Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	BPTF MYH11 MLH1 ABCF2 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	3.07e-05	614	53	9	GO:0140657
GeneOntologyMolecularFunction	actin binding	MYH11 CALD1 HOOK1 MAP1A SPTA1 SYNE2 MICAL3 HCLS1	3.55e-05	479	53	8	GO:0003779
GeneOntologyMolecularFunction	cytoskeletal protein binding	S100A9 MYH11 ANK2 CALD1 HOOK1 MAP1A SPTA1 SYNE2 MICAL3 DYSF HCLS1	1.20e-04	1099	53	11	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	MLH1 ABCF2 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	1.57e-04	441	53	7	GO:0016887
GeneOntologyMolecularFunction	calmodulin binding	MYH11 ENKUR CALD1 NOS1 DDX5	3.55e-04	230	53	5	GO:0005516
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	MLH1 ABCF2 GCH1 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	9.37e-04	775	53	8	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	MLH1 ABCF2 GCH1 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	1.56e-03	839	53	8	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	MLH1 ABCF2 GCH1 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	1.57e-03	840	53	8	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MLH1 ABCF2 GCH1 OLA1 ATP1A4 HSPA6 NLRP3 DDX5	1.57e-03	840	53	8	GO:0016818
GeneOntologyMolecularFunction	cytoskeletal anchor activity	ANK2 MAP1A	1.84e-03	24	53	2	GO:0008093
GeneOntologyMolecularFunction	phosphatidic acid binding	MICALL1 RAPGEF2	1.84e-03	24	53	2	GO:0070300
GeneOntologyMolecularFunction	flavin adenine dinucleotide binding	DPYD MICAL3 NOS1	2.00e-03	94	53	3	GO:0050660
GeneOntologyMolecularFunction	calcium-dependent protein binding	S100A9 NOS1 DDX5	2.25e-03	98	53	3	GO:0048306
GeneOntologyMolecularFunction	ATPase binding	ANK2 NSFL1C NOS1	2.96e-03	108	53	3	GO:0051117
GeneOntologyBiologicalProcess	actin filament-based process	CFLAR S100A9 MYH11 ANK2 CALD1 SPTA1 SYNE2 IQSEC1 MICAL3 SPECC1L NOS1 HCLS1	2.59e-06	912	53	12	GO:0030029
GeneOntologyBiologicalProcess	microtubule-based process	LCA5 ENKUR NSFL1C HOOK1 MAP1A SYNE2 MLH1 SPECC1L ATP1A4 DYSF QRICH2 USP33	1.18e-05	1058	53	12	GO:0007017
GeneOntologyBiologicalProcess	protein depolymerization	MAP1A SPTA1 MICAL3 SPECC1L DYSF	3.39e-05	144	53	5	GO:0051261
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	MAP1A SPTA1 SPECC1L DYSF	8.07e-05	89	53	4	GO:1901880
GeneOntologyBiologicalProcess	plasma membrane organization	MICALL1 S100A9 ANK2 SPTA1 DYSF	1.20e-04	188	53	5	GO:0007009
GeneOntologyBiologicalProcess	negative regulation of microtubule depolymerization	MAP1A SPECC1L DYSF	1.27e-04	38	53	3	GO:0007026
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	MAP1A SPTA1 SPECC1L DYSF	1.27e-04	100	53	4	GO:0043242
GeneOntologyBiologicalProcess	supramolecular fiber organization	CFLAR MYH11 CALD1 HOOK1 MAP1A SPTA1 MICAL3 SPECC1L DYSF HCLS1	1.40e-04	957	53	10	GO:0097435
GeneOntologyBiologicalProcess	regulation of protein depolymerization	MAP1A SPTA1 SPECC1L DYSF	1.53e-04	105	53	4	GO:1901879
GeneOntologyBiologicalProcess	regulation of microtubule depolymerization	MAP1A SPECC1L DYSF	1.71e-04	42	53	3	GO:0031114
GeneOntologyBiologicalProcess	actin cytoskeleton organization	CFLAR S100A9 MYH11 CALD1 SPTA1 IQSEC1 MICAL3 SPECC1L HCLS1	1.87e-04	803	53	9	GO:0030036
GeneOntologyBiologicalProcess	T-tubule organization	ANK2 DYSF	2.31e-04	9	53	2	GO:0033292
GeneOntologyBiologicalProcess	negative regulation of microtubule polymerization or depolymerization	MAP1A SPECC1L DYSF	3.06e-04	51	53	3	GO:0031111
GeneOntologyCellularComponent	supramolecular fiber	MYH11 ENKUR ANK2 CALD1 HOOK1 MAP1A SYNE2 SPECC1L DYSF NOS1 HCLS1	1.50e-04	1179	53	11	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MYH11 ENKUR ANK2 CALD1 HOOK1 MAP1A SYNE2 SPECC1L DYSF NOS1 HCLS1	1.59e-04	1187	53	11	GO:0099081
GeneOntologyCellularComponent	microtubule organizing center	LCA5 NSFL1C HOOK1 SPECC1L OLA1 DYSF HSPA6 NLRP3 USP33	4.58e-04	919	53	9	GO:0005815
GeneOntologyCellularComponent	contractile muscle fiber	MYH11 ANK2 CALD1 SYNE2 NOS1	8.27e-04	290	53	5	GO:0043292
GeneOntologyCellularComponent	postsynapse	ANK2 CALD1 MAP1A PTPRO EIF4G1 IQSEC1 PPP1R2P1 RAPGEF2 NOS1	9.53e-04	1018	53	9	GO:0098794
GeneOntologyCellularComponent	T-tubule	ANK2 DYSF NOS1	1.06e-03	79	53	3	GO:0030315
Domain	CH	MICALL1 SYNE2 MICAL3 SPECC1L	2.73e-05	65	50	4	SM00033
Domain	CH	MICALL1 SYNE2 MICAL3 SPECC1L	3.66e-05	70	50	4	PF00307
Domain	-	MICALL1 SYNE2 MICAL3 SPECC1L	3.87e-05	71	50	4	1.10.418.10
Domain	CH	MICALL1 SYNE2 MICAL3 SPECC1L	4.32e-05	73	50	4	PS50021
Domain	CH-domain	MICALL1 SYNE2 MICAL3 SPECC1L	4.80e-05	75	50	4	IPR001715
Domain	DUF3585	MICALL1 MICAL3	1.46e-04	7	50	2	IPR022735
Domain	DUF3585	MICALL1 MICAL3	1.46e-04	7	50	2	PF12130
Domain	Spectrin	SPTA1 SYNE2	1.71e-03	23	50	2	PF00435
Domain	IQ_motif_EF-hand-BS	MYH11 ENKUR IQSEC1	1.80e-03	90	50	3	IPR000048
Domain	IQ	MYH11 ENKUR IQSEC1	1.98e-03	93	50	3	PS50096
Domain	-	CFLAR ANK2 NLRP3	1.98e-03	93	50	3	1.10.533.10
Domain	TUDOR	SETDB1 PHF20	2.36e-03	27	50	2	SM00333
Domain	DEATH-like_dom	CFLAR ANK2 NLRP3	2.36e-03	99	50	3	IPR011029
