Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEGF_CA

FBN2 TLL1

6.83e-0386272PF07645
Pubmed

Fatty acids and inflammatory stimuli induce expression of long-chain acyl-CoA synthetase 1 to promote lipid remodeling in diabetic kidney disease.

ACSL1 LEPR

6.71e-07229238016515
Pubmed

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

LRRK2 PITX3

2.01e-06329226123485
Pubmed

Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.

LEPR LRRK2

2.01e-06329222357653
Pubmed

Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.

NFATC1 LRRK2

4.02e-06429237300531
Pubmed

Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.

ACSL1 LEPR

1.00e-05629219834009
Pubmed

Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.

KBTBD2 LEPR

2.41e-05929227708159
Pubmed

MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.

MESP2 FBN2

2.41e-05929225652402
Pubmed

Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.

SETD4 HSD3B1

3.28e-043229222737085
Pubmed

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.

HSD3B1 LEPR

3.28e-043229234288113
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

CGNL1 NFATC1 LEPR

3.38e-0416329335364055
Pubmed

Tracing the origin of hair follicle stem cells.

FBN2 NFATC1

3.93e-043529234108685
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRZ1 LEPR

7.09e-044729219167335
Pubmed

Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition.

ACSL1 NFATC1

7.09e-044729217198697
Cytoband7p14.3

KBTBD2 ITPRID1

2.67e-04382927p14.3
CytobandEnsembl 112 genes in cytogenetic band chr7p14

KBTBD2 ITPRID1

5.42e-03174292chr7p14
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN

NKTR BBX CD6 CNOT2 ARID5A ZC3H12D

4.27e-06432276M41149
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

DNAH2 ACSL1 FBN2 NFATC1 PTPRZ1 LEPR TLL1 LRRK2

3.37e-051148258facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 LEPR ARID5A LRRK2

4.51e-06185274fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 LEPR ARID5A LRRK2

4.71e-06187274ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 LEPR ARID5A LRRK2

4.71e-0618727437d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR TLL1

4.91e-0618927475c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR TLL1

4.91e-06189274c81787a8c662db5d7814c583dd64562857629e81
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

CGNL1 SHROOM2 LEPR TLL1

5.22e-06192274c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR TLL1

5.33e-0619327401c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR TLL1

5.33e-061932742531266bc57339d4e2b22a88817008e32b8c1598
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 LEPR ARID5A LRRK2

6.02e-061992740075bcc7d2a5031e76a24cb176e16ac998d846fd
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CD6 ITPRID1 ZC3H12D

6.45e-0660273831efcadd99ad04d37cd763ecf8aaa439b09046d
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CD6 ITPRID1 ZC3H12D

6.45e-0660273604f050cafb1c2378a6957831833d47ff555c1fd
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CD6 PTPRZ1 ZC3H12D

7.49e-051362735e209185b5f6e9347829fc9066f0b2c3711df057
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CGNL1 ARID5A ZC3H12D

8.34e-05141273f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CGNL1 ARID5A ZC3H12D

8.34e-05141273bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCellTCGA-Uterus|World / Sample_Type by Project: Shred V9

MAMSTR FBN2 PITX3

8.88e-051442737efb45286ebf2dbfb9125fd6373f28dccb029a2e
ToppCellmetastatic_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

BBX LEPR ARID5A

9.82e-0514927304c696f5102b0fff7d80e0f8d12a3119b2b81898
ToppCellmild-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACSL1 SHROOM2 DMTN

1.00e-04150273979566663d1110475f1e017c2f9890aca4b6f701
ToppCellP03-Epithelial-epithelial_progenitor_cell-epi_progenitor|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIAA1755 MESP2 LRRK2

1.02e-04151273fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 PTPRZ1 TLL1

1.21e-04160273c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 PTPRZ1 TLL1

1.21e-0416027325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 CGNL1 ITPRID1

1.24e-0416127341a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 CGNL1 ITPRID1

1.24e-04161273c4970501c038ed36de447da70eabff020ad78713
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 ITPRID1 SHROOM2

