Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OPN3 OR13C5 OR4D10 OR4D9 LAG3 OR4D1 GRIA3 OR4D11 RET PKD1L3 PTGER1 PTGFR OR14A16 OPRL1 GLP2R OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 HMCN2 OR13C9 OR13A1 OR13C2 OR10AC1 ROBO1 OR10G9 OR52K2 IL2RB GPRC5B FCMR	3.46e-10	1353	143	33	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.96e-09	431	143	18	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 GLP2R OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2 GPRC5B	3.72e-09	884	143	25	GO:0004930
GeneOntologyMolecularFunction	transporter activity	SLC36A4 SLC6A16 CFTR SIDT1 ABCC5 GRIA3 SLC10A3 KCNK16 AQP8 PKD1L3 AQP1 SLC1A2 ATP10A ANKH SLC1A5 SLC1A6 SLC22A1 NPC1L1 ABCB8 SLC10A6 ABCB11 TRPV6 SLC35E4 ATP1A1 TMED10 RFT1 SLC52A2 TAP1	1.13e-07	1289	143	28	GO:0005215
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC36A4 CFTR ABCC5 GRIA3 SLC10A3 SLC1A2 ANKH SLC1A5 SLC1A6 SLC22A1 SLC10A6 ABCB11 SLC52A2	1.95e-07	293	143	13	GO:0008514
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC36A4 SLC6A16 CFTR ABCC5 SLC10A3 SLC1A2 ANKH SLC1A5 SLC1A6 SLC22A1 ABCB8 SLC10A6 ABCB11 SLC35E4 ATP1A1 TAP1	3.31e-07	477	143	16	GO:0022804
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC36A4 SLC6A16 CFTR SIDT1 ABCC5 GRIA3 SLC10A3 KCNK16 AQP8 PKD1L3 AQP1 SLC1A2 ANKH SLC1A5 SLC1A6 SLC22A1 ABCB8 SLC10A6 ABCB11 TRPV6 SLC35E4 ATP1A1 TMED10 SLC52A2 TAP1	9.60e-07	1180	143	25	GO:0022857
GeneOntologyMolecularFunction	symporter activity	SLC36A4 SLC6A16 SLC10A3 SLC1A2 SLC1A5 SLC1A6 SLC22A1 SLC10A6	1.27e-05	150	143	8	GO:0015293
GeneOntologyMolecularFunction	ABC-type transporter activity	CFTR ABCC5 ABCB8 ABCB11 TAP1	2.60e-05	49	143	5	GO:0140359
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC36A4 SLC6A16 SLC10A3 SLC1A2 ANKH SLC1A5 SLC1A6 SLC22A1 SLC10A6 SLC35E4	5.55e-05	296	143	10	GO:0015291
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC10A3 SLC1A2 SLC1A6 SLC10A6	1.11e-04	35	143	4	GO:0005343
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC36A4 GRIA3 SLC10A3 SLC1A2 SLC1A5 SLC1A6 SLC10A6 ABCB11	1.25e-04	207	143	8	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC36A4 GRIA3 SLC10A3 SLC1A2 SLC1A5 SLC1A6 SLC10A6 ABCB11	1.29e-04	208	143	8	GO:0005342
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	CFTR ABCC5 ABCB8 ABCB11 ATP1A1 TAP1	1.34e-04	109	143	6	GO:0042626
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC10A3 AQP1 SLC22A1 SLC10A6 ABCB11	1.46e-04	70	143	5	GO:1901618
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC36A4 SLC1A2 SLC1A5 SLC1A6	2.08e-04	41	143	4	GO:0015175
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC10A3 SLC1A2 SLC1A6 SLC22A1 SLC10A6	2.91e-04	81	143	5	GO:0015370
GeneOntologyMolecularFunction	ABC-type peptide transporter activity	ABCB8 TAP1	3.03e-04	4	143	2	GO:0015440
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC36A4 AQP8 SLC1A2 SLC1A5 SLC22A1	3.26e-04	83	143	5	GO:0015101
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CFTR ABCC5 GRIA3 SLC10A3 KCNK16 AQP8 PKD1L3 AQP1 SLC1A2 ANKH SLC1A6 SLC22A1 SLC10A6 TRPV6 ATP1A1	3.59e-04	758	143	15	GO:0015318
