Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentactin cytoskeleton

WHRN SHROOM3 SORBS2 MYLK KALRN INPP5D TRIOBP DGKH ASAP1 NPM3 SGPP1 MICALL2 AUTS2 SNX9

1.17e-0457615714GO:0015629
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

1.93e-06121514PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

1.93e-06121514IPR027970
DomainZF_CCHC_HIVEP

HIVEP1 HIVEP3

6.49e-0521512PS51811
DomainAUTS2

FBRSL1 AUTS2

1.94e-0431512IPR023246
DomainREKLES

ARID3A ARID3B

1.94e-0431512PS51486
DomainREKLES_domain

ARID3A ARID3B

1.94e-0431512IPR023334
Domain-

ARID3A ARID5A ARID3B

2.19e-041515131.10.150.60
DomainBRIGHT

ARID3A ARID5A ARID3B

2.19e-04151513SM00501
DomainARID_dom

ARID3A ARID5A ARID3B

2.19e-04151513IPR001606
DomainARID

ARID3A ARID5A ARID3B

2.19e-04151513PS51011
DomainARID

ARID3A ARID5A ARID3B

2.19e-04151513PF01388
DomainLAM_G_DOMAIN

COL27A1 LAMA4 EYS SLIT3

2.45e-04381514PS50025
DomainAT_hook

PRR12 BAZ2A SETBP1

2.69e-04161513PF02178
DomainFERM_f0

SHANK1 TLN1

3.85e-0441512PF16511
DomainFERM_f0

SHANK1 TLN1

3.85e-0441512IPR032425
DomainZF_ZZ_2

ZSWIM2 ZZEF1 NBR1

3.87e-04181513PS50135
DomainZF_ZZ_1

ZSWIM2 ZZEF1 NBR1

3.87e-04181513PS01357
DomainZZ

ZSWIM2 ZZEF1 NBR1

3.87e-04181513PF00569
DomainZnf_ZZ

ZSWIM2 ZZEF1 NBR1

4.56e-04191513IPR000433
DomainZnF_ZZ

ZSWIM2 ZZEF1 NBR1

4.56e-04191513SM00291
DomainNUT

NUTM2G NUTM2F

6.39e-0451512IPR024310
DomainNUT_N

NUTM2G NUTM2F

6.39e-0451512IPR024309
DomainNUT

NUTM2G NUTM2F

6.39e-0451512PF12881
Domain-

EPN3 GGA2 RPRD2

1.18e-032615131.25.40.90
DomainLaminin_G

COL27A1 LAMA4 EYS SLIT3

1.24e-03581514IPR001791
DomainAT_hook

PRR12 BAZ2A SETBP1

1.31e-03271513SM00384
DomainAT_hook_DNA-bd_motif

PRR12 BAZ2A SETBP1

1.31e-03271513IPR017956
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1

1.12e-116159520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1

1.12e-116159525930072
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DIP2B SHROOM3 TRIO NUMBL ZC3H8 MAN1C1 BICRA FBRSL1 TRIOBP DGKH ARHGAP39 SMOC2 ESCO1 KIAA1671 HIVEP3 JAK2 PHLDB1 PXDN SETBP1 NUP210 AUTS2 ZFHX2 RPRD2 SNX9 HECTD1 NBR1 AGAP3

9.31e-1014891592728611215
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 ZP2 SPATA31A6 SPATA31A5 SPATA31A1

1.04e-0924159632212159
Pubmed

Interaction network of human early embryonic transcription factors.

SOX5 HIVEP1 ARID3A BICRA DTL FBRSL1 NUP214 BCL9 POM121C KIAA1671 PRR12 NCOR1 AUTS2

9.69e-093511591338297188
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPN3 SHROOM3 ARID3A MAN2B1 TRIO KALRN BICRA FBRSL1 NUP214 BCL9 ZZEF1 POM121C HIVEP3 JAK2 PRR12 NCOR1 PHLDB1 TLN1 TIGD3 HECTD1 AGAP3

3.78e-0811051592135748872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SHROOM3 BICRA INPP5D NUP214 BCL9 POM121C ASAP1 NPM3 KIAA1671 NCOR1 TLN1 SETBP1 MRTFA

1.04e-074301591335044719
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

EPN3 SHROOM3 BCL9 POM121C PRR12 NCOR1 FIP1L1 RPRD2 LAMTOR1

1.59e-07180159935198878
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SOX5 SP2 HIVEP1 BICRA PCLO FBRSL1 ARID3B PRR12 ATF7IP AUTS2 NUTM2F SNX9

3.36e-073981591235016035
Pubmed

Human transcription factor protein interaction networks.

SOX5 SP2 HNF1B HIVEP1 ARID3A BICRA SEC24A FBRSL1 PPP1R13B NUP214 BCL9 POM121C NPM3 CCNA2 ARID3B KIAA1671 PRR12 NCOR1 ATF7IP AUTS2 FIP1L1 RPRD2

6.50e-0714291592235140242
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

DIP2B SORBS2 GGA2 KALRN PCLO PPP1R13B ARHGAP39 PHLDB1 MICALL2

7.98e-07218159933378226
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SHROOM3 GGA2 FBRSL1 TRIOBP SIK3 ZZEF1 NACAD SETBP1 SLIT3 AUTS2 RPRD2 IGSF1 NBR1

1.08e-065291591314621295
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

MYLK BICRA PANX2 ZP2 ASAP1 JAK2 RGS20 BAZ2A NR5A1 FOXJ1

3.08e-063291591017474147
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK1 SORBS2 TRIO NUMBL KALRN PCLO ARHGAP39 SIK3 ASAP1

6.38e-06281159928706196
Pubmed

Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.

NUP214 ARHGAP39 RNF157 BAZ2A

6.80e-0627159419026994
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TRIOBP SIK3 PHLDB1 TLN1 SETBP1 AUTS2 RPRD2 MRTFA

9.93e-06225159812168954
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DIP2B SHROOM3 SORBS2 HIVEP1 TRIO NUMBL SEC24A DTL SIK3 KIAA1671 PHLDB1 FIP1L1 SKA3 HECTD1 AGAP3

1.06e-058611591536931259
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID3A ARID5A ARID3B

1.10e-0510159315922553
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX5 SP2 KLF11 HIVEP1 NR4A1 HIVEP3 OLIG3 HOXD1 PROX2 SETBP1 ZFHX2 DMRTA2 NR5A1 ZNF541 FOXJ1

1.98e-059081591519274049
Pubmed

Changes in allele frequencies of CSF3R and SETBP1 mutations and evidence of clonal evolution in a chronic neutrophilic leukemia patient treated with ruxolitinib.

CSF3R SETBP1

2.08e-052159228209656
Pubmed

Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population.

NRG1 AUTS2

2.08e-052159229377512
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

2.08e-052159226858404
Pubmed

The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family.

ARID3A ARID3B

2.08e-05215928543152
Pubmed

The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly.

STMN2 RGS20

2.08e-052159211882662
Pubmed

ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells.

ARID3A ARID3B

2.08e-052159232061921
Pubmed

SALL4 and SF-1 are sensitive and specific markers for distinguishing granulosa cell tumors from yolk sac tumors.

