Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF1220

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

3.28e-08111785PF06758
DomainNBPF_dom

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

3.28e-08111785IPR010630
DomainNBPF

NBPF3 NBPF11 NBPF1 NBPF9 NBPF14

3.28e-08111785PS51316
DomainDUF1220

NBPF3 NBPF11 NBPF1 NBPF9

9.68e-0791784SM01148
DomainEGF

RELN ZAN FAT3 VWDE ADAM22 HHIP EYS FAT1 CELSR1 BRINP2

8.84e-0523517810SM00181
DomainRibosomal_S27e

RPS27 RPS27L

9.03e-0521782IPR000592
DomainRibosomal_S27e_Zn-bd_dom

RPS27 RPS27L

9.03e-0521782IPR023407
DomainRibosomal_S27e

RPS27 RPS27L

9.03e-0521782PD004466
DomainRIBOSOMAL_S27E

RPS27 RPS27L

9.03e-0521782PS01168
DomainRibosomal_S27e

RPS27 RPS27L

9.03e-0521782PF01667
Domain-

RPS27 RPS27L

9.03e-05217822.20.25.100
DomainEGF_1

RELN ZAN FAT3 ITGB3 VWDE ADAM22 HHIP EYS FAT1 CELSR1

1.73e-0425517810PS00022
DomainEGF-like_CS

RELN ZAN FAT3 ITGB3 VWDE ADAM22 HHIP EYS FAT1 CELSR1

2.08e-0426117810IPR013032
DomainEGF_2

RELN ZAN FAT3 ITGB3 VWDE ADAM22 HHIP EYS FAT1 CELSR1

2.35e-0426517810PS01186
DomainAur

AURKC AURKB

2.69e-0431782IPR030616
DomainInsP3_rcpt-bd

ITPR1 ITPR2

2.69e-0431782IPR000493
Domain-

NBEAL1 FAT3 EYS FAT1 CELSR1 LRBA

2.97e-049517862.60.120.200
DomainDH_1

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

3.34e-04631785PS00741
DomainEGF_3

RELN ZAN FAT3 VWDE ADAM22 HHIP EYS FAT1 CELSR1

4.34e-042351789PS50026
DomainVWF_type-D

VWF ZAN VWDE

4.35e-04161783IPR001846
DomainVWFD

VWF ZAN VWDE

4.35e-04161783PS51233
DomainVWD

VWF ZAN VWDE

4.35e-04161783SM00216
DomainVWD

VWF ZAN VWDE

4.35e-04161783PF00094
DomainLAM_G_DOMAIN

FAT3 EYS FAT1 CELSR1

4.57e-04381784PS50025
DomainRhoGEF

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

4.77e-04681785SM00325
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMK1G AURKC CAMKV TSSK3 AURKB

5.10e-04691785IPR020636
DomainRhoGEF

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

5.45e-04701785PF00621
DomainDH_2

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

5.45e-04701785PS50010
DomainLaminin_G_2

FAT3 EYS FAT1 CELSR1

5.58e-04401784PF02210
Domain-

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

5.82e-047117851.20.900.10
DomainDH-domain

ARHGEF12 PLEKHG5 PLEKHG3 DNMBP SOS1

5.82e-04711785IPR000219
DomainEGF-like_dom

RELN ZAN FAT3 VWDE ADAM22 HHIP EYS FAT1 CELSR1

6.58e-042491789IPR000742
DomainFd_Rdtase_FAD-bd

POR DUOX1 NOS3

7.37e-04191783IPR017927
DomainFAD_FR

POR DUOX1 NOS3

7.37e-04191783PS51384
DomainRiboflavin_synthase-like_b-brl

POR DUOX1 NOS3

7.37e-04191783IPR017938
DomainLamG

FAT3 EYS FAT1 CELSR1

8.04e-04441784SM00282
DomainCA

FAT3 FREM2 FAT1 CELSR1 CDH10 CDH16

8.22e-041151786SM00112
DomainDUF4704

NBEAL1 LRBA

8.86e-0451782IPR031570
DomainDUF4704

NBEAL1 LRBA

8.86e-0451782PF15787
DomainCadherin

FAT3 FREM2 FAT1 CELSR1 CDH10 CDH16

9.40e-041181786IPR002126
DomainRIH_assoc-dom

ITPR1 ITPR2

1.32e-0361782IPR013662
DomainFAD_binding_1

POR NOS3

1.32e-0361782PF00667
DomainPH_BEACH

NBEAL1 LRBA

1.32e-0361782PF14844
Domain-

POR NOS3

1.32e-03617821.20.990.10
DomainIns145_P3_rec

ITPR1 ITPR2

1.32e-0361782PF08709
DomainRIH_assoc

ITPR1 ITPR2

1.32e-0361782PF08454
DomainRIH_dom

ITPR1 ITPR2

1.32e-0361782IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

1.32e-0361782IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

1.32e-0361782IPR015925
DomainFAD-binding_1

POR NOS3

1.32e-0361782IPR003097
Domain-

ITPR1 ITPR2

1.32e-03617821.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2

1.32e-0361782PF01365
DomainNADPH_Cyt_P450_Rdtase_dom3

POR NOS3

1.32e-0361782IPR023173
DomainARM-type_fold

DOCK2 NBEAL1 FRYL CWC22 FMNL2 ITPR1 ITPR2 ELMO2 LRBA NIPBL

1.57e-0333917810IPR016024
DomainKinase-like_dom

TLK2 ROR2 CAMK1G MAP3K4 AURKC MYO3A CAMKV SYK TSSK3 MAPK11 LYN AURKB SOS1

2.13e-0354217813IPR011009
DomainLaminin_G

FAT3 EYS FAT1 CELSR1

2.27e-03581784IPR001791
DomainFlavodoxin/NO_synth

POR NOS3

2.44e-0381782IPR008254
DomainFlavdoxin-like

POR NOS3

2.44e-0381782IPR001094
DomainPH-BEACH_dom

NBEAL1 LRBA

2.44e-0381782IPR023362
DomainFLAVODOXIN_LIKE

POR NOS3

2.44e-0381782PS50902
Domain-

NBEAL1 LRBA

2.44e-03817822.30.29.40
DomainPH_BEACH

NBEAL1 LRBA

2.44e-0381782PS51783
DomainFlavodoxin_1

POR NOS3

2.44e-0381782PF00258
DomainEGF_extracell

RELN ITGB3 ADAM22 HHIP

2.57e-03601784IPR013111
DomainEGF_2

RELN ITGB3 ADAM22 HHIP

2.57e-03601784PF07974
DomainProt_kinase_dom

TLK2 ROR2 CAMK1G MAP3K4 AURKC MYO3A CAMKV SYK TSSK3 MAPK11 LYN AURKB

2.60e-0348917812IPR000719
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 SYK LYN

6.72e-0791234M47852
PathwaySIG_BCR_SIGNALING_PATHWAY

CR2 ITPR1 ITPR2 SYK LYN SOS1

2.75e-06461236M8626
PathwayREACTOME_INTEGRIN_SIGNALING

VWF ITGB3 SYK SOS1

8.29e-05271234M760
PathwayREACTOME_INTEGRIN_SIGNALING

VWF ITGB3 SYK SOS1

9.61e-05281234MM14958
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF3 NBPF8 NBPF12 NBPF11 NBPF1 NBPF9 NBPF10 NBPF14

1.10e-1321186816079250
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12 NBPF1 NBPF9 NBPF14

1.02e-0910186522973535
Pubmed

BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.

