Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.27e-06	5	139	3	GO:0030156
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM AGL MGAM2	1.13e-05	7	139	3	GO:0090599
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	1.66e-05	46	139	5	GO:0030020
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	4.81e-05	2	139	2	GO:0004339
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A3 COL13A1 COL19A1 VWA1 COL24A1 MUC5AC TNXB COL1A2	5.24e-05	188	139	8	GO:0005201
GeneOntologyMolecularFunction	semaphorin receptor activity	NRP1 PLXNB1 PLXNB3	6.94e-05	12	139	3	GO:0017154
GeneOntologyMolecularFunction	glucosidase activity	MGAM AGL MGAM2	1.41e-04	15	139	3	GO:0015926
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	4.75e-04	5	139	2	GO:0004558
GeneOntologyMolecularFunction	microfibril binding	POLR2A VWA1	7.09e-04	6	139	2	GO:0050436
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A10	7.09e-04	6	139	2	GO:0008510
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MGAM TREH AGL FUCA1 MGAM2	7.71e-04	103	139	5	GO:0004553
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	SIRPB1 SIRPG CNTN2 PLXNB3	8.63e-04	61	139	4	GO:0098632
GeneOntologyBiologicalProcess	neuron development	TRIM46 EPHB6 SEMA6C RPGRIP1 SLC4A7 PLK5 ETV4 BDNF TIAM2 BTBD3 NRP1 ABLIM1 ARID1B DST TRIM32 PTPRS CSPG4 IQSEC1 SLC4A10 NHLH2 COBL HERC1 TNXB VPS13B CNTN2 PLXNB1 PLXNB3	1.42e-06	1463	139	27	GO:0048666
GeneOntologyBiologicalProcess	regulation of axonogenesis	TRIM46 SEMA6C BDNF TIAM2 NRP1 PTPRS CNTN2 PLXNB1 PLXNB3	6.30e-06	192	139	9	GO:0050770
GeneOntologyBiologicalProcess	neuron projection development	TRIM46 EPHB6 SEMA6C PLK5 ETV4 BDNF TIAM2 BTBD3 NRP1 ABLIM1 ARID1B DST TRIM32 PTPRS CSPG4 IQSEC1 COBL HERC1 TNXB VPS13B CNTN2 PLXNB1 PLXNB3	1.59e-05	1285	139	23	GO:0031175
GeneOntologyBiologicalProcess	axon development	TRIM46 EPHB6 SEMA6C ETV4 BDNF TIAM2 NRP1 ABLIM1 DST TRIM32 PTPRS COBL CNTN2 PLXNB1 PLXNB3	2.93e-05	642	139	15	GO:0061564
GeneOntologyBiologicalProcess	axonogenesis	TRIM46 EPHB6 SEMA6C ETV4 BDNF TIAM2 NRP1 ABLIM1 DST PTPRS COBL CNTN2 PLXNB1 PLXNB3	2.95e-05	566	139	14	GO:0007409
GeneOntologyBiologicalProcess	retina vasculature morphogenesis in camera-type eye	SLC4A7 NRP1 LRP5	4.75e-05	11	139	3	GO:0061299
GeneOntologyBiologicalProcess	extracellular matrix organization	COL4A3 FKBP10 COL13A1 COL19A1 TMPRSS6 VWA1 ITIH1 ADAMTS10 COL24A1 TNXB COL1A2	5.09e-05	377	139	11	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL4A3 FKBP10 COL13A1 COL19A1 TMPRSS6 VWA1 ITIH1 ADAMTS10 COL24A1 TNXB COL1A2	5.21e-05	378	139	11	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL4A3 FKBP10 COL13A1 COL19A1 TMPRSS6 VWA1 ITIH1 ADAMTS10 COL24A1 TNXB COL1A2	5.34e-05	379	139	11	GO:0045229
GeneOntologyBiologicalProcess	negative regulation of axon extension	TRIM46 SEMA6C NRP1 PTPRS	1.22e-04	38	139	4	GO:0030517
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	TRIM46 EPHB6 SEMA6C ETV4 BDNF TIAM2 BTBD3 NRP1 ABLIM1 DST PTPRS COBL CNTN2 PLXNB1 PLXNB3	1.62e-04	748	139	15	GO:0048667
GeneOntologyCellularComponent	semaphorin receptor complex	NRP1 PLXNB1 PLXNB3	8.18e-05	13	141	3	GO:0002116
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL4A3 FKBP10 COL13A1 COL19A1 VWA1 PTGS2 BDNF COL24A1 VCPIP1 COL1A2	8.77e-05	332	141	10	GO:0005788
GeneOntologyCellularComponent	collagen trimer	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	3.25e-04	88	141	5	GO:0005581
Domain	FN3	TRIM46 EPHB6 VWA1 RIMBP3 PTPRS RIMBP3C MERTK RIMBP3B TNXB CNTN2	2.13e-06	199	137	10	PS50853
Domain	FN3_dom	TRIM46 EPHB6 VWA1 RIMBP3 PTPRS RIMBP3C MERTK RIMBP3B TNXB CNTN2	3.31e-06	209	137	10	IPR003961
Domain	FN3	TRIM46 EPHB6 VWA1 PTPRS RIMBP3C MERTK RIMBP3B TNXB CNTN2	9.11e-06	185	137	9	SM00060
Domain	-	IGSF8 TRIM46 EPHB6 SIRPB1 VWA1 SIRPG RIMBP3 PTPRS SIGIRR RIMBP3C MERTK RIMBP3B TNXB CNTN2 PLXNB1 PLXNB3	2.91e-05	663	137	16	2.60.40.10
Domain	Ig-like_fold	IGSF8 TRIM46 EPHB6 SIRPB1 VWA1 SIRPG RIMBP3 PTPRS SIGIRR RIMBP3C MERTK RIMBP3B TNXB CNTN2 PLXNB1 PLXNB3	6.16e-05	706	137	16	IPR013783
Domain	-	RASA4 RASA4B	1.59e-04	3	137	2	4.10.1130.10
Domain	fn3	TRIM46 EPHB6 VWA1 PTPRS MERTK TNXB CNTN2	1.94e-04	162	137	7	PF00041
Domain	RasGAP_dom	RASA4 RASA4B PLXNB1	2.91e-04	18	137	3	IPR001936
Domain	Gal_mutarotase_N	MGAM MGAM2	3.17e-04	4	137	2	IPR031727
Domain	NtCtMGAM_N	MGAM MGAM2	3.17e-04	4	137	2	PF16863
Domain	Collagen	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	4.04e-04	85	137	5	IPR008160
Domain	Collagen	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	4.04e-04	85	137	5	PF01391
Domain	Anion_exchange	SLC4A7 SLC4A10	5.26e-04	5	137	2	IPR001717
Domain	Glycoside_hydrolase_SF	MGAM AGL FUCA1 MGAM2	6.14e-04	53	137	4	IPR017853
Domain	Glyco_hydro_31_AS	MGAM MGAM2	7.86e-04	6	137	2	IPR030458
Domain	-	TXNRD1 AIFM3	1.09e-03	7	137	2	3.30.390.30
Domain	Glyco_hydro_31	MGAM MGAM2	1.09e-03	7	137	2	IPR000322
Domain	Glyco_hydro_31	MGAM MGAM2	1.09e-03	7	137	2	PF01055
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A10	1.09e-03	7	137	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A10	1.09e-03	7	137	2	PS00219
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	1.09e-03	7	137	2	PS00129
Domain	ConA-like_dom	TRIM46 COL19A1 DDX1 NRP1 COL24A1 CSPG4 HERC1	1.18e-03	219	137	7	IPR013320
Domain	Pyr_nucl-diS_OxRdtase_dimer	TXNRD1 AIFM3	1.45e-03	8	137	2	IPR004099
Domain	FAD/NAD-linked_Rdtase_dimer	TXNRD1 AIFM3	1.45e-03	8	137	2	IPR016156
Domain	Trefoil	MGAM MGAM2	1.45e-03	8	137	2	PF00088
Domain	Semap_dom	SEMA6C PLXNB1 PLXNB3	1.49e-03	31	137	3	IPR001627
Domain	SEMA	SEMA6C PLXNB1 PLXNB3	1.49e-03	31	137	3	PS51004
Domain	Sema	SEMA6C PLXNB1 PLXNB3	1.49e-03	31	137	3	SM00630
Domain	Sema	SEMA6C PLXNB1 PLXNB3	1.49e-03	31	137	3	PF01403
