Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

4.17e-053752GO:0008332
GeneOntologyMolecularFunctioncalcium-dependent ATPase activity

ATP2A1 ATP2A3

8.31e-054752GO:0030899
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZBTB7A JUND KMT2D NFATC2 EGR4 TBX21 HAND1 RELB SKI ZBTB3 CASZ1 TBX2 TBX6 NKX1-2

6.95e-0414127514GO:0000981
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2A1 ATP2A3

7.49e-0411752GO:0005388
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

JUND KMT2D NFATC2 EGR4 TBX21 HAND1 RELB CASZ1

1.18e-03560758GO:0001228
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1H CACNA1G

1.23e-0314752GO:0008331
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

JUND KMT2D NFATC2 EGR4 TBX21 HAND1 RELB CASZ1

1.26e-03566758GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZBTB7A NFATC2 TBX21 HAND1 SKI TBX2

1.29e-03320756GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZBTB7A NFATC2 TBX21 HAND1 SKI TBX2

1.41e-03326756GO:0001217
GeneOntologyMolecularFunctionubiquitin protein ligase binding

TANK MFHAS1 RNF8 SCAMP3 TNFRSF1B SKI

1.67e-03337756GO:0031625
GeneOntologyBiologicalProcessdetermination of heart left/right asymmetry

MMP21 HAND1 RNF207 TBX2 TBX6

9.50e-0679745GO:0061371
GeneOntologyBiologicalProcessregulation of heart looping

RNF207 TBX2

1.27e-052742GO:1901207
GeneOntologyBiologicalProcesspositive regulation of cardiac muscle cell contraction

CACNA1H ATP2A1

3.80e-053742GO:0106134
GeneOntologyBiologicalProcessheart development

ACAN FGF2 MMP21 HAND1 CACNA1G TNFRSF1B SKI RNF207 ALPK2 TBX2 TBX6

7.68e-057577411GO:0007507
GeneOntologyBiologicalProcessheart looping

HAND1 RNF207 TBX2 TBX6

1.38e-0473744GO:0001947
GeneOntologyBiologicalProcesspositive regulation of actin filament-based movement

CACNA1H ATP2A1

1.89e-046742GO:1903116
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

HAND1 RNF207 TBX2 TBX6

1.96e-0480744GO:0003143
GeneOntologyBiologicalProcessdetermination of left/right symmetry

MMP21 HAND1 RNF207 TBX2 TBX6

2.31e-04154745GO:0007368
GeneOntologyBiologicalProcesscartilage development

ZBTB7A NFATC2 ACAN FGF2 HAND1 GNAS

2.39e-04243746GO:0051216
GeneOntologyBiologicalProcessregulation of heart contraction

CACNA1H CACNA1G ATP2A1 ATP2A3 RNF207 TBX2

2.72e-04249746GO:0008016
GeneOntologyBiologicalProcessleft/right pattern formation

MMP21 HAND1 RNF207 TBX2 TBX6

2.92e-04162745GO:0060972
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

MMP21 HAND1 RNF207 TBX2 TBX6

3.18e-04165745GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

MMP21 HAND1 RNF207 TBX2 TBX6

3.18e-04165745GO:0009799
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1H CACNA1G ATP2A1 RNF207

3.50e-0493744GO:0086003
GeneOntologyCellularComponenttranscription factor AP-1 complex

JUND NFATC2

1.19e-045732GO:0035976
GeneOntologyCellularComponentplatelet dense tubular network membrane