ITPR1 ITPR2 SYK LYN

3.94e-095186411782428
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 NBPF12 NBPF11 NBPF1 FAT1 NBPF9 NBPF10 NBPF14 HYDIN

3.71e-07170186923314748
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

C12orf56 DHX40 POLE DOCK10 NCLN CWC22 ITGB3 XAB2 ITPR1 SMYD4 FREM2 ELMO2 MARF1 DBR1 DDX11L8 USP33

4.96e-076501861638777146
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

POLE GEMIN5 KTI12 FRYL FAM110A NCLN DYSF PLEKHG5 NBPF1 ITPR2 PPP1R26 FAT1 CELSR1 WIZ ZMIZ2 ARHGAP44 PCNX1 ZFYVE26 LRBA DNMBP

2.22e-0611051862035748872
Pubmed

Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3.

ITGB3 SYK LYN

2.97e-06618639169439
Pubmed

Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.

VWF SYK LYN

2.97e-066186316788103
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ROR2 DOCK10 RPS27 STIL TMBIM1 PARP1 WWC2 EYS PTPN12 PCNX1 REEP4 UNC80

3.10e-064201861228065597
Pubmed

Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.

VWF SYK LYN

5.19e-067186311389024
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

VWF IDO1 NBEAL1 BTLA FMNL2 ITPR1 PLA2R1 FREM2 FAT1 BCAP29 TAF1 DBR1 UNC80

9.69e-065521861310737800
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

DOCK2 RPS16 PPCDC RPS27 PARP14 ITPR1 NUP205 PARP1 LYN NIPBL

1.63e-053401861029478914
Pubmed

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.

VWF IFNG NOS3

2.41e-0511186318469803
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

DOCK2 DHX40 ACO2 EXOSC1 GEMIN5 RPS27 CWC22 ADD2 ITPR1 ITPR2 MRPL22 SYK CPSF2 LYN

2.75e-057011861430196744
Pubmed

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.

VWF ITGB3

2.84e-052186222134168
Pubmed

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway.

AURKC AURKB

2.84e-052186233725274
Pubmed

Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells.

SYK LYN

2.84e-052186221730355
Pubmed

9q22 Deletion--first familial case.

ROR2 SYK

2.84e-052186221693067
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

2.84e-052186223582047
Pubmed

Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme.

AURKC AURKB

2.84e-052186234465813
Pubmed

Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity.

VWF ITGB3

2.84e-052186218045606
Pubmed

Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis.

AURKC AURKB

2.84e-052186217192404
Pubmed

Indoleamine 2,3-dioxygenase mediates cell type-specific anti-measles virus activity of gamma interferon.

IDO1 IFNG

2.84e-052186215919929
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

2.84e-052186218708078
Pubmed

Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.

AURKC AURKB

2.84e-052186224586209
Pubmed

Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1.

IDO1 IFNG

2.84e-052186229515027
Pubmed

Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis.

AURKC AURKB

2.84e-052186233172986
Pubmed

The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage.

IDO1 IFNG

2.84e-052186233390854
Pubmed

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis.

VWF STXBP5

2.84e-052186221163921
Pubmed

Assessment of interferon gamma and indoleamine 2,3-dioxygenase 1 analysis during respiratory syncytial virus infection in infants in Italy: an observational case-control study.

IDO1 IFNG

2.84e-052186235228282
Pubmed

Lyn and Syk kinases are sequentially engaged in phagocytosis mediated by Fc gamma R.

SYK LYN

2.84e-052186212471110
Pubmed

IFN-gamma amplifies IL-6 and IL-8 responses by airway epithelial-like cells via indoleamine 2,3-dioxygenase.

IDO1 IFNG

2.84e-052186212471139
Pubmed

Neddylation modification of ribosomal protein RPS27L or RPS27 by MDM2 or NEDP1 regulates cancer cell survival.

RPS27 RPS27L

2.84e-052186232779270
Pubmed

Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B.

AURKC AURKB

2.84e-052186224603334
Pubmed

Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy.

AURKC AURKB

2.84e-052186228369513
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

2.84e-052186215201137
Pubmed

Endothelial von Willebrand factor release due to eNOS deficiency predisposes to thrombotic microangiopathy in mouse aging kidney.

VWF NOS3

2.84e-052186220363914
Pubmed

IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.

IDO1 IFNG

2.84e-052186226914138
Pubmed

Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.

DOCK2 CDH10

2.84e-052186224951259
Pubmed

Increased activity of indoleamine 2,3-dioxygenase in serum from acutely infected dengue patients linked to gamma interferon antiviral function.

IDO1 IFNG

2.84e-052186219264674
Pubmed

Induction of indoleamine 2,3-dioxygenase in vascular smooth muscle cells by interferon-gamma contributes to medial immunoprivilege.

IDO1 IFNG

2.84e-052186217911610
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

2.84e-052186219120126
Pubmed

Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.

NBPF11 NBPF1

2.84e-05218627700633
Pubmed

Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases.

SYK LYN

2.84e-05218627895172
Pubmed

Protein ISGylation and free ISG15 levels are increased by interferon gamma in breast cancer cells.

IFNG ISG15

2.84e-052186229626479
Pubmed

Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B cell activation includes a site that negatively regulates signaling.

SYK LYN

2.84e-05218629820500
Pubmed

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells.

AURKC AURKB

2.84e-052186215499654
Pubmed

Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation.

IDO1 IFNG

2.84e-052186218205804
Pubmed

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy.

IDO1 IFNG

2.84e-052186225899824
Pubmed

Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO.

IDO1 IFNG

2.84e-052186216785507
Pubmed

Free iron ions decrease indoleamine 2,3-dioxygenase expression and reduce IFNgamma-induced inhibition of Chlamydia trachomatis infection.

IDO1 IFNG

2.84e-052186219306922
Pubmed

Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development.

AURKC AURKB

2.84e-052186222778418
Pubmed

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.

PARP1 ZNF432

2.84e-052186237823600
Pubmed

IDO expression on decidual and peripheral blood dendritic cells and monocytes/macrophages after treatment with CTLA-4 or interferon-gamma increase in normal pregnancy but decrease in spontaneous abortion.

IDO1 IFNG

2.84e-052186216421220
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

WASHC4 POLE EXOSC1 RPS16 NCAPH MAP3K4 NUP205 MRPL22 EIF2S1 LRBA DHX29 NIPBL CDC23 AURKB

2.88e-057041861429955894
Pubmed

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

DOCK2 RELN LYN

4.14e-0513186322724066
Pubmed

Defining the membrane proteome of NK cells.

DOCK2 DOCK10 POR GEMIN5 RPS16 NCLN PARP14 NCAPH XAB2 ITPR1 NUP205 ITPR2 PARP1 BCAP29 EIF2S1 MARF1 LRBA CPSF2

6.07e-0511681861819946888
Pubmed

Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase.

