Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	2.07e-14	431	110	21	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8I2 OR8J3 OR8U1 OR10J3 OR5K4 OR8J1 OR10R2 OR10J1 OR10Z1 OR8U8 OR10K2 OR5F1	5.36e-12	127	110	12	GO:0005549
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 FZD3 OR2T35 OR13C5 OR13C8 OR10J3 GPR143 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	1.03e-11	884	110	25	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 FZD3 OR2T35 OR13C5 OR13C8 OR10J3 GPR143 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 CLEC12A OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 EDAR P2RY4 PTCH2 OR10K2 OR5F1	6.85e-10	1353	110	28	GO:0004888
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	1.40e-14	432	111	21	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	5.93e-14	465	111	21	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	1.34e-13	485	111	21	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	5.97e-13	524	111	21	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	1.36e-12	547	111	21	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	4.40e-12	582	111	21	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 PIEZO1 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	3.45e-11	722	111	22	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 GPR143 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 CDC14A OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 LRP2 OR10K2 RPGR NIPBL OR5F1	6.72e-11	1072	111	26	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 FZD3 OR2T35 OR13C5 OR13C8 OR10J3 GPR143 OR5K4 OR2T1 OR2T2 APLP2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	1.76e-08	1395	111	26	GO:0007186
Domain	Olfact_rcpt	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	5.56e-15	393	106	21	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	2.71e-12	670	106	23	IPR017452
Domain	7tm_1	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	3.35e-12	677	106	23	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	4.25e-12	685	106	23	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	5.08e-12	691	106	23	PS50262
Domain	GPCR_Rhodpsn	OR8I2 CXCR3 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 P2RY4 OR10K2 OR5F1	5.23e-12	692	106	23	IPR000276
Domain	-	PMS1 EFL1 GALK2	2.19e-04	21	106	3	3.30.230.10
Domain	Ribosomal_S5_D2-typ_fold_subgr	PMS1 EFL1 GALK2	2.53e-04	22	106	3	IPR014721
Domain	EF-hand_Ca_insen	ACTN4 ACTN1	4.72e-04	6	106	2	IPR014837
Domain	Liprin	PPFIA4 PPFIA1	4.72e-04	6	106	2	IPR029515
Domain	EFhand_Ca_insen	ACTN4 ACTN1	4.72e-04	6	106	2	PF08726
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	2.46e-13	417	93	21	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR8I2 OR8J3 OR8U1 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR5K4 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR8U8 OR10J5 OR2T6 SCN2B LRP2 OR10K2 OR5F1	1.44e-11	636	93	23	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8I2 OR8J3 OR8U1 OR2T27 OR13C5 OR13C8 OR10J3 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR10Z1 OR8U8 OR10J5 OR2T6 OR10K2 OR5F1	6.39e-11	389	93	18	M14091