ATP2A1 ATP2A3

4.26e-049732GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ATP2A1 ATP2A3

6.48e-0411732GO:0031094
Domainp53-like_TF_DNA-bd

NFATC2 TBX21 RELB TBX2 TBX6

1.60e-0653705IPR008967
DomainTF_T-box

TBX21 TBX2 TBX6

3.30e-0517703IPR001699
DomainTBOX

TBX21 TBX2 TBX6

3.30e-0517703SM00425
DomainTF_T-box_CS

TBX21 TBX2 TBX6

3.30e-0517703IPR018186
Domain-

TBX21 TBX2 TBX6

3.30e-05177032.60.40.820
DomainTBOX_3

TBX21 TBX2 TBX6

3.30e-0517703PS50252
DomainT-box

TBX21 TBX2 TBX6

3.30e-0517703PF00907
DomainTBOX_1

TBX21 TBX2 TBX6

3.30e-0517703PS01283
DomainTBOX_2

TBX21 TBX2 TBX6

3.30e-0517703PS01264
DomainVDCC_T_a1

CACNA1H CACNA1G

4.14e-053702IPR005445
DomainP-type_ATPase_IIA

ATP2A1 ATP2A3

4.14e-053702IPR005782
DomainTF_Brachyury

TBX2 TBX6

2.06e-046702IPR002070
DomainRHD_dimer

NFATC2 RELB

6.11e-0410702IPR032397
DomainRHD_dimer

NFATC2 RELB

6.11e-0410702PF16179
DomainNFkB/Dor

NFATC2 RELB

6.11e-0410702IPR000451
DomainREL_1

NFATC2 RELB

6.11e-0410702PS01204
DomainRHD_DNA_bind_dom

NFATC2 RELB

6.11e-0410702IPR011539
DomainRHD_DNA_bind

NFATC2 RELB

6.11e-0410702PF00554
DomainHydrolase_3

ATP2A1 ATP2A3

6.11e-0410702PF08282
DomainREL_2

NFATC2 RELB

6.11e-0410702PS50254
DomainVDCCAlpha1

CACNA1H CACNA1G

6.11e-0410702IPR002077
Domain-

NFATC2 RELB

6.11e-04107022.60.40.340
Domain-

ATP2A1 ATP2A3

1.61e-03167021.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2A1 ATP2A3

1.61e-0316702IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP2A1 ATP2A3

1.82e-0317702IPR006068
DomainCation_ATPase_C

ATP2A1 ATP2A3

1.82e-0317702PF00689
DomainPDZ

FRMPD4 SIPA1L3 RGS3 PDZRN3

1.94e-03141704PF00595
DomainCation_ATPase_N

ATP2A1 ATP2A3

2.04e-0318702PF00690
DomainCation_ATPase_N

ATP2A1 ATP2A3

2.04e-0318702SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2A1 ATP2A3

2.27e-0319702IPR004014
DomainPDZ

FRMPD4 SIPA1L3 RGS3 PDZRN3

2.31e-03148704SM00228
Domain-

FRMPD4 SIPA1L3 RGS3 PDZRN3

2.43e-031507042.30.42.10
DomainPDZ

FRMPD4 SIPA1L3 RGS3 PDZRN3

2.49e-03151704PS50106
DomainPDZ

FRMPD4 SIPA1L3 RGS3 PDZRN3

2.55e-03152704IPR001478
DomainIPT

NFATC2 RELB

4.57e-0327702SM00429
DomainFHA

TCF19 RNF8

4.91e-0328702SM00240
DomainTIG

NFATC2 RELB

6.00e-0331702PF01833
DomainFHA_DOMAIN

TCF19 RNF8

6.00e-0331702PS50006
DomainFHA

TCF19 RNF8

6.00e-0331702PF00498
DomainIPT

NFATC2 RELB

6.39e-0332702IPR002909
Domain-

ATP2A1 ATP2A3

6.39e-03327023.40.1110.10
Domain-

ATP2A1 ATP2A3

6.39e-03327022.70.150.10
Domain-

KMT2D TCF19 RNF8 FGD1 RNF207 PDZRN3

6.69e-034497063.30.40.10
DomainZnf_RING/FYVE/PHD

KMT2D TCF19 RNF8 FGD1 RNF207 PDZRN3

7.43e-03459706IPR013083
DomainATPase_P-typ_cyto_domN

ATP2A1 ATP2A3

7.61e-0335702IPR023299
DomainFHA_dom

TCF19 RNF8

8.03e-0336702IPR000253
DomainP_typ_ATPase

ATP2A1 ATP2A3

8.03e-0336702IPR001757
DomainATPase_P-typ_P_site

ATP2A1 ATP2A3

8.03e-0336702IPR018303
DomainATPASE_E1_E2

ATP2A1 ATP2A3

8.03e-0336702PS00154
Domain-

TCF19 RNF8

8.03e-03367022.60.200.20
DomainZINC_FINGER_C2H2_2

ZBTB7A ZNF469 TANK SLC2A4RG EGR4 ZBTB3 CASZ1 ZNF541

8.27e-03775708PS50157
DomainZINC_FINGER_C2H2_1

ZBTB7A ZNF469 TANK SLC2A4RG EGR4 ZBTB3 CASZ1 ZNF541

8.39e-03777708PS00028
DomainATPase_P-typ_transduc_dom_A

ATP2A1 ATP2A3

8.47e-0337702IPR008250
DomainE1-E2_ATPase

ATP2A1 ATP2A3

8.47e-0337702PF00122
DomainZnf_C2H2

ZBTB7A ZNF469 TANK SLC2A4RG EGR4 ZBTB3 CASZ1 ZNF541

1.03e-02805708IPR007087
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

JUND KMT2D AATK SLC2A4RG GAREM2 KIF26A MFHAS1 SIPA1L3 CACNA1H RELB MAPKBP1 MBD6 ATP2A3 GCN1 PLEKHG5 CASZ1

1.75e-091105761635748872
Pubmed

Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8+ T cells.

TBX21 TBX2 TBX6

1.00e-07576310970091
Pubmed

Intracellular calcium plays an essential role in cardiac development.

HAND1 CACNA1H CACNA1G

5.57e-07876312761855
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

ACAN CACNA1H CACNA1G

1.19e-061076324778262
Pubmed

A census of human transcription factors: function, expression and evolution.

