Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcytoplasmic region

SPATA7 HAP1 IQSEC2 RIMBP2 DTNBP1 DNAH7 DRC3

1.13e-04360647GO:0099568
DomainSpectrin

TRIO KALRN MACF1 UTRN

8.70e-0723614PF00435
DomainSpectrin_repeat

TRIO KALRN MACF1 UTRN

2.30e-0629614IPR002017
DomainSpectrin/alpha-actinin

TRIO KALRN MACF1 UTRN

3.46e-0632614IPR018159
DomainSPEC

TRIO KALRN MACF1 UTRN

3.46e-0632614SM00150
DomainCaskin_C

CASKIN2 CASKIN1

1.05e-052612IPR032117
DomainCaskin-tail

CASKIN2 CASKIN1

1.05e-052612PF16632
DomainSH3

TRIO KALRN CASKIN2 CASKIN1 MACF1 RIMBP2

7.29e-05216616PS50002
DomainSH3_domain

TRIO KALRN CASKIN2 CASKIN1 MACF1 RIMBP2

8.07e-05220616IPR001452
DomainPH

TRIO KALRN IQSEC2 FGD5 PLEKHM3 APBB1IP

2.88e-04278616SM00233
DomainPH_DOMAIN

TRIO KALRN IQSEC2 FGD5 PLEKHM3 APBB1IP

2.94e-04279616PS50003
DomainPH_domain

TRIO KALRN IQSEC2 FGD5 PLEKHM3 APBB1IP

2.99e-04280616IPR001849
DomainCopine

CPNE2 CPNE4

3.72e-049612PF07002
DomainCopine

CPNE2 CPNE4

3.72e-049612IPR010734
DomainSH3

TRIO KALRN CASKIN2 CASKIN1 RIMBP2

6.94e-04216615SM00326
DomainARM-type_fold

IPO5 MYBBP1A MROH2B VPS35 KPNA6 VIRMA

8.20e-04339616IPR016024
DomainPH

TRIO KALRN FGD5 PLEKHM3 APBB1IP

9.03e-04229615PF00169
DomainRhoGEF

TRIO KALRN FGD5

1.43e-0368613SM00325
DomainRhoGEF

TRIO KALRN FGD5

1.55e-0370613PF00621
DomainDH_2

TRIO KALRN FGD5

1.55e-0370613PS50010
DomainDH-domain

TRIO KALRN FGD5

1.62e-0371613IPR000219
Domain-

TRIO KALRN FGD5

1.62e-03716131.20.900.10
Domain-

TRIO KALRN IQSEC2 FGD5 PLEKHM3 APBB1IP

1.70e-033916162.30.29.30
DomainCRAL_TRIO

TRIO KALRN

2.12e-0321612PF00650
DomainActinin_actin-bd_CS

MACF1 UTRN

2.54e-0323612IPR001589
Domain-

TRIO KALRN

2.54e-03236123.40.525.10
DomainACTININ_2

MACF1 UTRN

2.54e-0323612PS00020
DomainACTININ_1

MACF1 UTRN

2.54e-0323612PS00019
DomainPH_dom-like

TRIO KALRN IQSEC2 FGD5 PLEKHM3 APBB1IP

2.62e-03426616IPR011993
DomainSH3_2

CASKIN2 CASKIN1 RIMBP2

2.80e-0386613IPR011511
DomainSH3_2

CASKIN2 CASKIN1 RIMBP2

2.80e-0386613PF07653
DomainSEC14

TRIO KALRN

3.00e-0325612SM00516
DomainCRAL_TRIO

TRIO KALRN

3.49e-0327612PS50191
DomainCRAL-TRIO_dom

TRIO KALRN

3.76e-0328612IPR001251
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

FOXO3 FOXO6 ATXN3

5.45e-0522483MM15656
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES

FOXO3 FOXO6 ATXN3

1.41e-0430483M27941
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FOXO3 AMER1 INTS12 TRIO CASKIN2 IQSEC2 MACF1 PLEKHM3 MTREX DDX41 UTRN VIRMA DNAH7