ITGB3 LYN

8.50e-053186226291522
Pubmed

Nitric oxide inhibits von Willebrand factor-mediated platelet adhesion and spreading through regulation of integrin alpha(IIb)beta(3) and myosin light chain.

VWF ITGB3

8.50e-053186219765213
Pubmed

The N-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function.

SYK LYN

8.50e-053186216118313
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2

8.50e-053186217437169
Pubmed

PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells.

PARP14 PARP1

8.50e-053186219147789
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2

8.50e-053186218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2

8.50e-053186236350267
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2

8.50e-053186211413485
Pubmed

Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection.

IDO1 IFNG

8.50e-053186222474038
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

8.50e-053186226009177
Pubmed

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family.

AURKC AURKB

8.50e-053186229283376
Pubmed

Mice lacking the gene for inducible or endothelial nitric oxide are resistant to sporocyst induced Sarcocystis neurona infections.

IFNG NOS3

8.50e-053186211777610
Pubmed

Comparative study on the histomorphology and molecular biology of radial artery conduits in patients with diabetes mellitus who underwent coronary bypass surgery.

VWF NOS3

8.50e-053186222972845
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2

8.50e-05318621693919
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2

8.50e-053186231979185
Pubmed

CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease.

VWF STXBP5

8.50e-053186225832887
Pubmed

Gene expression of Aurora kinases in prostate cancer and nodular hyperplasia tissues.

AURKC AURKB

8.50e-053186223075505
Pubmed

Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells.

IDO1 IFNG

8.50e-053186225450809
Pubmed

Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites.

SYK LYN

8.50e-053186210942405
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2

8.50e-05318629808793
Pubmed

The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.

IDO1 IFNG

8.50e-053186226285873
Pubmed

Solid-phase von Willebrand factor contains a conformationally active RGD motif that mediates endothelial cell adhesion through the alpha v beta 3 receptor.

VWF ITGB3

8.50e-05318627505120
Pubmed

Modulation of epigenetic factors during the early stages of HIV-1 infection in CD4+ T cells in vitro.

AURKC AURKB

8.50e-053186230077875
Pubmed

Aurora kinase B inhibits aurora kinase A to control maternal mRNA translation in mouse oocytes.

AURKC AURKB

8.50e-053186234636397
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2

8.50e-053186218194433
Pubmed

Suppression of PKR promotes network excitability and enhanced cognition by interferon-γ-mediated disinhibition.

IFNG EIF2S1

8.50e-053186222153080
Pubmed

Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis.

IDO1 IFNG

8.50e-053186219168733
Pubmed

Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein.

XAB2 DBR1

8.50e-053186225671812
Pubmed

A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation.

PARP14 IFNG

8.50e-053186230848916
Pubmed

BLNK mediates Syk-dependent Btk activation.

SYK LYN

8.50e-053186211226282
Pubmed

Deregulation of Aurora kinase gene expression in human testicular germ cell tumours.

AURKC AURKB

8.50e-053186220629650
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2

8.50e-053186218241669
Pubmed

GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer.

IDO1 GBP2

8.50e-053186233552086
Pubmed

Alterations in expression of endometrial endothelial nitric oxide synthase and alpha(v)beta(3) integrin in women with endometriosis.

ITGB3 NOS3

8.50e-053186212372469
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2

8.50e-053186219068129
Pubmed

Detailed analysis of Japanese patients with adenosine deaminase 2 deficiency reveals characteristic elevation of type II interferon signature and STAT1 hyperactivation.

ADA2 IFNG

8.50e-053186233529688
Pubmed

SAR156497, an exquisitely selective inhibitor of aurora kinases.

AURKC AURKB

8.50e-053186225369539
Pubmed

Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein.

SYK LYN

8.50e-053186215795233
Pubmed

Overexpression of an Aurora-C kinase-deficient mutant disrupts the Aurora-B/INCENP complex and induces polyploidy.

AURKC AURKB

8.50e-053186215917996
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

8.50e-053186217327232
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

8.50e-053186223223241
Pubmed

Inhibition of human herpes simplex virus type 2 by interferon gamma and tumor necrosis factor alpha is mediated by indoleamine 2,3-dioxygenase.

IDO1 IFNG

8.50e-053186215374002
Pubmed

Specialize and Divide (Twice): Functions of Three Aurora Kinase Homologs in Mammalian Oocyte Meiotic Maturation.

AURKC AURKB

8.50e-053186228359584
Cytoband1q21.1

NBPF8 NBPF11 NBPF9 NBPF10 NBPF14

5.55e-066218651q21.1
Cytoband9q22

ROR2 SYK RORB

6.04e-051918639q22
Cytoband7q22

RELN ZAN TFR2

4.97e-043818637q22
GeneFamilyNeuroblastoma breakpoint family

NBPF3 NBPF8 NBPF12 NBPF26 NBPF11 NBPF1 NBPF9 NBPF10 NBPF14

1.29e-14231199662
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

1.28e-0431192297
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 PLEKHG3 DNMBP SOS1

9.39e-04661194722
GeneFamilyS ribosomal proteins

RPS16 RPS27 RPS27L

1.43e-03341193728
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 LRBA

1.50e-03911921230
CoexpressionGSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP

NAT8L STIL RUNX3 PARP14 ITGB3 PTPN12 ZMIZ2 ALAS1 S100PBP

1.32e-052001859M6044
CoexpressionGSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP

RALGPS2 PARP14 PLEKHG5 ABCA9 RBSN SPATS2L TLR1 CALCRL

3.05e-051711858M6746
CoexpressionGSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN

ITGB3 IFNG ZMIZ2 MSL3 PCNX1 RORB ALAS1 SOS1

8.59e-051981858M3273
CoexpressionGSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN

PLIN2 VPS13D TLR1 PCNX1 ZFYVE26 MTO1 DNMBP CDH10

8.59e-051981858M5782
CoexpressionGSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP

DHX40 TADA1 ZFYVE26 DBR1 CPSF2 DHX29 CCDC93 ATP6V0A2

8.90e-051991858M3328
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP

NAT8L RALGPS2 GBP2 CR2 ADAM22 ISG15 MARF1 CALCRL

8.90e-051991858M6420
CoexpressionGSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN

GBP2 FRYL ITGB3 ITPR1 ISG15 GLCE LYN CDC23

9.22e-052001858M8849
CoexpressionGSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP

MTHFD2 POLE BTLA STIL NCAPH TAF1 IFT80 AURKB

9.22e-052001858M5041
CoexpressionGSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP

DOCK10 TMBIM1 RBSN SLC35D3 LRBA CALCRL DNMBP NIPBL

9.22e-052001858M5085
CoexpressionGSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP

EXOSC1 DYSF ADAM22 ITPR1 PRDX3 MSL3 CCDC93 S100PBP

9.22e-052001858M6424
CoexpressionGSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN

WASHC4 IDO1 GBP2 TMBIM1 SPATS2L ISG15 PCNX1 ZFYVE26

9.22e-052001858M8967
CoexpressionGSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP