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8I2 OR8J3 OR8U1 OR2T35 OR13C8 OR10J3 OR5K4 OR2T1 OR8J1 OR10J1 OR6P1 OR10Z1 OR10J5 OR2T6 OR10K2	3.05e-13	340	111	15	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8I2 OR8J3 OR8U1 OR2T35 OR13C8 OR10J3 OR5K4 OR2T1 OR8J1 OR10J1 OR6P1 OR10Z1 OR10J5 OR2T6 OR10K2	3.05e-13	340	111	15	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8I2 OR8J3 OR8U1 OR2T35 OR13C8 OR10J3 OR5K4 OR2T1 OR8J1 OR10J1 OR6P1 OR10Z1 OR10J5 OR2T6 OR10K2	3.46e-13	343	111	15	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8I2 OR8J3 OR8U1 OR2T35 OR13C8 OR10J3 OR5K4 OR2T1 OR8J1 OR10J1 OR6P1 OR10Z1 OR10J5 OR2T6 OR10K2	3.92e-13	346	111	15	14611657
Pubmed	The human olfactory receptor gene family.	OR8I2 OR8J3 OR2T27 OR2T35 OR13C5 OR13C8 OR10J3 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR6P1 OR10Z1 OR10J5 OR10K2 OR5F1	1.69e-12	541	111	17	14983052
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR8I2 OR8J3 OR13C8 OR10J3 OR2T1 OR2T2 OR8J1 OR10R2 OR10J1 OR2T6 OR5F1	1.31e-10	219	111	11	12213199
Pubmed	p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains.	WNT11 BLK CTR9	3.15e-07	5	111	3	8636124
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS1 EFL1 PPFIA1 APLP2 NBEA ACTN4 CDC14A SBF1 P4HA1 CTR9 NAT10 OTUD4 SLFN11 PEAK1	6.58e-06	1049	111	14	27880917
Pubmed	Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.	ACTN4 ACTN1	1.01e-05	2	111	2	34010028
Pubmed	An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.	ACTN4 ACTN1	1.01e-05	2	111	2	23557398
Pubmed	BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome.	BRD4 NIPBL	1.01e-05	2	111	2	29379197
Pubmed	Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.	ACTN4 ACTN1	1.01e-05	2	111	2	20037648
Pubmed	HAMLET binding to α-actinin facilitates tumor cell detachment.	ACTN4 ACTN1	1.01e-05	2	111	2	21408150
Pubmed	Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.	ACTN4 ACTN1	1.01e-05	2	111	2	28797528
Pubmed	α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.	ACTN4 ACTN1	1.01e-05	2	111	2	23454549
Pubmed	Cdc14: a highly conserved family of phosphatases with non-conserved functions?	CDC14C CDC14A	1.01e-05	2	111	2	20720150
Pubmed	The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes.	BRD4 NIPBL	1.01e-05	2	111	2	31320616
Pubmed	Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.	ACTN4 ACTN1	1.01e-05	2	111	2	20156433
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR2T27 OR2T35 OR2T2 OR6P1	1.45e-05	46	111	4	32126975
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	UBE4B PPFIA1 TRRAP P4HA1 FAR1	2.16e-05	104	111	5	31240132
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	WWP1 STK32C LCK MAP3K6 BLK PASK KLHL23 SLFN11	2.69e-05	372	111	8	22939624
Pubmed	Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.	OR10J3 OR10J1 OR10J5	2.95e-05	19	111	3	22939635