SALL4 NR5A1

2.08e-052159222832114
Pubmed

Whole-exome sequence analysis highlights the role of unmasked recessive mutations in copy number variants with incomplete penetrance.

NUP214 NCOR1

2.08e-052159229483668
Pubmed

CXorf6 is a causative gene for hypospadias.

MAMLD1 NR5A1

2.08e-052159217086185
Pubmed

NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development.

MAMLD1 NR5A1

2.08e-052159227490115
Pubmed

A novel DFNB31 mutation associated with Usher type 2 syndrome showing variable degrees of auditory loss in a consanguineous Portuguese family.

WHRN EYS

2.08e-052159221738389
Pubmed

Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.

OLIG3 FIP1L1

2.08e-052159230157244
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

KALRN NELFA MAN1C1 DTL ADAR NCOR1 FIP1L1 RPRD2 PSRC1 MRTFA AGAP3

2.20e-055031591116964243
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ARID3A BCL9 ARID3B PRR12 NCOR1

4.08e-0583159528794006
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

NUP214 POM121C NUP210

4.10e-0515159314697343
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

PPP1R13B ADAR ARID3B KIAA1671 NCOR1 BAZ2A TLN1 RPRD2 SKA3 SNX9 TPD52

4.85e-055491591138280479
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

HNF1B SEC24A MAMLD1 NUP214 BCL9 POM121C PRR12 NCOR1 NUP210 AUTS2

5.20e-054571591032344865
Pubmed

ARID proteins come in from the desert.

ARID3A ARID3B

6.21e-053159210838570
Pubmed

Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene.

CRH NCOR1

6.21e-053159218006628
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

6.21e-053159231801062
Pubmed

Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway.

VEGFC NRG1

6.21e-053159212471041
Pubmed

Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CEL.

JAK2 FIP1L1

6.21e-053159222523564
Pubmed

The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain.

JAK2 CSF3R

6.21e-05315927775438
Pubmed

Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia.

CSF3R SETBP1

6.21e-053159228209919
Pubmed

CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia.

CSF3R SETBP1

6.21e-053159225316523
Pubmed

Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.

ARID3A ARID3B

6.21e-053159233649863
Pubmed

Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5.

SOX5 FOXJ1

6.21e-053159220668334
Pubmed

ASXL1 mutations are frequent and prognostically detrimental in CSF3R-mutated chronic neutrophilic leukemia.

CSF3R SETBP1

6.21e-053159225850813
Pubmed

The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.

ARID3A ARID3B

6.21e-053159221199920
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

BICRA FBRSL1 BCL9 PRR12 CEP20 AUTS2

7.43e-05152159638360978
Pubmed

A human MAP kinase interactome.

SHANK1 HIVEP1 BICRA LAMA4 PPP1R13B NUP214 SIK3 POM121C ASAP1 ATF7IP

8.65e-054861591020936779
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SOX5 SP2 KLF11 HIVEP1 ARID3A ZC3H8 SALL4 ARID3B HIVEP3 NCOR1 BRDT BAZ2A MRTFA

9.38e-058081591320412781
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WHRN SORBS2 NUP214 RNF157 ASAP1 PHLDB1 PXDN BAZ2A TLN1

1.15e-04407159912693553
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

GGA2 NCOR1 TLN1 ZFHX2 SORCS3

1.20e-04104159510470851
Pubmed

Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking.

MYLK KALRN

1.24e-044159219706030
Pubmed

Targeting skeletal endothelium to ameliorate bone loss.

HIVEP3 SLIT3

1.24e-044159229785024
Pubmed

GATA6, SF1, NGFIB and DAX1 in the remodeled subcapsular zones in primary aldosteronism.

NR4A1 NR5A1

1.24e-044159224531914
Pubmed

Characterization of a new ARID family transcription factor (Brightlike/ARID3C) that co-activates Bright/ARID3A-mediated immunoglobulin gene transcription.

ARID3A ARID3B

1.24e-044159221955986
Pubmed

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.

NRG1 DGKH EYS TPD52

1.28e-0456159423934736
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 DIP2B SHROOM3 SORBS2 TRIO NUMBL KALRN TRIOBP ARHGAP39 SIK3 BCL9 NCOR1 ATF7IP LAMTOR1

1.46e-049631591428671696
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

FBRSL1 ARID3B NCOR1

1.77e-0424159333722704
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

WHRN DIP2B MMS22L COPG1 SEC24A DCDC2B SIK3 ADAR NACAD ESCO1 RNF157 NUTM2G CFHR4 BRDT SUPV3L1 NUTM2F

1.94e-0412421591630973865
Pubmed

Assembly of high order G alpha q-effector complexes with RGS proteins.

TRIO KALRN

2.06e-045159218936096
Pubmed

Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex.

NR4A1 NR5A1

2.06e-045159216002533
Pubmed

Aberrant epithelial polarity cues drive the development of precancerous airway lesions.

NRG1 FOXJ1

2.06e-045159233903236
Pubmed

Involvement of Nurr-1/Nur77 in corticotropin-releasing factor/urocortin1-induced tyrosinase-related protein 1 gene transcription in human melanoma HMV-II cells.

NR4A1 CRH

2.06e-045159223416839
Pubmed

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.

NRG1 LAMA4 NR5A1

2.26e-0426159328684471
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

HIVEP1 NELFA BCL9 ARID3B PRR12 NCOR1 RPRD2

2.46e-04268159733640491
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

EPN3 SHROOM3 NUMBL PPP1R13B NUP214 ASAP1 KIAA1671 TLN1 SNX9 TPD52

2.91e-045651591025468996
Pubmed

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases.

INPP5D KLRD1

3.08e-04615929485206
Pubmed

The dorsal aorta initiates a molecular cascade that instructs sympatho-adrenal specification.

NRG1 NR5A1

3.08e-046159222723422
Pubmed

Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia.

INPP5D CSF3R

3.08e-046159215470047
Pubmed

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription.

TAF1C CCNA2

3.08e-046159211698641
Pubmed

Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth.

NRG1 JAK2

3.08e-046159219103753
Pubmed

Functional proteomics mapping of a human signaling pathway.

EPN3 SOX5 HIVEP1 MAN2B1 MAN1C1 LAMA4 PPP1R13B ZZEF1 NCOR1 ATF7IP

4.14e-045911591015231748
Pubmed

The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis.

STMN2 CCNA2

4.30e-047159224676280
Pubmed

Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function.

NR4A1 NR5A1

4.30e-047159214726490
Pubmed

Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.

SOX5 HNF1B NR4A1 BAZ2A

4.39e-0477159421525287
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SOX5 SP2 KLF11 HIVEP1 ARID3A ZC3H8 NR4A1 OLIG3 BAZ2A PROX2 ZFHX2

4.44e-047091591122988430
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SP2 COL27A1 ARHGAP39 POM121C ESCO1 HIVEP3 PRR12 NUP210 HECTD1

4.69e-04493159915368895
Pubmed

Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase.

DTL CCNA2

5.71e-048159229424068
Pubmed

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.

KLF11 HOXD1

5.71e-048159222930747
Pubmed

Numb regulates somatic cell lineage commitment during early gonadogenesis in mice.