Domain	Spectrin_repeat	SPTA1 SYNE2	2.72e-03	29	50	2	IPR002017
Domain	Tudor	SETDB1 PHF20	2.91e-03	30	50	2	IPR002999
Domain	Spectrin/alpha-actinin	SPTA1 SYNE2	3.31e-03	32	50	2	IPR018159
Domain	SPEC	SPTA1 SYNE2	3.31e-03	32	50	2	SM00150
Domain	-	BPTF PHF20 TRIM35 RFFL USP33	6.84e-03	449	50	5	3.30.40.10
Domain	Znf_FYVE_PHD	BPTF PHF20 RFFL	7.15e-03	147	50	3	IPR011011
Domain	Znf_RING/FYVE/PHD	BPTF PHF20 TRIM35 RFFL USP33	7.49e-03	459	50	5	IPR013083
Domain	EFh	S100A9 SPTA1 RCN1	8.70e-03	158	50	3	SM00054
Domain	-	DPYD MICAL3	9.86e-03	56	50	2	3.50.50.60
Domain	FAD/NAD-binding_dom	DPYD MICAL3	1.02e-02	57	50	2	IPR023753
Pathway	REACTOME_MUSCLE_CONTRACTION	MYH11 CALD1 ATP1A4 DYSF KCNK9 NOS1	2.11e-05	203	40	6	M5485
Pathway	REACTOME_MUSCLE_CONTRACTION	MYH11 CALD1 ATP1A4 KCNK9 NOS1	9.77e-05	165	40	5	MM15026
Pathway	REACTOME_SMOOTH_MUSCLE_CONTRACTION	MYH11 CALD1 DYSF	2.41e-04	43	40	3	M1429
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	BPTF MYH11 ANK2 CALD1 HOOK1 SPTA1 CTAGE1 SYNE2 EIF4G1 RCN1 ABCF2 ATP1A4 HSPA6 HCLS1 DDX5	5.60e-09	1442	56	15	35575683
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYH11 ANK2 CALD1 MAP1A SPTA1 EIF4G1 IQSEC1 MICAL3 SPECC1L OLA1 RAPGEF2 NOS1 DDX5	3.32e-07	1431	56	13	37142655
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MICALL1 NSFL1C CALD1 MAP1A EIF4G1 ABCF2 SPECC1L OLA1 DYSF	2.21e-06	724	56	9	36232890
Pubmed	cFLIPS regulates alternative NLRP3 inflammasome activation in human monocytes.	CFLAR NLRP3	2.55e-06	2	56	2	37591930
Pubmed	S100A9 blockade prevents lipopolysaccharide-induced lung injury via suppressing the NLRP3 pathway.	S100A9 NLRP3	2.55e-06	2	56	2	33549095
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MICALL1 CFLAR S100A9 HOOK1 EIF4G1 OLA1 HERC1 QRICH2 DDX5 PPM1B IPO11	5.38e-06	1284	56	11	17353931
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MYH11 PHF20 MAP1A ACOT11 SPTA1 ATP1A4 NOS1 DDX5	6.60e-06	621	56	8	22794259
Pubmed	S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.).	S100A9 NLRP3	7.63e-06	3	56	2	23977231
Pubmed	Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation.	S100A9 NLRP3	7.63e-06	3	56	2	33754072
Pubmed	A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis.	S100A9 NLRP3	1.52e-05	4	56	2	37335321
Pubmed	A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus.	CFLAR NLRP3	1.52e-05	4	56	2	29099934
Pubmed	Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.	GCH1 NOS1	1.52e-05	4	56	2	22798524
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ANK2 NSFL1C IQSEC1 MICAL3 NOS1	1.67e-05	197	56	5	36604605
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MICALL1 ANK2 NSFL1C CALD1 EIF4G1 ABCF2 MICAL3 DDX5	1.70e-05	708	56	8	39231216
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	BPTF CALD1 EIF4G1 MLH1 MICAL3 ZNF579	2.48e-05	360	56	6	33111431
Pubmed	Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD.	GCH1 NOS1	2.54e-05	5	56	2	20581851
Pubmed	MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.	MICALL1 MICAL3	2.54e-05	5	56	2	12110185
Pubmed	Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate.	PTPRO SPTA1	2.54e-05	5	56	2	23533167
Pubmed	Simultaneous dystrophin and dysferlin deficiencies associated with high-level expression of the coxsackie and adenovirus receptor in transgenic mice.	DYSF NOS1	2.54e-05	5	56	2	17148677
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	ANK2 SPTA1	2.54e-05	5	56	2	29720258
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	NSFL1C WDR87 EIF4G1 RCN1 MLH1 ABCF2 SPECC1L OLA1 DDX5 PPM1B	2.69e-05	1247	56	10	27684187
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MICALL1 BPTF NSFL1C EIF4G1 IQSEC1 RFFL MICAL3 ZNF579	3.21e-05	774	56	8	15302935
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	NSFL1C MICAL3 RAPGEF2 HSPA6 PPM1B USP33	3.25e-05	378	56	6	34315543
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	BPTF CALD1 SYNE2 EIF4G1 RCN1 ABCF2 SPECC1L OLA1 DDX5	3.51e-05	1024	56	9	24711643
Pubmed	Analysis of erythrocyte and platelet membrane proteins in various forms of beta-thalassemia.	ANK2 SPTA1	3.80e-05	6	56	2	15310273
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	S100A9 ABCF2 HERC1 DDX5 PPM1B	4.75e-05	245	56	5	35652658
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MYH11 CALD1 EIF4G1 RCN1 ABCF2 CCDC144CP HSPA6 DDX5	6.05e-05	847	56	8	35235311
Pubmed	PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.	NSFL1C EIF4G1 NLRP3	6.91e-05	49	56	3	31762063
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	S100A9 MYH11 SPTA1 HSPA6 DDX5	7.00e-05	266	56	5	19380743
Pubmed	cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.	CFLAR NLRP3	7.09e-05	8	56	2	32193329
Pubmed	USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer.	DDX5 PPM1B	7.09e-05	8	56	2	36864055
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	BPTF SETDB1 NSFL1C PTPRO SYNE2 EIF4G1 GCH1 ZNF579 DDX5	7.20e-05	1124	56	9	21900206
Pubmed	Proteomic analysis of the NOS2 interactome in human airway epithelial cells.	RCN1 HERC1 HSPA6 PPM1B	7.43e-05	138	56	4	23438482