Pubmed	FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.	WNT11 LCK BLK	2.95e-05	19	111	3	23616926
Pubmed	Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.	ACTN4 ACTN1	3.02e-05	3	111	2	16751418
Pubmed	α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.	ACTN4 ACTN1	3.02e-05	3	111	2	21784188
Pubmed	Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.	ACTN4 ACTN1	3.02e-05	3	111	2	23890175
Pubmed	Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing γδ T cells.	LCK BLK	3.02e-05	3	111	2	20974990
Pubmed	Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.	CDC14C CDC14A	3.02e-05	3	111	2	26283732
Pubmed	Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination.	LCK BLK	3.02e-05	3	111	2	10449731
Pubmed	Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.	ACTN4 ACTN1	3.02e-05	3	111	2	16951376
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	UBE4B WWP1 PIEZO1 RNPEPL1 STK32C TRRAP TBC1D9 MYOF TMEM129 SBF1 BRD4 NFKB2 ANKRD16	5.29e-05	1105	111	13	35748872
Pubmed	CDC14A phosphatase is essential for hearing and male fertility in mouse and human.	CDC14C CDC14A	6.03e-05	4	111	2	29293958
Pubmed	BRD4 orchestrates genome folding to promote neural crest differentiation.	BRD4 NIPBL	6.03e-05	4	111	2	34611363
Pubmed	Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.	ACTN4 ACTN1	6.03e-05	4	111	2	23515331
Pubmed	Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.	ACTN4 ACTN1	6.03e-05	4	111	2	1629252
Pubmed	An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.	ACTN4 ACTN1	6.03e-05	4	111	2	2116421
Pubmed	Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.	ACTN4 ACTN1	6.03e-05	4	111	2	22351778
Pubmed	CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.	ACTN4 ACTN1	6.03e-05	4	111	2	10753915
Pubmed	Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.	ACTN4 ACTN1	6.03e-05	4	111	2	16807302
Pubmed	Interactions of a hemidesmosome component and actinin family members.	ACTN4 ACTN1	6.03e-05	4	111	2	11739652
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	ACTN4 ACTN1	6.03e-05	4	111	2	15988023
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR8J3 OR2T35 OR10J3 OR8J1	9.52e-05	74	111	4	15081110
Pubmed	Gut commensal bacteria and regional Wnt gene expression in the proximal versus distal colon.	FZD3 WNT11	1.00e-04	5	111	2	24418259
Pubmed	Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.	ACTN4 ACTN1	1.00e-04	5	111	2	15841212
Pubmed	The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.	ACTN4 ACTN1	1.00e-04	5	111	2	12837758
Pubmed	Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.	ACTN4 ACTN1	1.00e-04	5	111	2	19943616
Pubmed	TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles.	FZD3 BLK	1.00e-04	5	111	2	10764796
Pubmed	The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.	ACTN4 ACTN1	1.00e-04	5	111	2	16501493
Pubmed	The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.	PPFIA4 PPFIA1	1.00e-04	5	111	2	19013515
Pubmed	Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.	RAN ACTN4 ACTN1 MYOF FAM120C	1.32e-04	152	111	5	16009940