1.26e-04162273ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCellT_cells-Tph_and_Tfh|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD6 ARID5A ZC3H12D

1.26e-04162273146058f2d60846376078916055d08f68562e3a7c
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CD6 NFATC1 ZC3H12D

1.30e-04164273b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CGNL1 ITPRID1 SHROOM2

1.43e-0416927305e12524d68d409fed386ffad233305683b4575b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 SHROOM2 LRRK2

1.61e-0417627333323c97afe509147956b8df9f92ca6b0537e604
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITPRID1 PTPRZ1 TLL1

1.63e-04177273a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFATC1 DMTN ZC3H12D

1.63e-04177273d5503605d46a335cc7ca1f94626809f9e1b505e2
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITPRID1 PTPRZ1 TLL1

1.63e-04177273363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 ITPRID1 PTPRZ1

1.66e-04178273fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 ITPRID1 PTPRZ1

1.66e-04178273b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 CGNL1 ITPRID1

1.74e-04181273092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellfacs-GAT-Fat-24m-Lymphocytic|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD6 ARID5A ZC3H12D

1.80e-04183273377c2c6fcb2fd41396dd7a7a90e9d7ccafccf2f0
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

1.80e-04183273764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MESP2 CGNL1 SHROOM2

1.80e-041832736c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

ITPRID1 PTPRZ1 TLL1

1.80e-04183273940cbe298e9c53b5622af09264586ed823d3141f
ToppCellfacs-GAT-Fat-24m-Lymphocytic-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD6 ARID5A ZC3H12D

1.80e-04183273f0a6f4f8563491c83fb991b9fb81e75fec7d1ace
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFATC1 ARID5A TLL1

1.83e-0418427316ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

1.83e-041842733b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NKTR CD6 ZC3H12D

1.83e-04184273bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NFATC1 TLL1 DMTN

1.86e-04185273f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

1.89e-041862739579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CGNL1 LEPR DMTN

1.92e-041872737e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR

1.92e-041872737876dcb4800c2e54874df3d933efb79307a64a97
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACSL1 KIAA1755 LRRK2

1.92e-041872733b1439018e265a61d9599e307a202e3c2f60ed32
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

LEPR ARID5A TLL1

1.92e-0418727381affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACSL1 KIAA1755 LRRK2

1.92e-04187273e99bc27d212c74da37770297122a4b30445ccd0d
ToppCell390C-Lymphocytic-CD4_T-cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CD6 ARID5A ZC3H12D

1.95e-041882730da6d6d3c28e9d99159b1a24a345a2250e8e1995
ToppCellfacs-MAT-Fat-18m-Lymphocytic|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD6 ARID5A ZC3H12D

1.95e-04188273613d4484d8d00ed18e5061bd0957b6beef6be8dd
ToppCellfacs-MAT-Fat-18m-Lymphocytic-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD6 ARID5A ZC3H12D

1.95e-041882736cd04603bf5ca4d23a31ebced7535999583e1265
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACSL1 KIAA1755 LRRK2

1.95e-04188273fbf176b48b89c234e4e1e64739afc836bed78a96
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD6 NFATC1 ARID5A

1.95e-04188273939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NFATC1 TLL1 DMTN

1.98e-0418927355a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CGNL1 LEPR TLL1

1.98e-041892737346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 LEPR TLL1

1.98e-041892730739baad9a7da511dd3d7249f84299aee88370a1
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

2.01e-04190273b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LEPR ARID5A TLL1

2.01e-0419027307b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 CGNL1 LRRK2

2.01e-0419027359bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIAA1755 FBN2 LEPR

2.04e-0419127375d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIAA1755 FBN2 LEPR

2.04e-041912734b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACSL1 FBN2 LRRK2

2.04e-0419127347a2afc4102199b4bc76bd01b2967c8016186462
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD6 NFATC1 ARID5A

2.08e-041922733e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CGNL1 SHROOM2 TLL1

2.08e-0419227314a816ef116aa992f86edab411f043cf7d07fe04
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CD6 ARID5A ZC3H12D

