InteractionCRABP2 interactions

ZCCHC14 HIVEP1 NSD3

6.16e-0478433int:CRABP2
InteractionLHX2 interactions

CHD7 POGZ HIVEP1 EP400

6.16e-04183434int:LHX2
InteractionLHX3 interactions

CHD7 POGZ HIVEP1 CREBBP

6.41e-04185434int:LHX3
InteractionTHRB interactions

CHD7 ATF2 PDLIM7 CSRP3

6.54e-04186434int:THRB
InteractionH2AC4 interactions

DYNC1LI1 USF3 POGZ GTF3C1 EP400 CREBBP

6.74e-04506436int:H2AC4
InteractionRBBP7 interactions

BPTF HIVEP1 CDC5L EP400 CREBBP VPS13C

6.81e-04507436int:RBBP7
InteractionBRDT interactions

DYNC1LI1 GTF3C1 NSD3

6.87e-0481433int:BRDT
InteractionSTAT2 interactions

EP400 CREBBP UBR4

6.87e-0481433int:STAT2
InteractionEED interactions

BPTF CHD7 POGZ CDC5L GTF3C1 EP400 PDLIM7 VPS13C UBR4 ZNF280C

7.50e-0414454310int:EED
InteractionCHD8 interactions

CHD7 CDC5L NSD3 EPHA3

7.51e-04193434int:CHD8
InteractionKLF12 interactions

CHD7 HIVEP1 GTF3C1 EP400

7.66e-04194434int:KLF12
InteractionKLF5 interactions

HIVEP1 EP400 CREBBP CSRP3

7.81e-04195434int:KLF5
InteractionUSF1 interactions

BPTF GTF3C1 UBR4

7.91e-0485433int:USF1
InteractionPBX1 interactions

MAP3K20 CREBBP UBR4

7.91e-0485433int:PBX1
InteractionADGRA3 interactions

B3GALT2 BRICD5

8.25e-0420432int:ADGRA3
InteractionPOLR1E interactions

CHD7 POGZ HIVEP1 GTF3C1 CREBBP

8.60e-04350435int:POLR1E
InteractionNR3C1 interactions

TAB2 CHD7 POGZ HIVEP1 TRIP11 ZNF251 CREBBP UBR4

9.28e-04974438int:NR3C1
InteractionPRR20B interactions

ZCCHC14 POGZ HIVEP1

9.34e-0490433int:PRR20B
InteractionPRR20C interactions

ZCCHC14 POGZ HIVEP1

9.34e-0490433int:PRR20C
InteractionPRR20D interactions

ZCCHC14 POGZ HIVEP1

9.34e-0490433int:PRR20D
InteractionTAL1 interactions

HIVEP1 CREBBP UBR4

1.03e-0393433int:TAL1
InteractionAR interactions

TAB2 CHD7 HIVEP1 CDC5L EP400 ATF2 CREBBP VPS13C

1.04e-03992438int:AR
InteractionCOIL interactions

CHD7 POGZ HIVEP1 CDC5L GTF3C1 NSD3

1.06e-03552436int:COIL
InteractionZMYND11 interactions

EP400 PDLIM7 CREB5

1.06e-0394433int:ZMYND11
InteractionCEBPA interactions

DYNC1LI1 BPTF CHD7 POGZ HIVEP1 GTF3C1 EP400 ATF2 CREBBP

1.06e-031245439int:CEBPA
InteractionYWHAG interactions

MAP3K20 TAB2 HIVEP1 DST CDC5L WNK1 MAP4K4 TRIP11 ATF2

1.08e-031248439int:YWHAG
InteractionMLLT6 interactions

ATF2 CREB5 NSD3

1.09e-0395433int:MLLT6
InteractionSMC5 interactions

BPTF CHD7 POGZ HIVEP1 CDC5L EP400 NSD3 ZNF280C

1.10e-031000438int:SMC5
InteractionH2AZ1 interactions

BPTF POGZ EP400 MAP4K4 ZNF280C

1.12e-03371435int:H2AZ1
InteractionTRAF3IP1 interactions

TAB2 DST CDC5L

1.13e-0396433int:TRAF3IP1
InteractionYWHAE interactions

MAP3K20 DYNC1LI1 TAB2 HIVEP1 DST CDC5L WNK1 TRIP11 PDLIM7

1.13e-031256439int:YWHAE
InteractionSOX9 interactions

CHD7 EP400 CREBBP

1.16e-0397433int:SOX9
InteractionHSPB7 interactions

BPTF PDLIM7

1.19e-0324432int:HSPB7
InteractionCENPA interactions

BPTF CHD7 HIVEP1 GTF3C1 NSD3

1.20e-03377435int:CENPA
InteractionTFCP2L1 interactions

BPTF POGZ EP400

1.23e-0399433int:TFCP2L1
InteractionANKRD10 interactions

TAB2 POGZ

1.29e-0325432int:ANKRD10
Cytoband2q11.2-q12

MAP4K4 AFF3

8.98e-0724422q11.2-q12
Cytoband16p13.3

BRICD5 PGAP6 CREBBP CIAO3

8.94e-0524444416p13.3
CytobandEnsembl 112 genes in cytogenetic band chr16p13

BRICD5 PGAP6 CREBBP CIAO3

7.40e-04426444chr16p13
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

CHD7 CDC5L EP400

1.46e-0453353532