Pubmed	Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.	ACTN4 ACTN1	1.50e-04	6	111	2	18425115
Pubmed	Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm.	RASGRF1 LCK	1.50e-04	6	111	2	11389730
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ACTN4 ACTN1	1.50e-04	6	111	2	22693585
Pubmed	Cornelia de Lange Syndrome	BRD4 NIPBL	1.50e-04	6	111	2	20301283
Pubmed	Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.	PPFIA4 PPFIA1	1.50e-04	6	111	2	21618221
Pubmed	The protein-tyrosine phosphatase SHP-1 regulates the phosphorylation of alpha-actinin.	ACTN4 ACTN1	1.50e-04	6	111	2	15070900
Pubmed	Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.	LCK BLK	1.50e-04	6	111	2	2404338
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	FZD3 WNT11 LRP2	1.92e-04	35	111	3	30940800
Pubmed	Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.	RAN HSP90B2P MYOF CSNK2B	1.95e-04	89	111	4	27034005
Pubmed	Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.	ACTN4 ACTN1	2.10e-04	7	111	2	11724819
Pubmed	Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2.	RAN IPO11	2.10e-04	7	111	2	11032817
Pubmed	Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.	PPFIA4 PPFIA1	2.10e-04	7	111	2	11931740
Pubmed	Proline-rich sequences that bind to Src homology 3 domains with individual specificities.	LCK BLK	2.10e-04	7	111	2	7536925
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ACADSB OR2T1 NBEA NHP2 DNAH7 OTUD4 SLFN11 GFPT2 NIPBL	2.14e-04	638	111	9	31182584
Pubmed	RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.	HSP90B2P SLC44A2 ACTN4 PAIP1	2.21e-04	92	111	4	23055941
Pubmed	Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).	ACTN4 ACTN1 FAR1	2.27e-04	37	111	3	16396496
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	WWP1 PPFIA1 TRRAP PASK P4HA1 FAM120C CSNK2B BRD4 NAT10 LRP2 SLFN11 FAR1	2.40e-04	1116	111	12	31753913
Pubmed	Phosphorylation of SOCS1 Inhibits the SOCS1-p53 Tumor Suppressor Axis.	LCK BLK	2.79e-04	8	111	2	31101761
Pubmed	Mice deficient in alpha-actinin-4 have severe glomerular disease.	ACTN4 ACTN1	2.79e-04	8	111	2	12782671
Pubmed	BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.	FBXW8 NFKB2	2.79e-04	8	111	2	20558726
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	ACTN4 ACTN1	2.79e-04	8	111	2	20215401
Pubmed	Chemerin, a novel adipokine in the regulation of angiogenesis.	OR10J3 OR10J1	2.79e-04	8	111	2	20237162
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RAN HSP90B2P PPFIA1 APLP2 ACTN4 CDC14A PASK SBF1 CTR9 RIMOC1 FAR1	2.91e-04	974	111	11	28675297
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PIEZO1 PPFIA1 APLP2 ACTN1 NHP2 TRRAP MYOF SBF1 P4HA1 FAM120C CTR9 OTUD4 FAR1 NIPBL	3.00e-04	1497	111	14	31527615
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	ACTN1 TRRAP CSNK2B BRD4 NAT10 FAHD1 NIPBL IPO11	3.21e-04	533	111	8	30554943
Pubmed	Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import.	RAN IPO11	3.58e-04	9	111	2	15545318