ZBTB7A JUND KMT2D NFATC2 TBX21 HAND1 RELB SKI ZNF541 TBX2 TBX6

4.41e-06908761119274049
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

4.71e-06276214988077
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

4.71e-06276221622683
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

4.71e-06276220685979
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

4.71e-06276222469755
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

4.71e-06276223436820
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

4.71e-06276221079360
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

4.71e-06276231042060
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

4.71e-06276222886848
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

4.71e-06276229082441
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

4.71e-06276222574369
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

4.71e-06276221438841
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

4.71e-06276222808078
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

1.41e-05376224327205
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

1.41e-05376223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

1.41e-05376224966091
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

1.41e-05376226488564
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

1.41e-05376218591418
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

1.41e-05376211230107
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

1.41e-05376228846697
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

1.41e-05376221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

1.41e-05376233547341
Pubmed

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression.

NFATC2 TBX21

1.41e-05376215684054
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

1.41e-05376228972185
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

1.41e-05376211927664
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

1.41e-05376222572848
Pubmed

The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.

ATP2A1 ATP2A3

1.41e-05376216410239
Pubmed

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

NFATC2 TBX21

1.41e-05376217082665
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

1.41e-05376231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

1.41e-05376225825486
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1H CACNA1G

1.41e-05376211897840
Pubmed

Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family.

AATK LMTK3

1.41e-05376217651901
Pubmed

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

CACNA1H CACNA1G

1.41e-05376237739992
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

SPATA2L SPNS1 AATK PPP1R3F CACNA1H GNAS SLC25A28 ATP2A1 TCTN2

2.13e-0569776928298427
Pubmed

Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet.

NFATC2 TBX21

2.82e-05476223616576
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1H CACNA1G

2.82e-05476231800012
Pubmed

NFAT restricts osteochondroma formation from entheseal progenitors.

NFATC2 ACAN

2.82e-05476227158674
Pubmed

T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3.

NFATC2 TBX21

2.82e-05476217986443
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1H CACNA1G

2.82e-05476228165634
Pubmed

The nongastric H+-K+-ATPases: molecular and functional properties.

ATP2A1 ATP2A3

2.82e-05476210362770
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1H CACNA1G

2.82e-05476221788606
Pubmed

Suppression of the human immunodeficiency virus long terminal repeat by CD8+ T cells is dependent on the NFAT-1 element.

NFATC2 RELB

2.82e-0547628834464
Pubmed

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

ATP2A1 ATP2A3

2.82e-05476225110346
Pubmed

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

CACNA1H CACNA1G

2.82e-05476228655554
Pubmed

Lineage tracing of axial progenitors using Nkx1-2CreERT2 mice defines their trunk and tail contributions.

TBX6 NKX1-2

4.69e-05576230201686
Pubmed

The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin.

RGS3 PDZRN3

4.69e-05576215458844
Pubmed

Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.

NFATC2 EGR4

4.69e-05576212560487
Pubmed

Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene.

NFATC2 GNAS

4.69e-0557628973343
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1H CACNA1G

4.69e-05576212060068
Pubmed

Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1.

NFATC2 RELB

4.69e-05576210207088
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

CACNA1H CACNA1G

4.69e-05576229720258
Pubmed

Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.

AMBN CACNA1G RGS3

4.75e-053276319320717
Pubmed

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.

TBX21 TBX2 TBX6

5.22e-053376318356246
Pubmed

Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth.

ACAN FGF2

7.03e-05676231371388
Pubmed

IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice.

GNAS TNFRSF1B

7.03e-05676226456334
Pubmed

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality.

RELB TNFRSF1B

7.03e-05676210077625
Pubmed

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

TANK TNFRSF1B

7.03e-0567628710854
Pubmed

Evolution of mouse T-box genes by tandem duplication and cluster dispersion.

TBX2 TBX6

7.03e-0567628878690
Pubmed

NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.

RELB TNFRSF1B

7.03e-05676224892805
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1G ATP2A1 ATP2A3

8.01e-053876330786075
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1H CACNA1G

9.83e-05776212900400
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

ATP2A1 ATP2A3

9.83e-05776224786561
Pubmed

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.

KMT2D RELB

9.83e-05776219219072
Pubmed

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.

TANK TNFRSF1B

9.83e-05776219262425
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

JUND KMT2D GTF3C1 NFATC2 HAND1 RELB SKI CASZ1 TBX2

1.05e-0485776925609649
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

JUND TCF19 GTF3C1 TBX21 HAND1 RELB SKI ZBTB3 TBX2

1.25e-0487776920211142
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2A1 ATP2A3

1.31e-04876210951186
Pubmed

Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants.

TBX21 TNFRSF1B

1.31e-04876230635238
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

ATP2A1 ATP2A3

1.31e-04876219033399
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1H CACNA1G

1.31e-04876228330839
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H CACNA1G

1.31e-04876234478646
Pubmed

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.

