Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucosamine-6-phosphate deaminase activity	GNPDA1 GNPDA2	1.01e-05	2	64	2	GO:0004342
GeneOntologyMolecularFunction	peptidase activity	ADAMTS10 BMP1 USP6 RELN CLCA4 CASP8 XPNPEP1 KLKB1 VCPIP1	2.26e-04	654	64	9	GO:0008233
GeneOntologyBiologicalProcess	glucosamine catabolic process	GNPDA1 GNPDA2	1.01e-05	2	66	2	GO:0006043
GeneOntologyBiologicalProcess	N-acetylglucosamine catabolic process	GNPDA1 GNPDA2	3.02e-05	3	66	2	GO:0006046
GeneOntologyCellularComponent	axonemal microtubule doublet inner sheath	EFHC2 CFAP52 EFCAB6	4.14e-04	46	66	3	GO:0160110
GeneOntologyCellularComponent	A axonemal microtubule	EFHC2 CFAP52 EFCAB6	4.41e-04	47	66	3	GO:0097649
GeneOntologyCellularComponent	axonemal doublet microtubule	EFHC2 CFAP52 EFCAB6	4.99e-04	49	66	3	GO:0097545
Domain	Glucosamine6P_isomerase_CS	GNPDA1 GNPDA2	1.19e-05	2	65	2	IPR018321
Domain	Glucosamine6P_isomerase	GNPDA1 GNPDA2	1.19e-05	2	65	2	IPR004547
Domain	GLC_GALNAC_ISOMERASE	GNPDA1 GNPDA2	1.19e-05	2	65	2	PS01161
Domain	Glc/Gal-6P_isomerase	GNPDA1 GNPDA2	7.12e-05	4	65	2	IPR006148
Domain	Glucosamine_iso	GNPDA1 GNPDA2	7.12e-05	4	65	2	PF01182
Domain	EGF_CA	CD93 BMP1 CRELD2 CUBN	2.29e-04	86	65	4	PF07645
Domain	EGF_Ca-bd_CS	CD93 BMP1 CRELD2 CUBN	3.63e-04	97	65	4	IPR018097
Domain	EGF_CA	CD93 BMP1 CRELD2 CUBN	3.92e-04	99	65	4	PS01187
Domain	ASX_HYDROXYL	CD93 BMP1 CRELD2 CUBN	4.08e-04	100	65	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	CD93 BMP1 CRELD2 CUBN	5.09e-04	106	65	4	IPR000152
Domain	CUB	BMP1 CUBN NRP2	6.61e-04	49	65	3	PF00431
Domain	CUB	BMP1 CUBN NRP2	7.02e-04	50	65	3	SM00042
Domain	-	BMP1 CUBN NRP2	7.87e-04	52	65	3	2.60.120.290
Domain	CUB	BMP1 CUBN NRP2	8.32e-04	53	65	3	PS01180
Domain	EGF_CA	CD93 BMP1 CRELD2 CUBN	8.63e-04	122	65	4	SM00179
Domain	EGF-like_Ca-bd_dom	CD93 BMP1 CRELD2 CUBN	9.17e-04	124	65	4	IPR001881
Domain	CUB_dom	BMP1 CUBN NRP2	1.03e-03	57	65	3	IPR000859
Domain	-	NWD2 DDX17 MDN1 ATAD1 NSF RAB30 AK7 DDX5 RAD17	1.06e-03	746	65	9	3.40.50.300
Domain	EGF_3	CD93 BMP1 RELN CRELD2 CUBN	1.35e-03	235	65	5	PS50026
Domain	EGF	CD93 BMP1 RELN CRELD2 CUBN	1.35e-03	235	65	5	SM00181
Domain	AT_hook	PRR12 DOT1L	1.39e-03	16	65	2	PF02178
Domain	AAA+_ATPase	MDN1 ATAD1 NSF RAD17	1.59e-03	144	65	4	IPR003593
Domain	AAA	MDN1 ATAD1 NSF RAD17	1.59e-03	144	65	4	SM00382
Domain	EGF-like_dom	CD93 BMP1 RELN CRELD2 CUBN	1.74e-03	249	65	5	IPR000742
Domain	Growth_fac_rcpt_	CD93 BMP1 CRELD2 CUBN	2.13e-03	156	65	4	IPR009030
Domain	EGF-like_CS	CD93 BMP1 RELN CRELD2 CUBN	2.14e-03	261	65	5	IPR013032
Domain	EGF_2	CD93 BMP1 RELN CRELD2 CUBN	2.29e-03	265	65	5	PS01186
Domain	P-loop_NTPase	NWD2 DDX17 MDN1 ATAD1 NSF RAB30 AK7 DDX5 RAD17	2.56e-03	848	65	9	IPR027417
Domain	AT_hook	PRR12 DOT1L	3.96e-03	27	65	2	SM00384
Domain	AT_hook_DNA-bd_motif	PRR12 DOT1L	3.96e-03	27	65	2	IPR017956
Domain	ATPase_AAA_CS	ATAD1 NSF	4.56e-03	29	65	2	IPR003960
Domain	HMGI/Y_DNA-bd_CS	PRR12 DOT1L	5.20e-03	31	65	2	IPR000637
Domain	DEAD_ATP_HELICASE	DDX17 DDX5	5.20e-03	31	65	2	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX17 DDX5	5.87e-03	33	65	2	IPR000629
Domain	AAA	ATAD1 NSF	6.23e-03	34	65	2	PS00674
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PRR12 CDSN DDX17 MDN1 NSF RGS3 DDX5	9.65e-07	272	67	7	31010829
Pubmed	The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways.	DDX17 DDX5	3.66e-06	2	67	2	24275493
Pubmed	Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes.	DDX17 DDX5	3.66e-06	2	67	2	38782119
Pubmed	Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.	GNPDA1 GNPDA2	3.66e-06	2	67	2	12965206
Pubmed	Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.	GNPDA1 GNPDA2	3.66e-06	2	67	2	12616532
Pubmed	Involvement of RNA helicases p68 and p72 in colon cancer.	DDX17 DDX5	3.66e-06	2	67	2	17699760
Pubmed	Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis.	DDX17 DDX5	3.66e-06	2	67	2	18005418
Pubmed	The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells.	DDX17 DDX5	3.66e-06	2	67	2	12595555