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BPTF CHD7 GTF3C1 WNK1 MAP4K4 CREBBP VPS13C

1.68e-08180437M8239
CoexpressionGSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN

BPTF USF3 HIVEP1 EP400 MAP4K4 UBR4 NSD3

2.35e-08189437M3112
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ZCCHC14 BPTF POGZ DST ATF2 CREBBP

9.13e-06300436M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

BPTF TAB2 HIVEP1 DST ATF2 CREBBP ARHGAP12

9.95e-06466437M13522
CoexpressionNIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER

SLC6A3 ZCCHC14 CHD7 EP400

1.72e-0594434M18108
CoexpressionMURARO_PANCREAS_BETA_CELL

ZCCHC14 TAB2 CHD7 USF3 DST CDC5L GTF3C1 TRIP11 VPS13C

1.87e-05946439M39169
CoexpressionEIF4E_DN

CD55 EP400 TRIP11 VPS13C

2.20e-05100434M2790
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

CD55 ZCCHC14 DYNC1LI1 HIVEP1 DST ATF2 CREBBP ARHGAP12

4.95e-05822438M6782
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

BPTF TAB2 HIVEP1 DST ATF2 CREBBP CREB5 ARHGAP12

6.59e-05856438M4500
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

TAB2 CHD7 POGZ CDC5L WNK1 MAP4K4 CREBBP ARHGAP12

2.05e-041009438M157
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_B

CD55 DST WNK1 ATF2 ARHGAP12 NSD3

2.06e-04526436M2520
CoexpressionGSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_DN

SLC6A3 MSH4 PDLIM7 AFF3

3.10e-04198434M5307
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

CHD7 USF3 VPS13C NSD3

3.16e-04199434M9238
CoexpressionGSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN

CHD7 WNK1 PGAP6 NSD3

3.16e-04199434M6157
CoexpressionGSE31082_DN_VS_CD8_SP_THYMOCYTE_DN

CHD7 WNK1 CREBBP NSD3

3.22e-04200434M5063
CoexpressionGSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP

USF3 POGZ HIVEP1 WNK1

3.22e-04200434M7776
CoexpressionGSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN

ZCCHC14 CHD7 HIVEP1 CREBBP

3.22e-04200434M8040
CoexpressionGSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP

CD55 HIVEP1 CREBBP ARHGAP12

3.22e-04200434M8042
CoexpressionGSE27786_LIN_NEG_VS_CD4_TCELL_DN

CHD7 POGZ ATF2 NSD3

3.22e-04200434M4773
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MSH4 HIVEP1 DST PDLIM7 CREB5

1.03e-06184445d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD55 BPTF MAP4K4 VPS13C AFF3

1.34e-06194445ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

BPTF DST TRIP11 VPS13C NSD3

1.52e-06199445c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

BPTF TAB2 POGZ WNK1 CREB5

1.52e-06199445358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

BPTF ANKRD18A CHD7 TRIP11 NSD3

1.52e-06199445a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellSevere-B_naive-11|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

REELD1 VPS13C NSD3 AFF3

1.92e-05161444ad3b58e3a8b59a609c8d2d2690d15218d18eabbd
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD7 DST WNK1 MAP4K4

2.66e-051754441ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellBasal|World / shred by cell class for mouse tongue

MAP3K20 DST CREB5 AFF3

3.17e-05183444c6729a207526ff4aa48176207b9353176f631fea
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD55 HIVEP1 MAP4K4 AFF3

3.30e-05185444e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

DST PDLIM7 EPHA3 AFF3

3.37e-05186444e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD55 CHD7 NSD3 AFF3