GeneOntologyMolecularFunction	acidic amino acid transmembrane transporter activity	SLC1A2 SLC1A5 SLC1A6	3.75e-04	20	143	3	GO:0015172
GeneOntologyMolecularFunction	ATP-dependent activity	DDX47 DNHD1 CFTR ABCC5 ATP10A DNAH14 ABCB8 ABCB11 CHD6 ATP1A1 RFT1 DHX29 TAP1	4.80e-04	614	143	13	GO:0140657
GeneOntologyMolecularFunction	high-affinity L-glutamate transmembrane transporter activity	SLC1A2 SLC1A6	5.02e-04	5	143	2	GO:0005314
GeneOntologyMolecularFunction	glutamate:sodium symporter activity	SLC1A2 SLC1A6	5.02e-04	5	143	2	GO:0015501
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	GRIA3 SLC10A3 KCNK16 PKD1L3 AQP1 SLC1A2 SLC1A6 SLC22A1 SLC10A6 TRPV6 ATP1A1	5.32e-04	465	143	11	GO:0046873
GeneOntologyMolecularFunction	lipid transporter activity	SLC10A3 ATP10A SLC22A1 NPC1L1 SLC10A6 ABCB11 RFT1	5.36e-04	196	143	7	GO:0005319
GeneOntologyMolecularFunction	bile acid:sodium symporter activity	SLC10A3 SLC10A6	7.50e-04	6	143	2	GO:0008508
GeneOntologyMolecularFunction	double-stranded RNA adenosine deaminase activity	ADAR ADAD2	7.50e-04	6	143	2	GO:0003726
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SIDT1 ABCC5 ANKH SLC22A1	8.46e-04	59	143	4	GO:0015932
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC36A4 GRIA3 SLC1A2 SLC1A5 SLC1A6	9.55e-04	105	143	5	GO:0015171
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX47 CFTR ABCC5 ATP10A ABCB8 ABCB11 CHD6 ATP1A1 DHX29 TAP1	1.31e-03	441	143	10	GO:0016887
GeneOntologyMolecularFunction	tRNA-specific adenosine deaminase activity	ADAR ADAD2	1.39e-03	8	143	2	GO:0008251
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC10A3 SLC1A2 SLC1A6 SLC22A1 SLC10A6 ATP1A1	1.47e-03	171	143	6	GO:0015081
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC10A3 SLC1A2 SLC1A6 SLC22A1 SLC10A6	1.67e-03	119	143	5	GO:0015294
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC36A4 SLC1A2 SLC1A5 SLC1A6	1.69e-03	71	143	4	GO:0015179
GeneOntologyMolecularFunction	peptide transmembrane transporter activity	ABCB8 TAP1	1.77e-03	9	143	2	GO:1904680
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	CFTR ABCC5 ABCB8 ABCB11 ATP1A1 TAP1	1.80e-03	178	143	6	GO:0015399
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	SLC10A3 SLC10A6 ABCB11	1.83e-03	34	143	3	GO:0015125
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC5 SLC22A1 ABCB11	1.83e-03	34	143	3	GO:0042910
GeneOntologyMolecularFunction	macromolecule transmembrane transporter activity	SIDT1 ABCC5 TMED10	1.83e-03	34	143	3	GO:0022884
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	GRIA3 SLC10A3 KCNK16 AQP8 PKD1L3 AQP1 SLC1A2 SLC1A6 SLC22A1 SLC10A6 TRPV6 ATP1A1	1.87e-03	627	143	12	GO:0022890
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	SLC10A3 SLC22A1 SLC10A6 ABCB11	1.87e-03	73	143	4	GO:0170055
GeneOntologyMolecularFunction	L-aspartate transmembrane transporter activity	SLC1A5 SLC1A6	2.21e-03	10	143	2	GO:0015183
