Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-glutamic acid ligase activity	TTLL2 TTLL11 TTLL4	5.75e-06	10	74	3	GO:0070739
GeneOntologyMolecularFunction	tubulin-glutamic acid ligase activity	TTLL2 TTLL11 TTLL4	5.75e-06	10	74	3	GO:0070740
GeneOntologyMolecularFunction	acid-amino acid ligase activity	TTLL2 TTLL11 TTLL4	8.20e-05	23	74	3	GO:0016881
GeneOntologyMolecularFunction	Fc-gamma receptor I complex binding	IGHG2 IGHG4	2.81e-04	7	74	2	GO:0034988
GeneOntologyBiologicalProcess	protein polyglutamylation	TTLL2 TTLL11 TTLL4	1.45e-05	13	78	3	GO:0018095
GeneOntologyBiologicalProcess	immunoglobulin production	VPREB1 IGHG2 IGHG4 IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	3.56e-05	241	78	7	GO:0002377
GeneOntologyCellularComponent	immunoglobulin complex	IGHG2 IGHG4 IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	3.94e-05	166	79	6	GO:0019814
Domain	TTL	TTLL2 TTLL11 TTLL4	1.59e-05	13	73	3	PS51221
Domain	TTL/TTLL_fam	TTLL2 TTLL11 TTLL4	1.59e-05	13	73	3	IPR004344
Domain	TTL	TTLL2 TTLL11 TTLL4	1.59e-05	13	73	3	PF03133
Domain	LRR_6	NLRP9 FBXL16 NLRC5 LRRC71	6.30e-05	55	73	4	PF13516
Domain	NACHT	NLRP9 NLRC5 TEP1	9.59e-05	23	73	3	PS50837
Domain	NACHT_NTPase	NLRP9 NLRC5 TEP1	9.59e-05	23	73	3	IPR007111
Domain	uDENN	DENND1C MADD	1.33e-03	14	73	2	SM00800
Domain	-	MKKS BBS12	1.33e-03	14	73	2	1.10.560.10
Domain	GROEL-like_equatorial	MKKS BBS12	1.33e-03	14	73	2	IPR027413
Domain	Cpn60/TCP-1	MKKS BBS12	1.53e-03	15	73	2	IPR002423
Domain	Cpn60_TCP1	MKKS BBS12	1.53e-03	15	73	2	PF00118
Domain	-	MKKS BBS12	1.53e-03	15	73	2	3.50.7.10
Domain	uDENN	DENND1C MADD	1.53e-03	15	73	2	PF03456
Domain	GroEL-like_apical_dom	MKKS BBS12	1.53e-03	15	73	2	IPR027409
Domain	-	NLRP9 FBXL16 LINGO4 NLRC5 PRAMEF12 LRRC71	1.59e-03	321	73	6	3.80.10.10
Domain	UDENN	DENND1C MADD	1.75e-03	16	73	2	PS50946
Domain	DDENN	DENND1C MADD	1.75e-03	16	73	2	PS50947
Domain	DENN	DENND1C MADD	1.75e-03	16	73	2	SM00799
Domain	dDENN	DENND1C MADD	1.75e-03	16	73	2	SM00801
Domain	DENN	DENND1C MADD	1.75e-03	16	73	2	PF02141
Domain	dDENN_dom	DENND1C MADD	1.75e-03	16	73	2	IPR005112
Domain	uDENN_dom	DENND1C MADD	1.75e-03	16	73	2	IPR005113
Domain	dDENN	DENND1C MADD	1.75e-03	16	73	2	PF03455
Domain	DENN	DENND1C MADD	1.75e-03	16	73	2	PS50211
Domain	DENN_dom	DENND1C MADD	1.75e-03	16	73	2	IPR001194
Domain	L_dom-like	NLRP9 FBXL16 LINGO4 NLRC5 PRAMEF12 LRRC71	1.78e-03	328	73	6	IPR032675
Domain	Leu-rich_rpt_Cys-con_subtyp	FBXL16 NLRC5	2.47e-03	19	73	2	IPR006553
Domain	LRR_CC	FBXL16 NLRC5	2.47e-03	19	73	2	SM00367
Domain	Leu-rich_rpt	NLRP9 FBXL16 LINGO4 NLRC5 LRRC71	4.17e-03	271	73	5	IPR001611
Domain	RA	RALGDS MYO9A	6.51e-03	31	73	2	SM00314
Domain	ATP_grasp_subdomain_2	TTLL2 TTLL4	6.51e-03	31	73	2	IPR013816
Pubmed	Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing.	BRCA2 IGHG2 IGHG4	2.24e-07	6	79	3	27769169
Pubmed	AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling.	IGHG2 IGHG4 ARHGEF6	6.27e-07	8	79	3	18378701
Pubmed	Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.	FOXN2 RELN CXCR4 MCM5 SPAG5	2.63e-06	95	79	5	21440680
Pubmed	Activation of C1r by proteolytic cleavage.	IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	2.84e-06	43	79	4	1249422
Pubmed	A targeted multienzyme mechanism for selective microtubule polyglutamylation.	TTLL2 TTLL11 TTLL4	3.17e-06	13	79	3	17499049
Pubmed	Physicochemical and functional characterization of the C1r subunit of the first complement component.	IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	4.08e-06	47	79	4	814163
Pubmed	Recognition of immunoglobulins by Fcgamma receptors.	IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	4.45e-06	48	79	4	11955599
Pubmed	A novel H395R mutation in MKKS/BBS6 causes retinitis pigmentosa and polydactyly without other findings of Bardet-Biedl or McKusick-Kaufman syndrome.	MKKS BBS12	5.09e-06	2	79	2	26900326
Pubmed	Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer.	THBS1 SKI	5.09e-06	2	79	2	21107877
Pubmed	One-megabase sequence analysis of the human immunoglobulin lambda gene locus.	VPREB1 IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	5.17e-06	109	79	5	9074928
Pubmed	Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair.	THBS1 RELN	1.53e-05	3	79	2	38147128
Pubmed	Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer.	THBS1 CXCR4	1.53e-05	3	79	2	30254632