NUMBL NR5A1

5.71e-048159228360133
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SHROOM3 GGA2 TRIO SEC24A PPP1R13B SIK3 ASAP1 KIAA1671 NCOR1 CEP20 TLN1 SNX9

5.84e-048531591228718761
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

COPG1 PCLO DGKH ZZEF1 ESCO1 ERLEC1 KIAA1671 JAK2 TLN1 LONRF2 RBM43

6.04e-047361591129676528
Pubmed

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.

LAMA4 CRH RNF157 MED25

6.67e-0486159419501082
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

COL27A1 PPP1R13B NUP214 ADAR ESCO1

6.91e-04152159534299191
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP214 POM121C NUP210

7.03e-0438159312791264
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

HIVEP1 NUP214 KIAA1671 PRR12 NCOR1 ATF7IP SKA3 MRTFA

7.13e-04418159834709266
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

ARID3A MAN2B1 NUMBL SEC24A SPATA32 SUPV3L1 NUP210 SKA3

7.24e-04419159833001583
Pubmed

Superresolution imaging of chemical synapses in the brain.

SHANK1 PCLO

7.32e-049159221144999
Pubmed

Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells.

STMN2 NR5A1

7.32e-049159216176945
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

WHRN HIVEP1 KALRN NACAD SIRT4 NCOR1

7.38e-04233159637704626
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

HIVEP1 FBRSL1 SIK3 SMOC2 BCL9 POM121C ARID3B NCOR1 PHLDB1 ACSS3

7.46e-046381591031182584
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

GGA2 NUMBL NELFA SEC24A NUP214 BCL9 POM121C ERLEC1 CCNA2 KIAA1671 NUP210 LAMTOR1 PSRC1

7.69e-0410071591334597346
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BICRA PCLO BCL9 NPM3 PRR12 NCOR1 ATF7IP NUP210

7.94e-04425159824999758
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP214 ADAR NUP210

8.18e-0440159337516964
Pubmed

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.

NR4A1 HIVEP3 DMRTA2

8.80e-0441159322147266
Pubmed

A protein interaction network for pluripotency of embryonic stem cells.

ARID3A SALL4 ARID3B

8.80e-0441159317093407
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

PCLO FBRSL1 AUTS2

8.80e-0441159322325352
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DIP2B SORBS2 HIVEP1 NELFA NUP214 ARHGAP39 BCL9 NCOR1 BAZ2A FIP1L1 MRTFA

9.10e-047741591115302935
InteractionHNF1B interactions

SOX5 HNF1B HIVEP1 ARID3A BICRA BCL9 ARID3B PRR12 NCOR1 ATF7IP

1.96e-0619015310int:HNF1B
InteractionTBR1 interactions

SOX5 HNF1B HIVEP1 FBRSL1 BCL9 PRR12 NCOR1 BRDT

2.40e-061131538int:TBR1
InteractionNFIB interactions

SOX5 HNF1B HIVEP1 ARID3A BCL9 ARID3B PRR12 NCOR1

1.31e-051421538int:NFIB
InteractionSP7 interactions

SOX5 HNF1B HIVEP1 ARID3A BICRA FBRSL1 BCL9 ARID3B PRR12 NCOR1 RPRD2

2.15e-0530415311int:SP7
InteractionFEV interactions

SOX5 SP2 HIVEP1 ARID3A BICRA FBRSL1 BCL9 PRR12 NCOR1

2.55e-052031539int:FEV
InteractionAGAP2 interactions

SHANK1 SORBS2 TRIO NUMBL KALRN PCLO ARHGAP39 SIK3 ASAP1

3.33e-052101539int:AGAP2
InteractionPAX7 interactions

HNF1B HIVEP1 ARID3A FBRSL1 BCL9 PRR12 NCOR1

4.54e-051241537int:PAX7
InteractionPAX2 interactions

HNF1B HIVEP1 FBRSL1 BBS4 BCL9 PRR12

4.63e-05851536int:PAX2
InteractionEGR2 interactions

SOX5 HIVEP1 ARID3A BICRA FBRSL1 BCL9 PRR12 NCOR1

4.97e-051711538int:EGR2
InteractionGSC interactions

SOX5 HIVEP1 SPPL3 BCL9 PRR12 AUTS2

5.28e-05871536int:GSC
InteractionERG interactions

HIVEP1 ARID3A BICRA FBRSL1 BCL9 ADAR PRR12 NCOR1 ATF7IP

5.32e-052231539int:ERG
InteractionTLX1 interactions

HIVEP1 ARID3A FBRSL1 BCL9 ARID3B PRR12 NCOR1 AUTS2

5.85e-051751538int:TLX1
InteractionVASP interactions

DIP2B SHROOM3 NUMBL SEC24A PPP1R13B NR4A1 KIAA1671 MICALL2 NBR1 MRTFA

8.58e-0529415310int:VASP
InteractionSOX17 interactions

HNF1B ARID3A BCL9 ARID3B PRR12 NCOR1

8.65e-05951536int:SOX17
InteractionNFIA interactions

SOX5 HNF1B HIVEP1 ARID3A BCL9 ARID3B PRR12 NCOR1

9.66e-051881538int:NFIA
InteractionSOX9 interactions

HNF1B ARID3A BCL9 ARID3B PRR12 NR5A1

9.71e-05971536int:SOX9
GeneFamilyAT-rich interaction domain containing

ARID3A ARID5A ARID3B

7.55e-05151023418
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZSWIM2 ZZEF1 NBR1

1.34e-0418102391
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

SOX5 SORBS2 MYLK KALRN DGKH SIK3 NR4A1 SLIT3 AUTS2

4.20e-071551579M39246
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP

ARID3A INPP5D DTL LAMA4 SMOC2 BCL9 SLIT3 IGSF1

6.27e-061621578M45037
CoexpressionTSANG_PBMC_FLUVIRIN_PANDEMRIX_ADULT_CORR_WITH_CELL_FREQ_CD27HI_CD38HI_CD20_NEG_PLASMABLASTS_AND_CD38PLUS_OF_IGD_CD27PLUS_MEM_B_CELLS_7DY_POSITIVE

SEC24A DTL MEI1 ERLEC1 CCNA2 TPD52

7.55e-06781576M41196
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

DIP2B NRG1 SORBS2 RNF152 COL27A1 SPPL3 KIAA1671 NCOR1 BAZ2A SLIT3 CFAP46 TPD52

8.58e-0641715712M39224
CoexpressionGSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP

WHRN MAGEA5P NRG1 MAMLD1 RGS20 MICALL2 SLIT3 KLRD1

2.50e-051961578M7687
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL

CDHR3 PCLO STMN2 NACAD CRH HIVEP3 PTPRN SETBP1 LONRF2

3.62e-052681579M45696
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN KALRN DTL LAMA4 NR4A1 SMOC2 MEI1 PROX2 PSRC1

8.13e-0916316091e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN KALRN DTL LAMA4 NR4A1 SMOC2 MEI1 PROX2 PSRC1

8.13e-091631609431221a41d396b09170476179590eaf8a55266d8
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VEGFC MYLK COL27A1 MAMLD1 LAMA4 HIVEP3 SETBP1 SLIT3 TMEM108