Domain	Plexin_repeat	SEMA6C PLXNB1 PLXNB3	1.64e-03	32	137	3	IPR002165
Domain	PSI	SEMA6C PLXNB1 PLXNB3	1.64e-03	32	137	3	PF01437
Domain	BTK	RASA4 RASA4B	1.86e-03	9	137	2	SM00107
Domain	Plexin_cytopl	PLXNB1 PLXNB3	1.86e-03	9	137	2	PF08337
Domain	-	SLC4A7 SLC4A10	1.86e-03	9	137	2	3.40.1100.10
Domain	P_TREFOIL_2	MGAM MGAM2	1.86e-03	9	137	2	PS51448
Domain	Znf_Btk_motif	RASA4 RASA4B	1.86e-03	9	137	2	IPR001562
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNB1 PLXNB3	1.86e-03	9	137	2	IPR013548
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A10	1.86e-03	9	137	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A10	1.86e-03	9	137	2	PF07565
Domain	Plexin	PLXNB1 PLXNB3	1.86e-03	9	137	2	IPR031148
Domain	BTK	RASA4 RASA4B	1.86e-03	9	137	2	PF00779
Domain	ZF_BTK	RASA4 RASA4B	1.86e-03	9	137	2	PS51113
Domain	PD	MGAM MGAM2	1.86e-03	9	137	2	SM00018
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	2.56e-05	44	113	5	M27812
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A3 COL13A1 COL19A1 TMPRSS6 COL1A2	6.39e-05	53	113	5	MM14566
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A3 COL13A1 COL19A1 COL24A1 DST COL1A2	8.36e-05	90	113	6	M631
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A3 COL13A1 COL19A1 TMPRSS6 COL1A2	1.58e-04	64	113	5	M26953
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	1.97e-04	67	113	5	M26999
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL4A3 COL13A1 COL19A1 VWA1 MED1 BDNF CSPG4 TNXB COL1A2	2.24e-07	210	142	9	16537572
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL4A3 COL13A1 COL19A1 VWA1 ITIH1 COL24A1 TNXB COL1A2	2.38e-07	153	142	8	25037231
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.66e-07	4	142	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	6.62e-07	5	142	3	17855024
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	SIRPB1 F11 NRP1 PTPRS CSPG4 MERTK TNXB CNTN2 PLXNB1	1.21e-06	257	142	9	16335952
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A3 COL13A1 ITIH1 COL24A1 CSPG4 TNXB COL1A2	1.46e-06	135	142	7	28675934
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ARPP19 SLC4A7 TEX2 POLR2A KIAA1191 GPKOW GATAD2B ABLIM1 ARID1B SCAP TNRC6A XRN1 MGA VCPIP1	2.02e-06	733	142	14	34672954
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA6C NRP1 CNTN2 PLXNB1 PLXNB3	2.35e-06	52	142	5	26633812
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C POLR2A C15orf39 SLC1A5 TIAM2 FZD7 SCAP DST PTPRS KLHL21 RRP12 CSPG4 LRP5 COBL HERC1 PRDM16 MED13	2.93e-06	1105	142	17	35748872
Pubmed	Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.	SIRPB1 SIRPG GAB4	5.50e-06	9	142	3	11895767
Pubmed	Functional proteomics mapping of a human signaling pathway.	EGLN2 TCTA GATAD2B ARID1B DST CSPG4 LRP5 FTL HERC1 MERTK MGA VCPIP1	6.09e-06	591	142	12	15231748
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	EPHB6 SEMA6C NRP1 FZD7 PLXNB1 PLXNB3	8.98e-06	117	142	6	17145500
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	NRP1 PLXNB1 PLXNB3	1.43e-05	12	142	3	21270798
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ABCF1 PPFIBP1 C15orf39 SRPK2 DDX1 NRP1 DST MGST3 TRIM32 XRN1 STARD3 PLXNB1	1.57e-05	650	142	12	38777146
Pubmed	Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor.	BDNF PTPRS	1.66e-05	2	142	2	15842738
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	1.66e-05	2	142	2	11448776
Pubmed	SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.	ENTPD7 ARID1B	1.66e-05	2	142	2	27737960
Pubmed	Developmental regulation of notochord-derived repulsion for dorsal root ganglion axons.	NRP1 CNTN2	1.66e-05	2	142	2	15019939
Pubmed	PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.	MED1 PRDM16	1.66e-05	2	142	2	25644604
Pubmed	CFAP61 knockdown aggravates male infertility by inhibiting testosterone secretion by Leydig cells via the MAPK/COX-2 pathway.	PTGS2 CFAP61	1.66e-05	2	142	2	37982895
Pubmed	Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus.	TNXA TNXB	1.66e-05	2	142	2	1373808
Pubmed	Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.	TNXA TNXB	1.66e-05	2	142	2	8530023
Pubmed	Bone mineral properties in growing Col1a2(+/G610C) mice, an animal model of osteogenesis imperfecta.	LRP5 COL1A2	1.66e-05	2	142	2	27083399
Pubmed	Cord Blood-Derived Exosomal CNTN2 and BDNF: Potential Molecular Markers for Brain Health of Neonates at Risk for Iron Deficiency.	BDNF CNTN2	1.66e-05	2	142	2	31623079
Pubmed	Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.	SLC4A7 SLC4A10	1.66e-05	2	142	2	17928512
Pubmed	Combination therapy in the Col1a2G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone.	LRP5 COL1A2	1.66e-05	2	142	2	31648079
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	1.66e-05	2	142	2	16041389
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	NRP1 PLXNB1 PLXNB3	1.85e-05	13	142	3	10520995
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	2.35e-05	14	142	3	17662146
Pubmed	A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.	POLR2A MED1 MED13	2.35e-05	14	142	3	10024883
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TEX2 PPFIBP1 KIAA1191 DST TNRC6A COBL VCPIP1	2.56e-05	209	142	7	36779422
Pubmed	Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.	TRIM46 TRIM32 VCPIP1	2.92e-05	15	142	3	29295817
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	IGSF8 ENTPD7 FKBP10 ABCF1 CPD BDNF DDX1 NRP1 SCAP MGST3 PTPRS RRP12 CSPG4 LRP5 POFUT2 PLXNB1	3.40e-05	1201	142	16	35696571
Pubmed	The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.	TMPRSS6 FBXL5 FTL	3.59e-05	16	142	3	21907140
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	IGSF8 C15orf39 SLC1A5 NRP1 FZD7 MGST3 FAM222B TNRC6A	4.06e-05	307	142	8	37499664