Pubmed	Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.	RELN CXCR4	1.53e-05	3	79	2	15013630
Pubmed	Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains.	IGHG2 IGHG4	3.05e-05	4	79	2	6283537
Pubmed	Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain.	IGHG2 IGHG4	3.05e-05	4	79	2	6801765
Pubmed	Sequence analysis of cloned cDNA encoding part of an immunoglobulin heavy chain.	IGHG2 IGHG4	3.05e-05	4	79	2	113776
Pubmed	Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.	IGHG2 IGHG4	3.05e-05	4	79	2	11812141
Pubmed	Multiple amino acid substitutions between murine gamma 2a heavy chain Fc regions of Ig1a and Ig1b allotypic forms.	IGHG2 IGHG4	3.05e-05	4	79	2	6794027
Pubmed	Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response.	IGHG2 IGHG4	3.05e-05	4	79	2	6306571
Pubmed	Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes.	IGHG2 IGHG4	3.05e-05	4	79	2	2510996
Pubmed	Spontaneous deletions in Ig heavy chain genes: flanking sequences influence splice site selection.	IGHG2 IGHG4	3.05e-05	4	79	2	1754385
Pubmed	Sialic acid residues are essential for the anaphylactic activity of murine IgG1 antibodies.	IGHG2 IGHG4	3.05e-05	4	79	2	19050247
Pubmed	Mutations in chaperonin-like BBS genes are a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population.	MKKS BBS12	3.05e-05	4	79	2	20472660
Pubmed	The molecular and biochemical characterization of mutant monoclonal antibodies with increased antigen binding.	IGHG2 IGHG4	3.05e-05	4	79	2	1672339
Pubmed	Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin.	IGHG2 IGHG4	3.05e-05	4	79	2	6407005
Pubmed	An autoimmune disease variant of IgG1 modulates B cell activation and differentiation.	IGHG2 IGHG4	3.05e-05	4	79	2	30287618
Pubmed	Switch transcripts in immunoglobulin class switching.	IGHG2 IGHG4	3.05e-05	4	79	2	7892607
Pubmed	Determination of the primary structure of a mouse G2a immunoglobulin. Identification of the disulfide bridges.	IGHG2 IGHG4	3.05e-05	4	79	2	4565406
Pubmed	Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.	IGHG2 IGHG4	3.05e-05	4	79	2	1713710
Pubmed	Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA.	IGHG2 IGHG4	3.05e-05	4	79	2	6777755
Pubmed	The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses.	IGHG2 IGHG4	3.05e-05	4	79	2	9103199
Pubmed	Gene conversion and polymorphism: generation of mouse immunoglobulin gamma 2a chain alleles by differential gene conversion by gamma 2b chain gene.	IGHG2 IGHG4	3.05e-05	4	79	2	6297797
Pubmed	Evolution of immunoglobulin subclasses. Primary structure of a murine myeloma gamma1 chain.	IGHG2 IGHG4	3.05e-05	4	79	2	98524
Pubmed	IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.	IGHG2 IGHG4	3.05e-05	4	79	2	25363774
Pubmed	Mutational deglycosylation of the Fc portion of immunoglobulin G causes O-sulfation of tyrosine adjacently preceding the originally glycosylated site.	IGHG2 IGHG4	3.05e-05	4	79	2	20621099
Pubmed	Immunoglobulin heavy constant gamma 1 silencing decreases tonicity-responsive enhancer-binding protein expression to alleviate diabetic nephropathy.	IGHG2 IGHG4	3.05e-05	4	79	2	38268239
Pubmed	Antibody epitopes on the neuraminidase of a recent H3N2 influenza virus (A/Memphis/31/98).	IGHG2 IGHG4	3.05e-05	4	79	2	12414967
Pubmed	Gene segments encoding transmembrane carboxyl termini of immunoglobulin gamma chains.	IGHG2 IGHG4	3.05e-05	4	79	2	6799207
Pubmed	Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family.	IGHG2 IGHG4	3.05e-05	4	79	2	6787604
Pubmed	Shutdown of class switch recombination by deletion of a switch region control element.	IGHG2 IGHG4	3.05e-05	4	79	2	8438159
Pubmed	Passive anaphylaxis in mice with gamma-G antibodies. V. Competitive effects of different immunoglobulins and inhibition of reactions with antiglobulin sera.	IGHG2 IGHG4	3.05e-05	4	79	2	4098598
Pubmed	Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-gamma 2a heavy chain.	IGHG2 IGHG4	3.05e-05	4	79	2	6253932
Pubmed	Immunoglobulin gamma 1 heavy chain gene: structural gene sequences cloned in a bacterial plasmid.	IGHG2 IGHG4	3.05e-05	4	79	2	6769752
Pubmed	Mouse immunoglobulin allotypes: post-duplication divergence of gamma 2a and gamma 2b chain genes.	IGHG2 IGHG4	3.05e-05	4	79	2	6803173
Pubmed	Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.	IGHG2 IGHG4	3.05e-05	4	79	2	6170065