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	EIF4G1 SPECC1L HERC1 PPM1B	7.64e-05	139	56	4	25476789
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CALD1 SYNE2 EIF4G1 RCN1 ABCF2 MICAL3 GCH1 SPECC1L HSPA6 IPO11	8.98e-05	1440	56	10	30833792
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK2 MAP1A IQSEC1 SPECC1L RAPGEF2	9.06e-05	281	56	5	28706196
Pubmed	Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.	DPYD MLH1	9.10e-05	9	56	2	19858398
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	DYSF NOS1	9.10e-05	9	56	2	16916601
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	NSFL1C CALD1 EIF4G1 RCN1 ABCF2 OLA1 HERC1 HSPA6 DDX5 IPO11	9.78e-05	1455	56	10	22863883
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	S100A9 EIF4G1 HERC1 USP33	1.03e-04	150	56	4	32423001
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 SPTA1	1.14e-04	10	56	2	22159418
Pubmed	The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA.	EIF4G1 DDX5	1.14e-04	10	56	2	23788676
Pubmed	A human MAP kinase interactome.	S100A9 SETDB1 MYH11 MAP1A SPECC1L RAPGEF2	1.30e-04	486	56	6	20936779
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	MSANTD3 ANK2 CALD1 MLH1 MICAL3 SPECC1L ZNF579 RAPGEF2 DDX5	1.30e-04	1215	56	9	15146197
Pubmed	Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner.	CFLAR NLRP3	1.39e-04	11	56	2	23144495
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANK2 HOOK1 SYNE2 EIF4G1 IQSEC1 SPECC1L RAPGEF2 NOS1	1.47e-04	963	56	8	28671696
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	S100A9 LCA5 RCN1 SPECC1L ZNF579 IPO11	1.56e-04	503	56	6	36217030
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	S100A9 CALD1 HSPA6 DDX5 PPM1B	1.59e-04	317	56	5	17620599
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	S100A9 MYH11 RCN1 ABCF2 PPM1B	1.84e-04	327	56	5	31409639
Pubmed	Genome-wide association study of antiphospholipid antibodies.	LCA5 MICAL3	1.96e-04	13	56	2	23509613
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	S100A9 BPTF EIF4G1 ABCF2	2.02e-04	179	56	4	36261009
Pubmed	Activity of caspase-8 determines plasticity between cell death pathways.	CFLAR NLRP3	2.29e-04	14	56	2	31723262
Pubmed	An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.	SETDB1 PHF20	2.29e-04	14	56	2	28981838
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	MYH11 CALD1 EIF4G1 SPECC1L	2.59e-04	191	56	4	33762435
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	S100A9 EIF4G1 ATP1A4 HSPA6 DDX5 PPM1B	2.73e-04	558	56	6	27591049
Pubmed	Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.	S100A9 RCN1 HSPA6 IPO11	2.80e-04	195	56	4	17110338
Pubmed	Agrin has a pathological role in the progression of oral cancer.	S100A9 MYH11 NSFL1C DDX5	2.91e-04	197	56	4	29872149
Pubmed	Luzp4 defines a new mRNA export pathway in cancer cells.	CALD1 SPECC1L DDX5	2.98e-04	80	56	3	25662211
Pubmed	Proteomic analysis of GTP cyclohydrolase 1 multiprotein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions.	GCH1 PPM1B	3.01e-04	16	56	2	19294699
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	S100A9 BPTF MAP1A PTPRO EIF4G1 IQSEC1 HSPA6 DDX5	3.23e-04	1082	56	8	38697112
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	S100A9 MYH11 CALD1 EIF4G1 SPECC1L DDX5	3.36e-04	580	56	6	35676659
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	MAP1A SPTA1	3.41e-04	17	56	2	8997639
Pubmed	Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.	HSPA6 DDX5 PPM1B	3.43e-04	84	56	3	25670202
Pubmed	TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.	CFLAR S100A9 BPTF HSPA6 DDX5	3.76e-04	382	56	5	37249651
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE2 SPECC1L RAPGEF2	3.81e-04	87	56	3	12465718
Pubmed	Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.	CALD1 HSPA6 DDX5	3.94e-04	88	56	3	25144556
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BPTF SETDB1 MAP1A RCN1 IQSEC1 MLH1 ZNF579 RAPGEF2	3.97e-04	1116	56	8	31753913
Pubmed	Germline Chd8 haploinsufficiency alters brain development in mouse.	ANK2 DDX5	4.75e-04	20	56	2	28671691
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NSFL1C CALD1 HOOK1 EIF4G1 RCN1 MICAL3 HSPA6 DDX5	4.82e-04	1149	56	8	35446349
Pubmed	Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.	MLH1 DDX5 PPM1B	4.93e-04	95	56	3	35896951
Pubmed	HEY1 functions are regulated by its phosphorylation at Ser-68.	SYNE2 IQSEC1 DDX5	4.93e-04	95	56	3	27129302
Pubmed	SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243.	MYH11 EIF4G1 SPECC1L	4.93e-04	95	56	3	33863777
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETDB1 ACOT11 MICAL3 ANKRD12 USP33	5.01e-04	407	56	5	12693553
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	CALD1 EIF4G1 RCN1 ABCF2 SPECC1L DDX5	5.02e-04	626	56	6	33644029
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	MAP1A SYNE2 ANKRD12	5.40e-04	98	56	3	34943047
Pubmed	Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.	MYH11 ANK2 ACOT11 IQSEC1	5.49e-04	233	56	4	29518331
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	S100A9 MYH11 EIF4G1 RCN1 DDX5	5.65e-04	418	56	5	35338135