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	CFTR ABCC5	2.21e-03	10	143	2	GO:0043225
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH14 HTT	2.34e-03	37	143	3	GO:0045505
GeneOntologyMolecularFunction	prostaglandin receptor activity	PTGER1 PTGFR	2.68e-03	11	143	2	GO:0004955
GeneOntologyMolecularFunction	ammonium channel activity	AQP8 AQP1	3.21e-03	12	143	2	GO:0008519
GeneOntologyMolecularFunction	prostanoid receptor activity	PTGER1 PTGFR	3.21e-03	12	143	2	GO:0004954
GeneOntologyMolecularFunction	adenosine deaminase activity	ADAR ADAD2	3.77e-03	13	143	2	GO:0004000
GeneOntologyMolecularFunction	axon guidance receptor activity	HMCN2 ROBO1	3.77e-03	13	143	2	GO:0008046
GeneOntologyMolecularFunction	C4-dicarboxylate transmembrane transporter activity	SLC1A5 SLC1A6	5.03e-03	15	143	2	GO:0015556
GeneOntologyMolecularFunction	monocarboxylate:sodium symporter activity	SLC10A3 SLC10A6	5.03e-03	15	143	2	GO:0140161
GeneOntologyMolecularFunction	L-glutamate transmembrane transporter activity	SLC1A2 SLC1A6	5.03e-03	15	143	2	GO:0005313
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC5 ABCB11	5.03e-03	15	143	2	GO:0008559
GeneOntologyBiologicalProcess	sensory perception of smell	OR13C5 OR4D10 OR4D9 OR4D1 BBS1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	5.68e-10	465	143	19	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PKD1L3 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.14e-09	485	143	19	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.23e-09	432	143	18	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR13C5 OR4D10 OR4D9 OR4D1 BBS1 OR4D11 PKD1L3 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.33e-09	547	143	20	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PKD1L3 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	4.07e-09	524	143	19	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PKD1L3 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	2.21e-08	582	143	19	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PKD1L3 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.35e-07	722	143	20	GO:0051606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 GLP2R OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 ROBO1 OR10G9 OR52K2 GPRC5B HTT	1.02e-06	1395	143	27	GO:0007186
GeneOntologyBiologicalProcess	transepithelial water transport	CFTR AQP8 AQP1	1.30e-06	4	143	3	GO:0035377
GeneOntologyBiologicalProcess	sensory perception	OR13C5 OR4D10 OR4D9 OR4D1 BBS1 OR4D11 OTOR PKD1L3 AQP1 OR14A16 OPRL1 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.30e-06	1072	143	23	GO:0007600
GeneOntologyBiologicalProcess	regulation of anion channel activity	TCAF2 TCAF1 CFTR	6.43e-06	6	143	3	GO:0010359
GeneOntologyBiologicalProcess	L-aspartate import across plasma membrane	SLC1A2 SLC1A5 SLC1A6	6.43e-06	6	143	3	GO:0140009
GeneOntologyBiologicalProcess	regulation of monoatomic anion transmembrane transport	TCAF2 TCAF1 CFTR	1.78e-05	8	143	3	GO:1903959
GeneOntologyBiologicalProcess	L-aspartate transmembrane transport	SLC1A2 SLC1A5 SLC1A6	5.17e-05	11	143	3	GO:0070778