NAT8L POLE DOCK10 POR PPCDC STIL NCAPH ADCY2

9.22e-052001858M6640
CoexpressionGSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN

RALGPS2 PPCDC GBP2 BTLA TMED3 MARF1 MAPK11 AURKB

9.22e-052001858M7828
CoexpressionGSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP

FRYL RPS27 CR2 ITPR1 NUP205 NBPF10 LRBA NIPBL

9.22e-052001858M4442
CoexpressionGSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

MTHFD2 POLE STIL NCAPH RPS27L SCRN2 CELSR1 AURKB

9.22e-052001858M9135
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 IDO1 DOCK10 BTLA RUNX3 NCAPH ADA2 SYK ASCL4 LYN

6.51e-0918618610305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCellfacs-MAT-Fat-3m-Lymphocytic-B_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 TLR1 SYK LYN

7.22e-0918818610a7158b5c94e6b356877f016e52f2c24a3f5d24d2
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 RALGPS2 BTLA CR2 ADD2 ITPR1 CELSR1 NBPF10 MARF1

3.34e-081651869fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

ADAMTSL1 WASHC4 ADA2 PLEKHG5 NBPF1 RBSN NBPF10 MARF1 PCNX1

5.54e-08175186935ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCellfacs-GAT-Fat-3m-Lymphocytic-B_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 SYK OTOP1 MAPK11 LYN

6.42e-0817818695b6f7e8a930c239db1f31edfb61b2b9228d28663
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 TLR1 SYK MAPK11

8.93e-081851869eb338fcda0b237c2e0b9b4b0daf51febbfe1d79c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 TLR1 SYK MAPK11

8.93e-081851869c31bb53852caf36964b83b28bcaee07b679da779
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 SYK MAPK11 LYN

9.35e-081861869d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 DOCK10 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

9.35e-0818618695fe11a5f9ff30f322ca88b44d592f241aabf397b
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 DOCK10 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

9.78e-0818718697191ee997c9d99e33b03caa7431b74132279bbf4
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 TLR1 SYK LYN

9.78e-081871869b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 TLR1 SYK LYN

9.78e-0818718693ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK LYN

1.02e-071881869f72bc8965872da4d7d7990895beadbe36752314f
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 STIL NCAPH VWDE FREM2 CELSR1 PKHD1 SYK AURKB

1.34e-071941869c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NBPF12 WASHC4 NBPF11 NBPF1 NBPF10 MARF1 SYK PCNX1

1.71e-071441868984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 RALGPS2 NBPF11 CR2 CELSR1 NBPF10 MARF1 SYK

3.83e-0716018687ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 SLC27A6 PFKFB1 ITGB3 NUP205 UNC5C IQUB CDH16

5.30e-0716718685c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NBPF12 WASHC4 NBPF11 NBPF1 NBPF10 MARF1 SYK PCNX1

5.30e-071671868948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK ASCL4

7.89e-0717618680f056597bc9e53176ce8670924ac925c801964b5
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK ASCL4

7.89e-071761868d04be5acf0be46adc3d2055f6f21358c02792817
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

WASHC4 ADA2 PLEKHG5 NBPF1 RBSN NBPF10 MARF1 PCNX1

9.74e-0718118680d07a67e8ee3bca687b378afbc4044434e63556d
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

1.02e-0618218686946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 SYK LYN

1.06e-061831868544939a0bfef082d361d88ef70d6f0923b8d9af9
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA CR2 PYHIN1 PARP1 TLR1 SYK LYN

1.06e-06183186820f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ZAN FAT3 FREM2 FAT1 PKHD1 HYDIN UNC80

1.10e-0618418682cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ZAN FAT3 FREM2 FAT1 PKHD1 HYDIN UNC80

1.10e-0618418682b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.10e-061841868eb41dce59eb0384c1671fbc76eb15daab2c8c49a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 RUNX3 CR2 PYHIN1 SYK

1.10e-0618418688fa7aa2a954f66576ada56670b4e1bb122864761
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.10e-061841868991500a874c5dd0d9111399520071da67bc6ac3d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ZAN FAT3 FREM2 FAT1 PKHD1 HYDIN UNC80

1.10e-061841868ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 RUNX3 CR2 PYHIN1 SYK

1.10e-061841868b5fbfcf8516c2dc20dffc36803692505a63f1297
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

1.15e-0618518683d035bb453a5942411da4eb8b3a1ca0961a089b2
ToppCelldroplet-Limb_Muscle-nan-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

1.15e-061851868a01d25a5642337cfcdef5fcd189b3150a5fad911
ToppCelldroplet-Lung-nan-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.15e-061851868d4076294571557c223f5b68244e9c53e1d8f0343
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 SYK LYN

1.15e-061851868bf4dbb5f139566750e50a81eb062ed8b9e5786c3
ToppCelldroplet-Lung-nan-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.20e-061861868683f59985fbc5d3ba2412c788b4647dbbf42699a
ToppCellfacs-BAT-Fat-3m-Lymphocytic-B_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.24e-06187186863cc89ce24d3f8fb13479a501a20bfbd798d151a
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.30e-0618818689526d9e035eadbb0dcd4ad6e79a3a2b7f7845d74
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 TLR1 SYK MAPK11

1.30e-0618818681f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.30e-0618818687c542b226240adcb7797be0ded6523e5732f0078
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 TLR1 SYK MAPK11

1.30e-06188186885746f95319e494efdc1bbc24331698688d3a900
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 SLC27A6 FREM2 CELSR1 ARHGAP44 PKHD1 SYK CDH10

1.30e-0618818680d86044bc340e3efb90d0022dd299873639d831c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 SYK LYN

1.40e-061901868ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 RALGPS2 NBPF1 CELSR1 NBPF10 MARF1 SYK

1.63e-0613518677743a01dc9c4542e910e7c0fe046004692a680bf
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 DOCK10 STIL RUNX3 NCAPH PYHIN1 CEACAM21 AURKB

1.70e-0619518687e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

STXBP5 CPA3 ITGB3 RTN2 SLC35D3 DYNLT5 ATP6V0A2 SOS1

1.70e-0619518689b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 RALGPS2 BTLA CR2 ADD2 ITPR1 SYK LYN

1.84e-061971868da61afba697ec49ca86e062d35a825280da558ac
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 RALGPS2 DOCK10 RUNX3 CR2 ADD2 TLR1 LYN

1.84e-061971868ccabb976b5d4800e87e550640454a893fdb3b1b6
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 DOCK10 FAM110A PARP14 ITPR2 TLR1 ASCL4 LYN

1.84e-06197186810190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 FAM110A RUNX3 PARP14 ITPR2 TLR1 SYK LYN

1.98e-0619918685ceeed92f831d068ff4bb3994f420002338330e7
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 IDO1 DOCK10 BTLA RUNX3 TLR1 SYK ASCL4

2.06e-06200186841a206350eff2a196ccc1a36a9636a87c74f6962
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWF PFKFB1 PLEKHG5 SLC5A4 CALCRL NOS3 UNC80