Pubmed	Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas.	DDX17 DDX5	3.66e-06	2	67	2	32008867
Pubmed	The roles of DEAD box helicases in the life cycle of HIV-1.	DDX17 DDX5	3.66e-06	2	67	2	26312911
Pubmed	SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1.	PIAS1 DDX5	1.10e-05	3	67	2	17369852
Pubmed	Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.	DDX17 DDX5	1.10e-05	3	67	2	23022728
Pubmed	RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.	DDX17 DDX5	1.10e-05	3	67	2	24910439
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	SCHIP1 IQCJ-SCHIP1	1.10e-05	3	67	2	17045569
Pubmed	The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.	DDX17 DDX5	1.10e-05	3	67	2	19718048
Pubmed	Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.	DDX17 DDX5	1.10e-05	3	67	2	22266867
Pubmed	The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.	DDX17 DDX5	1.10e-05	3	67	2	15298701
Pubmed	DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.	DOT1L LGR5	1.10e-05	3	67	2	23428873
Pubmed	AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF.	ATAD1 NSF	1.10e-05	3	67	2	33147468
Pubmed	The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor.	DDX17 DDX5	2.19e-05	4	67	2	15660129
Pubmed	Caspase-8 sumoylation is associated with nuclear localization.	CASP8 PIAS1	2.19e-05	4	67	2	15782135
Pubmed	Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions.	DDX17 DDX5	2.19e-05	4	67	2	32463358
Pubmed	Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.	SCHIP1 IQCJ-SCHIP1	2.19e-05	4	67	2	27979964
Pubmed	Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells.	DDX17 DDX5	2.19e-05	4	67	2	25604459
Pubmed	Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.	DDX17 PRPF38A DDX5	2.67e-05	30	67	3	24140279
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	DDX17 DLC1 MDN1 EFCAB6 SYTL4 RAB30 GNPDA2 SNRK CUBN RGS3 DDX5	3.42e-05	1293	67	11	15342556
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	SCHIP1 IQCJ-SCHIP1	3.64e-05	5	67	2	25950943
Pubmed	Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression.	IGF2R LGR5	3.64e-05	5	67	2	31388182
Pubmed	Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.	DDX17 DDX5	3.64e-05	5	67	2	18279852
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	SCHIP1 IQCJ-SCHIP1	3.64e-05	5	67	2	18550753
Pubmed	Colonic CD90+ Crypt Fibroblasts Secrete Semaphorins to Support Epithelial Growth.	LGR5 NRP2	3.64e-05	5	67	2	30917322
Pubmed	Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication - a targeted small interfering RNA library screen using pseudotyped and WT HIV-1.	DDX17 DDX5	3.64e-05	5	67	2	25701821
Pubmed	Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.	GNPDA1 GNPDA2	3.64e-05	5	67	2	26887390
Pubmed	Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.	SCHIP1 IQCJ-SCHIP1 CUBN	3.92e-05	34	67	3	19197348
Pubmed	De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.	EFHC2 CFAP52 EFCAB6	4.28e-05	35	67	3	37865089
Pubmed	In-cell structural insight into the stability of sperm microtubule doublet.	EFHC2 CFAP52 EFCAB6	4.66e-05	36	67	3	37989994
Pubmed	Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function.	DDX17 DDX5	5.46e-05	6	67	2	23608157
Pubmed	The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.	DDX17 DDX5	5.46e-05	6	67	2	17011493
Pubmed	Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.	DDX17 DDX5	7.63e-05	7	67	2	19995069
Pubmed	The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.	SCHIP1 NRP2	1.02e-04	8	67	2	25953347
Pubmed	Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.	DDX17 DDX5	1.02e-04	8	67	2	20663877
Pubmed	Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function.	DOT1L NRP2	1.02e-04	8	67	2	31908356
Pubmed	Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.	EFHC2 CFAP52 EFCAB6	1.18e-04	49	67	3	37295417
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP6 IGF2R ATAD1 SYTL4 NSF ALDH3A2 PAAF1 RAD17 VCPIP1	1.29e-04	1005	67	9	19615732
Pubmed	Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.	DDX17 DDX5	1.30e-04	9	67	2	24581491