4.92e-09861641336931259
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

IPO5 TRIO KALRN CEP57L1 MACF1 DTNBP1 UTRN

1.28e-0815164717043677
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYBBP1A VPS35 MACF1 HERC1 MTREX VIRMA EFTUD2

2.56e-0723464736243803
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

IPO5 PTGES2 ABCA2 TRIO KALRN IQSEC2 CEP57L1 POLR1C MACF1 YY1AP1 KPNA6 UTRN SLC4A3

5.12e-071285641335914814
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

IPO5 USP45 VPS35 POLR1C ATXN3 RIMBP2 DTNBP1 DDX41 UTRN AKAP7 EFTUD2

2.04e-061005641119615732
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

IPO5 MYBBP1A VPS35 UFL1 KPNA6 MTREX DDX41 SON EFTUD2

2.49e-0663864933239621
Pubmed

Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain.

HAP1 ATXN3

3.33e-06264221386698
Pubmed

Central FoxO3a and FoxO6 expression is down-regulated in obesity induced diabetes but not in aging.

FOXO3 FOXO6

3.33e-06264222187289
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

3.33e-06264226858404
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

IPO5 MYBBP1A ATAD5 PHF14 KPNA6 DDX41 UTRN

8.09e-0639464727248496
Pubmed

Nuclear targeting of proteins: how many different signals?

IPO5 KPNA6

9.99e-06364210822175
Pubmed

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.

FOXO3 FOXO6

9.99e-06364212857750
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

9.99e-06364231801062
Pubmed

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy.

DDX41 EFTUD2

9.99e-06364232703943
Pubmed

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.

CASKIN2 CASKIN1

9.99e-06364231727973
Pubmed

Karyopherins and nuclear import.

IPO5 KPNA6

9.99e-06364211751052
Pubmed

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein.

CASKIN2 CASKIN1

9.99e-06364212040031
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IPO5 MYBBP1A TRIO KALRN CASKIN1 IQSEC2 VPS35 MACF1 RIMBP2 CPNE4 UTRN VIRMA

1.02e-051431641237142655
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

MYBBP1A ATAD5 PHF14 KPNA6 MTREX DDX41 VIRMA EFTUD2

1.50e-0560564828977666
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

IPO5 MYBBP1A ATAD5 POLR1C PHF14 UFL1 MTREX DDX41 VIRMA SON

1.54e-051014641032416067
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

IPO5 NAA35 MYBBP1A ABCA2 COQ6 MACF1 UTRN EPG5 EFTUD2

1.64e-0580764930575818
Pubmed

The DNA sequence and analysis of human chromosome 6.

CCDC170 FOXO3 MMS22L USP45 POLR1C UFL1 DTNBP1 AKAP7

1.84e-0562264814574404
Pubmed

Treacher Collins syndrome: a clinical and molecular study based on a large series of patients.

POLR1C EFTUD2

2.00e-05464225790162
Pubmed

Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain.

FOXO3 FOXO6

2.00e-05464216326148
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MMS22L MYBBP1A VPS35 POLR1C UFL1 KPNA6 HERC1 MTREX DDX41 SON EFTUD2

2.05e-051284641117353931
Pubmed

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.

FOXO3 FOXO6 CLCN5

2.33e-053064328077597
Pubmed

Assembly of high order G alpha q-effector complexes with RGS proteins.

TRIO KALRN

3.32e-05564218936096
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

IPO5 TRIO KALRN MACF1 DTNBP1 UTRN SON

3.59e-0549764723414517
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

IPO5 MYBBP1A VPS35 POLR1C MACF1 UFL1 KPNA6 MTREX DDX41 SON EFTUD2

4.98e-051415641128515276
Pubmed

ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.

TRIO ANKRD62

4.98e-05664222666460
Pubmed

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins.

FOXO3 FOXO6

4.98e-05664221708191
Pubmed

FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.