GeneOntologyBiologicalProcess	organic anion transport	SLC36A4 CFTR ABCC5 SLC10A3 AQP8 SLC1A2 ANKH SLC1A5 SLC1A6 SLC22A1 SLC10A6 ABCB11 SLC52A2	6.29e-05	515	143	13	GO:0015711
GeneOntologyBiologicalProcess	epithelial fluid transport	CFTR AQP8 AQP1	6.86e-05	12	143	3	GO:0042045
GeneOntologyBiologicalProcess	steroid biosynthetic process	CFTR AQP8 SDR42E2 DHCR7 NPC1L1 ABCB11 ATP1A1 HSD17B1	1.07e-04	209	143	8	GO:0006694
GeneOntologyBiologicalProcess	transepithelial transport	CFTR AQP8 AQP1 SLC1A2	1.36e-04	38	143	4	GO:0070633
GeneOntologyBiologicalProcess	positive regulation of anion channel activity	TCAF1 CFTR	1.43e-04	3	143	2	GO:1901529
GeneOntologyBiologicalProcess	positive regulation of anion transmembrane transport	TCAF1 CFTR	1.43e-04	3	143	2	GO:1903961
GeneOntologyBiologicalProcess	regulation of monoatomic anion transport	TCAF2 TCAF1 CFTR	2.47e-04	18	143	3	GO:0044070
GeneOntologyBiologicalProcess	positive regulation of monoatomic anion transport	TCAF1 CFTR	2.84e-04	4	143	2	GO:1903793
GeneOntologyBiologicalProcess	metanephric proximal tubule development	AQP1 SLC22A1	2.84e-04	4	143	2	GO:0072237
GeneOntologyBiologicalProcess	bile acid and bile salt transport	SLC10A3 AQP8 SLC10A6 ABCB11	3.13e-04	47	143	4	GO:0015721
GeneOntologyBiologicalProcess	aspartate transmembrane transport	SLC1A2 SLC1A5 SLC1A6	4.56e-04	22	143	3	GO:0015810
GeneOntologyBiologicalProcess	negative regulation of ceramide biosynthetic process	ORMDL1 ORMDL3	4.71e-04	5	143	2	GO:1900060
GeneOntologyBiologicalProcess	monoatomic ion transport	TCAF2 TCAF1 SLC6A16 CFTR ABCC5 GRIA3 KCNK16 PKD1L3 AQP1 SLC1A2 ATP10A SLC1A6 SLC22A1 ABCB8 SLC10A6 TRPV6 SARAF ATP1A1 NKAIN3 HTT CYBA	5.18e-04	1374	143	21	GO:0006811
GeneOntologyBiologicalProcess	lipid biosynthetic process	CFTR AQP8 SACM1L ORMDL1 ORMDL3 CHPT1 SCD SDR42E2 DHCR7 NPC1L1 ABCB11 ATP1A1 HSD17B1 MPPE1 PIGO	5.33e-04	813	143	15	GO:0008610
GeneOntologyBiologicalProcess	carboxylic acid transport	SLC36A4 ABCC5 SLC10A3 AQP8 SLC1A2 SLC1A5 SLC1A6 SLC22A1 SLC10A6 ABCB11	5.90e-04	410	143	10	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	SLC36A4 ABCC5 SLC10A3 AQP8 SLC1A2 SLC1A5 SLC1A6 SLC22A1 SLC10A6 ABCB11	6.13e-04	412	143	10	GO:0015849
GeneOntologyBiologicalProcess	vitamin transport	ABCC5 SLC22A1 NPC1L1 SLC52A2	6.15e-04	56	143	4	GO:0051180
GeneOntologyBiologicalProcess	amino acid import across plasma membrane	SLC36A4 SLC1A2 SLC1A5 SLC1A6	7.03e-04	58	143	4	GO:0089718
GeneOntologyBiologicalProcess	positive regulation of enamel mineralization	CFTR AMTN	7.03e-04	6	143	2	GO:0070175
GeneOntologyBiologicalProcess	intracellular sphingolipid homeostasis	ORMDL1 ORMDL3	7.03e-04	6	143	2	GO:0090156
GeneOntologyBiologicalProcess	canalicular bile acid transport	AQP8 ABCB11	7.03e-04	6	143	2	GO:0015722
GeneOntologyBiologicalProcess	organic hydroxy compound biosynthetic process	OPN3 CFTR AQP8 DHCR7 NPC1L1 ABCB11 HSD17B1 HTT	7.13e-04	277	143	8	GO:1901617