TNFRSF1B SKI

1.31e-0487628405064
Pubmed

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

ATP2A1 ATP2A3

1.31e-04876227923914
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

AMBN ZBTB7A ZNF469 PSD MMP21 DGKE SKI PDZRN3 TCTN2 TBX2

1.56e-041116761031753913
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

JUND GTF3C1 NFATC2 TBX21 HAND1 RELB ZBTB3 NKX1-2

1.60e-0470976822988430
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KIF26A PPP1R3F LMTK3 RGS3 CASZ1

1.62e-0423376537704626
Pubmed

Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development.

JUND HAND1

1.68e-0497627671815
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1H CACNA1G

1.68e-04976216382099
Pubmed

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

ATP2A1 ATP2A3

1.68e-04976225640239
Pubmed

Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state.

RELB TNFRSF1B

1.68e-04976231959883
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

ZBTB7A JUND NFATC2 EGR4 TBX21 TBX2 TBX6

1.90e-0454476728473536
Pubmed

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

TNFRSF1B SKI

2.10e-04107621645445
Pubmed

Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression.

NFATC2 TBX21

2.10e-041076215728489
Pubmed

Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.

ACAN FAM181B CASZ1

2.42e-045576329997285
Pubmed

Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.

HAND1 TBX2

2.56e-041176220824138
Pubmed

The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.

HAND1 TBX2

2.56e-041176220139090
Pubmed

The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis.

HAND1 ATP2A1

2.56e-041176212122109
Pubmed

Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation.

TBX2 TBX6

2.56e-04117628954725
Pubmed

Periostin as a biomarker of the amniotic membrane.

HAND1 TBX2

2.56e-041176222966238
Pubmed

Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.

ACAN FGF2

2.56e-041176228323137
Pubmed

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.

TANK PSD RELB TNFRSF1B PLEKHG5

2.84e-0426376519773279
Pubmed

Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2.

HAND1 TBX2

3.07e-041276217259303
Pubmed

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.

TBX21 TNFRSF1B

3.07e-041276229436413
Pubmed

Expression of Slit and Robo genes in the developing mouse heart.

HAND1 TBX2

3.62e-041376220941780
Pubmed

Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.

ACAN TCTN2

3.62e-041376232909945
Pubmed

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.

HAND1 TBX6

4.22e-041476210837126
InteractionTOP3B interactions

JUND KMT2D AATK SLC2A4RG GAREM2 KIF26A MFHAS1 SIPA1L3 CACNA1H RELB GNAS MAPKBP1 MBD6 ATP2A3 GCN1 PLEKHG5 CASZ1

1.01e-0514707117int:TOP3B
Cytoband1p36.31

PLEKHG5 RNF207

2.43e-04147621p36.31
Cytoband19q13.33

SYT3 LMTK3 ZNF541

7.44e-0410676319q13.33
Cytoband1p36.22

TNFRSF1B CASZ1

1.73e-03377621p36.22
Cytoband10q26.13

MMP21 NKX1-2

1.83e-033876210q26.13
Cytoband17q22

DGKE CACNA1G

2.45e-034476217q22
GeneFamilyT-boxes

TBX21 TBX2 TBX6

2.47e-0518583766
GeneFamilyATPases Ca2+ transporting

ATP2A1 ATP2A3

3.59e-0495821209
GeneFamilyPDZ domain containing

FRMPD4 SIPA1L3 RGS3 PDZRN3

1.43e-031525841220
GeneFamilyCalcium voltage-gated channel subunits

CACNA1H CACNA1G

3.13e-0326582253
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

KIF26A ACAN GPRIN3 CACNA1H SLC25A28 ATP2A3

1.11e-0619776698f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

SPATA2L ATP2A3 PLEKHG5 RAB44 RGS3

7.81e-061597659f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRIN3 CACNA1H ADARB2 RAB44 TBX6

8.05e-06160765f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellParenchymal-10x3prime_v2-Hematologic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GAREM2 NFATC2 RNF207

1.04e-05257637b267cdcb6afcf603d566c4d5268eb44eacf47b6
ToppCellParenchymal-10x3prime_v2-Hematologic-Erythrocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GAREM2 NFATC2 RNF207

1.04e-0525763096ca30d9277cfd9cb2501c40b085cc358cb628b
ToppCellParenchymal-10x3prime_v2-Hematologic-Erythrocyte-Erythrocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GAREM2 NFATC2 RNF207

1.04e-05257633d7b43ecf6ae64996d91765c50f614742e18bd25
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26A CMPK2 FGF2 ATP2A3 RGS3

1.05e-05169765c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellControl-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

ZBTB7A CMPK2 GPRIN3 RELB SKI

1.08e-051707659e328e1f904c77dcce8aee4df775d7f0ac725775
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-Activated_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TBX21 RELB TNFRSF1B RGS3 ILKAP

1.35e-051787655b19dbf9dc8e41e6a16a2abbb798d49ee8d8653f
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CBY3 ATP2A3 TBX2 TBX6

1.37e-05857647c5ea38893372fdecf7cc3ccf46a37b4ec45f0b1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CBY3 ATP2A3 TBX2 TBX6