FOXO3 FOXO6

4.98e-05664217974917
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

FOXO6 TRIO VPS35 MACF1 DTNBP1 SON

5.17e-0535864632460013
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

IPO5 MYBBP1A GUCY1B2 TRIO VPS35 UFL1 KPNA6 FGD5 MTREX DDX41 EFTUD2

5.30e-051425641130948266
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYBBP1A TRIO KALRN CASKIN1 IQSEC2 MACF1 RIMBP2 VIRMA EFTUD2

6.48e-0596364928671696
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

MYBBP1A INTS12 UFL1 HERC1 MTREX

6.86e-0523164536597993
Pubmed

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

MTREX EFTUD2

6.96e-05764230538148
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYBBP1A PHF14 UFL1 YY1AP1 DDX41 VIRMA SON EFTUD2

8.56e-0577464815302935
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

MYBBP1A INTS12 KPNA6 HERC1 MTREX UTRN EFTUD2

8.76e-0557364728330616
Pubmed

Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.

HAP1 ATXN3

9.27e-05864230994454
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

IPO5 MYBBP1A MACF1 MTREX DDX41 APBB1IP EFTUD2

9.65e-0558264720467437
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TRIO KALRN CASKIN1 IQSEC2 MACF1

1.01e-0425164527507650
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

IPO5 MYBBP1A MACF1 UFL1 MTREX DDX41 UTRN SON EFTUD2

1.03e-04102464924711643
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MACF1 RIMBP2 YY1AP1 VIRMA SON EPG5

1.05e-0440764612693553
Pubmed

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

IPO5 KPNA6

1.19e-04964210366569
Pubmed

HIV-1 nuclear import: in search of a leader.

IPO5 KPNA6

1.19e-04964210525473
Pubmed

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

IPO5 KPNA6

1.19e-04964210888652
Pubmed

HIV-1 nuclear import: in search of a leader.

IPO5 KPNA6

1.19e-0496429366553
Pubmed

HIV-1 infection requires a functional integrase NLS.

IPO5 KPNA6

1.19e-04964211389849
Pubmed

Changing expression and subcellular distribution of karyopherins during murine oogenesis.

IPO5 KPNA6

1.19e-04964226399853
Pubmed

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.

IPO5 KPNA6

1.19e-0496421631159
Pubmed

The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.

CPNE2 CPNE4

1.19e-0496429430674
Pubmed

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.

IPO5 KPNA6

1.19e-04964210860744
Pubmed

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.

IPO5 KPNA6

1.19e-0496429463369
Pubmed

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.

IPO5 KPNA6

1.19e-04964212414950
Pubmed

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells.

IPO5 KPNA6

1.19e-0496428105392
Pubmed

Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses.

IPO5 KPNA6

1.19e-04964211035935
Pubmed

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway.

IPO5 KPNA6

1.19e-0496429275210
Pubmed

Characterization of the nuclear import pathway for HIV-1 integrase.

IPO5 KPNA6

1.19e-04964211278458
Pubmed

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.

IPO5 KPNA6

1.19e-04964212368302
Pubmed

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.

FAM135B APBB1IP

1.49e-041064222228203
Pubmed

Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.

MYBBP1A POLR1C MTREX DDX41

1.52e-0414564427049334
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NAA35 MYBBP1A VPS35 POLR1C MACF1 MTREX DDX41 UTRN SON EFTUD2

1.72e-041353641029467282
Pubmed

HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr.

IPO5 KPNA6

1.81e-04116429562972
Pubmed

The functional interactome landscape of the human histone deacetylase family.

IPO5 TNRC18 KPNA6 DDX41 SON

1.95e-0428964523752268
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 MYBBP1A MACF1 MTREX UTRN VIRMA SON

1.96e-0465364722586326
Pubmed

Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon.

FOXO3 FOXO6

2.17e-041264228213137
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

MYBBP1A POLR1C MTREX DDX41 SON EFTUD2

2.25e-0446964637314180
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

NAA35 MYBBP1A TRIO KALRN CASKIN1 UFL1

2.41e-0447564631040226
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYBBP1A TNRC18 AMER1 INTS12 CLCN5 VPS35 COQ6 MACF1 PHF14 SLC4A3

2.86e-041442641035575683
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

MYBBP1A POLR1C MTREX DDX41 EFTUD2

2.95e-0431664531665637
Pubmed

The LIFEdb database in 2006.