2.08e-04192273494c5eca0f07fc761f26487a2b937c7056bbe594
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

NKTR CD6 ZC3H12D

2.08e-0419227347646d7e4990be85072987f92bf18d52f8da752e
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CGNL1 SHROOM2 TLL1

2.08e-04192273847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

2.08e-041922735388f3115ab285f3f3001af1d71543ed64b9e044
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFATC1 TLL1 DMTN

2.11e-04193273ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CNOT2 ARID5A TLL1

2.11e-04193273479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

ACSL1 FBN2 LRRK2

2.14e-041942739e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

CGNL1 SHROOM2 LEPR

2.14e-04194273b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CGNL1 DMTN PITX3

2.14e-041942739441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKTR LEPR TLL1

2.17e-0419527381a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCelldistal-Hematologic-Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACSL1 FBN2 LRRK2

2.17e-0419527332c34741e35006b7238896fd04a497011297dd22
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACSL1 FBN2 LRRK2

2.17e-04195273580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCellT_cells-CCR7+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD6 ARID5A ZC3H12D

2.24e-04197273904430779c42b51d3eec62cf0cdd501b17058d8b
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACSL1 FBN2 LRRK2

2.24e-04197273b91016249b3585aa3536e96af18e4f1b1d2d5ce4
ToppCelldistal-2-Hematologic-Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACSL1 FBN2 LRRK2

2.24e-041972739a1c9221904ad1e46e64e3785516804e87128adc
ToppCellEpithelial_cells-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ACSL1 ESD LRRK2

2.24e-0419727359aa28a377315dfcda4d9b6ecd3419157654f24e
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACSL1 FBN2 LRRK2

2.24e-04197273ec46aa307ce5774b4c0fcba64514f2d0cab3c4f9
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-Activated_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD6 NFATC1 ARID5A

2.24e-041972732f2e5a5e1cb00b9e51c1a9f86d34ac65cb8b3999
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ACSL1 CGNL1 LRRK2

2.27e-0419827385215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH2 MESP2 PTPRZ1

2.27e-041982736712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITPRID1 PTPRZ1 TLL1

2.27e-04198273fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LEPR ARID5A TLL1

2.27e-04198273002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ACSL1 CGNL1 LRRK2

2.27e-0419827338349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACSL1 ARID5A DMTN

2.31e-0419927350242666def13e5d4149c563ae000d6768f086f7
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|Control_saline / Treatment groups by lineage, cell group, cell type

ACSL1 ARID5A LRRK2

2.31e-04199273e1240bfcdce76ec018599c50350748f9c7b8fb0e
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 TLL1 LRRK2

2.34e-042002734fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 TLL1 LRRK2

2.34e-04200273f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 TLL1 LRRK2

2.34e-04200273cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 ITPRID1 PTPRZ1

2.34e-04200273030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellproximal-3-Endothelial-Bronchial_Vessel_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LEPR ARID5A TLL1

2.34e-042002730ff4185021ec84b57be13b28495e2f8a4d195eb6
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 TLL1 LRRK2

2.34e-04200273310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 CGNL1 ITPRID1

2.34e-042002730eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 TLL1 LRRK2

2.34e-04200273c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ACSL1 FBN2 LRRK2

2.34e-042002739e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 ITPRID1 PTPRZ1

2.34e-042002737c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellproximal-Endothelial-Bronchial_Vessel_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LEPR ARID5A TLL1

2.34e-04200273e4f6e0b9502eb531f28d605f9dbda6a72a9ed320
Diseasequinate measurement

LEPR LRRK2

7.78e-0515262EFO_0021167
Diseasecerebrospinal fluid biomarker measurement

KIAA1755 LEPR ESD

8.22e-0596263EFO_0006794
Diseasecalcium measurement

DNAH2 FBN2 CGNL1 BBX DMTN

1.95e-04628265EFO_0004838
Diseasecongenital heart disease (is_implicated_in)