3.52e-081931609b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

VEGFC MYLK KALRN COL27A1 LAMA4 SETBP1 SLIT3 AUTS2 TMEM108

4.20e-081971609f1c8936986123a3151140c374fcd62d6705c530b
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

VEGFC LAMA4 NR4A1 SMOC2 CRH RGS20 SLIT3 TMEM108

5.07e-071931608cf2461af78f65616ce40d552ee9452295e3895ed
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

VEGFC MYLK MAMLD1 LAMA4 HIVEP3 SETBP1 SLIT3 TMEM108

5.07e-07193160899525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

VEGFC LAMA4 NR4A1 SMOC2 CRH RGS20 SLIT3 TMEM108

5.07e-0719316086ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

VEGFC LAMA4 NR4A1 SMOC2 CRH RGS20 SLIT3 TMEM108

5.07e-071931608e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NRG1 PCLO STMN2 SMOC2 CRH PTPRN LONRF2 TPD52

5.27e-071941608b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

TARM1 MYLK COL27A1 LAMA4 POM121L2 SALL4 SLIT3

1.79e-0615916073f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

TARM1 MYLK COL27A1 LAMA4 POM121L2 SALL4 SLIT3

2.20e-0616416072ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL27A1 MAMLD1 SMOC2 ASAP1 P2RY11 SLIT3

2.90e-061711607972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL27A1 MAMLD1 SMOC2 ASAP1 P2RY11 SLIT3

2.90e-0617116072a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

RNF152 MYLK KALRN NR4A1 PXDN SETBP1 SLIT3

3.01e-061721607c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX5 RNF152 KALRN COL27A1 NR4A1 SMOC2 SLIT3

3.38e-0617516071125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

SOX5 RNF152 MYLK COL27A1 SMOC2 SETBP1 SLIT3

3.92e-061791607a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

SOX5 RNF152 MYLK KALRN SMOC2 SETBP1 SLIT3

5.23e-061871607464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

VEGFC MYLK COL27A1 LAMA4 SETBP1 SLIT3 TMEM108

5.23e-061871607e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

SOX5 SORBS2 RNF152 MYLK KALRN SMOC2 SLIT3

5.41e-061881607b66264e8f8d536ed2beec31e6746c687718f239b
ToppCellNS-moderate-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX5 GGA2 ARID3A INPP5D SGPP1 SETBP1 NUP210

5.41e-061881607e9ed34cfea1d93eaa8e63d5b5dbb64f1520d9c4c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRG1 COL27A1 STMN2 LAMA4 SALL4 PHLDB1 PXDN

5.41e-061881607997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|368C / Donor, Lineage, Cell class and subclass (all cells)

INPP5D MEI1 ZZEF1 ARID3B TBCCD1 PRR12 NUP210

5.60e-061891607610d7cc1fc923dbd67d3b71f94d529a658982f87
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

SOX5 ZC3H8 INPP5D SGPP1 SETBP1 NUP210 TPD52

5.80e-061901607374d8fd63c733178acab07682ed1519693efab45
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NRG1 STMN2 SMOC2 CRH PTPRN LONRF2 TPD52

5.80e-0619016072375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HNF1B SORBS2 LEMD1 KIAA1671 PIK3C2G NUP210 TPD52

5.80e-061901607625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 HNF1B PPP1R13B NR4A1 PIK3C2G AUTS2 ACSS3

6.00e-06191160734cc997e4e5c727495f321e6807a84aa124da486
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KALRN MAN1C1 MAMLD1 LAMA4 ASAP1 HIVEP3 TMEM108

6.00e-06191160708720998aa55131d7377c4c67c4c935865bd7d79
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 SHROOM3 SORBS2 PPP1R13B CSF3R AUTS2 ACSS3

6.00e-061911607a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 HNF1B MYLK TRIO CDHR3 COL27A1 DGKH

6.00e-0619116071cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HNF1B SORBS2 LEMD1 PIK3C2G NUP210 TPD52 FOXJ1

6.21e-061921607b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NRG1 PCLO STMN2 SMOC2 CRH PTPRN TPD52

6.43e-0619316078603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYLK MAMLD1 LAMA4 HIVEP3 SETBP1 SLIT3 TMEM108

6.65e-061941607e93de9428c986b8943fc169258847c650cfab0e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYLK LAMA4 SALL4 SMOC2 ASAP1 SLIT3

6.65e-06194160790efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYLK LAMA4 SALL4 SMOC2 ASAP1 SLIT3

6.65e-061941607df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 KALRN LAMA4 SMOC2 MICALL2 SETBP1 SLIT3

7.35e-061971607ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 KALRN LAMA4 SMOC2 MICALL2 SETBP1 SLIT3

7.35e-06197160737f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

NRG1 SORBS2 MYLK SALL4 ARID5A SLIT3 CFAP46

7.85e-061991607bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RNF152 MYLK KALRN LAMA4 PXDN SETBP1 SLIT3

7.85e-061991607b1753474152b82a0b811b9878c890a359e14919a
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHROOM3 CDHR3 MEIKIN KIAA1671 RGS20 MICALL2 ACSS3

8.11e-062001607d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHROOM3 CDHR3 MEIKIN KIAA1671 RGS20 MICALL2 ACSS3

8.11e-062001607f861509b54185d89931db64da1b9d81986cc7938
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHROOM3 CDHR3 MEIKIN KIAA1671 RGS20 MICALL2 ACSS3

8.11e-06200160716f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHROOM3 CDHR3 MEIKIN KIAA1671 RGS20 MICALL2 ACSS3

8.11e-0620016070442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHROOM3 CDHR3 MEIKIN KIAA1671 RGS20 MICALL2 ACSS3

8.11e-06200160701819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMS22L BCL9 CCNA2 JAK2 CEP20 SUPV3L1

1.26e-0514216065690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 SHROOM3 RNF152 MAN1C1 C4orf54 PIK3C2G

2.31e-051581606debebc8534a80e5500051f6fd352dc201585968d
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

RNF152 MYLK KALRN DGKH SMOC2 SLIT3

2.48e-05160160629c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

RNF152 MYLK KALRN DGKH SMOC2 SLIT3

2.57e-05161160647b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TARM1 MMS22L INPP5D ARHGAP39 SGPP1 JAK2

2.76e-0516316067af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

WHRN HIVEP1 NR4A1 ARID5A AGAP3 FOXJ1

3.27e-051681606ea465152ea31391b63c02425beafa9a4f51f6703
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC NRG1 STMN2 DGKH PHLDB1 SLIT3

3.49e-05170160650c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC NRG1 STMN2 DGKH PHLDB1 SLIT3

3.49e-0517016068fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC NRG1 STMN2 DGKH PHLDB1 SLIT3

3.49e-0517016063232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

SOX5 MYLK KALRN DGKH SMOC2 SLIT3

3.61e-051711606e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM3 MYLK CDHR3 DGKH CCDC168 PIK3C2G

3.85e-0517316068ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 SORBS2 MYLK DGKH CCDC168 PIK3C2G

3.98e-051741606b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 SHROOM3 MYLK DGKH CCDC168 PIK3C2G