SPATA7 PTGES2 VPS35 YY1AP1 CSTPP1 BGN DRC3

3.53e-0472064716381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

SPATA7 PTGES2 VPS35 YY1AP1 CSTPP1 BGN DRC3

3.59e-0472264715489336
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

IPO5 TNRC18 TRIO MACF1 SON

3.70e-0433264537433992
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

MACF1 UTRN SON

3.80e-047664327542412
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

INTS12 ATAD5 POLR1C MACF1 PHF14 UFL1 MTREX UTRN VIRMA SON

3.85e-041497641031527615
Pubmed

Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain.

FOXO3 FOXO6

3.93e-041664216376864
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

IPO5 MYBBP1A YY1AP1 MTREX EFTUD2

4.07e-0433964530415952
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

MYBBP1A YY1AP1 KPNA6 MTREX DDX41

4.18e-0434164532971831
Pubmed

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

MTREX DDX41 EFTUD2

4.41e-048064311991638
Pubmed

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.

IPO5 CPNE2 MTREX EFTUD2

4.42e-0419264432176739
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

SPATA7 MYBBP1A VPS35 YY1AP1 DTNBP1 CSTPP1 DRC3

4.51e-0475064711230166
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MYBBP1A ATAD5 POLR1C MACF1 MTREX VIRMA SON

4.84e-0475964735915203
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

MACF1 MTREX UTRN VIRMA

4.86e-0419764420811636
Pubmed

The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.

INTS12 MTREX EFTUD2

5.09e-048464326299517
Pubmed

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.

IPO5 UFL1 KPNA6 DTNBP1

5.25e-0420164434917906
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

KPNA6 MTREX VIRMA SON EFTUD2

5.41e-0436164530344098
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

IPO5 MMS22L MYBBP1A UTRN EFTUD2

5.55e-0436364514691545
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MYBBP1A INTS12 ATAD5 POLR1C PHF14 MTREX DDX41 SON EFTUD2

5.80e-04129464930804502
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

ANKRD62 MACF1

6.20e-042064221689717
Pubmed

Recruitment of the human TREX complex to mRNA during splicing.

VIRMA EFTUD2

6.20e-042064215998806
Pubmed

DNA cloning using in vitro site-specific recombination.

SPATA7 PTGES2 VPS35 YY1AP1 CSTPP1 BGN DRC3

6.32e-0479464711076863
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

MYBBP1A VPS35 POLR1C KPNA6 MTREX EFTUD2

6.39e-0457164637167062
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYBBP1A TRIO CASKIN2 ATAD5 KPNA6 HERC1 DTNBP1 UTRN

6.62e-04104964827880917
Pubmed

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

MYBBP1A TRIO MTREX SON

6.75e-0421564430462309
Pubmed

Identification of cellular proteins required for replication of human immunodeficiency virus type 1.

KALRN HAP1

6.84e-042164222404213
Pubmed

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.