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	MYH11 MICAL3 ANKRD12	5.72e-04	100	56	3	10048485
Pubmed	Smooth muscle contraction and relaxation.	MYH11 CALD1	5.76e-04	22	56	2	14627618
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	ANK2 SYNE2 EIF4G1	5.89e-04	101	56	3	26949739
Pubmed	Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.	CALD1 EIF4G1 HSPA6 DDX5	6.52e-04	244	56	4	28902428
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	CALD1 MAP1A EIF4G1 HSPA6 DDX5	7.42e-04	444	56	5	34795231
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	MICALL1 ANK2 NSFL1C EIF4G1 USP33	7.80e-04	449	56	5	31732153
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	SETDB1 ABCF2 ATP1A4 HSPA6	7.80e-04	256	56	4	35777956
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	S100A9 MYH11 CALD1 ABCF2 SPECC1L HSPA6 DDX5	7.98e-04	949	56	7	36574265
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	MYH11 EIF4G1 DDX5 PPM1B	8.03e-04	258	56	4	37794589
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	ANK2 NSFL1C ABCF2 HSPA6	9.12e-04	267	56	4	33417871
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	S100A9 EIF4G1 ABCF2 SPECC1L	9.24e-04	268	56	4	33024031
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	MYH11 CALD1 EIF4G1	9.26e-04	118	56	3	30979931
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	BPTF ANK2 ATP1A4 DDX5	9.63e-04	271	56	4	32433965
Pubmed	YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.	MYH11 CALD1	1.01e-03	29	56	2	32520726
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	SYNE2 HERC1 DDX5 PPM1B	1.04e-03	277	56	4	30745168
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	SETDB1 NSFL1C OLA1 HERC1 PPM1B	1.06e-03	481	56	5	28190767
Pubmed	A genetic linkage map of the mouse: current applications and future prospects.	MICALL1 CALD1	1.08e-03	30	56	2	8211130
Pubmed	Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.	RCN1 DDX5	1.08e-03	30	56	2	24140279
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DPYD MICAL3 HERC1 DYSF IPO11	1.22e-03	497	56	5	36774506
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	EIF4G1 ABCF2 HSPA6 DDX5	1.32e-03	295	56	4	26209609
Pubmed	HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.	MYH11 DYSF DDX5	1.36e-03	135	56	3	23874603
Pubmed	Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.	EIF4G1 DDX5	1.38e-03	34	56	2	16611982
Pubmed	Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.	MAP1A HSPA6	1.38e-03	34	56	2	20391533
Interaction	HERC2 interactions	ANK2 HOOK1 SYNE2 EIF4G1 SPECC1L HERC1 PPM1B USP33 IPO11	6.86e-06	503	54	9	int:HERC2
Interaction	KCTD13 interactions	MYH11 ANK2 NSFL1C CALD1 MAP1A SPTA1 EIF4G1 IQSEC1 MICAL3 SPECC1L OLA1 RAPGEF2 NOS1 DDX5	1.27e-05	1394	54	14	int:KCTD13
Interaction	KCNA3 interactions	MICALL1 ANK2 NSFL1C CALD1 HOOK1 EIF4G1 ABCF2 MICAL3 SPECC1L HCLS1 DDX5	1.61e-05	871	54	11	int:KCNA3
Interaction	OTUD7A interactions	ANK2 NSFL1C MICAL3 NOS1	1.75e-05	58	54	4	int:OTUD7A
Interaction	IFT56 interactions	LCA5 HOOK1 ZNF579 HERC1	2.44e-05	63	54	4	int:IFT56
Interaction	MAGEA3 interactions	S100A9 BPTF IQSEC1 DDX5 PPM1B	2.94e-05	134	54	5	int:MAGEA3
Interaction	SHC1 interactions	S100A9 MYH11 CALD1 SPTA1 RFFL HSPA6 DDX5	4.88e-05	362	54	7	int:SHC1
Interaction	CTNNB1 interactions	ENKUR ANK2 NSFL1C AUH SYNE2 ABCF2 SPECC1L RAPGEF2 HCLS1 DDX5 USP33	6.19e-05	1009	54	11	int:CTNNB1
Cytoband	1q21	S100A9 SETDB1 SPTA1	1.94e-04	91	56	3	1q21
Cytoband	7q33	CALD1 AGBL3	1.16e-03	41	56	2	7q33
Cytoband	Ensembl 112 genes in cytogenetic band chr7q33	CALD1 AGBL3	2.31e-03	58	56	2	chr7q33
Cytoband	Ensembl 112 genes in cytogenetic band chr1q23	SPTA1 ATP1A4 HSPA6	2.69e-03	226	56	3	chr1q23
GeneFamily	Tudor domain containing	SETDB1 PHF20	2.59e-03	37	37	2	780
GeneFamily	LIM domain containing	MICALL1 MICAL3	6.48e-03	59	37	2	1218
GeneFamily	EF-hand domain containing	S100A9 SPTA1 RCN1	1.01e-02	219	37	3	863
GeneFamily	PHD finger proteins	BPTF PHF20	1.46e-02	90	37	2	88
Coexpression	GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN	CFLAR MSANTD3 GCH1 SPECC1L RAPGEF2 NLRP3	3.46e-06	196	55	6	M5849
Coexpression	GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	CFLAR MSANTD3 GCH1 RAPGEF2 NLRP3 DDX5	3.56e-06	197	55	6	M5860
Coexpression	GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP	CFLAR MSANTD3 GCH1 RAPGEF2 NLRP3 DDX5	3.56e-06	197	55	6	M5867
Coexpression	GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP	CFLAR GCH1 SPECC1L RAPGEF2 NLRP3 DDX5	3.56e-06	197	55	6	M5858
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BPTF SETDB1 DPYD PHF20 AUH SYNE2 MICAL3 SPECC1L RAPGEF2 PPM1B	1.01e-05	856	55	10	M4500
Coexpression	TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL	CFLAR S100A9 DPYD EIF4G1 GCH1 RAPGEF2 DYSF HCLS1 NLRP3	1.82e-05	724	55	9	M41700
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	CFLAR MYH11 ANK2 AUH GCH1 DDX5 PPM1B USP33	2.30e-05	568	55	8	M4023
Coexpression	GSE27859_MACROPHAGE_VS_DC_UP	CFLAR RCN1 RFFL RAPGEF2 NLRP3	2.74e-05	168	55	5	M8590