3.98e-051741606ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDHR3 PCLO STMN2 ZP2 EYS PTPRN

3.98e-0517416069f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VEGFC NRG1 SORBS2 RNF152 LAMA4 MEI1

4.37e-05177160664fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX5 ARID3A INPP5D NR4A1 SGPP1 SETBP1

4.37e-051771606320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM3 PCLO CRH CELA3A PTPRN TIGD3

4.37e-051771606c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL27A1 HIVEP3 SLIT3 SORCS3 TMEM108 ACSS3

4.80e-05180160608ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 HNF1B RNF152 CDHR3 COL27A1 PCLO

4.80e-051801606358923e4228035a3e90e2957392089219e90dcd7
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

VEGFC MYLK LAMA4 SETBP1 SLIT3 TMEM108

4.95e-0518116069ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LAMA4 ZSWIM2 ASAP1 HIVEP3 AUTS2

5.11e-05182160641b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LAMA4 ZSWIM2 ASAP1 HIVEP3 AUTS2

5.11e-0518216065e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LAMA4 ZSWIM2 ASAP1 HIVEP3 AUTS2

5.11e-051821606b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF152 MAN1C1 SMOC2 CRH PTPRN DMRTA2

5.11e-0518216061923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF152 MAN1C1 SMOC2 CRH PTPRN DMRTA2

5.11e-05182160669ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

SOX5 RNF152 MYLK PHLDB1 PXDN SLIT3

5.43e-051841606a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INPP5D DTL MEI1 CCNA2 NUP210 SKA3

5.43e-0518416068260e688ec42a1374727bc85dceb7edd19a8b662
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 LAMA4 SMOC2 SETBP1 SLIT3 AUTS2

5.59e-051851606a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PCLO STMN2 SMOC2 CRH PTPRN NUP210

5.59e-051851606f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SOX5 GGA2 ARID3A INPP5D SGPP1 SETBP1

5.76e-051861606fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARID3A MAMLD1 SMOC2 MEI1 ARID5A CSF3R

5.93e-051871606fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

VEGFC MYLK LAMA4 SETBP1 SLIT3 TMEM108

5.93e-05187160692d468dde81125d51daf7abd4703741abe1ab91c
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DTL CCDC168 CCNA2 SKA3 KLRD1 PSRC1

6.11e-051881606319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HNF1B PCLO PPP1R13B SMOC2 LONRF2 TPD52

6.11e-0518816060d86044bc340e3efb90d0022dd299873639d831c
ToppCellnormal-na-Lymphocytic_B-B_atypical-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

SOX5 GGA2 SMOC2 SETBP1 TIGD3 TPD52

6.11e-051881606e5ab89030783461e9367ab87c353fb5c31911020
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SORBS2 LAMA4 SMOC2 ULBP3 SETBP1 ITIH6

6.11e-051881606c9270517e6940e9793586f67f02431210552f278
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

SORBS2 RNF152 MYLK KALRN SMOC2 SLIT3

6.11e-051881606e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MAMLD1 LAMA4 SMOC2 PXDN SLIT3

6.29e-05189160671397e993a77d70b2eeede240bdfc7660b558987
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VEGFC HIVEP1 KALRN COL27A1 HOXD1 SETBP1

6.29e-051891606bccb3481ffed597c845fe860da658505316105b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MAMLD1 LAMA4 SMOC2 PXDN SLIT3

6.29e-0518916064eea4759520c312bd17a681034d8074e47093d2b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 SORBS2 TRIO CDHR3 COL27A1 DGKH

6.29e-0518916063b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA4 SETBP1 SLIT3 SORCS3 TMEM108 ACSS3

6.29e-0518916062a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HNF1B PCLO SMOC2 NUP210 TPD52 FOXJ1

6.48e-051901606c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 RNF152 LAMA4 DGKH PHLDB1 SLIT3

6.48e-0519016064eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 RNF152 LAMA4 DGKH PHLDB1 SLIT3

6.48e-0519016067be4341e2909101d756f14031c21e705eb45e69a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK LAMA4 SETBP1 SLIT3 SORCS3 ACSS3

6.67e-051911606b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 KALRN LAMA4 PXDN SLIT3 AUTS2

6.67e-051911606107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 SHROOM3 SORBS2 PPP1R13B AUTS2 ACSS3

6.67e-051911606e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell11.5-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

PCLO CRH PTPRN TIGD3 LONRF2 TPD52

6.67e-051911606c1bb3ae5c297f55cdadf5b6e53d5296389d5099e
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

SOX5 RNF152 KALRN DGKH PXDN SLIT3

6.67e-051911606fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 KALRN LAMA4 PXDN SLIT3 AUTS2

6.67e-051911606bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VEGFC MYLK LAMA4 SETBP1 SLIT3 TMEM108

6.67e-0519116066688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HNF1B OLIG3 DMRTA2 ZNF541

6.86e-0561160446cdf693c7f2df4fc43df7837b152871af67bef0
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HNF1B OLIG3 DMRTA2 ZNF541

6.86e-05611604c73fa489427a6e11badbdfc0324008137806ac7d
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HNF1B OLIG3 DMRTA2 ZNF541

6.86e-05611604c2c633f49f6ad8581c33794c909f40aa59f0b5c5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL27A1 MAMLD1 LAMA4 PXDN SLIT3

6.87e-0519216069093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL27A1 MAMLD1 LAMA4 PXDN SLIT3

6.87e-0519216069ed5d49621ec1aa01716dc369bba1450b5f015f5
DrugEthisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A

MTHFSD GGA2 TAF1C POM121L2 NR4A1 ZZEF1 ARID5A JAK2 TLN1 MED25

7.01e-07190154104340_DN
DrugBenzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

WHRN MAN1C1 PCLO LAMA4 NR4A1 ZZEF1 HIVEP3 RGS20 MRTFA

6.61e-0619215493635_UP
Diseasebody weight

SOX5 NRG1 HNF1B MMS22L HIVEP1 COPG1 DTL POM121L2 DGKH ZZEF1 POM121C ERLEC1 NCOR1 EYS MICALL2 PTPRN SETBP1 SLIT3 AUTS2 ITIH6 NUTM2F

1.96e-06126115121EFO_0004338
Diseaseunipolar depression, bipolar disorder

VEGFC SOX5 PCLO SPPL3 SETBP1 SORCS3 RPRD2

1.65e-051561517EFO_0003761, MONDO_0004985
DiseaseLeukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

CSF3R SETBP1

7.78e-0531512C1292772
Diseasesevere acute respiratory syndrome, COVID-19

SOX5 INPP5D MAMLD1 SMOC2 EYS AMMECR1L PXDN PIK3C2G NUP210 AUTS2

1.08e-0444715110EFO_0000694, MONDO_0100096
Diseaseserum gamma-glutamyl transferase measurement

