| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF512B IRF9 ZNF263 HSFX4 FOXO6 TFAP2E DUX4L9 HSFX3 DUX4L2 ZNF397 DUX4 DUX4L4 | 1.05e-04 | 1459 | 47 | 12 | GO:0000977 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | ZNF512B IRF9 ZNF263 FOXO6 TFAP2E DUX4L9 HSFX3 DUX4L2 ZNF397 DUX4 DUX4L4 | 3.46e-04 | 1412 | 47 | 11 | GO:0000981 |
| GeneOntologyMolecularFunction | transcription coactivator activity | 7.09e-04 | 303 | 47 | 5 | GO:0003713 | |
| GeneOntologyMolecularFunction | C2H2 zinc finger domain binding | 7.21e-04 | 17 | 47 | 2 | GO:0070742 | |
| GeneOntologyMolecularFunction | mitogen-activated protein kinase kinase kinase binding | 1.70e-03 | 26 | 47 | 2 | GO:0031435 | |
| GeneOntologyMolecularFunction | transcription coregulator activity | 1.95e-03 | 562 | 47 | 6 | GO:0003712 | |
| HumanPheno | Chronic constipation | 3.37e-05 | 120 | 9 | 4 | HP:0012450 | |
| Pubmed | 1.13e-20 | 12 | 55 | 8 | 10433963 | ||
| Pubmed | 2.94e-20 | 13 | 55 | 8 | 17668377 | ||
| Pubmed | The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein. | 1.33e-19 | 8 | 55 | 7 | 17588759 | |
| Pubmed | 1.99e-18 | 10 | 55 | 7 | 17984056 | ||
| Pubmed | 2.83e-17 | 13 | 55 | 7 | 7739628 | ||
| Pubmed | Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. | 3.19e-16 | 17 | 55 | 7 | 11245978 | |
| Pubmed | The homeobox transcription factor DUXBL controls exit from totipotency. | 1.50e-08 | 4 | 55 | 3 | 38509386 | |
| Pubmed | 1.50e-08 | 4 | 55 | 3 | 17911620 | ||
| Pubmed | 3.73e-08 | 5 | 55 | 3 | 20063414 | ||
| Pubmed | The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection. | 1.30e-07 | 7 | 55 | 3 | 30765463 | |
| Pubmed | 1.68e-06 | 15 | 55 | 3 | 30071041 | ||
| Pubmed | 1.68e-06 | 15 | 55 | 3 | 35727972 | ||
| Pubmed | 2.46e-06 | 2 | 55 | 2 | 24145033 | ||
| Pubmed | 2.46e-06 | 2 | 55 | 2 | 23519644 | ||
| Pubmed | 2.46e-06 | 2 | 55 | 2 | 8268913 | ||
| Pubmed | 7.51e-06 | 170 | 55 | 5 | 15057823 | ||
| Pubmed | DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation. | 1.47e-05 | 4 | 55 | 2 | 19829708 | |
| Pubmed | 2.45e-05 | 5 | 55 | 2 | 19359275 | ||
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | 5.99e-05 | 430 | 55 | 6 | 35044719 | |
| Pubmed | DUX is a non-essential synchronizer of zygotic genome activation. | 6.96e-05 | 50 | 55 | 3 | 31806660 | |
| Pubmed | Interaction network of human early embryonic transcription factors. | 2.34e-04 | 351 | 55 | 5 | 38297188 | |
| Pubmed | A systematic survey of loss-of-function variants in human protein-coding genes. | 5.56e-04 | 22 | 55 | 2 | 22344438 | |
| Pubmed | Identification of a large set of rare complete human knockouts. | 6.63e-04 | 24 | 55 | 2 | 25807282 | |
| Pubmed | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers. | 7.37e-04 | 954 | 55 | 7 | 36373674 | |