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	NRP1 PLXNB1 PLXNB3	4.35e-05	17	142	3	17626059
Pubmed	SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis.	SIRPB1 SIRPG	4.95e-05	3	142	2	36202053
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes.	SIRPB1 SIRPG	4.95e-05	3	142	2	15034021
Pubmed	An unequal crossover between the RCCX modules of the human MHC leading to the presence of a CYP21B gene and a tenascin TNXB/TNXA-RP2 recombinant between C4A and C4B genes in a patient with juvenile rheumatoid arthritis.	TNXA TNXB	4.95e-05	3	142	2	10343159
Pubmed	Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice.	PTGS2 PTPRS	4.95e-05	3	142	2	16373427
Pubmed	Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha.	SIRPB1 SIRPG	4.95e-05	3	142	2	34917090
Pubmed	Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.	SIRPB1 SIRPG	4.95e-05	3	142	2	19667119
Pubmed	SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors.	SIRPB1 SIRPG	4.95e-05	3	142	2	28669759
Pubmed	Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.	TNXA TNXB	4.95e-05	3	142	2	2475872
Pubmed	Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virus.	SIRPB1 SIRPG	4.95e-05	3	142	2	12134038
Pubmed	Partial characterization of murine intestinal maltase-glucoamylase.	MGAM TREH	4.95e-05	3	142	2	12150962
Pubmed	Central nervous system antigen P84 can serve as a substrate for neurite outgrowth.	SIRPB1 SIRPG	4.95e-05	3	142	2	2303162
Pubmed	SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.	SIRPB1 SIRPG	4.95e-05	3	142	2	16141346
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	4.95e-05	3	142	2	25637021
Pubmed	A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9.	SIRPB1 SIRPG	4.95e-05	3	142	2	17825046
Pubmed	SIRPα deficiency accelerates the pathologic process in models of Parkinson disease.	SIRPB1 SIRPG	4.95e-05	3	142	2	31322787
Pubmed	The Rho kinase pathway regulates the migration of dendritic cells through SIRP-α.	SIRPB1 SIRPG	4.95e-05	3	142	2	22391241
Pubmed	Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.	SIRPB1 SIRPG	4.95e-05	3	142	2	23472187
Pubmed	Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.	SIRPB1 SIRPG	4.95e-05	3	142	2	31370677
Pubmed	A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.	SIRPB1 SIRPG	4.95e-05	3	142	2	30770827
Pubmed	Signal regulatory protein α protects podocytes through promoting autophagic activity.	SIRPB1 SIRPG	4.95e-05	3	142	2	30888336
Pubmed	Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.	SIRPB1 SIRPG	4.95e-05	3	142	2	38758648
Pubmed	Requirement of SIRPα for protective immunity against Leishmania major.	SIRPB1 SIRPG	4.95e-05	3	142	2	20854790
Pubmed	BIT, an immune antigen receptor-like molecule in the brain.	SIRPB1 SIRPG	4.95e-05	3	142	2	9271230
Pubmed	Gene structure of mouse BIT/SHPS-1.	SIRPB1 SIRPG	4.95e-05	3	142	2	10585853
Pubmed	Etv5, an ETS transcription factor, is expressed in granulosa and cumulus cells and serves as a transcriptional regulator of the cyclooxygenase-2.	ETV4 PTGS2	4.95e-05	3	142	2	18492810
Pubmed	Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.	SIRPB1 SIRPG	4.95e-05	3	142	2	18635660
Pubmed	Mediator and post-recruitment regulation of RNA polymerase II.	POLR2A MED1	4.95e-05	3	142	2	21326907
Pubmed	Resistance to collagen-induced arthritis in SHPS-1 mutant mice.	SIRPB1 SIRPG	4.95e-05	3	142	2	18455510
Pubmed	Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function.	SIRPB1 SIRPG	4.95e-05	3	142	2	19223164
Pubmed	Mutational analysis uncovers monogenic bone disorders in women with pregnancy-associated osteoporosis: three novel mutations in LRP5, COL1A1, and COL1A2.	LRP5 COL1A2	4.95e-05	3	142	2	29594386
Pubmed	Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells.	SIRPB1 SIRPG	4.95e-05	3	142	2	35511221
Pubmed	Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis.	ETV4 PTGS2	4.95e-05	3	142	2	15695237
Pubmed	Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice.	SIRPB1 SIRPG	4.95e-05	3	142	2	12742627
Pubmed	Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.	SIRPB1 SIRPG	4.95e-05	3	142	2	25818708
Pubmed	Chondroitin sulfate acts in concert with semaphorin 3A to guide tangential migration of cortical interneurons in the ventral telencephalon.	NRP1 CSPG4	4.95e-05	3	142	2	20071458
Pubmed	PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1.	MED1 PRDM16	4.95e-05	3	142	2	25644605
Pubmed	Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.	SIRPB1 SIRPG	4.95e-05	3	142	2	26222253
Pubmed	E1A-F is overexpressed early in human colorectal neoplasia and associated with cyclooxygenase-2 and matrix metalloproteinase-7.	ETV4 PTGS2	4.95e-05	3	142	2	15800927
Pubmed	Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.	SIRPB1 SIRPG	4.95e-05	3	142	2	12167615
Pubmed	Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk.	SIRPB1 SIRPG	4.95e-05	3	142	2	31507080
Pubmed	Involvement of signal regulatory protein α, a negative regulator of Toll-like receptor signaling, in impairing the MyD88-independent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages.	SIRPB1 SIRPG	4.95e-05	3	142	2	22988019
Pubmed	Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain.	SIRPB1 SIRPG	4.95e-05	3	142	2	22468987
Pubmed	Effect of Serum Deprivation Stress on Signal Induction Regulatory Protein-Alpha (SIRP-Alpha)-Mediated Erythrophagocytosis by Macrophages.	SIRPB1 SIRPG	4.95e-05	3	142	2	30894504
Pubmed	SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).	SIRPB1 SIRPG	4.95e-05	3	142	2	23022485
Pubmed	Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.	SIRPB1 SIRPG	4.95e-05	3	142	2	29158380
Pubmed	Amyloid β oligomers constrict human capillaries in Alzheimer's disease via signaling to pericytes.	POLR2A CSPG4	4.95e-05	3	142	2	31221773