HNF1B SORBS2 KALRN BICRA SPPL3 TRIOBP ZC3H11B POM121C EYS TLN1 DMRTA2 SNX9 PSRC1 ACSS3

2.65e-0491415114EFO_0004532
DiseaseLeukemia, Myelocytic, Acute

TRIO NUP214 JAK2 PXDN CSF3R SETBP1

2.75e-041731516C0023467
Diseaseresponse to perphenazine

SOX5 C4orf54 PXDN

3.13e-04261513GO_0097334
Diseasestimulant use measurement

HIVEP1 ASAP1 EYS

3.92e-04281513EFO_0600076
DiseaseMyeloid Leukemia, Chronic

JAK2 CSF3R SETBP1

4.35e-04291513C0023473
Diseaseserum alanine aminotransferase measurement

WHRN DIP2B HNF1B SHROOM3 COL27A1 PCLO ZC3H11B ARHGAP39 POM121C PARP6 SUPV3L1 NUP210 PSRC1

5.49e-0486915113EFO_0004735
Diseaseblood urea nitrogen measurement

NRG1 HNF1B SHROOM3 DGKH LEMD1 PHLDB1 HOXD1 MICALL2 SETBP1

5.57e-044521519EFO_0004741
Diseasediastolic blood pressure, self reported educational attainment

PIK3C2G SLIT3

7.14e-0481512EFO_0004784, EFO_0006336
Diseaseresponse to selective serotonin reuptake inhibitor

NRG1 BICRA STMN2 AUTS2

8.46e-04821514EFO_0005658
Diseaseinfection

INPP5D ZNF541

9.15e-0491512EFO_0000544
Diseaseserum albumin measurement

VEGFC HNF1B SHROOM3 HIVEP1 MAMLD1 ZC3H11B SIK3 ZZEF1 ADAR PRR12

9.82e-0459215110EFO_0004535
Diseasecholelithiasis

HNF1B SHROOM3 ADAR SNX9

1.10e-03881514EFO_0004799
Diseaseresponse to anticoagulant

CDHR3 SMOC2 BCL9

1.21e-03411513GO_0061476
DiseaseIschemic stroke, coronary artery disease

SOX5 SORBS2 NPM3 NLRP5

1.30e-03921514EFO_0001645, HP_0002140
Diseasecoagulation factor XA measurement

WHRN COL27A1

1.39e-03111512EFO_0020266
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

WHRN DIP2B HNF1B ARHGAP39 SUPV3L1 AUTS2

1.49e-032391516EFO_0010934
DiseaseMajor Depressive Disorder

KALRN PCLO NR4A1 BCL9 CRH SLIT3

1.62e-032431516C1269683
Diseasehearing impairment

WHRN SLC29A3 TRIOBP SALL4

1.64e-03981514C1384666
DiseaseMyoinositol measurement

FBRSL1 ZP2

1.66e-03121512EFO_0021652
Diseasechronic kidney disease (implicated_via_orthology)

SHROOM3 NR4A1

1.66e-03121512DOID:784 (implicated_via_orthology)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP1 HIVEP3

1.96e-03131512DOID:0050787 (implicated_via_orthology)
DiseasePain, Migratory

NRG1 CRH HOXD1

2.04e-03491513C0751407
DiseaseSuffering, Physical

NRG1 CRH HOXD1

2.04e-03491513C0751408
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

DIP2B FBRSL1 ZC3H11B

2.04e-03491513EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
DiseasePain, Crushing

NRG1 CRH HOXD1

2.04e-03491513C0458259
DiseasePain, Splitting

NRG1 CRH HOXD1

2.04e-03491513C0458257
DiseasePain

NRG1 CRH HOXD1

2.04e-03491513C0030193
DiseaseRadiating pain

NRG1 CRH HOXD1

2.04e-03491513C0234254
DiseasePain, Burning

NRG1 CRH HOXD1

2.04e-03491513C0234230
DiseaseAche

NRG1 CRH HOXD1

2.04e-03491513C0234238
Diseasepulse pressure measurement

DIP2B NRG1 SHROOM3 COL27A1 FBRSL1 TRIOBP ZC3H11B SMOC2 MEI1 ERLEC1 ARID5A CCNA2 HIVEP3 SLIT3 SORCS3 DMRTA2

2.12e-03139215116EFO_0005763
Diseasehematocrit

VEGFC SOX5 NRG1 HNF1B SHROOM3 HIVEP1 NUMBL KALRN MAMLD1 FBRSL1 PPP1R13B PRR12 MICALL2

2.14e-03101115113EFO_0004348
DiseaseUnipolar Depression

KALRN PCLO DGKH BCL9 CRH SLIT3

2.23e-032591516C0041696
Diseaseage at last pregnancy measurement

SORCS3 LONRF2

2.27e-03141512EFO_0009440
DiseaseMaturity onset diabetes mellitus in young

KLF11 HNF1B

2.27e-03141512C0342276
Diseasegallstones

HNF1B SHROOM3 ADAR SNX9

2.34e-031081514EFO_0004210
Diseasecognitive function measurement, self reported educational attainment

MMS22L TRIOBP PRR12 AUTS2 SORCS3 LONRF2 MRTFA

2.42e-033551517EFO_0004784, EFO_0008354
Diseaseserum selenium measurement

NRG1 INPP5D MED25

2.55e-03531513EFO_0005266
Diseaseneuroticism measurement

SOX5 KLF11 MMS22L HIVEP1 ZC3H8 INPP5D PCLO POM121L2 CSF3R PROX2 SORCS3 ACSS3

2.56e-0390915112EFO_0007660
Diseasearm span

CDHR3 AUTS2

2.61e-03151512EFO_0005108
DiseaseAlopecia, Male Pattern

CRH SUPV3L1

2.61e-03151512C4083212
Diseaseacute graft vs. host disease, donor genotype effect measurement

KALRN EYS

2.61e-03151512EFO_0004599, EFO_0007892
DiseaseAndrogenetic Alopecia

CRH SUPV3L1

2.61e-03151512C0162311
DiseaseFemale pattern alopecia (disorder)

CRH SUPV3L1

2.61e-03151512C0263477
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

MMS22L HIVEP1 ZZEF1 POM121C HIVEP3 SETBP1 AUTS2

2.78e-033641517EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseprostate specific antigen measurement

SHANK1 MTHFSD HNF1B ZC3H11B ATF7IP

2.88e-031881515EFO_0004624
DiseaseMonogenic diabetes

KLF11 HNF1B

2.98e-03161512C3888631
Diseaseneuroblastoma

TRIO KALRN SALL4 NPM3

3.03e-031161514EFO_0000621
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX5 HIVEP1 HIVEP3

3.14e-03571513DOID:10652 (implicated_via_orthology)
DiseaseAcute myeloid leukemia

NUP214 JAK2

3.36e-03171512cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

NUP214 JAK2

3.36e-03171512601626
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

DIP2B TRIO

3.36e-03171512DOID:0060307 (is_implicated_in)
Diseaseage at first birth measurement

CELA3A SORCS3 IGSF1 LONRF2

3.42e-031201514EFO_0009101
Diseasepain

SOX5 POM121L2 SORCS3 RPRD2 PSRC1

3.44e-031961515EFO_0003843
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

SOX5 PCLO SPPL3 PPP1R13B SORCS3

3.75e-032001515EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseasebody fat percentage