| Pubmed | ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1. | 7.75e-04 | 113 | 55 | 3 | 34474245 | |
| Pubmed | 8.64e-04 | 268 | 55 | 4 | 33640491 | ||
| Pubmed | 1.18e-03 | 32 | 55 | 2 | 32487729 | ||
| Pubmed | The mutational constraint spectrum quantified from variation in 141,456 humans. | 1.18e-03 | 32 | 55 | 2 | 32461654 | |
| Pubmed | FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability. | 1.18e-03 | 32 | 55 | 2 | 35813202 | |
| Pubmed | 1.33e-03 | 34 | 55 | 2 | 28162770 | ||
| Interaction | ZNF683 interactions | 9.80e-12 | 10 | 44 | 5 | int:ZNF683 | |
| Interaction | CELF4 interactions | 1.79e-11 | 11 | 44 | 5 | int:CELF4 | |
| Interaction | BEND2 interactions | 3.07e-11 | 12 | 44 | 5 | int:BEND2 | |
| Interaction | PTTG2 interactions | 7.74e-11 | 14 | 44 | 5 | int:PTTG2 | |
| Interaction | MBNL3 interactions | 1.68e-10 | 16 | 44 | 5 | int:MBNL3 | |
| Interaction | FAM222B interactions | 3.76e-10 | 42 | 44 | 6 | int:FAM222B | |
| Interaction | PRR34 interactions | 7.78e-10 | 21 | 44 | 5 | int:PRR34 | |
| Interaction | TPRX1 interactions | 7.78e-10 | 21 | 44 | 5 | int:TPRX1 | |
| Interaction | C1orf94 interactions | 2.43e-09 | 103 | 44 | 7 | int:C1orf94 | |
| Interaction | C3orf36 interactions | 2.49e-09 | 26 | 44 | 5 | int:C3orf36 | |
| Interaction | VENTX interactions | 2.60e-09 | 104 | 44 | 7 | int:VENTX | |
| Interaction | SH3RF1 interactions | 3.39e-09 | 108 | 44 | 7 | int:SH3RF1 | |
| Interaction | SMAP1 interactions | 6.86e-09 | 67 | 44 | 6 | int:SMAP1 | |
| Interaction | ZNF385C interactions | 8.90e-09 | 33 | 44 | 5 | int:ZNF385C | |
| Interaction | HLX interactions | 1.62e-08 | 37 | 44 | 5 | int:HLX | |
| Interaction | ZCCHC14 interactions | 1.62e-08 | 37 | 44 | 5 | int:ZCCHC14 | |
| Interaction | ANKHD1 interactions | 1.95e-08 | 216 | 44 | 8 | int:ANKHD1 | |
| Interaction | TBX6 interactions | 2.77e-08 | 41 | 44 | 5 | int:TBX6 | |
| Interaction | SAMD11 interactions | 3.55e-08 | 43 | 44 | 5 | int:SAMD11 | |
| Interaction | BICRAL interactions | 3.55e-08 | 43 | 44 | 5 | int:BICRAL | |
| Interaction | SP4 interactions | 5.03e-08 | 46 | 44 | 5 | int:SP4 | |
| Interaction | RBM23 interactions | 5.36e-08 | 94 | 44 | 6 | int:RBM23 | |
| Interaction | KRTAP19-1 interactions | 5.62e-08 | 47 | 44 | 5 | int:KRTAP19-1 | |
| Interaction | KRTAP19-5 interactions | 7.32e-08 | 99 | 44 | 6 | int:KRTAP19-5 | |
| Interaction | OXER1 interactions | 7.73e-08 | 50 | 44 | 5 | int:OXER1 | |
| Interaction | PHF1 interactions | 8.57e-08 | 172 | 44 | 7 | int:PHF1 | |
| Interaction | GTF2A1 interactions | 9.83e-08 | 104 | 44 | 6 | int:GTF2A1 | |
| Interaction | RIPPLY1 interactions | 1.26e-07 | 55 | 44 | 5 | int:RIPPLY1 | |
| Interaction | ZBTB32 interactions | 1.65e-07 | 58 | 44 | 5 | int:ZBTB32 | |
| Interaction | FAM9A interactions | 1.80e-07 | 59 | 44 | 5 | int:FAM9A | |