MYBBP1A MTREX

6.84e-042164224923560
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

IPO5 MYBBP1A MACF1 DDX41 VIRMA SON EFTUD2

6.95e-0480764722681889
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

IPO5 MYBBP1A ABCA2 AMER1 VPS35 POLR1C KPNA6 MTREX EFTUD2

7.25e-04133564929229926
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

MYBBP1A MTREX SON EFTUD2

7.35e-0422064435785414
InteractionYWHAH interactions

FOXO3 ABCA2 AMER1 INTS12 FOXO6 TRIO CASKIN2 IQSEC2 MACF1 PLEKHM3 HERC1 MTREX UTRN VIRMA DNAH7 EFTUD2

1.84e-0711026316int:YWHAH
InteractionKALRN interactions

TRIO KALRN IQSEC2 MACF1 DTNBP1 VIRMA

5.45e-0796636int:KALRN
InteractionFOXO3B interactions

FOXO3 FOXO6 VIRMA

5.78e-076633int:FOXO3B
InteractionYWHAG interactions

FOXO3 AMER1 FOXO6 CASKIN2 IQSEC2 MACF1 PLEKHM3 MTREX DDX41 UTRN VIRMA DNAH7 SON EFTUD2

2.42e-0512486314int:YWHAG
InteractionH2AC4 interactions

IPO5 MMS22L MYBBP1A ATAD5 PHF14 UFL1 KPNA6 DDX41 VIRMA

2.62e-05506639int:H2AC4
InteractionRPL31 interactions

IPO5 NAA35 MYBBP1A ATAD5 MACF1 UFL1 MTREX DDX41 VIRMA EFTUD2

4.55e-056806310int:RPL31
InteractionPSMD13 interactions

IPO5 FOXO3 ATXN3 UFL1 FGD5 VIRMA EFTUD2

4.64e-05306637int:PSMD13
InteractionABCF2 interactions

PTGES2 TNRC18 POLR1C UFL1 VIRMA EFTUD2

4.81e-05209636int:ABCF2
InteractionCSE1L interactions

IPO5 ATXN3 UFL1 KPNA6 MTREX VIRMA EFTUD2

5.46e-05314637int:CSE1L
InteractionCDC5L interactions

IPO5 MYBBP1A TRIO KALRN MACF1 UFL1 MTREX DDX41 VIRMA SON EFTUD2

6.14e-058556311int:CDC5L
CytobandEnsembl 112 genes in cytogenetic band chr6q16

MMS22L USP45 UFL1

6.79e-0556643chr6q16
Cytoband6q16.1

MMS22L UFL1

2.89e-04186426q16.1
GeneFamilyCopines

CPNE2 CPNE4

2.25e-049462829
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO KALRN FGD5

6.30e-0466463722
GeneFamilyArmadillo repeat containing|Importins

IPO5 KPNA6

9.44e-0418462596
CoexpressionGSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN

MMS22L USP45 ATAD5 CEP57L1 PHF14 CSTPP1

9.50e-06200646M7861
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SERPING1 UTRN SLC4A3 BGN

6.44e-06182645ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SERPING1 UTRN SLC4A3 BGN

6.79e-0618464594748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SERPING1 UTRN SLC4A3 BGN

6.79e-06184645819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

MACF1 HERC1 UTRN BGN

4.28e-05135644ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATAD5 OR6Y1 HERC1 APBB1IP

7.70e-05157644a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|metastatic_Brain / Location, Cell class and cell subclass

PDE1A USP45 SERPING1 BGN

9.56e-051666440da2c6ea1e62f1aafabafbbfbbcc6f7011739346
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 SERPING1 MACF1 BGN

1.05e-04170644e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

HAP1 CIB4 ANKRD62 BGN

1.07e-04171644080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 HAP1 ANKRD62 RIMBP2

1.42e-041846448fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A CIB4 SERPING1 BGN

1.45e-0418564498547c1b1828b76da810ed86082182afaaacdb3f
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A CIB4 SERPING1 BGN

1.45e-041856445f5df92b328be396941b5812d00454b5ff927d30
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXO3 PDE1A CIB4 SERPING1

1.48e-04186644d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KALRN CASKIN2 FGD5 CPNE4

1.48e-04186644a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN CIB4 ANKRD62 BGN

1.51e-0418764486250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

MACF1 HERC1 UTRN EPG5

1.54e-04188644ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS35 SERPING1 MACF1 MTREX

1.57e-041896446dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS35 SERPING1 MACF1 MTREX

1.57e-041896443ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR1 HAP1 SERPING1 CPNE4

1.57e-04189644fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

HAP1 CIB4 ANKRD62 BGN

1.57e-04189644d7ed96add29f219183c802895fbff519b627f635
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS35 SERPING1 MACF1 MTREX

1.57e-04189644875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS35 SERPING1 MACF1 MTREX

1.57e-0418964497ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 KALRN UTRN BGN

1.64e-0419164404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 MACF1 APBB1IP BGN

1.71e-0419364406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR1 KALRN CPNE4 SLC4A3

1.71e-04193644be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR1 KALRN CPNE4 SLC4A3

1.71e-041936440c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR1 KALRN CPNE4 SLC4A3

1.71e-041936448689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 MACF1 APBB1IP BGN