Pubmed	Lack of non-hematopoietic SIRPα signaling disturbs the splenic marginal zone architecture resulting in accumulation and displacement of marginal zone B cells.	SIRPB1 SIRPG	4.95e-05	3	142	2	25817792
Pubmed	Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.	SIRPB1 SIRPG	4.95e-05	3	142	2	31883525
Pubmed	Signal regulatory protein α is associated with tumor-polarized macrophages phenotype switch and plays a pivotal role in tumor progression.	SIRPB1 SIRPG	4.95e-05	3	142	2	23504854
Pubmed	SIRPα signaling regulates podocyte structure and function.	SIRPB1 SIRPG	4.95e-05	3	142	2	23842779
Pubmed	Essential roles of SIRPα in homeostatic regulation of skin dendritic cells.	SIRPB1 SIRPG	4.95e-05	3	142	2	20955735
Pubmed	Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis.	SIRPB1 SIRPG	4.95e-05	3	142	2	35634325
Pubmed	The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family.	SIRPB1 SIRPG	4.95e-05	3	142	2	9348339
Pubmed	Targeting SIRP-α protects from type 2-driven allergic airway inflammation.	SIRPB1 SIRPG	4.95e-05	3	142	2	21108471
Pubmed	Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.	SIRPB1 SIRPG	4.95e-05	3	142	2	16920950
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation.	SIRPB1 SIRPG	4.95e-05	3	142	2	17109464
Pubmed	Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.	SIRPB1 SIRPG	4.95e-05	3	142	2	23504624
Pubmed	Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.	SIRPB1 SIRPG	4.95e-05	3	142	2	25236797
Pubmed	Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.	SIRPB1 SIRPG	4.95e-05	3	142	2	33795678
Pubmed	Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.	SIRPB1 SIRPG	4.95e-05	3	142	2	17617577
Pubmed	Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation.	SIRPB1 SIRPG	4.95e-05	3	142	2	29914984
Pubmed	SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility.	SIRPB1 SIRPG	4.95e-05	3	142	2	11118207
Pubmed	Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy.	SIRPB1 SIRPG	4.95e-05	3	142	2	34050181
Pubmed	Ectodomain shedding of SHPS-1 and its role in regulation of cell migration.	SIRPB1 SIRPG	4.95e-05	3	142	2	15123722
Cytoband	22q11.21	RIMBP3 AIFM3 RIMBP3C RIMBP3B	4.07e-04	111	142	4	22q11.21
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	TCTA ABHD14B ITIH1 DNAH1 SCAP PLXNB1	4.74e-04	316	142	6	chr3p21
GeneFamily	Collagens	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	3.55e-06	46	92	5	490
GeneFamily	Fibronectin type III domain containing	EPHB6 VWA1 PTPRS MERTK TNXB CNTN2	1.66e-04	160	92	6	555
GeneFamily	CD molecules\|V-set domain containing\|C1-set domain containing\|Signal regulatory proteins	SIRPB1 SIRPG	2.54e-04	5	92	2	747
GeneFamily	Plexins	PLXNB1 PLXNB3	9.01e-04	9	92	2	683
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	1.12e-03	10	92	2	830
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN	SEMA6C RPGRIP1 MGAM SLC4A7 COL19A1 DTX1 SLC1A5 SIRPG ADAMTS10 KLHL3 SSC4D SIGIRR RASA4 LRP5 PYGL FUCA1	2.52e-06	740	141	16	M41202
Coexpression	NABA_COLLAGENS	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	3.43e-06	43	141	5	MM17060
Coexpression	NABA_COLLAGENS	COL4A3 COL13A1 COL19A1 COL24A1 COL1A2	3.85e-06	44	141	5	M3005
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE	THEMIS2 ENTPD7 EIF4A3 C15orf39 SLC1A5 PTGS2 TIAM2 BTBD3 NRP1 TXNRD1 COL24A1 PTPRS RRP12 MYO1F IQSEC1 COBL FTL MERTK DHTKD1 UAP1L1	1.25e-05	1250	141	20	M41099
Coexpression	GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_UP	TEX2 MCOLN1 NRP1 TRIM32 SIGIRR FAM222B HHAT UAP1L1	1.28e-05	199	141	8	M9531
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL19A1 TMPRSS6 POLR2A DNAH1 COL24A1 FTL HYDIN	1.15e-06	169	141	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 EIF4A3 SLC1A5 NRP1 COL24A1 PTPRS COBL	2.18e-06	186	141	7	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 EIF4A3 SLC1A5 NRP1 COL24A1 PTPRS COBL	2.18e-06	186	141	7	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	mild-Myeloid-Neutrophils_3\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM SIRPB1 PTGS2 FBXL5 MYO1F PYGL FTL	2.99e-06	195	141	7	a1cfed0092debcc003eff6a62508556b7664d5e1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FKBP10 COL13A1 DST OLFML1 PTPRS TNXB COL1A2	2.99e-06	195	141	7	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FKBP10 COL13A1 DST OLFML1 PTPRS TNXB COL1A2	2.99e-06	195	141	7	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FKBP10 COL13A1 DST OLFML1 PTPRS TNXB COL1A2	3.09e-06	196	141	7	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	mild-Myeloid-Neutrophils_4\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM SIRPB1 PTGS2 FBXL5 MYO1F PYGL FTL	3.09e-06	196	141	7	f8c98cded5550843322b1711e1a57c7e88cae861
ToppCell	mild-Myeloid\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THEMIS2 SIRPB1 PTGS2 FBXL5 MYO1F PYGL FTL	3.30e-06	198	141	7	908746384e10c6b833bb3bc124045d7b0bfd73b5
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MGAM CPD PTGS2 FBXL5 MYO1F PYGL FTL	3.41e-06	199	141	7	86f2857ce60fbe59375411373ff49c684fd66ad0
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FKBP10 COL13A1 NMNAT3 DST OLFML1 TNXB COL1A2	3.53e-06	200	141	7	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FKBP10 COL13A1 NMNAT3 DST OLFML1 TNXB COL1A2	3.53e-06	200	141	7	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	wk_20-22-Mesenchymal-Fibroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FKBP10 COL13A1 SLC1A5 DST MGST3 OLFML1 COL1A2	3.53e-06	200	141	7	94bd00fb6ff0dcb668eb36ec2085f1c3128855b6