| Interaction | CABP2 interactions | 2.13e-07 | 61 | 44 | 5 | int:CABP2 | |
| Interaction | C10orf55 interactions | 2.94e-07 | 65 | 44 | 5 | int:C10orf55 | |
| Interaction | TBX3 interactions | 3.98e-07 | 69 | 44 | 5 | int:TBX3 | |
| Interaction | VPS37C interactions | 5.98e-07 | 141 | 44 | 6 | int:VPS37C | |
| Interaction | FAM168A interactions | 6.23e-07 | 142 | 44 | 6 | int:FAM168A | |
| Interaction | ESRP1 interactions | 6.90e-07 | 77 | 44 | 5 | int:ESRP1 | |
| Interaction | LASP1 interactions | 9.93e-07 | 247 | 44 | 7 | int:LASP1 | |
| Interaction | RBPMS2 interactions | 1.00e-06 | 83 | 44 | 5 | int:RBPMS2 | |
| Interaction | PRR35 interactions | 1.00e-06 | 83 | 44 | 5 | int:PRR35 | |
| Interaction | DMRT3 interactions | 1.27e-06 | 87 | 44 | 5 | int:DMRT3 | |
| Interaction | SNRPB interactions | 1.43e-06 | 517 | 44 | 9 | int:SNRPB | |
| Interaction | PRR20B interactions | 1.50e-06 | 90 | 44 | 5 | int:PRR20B | |
| Interaction | PRR20C interactions | 1.50e-06 | 90 | 44 | 5 | int:PRR20C | |
| Interaction | PRR20D interactions | 1.50e-06 | 90 | 44 | 5 | int:PRR20D | |
| Interaction | TIAL1 interactions | 1.91e-06 | 172 | 44 | 6 | int:TIAL1 | |
| Interaction | POU2F1 interactions | 2.11e-06 | 175 | 44 | 6 | int:POU2F1 | |
| Interaction | BANP interactions | 2.13e-06 | 277 | 44 | 7 | int:BANP | |
| Interaction | PRR20E interactions | 2.66e-06 | 101 | 44 | 5 | int:PRR20E | |
| Interaction | TRIM35 interactions | 2.93e-06 | 103 | 44 | 5 | int:TRIM35 | |
| Interaction | TLX3 interactions | 2.95e-06 | 291 | 44 | 7 | int:TLX3 | |
| Interaction | DAZAP2 interactions | 3.01e-06 | 186 | 44 | 6 | int:DAZAP2 | |
| Interaction | RHOXF2 interactions | 3.07e-06 | 104 | 44 | 5 | int:RHOXF2 | |
| Interaction | VEZF1 interactions | 3.22e-06 | 105 | 44 | 5 | int:VEZF1 | |
| Interaction | MAGED1 interactions | 3.23e-06 | 295 | 44 | 7 | int:MAGED1 | |
| Interaction | GLIS2 interactions | 3.38e-06 | 106 | 44 | 5 | int:GLIS2 | |
| Interaction | FOXH1 interactions | 3.87e-06 | 109 | 44 | 5 | int:FOXH1 | |
| Interaction | PRR20A interactions | 3.87e-06 | 109 | 44 | 5 | int:PRR20A | |
| Interaction | ZC3H10 interactions | 4.57e-06 | 200 | 44 | 6 | int:ZC3H10 | |
| Interaction | NOTCH3 interactions | 4.62e-06 | 113 | 44 | 5 | int:NOTCH3 | |
| Interaction | VAC14 interactions | 4.70e-06 | 201 | 44 | 6 | int:VAC14 | |
| Interaction | BHLHE40 interactions | 5.96e-06 | 119 | 44 | 5 | int:BHLHE40 | |
| Interaction | THAP1 interactions | 5.96e-06 | 119 | 44 | 5 | int:THAP1 | |
| Interaction | HYPK interactions | 7.58e-06 | 125 | 44 | 5 | int:HYPK | |
| Interaction | PITX1 interactions | 8.19e-06 | 127 | 44 | 5 | int:PITX1 | |
| Interaction | SIAH1 interactions | 8.53e-06 | 223 | 44 | 6 | int:SIAH1 | |
| Interaction | CCNK interactions | 9.88e-06 | 132 | 44 | 5 | int:CCNK | |
| Interaction | YPEL3 interactions | 1.03e-05 | 133 | 44 | 5 | int:YPEL3 | |