1.37e-05857645a2c02aeceeabd44a417b09ac8b2e2f185070b15
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CBY3 ATP2A3 TBX2 TBX6

1.37e-05857640bfabb6761a84d6a04f9fa415106a33059d78099
ToppCellControl-Classical_Monocyte-cMono_4|Control / Disease condition and Cell class

ZBTB7A CMPK2 GPRIN3 RELB SKI

1.46e-05181765f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A HEATR5B CCDC171 ATP2A3 RGS3

1.46e-05181765709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

JUND GPRIN3 GNAS MAPKBP1 RNF207

1.71e-051877650099def970fbc828756fbf853eca2ce77b8cd342
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

AMBN JUND GNAS ADARB2 PDZRN3

1.85e-05190765842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF26B CACNA1H ADARB2 PDZRN3 TBX2

2.04e-051947652d66091097e106c7bee22e5281f50724700bdf8d
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

MAPK4 RGS3 PDZRN3 CASZ1 ALPK2

2.04e-05194765c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

ACAN CACNA1H ADARB2 PDZRN3 TBX2

2.04e-051947655e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NFATC2 TBX21 ATP2A3 PDZRN3 TBX2

2.09e-05195765e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 NFATC2 TBX21 TNFRSF1B CASZ1

2.20e-05197765f84263c5aaf3a5cd46d6e06358e8de6c6e6eaa3b
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PPP1R3F ATP2A3 TBX2 TBX6

2.82e-051027648c4d9483ff983538593f4e17f4a74a93cdda59c4
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PPP1R3F ATP2A3 TBX2 TBX6

2.82e-0510276472ce247dad7404e6b9c971b5c29d3c6846da5efc
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PPP1R3F ATP2A3 TBX2 TBX6

2.82e-051027645feedce6d26a578c4aaba4e4824b3d0c3f3806bc
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIF26A EGR4 CACNA1H CASZ1

9.95e-0514176440ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26A KIF26B CASZ1 TBX2

1.30e-0415176410da94037225a71844281ddcb395072250a78094
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JUND PSD ACAN GNAS

1.36e-0415376461fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCellmild_COVID-19_(asymptomatic)-MAIT|World / disease group, cell group and cell class (v2)

GTF3C1 GPRIN3 SLC41A1 ATP2A1

1.36e-041537642b4c69f6db17927d6506a645ac058133e60b0103
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF19 GAREM2 NFATC2 TBX21

1.58e-041597642233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF19 TBX21 TNFRSF1B RAB44

1.62e-0416076497c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GTF3C1 TBX21 PLEKHG5 RGS3

1.62e-04160764955acb023ce4ccfac5073c9d693db87db3856187
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SYT3 NFATC2 ACAN CACNA1G

1.66e-041617649703b7e67d9fadb6129cad166bd01be915042e44
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

CMPK2 FGF2 FAM181B TBX2

1.78e-04164764362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

ZNF469 EGR4 KIF26B ACAN

1.78e-041647649b4a6007abae992db871d9f6f731d5af724de30d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DGKE RELB TNFRSF1B RGS3

1.86e-041667648e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD4 RELB MAPKBP1 TBX6

1.86e-0416676443f84d3cd58e93ce00c241656c4cba27604b4932
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-9|TCGA-Colorectal / Sample_Type by Project: Shred V9

PSD FRMPD4 HAND1 MAPK4

1.86e-0416676468e6fc7c0040bbe48a93f96ecf28afffdc626845
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM1 PSD MAPK4 RAB44

1.91e-041677642812353ff66e76f10bd327ceb0e6b009502a5258
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 SIPA1L3 LMTK3 ADARB2

1.91e-041677649efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM1 PSD MAPK4 RAB44

1.91e-04167764d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 SIPA1L3 LMTK3 ADARB2

1.91e-04167764904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELB TNFRSF1B ATP2A3 RAB44

1.95e-04168764e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

KIF26A GPRIN3 ATP2A3 PDZRN3

2.00e-04169764e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANK PSD RELB ALPK2

2.04e-04170764df1a34a69ae404c56f00751a01f52359535f5469
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1H ADARB2 PDZRN3 TBX2

2.14e-04172764858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

JUND PDZRN3 ZNF541 TCTN2

2.14e-0417276420ea9db009370aa6235365ce93e153eb5b28db94
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CMPK2 ATP2A1 ATP2A3 RAB44

2.18e-04173764a85cead231e03945fabbc7762540ad21fe4299df
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KIF26A ATP2A3 RGS3 CASZ1

2.23e-04174764b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 FRMPD4 GAREM2 DGKE

2.23e-041747646b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SHROOM1 SIPA1L3 TCTN2 TBX6

2.33e-04176764dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NFATC2 EGR4 TBX21 TNFRSF1B

2.38e-0417776484930899eb2978598bc8a351cbcd9e714e46799d
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRMPD4 KIF26A RGS3 TBX2

2.43e-041787648f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSD FGF2 HAND1 RNF207

2.43e-041787640fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANK PSD RELB ALPK2