Pubmed	The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis.	DTX1 CASP8	1.30e-04	9	67	2	35044632
Pubmed	FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.	RELN CASP8	1.30e-04	9	67	2	20554749
Pubmed	DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.	RELN DOT1L NRP2	1.41e-04	52	67	3	37566909
Pubmed	Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.	DDX17 DDX5	1.63e-04	10	67	2	12738788
Pubmed	The shieldin complex mediates 53BP1-dependent DNA repair.	PRR12 IGF2R ALDH3A2	1.76e-04	56	67	3	30022168
Pubmed	Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.	DDX17 DDX5	1.99e-04	11	67	2	21900255
Pubmed	Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.	DDX17 DDX5	2.38e-04	12	67	2	16595651
Pubmed	A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture.	DDX17 DDX5	2.38e-04	12	67	2	26041499
Pubmed	A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.	DDX17 DDX5	2.81e-04	13	67	2	30792309
Pubmed	Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.	DDX17 DDX5	2.81e-04	13	67	2	17765891
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	DDX17 IGF2R PRPF38A ALDH3A2 DDX5	2.88e-04	300	67	5	28561026
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	ADAMTS10 CRELD2 CASP8 HMGCL PRPF38A XPNPEP1 PAAF1 CRIP2 DDX5	2.96e-04	1124	67	9	21900206
Pubmed	Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.	SLC35G1 NWD2 CUBN NRP2	3.04e-04	166	67	4	19906978
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	DDX17 IGF2R MDN1 HMGCL ALDH3A2 DDX5 PTK7	3.51e-04	686	67	7	28380382
Pubmed	Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.	IGF2R KLKB1 PTK7	3.56e-04	71	67	3	12754519
Pubmed	Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System.	RELN NRP2	3.78e-04	15	67	2	27667971
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DDX17 IGF2R NSF XPNPEP1 ALDH3A2 DDX5 VCPIP1	4.24e-04	708	67	7	39231216
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SPATA7 IGF2R ATAD1 NSF SPTLC1 HMGCL ALDH3A2 PTK7 NRP2 VCPIP1	4.40e-04	1451	67	10	30550785
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	BMP1 SIAE IGF2R SPTLC1 CRELD2 ALDH3A2 CRIP2 PTK7 NRP2	4.79e-04	1201	67	9	35696571
Pubmed	Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.	CD93 KLKB1	4.88e-04	17	67	2	19372141
Pubmed	Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool.	RELN NRP2	4.88e-04	17	67	2	18521945
Pubmed	Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream.	RELN NRP2	4.88e-04	17	67	2	23292680
Pubmed	Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.	SLC12A3 CUBN	4.88e-04	17	67	2	29449453
Pubmed	Arx homeobox gene is essential for development of mouse olfactory system.	RELN NRP2	4.88e-04	17	67	2	15677725
Pubmed	Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.	SLC12A3 CUBN	4.88e-04	17	67	2	21082674
Pubmed	A physical interaction network of dengue virus and human proteins.	PIAS1 DDX5	5.48e-04	18	67	2	21911577
Pubmed	TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.	DDX17 SYTL4	5.48e-04	18	67	2	32924931
Pubmed	Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development.	RELN NRP2	5.48e-04	18	67	2	21991391
Pubmed	Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein.	HMGCL SIRT5	8.24e-04	22	67	2	26767982
Pubmed	Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.	DDX17 DDX5	8.24e-04	22	67	2	26420826
Pubmed	Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.	RELN DOT1L	8.24e-04	22	67	2	32471461
Pubmed	DNA cloning using in vitro site-specific recombination.	SPATA7 CD93 SLC12A3 RCBTB1 SIRT5 RAD17 VCPIP1	8.34e-04	794	67	7	11076863
Pubmed	Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.	RELN NRP2	9.01e-04	23	67	2	25875176
Pubmed	DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.	RELN DOT1L	9.01e-04	23	67	2	30329130
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PPP1R13B DOT1L ALDH3A2 PIAS1 DDX5 VCPIP1	9.49e-04	588	67	6	38580884
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	SIAE KLKB1	9.82e-04	24	67	2	24625756