MMS22L HIVEP1 ZC3H11B ZZEF1 POM121C HIVEP3 SETBP1 AUTS2

3.75e-034881518EFO_0007800
DiseaseAcute Myeloid Leukemia, M1

TRIO NUP214 JAK2 PXDN

3.96e-031251514C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

TRIO NUP214 JAK2 PXDN

3.96e-031251514C1879321
Diseaseosteoarthritis, hip, osteoarthritis, knee

SOX5 COL27A1 ZC3H11B

3.98e-03621513EFO_0004616, EFO_1000786
Diseaseparental longevity

SHROOM3 BICRA PCLO FBRSL1 POM121C PROX2 SETBP1 PSRC1

4.04e-034941518EFO_0007796
DiseasePseudopelade

CRH SUPV3L1

4.20e-03191512C0086873
DiseaseAlopecia

CRH SUPV3L1

4.20e-03191512C0002170
Diseasecaffeine metabolite measurement

NUMBL ARID3B

4.20e-03191512EFO_0007872
Diseasehemifacial microsomia

SHROOM3 ARID3B

4.20e-03191512MONDO_0015398
DiseaseTinnitus

FBRSL1 SPATA31A1 FIP1L1 SORCS3

4.55e-031301514HP_0000360
Diseasevital capacity

DIP2B NRG1 MMS22L SHROOM3 PCLO ZSWIM2 POM121L2 ZZEF1 NCOR1 OLIG3 VRTN AUTS2 RPRD2 AGAP3

4.56e-03123615114EFO_0004312
Diseaserenal system measurement

SHROOM3 MICALL2

4.65e-03201512EFO_0004742
Diseasemagnesium measurement

SHROOM3 CCDC168 ASAP1

4.75e-03661513EFO_0004845
Diseasealcohol consumption measurement

SOX5 MMS22L PCLO FBRSL1 PPP1R13B ZC3H11B ZSWIM2 BRDT SETBP1 AUTS2 DMRTA2 RPRD2 NR5A1 ACSS3

4.75e-03124215114EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
KLFLAPLPSSDVPLG