1.71e-041936449c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell368C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDE1A ATAD5 CEP57L1 VIRMA

1.71e-041936445f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 MACF1 APBB1IP BGN

1.71e-04193644a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 MACF1 APBB1IP BGN

1.71e-04193644b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A CLCN5 DNAH7 CSTPP1

1.77e-041956446477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 MACF1 UFL1 APBB1IP

1.77e-04195644a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE1A SERPING1 PHF14 BGN

1.84e-04197644ad6c200a193a15360d17463e18a465ce1b90b8da
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CASKIN2 FGD5 UTRN

1.88e-0419864431ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CASKIN2 FGD5 UTRN

1.88e-041986440a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE1A FOXO6 IQSEC2 UTRN

1.92e-04199644121de4e02585de3a3010398387c523bacf8ce546
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CCDC170 MMS22L DNAH7 DRC3

1.92e-0419964415f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TRIO MACF1 UTRN SON

1.95e-04200644dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CIB4 SERPING1 ANKRD62 BGN

1.95e-04200644600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CIB4 SERPING1 ANKRD62 BGN

1.95e-042006448158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SERPING1 MACF1 UTRN SON

1.95e-0420064412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 HAP1 APBB1IP

8.07e-04127643f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA2 COQ6 DRC3

8.26e-041286432cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

PLEKHM3 SLC4A3 CSTPP1

9.22e-04133643e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

MROH2B SERPING1 BGN

1.00e-03137643dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 APBB1IP AKAP7

1.05e-031396439e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 SERPING1 BGN

1.16e-03144643121853910eeea1ea0642b3cc99f9200015480368
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE1A HAP1 BGN

1.25e-03148643e514b7cf412ddbee249894e089e2204c67bcdbce
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.25e-03148643d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.25e-03148643c8e93b87212f55774223caa385859c566fa1981f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KALRN PLEKHM3 APBB1IP

1.33e-03151643b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MACF1 DNAH7 FAM135B

1.33e-03151643b545823113a3450c5f841f7de48bf0937593544f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MACF1 DNAH7 FAM135B

1.33e-031516430cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLCN5 SLC4A3 CSTPP1

1.38e-0315364391e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLCN5 SLC4A3 CSTPP1

1.38e-03153643f17f62646633cf95c810dcd5328978058741b276
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.41e-031546437556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.41e-031546434e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.41e-0315464358072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.41e-031546439ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASKIN1 RIMBP2 CPNE4

1.43e-03155643498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.43e-031556435f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH7 DRC3

1.43e-031556430944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEP57L1 UTRN EFTUD2

1.43e-03155643d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CPNE2 KALRN FGD5

1.46e-03156643ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA2 USP45 SERPING1

1.54e-031596437ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1A MMS22L BGN

1.54e-031596437ed659163f45e0c4df4782997c0786900c8186c8
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE1A AMER1 TRPC5OS

1.60e-0316164346b5d80d2d521fb69752aba4c10383e715a32002
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KALRN FGD5 CPNE4

1.63e-031626431f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLCN5 ATXN3 PLEKHM3

1.65e-0316364363b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 FGD5 APBB1IP

1.65e-03163643ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SERPING1 BGN DRC3

1.65e-03163643e393e5ff885a42b2b44e430d3d5a58f5e50eb732
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KALRN FGD5 CPNE4

1.65e-03163643c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1B2 TRIO APBB1IP

1.68e-031646430853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IPO5 TNRC18 DNAH7

1.71e-03165643436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IPO5 TNRC18 DNAH7

1.71e-03165643242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellEndothelial-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

PDE1A KALRN BGN

1.71e-0316564310087d8bd2985906ef19547fe77eb178ae5e1638
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CASKIN2 PLEKHM3 SLC4A3

1.74e-03166643b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

HAP1 SLC4A3 DRC3

1.77e-03167643bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CASKIN2 PLEKHM3 SLC4A3

1.77e-03167643e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO3 CLCN5 ATAD5

1.77e-03167643f5bffa77061baec0ba87bd688a047595f32534db
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CLCN5 HAP1 SLC4A3