Pubmed	Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.	BMP1 IGF2R	9.82e-04	24	67	2	12421715
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	DDX17 MDN1 PIAS1	1.14e-03	106	67	3	19394292
Pubmed	The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways.	RELN NRP2	1.15e-03	26	67	2	23988635
Pubmed	Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.	DLC1 LGR5	1.15e-03	26	67	2	28193997
Pubmed	Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.	DDX17 DDX5	1.24e-03	27	67	2	36266428
Pubmed	Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.	BMP1 NRP2	1.24e-03	27	67	2	24586749
Pubmed	The DNA sequence and analysis of human chromosome 14.	SPATA7 PPP1R13B AK7	1.31e-03	111	67	3	12508121
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	IGF2R SYTL4 SPTLC1 PPP1R13B PTK7	1.32e-03	421	67	5	36976175
Pubmed	Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.	SLC12A3 CUBN	1.34e-03	28	67	2	28847650
Pubmed	Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells.	RELN NRP2	1.34e-03	28	67	2	27178193
Pubmed	Impaired Interneuron Development after Foxg1 Disruption.	RELN NRP2	1.44e-03	29	67	2	26620267
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	DDX17 MDN1 DDX5	1.48e-03	116	67	3	21549307
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	CUBN PTK7 NRP2	1.52e-03	117	67	3	17145500
Pubmed	Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.	DDX17 DDX5	1.54e-03	30	67	2	22963397
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CDSN DDX17 IGF2R MDN1 NSF SPTLC1 HMGCL ALDH3A2 DDX5	1.60e-03	1425	67	9	30948266
Pubmed	High-throughput mapping of a dynamic signaling network in mammalian cells.	RAPSN RAB30 SKI RGS3	1.62e-03	260	67	4	15761153
Pubmed	HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres.	DDX17 DDX5	1.64e-03	31	67	2	20080577
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	PPP1R13B ALDH3A2 DDX5 VCPIP1	1.69e-03	263	67	4	34702444
Pubmed	Vti1b promotes TRPV1 sensitization during inflammatory pain.	DDX17 ATAD1 CRIP2	1.92e-03	127	67	3	30335684
GeneFamily	AAA ATPases	MDN1 ATAD1 NSF	2.70e-04	53	43	3	413
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	EVA1C RELN SCHIP1 MDN1 EFCAB6 CRIP2	1.59e-07	161	67	6	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C SCHIP1 SNRK CRIP2 NRP2	3.28e-07	182	67	6	d996ceb77c83591df4cef144ca72862f31d9777f
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C SCHIP1 SYTL4 SNRK CRIP2	4.09e-07	189	67	6	1d660bceee449aebf12fc9af4c74af246837b27a
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C IGF2R DTX1 NEXMIF RGS3 PTK7	4.63e-07	193	67	6	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD93 EVA1C SCHIP1 DLC1 PPP1R13B SNRK	4.92e-07	195	67	6	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C RELN DLC1 CRIP2 NRP2	5.37e-07	198	67	6	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 CASP8 SIRT5 CRIP2	7.66e-06	180	67	5	2405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 CASP8 SIRT5 CRIP2	7.66e-06	180	67	5	9c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 CASP8 SIRT5 CRIP2	7.66e-06	180	67	5	499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	7.87e-06	181	67	5	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	8.08e-06	182	67	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	8.75e-06	185	67	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	8.75e-06	185	67	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	9.45e-06	188	67	5	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 PPP1R13B SNRK AK7 CRIP2	9.45e-06	188	67	5	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	9.45e-06	188	67	5	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 SCHIP1 PPP1R13B RGS3 CRIP2	9.70e-06	189	67	5	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	facs-Kidney-nan-24m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	9.70e-06	189	67	5	9d02a824bba59ea0660439f0510d843568e9d8c3
ToppCell	facs-Kidney-nan-24m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	9.70e-06	189	67	5	5f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCell	3'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C SCHIP1 SNRK CRIP2	9.70e-06	189	67	5	0c612ff5f882f2d8ec744a347780bbbe7cc471bd