Pubmed	Linkage of the four gamma subclass heavy chain genes.	IGHG2 IGHG4	3.05e-05	4	79	2	6264445
Pubmed	Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals.	IGHG2 IGHG4	3.05e-05	4	79	2	19703988
Pubmed	Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1.	TTLL2 TTLL4	3.05e-05	4	79	2	11054573
Pubmed	ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.	OSBPL10 APOB	3.05e-05	4	79	2	22906437
Pubmed	Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.	IGHG2 IGHG4	3.05e-05	4	79	2	2878362
Pubmed	IgG1 deficiency exacerbates experimental autoimmune myasthenia gravis in BALB/c mice.	IGHG2 IGHG4	3.05e-05	4	79	2	25867470
Pubmed	Sequence of the gamma 2b membrane 3' untranslated region: polya site determination and comparison to the gamma 2a membrane 3' untranslated region.	IGHG2 IGHG4	3.05e-05	4	79	2	1542303
Pubmed	Switch of CD4+ T cell differentiation from Th2 to Th1 by treatment with cathepsin B inhibitor in experimental leishmaniasis.	IGHG2 IGHG4	3.05e-05	4	79	2	9725203
Pubmed	Nucleotide sequences of all the gamma gene loci of murine immunoglobulin heavy chains.	IGHG2 IGHG4	3.05e-05	4	79	2	9126488
Pubmed	Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.	IGHG2 IGHG4	3.05e-05	4	79	2	6767246
Pubmed	Determination of the interface of a large protein complex by transferred cross-saturation measurements.	IGHG2 IGHG4	3.05e-05	4	79	2	12051834
Pubmed	The gamma 1 heavy chain gene includes all of the cis-acting elements necessary for expression of properly regulated germ-line transcripts.	IGHG2 IGHG4	3.05e-05	4	79	2	8683112
Pubmed	The IL-4 induced increase in the frequency of resting murine splenic B cells expressing germline Ig heavy chain gamma 1 transcripts correlates with subsequent switching to IgG1.	IGHG2 IGHG4	3.05e-05	4	79	2	8452816
Pubmed	Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.	IGHG2 IGHG4	3.05e-05	4	79	2	807855
Pubmed	Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse.	IGHG2 IGHG4	3.05e-05	4	79	2	4166666
Pubmed	Multiple B-cell epitope vaccine induces a Staphylococcus enterotoxin B-specific IgG1 protective response against MRSA infection.	IGHG2 IGHG4	3.05e-05	4	79	2	26201558
Pubmed	Nucleotide sequence of a human immunoglobulin C gamma 4 gene.	IGHG2 IGHG4	3.05e-05	4	79	2	6299662
Pubmed	Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling.	RELN CXCR4	3.05e-05	4	79	2	16964252
Pubmed	Molecular cloning of mouse immunoglobulin heavy chain messenger ribonucleic acids coding for mu, alpha, gamma 1, gamma 2a, and gamma 3 chains.	IGHG2 IGHG4	3.05e-05	4	79	2	6249338
Pubmed	Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes.	IGHG2 IGHG4	3.05e-05	4	79	2	6804948
Pubmed	mRNA for surface immunoglobulin gamma chains encodes a highly conserved transmembrane sequence and a 28-residue intracellular domain.	IGHG2 IGHG4	3.05e-05	4	79	2	6804950
Pubmed	Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.	IGHG2 IGHG4	3.05e-05	4	79	2	19592272
Pubmed	Attenuation of Trypanosoma brucei is associated with reduced immunosuppression and concomitant production of Th2 lymphokines.	IGHG2 IGHG4	3.05e-05	4	79	2	10720538
Pubmed	Determination of the primary structure of a mouse IgG2a immunoglobulin:amino-acid sequence of the Fc fragment. Implications for the evolution of immunoglobulin structure and function.	IGHG2 IGHG4	3.05e-05	4	79	2	4831970
Pubmed	Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin gamma 2b-chain gene.	IGHG2 IGHG4	3.05e-05	4	79	2	7439686
Pubmed	Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.	IGHG2 IGHG4	3.05e-05	4	79	2	24752300
Pubmed	Variable-region-identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype.	IGHG2 IGHG4	3.05e-05	4	79	2	15699144
Pubmed	On immunoglobulin heavy chain gene switching: two gamma 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed.	IGHG2 IGHG4	3.05e-05	4	79	2	6278424
Pubmed	An Asia-specific variant of human IgG1 represses colorectal tumorigenesis by shaping the tumor microenvironment.	IGHG2 IGHG4	3.05e-05	4	79	2	35133976
Pubmed	Restriction fragment length polymorphism and evolution of the mouse immunoglobulin constant region gamma loci.	IGHG2 IGHG4	3.05e-05	4	79	2	8099342
Pubmed	Sequence and polyadenylation site determination of the murine immunoglobulin gamma 2a membrane 3' untranslated region.	IGHG2 IGHG4	3.05e-05	4	79	2	2513486