3.29e-0615018674f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC4 BTLA CR2 NBPF1 ITPR1 NBPF10 MARF1

4.84e-0615918672881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZAN POLE FAT3 FREM2 PKHD1 HYDIN UNC80

5.47e-061621867bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IDO1 DOCK10 BTLA STIL ADA2 NBPF10 ASCL4

5.93e-06164186743045879505774ac0d9b7f760557955564f06d00
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 RALGPS2 DOCK10 PYHIN1 ZMIZ2 TLR1 SYK

6.17e-0616518678a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTLA FSIP2 MYO3A SLC35D3 TSSK3

7.16e-06641865bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTLA FSIP2 MYO3A SLC35D3 TSSK3

7.16e-06641865a3e852600c53b11175eb579e92962fa711f5678b
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTLA FSIP2 MYO3A SLC35D3 TSSK3

7.16e-06641865f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 RALGPS2 DOCK10 BTLA CR2 SYK LYN

7.80e-0617118678e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellImmune_cells-B_cell|Immune_cells / Lineage and Cell class

RALGPS2 CPA3 BTLA CR2 SYK MAPK11 LYN

8.10e-061721867b646894b691a99bf2742bd9da8e578dff0e87f1f
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

RELN IDO1 ROR2 CAMK1G FMNL2 ITIH1 ASCL4

8.10e-0617218671b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZAN MTHFD2 CPA3 FAM110A TFR2 CAMKV ATP6V0A2

8.42e-061731867a85cead231e03945fabbc7762540ad21fe4299df
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 FAT3 CPA3 RUNX3 ITGB3 PLEKHG3 DNMBP

8.42e-0617318672cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 FAT3 CPA3 RUNX3 ITGB3 PLEKHG3 DNMBP

8.42e-06173186711d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGPS2 RPS16 BTLA CR2 PYHIN1 PARP1 SYK

8.74e-0617418677c8704766dd4c80250754b5ee9907b342b9c2623
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGPS2 RPS16 BTLA CR2 PYHIN1 PARP1 SYK

8.74e-06174186726ca6ebaa0081108d44c01f8ca56a63724f1c99d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGPS2 RPS16 BTLA CR2 PYHIN1 PARP1 SYK

8.74e-0617418679aa2168d3bcef7cdc5a47442618cb8e9eb24c95b
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 PYHIN1 SYK LYN

9.07e-061751867738b3d476ac494e2e79b70b3b83bc1b7ae8396bd
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 RALGPS2 BTLA CR2 ITPR1 NBPF10 MARF1

9.41e-061761867ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 RALGPS2 BTLA CR2 ADD2 ITPR1 SYK

9.77e-061771867f54691e5558091c1734ab15153a10bff15ed171e
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

IDO1 BTLA DYSF FMNL2 RTN2 NBPF1 PLA2R1

1.01e-0517818670667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 PYHIN1 SYK LYN

1.01e-0517818675a4f97d19265577cfdb3e53f9dc3a9a02cfcffa9
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 TLR1 MAPK11

1.09e-051801867243622eee35d38748e945677ff115616e763e3b4
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 RALGPS2 DOCK10 BTLA CR2 SYK LYN

1.09e-0518018675650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 TLR1 MAPK11

1.09e-0518018673a8d9a71efe113d1df3933902a625c0a56812074
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ADAMTSL1 VWF ITGB3 CELSR1 CALCRL NOS3

1.13e-051811867cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCelldroplet-Thymus-nan-24m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS16 BTLA RPS27 CR2 ITIH1 SYK LYN

1.13e-0518118672a3092fbadd18967199f1203c11f0dd956417254
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.13e-051811867ce30724788d9b5c6dfa4f9f8d318c3d2565165ed
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 SYK MAPK11

1.13e-0518118673510e0ecd4f098e8553946c44c2a49587d543755
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

IDO1 BTLA RUNX3 ADD2 FSIP2 CALCRL MAPK11

1.13e-0518118675a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 PARP1 SYK

1.13e-05181186746de8c18e4ec8dc9d07f7c8cc7b5f48b9c613aae
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 RPS27 CR2 PYHIN1 PARP1 SYK

1.13e-0518118672c2b812cdd350271935d7007665c26093756ebee
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BTLA RPS27 CR2 PYHIN1 AURKC PARP1

1.13e-051811867ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCellControl-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

PP2D1 UNC5C NBPF10 MARF1 PKHD1 ASCL4

1.14e-051201866840d0ac995e2fa41996514753e4e03c4aa4a26d0
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

WASHC4 BTLA NBPF11 NBPF1 NBPF10 MARF1 PCNX1

1.17e-051821867877b6e611626628e709568747512f2827ebb2795
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF GBP2 FRYL PARP14 ISG15 CALCRL NOS3

1.17e-051821867840427d1c23d60482c943ff006b14007ed44d247
ToppCellfacs-Spleen|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 RPS16 BTLA RPS27 CR2 PYHIN1 TLR1

1.21e-051831867d8e87234d2fc2059536ed456993ab0557d118361
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 DOCK10 BTLA CR2 PYHIN1 SYK LYN

1.21e-051831867eb2f37c3d6d0502fb9eb512537fc2a002a1b92ed
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 DOCK10 BTLA CR2 PYHIN1 SYK LYN

1.21e-05183186756038766980a4186ecd3b4a327a91c12979d2364
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

IDO1 BTLA RUNX3 ADD2 FSIP2 CALCRL MAPK11

1.26e-051841867b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-051841867ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZKSCAN2 PP2D1 ADA2 IFNG MRPL22 PLEKHG3 PRDX3

1.26e-051841867af6522586d012e91241f3e06c60f9d1881e95646
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-0518418671d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-05184186776caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-0518418671fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-0518418672467207aaea307873ab286f89cfc7668a227a694
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 RALGPS2 DOCK10 BTLA CR2 SYK LYN

1.26e-051841867f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF GBP2 PARP14 DYSF ISG15 CALCRL NOS3

1.26e-051841867fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 RALGPS2 DOCK10 BTLA PYHIN1 SYK LYN

1.26e-0518418675cf7447faaec99fc37dfa8e92ff72cc2c7c05951
DrugPesticides

NBPF8 NBPF12 RPS16 NBPF11 CR2 ADCY2 NBPF1 NBPF9 UNC5C NBPF10 NBPF14

3.78e-0815018311ctd:D010575
Drugdinitroglycerol

POR RNF103 GSTCD NOS3

3.80e-06141834CID000079076
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

3.38e-0521722C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

3.38e-0521722C0003132
Diseaseeczema herpeticum (is_marker_for)

IDO1 IFNG

3.38e-0521722DOID:9123 (is_marker_for)
DiseaseBrain Hypoxia

ITPR1 ITPR2

3.38e-0521722C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

3.38e-0521722C0995195
Diseasecortical surface area measurement

RELN ADAMTSL1 ZAN SLC27A6 NBEAL1 FAT3 RALGPS2 DOCK10 ARHGEF12 CPA3 FRYL DYSF FMNL2 HHIP CELSR1 BCAP29 UNC5C PKHD1 CALCRL SOS1