2.43e-041787640b456ac768e026c3ecd5a9a4f43d6f126e7685a1
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 AATK NFATC2 CMPK2

2.43e-041787646bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

EGR4 CACNA1H ADARB2 PDZRN3

2.49e-04179764988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

KIF26A ACAN CACNA1H TBX2

2.54e-041807647085a851807e6a833965e1366946db0bbc5174e2
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK GAREM2 CACNA1G TBX2

2.54e-0418076478fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PSD FRMPD4 KIF26B RNF207

2.59e-041817647e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|normal_Lung / Location, Cell class and cell subclass

SCARF1 GAREM2 CACNA1G ALPK2

2.59e-04181764b55dbcfae8c92d322071906831489830a22239b9
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 GPRIN3 DGKE RGS3

2.59e-041817649bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 KIF26A KIF26B CCDC171

2.59e-041817647af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 KIF26B CASZ1 TBX2

2.65e-04182764fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

SCARF1 GAREM2 CACNA1G ALPK2

2.65e-041827648dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

FGF2 CACNA1H PDZRN3 TBX2

2.70e-04183764d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

GAREM2 ACAN CACNA1H TBX2

2.70e-041837644617b18da8d699a44e4c47980197b1e7eb951470
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF26B ATP2A3 ADARB2 CASZ1

2.70e-04183764e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TBX21 FGF2 PPP1R3F TNFRSF1B

2.70e-04183764278064c9f0582463b83bf156d34e77f60187613b
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFATC2 GNAS OSGIN1 ILKAP

2.70e-041837647534587fa35837c0aaca93c542f2eee493eba637
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 GNAS MAPK4 CASZ1

2.76e-041847648fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRMPD4 CACNA1H ADARB2 TBX2

2.82e-04185764a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A DGKE SLC41A1 TBX2

2.82e-0418576460206c7322b4ddb2010040aac70561df842c9843
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NFATC2 TBX21 CMPK2 ATP2A3

2.82e-04185764191d7e9b34bd1598cb4c18e0cb3d018bad83c757
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SHROOM1 AATK RNF8 FGF2

2.82e-04185764b57dae20c21f984edd2acee4344d86f033108ebf
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NFATC2 TBX21 CMPK2 ATP2A3

2.82e-0418576499fe59c15c3c0f7afa7e182255e4bacfba346132
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANK RELB TNFRSF1B SLC25A28

2.82e-04185764a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SHROOM1 AATK RNF8 FGF2

2.82e-04185764d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRMPD4 CACNA1H ADARB2 TBX2

2.94e-04187764fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

KIF26B CACNA1H PDZRN3 TBX2

2.94e-04187764464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SLC41A1 PDZRN3 CASZ1 ALPK2

2.94e-0418776478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRMPD4 CACNA1H ADARB2 TBX2

2.94e-04187764a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MAPK4 RGS3 CASZ1 ALPK2

3.00e-041887646d249fe92d51a19da19ec14bb2262d394255d577
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

ACAN CACNA1H PDZRN3 TBX2

3.00e-04188764b66264e8f8d536ed2beec31e6746c687718f239b
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 KIF26B CASZ1 TBX2

3.00e-04188764315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

ACAN CACNA1H PDZRN3 TBX2

3.00e-04188764e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellMesenchymal_cells-Myofibroblasts|Mesenchymal_cells / Lineage and Cell class

JUND NFATC2 GNAS OSGIN1

3.06e-04189764f5322429963257cfd3fd813d7b7d273d3d12d622
ToppCellfacs-Limb_Muscle|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND NFATC2 RELB SLC41A1

3.06e-0418976421ec43859d21ffc565acbe36489da1d2d0f9877d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

RNF207 PDZRN3 CASZ1 ALPK2

3.06e-041897645e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSD FRMPD4 HAND1 CACNA1H

3.06e-04189764f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCellNS-critical-d_16-33-Lymphoid-CTL|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC2A4RG NFATC2 TBX21 GPRIN3

3.06e-041897648a02c40bfc92cee37c4dee7c7bf98ab826f64a14
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADARB2 RGS3 PDZRN3 TBX2

3.06e-041897649c2492c38f27e4c699b40680652e4c64911cce52
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

FRMPD4 CACNA1H ADARB2 TBX2

3.06e-04189764d7ed96add29f219183c802895fbff519b627f635
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 KIF26B CASZ1 TBX2

3.12e-04190764c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 KIF26B CASZ1 TBX2

3.12e-041907644836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAN CACNA1H PDZRN3 TBX2

3.12e-0419076473d94fbae92029745989a8712eed8b99fd84c193
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 KIF26B CASZ1 TBX2

3.12e-04190764d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

RNF207 PDZRN3 CASZ1 ALPK2

3.12e-04190764fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellCOVID-19-kidney-T-cells-2|kidney / Disease (COVID-19 only), tissue and cell type