Coexpression	SCHERER_PBMC_APSV_WETVAX_AGE_18_32YO_5_TO_7DY_UP	S100A9 DPYD RCN1 GCH1 DYSF NLRP3	2.91e-05	285	55	6	M40879
Coexpression	NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	CFLAR RCN1 GCH1 HCLS1	2.96e-05	84	55	4	M1448
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	DPYD CALD1 ANKRD12 HERC1 RAPGEF2	3.51e-05	177	55	5	M39245
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	BPTF DPYD AUH MICAL3 SPECC1L RAPGEF2 PPM1B	5.21e-05	466	55	7	M13522
Coexpression	NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	CFLAR RCN1 GCH1 HCLS1	5.63e-05	99	55	4	MM1152
Coexpression	GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	CFLAR MSANTD3 GCH1 RAPGEF2 NLRP3	5.71e-05	196	55	5	M5873
Coexpression	GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN	CFLAR GCH1 SPECC1L RAPGEF2 NLRP3	5.99e-05	198	55	5	M5847
Coexpression	GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN	CFLAR GCH1 SPECC1L RAPGEF2 NLRP3	6.13e-05	199	55	5	M5845
Coexpression	GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP	CFLAR RCN1 ANKRD12 HERC1 DDX5	6.13e-05	199	55	5	M6001
Coexpression	GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN	CFLAR MYH11 RCN1 PPP1R2P1 DDX5	6.28e-05	200	55	5	M6894
Coexpression	GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN	CFLAR S100A9 GCH1 HSPA6 NLRP3	6.28e-05	200	55	5	M9968
Coexpression	GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN	CFLAR PTPRO GCH1 RAPGEF2 NLRP3	6.28e-05	200	55	5	M8643
Coexpression	GRUETZMANN_PANCREATIC_CANCER_UP	CFLAR BPTF DPYD CALD1 SPTA1 RCN1	1.04e-04	359	55	6	M15193
Coexpression	HOWARD_PBMC_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_19_39YO_AS03_ADJUVANT_VS_BUFFER_1DY_UP	S100A9 DPYD GCH1 DYSF HSPA6 NLRP3	1.36e-04	377	55	6	M40997
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CFLAR CTAGE1 RAPGEF2 HSPA6 NLRP3	3.73e-06	190	55	5	4d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ANK2 CALD1 ACOT11 MICAL3 DYSF	3.83e-06	191	55	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	343B-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 DYSF NLRP3	4.03e-06	193	55	5	24c06b0461894fe9f68bf26507d7a708468237c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	S100A9 DPYD GCH1 HCLS1 NLRP3	4.24e-06	195	55	5	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	S100A9 DPYD HSPA6 HCLS1 NLRP3	4.45e-06	197	55	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100A9 GCH1 HSPA6 HCLS1 NLRP3	4.57e-06	198	55	5	7015b9f5ead65937e056d746340d44d0655d6a3e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100A9 GCH1 HSPA6 HCLS1 NLRP3	4.57e-06	198	55	5	6edf6c547e8a3aa2b23df4662bf59ed38caa9e5e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	S100A9 DPYD HSPA6 HCLS1 NLRP3	4.68e-06	199	55	5	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BPTF SYNE2 ANKRD12 HERC1 DDX5	4.68e-06	199	55	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100A9 SPTA1 GCH1 HERC1	5.02e-05	164	55	4	f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCell	facs-MAT-Fat-18m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100A9 PTPRO HCLS1 NLRP3	5.26e-05	166	55	4	9116be2805c34881debb999d8417e43832fcf2f2
ToppCell	facs-MAT-Fat-18m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100A9 PTPRO HCLS1 NLRP3	5.26e-05	166	55	4	5c2667da79935f3d4b1edbfe7a10e7dbc2fa3ad0
ToppCell	facs-MAT-Fat-24m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100A9 PTPRO HCLS1 NLRP3	5.51e-05	168	55	4	6514a27a54ea0f07172b3a73270250143a7b14f0
ToppCell	facs-MAT-Fat-24m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100A9 PTPRO HCLS1 NLRP3	5.51e-05	168	55	4	0b6bb335e93476b13955543eeb487243b0067369
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 CALD1 MAP1A WDR87	5.91e-05	171	55	4	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 CALD1 MAP1A WDR87	5.91e-05	171	55	4	09e653973962fb884878089d281f0947f7a285f6
ToppCell	COVID-19_Severe-Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	CFLAR S100A9 SYNE2 HSPA6	7.36e-05	181	55	4	5e5101195d5ff8c8ea7ddcf0bc4f4e03e64c01e0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LCA5 ENKUR MAP1A SPTA1	7.36e-05	181	55	4	9dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell	COVID-19_Severe-Neutrophil\|COVID-19_Severe / Disease condition and Cell class	CFLAR S100A9 SYNE2 HSPA6	7.36e-05	181	55	4	aa5e5fb0308b5e2ef918548c85529c9a433c57f5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LCA5 ENKUR MAP1A SPTA1	7.36e-05	181	55	4	14c2dd946e89ba578711c2d25935b6b3d319b701
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LCA5 ENKUR MAP1A SPTA1	7.36e-05	181	55	4	c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LCA5 ENKUR MAP1A SPTA1	7.36e-05	181	55	4	fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell	LPS_only-Myeloid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFLAR S100A9 HCLS1 NLRP3	7.52e-05	182	55	4	666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	S100A9 DPYD GCH1 NLRP3	7.85e-05	184	55	4	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 MICAL3 HERC1 RAPGEF2	8.01e-05	185	55	4	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	saliva-Severe-critical_progression_d28-40\|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE2 GCH1 DYSF DDX5	8.18e-05	186	55	4	0095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCell	wk_08-11-Hematologic-Myeloid-Cycling_DC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	S100A9 PTPRO HCLS1 NLRP3	8.18e-05	186	55	4	de1f0bc5dbf6dc0e716f5ebbf2bbcfe249811c54