ToppCell	facs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	9.70e-06	189	67	5	18f82764b32496e54d1a604a531b261651c5e110
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C SCHIP1 SNRK CRIP2	9.70e-06	189	67	5	bc8949bd4f425ed36e2c05e653c94cb1593c5bee
ToppCell	droplet-Heart-HEART-1m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 CFAP52 SNRK CRIP2 NRP2	9.70e-06	189	67	5	4225bbff4037eecc93a12abad3a38dd04b1e22be
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	9.70e-06	189	67	5	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	9.70e-06	189	67	5	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	1.02e-05	191	67	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	1.02e-05	191	67	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	1.02e-05	191	67	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	1.05e-05	192	67	5	1a2dd398141069ef6ad2f6bb4bae0bac1c6b98e8
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	1.05e-05	192	67	5	5dd206adb8b84c374ee931f7df2a8b8cf040efab
ToppCell	droplet-Kidney-nan-3m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	1.05e-05	192	67	5	85be54c2cba8eab4c6ef2a85a526f7a9db4cfe73
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2 NRP2	1.05e-05	192	67	5	31a9142d97b690992aabee1a181650deb1a44253
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK DDX5 NRP2	1.07e-05	193	67	5	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EFHC2 CFAP52 EFCAB6 DLEC1 AK7	1.10e-05	194	67	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	DDX17 DLC1 SNRK IQCJ-SCHIP1 CRIP2	1.27e-05	200	67	5	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DLC1 SNRK IQCJ-SCHIP1 RGS3 CRIP2	1.27e-05	200	67	5	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C RELN CRIP2 NRP2	1.27e-05	200	67	5	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS10 DLC1 KLKB1 RGS3	7.33e-05	148	67	4	c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN CLCA4 DTX1 NRP2	1.02e-04	161	67	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN CLCA4 DTX1 NRP2	1.02e-04	161	67	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA7 MDN1 DTX1 RAB30	1.02e-04	161	67	4	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN CLCA4 DTX1 NRP2	1.02e-04	161	67	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN CLCA4 DTX1 NRP2	1.04e-04	162	67	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCHIP1 SLC12A3 RAB30 CRELD2	1.12e-04	165	67	4	6e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 RAPSN DTX1 LACTBL1	1.12e-04	165	67	4	8c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCell	droplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CRELD2 DLEC1 CUBN	1.12e-04	165	67	4	21a82a975f550080b6674750b06212205cd16742
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7\|TCGA-Kidney / Sample_Type by Project: Shred V9	RELN DLEC1 IQCJ-SCHIP1 AK7	1.14e-04	166	67	4	b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK NRP2	1.31e-04	172	67	4	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	RELN DTX1 NEXMIF NRP2	1.31e-04	172	67	4	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN KLKB1 AK7 NRP2	1.34e-04	173	67	4	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD93 EVA1C RGS3 CRIP2	1.34e-04	173	67	4	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN DTX1 CRIP2 NRP2	1.34e-04	173	67	4	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPSN GLB1L3 CUBN CRIP2	1.37e-04	174	67	4	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 SLC35G1 ATAD1 CRIP2	1.37e-04	174	67	4	feed99acd868db61f045e666dbfdcaed91ca1488
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EVA1C RELN DLC1 LGR5	1.43e-04	176	67	4	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CD93 PRR12 DLC1 RCBTB1	1.46e-04	177	67	4	6da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.49e-04	178	67	4	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C SNRK RGS3 CRIP2	1.49e-04	178	67	4	e2363810d77b6b245394a666eb51bacd345c43f7