| Interaction | TOLLIP interactions | 1.15e-05 | 358 | 44 | 7 | int:TOLLIP | |
| Interaction | ARID5A interactions | 1.67e-05 | 147 | 44 | 5 | int:ARID5A | |
| Interaction | POU6F2 interactions | 1.72e-05 | 148 | 44 | 5 | int:POU6F2 | |
| Interaction | TFG interactions | 1.95e-05 | 258 | 44 | 6 | int:TFG | |
| Interaction | NCK2 interactions | 2.13e-05 | 262 | 44 | 6 | int:NCK2 | |
| Interaction | PATZ1 interactions | 2.74e-05 | 163 | 44 | 5 | int:PATZ1 | |
| Interaction | DVL3 interactions | 3.09e-05 | 280 | 44 | 6 | int:DVL3 | |
| Interaction | ABI2 interactions | 3.48e-05 | 286 | 44 | 6 | int:ABI2 | |
| Interaction | NFYC interactions | 4.06e-05 | 177 | 44 | 5 | int:NFYC | |
| Interaction | SNRPC interactions | 4.30e-05 | 440 | 44 | 7 | int:SNRPC | |
| Interaction | EIF4ENIF1 interactions | 4.54e-05 | 300 | 44 | 6 | int:EIF4ENIF1 | |
| Interaction | HIVEP1 interactions | 5.15e-05 | 186 | 44 | 5 | int:HIVEP1 | |
| Interaction | RBM42 interactions | 7.83e-05 | 331 | 44 | 6 | int:RBM42 | |
| Interaction | HMGA2 interactions | 2.44e-04 | 140 | 44 | 4 | int:HMGA2 | |
| Interaction | CDH17 interactions | 2.53e-04 | 11 | 44 | 2 | int:CDH17 | |
| Interaction | POGZ interactions | 2.70e-04 | 265 | 44 | 5 | int:POGZ | |
| Interaction | TCF7L2 interactions | 3.78e-04 | 285 | 44 | 5 | int:TCF7L2 | |
| Interaction | CDC37 interactions | 4.55e-04 | 645 | 44 | 7 | int:CDC37 | |
| Interaction | THRB interactions | 7.15e-04 | 186 | 44 | 4 | int:THRB | |
| Interaction | RNF4 interactions | ZNF263 PRR20C PRR20D FBN2 PRR20B UBQLN2 CHERP RRP1B PRR20E PRR20A | 7.60e-04 | 1412 | 44 | 10 | int:RNF4 |
| Interaction | ROR2 interactions | 7.65e-04 | 333 | 44 | 5 | int:ROR2 | |
| Interaction | RBPMS interactions | 8.40e-04 | 340 | 44 | 5 | int:RBPMS | |
| Interaction | SRPK2 interactions | 8.52e-04 | 717 | 44 | 7 | int:SRPK2 | |
| Interaction | PNMA3 interactions | 8.63e-04 | 20 | 44 | 2 | int:PNMA3 | |
| Interaction | CALM3 interactions | 8.74e-04 | 343 | 44 | 5 | int:CALM3 | |
| Interaction | SORBS3 interactions | 9.72e-04 | 202 | 44 | 4 | int:SORBS3 | |
| Interaction | SLC9A8 interactions | 1.35e-03 | 25 | 44 | 2 | int:SLC9A8 | |
| Interaction | MSS51 interactions | 1.35e-03 | 25 | 44 | 2 | int:MSS51 | |
| Cytoband | 4q35.2 | 6.48e-13 | 27 | 55 | 6 | 4q35.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4q35 | 1.54e-12 | 117 | 55 | 8 | chr4q35 | |
| Cytoband | 13q21.1 | 2.62e-12 | 13 | 55 | 5 | 13q21.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr13q21 | 3.10e-07 | 117 | 55 | 5 | chr13q21 | |
| Cytoband | Xp11.21 | 8.17e-04 | 35 | 55 | 2 | Xp11.21 | |
| Cytoband | 19p13.3 | 2.92e-03 | 237 | 55 | 3 | 19p13.3 | |
| GeneFamily | PRD class homeoboxes and pseudogenes | 1.67e-10 | 92 | 31 | 7 | 521 | |
| Disease | obsolete aging, cognition | 1.95e-11 | 15 | 45 | 5 | EFO_0003925, GO_0007568 | |