Pubmed	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.	PPFIA4 PPFIA1	3.58e-04	9	111	2	12923177
Pubmed	The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse.	OR13C8 OR10J5	3.58e-04	9	111	2	32209480
Pubmed	Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.	PPFIA4 PPFIA1	3.58e-04	9	111	2	12629171
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RAN UBE4B ACTN4 ACTN1 NHP2 TRRAP SBF1 CTR9 CSNK2B NFKB2 NAT10 FAR1 NIPBL	3.86e-04	1353	111	13	29467282
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	ACTN4 ACTN1	4.47e-04	10	111	2	20368620
Pubmed	Expression of tyrosine kinase gene in mouse thymic stromal cells.	LCK BLK	4.47e-04	10	111	2	8943574
Pubmed	Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.	GPD1 WNT11	4.47e-04	10	111	2	18604206
Pubmed	Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.	GPD1 LCK	4.47e-04	10	111	2	8406449
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	ACTN4 ACTN1 MYOF	5.24e-04	49	111	3	21362503
Pubmed	Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex.	FZD3 WNT11	5.45e-04	11	111	2	18606138
Pubmed	Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11.	RAN IPO11	5.45e-04	11	111	2	11809816
Pubmed	Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL.	WWP1 LCK	5.45e-04	11	111	2	34831026
Pubmed	Cloning, central nervous system expression and chromosomal mapping of the mouse PAK-1 and PAK-3 genes.	WNT11 CTR9	5.45e-04	11	111	2	10352232
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	ACTN4 ACTN1 COG6 CSNK2B	5.70e-04	118	111	4	21078624
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	PPFIA1 ACTN4 PASK NFKB2 PEAK1	5.71e-04	209	111	5	36779422
Pubmed	WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.	UBE4B MAP3K6 ANKRD16	6.24e-04	52	111	3	30655611
Pubmed	Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.	ACTN4 ABCB8 OTUD4	6.24e-04	52	111	3	23182705
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C8	6.52e-04	12	111	2	12906860
Pubmed	p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase.	LCK BLK	6.52e-04	12	111	2	8621719
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PPFIA4 PPFIA1	6.52e-04	12	111	2	9624153
Pubmed	Identification of ligands for olfactory receptors by functional expression of a receptor library.	OR8U1 OR2T1	6.52e-04	12	111	2	9875846
Pubmed	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.	ACTN4 ACTN1	6.52e-04	12	111	2	15465019
Pubmed	The chromosomal distribution of mouse odorant receptor genes.	HSP90B2P WNT11 OR10J5	6.97e-04	54	111	3	8570653
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	WWP1 PPFIA1 ACTN4 CTR9 NAT10 IRAK4 LRP2 OTUD4 HSD3B1 GFPT2 PEAK1	7.10e-04	1084	111	11	11544199
Cytoband	Ensembl 112 genes in cytogenetic band chr1q23	OR10J3 OR10R2 OR10J1 OR6P1 OR10Z1 OR10J5 OR10K2	1.40e-06	226	111	7	chr1q23
Cytoband	1q23.1	OR10R2 OR6P1 OR10Z1 OR10K2	4.88e-06	46	111	4	1q23.1
Cytoband	1q44	OR2T27 OR2T35 OR2T1 OR2T2 OR2T6	7.54e-06	110	111	5	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2T27 OR2T35 OR2T1 OR2T2 OR2T6	1.58e-05	128	111	5	chr1q44