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 CALD1 TRIM35 DYSF	8.35e-05	187	55	4	e1b41560c26795a7d353b9468b1bb6fc7c6b379e
ToppCell	control-Myeloid-Neutrophils_4\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CFLAR S100A9 DYSF HSPA6	8.52e-05	188	55	4	22d76c222fb0e3da08e10191af0090f14e03f2ad
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SYNE2 ANKRD12 HERC1 RAPGEF2	8.52e-05	188	55	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LCA5 DPYD FAM153B RAPGEF2	8.52e-05	188	55	4	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 ACOT11 EIF4G1 DDX5	8.52e-05	188	55	4	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MSANTD3 FAM153B CALD1 OLA1	8.52e-05	188	55	4	e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCell	COPD-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	S100A9 GCH1 DYSF NLRP3	8.70e-05	189	55	4	6294691231c7d38707323cf31578a107d3b2c622
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 MICAL3 HERC1 RAPGEF2	8.70e-05	189	55	4	1900e574870fc647bfa11c732a72f3d38aab717c
ToppCell	mild-Others\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	S100A9 ENKUR MAP1A HSPA6	8.88e-05	190	55	4	782dc1b612ac1faad7cc2781bfda92a079830d38
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYH11 ANK2 CALD1 RCN1	9.06e-05	191	55	4	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCell	mild-Others-Megakaryocytes\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	S100A9 ENKUR MAP1A HSPA6	9.06e-05	191	55	4	0b36223bd7f5758cc37194da6cc252f613bc3c97
ToppCell	COVID-19-kidney-Myeloid\|kidney / Disease (COVID-19 only), tissue and cell type	S100A9 DPYD DYSF HCLS1	9.25e-05	192	55	4	441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	S100A9 DYSF HCLS1 NLRP3	9.25e-05	192	55	4	d44f46352bac414b45cc749f7cbdc3a159bd7ae8
ToppCell	367C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.25e-05	192	55	4	26326d7c3d907d754e85e128b7d8a52e90863f3f
ToppCell	367C-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.43e-05	193	55	4	c7ecd98729419b34c14f9b387b15472c47951d2f
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	S100A9 DYSF HSPA6 NLRP3	9.43e-05	193	55	4	93ba635ed69fec9286fe7636b9d258f3d93a22c3
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	S100A9 DYSF HSPA6 NLRP3	9.43e-05	193	55	4	6dfdeb793cb5ad6412b6f808b5687a4e74b6ec65
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	S100A9 DYSF HSPA6 NLRP3	9.62e-05	194	55	4	e455cb469157c044126f9b0b308957d4ee1e608b
ToppCell	368C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.62e-05	194	55	4	f9b9cbd1a418a7cbd151c2425fda6b864db9aa82
ToppCell	356C-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.62e-05	194	55	4	3f9ac1de8605a7930f49a7ce0e32aea9997d7791
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	S100A9 DYSF HSPA6 NLRP3	9.62e-05	194	55	4	e0cfd18a7ea2251163d61312b9397f8a518c8c51
ToppCell	Monocytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	S100A9 GCH1 HCLS1 NLRP3	9.62e-05	194	55	4	fa6a2794baa6be6298f415330ff51b26a5402571
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPYD GCH1 HSPA6 NLRP3	9.62e-05	194	55	4	dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCell	356C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.62e-05	194	55	4	a41cde3088b43670210daab4f43a24aa83dbd45b
ToppCell	343B-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.82e-05	195	55	4	ff87a33f9a48765bfa9408f686985feefeff2adf
ToppCell	343B-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	S100A9 GCH1 HSPA6 NLRP3	9.82e-05	195	55	4	d1ec768573929c717bb6b20ad5f26c4549cfcaed
ToppCell	MNPs-Monocytes\|MNPs / lung cells shred on cell class, cell subclass, sample id	S100A9 GCH1 HCLS1 NLRP3	9.82e-05	195	55	4	45e8d27287bdfd07d7e944ae5d3f44d05c33468f
ToppCell	368C-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	9.82e-05	195	55	4	8da933942e9033e18e25ab47831c269747b1c0b2
ToppCell	Mild_COVID-19-Myeloid-MoAM3\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	S100A9 DYSF HSPA6 NLRP3	1.00e-04	196	55	4	9faad17aa0b6af5a8ec2dadf7d70b9209d658072
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD HSPA6 HCLS1 NLRP3	1.00e-04	196	55	4	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	distal-3-Hematologic-Nonclassical_Monocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 GCH1 HCLS1 NLRP3	1.00e-04	196	55	4	c1f3334bc09f5d0cfb9d998a3a64f0700426a357
ToppCell	(3)_MNP-(3)_Monocyte\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFLAR S100A9 GCH1 NLRP3	1.00e-04	196	55	4	83af2eb1c28dfe7678d972be1d6d358c4a94731d
ToppCell	(0)_Myeloid-(000)_CD14+_Monocyte\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	S100A9 DPYD DYSF NLRP3	1.00e-04	196	55	4	e9718642ee2751c9d46a1b968547bdcb59cdfd30