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CRELD2 CUBN AK7	1.49e-04	178	67	4	b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 PPP1R13B RGS3 CRIP2	1.59e-04	181	67	4	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 EVA1C RGS3 CRIP2	1.63e-04	182	67	4	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN DLC1 CRIP2 NRP2	1.63e-04	182	67	4	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	droplet-Fat-Scat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 SCHIP1 SNRK CRIP2	1.63e-04	182	67	4	fea094fe0e7796c084e60b5310c1559658633f7a
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN DTX1 KLKB1 NRP2	1.66e-04	183	67	4	a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN DTX1 KLKB1 NRP2	1.66e-04	183	67	4	13ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C CFAP52 KLKB1 AK7	1.70e-04	184	67	4	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN DLC1 CRIP2 NRP2	1.70e-04	184	67	4	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C CFAP52 KLKB1 AK7	1.70e-04	184	67	4	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C CFAP52 KLKB1 AK7	1.70e-04	184	67	4	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.70e-04	184	67	4	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DTX1 NEXMIF LGR5	1.73e-04	185	67	4	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD93 EVA1C SCHIP1 PPP1R13B	1.73e-04	185	67	4	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.73e-04	185	67	4	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.73e-04	185	67	4	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DTX1 NEXMIF LGR5	1.73e-04	185	67	4	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	droplet-Kidney-nan-3m-Endothelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2	1.77e-04	186	67	4	d72cdbb6d79ab33a5823c42e93c2ba566244f64c
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)\|343B / Donor, Lineage, Cell class and subclass (all cells)	RELN DTX1 CRIP2 NRP2	1.77e-04	186	67	4	7a8da2ad140bea3207bd868212cc5e201d586772
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	RELN DTX1 CRIP2 NRP2	1.77e-04	186	67	4	dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	EFHC2 CFAP52 DLEC1 AK7	1.81e-04	187	67	4	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 PPP1R13B SNRK CRIP2	1.81e-04	187	67	4	50d5730e2cd4951d3ad0641fc81ae9f6ddabafe7
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 CRIP2 NRP2	1.81e-04	187	67	4	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	367C-Endothelial_cells-Endothelial-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	CD93 IQCJ-SCHIP1 CRIP2 NRP2	1.81e-04	187	67	4	1342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell	367C-Endothelial_cells-Endothelial-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CD93 IQCJ-SCHIP1 CRIP2 NRP2	1.81e-04	187	67	4	7aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.81e-04	187	67	4	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 CRIP2 NRP2	1.81e-04	187	67	4	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	droplet-Fat-SCAT-30m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2	1.84e-04	188	67	4	e901a9bdf00b8e91806f445af66647373bf62661
ToppCell	droplet-Fat-SCAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2	1.84e-04	188	67	4	5cf060bb8adaefa9964187195d67993c1248ef47
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFHC2 CFAP52 DLEC1 AK7	1.84e-04	188	67	4	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	RELN RGS3 CRIP2 NRP2	1.84e-04	188	67	4	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	droplet-Fat-SCAT-30m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 DLC1 SNRK CRIP2	1.84e-04	188	67	4	449f9602df3c83b2110eb479a00d428d1b55b423