Cytoband	11q12.1	OR8I2 OR8J3 OR8U1 OR8J1 OR5F1	4.73e-05	161	111	5	11q12.1
Cytoband	1q23.2	OR10J3 OR10J1 OR10J5	8.51e-05	35	111	3	1q23.2
Cytoband	Xq13	CXCR3 P2RY4	4.44e-04	13	111	2	Xq13
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR8I2 OR8J3 OR8U1 OR8J1 OR5F1	1.56e-03	345	111	5	chr11q12
Cytoband	4q31.21	TBC1D9 OTUD4	1.81e-03	26	111	2	4q31.21
Cytoband	10q24	MYOF NFKB2	3.27e-03	35	111	2	10q24
Cytoband	22q13.33	SBF1 MLC1	3.85e-03	38	111	2	22q13.33
Cytoband	9q31.1	OR13C5 OR13C8	4.47e-03	41	111	2	9q31.1
GeneFamily	Olfactory receptors, family 10	OR10J3 OR10R2 OR10J1 OR10Z1 OR10J5 OR10K2	4.91e-07	66	81	6	157
GeneFamily	Olfactory receptors, family 8	OR8I2 OR8J3 OR8U1 OR8J1 OR8U8	2.60e-06	49	81	5	155
GeneFamily	Actinins	ACTN4 ACTN1	1.18e-04	4	81	2	1112
GeneFamily	Olfactory receptors, family 2	OR2T27 OR2T35 OR2T1 OR2T2 OR2T6	1.53e-04	113	81	5	149
Drug	PHA-00767505E [723337-45-9]; Down 200; 10uM; MCF7; HT_HG-U133A	B3GALNT1 UBE4B TRRAP CDC14A MYOF SBF1 NFKB2 PEAK1	5.25e-06	197	110	8	6550_DN
Drug	Mesalamine [89-57-6]; Down 200; 26.2uM; PC3; HT_HG-U133A	EFL1 ABHD18 ACTN1 CDC14A SBF1 ATP2C2 IRAK4 GFPT2	5.66e-06	199	110	8	5888_DN
Disease	Congenital muscular hypertrophy-cerebral syndrome	BRD4 NIPBL	1.11e-04	5	99	2	C1802395
Disease	Cornelia de Lange Syndrome 3	BRD4 NIPBL	1.11e-04	5	99	2	C1853099
Disease	Cornelia de Lange Syndrome 1	BRD4 NIPBL	1.11e-04	5	99	2	C4551851
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN4 ACTN1	1.11e-04	5	99	2	DOID:0111128 (implicated_via_orthology)
Disease	De Lange syndrome	BRD4 NIPBL	1.66e-04	6	99	2	cv:C0270972
Disease	Cornelia De Lange Syndrome	BRD4 NIPBL	3.08e-04	8	99	2	C0270972
Disease	Congenital Heart Defects	TRRAP BRD4 NIPBL	4.39e-04	44	99	3	C0018798
Disease	rheumatoid arthritis, systemic lupus erythematosus	BLK COG6	4.93e-04	10	99	2	EFO_0000685, MONDO_0007915
Disease	growth-regulated alpha protein measurement	OR10J3 OR10J1 OR10J5	8.47e-04	55	99	3	EFO_0008146
Disease	Amino Acid Metabolism, Inherited Disorders	GAMT ALDH6A1	8.48e-04	13	99	2	C0750905
Disease	Amino Acid Metabolism, Inborn Errors	GAMT ALDH6A1	8.48e-04	13	99	2	C0002514
Disease	Autistic Disorder	ACADSB NBEA SEZ6L2 TRRAP PASK	1.90e-03	261	99	5	C0004352

Protein segments in the cluster

Peptide	Gene	Start	Entry
VAGFLLPLLVMAYCY	CXCR3	221	P49682
MINISIGYRYPICLG	ERVK-9	151	Q9UKH3
QAEYCIARMAPYTGP	ACTN1	856	P12814
YEPDYRDNCGVTALM	ANKRD16	196	Q6P6B7
NGGTLYTCALRPMYI	HSD3B1	176	P14060
CYIYNKPGDDIVLMA	BRD4	136	O60885
DFGPLNLAMVYRYCC	CDC14A	51	Q9UNH5
AYCALENLYLLMGRE	EFL1	556	Q7Z2Z2
ARMASLLLENPYYGC	ABHD18	136	Q0P651
AEYCIARMAPYQGPD	ACTN4	876	O43707
MLGLAQGCFDYTIPY	ACADSB	301	P45954
MGILYSEPICQAAYQ	ANKRD22	1	Q5VYY1
GESPIYMYLQRSCNV	ANKRD61	311	A6NGH8
VGCYMVIYLGRTPEA	CDC14C	106	A4D256
VIRYCTMYNNGGIPL	ATP2C2	516	O75185
CQMEVLDRYCSIPGY	ADAMTS14	1071	Q8WXS8
RDGYYIQAQCAIIMF	RAN	76	P62826
QAYLAACRMYPKVPV	OTUD4	726	Q01804
LYSYGMLLPCGVDQF	APLP2	181	Q06481
GSMAYNRYIAICNPL	OR8I2	116	Q8N0Y5
DRYVAICNPLLYMVV	OR8U8	121	P0C7N1
DMDLYSYRLPLGVCA	ALDH6A1	166	Q02252