Pubmed	Increased number of T cells and exacerbated inflammatory pathophysiology in a human IgG4 knock-in MRL/lpr mouse model.	IGHG2 IGHG4	3.05e-05	4	79	2	36763580
Pubmed	Ubiquitination of IgG1 cytoplasmic tail modulates B-cell signalling and activation.	IGHG2 IGHG4	3.05e-05	4	79	2	32006024
Pubmed	Strong antigenic selection shaping the immunoglobulin heavy chain repertoire of B-1a lymphocytes in lambda 2(315) transgenic mice.	IGHG2 IGHG4	3.05e-05	4	79	2	12209645
Pubmed	Independent immunoglobulin class-switch events occurring in a single myeloma cell line.	IGHG2 IGHG4	3.05e-05	4	79	2	3921826
Pubmed	Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain.	IGHG2 IGHG4	3.05e-05	4	79	2	117549
Pubmed	Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination.	IGHG2 IGHG4	3.05e-05	4	79	2	116231
Pubmed	The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer.	IGHG2 IGHG4	3.05e-05	4	79	2	6262729
Pubmed	Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.	IGHG2 IGHG4	3.05e-05	4	79	2	26683050
Pubmed	Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a.	IGHG2 IGHG4	3.05e-05	4	79	2	25451975
Pubmed	Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA.	IGHG2 IGHG4	3.05e-05	4	79	2	6766534
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CLCNKA RSL1D1 C5orf63 TTLL4 NFX1 PRAMEF12 APOB ARHGEF6 SPAG5 MADD LRRC71	3.34e-05	1084	79	11	11544199
Pubmed	Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma.	IGHG2 IGHG4	5.07e-05	5	79	2	35044826
Pubmed	Exon shuffling generates an immunoglobulin heavy chain gene.	IGHG2 IGHG4	5.07e-05	5	79	2	6769120
Pubmed	Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.	IGHG2 IGHG4	5.07e-05	5	79	2	6770027
Pubmed	Sequential class switching is required for the generation of high affinity IgE antibodies.	IGHG2 IGHG4	5.07e-05	5	79	2	22249450
Pubmed	Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences.	IGHG2 IGHG4	5.07e-05	5	79	2	6421489
Pubmed	The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.	IGHG2 IGHG4	5.07e-05	5	79	2	26620759
Pubmed	Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice.	IGHG2 IGHG4	5.07e-05	5	79	2	32640012
Pubmed	Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies.	IGHG2 IGHG4	5.07e-05	5	79	2	7704573
Pubmed	Channel catfish soluble FcmuR binds conserved linear epitopes present on Cmu3 and Cmu4.	IGHG2 IGHG4	5.07e-05	5	79	2	20031218
Pubmed	Human and murine immunoglobulin expression vector cassettes.	IGHG2 IGHG4	5.07e-05	5	79	2	11257305
Pubmed	Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.	IGHG2 IGHG4	5.07e-05	5	79	2	32229726
Pubmed	Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons.	RELN CXCR4	5.07e-05	5	79	2	18272682
Pubmed	Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation.	IGHG2 IGHG4	5.07e-05	5	79	2	34539636
Cytoband	22q11.2	IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	5.73e-05	120	79	4	22q11.2
GeneFamily	Tubulin tyrosine ligase family	TTLL2 TTLL11 TTLL4	9.47e-06	14	55	3	779
GeneFamily	Immunoglobulin lambda locus at 22q11.2	IGLV10-54 IGLV4-69 IGLV4-60 IGLV4-3	1.54e-04	89	55	4	353
GeneFamily	Chaperonins	MKKS BBS12	9.30e-04	15	55	2	587
GeneFamily	Bardet-Biedl syndrome associated\|BBSome	MKKS BBS12	1.84e-03	21	55	2	980
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND1C MADD	2.61e-03	25	55	2	504
GeneFamily	NLR family	NLRP9 NLRC5	2.61e-03	25	55	2	666
ToppCell	Influenza_Severe-B_memory\|World / Disease group and Cell class	VPREB1 IGHG2 IGHG4 OSBPL10 IGLV4-69 TMEM269	4.44e-07	162	79	6	21eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDR2 CLCNKA MYO9A KIF21A OSBPL10 TFAP2B	1.13e-06	190	79	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDR2 CLCNKA MYO9A KIF21A OSBPL10 TFAP2B	1.13e-06	190	79	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	PCW_10-12-Immune_Lymphocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT72 VPREB1 CXCR4 DENND1C ZNF831 KLRC2	1.13e-06	190	79	6	9b56763d62e1ed50006a5b90b160c5a82aab515b
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH6 VPREB1 LINGO4 NLRC5 KLRC2	8.09e-06	154	79	5	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts\|(1)_Control_(PBS) / Stress and Cell class	CDR2 THBS1 CXCR4 KIF21A MCM5	9.74e-06	160	79	5	8450466fc2465c56798df2b520edd23c2c2e941c