NFATC2 GPRIN3 DGKE ATP2A3

3.18e-04191764698e6a28276704f8baa082d028db2345b973c4bc
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHROOM1 MFHAS1 CMPK2 GPRIN3

3.18e-041917646e1d00404d795ec7cf60f685e42e4ad9a16ac596
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFATC2 TBX21 GPRIN3 ATP2A3

3.18e-0419176496a7179a845d3daa046ed71fa45c51255f130a7f
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

ZBTB7A SPATA2L DGKE MAPKBP1 RGS3 TCTN2 OSGIN1

2.93e-061917475567_DN
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

3.12e-053742CID010679219
DrugAC1L42OX

ACAN FGF2 TNFRSF1B

3.61e-0520743CID000177347
DrugNSC759576

AMBN FGF2 DGKE CACNA1H CACNA1G RELB

3.72e-05191746CID000003075
DrugProguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

ZBTB7A JUND SIPA1L3 SKI ATP2A3 CASZ1

3.83e-051927463505_DN
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A

GTF3C1 FGD1 RELB ATP2A3 PDZRN3 CASZ1

4.06e-051947462221_DN
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

SPATA2L AATK EGR4 SIPA1L3 FGF2 RELB

4.17e-051957467255_UP
DrugBenzthiazide [91-33-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ZBTB7A FGD1 CACNA1H RELB ATP2A3 OSGIN1

4.29e-051967463329_DN
DrugMethimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A

KMT2D TBX21 CCNP HAND1 CACNA1G ATP2A1

4.42e-051977463815_UP
DrugMinaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

KIF26B ACAN RNF8 CACNA1G ATP2A3 TBX6

4.54e-051987464230_UP
DrugDemeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A

AATK ACAN SIPA1L3 FGD1 GNAS OSGIN1

4.67e-051997464728_UP
DiseaseBrody myopathy (implicated_via_orthology)

ATP2A1 ATP2A3

1.96e-053762DOID:0050692 (implicated_via_orthology)
Diseasebladder disease (biomarker_via_orthology)

FGF2 RGS3

6.51e-055762DOID:365 (biomarker_via_orthology)
Diseasecomparative body size at age 10, self-reported

AATK MFHAS1 ACAN GNAS SLC41A1 CCDC171 GCN1

1.06e-04420767EFO_0009819
DiseaseCalcium channel blocker use measurement

NFATC2 MFHAS1 GNAS CASZ1 TBX2

2.28e-04213765EFO_0009930
DiseaseParkinsonism (is_implicated_in)

FGF2 TNFRSF1B

3.55e-0411762DOID:0080855 (is_implicated_in)
Diseaseelectrocardiography

MFHAS1 HAND1 CACNA1G SLC41A1 RNF207 PDZRN3 CASZ1

4.35e-04530767EFO_0004327
Diseaseglycochenodeoxycholate glucuronide (1) measurement

CACNA1G SLC25A28

5.01e-0413762EFO_0800474
Diseasecolon carcinoma (is_marker_for)