1.80e-03168643968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellmild_COVID-19_(asymptomatic)-RBC|World / disease group, cell group and cell class (v2)

PI4K2B ANKRD62 VIRMA

1.83e-031696432bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 CPNE4 BGN

1.83e-03169643335619507857383c3b0b507cdf05d786ed59e585
ToppCellfacs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA7 MMS22L COQ6

1.83e-031696432a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH7 DRC3

1.83e-0316964314aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXO6 SERPING1 BGN

1.83e-03169643031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXO6 RIMBP2 CPNE4

1.86e-0317064302f0be0aab8ba2d35a83238609352ef3677511c9
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HAP1 ANKRD62 RIMBP2

1.86e-03170643fcaa32607bcbd8be6f040f9487c3d71e976e1077
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPNE2 HAP1 FGD5

1.86e-0317064336dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE1A SERPING1 BGN

1.86e-031706437653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPNE2 HAP1 FGD5

1.90e-03171643a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPNE2 HAP1 FGD5

1.90e-03171643f6047dee2be0b09ad4d48f97369111bc92e89b35
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXO6 SERPING1 BGN

1.90e-0317164315cb4670ff4234ac46aea8a5911138d6913c4482
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MACF1 HERC1 UTRN

1.90e-031716432e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

PDE1A KALRN UTRN

1.90e-03171643e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 IQSEC2 PHF14

1.93e-03172643b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA7 PDE1A HAP1

1.93e-03172643574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 IQSEC2 PHF14

1.93e-031726432f1673fcb2356684d60871debb0f159aec553a1c
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CPNE2 CEP57L1 EPG5

1.93e-03172643a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 FGD5 BGN

1.93e-03172643a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
DiseaseTreacher Collins syndrome (implicated_via_orthology)

POLR1C EFTUD2

6.27e-056612DOID:2908 (implicated_via_orthology)
Diseaseglucagon measurement, glucose tolerance test

MACF1 HERC1

6.27e-056612EFO_0004307, EFO_0008463
Diseasesexual dimorphism measurement

FOXO3 FOXO6 ATAD5 CASKIN1 ATXN3 MACF1 HERC1 AKAP7 CSTPP1

4.25e-041106619EFO_0021796
Diseaseblood phosphate measurement

CCDC170 FOXO3 CPNE4 AKAP7

4.69e-04174614EFO_0010972
Diseasetemporal lobe epilepsy (is_marker_for)

FOXO3 DTNBP1

7.80e-0420612DOID:3328 (is_marker_for)
DiseaseLeber Congenital Amaurosis

SPATA7 USP45

9.46e-0422612C0339527
DiseaseParkinson disease

VPS35 ATXN3

9.46e-0422612cv:C0030567
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

FOXO3 PDE1A FOXO6 CPNE4 HERC1 UTRN FAM135B

1.29e-03801617EFO_0003888, EFO_0007052, MONDO_0002491
Diseasecerebral infarction (is_implicated_in)

KALRN SERPING1

1.65e-0329612DOID:3526 (is_implicated_in)
Diseaseintelligence, self reported educational attainment