ToppCell	Influenza_Severe-B_memory\|Influenza_Severe / Disease group and Cell class	IGHG2 IGHG4 OSBPL10 IGLV4-69 TMEM269	1.13e-05	165	79	5	51172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT72 CXCR4 DENND1C ZNF831 KLRC2	1.23e-05	168	79	5	318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT72 CXCR4 DENND1C ZNF831 KLRC2	1.23e-05	168	79	5	75b3998aff704a77895ee3723813d8a3819b7cec
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	DCAF1 TRAPPC13 MYO9A OSBPL10 ARHGEF6	1.42e-05	173	79	5	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CXCR4 IGHG2 NLRC5 DENND1C ZNF831	1.46e-05	174	79	5	1b2a2129c08bac01fc638692313b196759a1e0d7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CXCR4 IGHG2 NLRC5 DENND1C ZNF831	1.46e-05	174	79	5	5bde24eb588dc588efc413811379548120ec0c7f
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	VPREB1 IGHG2 IGHG4 IGLV4-69 IGLV4-60	1.54e-05	176	79	5	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	Control-B_cells\|Control / group, cell type (main and fine annotations)	TSBP1 CXCR4 IGHG2 IGHG4 OSBPL10	1.54e-05	176	79	5	9125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPREB1 CXCR4 IGLV10-54 IGLV4-69 IGLV4-3	1.63e-05	178	79	5	34ef4d36ddfb1cdeaaaf5d952e1ad6dc2785ce1e
ToppCell	Children_(3_yrs)-Immune-B_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TSBP1 IGHG2 IGHG4 OSBPL10 IGLV10-54	1.67e-05	179	79	5	31411780f1a44bf2d102f288416e97eacec4b6b6
ToppCell	Adult-Immune-T_lymphocyte-D122\|Adult / Lineage, Cell type, age group and donor	CXCR4 NLRC5 PCNX1 ZNF831 KLRC2	1.72e-05	180	79	5	06c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell	droplet-Spleen-nan-21m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 RELN TTLL4 BBS12	1.92e-05	89	79	4	e7d9498a1a3aa974fdd68b394c3eaff8e35c9727
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT72 CXCR4 DENND1C ZNF831 KLRC2	2.07e-05	187	79	5	b5c8322ee728303425be677aa0c36fa552fd0f59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDR2 CLCNKA MYO9A KIF21A OSBPL10	2.07e-05	187	79	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT72 CXCR4 DENND1C ZNF831 KLRC2	2.12e-05	188	79	5	624426815b789f0f35c327b8c3c0c05ba3aa7d98
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CLCNKA NINL TFAP2B SPAG5	2.12e-05	188	79	5	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CLCNKA NINL TFAP2B SPAG5	2.17e-05	189	79	5	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KRT72 LINGO4 FSD1 ZNF831 KLRC2	2.23e-05	190	79	5	67fa7472ec534179087963177351552cc3c335eb
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KRT72 LINGO4 FSD1 ZNF831 KLRC2	2.23e-05	190	79	5	094efcde2b037ae509298abb8b2b1d52f9c86a45
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-pre-B-I_cell\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VPREB1 CXCR4 NLRC5 IGLV10-54 IGLV4-69	2.29e-05	191	79	5	146edd214aac49f9b910bb982e3d77a052c8b316
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.38e-05	94	79	4	4b6623de5a517ebf5df865e0dcd615111622ad3e
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	FOXN2 GNL3L USP38 KIF21A PCNX1	2.40e-05	193	79	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GNL3L FBXL16 TTLL11 PGM2L1 MADD	2.46e-05	194	79	5	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CXCR4 ABCB5 LINGO4 PCNX1 FSD1	2.52e-05	195	79	5	d70b49f6b9c6c4422adb2936c837a1af7569fb0a
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CXCR4 IGHG2 IGLV10-54 IGLV4-69 TREML2	2.65e-05	197	79	5	0e56255862fed099e771ebd2529393dc5a3641ba
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CXCR4 IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.65e-05	197	79	5	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	severe\|World / disease stage, cell group and cell class	THBS1 CXCR4 IGHG2 IGHG4 IGLV4-69	2.65e-05	197	79	5	db7367210b5480b53002407f3e66988e85a5c22f
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CXCR4 IGHG2 IGLV4-69 IGLV4-60 IGLV4-3	2.72e-05	198	79	5	d51ee880acc5804cd918105fac846a1528333d6c
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-B-B_memory\|ICU-NoSEP / Disease, condition lineage and cell class	CXCR4 IGHG2 IGHG4 OSBPL10 IGLV10-54	2.78e-05	199	79	5	acd2b87ab0d7d92515cf46ab65b766d6ade818a6
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CXCR4 NLRC5 DENND1C ZNF831 KLRC2	2.85e-05	200	79	5	5f41906cf1585e09b150a84364d47c3e466dc5b7