| Disease | t-tau:beta-amyloid 1-42 ratio measurement | 5.47e-08 | 66 | 45 | 5 | EFO_0007708 | |
| Disease | mosaic loss of chromosome Y measurement | 1.45e-07 | 80 | 45 | 5 | EFO_0007783 | |
| Disease | Tinnitus, wellbeing measurement | 3.62e-07 | 96 | 45 | 5 | EFO_0007869, HP_0000360 | |
| Disease | telomere length | 1.12e-04 | 313 | 45 | 5 | EFO_0004505 | |
| Disease | testosterone measurement | 2.98e-03 | 1275 | 45 | 7 | EFO_0004908 | |
| Disease | Obesity | 3.78e-03 | 205 | 45 | 3 | C0028754 | |
| Disease | coronary artery disease | 9.17e-03 | 1194 | 45 | 6 | EFO_0001645 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| AGSPEPEPAPWQALP | 16 | Q96EY9 | |
| PSQQPDPPWAAPHVV | 66 | A0A096LP49 | |
| AAWEPQAGEAPPPQP | 321 | P0CJ87 | |
| AAWEPQAGAAPPPQP | 321 | P0CJ89 | |
| FDPAWPQPPELPGIN | 461 | Q8WXS8 | |
| NSEPWGLVAPPQPVP | 246 | Q69YU3 | |
| PPQQDWKGPPAASPA | 91 | Q01432 | |
| GLAPLAQPQPPQAAW | 86 | Q6VUC0 | |
| ESLQAWGAPQPPPPQ | 116 | Q7Z5J4 | |
| PQPAWEAPQGQLPAP | 61 | Q9UJ55 | |
| QAPPAQLATPPGWQA | 356 | Q9UJ55 | |
| WQAPPAVLQAQPGPP | 686 | Q9UJ55 | |
| AAWEPQAGAAPPPQP | 321 | Q9UBX2 | |
| PLGNGPPQEPNGPSW | 256 | A0A1B0GTS1 | |
| PQPQPEPSPWGPLDD | 46 | A0A0U1RRL7 | |
| DWDPLDPGVPAPQAP | 556 | Q96Q04 | |
| AAWEPQAGAAPPPQP | 321 | P0CJ86 | |
| PPGLAGAPPPNQSWV | 476 | A8MYZ6 | |
| VPPPWDLGPAAGNPA | 36 | P12525 | |
| APPGQQAPPNTDWRF | 806 | Q9UN70 | |
| PLGNGPPQEPNGPSW | 256 | A0A1B0GWH4 | |
| PPAAPGPQAVDWQPV | 166 | P86480 | |
| QVPVPPGWNQLPSGA | 311 | Q14686 | |
| PPAAPGPQAVDWQPV | 166 | P86496 | |
| PPAAPGPQAVDWQPV | 166 | P86481 | |
| HPVAPWGQQQPPEQP | 426 | Q8IWX8 | |
| PFWERPPQDPNAPGA | 101 | Q8NCL4 | |
| AAWEPQAGAAPPPQP | 321 | Q6RFH8 | |
| AAWEPQAGAAPPPQP | 321 | P0CJ90 | |
| GPAPWEAPEPPQPQR | 131 | Q96A59 | |
| IPISWNAPQAPPGPG | 296 | Q00978 | |
| LWAQGTAGQPQPPPP | 21 | P35556 | |
| AAWEPQAGAAPPPQP | 321 | P0CJ88 | |
| PFWDSPPANPFQGGP | 811 | Q16584 | |
| PNGPPWNPGSLQPQH | 61 | Q5VUJ6 | |
| PPAAREWNLPPNAPA | 11 | Q9BQA1 | |
| SPNPPAWVRPDNEAP | 651 | Q8N4C8 | |
| ASARPPPPQGAQVWP | 401 | O60391 | |
| PPSWTDPPQPGAEEA | 646 | Q9NRF2 | |
| AWPPLQQEGPPTGPA | 541 | Q14684 | |
| PPAAPGPQAVDWQPV | 166 | P86479 | |
| PPAAPGPQAVDWQPV | 166 | P86478 | |
| WEPEPDAPSQPGPAL | 46 | O75783 | |
| PAWEQQEEPPAPNPP | 1021 | Q0VD83 | |
| PPHAWEPGAAPAQQP | 191 | P98169 | |
| PQDVPPHAPPDWAQP | 551 | Q9UPR6 | |
| SEQPWPQPVPALAPG | 1136 | O15027 | |
| WQPPGPPIQHSPADQ | 51 | A0A1W2PR48 | |
| WPQGPPPWRQAAPFA | 76 | Q96G79 | |
| APVAHPAPGGPEEQW | 486 | Q96KM6 | |
| PPPHAWEPGAAPAQQ | 186 | P98168 | |
| GQQVPASPQGPAVPW | 136 | Q8NF99 | |
| QAAGPPEWPPGSPQA | 26 | Q6ICL7 | |
| ENRDPLPNPWAPPPA | 311 | Q9UHD9 | |
| RPDDPWPAGPQPPEN | 96 | Q9UIG4 | |
| QPPENPWPPAPEVDN | 106 | Q9UIG4 | |
| DCAWSQELPPPDPGP | 21 | O14978 | |
| AAWEPQAGAAPPPQP | 321 | P0CJ85 |