GeneOntologyCellularComponent	endoplasmic reticulum membrane	RCE1 DIPK1C PTCHD3 CFTR AQP8 ATP10A SACM1L SGPP1 ORMDL1 ORMDL3 STS CHPT1 SCD DHCR7 PEX16 SARAF UNC93B1 TMED10 RFT1 TAP1 TM4SF20 ALG12 PIGO DUOXA2 CYBA	2.20e-06	1293	143	25	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	RCE1 DIPK1C PTCHD3 CFTR AQP8 ATP10A SACM1L SGPP1 ORMDL1 ORMDL3 STS CHPT1 SCD DHCR7 PEX16 SARAF UNC93B1 TMED10 RFT1 TAP1 TM4SF20 ALG12 PIGO DUOXA2 CYBA	2.39e-06	1299	143	25	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	RCE1 DIPK1C PTCHD3 CFTR AQP8 ATP10A SACM1L SGPP1 ORMDL1 ORMDL3 STS CHPT1 SCD DHCR7 PEX16 SARAF UNC93B1 TMED10 RFT1 TAP1 TM4SF20 ALG12 PIGO DUOXA2 CYBA	3.49e-06	1327	143	25	GO:0042175
GeneOntologyCellularComponent	intracellular canaliculus	AQP8 ABCB11	4.58e-04	5	143	2	GO:0046691
Domain	GPCR_Rhodpsn_7TM	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	7.16e-09	670	142	22	IPR017452
Domain	Olfact_rcpt	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	8.05e-09	393	142	17	IPR000725
Domain	7tm_1	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	8.64e-09	677	142	22	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	1.07e-08	685	142	22	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	1.25e-08	691	142	22	PS50262
Domain	GPCR_Rhodpsn	OPN3 OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 PTGER1 PTGFR OR14A16 OPRL1 OR10G7 OR10G4 GPR146 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	1.28e-08	692	142	22	IPR000276
Domain	ABC_membrane	CFTR ABCC5 ABCB8 ABCB11 TAP1	8.96e-07	24	142	5	PF00664
Domain	ABC_TM1F	CFTR ABCC5 ABCB8 ABCB11 TAP1	2.02e-06	28	142	5	PS50929
Domain	ABC1_TM_dom	CFTR ABCC5 ABCB8 ABCB11 TAP1	2.02e-06	28	142	5	IPR011527
Domain	Na-dicarboxylate_symporter	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	IPR001991
Domain	NA_DICARBOXYL_SYMP_1	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	PS00713
Domain	NA_DICARBOXYL_SYMP_2	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	PS00714
Domain	Na-dicarboxylate_symporter_CS	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	IPR018107
Domain	SDF	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	PF00375
Domain	-	SLC1A2 SLC1A5 SLC1A6	1.47e-05	7	142	3	1.10.3860.10
Domain	ABC_transporter_CS	CFTR ABCC5 ABCB8 ABCB11 TAP1	1.61e-05	42	142	5	IPR017871
Domain	ABC_tran	CFTR ABCC5 ABCB8 ABCB11 TAP1	3.12e-05	48	142	5	PF00005
Domain	ABC_TRANSPORTER_2	CFTR ABCC5 ABCB8 ABCB11 TAP1	3.12e-05	48	142	5	PS50893
Domain	ABC_TRANSPORTER_1	CFTR ABCC5 ABCB8 ABCB11 TAP1	3.45e-05	49	142	5	PS00211
Domain	Ptc/Disp	PTCHD3 PTCHD4 NPC1L1	3.50e-05	9	142	3	IPR003392
Domain	Patched	PTCHD3 PTCHD4 NPC1L1	3.50e-05	9	142	3	PF02460
Domain	ABC_transporter-like	CFTR ABCC5 ABCB8 ABCB11 TAP1	3.81e-05	50	142	5	IPR003439
Domain	Peptidase_M60_dom	TCAF2 TCAF1	5.74e-05	2	142	2	IPR031161
Domain	Peptidase_M60	TCAF2 TCAF1	5.74e-05	2	142	2	PF13402
Domain	M60-like	TCAF2 TCAF1	5.74e-05	2	142	2	SM01276
Domain	PEPTIDASE_M60	TCAF2 TCAF1	5.74e-05	2	142	2	PS51723
Domain	SSD	PTCHD3 PTCHD4 NPC1L1	1.16e-04	13	142	3	IPR000731