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CXCR4 NLRC5 DENND1C ZNF831 KLRC2	2.85e-05	200	79	5	13d8c5d65d7f900979319433e7044efa6d06de20
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELN BRCA2 MCM5 DENND1C	1.07e-04	138	79	4	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	USP31 USP38 NINL ZNF831	1.10e-04	139	79	4	7c02caed5b9baf233bd6fb9a453708b3e157c790
ToppCell	metastatic_Lymph_Node-B_lymphocytes-Plasma_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IGHG2 IGHG4 IGLV10-54 IGLV4-60	1.19e-04	142	79	4	5ba3a33c2ee20be8baaed97536ca6e9d1de6752f
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|390C / Donor, Lineage, Cell class and subclass (all cells)	CXCR4 ARID2 TTLL4 KLRC2	1.22e-04	143	79	4	d877d914e4e74db2053baa310d318d6440e672bc
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	THBS1 RELN ADGRE3 PCNX1	1.54e-04	152	79	4	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1B DENND1C ZNF831 LRRC71	1.75e-04	157	79	4	cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1B DENND1C ZNF831 LRRC71	1.75e-04	157	79	4	16581e2399a211633f870dce326c75ff4b6a5fe6
ToppCell	Fetal_29-31_weeks-Immune-mast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CXCR4 ABCB5 LINGO4 ARHGEF6	1.79e-04	158	79	4	0c27c475289c70b17b6a66fc71f628511c5f0ae1
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LIPT1 HUS1B NLRC5 PAPOLG	1.88e-04	160	79	4	8aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CXCR4 IGHG2 IGHG4	1.97e-04	162	79	4	ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NINL DENND1C TEP1 ARHGEF6	1.97e-04	162	79	4	388670cf3acef17df971c0d8ae3ce14398945192
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KCNH6 HUS1B CXCR4 NLRC5	1.97e-04	162	79	4	4b9f80f701dcbb2508f497095cb8a7a2ca51cb5e
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CXCR4 IGHG2 IGHG4	1.97e-04	162	79	4	9e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCell	367C-Lymphocytic-ILC-ILC-1\|367C / Donor, Lineage, Cell class and subclass (all cells)	CXCR4 C5orf63 NINL KLRC2	1.97e-04	162	79	4	74cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CXCR4 KIF21A LINGO4 KLRC2	1.97e-04	162	79	4	3b89c3758835b7b9f9d4fb0bc8ed06da382fe48b
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NINL DENND1C TEP1 ARHGEF6	1.97e-04	162	79	4	9333d923225df7bfdf6b3a4c32816751315aec50
ToppCell	Healthy_Control-Lymphoid-Plasma\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	LDB1 IGHG2 IGHG4 IGLV4-69	2.02e-04	163	79	4	2913ccdd4613472cd82077d4993e1d9f8b223398
ToppCell	Adult-Immune-B_cell-D231\|Adult / Lineage, Cell type, age group and donor	CXCR4 IGHG4 OSBPL10 DIPK1B	2.02e-04	163	79	4	4f5821299b265663c7d0352b28285f56e1988841
ToppCell	Healthy_Control-Lymphoid-Plasma-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	LDB1 IGHG2 IGHG4 IGLV4-69	2.02e-04	163	79	4	b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	DCAF1 TRAPPC13 CXCR4 ARHGEF6	2.21e-04	167	79	4	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.21e-04	167	79	4	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.21e-04	167	79	4	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	IIH-naiveBc\|IIH / Condition, Cell_class and T cell subcluster	VPREB1 IGHG2 IGHG4 OSBPL10	2.27e-04	168	79	4	8450ed6720d308c711dfbc76652e5821be7b8e93
ToppCell	IIH-naiveBc-\|IIH / Condition, Cell_class and T cell subcluster	VPREB1 IGHG2 IGHG4 OSBPL10	2.27e-04	168	79	4	27b500f79aedc4669988670c92ff1a47dcbdf2a0
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.32e-04	169	79	4	0c2384f780ec25710ebb35c0b0df8f4afb53c9b1
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells\|B_lymphocytes / Location, Cell class and cell subclass	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.32e-04	169	79	4	150c08c7b1dc0f46173a7b8f6a3fc70d82906c0d
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CXCR4 IGHG4 OSBPL10 NLRC5	2.37e-04	170	79	4	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	Bac-SEP-Lymphocyte-B-B_memory\|Bac-SEP / Disease, Lineage and Cell Type	CXCR4 IGHG2 IGHG4 OSBPL10	2.37e-04	170	79	4	86db153984437ef1447eae8ef30a40be0925ffd5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHG2 IGHG4 IGLV4-69 SPAG5	2.42e-04	171	79	4	13126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCell	ICU-SEP-Lymphocyte-B-B_intermediate\|ICU-SEP / Disease, Lineage and Cell Type	IGHG2 IGHG4 OSBPL10 IGLV4-60	2.42e-04	171	79	4	2e44bf6f3d90193e7cadcac48bb852bd632a81bc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM5 SLC43A3 ARHGEF6 TREML2	2.42e-04	171	79	4	c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ABCB5 LINGO4 FSD1 KLRC2	2.48e-04	172	79	4	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPREB1 CXCR4 PGM2L1 ZNF831	2.53e-04	173	79	4	b367b62309389e8b6a65de83c2434dc8ec905985