FOXO3 MMS22L FOXO6

1.85e-03117613EFO_0004337, EFO_0004784

Protein segments in the cluster

PeptideGeneStartEntry
LNSLSEFMDNMSFLD

ATAD5

1646

Q96QE3
EFMDNMSFLDALLTD

ATAD5

1651

Q96QE3
EDNSDMIFMLLTKFD

EPG5

1756

Q9HCE0
AEAQMLGSADLDDMK

SLC4A3

256

P48751
DFAAMEFLDGDSRML

CPNE2

476

Q96FN4
EFEANTMDSLVDMPF

AKAP7

26

Q9P0M2
EDIDQMFSTLLGEMD

APBB1IP

6

Q7Z5R6
SDDENFMLLIEQSGM

ANKRD62

396

A6NC57
EALIMFDKDNLDDMG

COQ6

126

Q9Y2Z9
LFQSDAMFEPDMQEA

AMER1

721

Q5JTC6
FLEDMDSLEDMALLE

CDR1

81

P51861
FEETSADDFAMEMGL

INTS12

146

Q96CB8
GSMFDDLADQLDAML

CASKIN1

1416

Q8WXD9
INEEAAMFDSLLMDS

KPNA6

56

O60684
DAAADFTLLAMDMPS

MMS22L

741

Q6ZRQ5
MDFSSMDLDDALRKF

IQSEC2

826

Q5JU85
LGSDLGDAMSEEDML

ATXN3

326

P54252
EIDLDDEAMEAMFGQ

HERC1

2931

Q15751
TMALMEEFFLQGDKE

PDE1A

381

P54750
DFTLDDGPFMMNDEE

BGN

26

P21810
MDLMDISDQEALDVF

DTNBP1

241

Q96EV8
LDFHGAVMRALDDMD

FGD5

916

Q6ZNL6
ESIILNDFMDSDEMD

FOXO6

451

A8MYZ6
AMHVSMLEGFDENLD

KALRN

1456

O60229
LNMDESLEEACTMFE

PLEKHM3

741

Q6ZWE6
LALDEADRMIDMGFE

DDX41

341

Q9UJV9
ALLDTQDMENMSDDD

IPO5

641

O00410
LLDFVSMEELNDMDD

PHF14

191

O94880
ISTMFDALADQLDAM

CASKIN2

1186

Q8WXE0
MFSQLADLDDELDGM

MACF1

5136

Q9UPN3
LGDEAMMALDQSLAS

MYBBP1A

781

Q9BQG0
EMNAFLDDPEFADIM

PI4K2B

96

Q8TCG2
MDDAMDCLMSFSDFL

CSTPP1

126

Q9H6J7
DFSDMQMLDGDDGIL

CPNE4

476

Q96A23
FEAEEGLMLAADIMR

HAP1

536

P54257
SDEDLMDIPATAMDF

CLCN5

26

P51795
LMNLIDCFMDDFADE

DNAH7

1816

Q8WXX0
NDGMVEADDLRSLMF

DNAH7

2256

Q8WXX0
EGDDFNLLLAVTMLM

ABCA2

886

Q9BZC7
SQDMLSIMEKLEFFD

SERPING1

406

P05155
DNLSELLMAMQDELD

CEP57L1

321

Q8IYX8
DQMAAELGFDMRLDV

CCDC170

446

Q8IYT3
ADISELFDALMTLEM

DRC3

356

Q9H069
MDTFADFDTMTDRLL

FAM135B

1181

Q49AJ0
LDLDMFNGSLECDME

FOXO3

611

O43524
LQGAMDDLDADMKEA

UTRN

2696

P46939
ADDEEMMDQLLRQGF

RIMBP2

916

O15034
DFFDIDVIMDILDMN

GUCY1B2

76

O75343
LRVMEGLDAFDDLMQ

PTGES2

341

Q9H7Z7
MDENSLEFDMVGIDA

POLR1C

56

O15160
LMFLEEMLDGLESLN

MROH2B

1006

Q7Z745
DASQAEMVDFFLALM

OR6Y1

196

Q8NGX8
NSDDMSEDLLMDLTN

CIB4

131

A0PJX0
SSLEDMDALELDFRM

TNRC18

1471

O15417
LMESMAAEEDFEPNQ

TNRC18

2111

O15417
ENLEMNGDSLMFASL

USP45

461

Q70EL2
SSADELLLTEMMFNG

MTREX

881

P42285
DKLFGLFEAMSAIEM

NAA35

51

Q5VZE5
ISDSMDFVLLNFAEM

VPS35

176

Q96QK1
DLIFDIDQAMLDMDN

TRPC5OS

81

A6NMA1
IEDDMLKEEMNGFSS

SPATA7

131

Q9P0W8
LMEDLFETFQDEMGF

YY1AP1

66

Q9H869
MDFLADLMDNSELIR

EFTUD2

116

Q15029
MAVDSAMELLFLDTF

VIRMA

1

Q69YN4
RLSENAFDLEAMSML

SON

2236

P18583
FNFLASDLMMAVDDP

UFL1

586

O94874
DAMHLSMLEGFDENI

TRIO

1466

O75962