Domain	SSD	PTCHD3 PTCHD4 NPC1L1	1.16e-04	13	142	3	PS50156
Domain	Ion_channel_UNC-93	MFSD11 UNC93B1	1.71e-04	3	142	2	IPR010291
Domain	ORMDL	ORMDL1 ORMDL3	1.71e-04	3	142	2	PF04061
Domain	ORMDL	ORMDL1 ORMDL3	1.71e-04	3	142	2	IPR007203
Domain	UNC-93	MFSD11 UNC93B1	1.71e-04	3	142	2	PF05978
Domain	Bilac:Na_transpt	SLC10A3 SLC10A6	3.41e-04	4	142	2	IPR004710
Domain	ADEAMc	ADAR ADAD2	8.44e-04	6	142	2	SM00552
Domain	A_deamin	ADAR ADAD2	8.44e-04	6	142	2	PF02137
Domain	A_DEAMIN_EDITASE	ADAR ADAD2	8.44e-04	6	142	2	PS50141
Domain	A_deamin	ADAR ADAD2	8.44e-04	6	142	2	IPR002466
Domain	BilAc:Na_symport/Acr3	SLC10A3 SLC10A6	1.18e-03	7	142	2	IPR002657
Domain	SBF	SLC10A3 SLC10A6	1.18e-03	7	142	2	PF01758
Domain	Prostanoid_rcpt	PTGER1 PTGFR	1.56e-03	8	142	2	IPR008365
Domain	AIG1	GIMAP7 GIMAP8	1.56e-03	8	142	2	PF04548
Domain	G_AIG1	GIMAP7 GIMAP8	1.56e-03	8	142	2	IPR006703
Domain	G_AIG1	GIMAP7 GIMAP8	1.56e-03	8	142	2	PS51720
Domain	MIP_CS	AQP8 AQP1	2.48e-03	10	142	2	IPR022357
Domain	AdipoR/HlyIII-related	MMD ADIPOR2	3.02e-03	11	142	2	IPR004254
Domain	HlyIII	MMD ADIPOR2	3.02e-03	11	142	2	PF03006
Domain	Class_I_gatase-like	TCAF2 TCAF1	3.60e-03	12	142	2	IPR029062
Domain	AAA+_ATPase	CFTR ABCC5 ABCB8 ABCB11 TAP1	4.90e-03	144	142	5	IPR003593
Domain	AAA	CFTR ABCC5 ABCB8 ABCB11 TAP1	4.90e-03	144	142	5	SM00382
Domain	MIP	AQP8 AQP1	4.92e-03	14	142	2	PS00221
Domain	Dynein_HC_stalk	DNHD1 DNAH14	4.92e-03	14	142	2	IPR024743
Domain	MIP	AQP8 AQP1	4.92e-03	14	142	2	PF00230
Domain	MT	DNHD1 DNAH14	4.92e-03	14	142	2	PF12777
Domain	DHC_fam	DNHD1 DNAH14	5.65e-03	15	142	2	IPR026983
Domain	MIP	AQP8 AQP1	5.65e-03	15	142	2	IPR000425
Domain	-	AQP8 AQP1	5.65e-03	15	142	2	1.20.1080.10
Domain	Dynein_heavy_dom	DNHD1 DNAH14	5.65e-03	15	142	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH14	5.65e-03	15	142	2	PF03028
Domain	Aquaporin-like	AQP8 AQP1	5.65e-03	15	142	2	IPR023271
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.14e-09	417	103	18	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10G9 OR52K2	2.89e-09	389	103	17	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 HSD17B1 OR10G9 OR52K2	1.45e-07	636	103	19	M41834
Pathway	KEGG_ABC_TRANSPORTERS	CFTR ABCC5 ABCB8 ABCB11 TAP1	1.64e-05	44	103	5	M11911
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC36A4 CFTR ABCC5 AQP8 AQP1 SLC1A2 ATP10A ANKH SLC1A5 SLC1A6 SLC22A1 ABCB8 SLC10A6 TRPV6 ATP1A1	1.22e-04	681	103	15	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC36A4 CFTR ABCC5 AQP8 AQP1 SLC1A2 ATP10A ANKH SLC1A5 SLC1A6 SLC22A1 ABCB8 SLC10A6 TRPV6 ATP1A1	2.83e-04	736	103	15	M27287
Pubmed	The human olfactory receptor gene family.	OR13C5 OR4D10 OR4D9 OR4D1 OR4D11 OR14A16 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13C9 OR13A1 OR13C2 OR10AC1 OR10G9 OR52K2	1.29e-11	541	144	18	14983052