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pro-B\|bone_marrow / Manually curated celltypes from each tissue	PPFIBP1 DTX1 VWA1 BTBD3 COL24A1 LRP5	1.05e-05	156	141	6	b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCell	356C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	FKBP10 COL24A1 PTPRS HHAT COBL PLXNB1	1.35e-05	163	141	6	ae9c5eb19657ea94b7f2357cbc8679acd697b8fe
ToppCell	356C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FKBP10 COL24A1 PTPRS HHAT COBL PLXNB1	1.40e-05	164	141	6	fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV2 SIRPG MYO1F AIFM3 HERC1 UAP1L1	1.60e-05	168	141	6	235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	ENTPD7 NRP1 COL24A1 PTPRS LRP5 CFAP61	1.71e-05	170	141	6	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 RPGRIP1 TEX2 NRP1 PTPRS EEPD1	1.77e-05	171	141	6	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TEX2 NRP1 COL24A1 PTPRS COBL DHTKD1	1.77e-05	171	141	6	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TEX2 NRP1 COL24A1 PTPRS COBL DHTKD1	1.77e-05	171	141	6	debbb071d260639b16269c94d172766908325c58
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 RPGRIP1 TEX2 NRP1 PTPRS EEPD1	1.77e-05	171	141	6	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 DTX1 ETV4 BDNF CSPG4 DHTKD1	1.89e-05	173	141	6	2b448acd5e584f24567204c31b8d74715e92f32a
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 DTX1 ETV4 BDNF CSPG4 DHTKD1	1.89e-05	173	141	6	5086edc29c5a6137ca09877929a1317f9739c801
ToppCell	343B-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TEX2 SIRPG COL24A1 PTPRS HHAT IQSEC1	2.02e-05	175	141	6	b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	PTGS2 NRP1 COL24A1 PTPRS LRP5 COBL	2.02e-05	175	141	6	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SIRPB1 NRP1 COL24A1 DST PTPRS COBL	2.08e-05	176	141	6	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL13A1 NRP1 DST OLFML1 PTPRS COL1A2	2.15e-05	177	141	6	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL13A1 NRP1 DST OLFML1 PTPRS COL1A2	2.15e-05	177	141	6	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	TRIM46 RPGRIP1 PPFIBP1 BTBD3 ADAMTS10 KLHL3	2.29e-05	179	141	6	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Macrophage\|bone_marrow / Manually curated celltypes from each tissue	NRP1 SSC4D DST EEPD1 FTL FUCA1	2.44e-05	181	141	6	d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 SLC1A5 PTGS2 ADAMTS10 TNXB COL1A2	2.52e-05	182	141	6	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM COL19A1 DNAH1 COL24A1 HYDIN CNTN2	2.67e-05	184	141	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM COL19A1 DNAH1 COL24A1 HYDIN CNTN2	2.67e-05	184	141	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM COL19A1 DNAH1 COL24A1 HYDIN CNTN2	2.67e-05	184	141	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	TEX2 NRP1 COL24A1 PTPRS COBL DHTKD1	2.67e-05	184	141	6	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A3 PPFIBP1 BDNF ABLIM1 DST COBL	2.76e-05	185	141	6	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	COL4A3 PTGS2 BDNF ABLIM1 DST COBL	2.76e-05	185	141	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM TMPRSS6 PTGS2 ABLIM1 TNXB COL1A2	2.76e-05	185	141	6	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	control-Myeloid-pDC\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TEX2 SLC1A5 NRP1 COL24A1 PTPRS COBL	2.84e-05	186	141	6	fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 SLC1A5 PTGS2 ADAMTS10 TNXB COL1A2	2.84e-05	186	141	6	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TEX2 SLC1A5 NRP1 COL24A1 PTPRS COBL	2.84e-05	186	141	6	330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|Dendritic_cell / Lineage, cell class and subclass	NRP1 COL24A1 PTPRS HHAT LRP5 COBL	2.84e-05	186	141	6	858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 SLC1A5 PTGS2 ADAMTS10 TNXB COL1A2	2.84e-05	186	141	6	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGD COL19A1 NRP1 ABLIM1 MGST3 COBL	2.84e-05	186	141	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	ENTPD7 SLC4A7 GATAD2B ARID1B SCAP HHAT	2.93e-05	187	141	6	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	COL4A3 PPFIBP1 BDNF ABLIM1 DST COBL	2.93e-05	187	141	6	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	FKBP10 SLC4A7 VWA1 NRP1 RASA4 RASA4B	2.93e-05	187	141	6	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL4A3 TXNRD1 COL24A1 PTPRS TNXB COL1A2	3.39e-05	192	141	6	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HGD TMPRSS6 F11 ITIH1 DST COBL	3.39e-05	192	141	6	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SEMA6C NRP1 COL24A1 DST CSPG4 SLC4A10	3.39e-05	192	141	6	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 SLC4A7 DTX1 F11 ABLIM1 PRDM16	3.39e-05	192	141	6	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	Severe-Myeloid-Macrophages-FABP4+\|Severe / Condition, Lineage, Cell class and cell subclass	NRP1 DST MGST3 FTL FUCA1 ACOT2	3.39e-05	192	141	6	30aad927ad40d8abaf9d0539bf8cb9d88d16f24d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 SLC4A7 DTX1 F11 COL24A1 KLHL21	3.39e-05	192	141	6	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	COL19A1 SRPK2 NRP1 ARID1B TNRC6A VPS13B	3.39e-05	192	141	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ENTPD7 CPD MED1 MGA MED13 VPS13B	3.49e-05	193	141	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	control-Lymphocytic-CD4_T_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM SIRPB1 PTGS2 MYO1F PYGL FTL	3.60e-05	194	141	6	c2ae2ea848d78725455dcb6be9f1d8933745fa80