1.19e-04134517220EFO_0010736
DiseaseOvarian Serous Adenocarcinoma

MAP3K4 MYO3A CAMKV

3.16e-04231723C1335177
Diseasenephritis (is_implicated_in)

PARP1 NOS3

3.34e-0451722DOID:10952 (is_implicated_in)
Diseasepreeclampsia, fetal genotype effect measurement

ITPR2 CDH10

3.34e-0451722EFO_0000668, EFO_0007959
Diseaseneuroimaging measurement

RELN SLC27A6 NBEAL1 FAT3 ROR2 RALGPS2 ARHGEF12 FRYL RPS27 DYSF PLIN2 HHIP CELSR1 PKHD1 CC2D2A CALCRL

5.47e-04106917216EFO_0004346
Diseasephosphate measurement

NBPF3 MTHFD2

6.96e-0471722EFO_0010968
Diseasehereditary lymphedema (is_implicated_in)

CELSR1 CALCRL

6.96e-0471722DOID:0050580 (is_implicated_in)
Diseasecortical thickness

RELN SLC27A6 NBEAL1 FAT3 RALGPS2 ARHGEF12 CPA3 DYSF FMNL2 HHIP DUOX1 VPS13D CELSR1 PKHD1 CALCRL CCDC171

8.40e-04111317216EFO_0004840
DiseaseHantavirus hemorrhagic fever with renal syndrome (is_marker_for)

ITGB3 IFNG

9.24e-0481722DOID:11266 (is_marker_for)
Diseaseretinal degeneration (implicated_via_orthology)

EYS FSCN2 NOS3

9.34e-04331723DOID:8466 (implicated_via_orthology)
Diseasepost operative nausea and vomiting

FAT3 SPATS2L

1.18e-0391722EFO_0004888
Diseasepulmonary tuberculosis (is_marker_for)

IDO1 ADA2 TLR1

1.21e-03361723DOID:2957 (is_marker_for)
Diseasetotal blood protein measurement

ARHGEF12 PPCDC RUNX3 DYSF PARP1 PKHD1 SYK HYDIN SOS1

1.34e-034491729EFO_0004536
DiseaseAutism Spectrum Disorders

RELN ITGB3 CDH10 UNC80

1.56e-03851724C1510586
Diseaseend stage renal disease (is_implicated_in)

VWF ITGB3 NOS3

1.76e-03411723DOID:783 (is_implicated_in)
Diseasephysical activity

ADAMTSL1 PKHD1 NIPBL NLRP8

1.78e-03881724EFO_0003940
DiseaseLiver Cirrhosis, Experimental

VWF DOCK10 GBP2 DYSF ITGB3 TMBIM1 ACOX2 PLIN2 IFNG FAT1 HSD17B6 NOS3

2.03e-0377417212C0023893
Diseaseendometrial carcinoma (is_implicated_in)

POLE RUNX3

2.15e-03121722DOID:2871 (is_implicated_in)
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

2.15e-03121722DOID:1441 (implicated_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ITGB3 ITPR1 PARP1 EIF2S1 NOS3

2.32e-031571725DOID:224 (biomarker_via_orthology)
DiseaseAdenocarcinoma of large intestine

POLE ROR2 CAMKV TAF1

2.44e-03961724C1319315
DiseaseCommon variable immunodeficiency

CR2 LRBA

2.53e-03131722cv:C0009447
Diseasexanthine measurement

ADAM22 EYS

2.53e-03131722EFO_0010548
DiseaseAlzheimer's Disease

RELN EIF2S1 UNC5C NOS3

2.93e-031011724C0002395
Diseasetriacylglycerol 46:0 measurement

CWC22 RORB

3.37e-03151722EFO_0010400
DiseaseAase Smith syndrome 2

RPS27 ADA2

3.37e-03151722C2931850
DiseaseGraves' disease (is_marker_for)

ITGB3 IFNG

3.37e-03151722DOID:12361 (is_marker_for)
DiseaseHepatitis

IFNG PARP1

3.37e-03151722C0019158
Diseasecentral nervous system disease (implicated_via_orthology)

ACO2 GEMIN5

3.84e-03161722DOID:331 (implicated_via_orthology)
DiseaseHuntington's disease (biomarker_via_orthology)

ITPR1 NOS3

3.84e-03161722DOID:12858 (biomarker_via_orthology)
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

CAMK1G DYSF MRPL22 UNC5C

3.98e-031101724EFO_0803335
DiseaseMalignant neoplasm of breast

MAGEA4 VWF IDO1 ACO2 DYSF IFNG PARP1 ZNF432 ZFYVE26 LRBA NIPBL NOS3 CDH10 NLRP8

4.26e-03107417214C0006142
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

PARP1 TLR1

4.34e-03171722DOID:8677 (biomarker_via_orthology)
Diseasefactor VIII measurement, coronary artery disease

VWF NBEAL1 STXBP5 NOS3

4.38e-031131724EFO_0001645, EFO_0004630
DiseaseAtherosclerosis

IFNG PARP1 NOS3

4.98e-03591723C0004153
DiseaseAtherogenesis

IFNG PARP1 NOS3

4.98e-03591723C1563937
Diseasevon Willebrand factor measurement, coronary artery disease

VWF NBEAL1 STXBP5 NOS3

5.11e-031181724EFO_0001645, EFO_0004629
Diseaseopen-angle glaucoma

ARHGEF12 FMNL2 ITGB3 ITIH1 PKHD1

5.34e-031911725EFO_0004190
Diseasebipolar disorder (is_marker_for)

RELN VWF

5.41e-03191722DOID:3312 (is_marker_for)
Diseasethrombin activatable fibrinolysis inhibitor activation peptide measurement

DOCK10 ITPR1

5.41e-03191722EFO_0008582
Diseaseglomerulonephritis (is_marker_for)

ITGB3 IFNG

5.41e-03191722DOID:2921 (is_marker_for)
Diseasefactor VIII measurement, Ischemic stroke

VWF STXBP5

5.41e-03191722EFO_0004630, HP_0002140
Diseasetoxic shock syndrome (is_marker_for)