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR4D10 OR4D1 OR4D11 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13A1 OR10AC1 OR10G9 OR52K2	1.98e-09	340	144	13	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR4D10 OR4D1 OR4D11 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13A1 OR10AC1 OR10G9 OR52K2	2.20e-09	343	144	13	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR4D10 OR4D1 OR4D11 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13A1 OR10AC1 OR10G9 OR52K2	2.44e-09	346	144	13	14611657
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR4D10 OR4D1 OR4D11 OR10G7 OR10G4 OR51A7 OR52I2 OR52R1 OR52K1 OR13A1 OR10G9 OR52K2	2.05e-08	340	144	12	11875048
Pubmed	Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas.	CFTR AQP8 AQP1	2.77e-07	4	144	3	12801959
Pubmed	TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity.	TCAF2 TCAF1 TRPV6	2.77e-07	4	144	3	25559186
Pubmed	Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.	CFTR AQP8 AQP1	1.38e-06	6	144	3	28384265
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	OPRL1 GPR146 BNIP3L CHPT1 PEX16 SARAF ATP1A1 TMED10 SLC52A2 TAP1 MTCH1 GPRC5B HTT	7.17e-06	697	144	13	28298427
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	SLC1A5 SACM1L SCD SARAF UNC93B1 ATP1A1 TMED10 RFT1 TAP1 MTCH1 PIGO	8.01e-06	499	144	11	22810586
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C9 OR13C2	1.49e-05	12	144	3	12906860
Pubmed	Aquaporin-1 and 8 expression in the gallbladder mucosa might not be associated with the development of gallbladder stones in humans.	AQP8 AQP1	1.70e-05	2	144	2	26707370
Pubmed	Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR.	CFTR HTT	1.70e-05	2	144	2	27493027
Pubmed	Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients.	STS HSD17B1	1.70e-05	2	144	2	20151319
Pubmed	ORMDL proteins regulate ceramide levels during sterile inflammation.	ORMDL1 ORMDL3	1.70e-05	2	144	2	27313060
Pubmed	CHIP regulates skeletal development and postnatal bone growth.	COL10A1 AQP1	1.70e-05	2	144	2	31898815
Pubmed	CHD6 regulates the topological arrangement of the CFTR locus.	CFTR CHD6	1.70e-05	2	144	2	25631877
Pubmed	Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans.	TCAF2 TCAF1	1.70e-05	2	144	2	34433829
Pubmed	Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis.	ORMDL1 ORMDL3	1.70e-05	2	144	2	38715613
Pubmed	ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer.	ADAR SCD	1.70e-05	2	144	2	37208334
Pubmed	Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation.	SLC1A2 HTT	1.70e-05	2	144	2	12135980
Pubmed	Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema.	CFTR ATP1A1	1.70e-05	2	144	2	14555664
Pubmed	Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium.	AQP8 AQP1	1.70e-05	2	144	2	15859952
Pubmed	The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl- Channel.	CFTR AQP1	1.70e-05	2	144	2	30050452
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	AQP8 AQP1 SLC1A6 SLC22A1 IL2RB GPRC5B	3.04e-05	143	144	6	20424473
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCE1 SUSD6 SACM1L STS CHPT1 DHCR7 ROBO1 SARAF UNC93B1 ATP1A1 TMED10 RFT1 TAP1 ALG12 PIGO HTT	4.04e-05	1201	144	16	35696571