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EVA1C RELN DTX1 NRP2	1.84e-04	188	67	4	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EFHC2 CFAP52 DLEC1 AK7	1.88e-04	189	67	4	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	EFHC2 DLC1 SYTL4 PTK7	1.88e-04	189	67	4	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFHC2 CFAP52 EFCAB6 DLEC1	1.88e-04	189	67	4	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 PPP1R13B RGS3 CRIP2	1.88e-04	189	67	4	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	BMP1 RAPSN RGS3 NRP2	1.88e-04	189	67	4	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD93 EVA1C SCHIP1 CRIP2	1.88e-04	189	67	4	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 CDSN SNRK CRIP2	1.88e-04	189	67	4	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	EFHC2 CFAP52 EFCAB6 AK7	1.88e-04	189	67	4	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD93 RELN DTX1 NRP2	1.88e-04	189	67	4	28b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
Disease	level of Sterol ester (27:1/20:5) in blood serum	NWD2 RAPSN DAGLA	1.66e-06	11	65	3	OBA_2045197
Disease	gamma-linolenic acid measurement	RAPSN DOT1L DAGLA	2.00e-05	24	65	3	EFO_0007762
Disease	Abnormality of refraction	DLC1 RCBTB1 GNPDA2 DLEC1 DAGLA RGS3 DDX5 LACTBL1	1.13e-04	673	65	8	HP_0000539
Disease	intraocular pressure measurement	EFHC2 EVA1C RELN RAPSN DLC1 NSF DLEC1	1.28e-04	509	65	7	EFO_0004695
Disease	acne	RAPSN DLC1 CRELD2 DLEC1	1.70e-04	125	65	4	EFO_0003894
Disease	HEPATOCELLULAR CARCINOMA	IGF2R CASP8	1.70e-04	9	65	2	114550
Disease	age at onset, coronary stenosis	DLC1 DLEC1	1.70e-04	9	65	2	EFO_0004847, MONDO_0006715
Disease	Hepatocellular carcinoma	IGF2R CASP8	1.70e-04	9	65	2	cv:C2239176
Disease	level of Phosphatidylcholine (O-18:0_20:4) in blood serum	RAPSN DAGLA	1.70e-04	9	65	2	OBA_2045127
Disease	level of Phosphatidylcholine (16:0_22:4) in blood serum	RAPSN DAGLA	1.70e-04	9	65	2	OBA_2045078
Disease	abdominal obesity-metabolic syndrome (implicated_via_orthology)	DDX17 DDX5	2.13e-04	10	65	2	DOID:0060611 (implicated_via_orthology)
Disease	neutropenia, response to gemcitabine	DLC1 DLEC1	2.59e-04	11	65	2	GO_0036272, MONDO_0001475
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	RAPSN DAGLA	3.11e-04	12	65	2	OBA_2045157
Disease	level of Phosphatidylcholine (O-16:0_20:4) in blood serum	RAPSN DAGLA	3.67e-04	13	65	2	OBA_2045116
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	RAPSN DAGLA	4.27e-04	14	65	2	EFO_0022085
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	RAPSN DAGLA	4.27e-04	14	65	2	OBA_2045100
Disease	level of Phosphatidylethanolamine (18:2_0:0) in blood serum	RAPSN DAGLA	4.27e-04	14	65	2	OBA_2045143
Disease	lysophosphatidylcholine 22:5 measurement	RAPSN DAGLA	4.27e-04	14	65	2	EFO_0021462
Disease	venous thromboembolism	CD93 RELN DLC1 DLEC1 ZC3H3 KLKB1	5.28e-04	460	65	6	EFO_0004286
Disease	phosphatidylcholine 38:3 measurement	RAPSN IGF2R	5.62e-04	16	65	2	EFO_0010385
Disease	interleukin 18 measurement	PRR12 RELN RAD17	6.39e-04	76	65	3	EFO_0004581
Disease	level of Phosphatidylcholine (20:4_0:0) in blood serum	RAPSN DAGLA	7.15e-04	18	65	2	OBA_2045110
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	RAPSN DAGLA	7.15e-04	18	65	2	OBA_2045065
Disease	level of Phosphatidylcholine (16:0_22:5) in blood serum	RAPSN DAGLA	7.15e-04	18	65	2	OBA_2045079
Disease	obsessive-compulsive disorder, autism spectrum disorder	DLC1 DLEC1	7.98e-04	19	65	2	EFO_0003756, EFO_0004242
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	RAPSN DAGLA	9.77e-04	21	65	2	OBA_2045104
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	RAPSN DAGLA	9.77e-04	21	65	2	OBA_2045076
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	RAPSN DAGLA	9.77e-04	21	65	2	OBA_2045083
Disease	childhood aggressive behaviour measurement	DLC1 SNRK DLEC1	1.01e-03	89	65	3	EFO_0007663
Disease	erosive tooth wear measurement	GNPDA1 DLC1 DLEC1	1.05e-03	90	65	3	EFO_0009331
Disease	sensory peripheral neuropathy, remission	DLC1 DLEC1	1.17e-03	23	65	2	EFO_0009785, MONDO_0002321
Disease	platelet component distribution width	RAPSN DLC1 SYTL4 BTBD7 DLEC1 CUBN SKI	1.34e-03	755	65	7	EFO_0007984
Disease	alpha-linolenic acid measurement	RAPSN DAGLA	1.39e-03	25	65	2	EFO_0007759