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM CPD PTGS2 FBXL5 MYO1F FTL	3.60e-05	194	141	6	4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	FKBP10 COL13A1 DST OLFML1 CSPG4 COL1A2	3.60e-05	194	141	6	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	PPFIBP1 CEP76 KIAA1191 BTBD3 TREH NMT2	3.70e-05	195	141	6	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 SLC1A5 ADAMTS10 OLFML1 TNXB COL1A2	3.70e-05	195	141	6	613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 SLC1A5 ADAMTS10 OLFML1 TNXB COL1A2	3.70e-05	195	141	6	9ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	COL4A3 TXNRD1 COL24A1 ARID1B PTPRS COL1A2	3.70e-05	195	141	6	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	(2)_5-FU\|World / Stress and Cell class	FKBP10 NRP1 MGST3 FTL POFUT2 COL1A2	3.70e-05	195	141	6	e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A7 TMPRSS6 DST XRN1 HERC1 MGA	3.70e-05	195	141	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM CPD PTGS2 FBXL5 MYO1F IQSEC1	3.81e-05	196	141	6	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A3 SLC4A7 CPD ABLIM1 DST PRDM16	3.81e-05	196	141	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	BL-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGAM CPD PTGS2 FBXL5 PYGL FTL	3.81e-05	196	141	6	f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL13A1 DST OLFML1 PTPRS TNXB COL1A2	3.81e-05	196	141	6	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	control-Others-Megakaryocytes\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM SIRPB1 PTGS2 MYO1F PYGL FTL	3.81e-05	196	141	6	10d914f1612622f64ac71da04e1995a854a4bec9
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPD PTGS2 FBXL5 KLHL21 MYO1F FTL	3.81e-05	196	141	6	d9b5eaca4089d5337f1175a663418c9c675cdd87
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM CPD PTGS2 FBXL5 MYO1F IQSEC1	3.81e-05	196	141	6	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL13A1 DST OLFML1 PTPRS TNXB COL1A2	3.81e-05	196	141	6	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	(7)_Macrophage\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MCOLN1 DST PYGL FTL FUCA1 MERTK	3.81e-05	196	141	6	f1c822860d2a0bae84b0263b0151185756423e0f
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A3 TXNRD1 COL24A1 ARID1B PTPRS COL1A2	3.81e-05	196	141	6	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	BL-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGAM CPD SIRPB1 PTGS2 PYGL FTL	3.92e-05	197	141	6	932a7fae4979b561688e6222505df0f4e510ab11
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL13A1 NRP1 DST OLFML1 TNXB COL1A2	3.92e-05	197	141	6	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL13A1 DST OLFML1 PTPRS TNXB COL1A2	3.92e-05	197	141	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A3 PPFIBP1 BDNF ABLIM1 DST COBL	3.92e-05	197	141	6	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	ASK452-Epithelial-Type_1\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	IGSF8 COL4A3 PTGS2 BDNF ABLIM1 DST	3.92e-05	197	141	6	dc0a6dca4af6b216357b06f67203274f8b2a8bb0
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	FKBP10 COL13A1 DST OLFML1 TNXB COL1A2	3.92e-05	197	141	6	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPD PTGS2 FBXL5 KLHL21 MYO1F FTL	3.92e-05	197	141	6	037f5f26fa66818baa35846aa96336155e8a6f45
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THEMIS2 NRP1 MYO1F FTL FUCA1 MERTK	3.92e-05	197	141	6	e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM CPD SIRPB1 PTGS2 FBXL5 MYO1F	3.92e-05	197	141	6	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL13A1 NRP1 DST OLFML1 TNXB COL1A2	3.92e-05	197	141	6	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	ASK440-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	COL4A3 PPFIBP1 PTGS2 BDNF ABLIM1 DST	3.92e-05	197	141	6	782449c522c9e16e72bf999a73090688a3aefe06
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM CPD PTGS2 FBXL5 MYO1F IQSEC1	3.92e-05	197	141	6	3cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell	NS-critical-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CPD SIRPB1 PTGS2 FBXL5 MYO1F FTL	3.92e-05	197	141	6	f38037dfa6c33e9336130d0cc65eaba0f120efb9
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL13A1 DST OLFML1 PTPRS TNXB COL1A2	3.92e-05	197	141	6	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FKBP10 BDNF CSPG4 COBL TNXB PLXNB1	4.03e-05	198	141	6	5cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
ToppCell	15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	FKBP10 COL13A1 NRP1 OLFML1 FTL COL1A2	4.03e-05	198	141	6	3d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MGAM CPD PTGS2 MYO1F PYGL FTL	4.03e-05	198	141	6	e76061e66f6d60f5735962aa7777dda8958caed9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FKBP10 BDNF CSPG4 COBL TNXB PLXNB1	4.03e-05	198	141	6	ff6d9455ebfe965cc6f48197172c0ebd3bddde81
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FKBP10 BDNF CSPG4 COBL TNXB PLXNB1	4.03e-05	198	141	6	5375a2895cf995f0db4a61861093f01794707901
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)\|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NRP1 DST MGST3 FTL FUCA1 MERTK	4.03e-05	198	141	6	ff9c97c6f579a4e79859d420f224556fadc1f6ab
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM SIRPB1 PTGS2 MYO1F PYGL FTL	4.03e-05	198	141	6	c4a004f211f72f28aacbb512c6e075cbd049be53
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CPD SIRPB1 FBXL5 MYO1F PYGL FTL	4.03e-05	198	141	6	9b29232c8b4dcbd81f450f47c3f79bf26c8fb583
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	SLC4A7 VWA1 NRP1 RASA4 RRP12 RASA4B	4.03e-05	198	141	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MCOLN1 NRP1 DST FTL FUCA1 MERTK	4.03e-05	198	141	6	9aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FKBP10 BDNF CSPG4 COBL TNXB PLXNB1	4.03e-05	198	141	6	35edf6d5bedc2181fbdd56f43e458bc39f4eca16
Drug	AC1LAKND	COL4A3 COL13A1 COL19A1 COL24A1 DST ALDH4A1 COL1A2	8.26e-08	62	135	7	CID000470146