IDO1 IFNG

5.41e-03191722DOID:14115 (is_marker_for)
Diseaseserum zinc measurement

ADAMTSL1 PPCDC

5.41e-03191722EFO_0005268

Protein segments in the cluster

PeptideGeneStartEntry
LQKALGVRQYHVASV

ACO2

11

Q99798
SIYLNVEAVNTHREK

PFKFB1

436

P16118
NTALRRKVESIIHSY

ACOX2

46

Q99424
VAYHNIRDIDKALSI

CDC23

271

Q9UJX2
NVYLARLKESHFIVA

AURKC

56

Q9UQB9
SETHIYQVRLKDSLV

CPSF2

601

Q9P2I0
VQLYIKRQSEHSILA

BTLA

36

Q7Z6A9
NLTVRQHLEVYAAVK

ABCA9

1376

Q8IUA7
NQLIAAYVIDTHVRT

CEACAM21

76

Q3KPI0
ITYVEKDSLVQRLAH

CCDC171

931

Q6TFL3
VNHILKDVVTSYLQV

DYNLT5

81

Q8N7M0
RLSVVHTNTYAKSVV

ADAM22

256

Q9P0K1
AVREVRKYSSVHTIE

BCAP29

66

Q9UHQ4
LYLQHIRESACVKVV

DNMBP

1046

Q6XZF7
IHYVSNAQLIAFKER

GLCE

321

O94923
KETHVLRVKAVDYST

CELSR1

316

Q9NYQ6
ERYKVIALHSILSTQ

DHX29

896

Q7Z478
YILTEQHSKRVAVIL

CBWD5

61

Q5RIA9
AHVRTLKVLDQVFYQ

ARHGEF12

801

Q9NZN5
HIQYLSTIIKDSRRV

NBEAL1

1021

Q6ZS30
INFKDLLSVVYISHR

NBEAL1

1216

Q6ZS30
IVENHTAYLVKILTS

RAD51AP2

621

Q09MP3
VFDLTKHQTYAVVER

RAB25

91

P57735
LRSHFQKYQVSEISI

RBM44

846

Q6ZP01
AARIDHYVVEVNKLI

RBSN

111

Q9H1K0
AEIIRKYVKNTHATT

PARP1

811

P09874
HVEYLRFLQTIVKAD

ITPR2

1306

Q14571
VAVQHFSLLYKTVQR

NCLN

541

Q969V3
LTEKQYIATIHSRLQ

NUP205

301

Q92621
HIYITQLAEKFDLRT

DUOX1

1451

Q9NRD9
AILNREVKDHYTLIV

FAT1

106

Q14517
VKALVSLRSYHLQIV

IDO1

336

P14902
VLAKISSEHARTYIQ

MAPK11

246

Q15759
HTFIRKVYSIISVQL

TMBIM1

96

Q969X1
ETSYVKVLEHVVRVN

MAGEA4

281

P43358
LAETSYVKVLEHVVR

MAGEA8

281

P43361
EKEHNRTVTIYLTIK

EYS

2166

Q5T1H1
LNVAFSREQSHKVYV

POR

591

P16435
SRHDVVILDSLNYIK

KTI12

71

Q96EK9
KVTSRFAHYVVTSQV

ITIH1

61

P19827
FYAKHTAQIEIVRLD

ITPR1

2196

Q14643
RALSTAAVHYQQIKE

ALAS1

46

P13196
FVSQALNDYHKVVLR

NLRP8

621

Q86W28
RLKIEATYESVLFHQ

MTO1

606

Q9Y2Z2
AARNVLLVTQHYAKI

SYK

496

P43405
KTVYSILRHVAEVLE

EIF2S1

106

P05198
TKDVTLCHQLTYIVA

LRRC53

16

A6NM62
YEVRLTQTVAHLKQQ

ISG15

96

P05161
IHTIYTVRSKDNANR

FREM2

3011

Q5SZK8
FTHVYAALVAIINSK

CWC22

211

Q9HCG8
YILTEQHSKRVAVIL

CBWD2

61

Q8IUF1
YILTEQHSKRVAVIL

CBWD1

61

Q9BRT8
IVTDNIVRTVFHKLY

FSIP2

1841

Q5CZC0
IHLSQARLKTYADVI

FSIP2

2341

Q5CZC0
ARHVTTSVVTYLKNF

FSIP2

3446

Q5CZC0
YKSLIQIHRVIQSDT

FSIP2

5036

Q5CZC0
YSKHLVAQLAQEIFR

ADAMTSL1

1096

Q8N6G6
LSVRNVKALAEYFHI

EFCAB9

21

A8MZ26
TVLYEAIVSHEKNLV

PCNX1

1876

Q96RV3
SHSRKAEVIYRVQIV

PCNX1

2236

Q96RV3
SQTYLEVIKAEHVVV

MORC3

131

Q14149
AKYVKSLHVANTRQE

FAM110A

51

Q9BQ89
RVLTVKQVAHLDYNF

FRYL

1676

O94915
IITILESYVKHFAIN

MSL3

206

Q8N5Y2
DVIERVIQYTKFHLQ

NIPBL

1331

Q6KC79
EKAYRKVLSHVIEQT

DNAJC28

96

Q9NX36
AAKYRDHVTATQLIQ

LRBA

1941

P50851
QLHYVTELTDRIKAN

GBP2

141

P32456
SSINSRFAKVHILYV

EXOSC1

76

Q9Y3B2
NYIRLSFHTVEDLVK

POLE

151

Q07864
YKVLVHSQERELTQL

NBPF1

366

Q3BBV0
DHVEVVLVSTRKQNY

RELN

3421

P78509
SLVIQQVLSAVKYLH

CAMK1G

121

Q96NX5
EINVAVLHSYQLAKV

NOS3

401

P29474
TVDVKINHRHYTVNL

PARP14

1566

Q460N5
YKVLVHSQERELTQL

NBPF3

151

Q9H094
VLAATIAVVVVYLIH

OTOP1

321

Q7RTM1
TNSVKLYRHSVLEVL

BTBD19

91

C9JJ37
LYVKRHTNVSILYAD

ADCY2

281

Q08462
FIELYRQISAVHKET

CCDC93

501

Q567U6
ERLIVQSYVLEHQKT

HYDIN

1556

Q4G0P3
RVIKASLNYAHLVVS

IFT80

336

Q9P2H3
HVDTVLAYRQKFLET

IFT80

711

Q9P2H3
RQVVSHLQDKYVFIT

HSD17B6

21

O14756
HATVYRASLQFDLVK

C1QTNF5

156

Q9BXJ0
VTNFIRSHLNEIKVY

CPA3

286

P15088
IDTHRAIVAKYLQQV

CC2D2A

961

Q9P2K1
VRQVLEAVAYLHSLK

CAMKV

126

Q8NCB2
IVITLYVISKHRARN

CR2

991

P20023
IHRSYLKVAEVVNSE

DOCK10

1856

Q96BY6
QTHRQLKETLYETII

DOCK2

1271

Q92608
KITEYLERVQALHSA

CAPN7

56

Q9Y6W3
KLEAVEYAHISRLQA

GCNT4

191

Q9P109
AKVHQDTYIRIVLEN

ELMO2

381

Q96JJ3
RRLYTLKVEAENTHV

CDH10

341

Q9Y6N8
KSAHQVEQVLLAYSR

DDX11L8

741

A8MPP1
VSSTAKLYVHIERIN

FAT3

246

Q8TDW7
VINDYHFRIVKSLLS

PYHIN1

16

Q6K0P9
YILTEQHSKRVAVIL