KMT2D TNFRSF1B

5.01e-0413762DOID:1520 (is_marker_for)
DiseaseAntihypertensive use measurement

NFATC2 CACNA1H MAPK4 CASZ1 TBX2

6.18e-04265765EFO_0009927
DiseaseSezary Syndrome

KMT2D TNFRSF1B

2.20e-0327762C0036920
DiseaseLiver Cirrhosis

JUND FGF2 TNFRSF1B

2.41e-03103763C0023890
DiseaseStrabismus

ADARB2 RGS3

2.54e-0329762HP_0000486
DiseaseFibrosis, Liver

JUND FGF2 TNFRSF1B

2.55e-03105763C0239946

Protein segments in the cluster

PeptideGeneStartEntry
GPSLPGLDFADPQGS

AMBN

201

Q9NP70
PAFSEPAGEESPFTG

ALPK2

671

Q86TB3
AEAEGSPAAEPSPFL

CASZ1

976

Q86V15
LALGDAGDPGPPDAA

CASZ1

1641

Q86V15
APLPADTTGIGDFLP

CCDC171

1266

Q6TFL3
PSAFPSGLGSELEPS

FAM220BP

166

B1ANY3
DAEPSSAAVPDGFPA

CCNP

36

Q9H8S5
PDLGDAAPPGSPSSF

CBY3

11

A6NI87
GLPATALGFNPPDLD

ATP2A1

801

O14983
GLPATALGFNPPDLD

ATP2A3

801

Q93084
YPSGPLDAGKSDPES

PDZRN3

666

Q9UPQ7
QAASPEEAPLPGLFG

RAB44

351

Q7Z6P3
PGPGTDFTSDQADFP

ADARB2

206

Q9NS39
SGDLLAATGDPPAAP

RGS3

836

P49796
LPDPDFFSGTVSLPG

RELB

461

Q01201
LEPPGGPDLLDDGFA

RELB

476

Q01201
PAPIGELAPGSFLAA

ABHD14B

81

Q96IU4
ASLSGEPPGRFGEPD

NFATC2

76

Q13469
EPFSGLGDLSPLLFP

MBD6

651

Q96DN6
PGAGADALESPASPQ

MFHAS1

41

Q9Y4C4
PAPVDGGASPQFDLD

MAPK4

526

P31152
AAFPAGLPDEPSGKT

KIF26B

1631

Q2KJY2
DGAPSAAPPDGLLAS

JUND

76

P17535
FPLLDGFPGADPDDV

LMTK3

451

Q96Q04
SEGFPGIPSPLDTAF

MMP21

441

Q8N119
DPDSGPDYEALPAGA

SLC25A28

56

Q96A46
PRFSPDSLAGLDPGG

KIF26A

1131

Q9ULI4
DSLAGLDPGGPPALD

KIF26A

1136

Q9ULI4
LLSPADAAPDFPAGG

HAND1

46

O96004
GEPGAAPLSAPAFSL

GCN1

966

Q92616
ILGLAPFPGPEAAAS

EGR4

211

Q05215
SPLYPAAADSPGGED

FAM181B

351

A6NEQ2
VDLGSGPPSGLPDFS

ACAN

1636

P16112
DGPAALAGFPEAVPA

MEIS3P2

16

A8K0S8
ALGADAPGDADAPDP

CMPK2

46

Q5EBM0
LPAEFSSQLPPDGGA

HEATR5B

1496

Q9P2D3
PGSADSEAEGLPYPA

CACNA1G

41

O43497
DELAGPGGQPSAFPS

CACNA1G

1951

O43497
GDFALDDGISPPTLG

FRMPD4

656

Q14CM0
GSGGPLLFDDLPPAS

ILKAP

41

Q9H0C8
ESVGFLDPAPAANPG

MAPKBP1

836

O60336
TLPALPEDGGSGAFP

FGF2

141

P09038
RPAPGSPSEGLFADG

DGKE

6

P52429
GFSGAPAEPDLSPRA

GPRIN3

46

Q6ZVF9
FAFEPLDLGVPSGDP

CACNA1H

2266

O95180
LDLGVPSGDPFLDGS

CACNA1H

2271

O95180
DGGNPFAEPSELDNP

SCAMP3

6

O14828
PGAGADFAVDPDQPL

OSGIN1

406

Q9UJX0
FDPFELGQGSSPEPE

GAREM2

701

Q75VX8
PFAELLEPGSLGGSD

SYT3

141

Q9BQG1
FGPLEGPSSLDAPSI

RNF207

6

Q6ZRF8
GSEDASLYGEPSPGP

SPATA2L

236

Q8IUW3
SGSSPFLDLTPEPGA

PSD

741

A5PKW4
FSLDELAGPGAEGPS

RNF8

156

O76064
PAFFEDPLGTSPLGS

AATK

636

Q6ZMQ8
RSPDAPAGALASGEP

NKX1-2

116

Q9UD57
PDSGTAPADPDSGAF

GNAS

411

Q5JWF2
APADPDSGAFAADPD

GNAS

416

Q5JWF2
GAAPDAPADPDAGAA

GNAS

456

Q5JWF2
ALGGPLDPQFVGPSD

FGD1

51

P98174
SFASPAGLEPGLPSD

SIPA1L3

1556

O60292
ACSSSGLPGPEPLEF

SHROOM1

246

Q2M3G4
DPSDAPFPSLDSPGK

TANK

346

Q92844
EPLAGTSEFLGPDGA

SLC41A1

31

Q8IVJ1
PDAAAPADAPSGLEA

SKI

526

P12755
EASLAAGAFPPPEDA

SCARF1

556

Q14162
AEAPESFPAAASPGD

SCARF1

641

Q14162
LSDGDLLTFGPEGPP

TCF19

96

Q9Y242
PGDTLSSPEFDSGPF

PLEKHG5

766

O94827
LGAPVAAFSPEPGLE

SLC2A4RG

121

Q9NR83
PLPDPGLAGAAAAAA

TBX2

51

Q13207
TAPFLSQADDPDDGP

SPNS1

6

Q9H2V7
GPGEAAASPEAEQFP

SNX21

26

Q969T3
GPDASEGATGPFLEP

PPP1R3F

436

Q6ZSY5
QPGADSSFPPALAEG

TBX6

21

O95947
APDLAFQGDGAPPLD

ZNF469

1776

Q96JG9
GPSPPAEGSTGDFAL

TNFRSF1B

246

P20333
SPPPALEDTAAAGAA

GTF3C1

1911

Q12789
APDPGADPLASSVNG

TCTN2

541

Q96GX1
FPGAGESFPPPADAE

TBX21

86

Q9UL17
AAPEPGDSPGFLSGA

ZBTB7A

286

O95365
YAGLSGLDPDPSLPT

ZNF541

46

Q9H0D2
PSQPEAFEDPGAAGL

ZBTB3

391

Q9H5J0
PSPAPALDDFSGLGE

KMT2D

1106

O14686
LSGPILGPGSFPSDD

KMT2D

2756

O14686