Drug	chondroitin sulfate	EPHB6 COL4A3 COL13A1 COL19A1 F11 NRP1 SIRPG COL24A1 DST CSPG4 TNXB CNTN2 PLXNB3 COL1A2	1.75e-07	413	135	14	CID000024766
Drug	hydroxylysine	COL4A3 MGAM COL13A1 COL19A1 COL24A1 DST MUC5AC COL1A2	2.85e-07	109	135	8	CID000001029
Drug	d-indobufen	COL4A3 COL13A1 PTGS2 COL24A1 DST COL1A2	4.98e-07	50	135	6	CID000044562
Drug	ridogrel	COL4A3 COL13A1 PTGS2 COL24A1 DST COL1A2	6.32e-07	52	135	6	CID005362391
Drug	4-hydroxyproline	COL4A3 COL13A1 COL19A1 COL24A1 DST ALDH4A1 COL1A2	1.18e-06	91	135	7	CID000000825
Drug	GK-101	COL4A3 COL13A1 COL24A1 DST COL1A2	2.21e-06	36	135	5	CID000161853
Drug	homonojirimycin	MGAM TREH PYGL FUCA1	2.65e-06	17	135	4	CID000159496
Drug	ticlopidine	COL4A3 COL13A1 COL19A1 PTGS2 COL24A1 DST COL1A2	2.72e-06	103	135	7	CID000005472
Drug	hyaluronan	COL4A3 COL13A1 COL19A1 PTGS2 ITIH1 COL24A1 DST TNXB VPS13B COL1A2	3.96e-06	263	135	10	CID000024759
Drug	BAPN	COL4A3 COL13A1 COL19A1 COL24A1 DST COL1A2	4.06e-06	71	135	6	CID000001647
Drug	AC1NMZ1B	COL4A3 COL13A1 PTGS2 COL24A1 DST COL1A2	5.59e-06	75	135	6	CID005034185
Drug	Tranilast sodium	COL4A3 COL13A1 COL19A1 PTGS2 COL24A1 DST COL1A2	5.67e-06	115	135	7	CID000005527
Drug	Madecassol	COL4A3 COL13A1 COL24A1 DST COL1A2	7.67e-06	46	135	5	CID000108062
Drug	NSC624987	MGAM TREH AGL FUCA1	7.96e-06	22	135	4	CID000001472
Drug	ginsenoside	MGAM TREH AGL PYGL	9.59e-06	23	135	4	CID000092797
Drug	halofuginone lactate	COL4A3 COL13A1 COL19A1 COL24A1 DST COL1A2	1.16e-05	85	135	6	CID000062891
Drug	DMSe	COL4A3 MGAM COL13A1 COL24A1 DST TNXB COL1A2	1.40e-05	132	135	7	CID000020796
Drug	NSC49633	COL4A3 COL13A1 COL24A1 DST COL1A2	1.55e-05	53	135	5	CID000023340
Drug	PCR 4099	COL4A3 COL13A1 COL19A1 PTGS2 COL24A1 DST COL1A2	1.96e-05	139	135	7	CID000002806
Drug	AC1L18QD	COL4A3 MGAM COL13A1 COL19A1 PTGS2 BDNF COL24A1 DST TRIM32 COL1A2	2.49e-05	325	135	10	CID000000213
Drug	glucosyl fluoride	MGAM TREH PYGL	3.25e-05	11	135	3	CID000150967
Drug	3 Cu	MGAM TREH	3.49e-05	2	135	2	CID009859098
Drug	AC1L1C2F	COL4A3 COL13A1 COL24A1 DST MUC5AC COL1A2	5.02e-05	110	135	6	CID000001711
Drug	methyl 1'-epiacarviosin	MGAM TREH PYGL	5.58e-05	13	135	3	CID000197426
Drug	MDL 25,637	MGAM TREH FUCA1	5.58e-05	13	135	3	CID000128548
Drug	PPACK	COL4A3 COL13A1 F11 COL24A1 DST COL1A2	5.84e-05	113	135	6	CID003036757
Drug	malotilate	COL4A3 COL13A1 COL24A1 DST COL1A2	6.47e-05	71	135	5	CID000004006
Drug	khellin	COL4A3 COL13A1 COL19A1 COL24A1 DST PRDM16 COL1A2	7.37e-05	171	135	7	CID000003828
Drug	AC1OAGYH	MGAM TREH FUCA1	8.80e-05	15	135	3	CID006857622
Disease	cognitive function measurement, self reported educational attainment	SRPK2 DPP8 ITIH1 GATAD2B ARID1B TNRC6A SLC4A10 TNXB	1.84e-04	355	130	8	EFO_0004784, EFO_0008354
Disease	respiratory failure, COVID-19	CPD DST CFAP61	2.81e-04	29	130	3	EFO_0009686, MONDO_0100096
Disease	Epilepsy, Cryptogenic	BDNF TXNRD1 ARID1B SLC4A10	4.82e-04	82	130	4	C0086237
Disease	Awakening Epilepsy	BDNF TXNRD1 ARID1B SLC4A10	4.82e-04	82	130	4	C0751111
Disease	Aura	BDNF TXNRD1 ARID1B SLC4A10	4.82e-04	82	130	4	C0236018
Disease	cystitis (implicated_via_orthology)	PTGS2 BDNF	5.30e-04	8	130	2	DOID:1679 (implicated_via_orthology)
Disease	tyrosine-protein kinase receptor TYRO3 measurement	MGAM MGA	5.30e-04	8	130	2	EFO_0020829
Disease	feeling nervous measurement	MGAM ITIH1 BDNF MGA	6.03e-04	87	130	4	EFO_0009597
Disease	Ehlers-Danlos syndrome (is_implicated_in)	TNXB COL1A2	6.80e-04	9	130	2	DOID:13359 (is_implicated_in)
Disease	signal-regulatory protein beta-1 measurement	SIRPB1 SIRPG	6.80e-04	9	130	2	EFO_0802069
Disease	immature reticulocyte measurement	TMPRSS6 FAM222B LRP5	7.33e-04	40	130	3	EFO_0803545
Disease	Melancholia	PTGS2 BDNF FTL	7.88e-04	41	130	3	C0025193
Disease	Depression, Neurotic	PTGS2 BDNF FTL	7.88e-04	41	130	3	C0282126
Disease	Depressive Syndrome	PTGS2 BDNF FTL	8.46e-04	42	130	3	C0086133
Disease	Short Stature, CTCAE	EIF4A3 IQSEC1	8.47e-04	10	130	2	C2919142
Disease	Short stature	EIF4A3 IQSEC1	8.47e-04	10	130	2	C0349588
Disease	Osteogenesis imperfecta type IV (disorder)	FKBP10 COL1A2	8.47e-04	10	130	2	C0268363
Disease	Osteogenesis imperfecta type III (disorder)	FKBP10 COL1A2	1.03e-03	11	130	2	C0268362
Disease	Endogenous depression	PTGS2 BDNF FTL	1.10e-03	46	130	3	C0011573
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	EGLN2 BDNF	1.24e-03	12	130	2	C1861063
Disease	Epilepsy	BDNF TXNRD1 ARID1B SLC4A10	1.40e-03	109	130	4	C0014544
Disease	pulmonary fibrosis (biomarker_via_orthology)	PTGS2 MUC5AC COL1A2	1.41e-03	50	130	3	DOID:3770 (biomarker_via_orthology)
Disease	rhinitis (biomarker_via_orthology)	BDNF MUC5AC	1.46e-03	13	130	2	DOID:4483 (biomarker_via_orthology)
Disease	gastric ulcer (implicated_via_orthology)	PTGS2 MUC5AC	1.69e-03	14	130	2	DOID:10808 (implicated_via_orthology)
Disease	diabetic neuropathy (implicated_via_orthology)	PTGS2 BDNF	1.69e-03	14	130	2	DOID:9743 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A10	1.95e-03	15	130	2	DOID:2355 (implicated_via_orthology)
Disease	Obesity	SUCLA2 PTGS2 NHLH2 FTL VPS13B	2.19e-03	205	130	5	C0028754
Disease	response to radiation, Urinary retention	PLK5 PTPRS	2.51e-03	17	130	2	GO_0009314, HP_0000016
Disease	glaucoma (implicated_via_orthology)	BDNF NMNAT3	2.51e-03	17	130	2	DOID:1686 (implicated_via_orthology)
Disease	Oral Submucous Fibrosis	PTGS2 COL1A2	2.81e-03	18	130	2	C0029172
Disease	waist-hip ratio	THEMIS2 DTX1 SRPK2 BDNF NRP1 ADAMTS10 COL24A1 PTPRS TNRC6A XRN1 CLDN20 PRDM16 CNTN2	3.01e-03	1226	130	13	EFO_0004343
Disease	alcohol consumption measurement	ENTPD7 MGAM MED1 BDNF BTBD3 FZD7 TNRC6A XRN1 SLC4A10 COBL DMRTA2 MGA PRDM16	3.36e-03	1242	130	13	EFO_0007878
Disease	Intellectual Disability	EIF4A3 BDNF IQSEC1 SLC4A10 ALDH4A1 FUCA1 MED13	3.74e-03	447	130	7	C3714756