ToppCell	medial-2-Hematologic-Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 DPYD HCLS1 NLRP3	1.02e-04	197	55	4	fbff79d6ece1605126ae0caa0c71253ea557779c
ToppCell	medial-Hematologic-Classical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 DPYD HCLS1 NLRP3	1.02e-04	197	55	4	3960eac4b6753e3294e13901f6ea13d894275c8d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD HSPA6 HCLS1 NLRP3	1.02e-04	197	55	4	6ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell	390C-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFLAR S100A9 GCH1 NLRP3	1.02e-04	197	55	4	cd941c5ef76897047bd8508d98510c4ff164d223
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 ANKRD12 HERC1 DDX5	1.02e-04	197	55	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	medial-Hematologic-Classical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 DPYD HCLS1 NLRP3	1.02e-04	197	55	4	ae2b51d4e91126ee0a0f69c040297c2a78ce27dd
ToppCell	COVID-19-Myeloid-MoAM1,_IL1R2\|COVID-19 / Condition, Lineage and Cell class	S100A9 GCH1 RAPGEF2 HSPA6	1.02e-04	197	55	4	4a9c61b37c938bb26929593007d713382ae1eb79
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD HSPA6 HCLS1 NLRP3	1.02e-04	197	55	4	dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD HSPA6 HCLS1 NLRP3	1.02e-04	197	55	4	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	343B-Myeloid-Monocyte-CD16+_Monocyte\|343B / Donor, Lineage, Cell class and subclass (all cells)	S100A9 GCH1 HSPA6 NLRP3	1.02e-04	197	55	4	8d6551e118cfe308088487c6d5171d986f90fb2f
ToppCell	COVID-19_Severe-Classical_Monocyte\|World / disease group, cell group and cell class	S100A9 DPYD DYSF NLRP3	1.02e-04	197	55	4	344801997b89bd81d8d5c3c872934de523233a8d
ToppCell	severe-Others-Megakaryocytes\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CFLAR S100A9 DYSF HSPA6	1.02e-04	197	55	4	fc0864e2de2d9f99084586b467551b6da535d933
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD HSPA6 HCLS1 NLRP3	1.02e-04	197	55	4	72cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCell	10x3'2.3-week_17-19-Myeloid_monocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFLAR S100A9 GCH1 NLRP3	1.04e-04	198	55	4	100091c91fde604daf110f20b44505f240f93ae8
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	S100A9 DPYD HCLS1 NLRP3	1.04e-04	198	55	4	a6aa113f0af4d25c032f440c3134fe4d88ca5055
ToppCell	Mild-Myeloid-Macrophages-FCN1_high\|Mild / Condition, Lineage, Cell class and cell subclass	S100A9 GCH1 HSPA6 NLRP3	1.04e-04	198	55	4	17aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	S100A9 DPYD HCLS1 NLRP3	1.04e-04	198	55	4	a0ceed8689d42be6b9cde89d6c182d10b3fb14fc
ToppCell	COVID-19_Severe-Classical_Monocyte\|COVID-19_Severe / disease group, cell group and cell class	S100A9 DPYD DYSF NLRP3	1.04e-04	198	55	4	b88c4c0ed1abf0a28dbe05b04b9bee1073855ba8
ToppCell	10x3'2.3-week_17-19-Myeloid_monocytic-monocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFLAR S100A9 GCH1 NLRP3	1.04e-04	198	55	4	73e9ada6998c09ae3a3a66e920b28694b7f9cf6b
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	DPYD HSPA6 HCLS1 NLRP3	1.04e-04	198	55	4	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM153B MYH11 CALD1 DYSF	1.04e-04	198	55	4	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	S100A9 DPYD DYSF NLRP3	1.04e-04	198	55	4	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	S100A9 DPYD DYSF NLRP3	1.06e-04	199	55	4	9314eb9a89407738626a0384884454b5f9031ee7
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	LCA5 BPTF SYNE2 ANKRD12	1.06e-04	199	55	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	S100A9 SYNE2 IQSEC1 DYSF	1.06e-04	199	55	4	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	Transverse-T_cell-Th1\|T_cell / Region, Cell class and subclass	MAP1A HSPA6 NLRP3 DDX5	1.06e-04	199	55	4	9271d9d36ffe1c169049d4340258f366916adfaf
ToppCell	distal-2-Hematologic-Intermediate_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 HSPA6 HCLS1 NLRP3	1.06e-04	199	55	4	5e209df67cfe8ac7437cc363f1c5c3166bfae1af
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	BPTF CALD1 SYNE2 ANKRD12	1.06e-04	199	55	4	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	BPTF CALD1 SYNE2 ANKRD12	1.06e-04	199	55	4	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	critical\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFLAR S100A9 ANKRD12 IPO11	1.06e-04	199	55	4	16c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A9 GCH1 HCLS1 NLRP3	1.06e-04	199	55	4	d3f77acb36ac7c56a47ca98b695f46ae5b9ecd12
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	LCA5 BPTF SYNE2 ANKRD12	1.06e-04	199	55	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_only-Hematopoietic_Myeloid\|LPS_only / Treatment groups by lineage, cell group, cell type	CFLAR S100A9 HCLS1 NLRP3	1.06e-04	199	55	4	20523dee39a4c5f6423259920f108127b47525c4