3.82e-05192444ef86d82e4f04f9f54e821ef496d70fc81072d773
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

BPTF HIVEP1 WNK1 MAP4K4

3.90e-05193444e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellcontrol-Myeloid-Neutrophils_3|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD55 MAP4K4 PDLIM7 CREB5

3.90e-0519344456daf3c59a124dd068af5409113913d9ee81a454
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

MAP3K20 DST CREB5 AFF3

4.22e-051974443388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST CREB5

4.30e-05198444c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BPTF ANKRD18A TRIP11 VPS13C

4.39e-0519944461b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

BPTF TRIP11 VPS13C NSD3

4.39e-0519944418a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

CD55 BPTF TRIP11 VPS13C

4.39e-0519944453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST CREB5

4.39e-051994448d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CD55 BPTF TRIP11 VPS13C

4.39e-05199444fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST CREB5

4.39e-051994449940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CD55 PTPRH CREB5

2.93e-041314432ccf679b5035b7b9cdb9a9a660cad90288592187
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USF3 NSD3 AFF3

2.93e-04131443a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRH WNK1 ATP6V0A4

3.34e-0413744385b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MAP3K20 USF3 NSD3

3.78e-04143443bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

B3GALT2 EPHA3 AFF3

4.18e-04148443a1269312903fc27830c1835dabf660c659a711be
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZCCHC14 ZNF251 CREB5

4.88e-041564430b3630fd4479291599e1674e87eba6f93877ac3a
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHD7 NSD3 AFF3

5.25e-041604437ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

CD55 CHD7 NSD3

5.45e-0416244391ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP3K20 MAP4K4 EPHA3

5.74e-041654433d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USF3 NSD3 AFF3

5.74e-04165443fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

MAP3K20 USF3 NSD3

5.74e-04165443ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP3K20 B3GALT2 CD55

5.85e-04166443a907d39ca5cf023de633fe5f2b28759b7af4eebc
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD55 CFAP74 AFF3

5.95e-041674433c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD55 CFAP74 AFF3

5.95e-0416744328e9670586ff551b700c794313d27eedbfa1286b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

6.05e-04168443af82e07d1eec51fc6530155f37addbce6221885d
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

MAP3K20 USF3 NSD3

6.05e-04168443d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

USF3 CREBBP AFF3

6.16e-04169443c3a6179a64589a370108fea809b157839347759c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP3K20 B3GALT2 CD55

6.16e-041694431c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD55 CHD7 AFF3

6.26e-04170443070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellSevere-B_naive-11|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

VPS13C NSD3 AFF3

6.37e-041714437c2699f19ca38414447a286f7658f507882d57c2
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

6.48e-04172443bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST WNK1 MAP4K4

6.59e-04173443869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellFrontal_cortex-Macroglia|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BRICD5 MAP4K4 CREB5

6.59e-04173443ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST WNK1 MAP4K4

6.59e-041734430672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST WNK1 MAP4K4

6.59e-04173443870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

USF3 DST ZNF251

6.70e-041744432274648b80dd74f3c948a779bba3391095964c34
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

6.70e-04174443412ccc099028a372b9d953363984c2da54b2187f
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USF3 NSD3 AFF3

6.93e-04176443ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP3K20 CSRP3 CREB5

6.93e-041764439df7a124ebafb0087da0cda133a394275d7bed81
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

7.04e-04177443d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCellGlobus_pallidus-Macroglia|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BRICD5 MAP4K4 CREB5

7.27e-04179443ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCellEntopeduncular-Macroglia|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BRICD5 MAP4K4 CREB5

7.27e-04179443f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ANKRD18A ARHGAP12

7.39e-04180443e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP4K4 VPS13C CSRP3

7.51e-041814437286700396676fdc41d9723979b8b408177aceb9
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

7.51e-04181443a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

MAP3K20 USF3 NSD3

7.51e-041814430d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIVEP1 MAP4K4 AFF3

7.51e-04181443d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP3K20 DST PDLIM7

7.51e-04181443beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

MAP3K20 CSRP3 CREB5

7.63e-04182443287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

7.63e-04182443ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 DST CREB5

7.75e-04183443547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP3K20 ZNF251 PDLIM7

7.75e-04183443d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 MARCHF4 PDLIM7

7.75e-04183443e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP3K20 ZNF251 PDLIM7

7.75e-04183443e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDLIM7 CREB5 EPHA3

7.88e-041844437b5678718719020b52e7c2a7bd9797987defd7ff
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