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP38 CXCR4 ARHGAP33 TREML2	2.53e-04	173	79	4	49030c2dd04b592655df1a667e2f90efb499e0a5
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP38 CXCR4 ARHGAP33 TREML2	2.53e-04	173	79	4	1cfbab6603f8baf8e238837bb72740c43a7dc0ec
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHG2 IGHG4 IGLV4-60 IGLV4-3	2.53e-04	173	79	4	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	Influenza_Severe-B_intermediate\|Influenza_Severe / Disease group and Cell class	IGHG2 IGHG4 C5orf63 OSBPL10	2.59e-04	174	79	4	4276bdaac53aebd3084323a90ecde572d3177446
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL4 BBS12 ARHGEF6 MADD	2.59e-04	174	79	4	ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VPREB1 CXCR4 IGLV4-69 IGLV4-60	2.59e-04	174	79	4	183ff6b93b7fbe43d83e12427e234bd7d8745961
ToppCell	(5)_Plasma-(5)_Plasma_IgG\|(5)_Plasma / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CXCR4 IGHG2 IGHG4	2.62e-04	70	79	3	bfe020c111a27337ed4dc6ee59b74bc36b03eb49
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	KCNH6 HUS1B CXCR4 NLRC5	2.70e-04	176	79	4	9399e174d14e81cc977fcb48facf844ee6726603
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCR4 ABCB5 LINGO4 FSD1	2.70e-04	176	79	4	238244294d08975df6bfa26b2b437db3654408ae
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.76e-04	177	79	4	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.76e-04	177	79	4	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.76e-04	177	79	4	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE3A KIF21A MCM5 SLC43A3	2.76e-04	177	79	4	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.82e-04	178	79	4	9e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.82e-04	178	79	4	aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS1 TTLL11 PGM2L1 TREML2	2.82e-04	178	79	4	bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPREB1 CXCR4 NLRC5 ZNF831	2.88e-04	179	79	4	223f0895da89c7606f637aef113912dd06f39c5a
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHG2 IGHG4 IGLV10-54 IGLV4-60	2.88e-04	179	79	4	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNH6 PDE3A ABCB5 LINGO4	2.88e-04	179	79	4	5bf191bdc0c32bce83ab5c38f0616e209e420e55
ToppCell	IPF-Lymphoid-ILC_B\|IPF / Disease state, Lineage and Cell class	VPREB1 CXCR4 ABCB5 LINGO4	2.95e-04	180	79	4	b2fde7cd140a3ede8cac2d06f1f72eb438def82e
ToppCell	IPF-Lymphoid-ILC_B\|World / Disease state, Lineage and Cell class	VPREB1 CXCR4 ABCB5 LINGO4	2.95e-04	180	79	4	a4de9f67a7ab4b3c17247139fc584e13678411b4
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHG2 IGHG4 IGLV4-69 IGLV4-60	2.95e-04	180	79	4	cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCell	normal_Lymph_Node-B_lymphocytes-Plasma_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	IGHG2 IGHG4 IGLV4-69 IGLV4-60	3.01e-04	181	79	4	949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCell	Control-Lymphoid-B\|World / Disease state, Lineage and Cell class	CXCR4 IGHG2 IGHG4 OSBPL10	3.01e-04	181	79	4	9124f1a610cfc3355ad87921cd3eb5346956475d
ToppCell	Control-Classical_Monocyte-cMono_4\|Control / Disease condition and Cell class	RALGDS CXCR4 PCNX1 SKI	3.01e-04	181	79	4	f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1B MCM5 KLRC2 SPAG5	3.07e-04	182	79	4	0370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CXCR4 IGHG2 IGHG4 OSBPL10	3.07e-04	182	79	4	5f1f10c845b73d1f69794277925ef847ff23ac2d
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPREB1 ABCB5 LINGO4 FSD1	3.07e-04	182	79	4	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	URO-Lymphocyte-B-B_memory\|URO / Disease, Lineage and Cell Type	CXCR4 IGHG2 IGHG4 OSBPL10	3.07e-04	182	79	4	8ffdf15230349ad53fe15bb467724d28c5a05bf6
ToppCell	Leuk-UTI-Lymphocyte-B-B_memory\|Leuk-UTI / Disease, Lineage and Cell Type	CXCR4 IGHG2 IGHG4 OSBPL10	3.14e-04	183	79	4	f7a5daec3e8484c7071164a09e9c961fe64d9f81