CLMAGGYEVIYLTEP	HSP90B2P	196	Q58FF3
GLMAYDRYVAICNPL	OR2T1	166	O43869
LGLMAYDRYVAVCNP	OR2T2	116	Q6IF00
IEYCAPEVLMGNPYR	PASK	1166	Q96RG2
YSGVNRPRNIMVYNC	FAR1	291	Q8WVX9
LGLPQYRSYFMECLV	PPFIA4	956	O75335
VNMQIRPYVGCLVQY	IPO11	591	Q9UI26
RPRNIYGMVCYSCLL	EDAR	126	Q9UNE0
PYCSGLGYIMSRDLV	B3GALNT1	236	O75752
GSVAPDLYCMCGRIY	MAP3K6	346	O95382
RYPVAVAAAGDLMYL	FBXW8	356	Q8N3Y1
GLMAYDRYVAICNPL	OR2T6	116	Q8NHC8
AIVFMYRCDPAQGQL	PEAK1	986	Q9H792
IDYCGYSVLPMAVEQ	GALK2	51	Q01415
CRPQLAEQYYDMLIE	NIPBL	1841	Q6KC79
GLPQYRSYFMECLVD	PPFIA1	976	Q13136
GYRMVRPDNCPEELY	LCK	456	P06239
PEAAAMDYVGGYALC	FAHD1	86	Q6P587
CGLTIDYPNRLLYFM	LRP2	1601	P98164
GLMSYDRYVAICNPL	OR2T27	116	Q8NH04
GVMAFDRYVAICNPL	OR13C5	116	Q8NGS8
GLMAYDRYVAVCNPL	OR2T35	116	Q8NGX2
DRYVAICNPLLYMVV	OR8J3	121	Q8NGG0
VCFMLILYQYAGPGL	HS6ST1	26	O60243
QLLQMYYEGRFPCLE	NAT10	646	Q9H0A0
IPNFSYMGARLCNYL	PAIP1	211	Q9H074
VNRMYAICRSYPGLL	SBF1	1156	O95248
AAMGFDRYVAICAPL	OR10Z1	116	Q8NGY1
DYLPERQKYEMLCRG	P4HA1	281	P13674
TLVCYGLMARRLYQP	P2RY4	216	P51582
DRYVAICNPLLYMVV	OR8J1	121	Q8NGP2
AVMAYDRYLAICGPL	OR6P1	116	Q8NGX9
CRAYGEVYAAVMNPI	COG6	621	Q9Y2V7
EGLPMLNARYYHCAV	KLHL23	351	Q8NBE8
LLVMGRGYNYATCLE	GFPT2	541	O94808
RVTVPGNYYQLMCGL	FCGBP	2576	Q9Y6R7
EPIYIVTEYMARGCL	BLK	306	P51451
TLLCVEGAAMLYYPS	GPR143	166	P51810
PDYAMIAEIVLYSCG	DNAH7	1456	Q8WXX0
MLGYLSALCQACAYP	FAM120C	146	Q9NX05
EHPNYVDCYLRLGAM	CTR9	526	Q6PD62
FGYCPRVYCENQPML	CSNK2B	106	P67870
LFMAVYKVCYEGQPV	GPD1	321	P21695
VMALVPPADCRYYAF	GAMT	211	Q14353
YRVLMQLCSHYGQPV	DENND4B	816	O75064
LCALYAPICMEYGRV	FZD3	81	Q9NPG1
SRAVGYVMCSLLYPL	SLC44A2	351	Q8IWA5
DDLCLVYVYMPNGSL	IRAK4	256	Q9NWZ3
VMCEDRNLPYVYIPS	NHP2	96	Q9NX24
NYLEIEGMANCLPFY	PMS1	831	P54277
LTAMGYDRYVAICNP	OR10J1	126	P30954
GLMAYDRYAAICRPL	OR5F1	116	O95221
AGARVFEYMALNPCI	ABCB8	441	Q9NUT2
LTVMGYDRYVAICNP	OR10J3	116	Q5JRS4
TAMGYDRYVAICRPL	OR10J5	116	Q8NHC4
AVMGYDRYIAICNPL	OR10K2	116	Q6IF99
GVMGYDRYAAICHPL	OR10R2	136	Q8NGX6
GTMALDRYVAICYPL	OR13C8	116	Q8NGS7
DRYVAICNPLLYMVV	OR8U1	121	Q8NH10
RAICEYNENPKGYML	RPGR	911	Q92834
RMYTIPLYEDLCTGA	RNPEPL1	631	Q9HAU8
MALAVRVVYCGAUGY	SELENOW	1	P63302
RELGYLNKMDLPYRC	TIFA	101	Q96CG3
DGISYLLQMLNYRCP	RIMOC1	166	A6NDU8
QLYIYPGCDAGIRAM	NBEA	2896	Q8NFP9
ARVVGGYLLMLAYAC	PTCH2	396	Q9Y6C5
GELYGYACMIRVNPF	SLFN11	306	Q7Z7L1
GIIPYACTDLAVYEM	SLC25A41	251	Q8N5S1
YRCLPGYSLEGAAML	SEZ6L2	731	Q6UXD5
ASAMLLRDVPGYCLY	SLC25A48	181	Q6ZT89
FYICLLMYIGPSEEG	OR5K4	251	A6NMS3
CVPYLGMYLTDLAFI	RASGRF1	1186	Q13972
YICEMALALDYLRGQ	STK32C	196	Q86UX6
EEFCYQPMAVLGYER	CHST2	496	Q9Y4C5
IRNAPDLNNMYCGYI	CLEC12A	216	Q5QGZ9
YCYQGGRVICRVIMP	TNMD	291	Q9H2S6
DEGIYNCYIMNPPDR	SCN2B	121	O60939
LIGIYPEYDDCMFSR	SMC1B	1196	Q8NDV3
IRCLGYVIDNYFPEM	PLEKHG4B	821	Q96PX9
YMLCRNLPYGFIQEL	UBE4B	491	O95155
YVPQLYDCMQDLGVI	TBC1D9	656	Q6ZT07
LMCCGRGYNPYTDRV	WNT11	311	O96014
GAGHLICLYCYQMPL	PIEZO1	256	Q92508
LPLGYYVGMCLAASE	TMEM129	66	A0AVI4
HEVLNPMYCLFEYAG	WWP1	621	Q9H0M0
MYRGYLAICHPEEQQ	TRRAP	2886	Q9Y4A5
YLGNVFPAEMDYLRC	MLC1	71	Q15049
VFGRMYELSCYLPQE	MYOF	1601	Q9NZM1
MESCYNPGLDGIIEY	NFKB2	1	Q00653