B3GALT2 DST AFF3

7.88e-04184443d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

7.88e-04184443226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDLIM7 CREB5 EPHA3

7.88e-0418444354e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

TAB2 HIVEP1 NSD3

8.00e-04185443e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

BPTF CHD7 NSD3

8.00e-04185443857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-Naive_B_cells|GI_large-bowel / Manually curated celltypes from each tissue

CD55 MAP4K4 AFF3

8.00e-041854431c99373c123b5e0de40b47d9d885974a747b9839
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 WNK1 MAP4K4

8.00e-04185443eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIVEP1 MAP4K4 AFF3

8.13e-041864431a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIVEP1 MAP4K4 AFF3

8.13e-04186443f1366638edaecad5cad6367440f4c693513bed7e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 DST EPHA3

8.13e-041864437def03dd856b765bd3f493288641981c4f7fd26e
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 CREBBP NSD3

8.25e-04187443663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD55 CHD7 AFF3

8.38e-04188443d1bc1316bbb8cfc39acc70f8680b14d19f536997
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 PDLIM7 AFF3

8.38e-04188443b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALT2 CHD7 DST

8.38e-04188443ccd2541892112a7a303f766adf9a7afeb754498c
ToppCellIPF-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

DST PDLIM7 CREB5

8.51e-041894434178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

MAP3K20 CD55 CREB5

8.51e-04189443d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 PDLIM7 EPHA3

8.51e-04189443fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 PDLIM7 AFF3

8.51e-041894432cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellCOPD-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

MAP3K20 CD55 MAP4K4

8.51e-041894436294691231c7d38707323cf31578a107d3b2c622
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 PDLIM7 AFF3

8.51e-04189443127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DST PDLIM7 AFF3

8.64e-041904432e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 TAB2 PDLIM7

8.64e-04190443d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BPTF DST MAP4K4

8.64e-04190443d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 PDLIM7 AFF3

8.64e-0419044370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

CSRP3 CREB5 EPHA3

8.64e-04190443918ad5037881212008f9f69d5df5da91fd01422c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 TAB2 PDLIM7

8.64e-0419044371a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

HIVEP1 MAP4K4 AFF3

8.64e-041904431e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DST PDLIM7 AFF3

8.64e-041904430028f886c789ba238c031eae5d96acaed4af8c25
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAB2 TRIP11 VPS13C

8.77e-0419144360c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM7 EPHA3 AFF3

8.77e-04191443107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BPTF VPS13C AFF3

8.77e-04191443a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD55 PDLIM7 CREB5

8.77e-04191443b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM7 EPHA3 AFF3

8.77e-04191443bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAB2 TRIP11 VPS13C

8.77e-0419144309db184cb90fe282a14474d7217068c58092c6f8
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BPTF DST MAP4K4

2.56e-0450273GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
DrugCefotetan [69712-56-7]; Up 200; 7uM; HL60; HT_HG-U133A

MAP3K20 CDC5L TRIP11 PDLIM7 UBR4 NSD3

1.57e-061974261319_UP
DrugPicotamide monohydrate [80530-63-8]; Up 200; 10.2uM; HL60; HG-U133A

CFAP74 GTF3C1 EP400 PDLIM7 CIAO3 VPS13C

1.72e-062004261387_UP
DrugAnisomycin

MAP3K20 CD55 ATF2 CREBBP

1.90e-0586424ctd:D000841
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

DYNC1LI1 BPTF POGZ TRIP11 CREBBP

2.12e-051834257136_DN
DrugConvolamine hydrochloride [500-56-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

ZCCHC14 PGAP6 PDLIM7 NSD3 EPHA3

2.61e-051914252771_UP
DrugAdenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; PC3; HT_HG-U133A

B3GALT2 CD55 PTPRH PGAP6 ATP6V0A4

2.74e-051934256760_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A

CDC5L PTPRH PDLIM7 VPS13C NSD3

2.81e-051944254538_UP
Drug(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A

WNK1 PDLIM7 ATP6V0A4 EPHA3 AFF3

2.88e-051954255444_UP
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

WNK1 PGAP6 ATF2 PDLIM7 NSD3

2.95e-051964253685_DN
DrugEtodolac [41340-25-4]; Up 200; 14uM; HL60; HG-U133A

MAP3K20 SLC6A3 PGAP6 ATF2 NSD3

3.10e-051984251407_UP
Diseaseautism spectrum disorder (implicated_via_orthology)