Disease	immunoglobulin G measurement	IGHG2 IGHG4	6.04e-06	2	73	2	EFO_0020465
Disease	prostate cancer (biomarker_via_orthology)	THBS1 BRCA2	3.61e-05	4	73	2	DOID:10283 (biomarker_via_orthology)
Disease	immunoglobulin isotype switching measurement	IGHG2 KLRC2 PAPOLG	1.79e-04	44	73	3	EFO_0010128
Disease	triglycerides to total lipids in large HDL percentage	NLRC5 APOB MADD	4.49e-04	60	73	3	EFO_0022330
Disease	total lipids in very large HDL measurement	NLRC5 APOB MADD	5.94e-04	66	73	3	EFO_0022312
Disease	phospholipids in very large HDL measurement	NLRC5 APOB MADD	5.94e-04	66	73	3	EFO_0022298
Disease	cholesterol in very large HDL measurement	NLRC5 APOB MADD	6.77e-04	69	73	3	EFO_0022229
Disease	Bardet-Biedl syndrome 1 (disorder)	MKKS BBS12	8.02e-04	17	73	2	C2936862
Disease	Bardet-Biedl syndrome	MKKS BBS12	9.00e-04	18	73	2	cv:C0752166
Disease	free cholesterol in large HDL measurement	NLRC5 APOB MADD	1.00e-03	79	73	3	EFO_0022157
Disease	HMG CoA reductase inhibitor use measurement	BRCA2 PCNX1 APOB SKI	1.26e-03	189	73	4	EFO_0009932
Disease	mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement	FOXN2 TSBP1 TTLL11 DIPK1B BBS12	1.33e-03	328	73	5	EFO_0008377, EFO_0008378
Disease	Agents acting on the renin-angiotensin system use measurement	CEP68 USP38 PCNX1 ZNF831 TFAP2B	1.46e-03	335	73	5	EFO_0009931
Disease	periodontitis	TSBP1 TTLL11 OSBPL10 IGLV4-60	2.30e-03	223	73	4	EFO_0000649

Protein segments in the cluster

Peptide	Gene	Start	Entry
RNCSASKTTLPVLTL	C5orf63	21	A6NC05
GRLSTSSCASVSRNK	nan	121	Q6ZR03
LIRGPASCSSLSKTS	ARHGEF6	546	Q15052
ALTSVSRGSSLKILS	CXCR4	316	P61073
SCLSSSLLINKAGNV	CATSPERB	621	Q9H7T0
GTAARSNLTSLKSSL	CEP68	651	Q76N32
SSGCGKSTSVQLLQR	ABCB5	1051	Q2M3G0
STCSKLARGGILTST	ARID2	551	Q68CP9
TASKLCSALTLSGLV	CIAPIN1	111	Q6FI81
TQLRTCTTLSGLASQ	DIPK1B	391	Q5VUD6
RVLLTASKLSTLTSC	DENND1C	216	Q8IV53
NTSRTLKNSLLADTC	BBS12	211	Q6ZW61
CSVPGRLSLLSSTSK	TFAP2B	231	Q92481
SASLGASVKLTCTLS	IGLV4-69	31	A0A075B6H9
ALACKALVGLSRSST	DCAF1	756	Q9Y4B6
STALKVALFCTTLSG	MKKS	236	Q9NPJ1
GSRSRNSTLTSLCVL	MADD	166	Q8WXG6
LSKNITRCGLSNSTL	LDB1	226	Q86U70
KAGITTTLNSRCSVL	MCM5	471	P33992
SAVRCLQKRGSATSS	FSD1	476	Q9BTV5
LCSTDGTFLSSLLKS	LIPT1	181	Q9Y234
LAKCSSRSLSQRLLS	KCNH6	136	Q9H252
DDISLSLGQSSSLCK	PCNX1	181	Q96RV3
RCRSSSGSSKALSTL	OR4K1	226	Q8NGD4
VTSSCSSQRLAKLTA	PGM2L1	121	Q6PCE3
RSSRKLSSALCAGSL	PDE3A	56	Q14432
LSQLLELGSSSRKTC	NFX1	601	Q12986
PRLSGSCSLNSLESK	LRRC71	106	Q8N4P6
CSLASLLVSVTSKGV	EXOSC7	221	Q15024
LSLSELKTFRLTSSC	NLRC5	1491	Q86WI3
QFTLRLGSKSVLSTC	RELN	771	P78509
SAILPALSRCSQLST	PRAMEF12	366	O95522
SGGLQSKRLSLDSSC	PAPOLG	516	Q9BWT3
KSLAGSCPSTRLLTL	ARHGAP33	531	O14559
GISTSATTNLKCSLL	APOB	1651	P04114
TLSLTSSFGTILRKC	BRCA2	656	P51587
LKRSSSETILSSLAG	CDR2	306	Q01850
SVLLLTSSLNCSFGS	GGT6	361	Q6P531
KGLRQTATLTCTGNS	IGLV10-54	31	A0A075B6I4
KRSVSGLCNSSSALP	RALGDS	776	Q12967
ARSAAGASSLKLQLT	HUS1B	91	Q8NHY5
RTCLGSLISTAKTQN	FOXN2	411	P32314
RSTSESTAALGCLVK	IGHG2	16	P01859
RSTSESTAALGCLVK	IGHG4	16	P01861
GLNLSSLAITRCNLS	LINGO4	251	Q6UY18
LGRSQTISFTSCLLQ	OR6F1	86	Q8NGZ6
NLTALSLSGCSKVTD	FBXL16	321	Q8N461
SAQKASLCLNGSSLS	PWWP3A	221	Q2TAK8
TTGLCLTSRSLLNRL	TREML2	241	Q5T2D2
LTNSGKRSPACSSLT	SPAG5	36	Q96R06
ALLGASIKLTCTLSS	IGLV4-3	31	A0A075B6K6
ASASLGSSVKLTCTL	IGLV4-60	31	A0A075B6I1
SLLACTSKNSSLLSI	KLRC2	141	P26717
SSLINSLKRSRACSV	GNL3L	266	Q9NVN8
RKTGSSTLAVALCST	SLC43A3	351	Q8NBI5
SLVSLCSSLRLFSSI	NINL	301	Q9Y2I6
LLLKATSAATLSCLG	OSBPL10	276	Q9BXB5
LRTLAGSSNKSLGCV	SKI	356	P12755
LTFLLCKAIRNTSTS	ADGRE3	376	Q9BY15
RSTVNCSDSLLSKLN	C12orf40	191	Q86WS4
LSCTLATGSTLFLGK	CLCNKA	151	P51800
LCSKSLSLLDLGSNA	NLRP9	796	Q7RTR0
STGSKRTFSSILCRL	TTLL11	451	Q8NHH1
SCILASTSLLTKGNR	TMEM269	151	A0A1B0GVZ9
ILRNKGCSSSTSVLL	THBS1	226	P07996
SLENRCLATLSSLKS	TEP1	106	Q99973
GCILLTLSAILSRST	MINDY4	566	Q4G0A6
TVLNISKSGSCSAIR	RSL1D1	201	O76021
RDSAKCIRTLTSSGQ	KIF21A	1416	Q7Z4S6
SALGTTIRLTCTLRN	VPREB1	31	P12018
LCSSTQSQALGSLRT	TTLL2	6	Q9BWV7
SNSLASCLSRLSGKS	USP38	426	Q8NB14
VALGSSKACLTDTRT	PLEKHA3	86	Q9HB20
KVSISCFGSLRNLSS	USP31	906	Q70CQ4
CRQTLGTLSLGTSSR	ZNF831	1371	Q5JPB2
SSLCLALTLLSSVQG	TRAPPC13	366	A5PLN9
LSRSSIGSIKCLQTT	TSBP1	111	Q5SRN2
VIKCSGQTSRLSASS	TTLL4	1171	Q14679
QCSSALGALDKLSST	nan	76	Q499Y3
SKSGLCRSVLTALLS	TM4SF19	86	Q96DZ7
SKSLSCLGGSRSLAL	KRT72	46	Q14CN4
RLKACSLAASEGLSS	KIAA1522	876	Q9P206
LCLSNTASSHGTRKL	MYO9A	2436	B2RTY4