NFATC1 TLL1

2.04e-0424262DOID:1682 (is_implicated_in)
Diseaseatrial fibrillation

KIAA1755 CGNL1 NFATC1 PITX3

2.95e-04371264EFO_0000275
Diseasesex interaction measurement, Crohn's disease

MAMSTR LRRK2

4.88e-0437262EFO_0000384, EFO_0008343
DiseaseCrohn's disease

MAMSTR CD6 NFATC1 LRRK2

5.67e-04441264EFO_0000384
Diseasetestosterone measurement

DNAH2 FBN2 BBX NFATC1 LEPR TLL1

7.03e-041275266EFO_0004908
Diseasetype 1 diabetes mellitus

DNAH2 ACSL1 CD6

1.23e-03242263MONDO_0005147
Diseasecomplex trait

MAMSTR KIAA1755 LEPR

1.70e-03271263EFO_0010578
Diseasemean platelet volume

ACSL1 BBX NFATC1 LEPR LRRK2

1.76e-031020265EFO_0004584
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

CD6 NFATC1 LRRK2

2.17e-03295263EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
DiseaseColorectal Carcinoma

SETD4 FBN2 ITPRID1 NFATC1

3.13e-03702264C0009402
Diseasecoronary artery disease (is_implicated_in)

LEPR TLL1

3.50e-03100262DOID:3393 (is_implicated_in)
DiseaseAlloxan Diabetes

ACSL1 LEPR

4.07e-03108262C0002152
DiseaseStreptozotocin Diabetes

ACSL1 LEPR

4.07e-03108262C0038433
DiseaseDiabetes Mellitus, Experimental

ACSL1 LEPR

4.07e-03108262C0011853

Protein segments in the cluster

PeptideGeneStartEntry
LPPKAETGKCPALYW

ESD

36

P10768
KGILYPKPKACWVSP

ARID5A

406

Q03989
GYKWCPTTNKPVKSP

BBX

146

Q8WY36
PLENTWPAPYPHSKK

HSD3B1

146

P14060
TFWYATRPKPLKPPC

ACSL1

41

P33121
DYCNSPKSKLPPWNP

CD6

571

P30203
PYPPHGLLSKQWPCS

ITPRID1

326

Q6ZRS4
PWKVLCSLYSPKPNR

KIAA1755

496

Q5JYT7
WATPPYCPKIQSPPY

MESP2

246

Q0VG99
QHPYQWAKPKPLSPT

NFATC1

391

O95644
LYPSCLEESPWKPPT

KBTBD2

586

Q8IY47
KLPDPVKEYGCAPWP

LRRK2

2091

Q5S007
YPITPWRFKLSCMPP

LEPR

26

P48357
PPQRWCLQVYPTAPK

ERVK-5

11

P61583
FQCPKWPNPDSPISK

PTPRZ1

2186

P23471
KKPWTCFPKPSNSQP

CGNL1

186

Q0VF96
APCWFPPGYPEAKKV

REXO1L1P

6

Q8IX06
LPEPEYCPPWRSPKK

MAMSTR

66

Q6ZN01
YCPPWRSPKKESPKI

MAMSTR

71

Q6ZN01
QLPAKCLPKYPSKWT

LCE7A

11

P0DV60
CLPKYPSKWTPQAPA

LCE7A

16

P0DV60
YNVGKAWNKPCEPCP

FBN2

1766

P35556
PNQPAKIETDYWPCP

DMTN

181

Q08495
DKLPKSWRYPPNAPF

DNAH2

2371

Q9P225
WPPKALAPPLAAKTF

PITX3

156

O75364
TPGWPKEYPPNKNCV

TLL1

631

O43897
PSRWKPGQKPWKPSY

NKTR

616

P30414
YITKWKPPPSPLLAL

SETD4

96

Q9NVD3
VWYVPDKKKAPSSPP

SHROOM2

301

Q13796
YPKFASPWASSPCRP

CNOT2

396

Q9NZN8
KPPEPSWQHCPYGKK

ZC3H12D

251

A2A288