Disease	lysophosphatidylethanolamine 18:2 measurement	RAPSN DAGLA	1.50e-03	26	65	2	EFO_0010369
Disease	level of Phosphatidylcholine (17:0_20:4) in blood serum	RAPSN DAGLA	1.50e-03	26	65	2	OBA_2045087
Disease	docosapentaenoic acid measurement	RAPSN DAGLA	1.62e-03	27	65	2	EFO_0006809
Disease	caudate volume change measurement, age at assessment	DLC1 DLEC1	1.62e-03	27	65	2	EFO_0008007, EFO_0021491
Disease	transforming growth factor beta measurement	DLC1 DLEC1	1.62e-03	27	65	2	EFO_0004818
Disease	bipolar disorder	SIAE RAPSN DLC1 PPP1R13B DLEC1 XPNPEP1	1.69e-03	577	65	6	MONDO_0004985
Disease	Oral ulcer	CDSN SCHIP1 IQCJ-SCHIP1	1.72e-03	107	65	3	HP_0000155
Disease	stimulant use measurement	DLC1 DLEC1	1.74e-03	28	65	2	EFO_0600076
Disease	phosphatidylcholine 38:4 measurement	RAPSN DAGLA	1.74e-03	28	65	2	EFO_0010386
Disease	level of Phosphatidylethanolamine (18:0_18:2) in blood serum	RAPSN DAGLA	1.74e-03	28	65	2	OBA_2045139
Disease	peptide measurement	DLC1 DLEC1 KLKB1	1.81e-03	109	65	3	EFO_0010520
Disease	diverticular disease	DLC1 DLEC1 IQCJ-SCHIP1 PIAS1	1.84e-03	236	65	4	EFO_0009959
Disease	gas trapping measurement	DLC1 DLEC1	1.87e-03	29	65	2	EFO_0007628
Disease	lysophosphatidylethanolamine 20:4 measurement	RAPSN DAGLA	1.87e-03	29	65	2	EFO_0010370
Disease	Neural Tube Defects	SKI PTK7	2.00e-03	30	65	2	C0027794
Disease	endometrial carcinoma	DLC1 MDN1 DLEC1	2.01e-03	113	65	3	EFO_1001512
Disease	level of Sterol ester (27:1/20:4) in blood serum	RAPSN DAGLA	2.13e-03	31	65	2	OBA_2045198
Disease	level of Phosphatidylcholine (18:0_20:4) in blood serum	RAPSN DAGLA	2.13e-03	31	65	2	OBA_2045094

Protein segments in the cluster

Peptide	Gene	Start	Entry
KGKCLDPSLPLKGFS	CD93	101	Q9NPY3
LTPVTLELGGKSPCY	ALDH3A2	201	P51648
LCGPTDKTPLLSGKA	DOT1L	1396	Q8TEK3
KPCPPITSVDKSYGG	CDSN	281	Q15517
FCGSKKPEPVLATGS	BMP1	821	P13497
KAVYGKPVLPSGSTS	PPP1R13B	606	Q96KQ4
CIYKNKPCGTLGLAP	ADAMTS10	351	Q9H324
PLIIYGGPCTGKTLL	NWD2	411	Q9ULI1
LCGKKIKSLSYGSGP	RCBTB1	71	Q8NDN9
KTISYCKTCLGLPGT	RAPSN	101	Q13702
PLPGEGKSISYLTCC	RAB30	186	Q15771
TGPPGCGKTTTLKIL	RAD17	136	O75943
GLISKQPGTCDPYVK	RGS3	161	P49796
LLTYKPKCLGEGGKA	MDN1	2151	Q9NU22
TLGLPTGSTPLGCYK	GNPDA1	36	P46926
CGTLKAGPSPKDTFL	GLB1L3	576	Q8NCI6
LKSTCIYGGAPKGPQ	DDX5	196	P17844
GLLVFCKSPGYKPIK	CFAP52	271	Q8N1V2
KCSIYPKGDGSDVPS	EFHC2	56	Q5JST6
HVGPLIGKYCGTKTP	NRP2	221	O60462
ILLYGPPGCGKTLLA	NSF	256	P46459
CKAIYGEKTGTQPPG	DTX1	471	Q86Y01
KPSLYGSLTCQGIGL	PAAF1	31	Q9BRP4
DPGYSGPTCKISTKN	RELN	2151	P78509
LGRYCGKSIPPSLTS	CUBN	1001	O60494
SNSPLLGKYCGTLLP	CUBN	3461	O60494
LGKYCGTLLPNPVFS	CUBN	3466	O60494
GPDLCPGSSKYLLVS	EVA1C	141	P58658
AKTLLAPLLACPGAY	LACTBL1	281	A8MY62
LYKKLLACIGIDGPP	EFCAB6	561	Q5THR3
SGLKSAYLPGQTSPK	BTBD7	986	Q9P203
TGLKCPSLAGKPKVF	CASP8	341	Q14790
TLGLPTGSTPLGCYK	GNPDA2	36	Q8TDQ7
TLKCFAYSPPGGLLS	DAGLA	491	Q9Y4D2
CLLKYSPGGTPTAIK	KLKB1	166	P03952
SRLKSTCIYGGAPKG	DDX17	271	Q92841
KPCYGILFGPKGVNT	CRIP2	176	P52943
VKTLKVCCSPGTYGP	CRELD2	121	Q6UXH1
SAPKGISLPGCSKLT	DLEC1	221	Q9Y238
LGGSKYGASPLCLPL	LGR5	701	O75473
VYKDGSPCPSKSGLS	IGF2R	1591	P11717
VSLKYIPASKTPVGG	SYTL4	501	Q96C24
VLLYGPPGCAKTTLV	SPATA5L1	501	Q9BVQ7
PGIYTSCSKSGKPSL	SCHIP1	276	P0DPB3
LKGTLKSAPLGAPSC	NEXMIF	671	Q5QGS0
ALGCPYEGKISPAKV	HMGCL	171	P35914
SLKACGVPKQGSIPY	SIAE	231	Q9HAT2
LAGGPLVGILCSYSK	OR7A17	206	O14581
GPGIYTSCSKSGKPS	IQCJ-SCHIP1	351	B3KU38
VKVNTKPCSLPGYLP	PIAS1	221	O75925
KGGLTSPIFCSTKPK	PRR12	1056	Q9ULL5
SRYLIEPCGPGKSKL	DLC1	1466	Q96QB1
QPGKKLTTSCGSLAY	SNRK	166	Q9NRH2
GKCKGLLVPELYSSP	SKI	226	P12755
ALASLKKYGVGTCGP	SPTLC1	121	O15269
ALCKEYGETKGPGPT	BROX	286	Q5VW32
LYGPPGCGKTLIAKA	ATAD1	131	Q8NBU5
PTYPLGGTSICSGIK	CLCA4	376	Q14CN2
GLKPLSGETPLSAYK	ZC3H3	426	Q8IXZ2
RPCKPLLTLGLDYTG	XPNPEP1	161	Q9NQW7
CYGKGLKGPLLPETY	THAP9	526	Q9H5L6
TLPIGRKGKCPSSLY	SLC12A3	976	P55017
YGPPCLFKGHLSTKS	SPATA7	16	Q9P0W8
YGGNIKPTPFLCLTL	PRPF38A	61	Q8NAV1
TFLPGLIPAEKCTGK	VCPIP1	321	Q96JH7
AKKKAPCPGLGLFYT	SLC35G1	61	Q2M3R5
YKSPICPALSGKGAP	SIRT5	176	Q9NXA8
GKPGYLDCLTQATPK	PTK7	426	Q13308
PVPASRGGKTLCKGY	USP6	371	P35125
CILGPPAVGKSSIAK	AK7	371	Q96M32