AGAP3

736

Q96P47
AAAAGAPALLSPPKI

ARID3B

346

Q8IVW6
CQSLPGSPFKPLTLR

ERLEC1

261

Q96DZ1
PAPLSASILSQKPGR

FBRSL1

576

Q9HCM7
GGTSQFTKPPSLPLE

BBS4

486

Q96RK4
GPLKGQAALPFSPLV

ARID5A

516

Q03989
LSPLPRPNGTANTTK

AMMECR1L

86

Q6DCA0
KNISPLQILPPSGDS

BRDT

751

Q58F21
PVQFSSTPLAGLAPK

BAZ2A

1371

Q9UIF9
KTRNPFLTGLSAPSP

EPN3

521

Q9H201
LQLKAAPASSNPPGA

ANKRD13C

61

Q8N6S4
PIPSSQLALPFLGLS

CFAP46

2626

Q8IYW2
GDLPLPSNTPTFSIK

DTL

456

Q9NZJ0
FLKGPSLQPSDPSLG

CEP20

126

Q96NB1
FPKTLLQAGRPGSPL

DMRTA2

196

Q96SC8
GSFPVLGDPIKPQSL

PPP1R13B

356

Q96KQ4
ATLLGKAGAFPPPAI

NUMBL

531

Q9Y6R0
IPSLSFSPLKPNGRI

RBM43

136

Q6ZSC3
SPLLAQPRKPSGDSQ

ARHGAP39

286

Q9C0H5
NPPFIKLSDPGISIT

JAK2

691

O60674
VSKAPAIGFSPSVLP

PIK3C2G

101

O75747
AIGFSPSVLPKPQNT

PIK3C2G

106

O75747
SAAGSQSPALPPRLK

NRG1

26

Q02297
KIPESTPLGSRFPLQ

PCDHB1

141

Q9Y5F3
LEKLGFSPGPILPST

LEMD1

16

Q68G75
TGPSPSLAQSPLKLF

NR4A1

196

P22736
ALSVGNKPSLTNPFP

NUP210

721

Q8TEM1
SVGPLPKAEAPALFS

PTPRN

231

Q16849
GQALPLNATAAPKPS

P2RY11

351

Q96G91
APSKPTAPIFLQGLS

MYLK

616

Q15746
PLKSPQGASAIPTAI

MAGEA5P

61

P43359
KNNLPPLTGSVPDFS

EYS

1771

Q5T1H1
TQKPAGTLPRSAPLS

KIAA1671

186

Q9BY89
KNALTTLAGPLTPPV

NELFA

146

Q9H3P2
LQPPVTFRLKSGSGP

NPM3

116

O75607
PLQLPLSGTTPTKFI

HOXD1

301

Q9GZZ0
KGSSPPPRLASILAF

MMS22L

1081

Q6ZRQ5
ASASPKLTGLVPRQP

MICALL2

246

Q8IY33
KLPGLANTTLSTPNP

ISM2

111

Q6H9L7
PISPLSPGKALESAF

PCLO

3626

Q9Y6V0
ALALPSPALKALSGP

FAM205A

396

Q6ZU69
ALALPSPALKALSGP

FAM205BP

126

Q63HN1
PSLFKTGLPPSRNST

FIP1L1

261

Q6UN15
LPPLKISTSNGSPGF

KALRN

2286

O60229
GLLNKTPPTAALSAP

AUTS2

1206

Q8WXX7
LALVPANTLPKTPLG

DIP2B

896

Q9P265
GSLINSLKPSGPTPA

NUP214

1166

P35658
LASLTLPTKAFDAPP

LRRC14B

241

A6NHZ5
RLNLTPTPDLGSPAK

MEIKIN

16

A0A087WXM9
KAGLGPRFSPITPLQ

MED25

296

Q71SY5
LQPASSSKLPAFSPL

GGA2

546

Q9UJY4
STGPTCSILPKNPLF

NLRP5

26

P59047
LPTAPSAGLKRQFPD

LONRF2

391

Q1L5Z9
PQGAAAKSSSQLPIP

PSRC1

266

Q6PGN9
VPPGLPFSLTSSLKN

PCDHGC3

391

Q9UN70
LGNLNKSPAAPLSPA

CRH

76

P06850
PGPAVAASKENLPVL

DGKH

701

Q86XP1
SPKPLSTTPRGQSFL

RBM12B-AS1

21

Q9P1G2
LKAPSTPPALQLGSG

OLIG3

216

Q7RTU3
VALVPSGAQPLPATK

MEI1

1076

Q5TIA1
KTPSLLPPLGLSQSG

POM121C

606

A8CG34
KPSFLPSGAPASLEI

PROX2

211

Q3B8N5
LVLKNPSGSGPPLSI

HECTD1

2391

Q9ULT8
TLLAQPGPVVFPGKS

IGSF1

876

Q8N6C5
LGPPSFQNLLSPSEK

C2orf83

56

Q53S99
PEAQPKTLPLTGSTF

ADAR

826

P55265
QPRSKLPTLSFPSGV

DCDC2B

271

A2VCK2
NSFAPADIPVKGPLL

DBF4B

481

Q8NFT6
VKLSASLSPVIPGFP

CDHR3

46

Q6ZTQ4
LASLPPAGDILPNKT

CELA3A

141

P09093
LAGPAAAASIKSPPV

BCL9

896

O00512
EFSILNAKAPALPPG

FOXJ1

41

Q92949
SPQDKLALPGFSTPR

ASAP1

746

Q9ULH1
GPAQTPLLPAKLSAS

COL27A1

316

Q8IZC6
DAFQLPGLGTPPITK

CSF3R

681

Q99062
PPPISNGDTTSFLLK

CFHR4

461

Q92496
SGLTKNPVSLPSLPN

ATF7IP

826

Q6VMQ6
EKLSSPGLPQQSFTP

MAMLD1

461

Q13495
LLPAFNTPTGIPKGV

MAN1C1

291

Q9NR34
KPPTADLFTGVLPNG

MAN2B1

246

O00754
LLLDPSSPPTKALNG

LAMTOR1

21

Q6IAA8
ALTSQAPKGLPQSRP

ITIH6

796

Q6UXX5
AGNTKLLPLAPAPVF

KLF11

361

O14901
VSPKLGLLRTSFSPP

ESCO1

411

Q5FWF5
LGPLFKSSPEPVALT

COPG1

626

Q9Y678
LLGLPVGSTFPKPNV

CCDC168

6626

Q8NDH2
LAFNSAISLPGPRKP

CCNA2

126

P20248
LTPKPFAPAGATLTI

BICRA

366

Q9NZM4
GLPPLLPAENKAFAS

BICRA

1026

Q9NZM4
PTSLRLAAAPPQGLK

C4orf54

71

D6RIA3
IGQSPGLPSTTFKLP

RPRD2

611

Q5VT52
LSPGLAPFTLKPDGT

SALL4

306

Q9UJQ4
LLSPGAPLTKQSRSP

FAM126B

506

Q8IXS8
RAGLSIFSPIPKSPS

PARP6

171

Q2NL67
AAPAVAPLTPASLGK

PANX2

596

Q96RD6
GVPSNFKLPTSLNLP

LAMA4

986

Q16363
SPNFGVKLETLPLSP

HNF1B

36

P35680
AGPLVLSAFPSTPLV

NUTM2F

51

A1L443
AGPLVLSAFPSTPLV

NUTM2G

51

Q5VZR2
FKAGLQTSPPIVPLD

PEX16

131

Q9Y5Y5
VPGPNSKALPGFVLL

SLC29A3

371

Q9BZD2
FGSAIPIPSLPDKQV

SNX9

301

Q9Y5X1
PTKSRPDQPAAFGLL

NR5A1

251

Q13285
KLGPLSPTSFNPIIS

RNF157

331

Q96PX1
GVTKLPPGFSVSQLP

RNF152

56

Q8N8N0
PKSPLGRPESLLQSN

NBR1

341

Q14596
PKGFTAPPLRDSTLI

SPATA31A6

221

Q5VVP1
GLPTSAELFILPPKN

SORCS3

1051

Q9UPU3
PAAPKLFGLLSSPLS

RGS20

66

O76081
LQNSFIKSGPSVPPL

SEC24A

181

O95486
PSAPTPGLVLFQLSA

TAF1C

576

Q15572
TKAQLLGPISPPATR

PNPLA5

391

Q7Z6Z6
TGSILVSSPLKPNPL

NCOR1

911

O75376
PKGFTAPPLRDSTLI

SPATA31A7

221

Q8IWB4
PLAGPPITVTLFGKA

SGPP1

351

Q9BX95
LQPPATSPLLQGSKE

SPATA32

341

Q96LK8
SPKKFLPSTANRGLP

INPP5D

971

Q92835
GVGFSPTQALKVPPL

SIK3

911

Q9Y2K2
IPKAGALALPPNLTS

SHROOM3

1961

Q8TF72
KASIGLFVPASPPLD

SIRT4

26

Q9Y6E7
STSQGLSSFKPLPRP

WHRN

571

Q9P202
TSLFVPLTVKPQGPS

SUPV3L1

61

Q8IYB8
LKPSQAPTVPSSLGF

PRR12

191

Q9ULL5
QAILPAPPKSAGEAL

MRTFA

286

Q969V6
KNGTLTSFVPRPGPL

POM121L2

201

Q96KW2
DPGLSKLAFLVSPVP

SORBS2

691

O94875
STAKGPSLPELQFQP

TRIOBP

1691

Q9H2D6
LGSQEKSLPASPPAA

SHANK1

1426

Q9Y566
NIVVKLPLPPGAFSG

ACSS3

501

Q9H6R3
SLGTTALFPRKAQPP

ARID3A

166

Q99856
QDFKALPPQSLGVSP

SLIT3

1316

O75094
PKGFTAPPLRDSTLI

SPATA31A3

221

Q5VYP0
TNSPLVPTFCTPGLK

SKA3

281

Q8IX90
PGLAQPKAIATTLSP

ULBP3

216

Q9BZM4
PPGLTSQAQLPLSLK

TIGD3

151

Q6B0B8
PLSQGPKPVTISFAN

VEGFC

191

P49767
PPATATPASLPKFNL

ZFHX2

1931

Q9C0A1
PALSQKPSPLLGASG

TMEM52

171

Q8NDY8
PKGFTAPPLRDSTLI

SPATA31A1

221

Q5TZJ5
PKGFTAPPLRDSTLI

SPATA31A5

221

Q5VU36
LLAGLLPPVPAQKFS

SMOC2

11

Q9H3U7
TPKASAGPQPLLVQS

TLN1

941

Q9Y490
PRLSLPGKLVFPSST

SPPL3

246

Q8TCT6
PLPKIAPAGSIISLN

SP2

411

Q02086
LRTGLFNKITPPPGA

MTHFSD

91

Q2M296
VQRSGKPLLPFATGP

PXDN

941

Q92626
AELSPRPKQPLLSSG

HIVEP3

296

Q5T1R4
ALSQPTSIPGSPKFQ

PHLDB1

371

Q86UU1
DGLFLPPSKSVLPTV

ZC3H11B

91

A0A1B0GTU1
PTVSFGKIPSQTLLP

ZSWIM2

501

Q8NEG5
LGTQPKLPSSSGLPA

ZZEF1

1491

O43149
GQAFELILKPPSPIS

STMN2

51

Q93045
AGPLKASVPAALASP

SOX5

426

P35711
IVGALQVPPPSKFSL

TBCCD1

16

Q9NVR7
SPPGSPTLQKFGLLR

TPD52

36

P55327
KPAPALSAAGTPQLA

VRTN

451

Q9H8Y1
GQKPSLSPLVLEPAA

SETBP1

1486

Q9Y6X0
LTPPVASVKLGPFTL

ZP2

481

Q05996
SASNPNPLGLPTKVA

HIVEP1

1971

P15822
PLNSPLSSAVPSLGK

TRIO

2456

O75962
LKAGTPSPIQLQSPA

TARM1

161

B6A8C7
VSSQLPAPEGKPAAL

ZNF541

576

Q9H0D2
QAAPTILLTKPPGAT

TMEM108

136

Q6UXF1
LFSKPPNPALGKTAT

ZC3H8

6

Q8N5P1
TKLSIEPAFTPGPNI

KLRD1

36

Q13241
TPGPSHLALTFLPSK

NACAD

46

O15069