SLC6A3 CHD7 POGZ CREBBP

6.50e-05152424DOID:0060041 (implicated_via_orthology)
DiseaseAdenocarcinoma of lung (disorder)

WNK1 CREBBP CSRP3 EPHA3

2.10e-04206424C0152013
Diseaseeosinophil percentage of granulocytes

BPTF CHD7 CSRP3 CREB5

3.41e-04234424EFO_0007996
Diseasediabetic retinopathy

TAB2 VPS13C CREB5

9.64e-04136423EFO_0003770
Diseasered blood cell density measurement

HIVEP1 DST EP400 WNK1 CSRP3 AFF3

1.45e-03880426EFO_0007978
Diseasevital capacity

CHD7 DST CDC5L TRIP11 CREB5 EPHA3 AFF3

1.66e-031236427EFO_0004312
Diseaseneutrophil-to-lymphocyte ratio

CHD7 HIVEP1 CREB5

2.33e-03185423EFO_0008447
DiseaseHuntington's disease (is_marker_for)

ATF2 CREBBP

2.60e-0353422DOID:12858 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
AVVQQPNCRTSVPSS

AFF3

396

P51826
TTNLTPVQTPARSLV

EP400

2716

Q96L91
VVQTPNTVLSTPFRT

CDC5L

401

Q99459
KTAIRIPTSNPQTSN

ANKRD18A

966

Q8IVF6
VARNAATITVTPPQS

BRICD5

86

Q6PL45
ATSLSNQVRSPAPVQ

CREBBP

2336

Q92793
RPQSLQQPATSTTET

ATF2

311

P15336
SFQPRTATVTIRPNT

BPTF

2151

Q12830
QDVVTPNSVRSQVPA

CBLL2

301

Q8N7E2
NFSSRSQTVPSPTIN

CHD7

291

Q9P2D1
SSVITQAPSTNRQIG

CREB5

141

Q02930
VVNVNPTNTRPQSDT

MAP4K4

901

O95819
QAAQAASPQVPATTT

DST

7426

Q03001
TTPNAQATRSTPVSR

CD55

321

P08174
PRTPNRSVSSNVASV

DYNC1LI1

406

Q9Y6G9
VPLSTTPRSNASVNV

PGAP6

131

Q9HCN3
TPTPLQSRTSIVQAA

PDLIM7

251

Q9NR12
SSSTEQIRATTPPNQ

ARHGAP12

221

Q8IWW6
TVPQTLRPQTATNSN

B3GALT2

86

O43825
PSSPRNVISNINETS

EPHA3

326

P29320
QITPVNQSRSSSPTQ

MAP3K20

626

Q9NYL2
RTNPRTSSSTQANIP

MARCHF4

331

Q9P2E8
QFQQSPKPARSVTTS

CSRP3

91

P50461
LSSPSQRTEVVGTQN

CFAP74

1401

Q9C0B2
AVSQNSRISPPVSTS

MROH5

21

Q6ZUA9
NSATSPRVVVTQPNT

TAB2

446

Q9NYJ8
IPATLTIRSTVPQSQ

POGZ

231

Q7Z3K3
QETPQSRPSVQVVSA

MSH4

36

O15457
NRTVTQPPLSTVQLT

REELD1

331

A0A1B0GV85
PSQQRLVVVSVSPQS

CIAO3

106

Q9H6Q4
QLTSSTLTNPRQSPV

SLC6A3

41

Q01959
SQPSPTQSVQETVRV

VPS13C

1891

Q709C8
ASFIPQVTQPSATRT

USF3

2081

Q68DE3
STPNQRNEKPTQSVS

NSD3

546

Q9BZ95
TVQSKTAPPTFNRTN

ATP6V0A4

356

Q9HBG4
TSSSARPTAQVLPVQ

ZCCHC14

466

Q8WYQ9
FSQSSQLTPPQQTRV

ZNF251

631

Q9BRH9
TPLRPNQQSVVNSSF

TRIP11

1846

Q15643
FLQVTPPTSQNTTAR

ZNF280C

536

Q8ND82
TATATSQVAQQPPAA

WNK1

126

Q9H4A3
NSSTANRVKTSQPPV

GTF3C1

716

Q12789
QLTSVFNPRTVASQP

UBR4

196

Q5T4S7
FNPRTVASQPISTQT

UBR4

201

Q5T4S7
VTSATAPNPVRNLTV

PTPRH

291

Q9HD43
LTSPSSRSQVTPQNQ

HIVEP1

336

P15822