Disease	Osteogenesis imperfecta	FKBP10 COL1A2	3.83e-03	21	130	2	cv:C0029434
Disease	status epilepticus (implicated_via_orthology)	PTGS2 BDNF	3.83e-03	21	130	2	DOID:1824 (implicated_via_orthology)
Disease	Manic Disorder	SRPK2 ITIH1 BDNF	3.84e-03	71	130	3	C0024713
Disease	migraine disorder, endometriosis	COL13A1 POLR2A NRP1	4.15e-03	73	130	3	EFO_0001065, MONDO_0005277
Disease	progression free survival, ovarian serous carcinoma	MGAM MGA	4.20e-03	22	130	2	EFO_0004920, EFO_1001516
Disease	Leber Congenital Amaurosis	RPGRIP1 MERTK	4.20e-03	22	130	2	C0339527

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLHGVTFGYQGQKPL	ABCF1	626	Q8NE71
EGNPLLKHYRGPAGD	SLC1A5	516	Q15758
KGAKIQGGILPGSYH	CFAP61	1036	Q8NHU2
YGGNIDHKISHLGTP	ASB9	156	Q96DX5
IRGQGGLAYPGVRTH	BDNF	26	P23560
LIQGPQYGHLLVGGR	CSPG4	1981	Q6UVK1
IHGLQGDKGEPGYSE	COL4A3	1046	Q01955
SKTASLPGYGRNGLH	ABLIM1	651	O14639
HYGAPLVKGVLSRGR	AIFM3	111	Q96NN9
DTGGHRGYVPAGKLQ	ARHGEF37	551	A1IGU5
ANVGGTLHYKGETLP	ACOT2	321	P49753
GTQRLPGHKYVLAVG	BTBD3	131	Q9Y2F9
SGTNDKPGGPHYILR	ALDH4A1	526	P30038
GRYEHPGLGALGTQQ	ARID1B	281	Q8NFD5
LGYERAPVIGGGGKQ	CEP76	346	Q8TAP6
GGLDYLVLNHIGGAP	HSD11B1L	106	Q7Z5J1
SGIVILLPHGYDGAG	DHTKD1	691	Q96HY7
AAAAVHKEPTYGGGL	DMRTA2	516	Q96SC8
NGHGKLAGPSPYLGR	EEPD1	376	Q7L9B9
YPHLGQKPGGSDFLR	ARPP19	36	P56211
YLIEPLHGGPKGSRS	ADAMTS10	156	Q9H324
NKHEPGGAIYIGFIS	CLDN20	156	P56880
GVNGHRYPGAGVVIK	ETV4	246	P43268
TGLLGSYHPGVFRGD	RASA4	676	O43374
TGLLGSYHPGVFRGD	RASA4B	676	C9J798
YGELGGHRGLVPAHL	RIMBP3B	1616	A6NNM3
YGELGGHRGLVPAHL	RIMBP3C	1616	A6NJZ7
LITGAYDTIKHPGGA	MCOLN1	516	Q9GZU1
GYRAVAIDLPGLGHS	ABHD14B	61	Q96IU4
IGRDYKGVLQAGGLP	FOXB2	276	Q5VYV0
ETEHAKGSPGGYLGA	NMT2	31	O60551
IGGRYHGPTFAKAAQ	ENTPD7	431	Q9NQZ7
PGDKIGLHLRGGYIF	MGAM2	756	Q2M2H8
RERLHGGKGLPFYAG	MGA	1441	Q8IWI9
SPGQHDGTYFGRLGI	ITIH1	721	P19827
DSKPHEGRYILNGGS	MERTK	921	Q12866
LAEYAPNLRGSGVHG	PPFIBP1	821	Q86W92
LRLPGYLSGKGFHSG	DST	7451	Q03001
NLHRLGGPEAGLGEY	FTL	151	P02792
LPGDKIGLHLRGGYI	MGAM	806	O43451
AYERSLGGQQGSPKH	IQSEC1	406	Q6DN90
NGKLGHGDTNRVYKP	HERC1	591	Q15751
GRGGVPLYDRNHVTG	LRP5	1466	O75197
RKLDYGQHVVAGTPG	EIF4A3	151	P38919
AGGGSYKGHVDILAP	DDX1	696	Q92499
RGLGYHGEKLQPFGQ	GPATCH3	451	Q96I76
GQLHRVYLGPGSDGH	PLXNB1	426	O43157
HLALAPGRGTLYVGA	PLXNB3	56	Q9ULL4
YGAKEGGISRLPAGQ	KAT14	526	Q9H8E8
KHAAGRELAGPGFVG	FAM222B	391	Q8WU58
LGGNYLLNIGPTKDG	FUCA1	331	P04066
FGYQLLDGGRTGRHP	PLK5	216	Q496M5
KRGPAFTNGLGHGVD	PTGS2	201	P35354
AVVVLSGPHRGLYGK	GPKOW	246	Q92917
SGPHRGLYGKVEGLD	GPKOW	251	Q92917
HPGSLEPAREAGKGY	GOLGA6L7	561	A0A1B0GV03
GPHGGDKETYNNIIR	MUC5AC	1761	P98088
GPHGGDKETYNNIIR	MUC5AC	3971	P98088
GGHKGPSLADRQREY	GATAD2B	561	Q8WXI9
AVGGVYHPRIASGLG	MGST3	76	O14880
GLRDAGYTPHKGLTT	KIAA1191	126	Q96A73
ASGYEGVLRHKGVRP	DTX1	421	Q86Y01
LLPGGVGRALVYQHS	OLFML1	251	Q6UWY5
KQYGGFDNRGLEPGH	PTPRS	1226	Q13332
GSIVGRNQSYPGEKH	FADS2B	11	A8MWK0
NGKGSLKGQPGDIYH	GBA	231	P04062
YIPVGGSQHGLLGTL	HHAT	351	Q5VTY9
GPHIGRYCGQKTPGR	NRP1	221	O14786
LSAGAGAQPYHGEKG	FZD7	26	O75084
VQVGTHRGLEYNPGK	DNAH1	26	Q9P2D7
HRGLEYNPGKILPGS	DNAH1	31	Q9P2D7
QPGHKGERGYPGNIG	COL1A2	941	P08123
HLAYGENGTGDKIPG	FKBP10	346	Q96AY3
LRIPGDGLGHKSISY	HYDIN	601	Q4G0P3
GVGSLGPGYEGRHIA	IGSF8	366	Q969P0
PDHLGGGYSIVALGN	KLHL21	321	Q9UJP4
YRGQKGERGEPGIGL	COL19A1	1076	Q14993
GKYTQHGGGNASRPA	GAB4	316	Q2WGN9
QAGSGIYHVKDGGPQ	DPP8	181	Q6V1X1
RGQNPGKSYRLKHGL	COBL	691	O75128
EGGMLYPQGTHLLLG	FSCN3	231	Q9NQT6
QTKEGGYFHVLLAPG	CPD	1241	O75976
PTKILHGRGGISGYT	F11	356	P03951
PGGHYRRTNVKETIG	CNTN2	556	Q02246
QLYATGGHDGPLVRK	KLHL3	491	Q9UH77
LGGGLPYLEHLNLSG	FBXL5	621	Q9UKA1
GLGYVRHVDNPHGDG	EGLN2	291	Q96KS0
GDPGIQGYHGRKGER	COL13A1	306	Q5TAT6
PGLHAGGTTSLKRYQ	ETV2	196	O00321
GPGGVQAHGDVTLYK	SCAP	696	Q12770
LRHKEPGSGSGGGVY	EXOSC3	86	Q9NQT5
NAGPLDKILHGSVGY	MED1	196	Q15648
IRGHYEAKQGGFLPG	HGD	346	Q93099
VIKRKGGGHVAYGPQ	RTP5	481	Q14D33
HFPKGGGYSVLIREG	TRIM32	601	Q13049
GTYPGRKRGALHPQV	TRIM46	111	Q7Z4K8
EAGQYRSKRKPPHGG	RPGRIP1	976	Q96KN7
LLGPAGKAPQYHEIG	SLC4A7	471	Q9Y6M7
GSALGGPYLGVHLRR	POFUT2	281	Q9Y2G5
YGELGGHRGLVPAHL	RIMBP3	1616	Q9UFD9
GLGLLYFHGKGVPLN	SEL1L2	376	Q5TEA6
NGGGREPRKNHVYGE	PRDM16	816	Q9HAZ2
HVYGERKLGAGEGLP	PRDM16	826	Q9HAZ2
RARTAAGHGPYGGKV	EPHB6	561	O15197
GDGKGGSRAALYPHP	NHLH2	46	Q02577
KDGLPLGIGGHYSLH	SIGIRR	51	Q6IA17
YPHGGDAGKGQSTDR	MED13	2031	Q9UHV7
FRGPSGLLTYTGKGH	CYB5R1	146	Q9UHQ9
GPGRELIYNQKEGHF	SIRPG	71	Q9P1W8
KLHGGTPANFLDVGG	SUCLA2	336	Q9P2R7
QYQAGGSGIHRPVAK	RRP12	1211	Q5JTH9
HKYVRGENGPGGFIV	STARD3	376	Q14849
AGPGRELIYNQKEGH	SIRPB1	71	Q5TFQ8
VGISGYHRLKEGAVP	THAP7	76	Q9BT49
ALPLQPLGGHKGTGY	C15orf39	301	Q6ZRI6
LLGPKGIQGYHGADG	COL24A1	1286	Q17RW2
GLGALRGDGYLHPVK	TCF24	116	Q7RTU0
GGHGPTLKAYQEGRL	TXNRD1	131	Q16881
ALGYHVQFGPLRGGE	VWA1	361	Q6PCB0
QRGGLITHSRPYKGE	ZNF567	221	Q8N184
PDGLAYGEGLRKGNE	TIAM2	926	Q8IVF5
GHAGVPRESARGLYK	SPEM3	131	A0A1B0GUW6
GNTVTGLYHRPGLGG	TCTA	61	P57738
LGHFGYGRGPVLLDN	SSC4D	396	Q8WTU2
ELERLYSHFAGGGGP	UFSP1	46	Q6NVU6
GARPEGGARQGHYVI	SPRED3	36	Q2MJR0
TKEKGHGGCGRYQPR	POLR2A	176	P24928
PRHFLVSGGYQGKLR	THEMIS2	311	Q5TEJ8
GPLGKGQQYHEIGRS	SLC4A10	376	Q6U841
GGYHPVKIGDLFNGR	SRPK2	66	P78362
LYGFHGGQRVGPVSA	TNXB	2371	P22105
LYGFHGGQRVGPISV	TNXB	2696	P22105
LDLVKTYGHVPNGGR	TREH	201	O43280
LGGYINESGHLNLPR	XRN1	321	Q8IZH2
LAGGQGTRLGVTYPK	UAP1L1	111	Q3KQV9
SGGPGKHLLYLGRPE	SEMA6C	876	Q9H3T2
LYGLRGPHKADSIQG	TNXA	221	Q16473
GRNHYIPLVGIKGAA	VCPIP1	351	Q96JH7
GYGILHGAGLSQLPK	VPS13B	3821	Q7Z7G8
YGKGIGYSSGLPRHQ	ZNF233	291	A6NK53
LPHYVSGLFLGIGLG	TEX2	491	Q8IWB9
LLPGAEGYVGGHRTS	TEX2	971	Q8IWB9
PRTVIIGGKAAPGYH	PYGL	601	P06737
LNIGDYNRTVGKGPG	TNRC6A	1246	Q8NDV7
HRFGGLVLSPVGKQY	TSR3	91	Q9UJK0
YVGQGQVLRLKGPDH	TMPRSS6	226	Q8IU80
YERLAGHGPKLGPVT	AGL	406	P35573
GRLHGQEGLFPGNYV	MYO1F	1081	O00160
GRVGHDPKGYIAESP	NMNAT3	166	Q96T66