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	BPTF DPYD ANK2 ANKRD12	1.06e-04	199	55	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	10x3'2.3-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFLAR S100A9 GCH1 NLRP3	1.06e-04	199	55	4	50a30d5ee99e51743a0dd60144fc341ff68da9af
ToppCell	distal-Hematologic-Intermediate_Monocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 HSPA6 HCLS1 NLRP3	1.06e-04	199	55	4	f393f8d2b9711e71beb4f1c5e7cac5acb047fd0e
ToppCell	distal-Hematologic-Intermediate_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	S100A9 HSPA6 HCLS1 NLRP3	1.06e-04	199	55	4	fa362f3e456a4853652e52d54e76473809eea76d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	BPTF DPYD ANK2 ANKRD12	1.06e-04	199	55	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	(1)_T_cell-(12)_Th1\|(1)_T_cell / shred on Cell_type and subtype	MAP1A SYNE2 HSPA6 NLRP3	1.06e-04	199	55	4	15133e0a4ea6cfcc27c1d438d9e854879ea84c30
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	S100A9 DPYD DYSF NLRP3	1.06e-04	199	55	4	dbf0bf09896c46155ae6fbd6307f097799e7e34e
Computational	Genes upregulated in subsets of cells of a given type within various tumors	CFLAR BPTF ANKRD12 DDX5	2.51e-05	49	38	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Muscle genes.	MYH11 CALD1 NOS1	2.92e-04	37	38	3	MODULE_512
Computational	Genes in the cancer module 387.	MYH11 CALD1 NOS1	6.71e-04	49	38	3	MODULE_387
Computational	Genes in the cancer module 201.	MYH11 CALD1 NOS1	7.12e-04	50	38	3	MODULE_201
Computational	Genes upregulated in subsets of cells of a given type within various tumors	ANKRD12 HSPA6 DDX5	7.12e-04	50	38	3	GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
Computational	Genes in the cancer module 329.	MYH11 CALD1 NOS1	7.55e-04	51	38	3	MODULE_329
Drug	Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; HL60; HT_HG-U133A	CFLAR PHF20 ANK2 NSFL1C ABCF2 RAPGEF2	7.92e-06	197	55	6	2994_DN
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HG-U133A	SETDB1 IQSEC1 ANKRD12 HERC1 RAPGEF2 HCLS1	8.39e-06	199	55	6	1960_DN
Disease	serum gamma-glutamyl transferase measurement	S100A9 BPTF CALD1 MAP1A GSTT4 MLH1 MICAL3 SPECC1L CCDC171	3.84e-05	914	54	9	EFO_0004532
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK1 SYNE2	2.14e-04	12	54	2	DOID:11726 (implicated_via_orthology)
Disease	antiphospholipid antibody measurement	LCA5 MICAL3	9.60e-04	25	54	2	EFO_0005200
Disease	bilirubin measurement	HOOK1 AUH SPTA1 CCDC171 NLRP3	1.28e-03	442	54	5	EFO_0004570
Disease	colorectal cancer (implicated_via_orthology)	DPYD MLH1	1.38e-03	30	54	2	DOID:9256 (implicated_via_orthology)
Disease	resting heart rate, chronic obstructive pulmonary disease	CTAGE1 HERC1	1.38e-03	30	54	2	EFO_0000341, EFO_0004351
Disease	FEV/FEC ratio	CALD1 CTAGE1 SYNE2 MICAL3 HERC1 CCDC171 DDX5 PPM1B	1.67e-03	1228	54	8	EFO_0004713
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	CALD1 DYSF HSPA6	1.80e-03	131	54	3	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	CALD1 DYSF HSPA6	1.80e-03	131	54	3	C4552091
Disease	Juvenile arthritis	CALD1 DYSF HSPA6	1.80e-03	131	54	3	C3495559
Disease	Juvenile psoriatic arthritis	CALD1 DYSF HSPA6	1.80e-03	131	54	3	C3714758

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLEKEAERLAHEDAE	ABCF2	171	Q9UG63
EMERHITLEKVFEDS	AGBL3	586	Q8NEM8
KVDEMISHATEELET	CTAGE1	386	Q96RT6
KNEMESHIRETALEE	CCDC171	191	Q6TFL3
MKETIFELEDEVEQH	SPECC1L	686	Q69YQ0
RTEEEKMEHSVAAER	ACOT11	166	Q8WXI4
EDEDQMVHLKADVVI	DPYD	421	Q12882
EVEEEMEKHRSNSTE	CCDC144CP	476	Q8IYA2
DDDEEINKMIDDRHI	ANKRD12	366	Q6UB98
EEMREEIHRHMDITE	BPTF	521	Q12830
IHQVEEALDTDEKEM	CFLAR	6	O15519
EHMKEIVVLETLEDI	RCN1	201	Q15293
TEEIQIAMKHDEVDI	QRICH2	1581	Q9H0J4
EIIHEELQLKDEEMI	OLA1	146	Q9NTK5
SDHEMREEEKLKAEE	KCNK9	31	Q9NPC2
EEESHRESEVPKEKM	ANK2	2101	Q01484
ERMAVEDHLKTEEEL	MICAL3	1936	Q7RTP6
DVIEKAELEEMEEVH	MAP1A	651	P78559
MKTEDELRVRHLEEE	AUH	71	Q13825
ISKDLHDDDKVEEML	PPP1R2P1	161	Q96PQ5
DLRESIAEVQEMEKH	IQSEC1	856	Q6DN90
LMSHLEEPKVTEDEE	IPO11	896	Q9UI26
EEEEREHEVMTAGKI	HERC1	1371	Q15751
HDVEKDEKLIRLMEE	DDX5	321	P17844
MEREEKFVTDEELHV	LCA5	386	Q86VQ0
EEDIHGEMDTIERRL	MICALL1	681	Q8N3F8
IERECEMAEEEHRIK	MSANTD3	226	Q96H12
VNLDMEDHRDEDFVK	NSFL1C	231	Q9UNZ2
AHMERLEEVNKEIDT	NOS1	381	P29475
MVDEEAHEFVAELKE	PTPRO	376	Q16827
EEVSAEKMEHAVEEV	GSTT4	126	A0A1W2PR19
EVEEEMEKHRSNSTE	CCDC144B	526	Q3MJ40
EEEMKQLEHDIGIIE	ENKUR	231	Q8TC29
TIDQIHKEAEMEEHR	EIF4G1	1001	Q04637
RLSKEEVERMVHEAE	HSPA6	511	P17066
EAHMEKLTEVHEELQ	HOOK1	551	Q9UJC3
EMTLEIVAESEHEER	DYSF	1986	O75923
EDVLGVHMVDKDTER	FAM153B	71	P0C7A2
DEVTHRMDSIEKELD	PHF20	951	Q9BVI0
EEEEEKEGRHLDMVQ	NLRP3	691	Q96P20
HEIERLQMEMKEDDV	TRIM35	236	Q9UPQ4
EKVIEHIMEDLDTNA	S100A9	56	P06702
VLDEYEEEKRHLQEM	SYNE2	1476	Q8WXH0
VSEEHDVLRKKEMES	HCLS1	61	P14317
HDISTEMCREKEELV	RFFL	116	Q8WZ73
IFDEDHDEMVIVKDI	GCH1	121	P30793
ELDKHLESRVEEIME	PPM1B	311	O75688
KRHREDSDVEMVEDD	MLH1	471	P40692
SMEELRHFIDEELEK	SETDB1	36	Q15047
ISHHEKMEEEDKERA	CALD1	251	Q05682
EVVMDDHKLTLEELS	ATP1A4	46	Q13733
EEILHEMEARLEEEE	MYH11	921	P35749
EEEGEIVMVKEHREL	RAPGEF2	246	Q9Y4G8
HEASDEVREKMEILD	SPTA1	441	P02549
FEMEEEEVDSKAHLR	ZNF579	541	Q8NAF0
KEEDEHFLEMRLSKD	WDR87	841	Q6ZQQ6
DLLHEELKEQVMEVE	USP33	281	Q8TEY7