CBWD3

61

Q5JTY5
YILTEQHSKRVAVIL

CBWD6

61

Q4V339
TKTEITYLRHVCIVN

ADGRF2

476

Q8IZF7
IKIIYSDHRSKDVAV

ADA2

286

Q9NZK5
VVREIYKDANTQVHT

FMNL2

436

Q96PY5
YLIEKNAHESVRVIV

MDH1B

241

Q5I0G3
ASKQVIVREFSQAYH

MARF1

1191

Q9Y4F3
TLQHDKLVRLYAVVT

LYN

296

P07948
AAEYHAQRLKAVIVI

IQUB

331

Q8NA54
VETLRAAIDYIKHLQ

ASCL4

111

Q6XD76
YKHVLTLTDQVTRFN

ITGB3

216

P05106
TIRSIYHVRNIEVYK

DBR1

146

Q9UK59
YSVTDLNVQRKAIHE

IFNG

121

P01579
HEVLVTTKVYARIVC

DHX40

671

Q8IX18
ITAHAASRIKTIYNA

RNF103

206

O00237
QKQLYLRSVIAHIED

S100PBP

321

Q96BU1
YAIVSFLHQSQKTVV

DYSF

1176

O75923
AVVLRHIIQKSYEAD

GSTCD

106

Q8NEC7
YLHTLIVVAVFAEKQ

CALCRL

236

Q16602
HALERTYQLLVQVKD

CDH16

201

O75309
LSRHEKEIDAYIVQA

REEP4

96

Q9H6H4
AQTLKIRAEVLSHYI

RALGPS2

111

Q86X27
DIRVHQAVLYVVSIL

OR10Q1

196

Q8NGQ4
KEYIQQLRSRTIVHT

MRPL22

191

Q9NWU5
VVLVAANHRYVSVRQ

FSCN2

261

O14926
QEHVIRLYSKQITIA

MAP3K4

1436

Q9Y6R4
TQVATYHRAIKVTVD

RUNX3

161

Q13761
TISLRVYRKVLQAVH

RTN2

391

O75298
LVHAAYLVLIQKASA

SLC35D3

166

Q5M8T2
IYQKAIEVLSDEHAR

XAB2

651

Q9HCS7
QKSATHLQRSLYVVE

SMYD4

716

Q8IYR2
THVNVKEKIYAVRSV

SPATS2L

6

Q9NUQ6
VYAVENHLKDILTSV

TADA1

176

Q96BN2
YKVLVHSQERELTQL

NBPF8

331

Q3BBV2
YKVLVHAQERELTQL

NBPF9

366

P0DPF3
YKVLVHAQERELTQL

NBPF10

366

Q6P3W6
YKVLVHSQERELTQL

NBPF11

366

Q86T75
YKVLVHSQERELTQL

NBPF12

366

Q5TAG4
YKVLVHAQERELTQL

NBPF14

26

Q5TI25
YKVLVHAQERELTQL

NBPF26

26

B4DH59
SHSYVLNKTRAAAVV

MTHFD2

81

P13995
SHVSERVKNKVYQLA

PLEKHG3

916

A1L390
YKITTVFSHAQTVVL

RPS27L

41

Q71UM5
REHLELIVKNSATYN

TAF1

1446

P21675
YIEVEQVSKTHAVIL

SCRN2

61

Q96FV2
AVQTKEQYELVHRAI

PTPN12

276

Q05209
GHVAQIYAIRQSISK

RPS16

76

P62249
TKSDSNYIIAIREHV

SETMAR

186

Q53H47
DHIRNAADISVIVIY

SLC5A4

21

Q9NY91
ETLRLVKAFQYVETH

PRDX3

211

P30048
LSVSRRNVYVHKDQS

PPP1R26

951

Q5T8A7
YNVRHFISAEEVKAI

WIZ

731

O95785
DVVTTYLREKHQIRV

PKHD1

481

P08F94
VVHKDLATRNVLVYD

ROR2

611

Q01974
KIDHQVSVYIVAVLE

SOS1

121

Q07889
VSAHVIIYRFSKQEV

STXBP5

521

Q5T5C0
QTLIEVQAEYHRKSL

ARHGAP44

216

Q17R89
DHILRVVEYTVSRKN

HHIP

316

Q96QV1
QVAHDNTVVASRKYI

PLA2R1

131

Q13018
KAYALVQVTVHRDTL

SLFNL1

91

Q499Z3
ISHNRIQYLDISVFK

TLR1

76

Q15399
DLTEQRYVAVKIHQL

TLK2

481

Q86UE8
YLLQKQDSRIEVHSI

BRINP2

516

Q9C0B6
YVTLRVSKEQDHFLI

ADD2

156

P35612
STKIYAVRVDAVHAD

NCAPH

161

Q15003
VVSNSENHILKYVVL

C12orf56

41

Q8IXR9
LEVAVVTTERAKHFY

PPCDC

46

Q96CD2
ASHNETYRRIVKVDL

AURKB

276

Q96GD4
VSAAHEARVEKFIYV

TGDS

126

O95455
HTEASYIRKLRVIIN

PLEKHG5

346

O94827
YINSDTLVREINKHT

VWDE

671

Q8N2E2
VVTEKTIRLAYRHAK

STIL

56

Q15468
SRQYASALKHIAEII

TTC30B

201

Q8N4P2
VAQDALRTQKELYHV

WWC2

106

Q6AWC2
VLKAVYLVLNHDISS

UNC80

656

Q8N2C7
LLRQYAATVINTAVH

UNC80

2206

Q8N2C7
RHLSISVVLKQTYQE

VWF

976

P04275
VATALENRSHKVRYS

SPO16

26

Q5VVC0
IVRTLDHKNIIQVYE

TSSK3

61

Q96PN8
LKTVIDSQTHYRLRE

TMED3

151

Q9Y3Q3
NAVIYVHNLKTVIES

GEMIN5

606

Q8TEQ6
QITHAIQYVVEFAKR

RORB

276

Q92753
QALEHLIYIVSTKSA

TRGV10

61

A0A0A0MS01
NHVFQLRDSVYKTLI

ZMIZ2

446

Q8NF64
SRQYASALKHIAEII

TTC30A

201

Q86WT1
LIVHQRNHTVEKSYL

ZNF432

416

O94892
VVHQLAALYISNKIA

WASHC4

161

Q2M389
LRSNYVKEKSVHAIQ

ZKSCAN2

301

Q63HK3
TVHLIEFARKNVYSA

PLIN2

256

Q99541
TYQDVDKRSSRVAHV

SLC27A6

81

Q9Y2P4
FYITIDHNLIIKQAR

UNC5C

216

O95185
YLIAVKQEHSRATAL

ZFYVE26

2486

Q68DK2
VLHLKAVVYVSLDNA

TFR2

496

Q9UP52
YKITTVFSHAQTVVL

RPS27

41

P42677
HITKKSYTEVIRDVI

SNRNP48

231

Q6IEG0
KVQIHSRASEYITDV

USP33

401

Q8TEY7
LNTRIQDLYTVLHKT

ATP6V0A2

266

Q9Y487
VSYIKAVHVTVFDLS

ZAN

1596

Q9Y493
IHVLFQYKSVSEVRV

PP2D1

511

A8MPX8
SSSIVLVLYRHKQQV

VN1R2

281

Q8NFZ6
TNLEHQIYARAEVKT

VPS13D

2866

Q5THJ4
EFSKHQLVARIQATY

MYO1H

701

Q8N1T3
ISEYLLEKSRVIHQA

MYO3A

506

Q8NEV4
KVLEFAVVHNYSAVV

NAT8L

231

Q8N9F0