Pubmed	Phenotype analysis of aquaporin-8 null mice.	AQP8 AQP1	5.09e-05	3	144	2	15647389
Pubmed	m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.	AQP1 ANKH	5.09e-05	3	144	2	34737423
Pubmed	Evidence against functionally significant aquaporin expression in mitochondria.	AQP8 AQP1	5.09e-05	3	144	2	16624821
Pubmed	Corticotropin-releasing hormone stimulates estrogen biosynthesis in cultured human placental trophoblasts.	STS HSD17B1	5.09e-05	3	144	2	16467490
Pubmed	Involvement of aquaporins in a mouse model of rotavirus diarrhea.	AQP8 AQP1	5.09e-05	3	144	2	25160756
Pubmed	Developmental and TGF-beta-mediated regulation of Ank mRNA expression in cartilage and bone.	COL10A1 ANKH	5.09e-05	3	144	2	12056852
Pubmed	Estrogen formation in endometrial and cervix cancer cell lines: involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12).	STS HSD17B1	5.09e-05	3	144	2	18817841
Pubmed	Cyclic adenosine monophosphate regulation of aquaporin gene expression in human amnion epithelia.	AQP8 AQP1	5.09e-05	3	144	2	17636236
Pubmed	Escherichia coli alpha-hemolysin triggers shrinkage of erythrocytes via K(Ca)3.1 and TMEM16A channels with subsequent phosphatidylserine exposure.	CFTR AQP1	5.09e-05	3	144	2	20231275
Pubmed	Cardiac aquaporin expression in humans, rats, and mice.	AQP8 AQP1	5.09e-05	3	144	2	16582023
Pubmed	Significance and expression of aquaporin 1, 3, 8 in cervical carcinoma in Xinjiang Uygur women of China.	AQP8 AQP1	5.09e-05	3	144	2	22901156
Pubmed	ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.	ORMDL1 ORMDL3	5.09e-05	3	144	2	12093374
Pubmed	Steroid-converting enzymes in human ovarian carcinomas.	STS HSD17B1	5.09e-05	3	144	2	18723074
Pubmed	Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation.	ORMDL1 ORMDL3	5.09e-05	3	144	2	37316542
Pubmed	Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells.	ORMDL1 ORMDL3	5.09e-05	3	144	2	25395622
Pubmed	Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis.	ORMDL1 ORMDL3	5.09e-05	3	144	2	23066021
Pubmed	Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia.	SLC1A2 SLC1A6	5.09e-05	3	144	2	20958799
Pubmed	Links between L-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: evidence following inhibition with rottlerin.	SLC1A2 ATP1A1	5.09e-05	3	144	2	24095695
Pubmed	7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome.	RET DHCR7	5.09e-05	3	144	2	27334845
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	SEMA6B DNHD1 OTOR ADAMTS13 MAMDC4 ANKH ZDHHC24 PRRT3 SARAF MTCH1 TM4SF20 PIGO AMTN ERVFRD-1	6.36e-05	985	144	14	12975309
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	ABCC5 SLC1A2 SLC1A5 SLC22A1	6.54e-05	52	144	4	26590417
Pubmed	Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.	ORMDL1 ORMDL3 CHPT1 TBC1D1 STOML1 ABHD13 SARAF GPRC5B ERVFRD-1	8.12e-05	430	144	9	16303743
Pubmed	Systematic identification of pathological lamin A interactors.	AQP1 SACM1L ZDHHC24 ORMDL1 ORMDL3 BNIP3L TAP1 TM4SF20	8.59e-05	337	144	8	24623722
Pubmed	Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis.	STS HSD17B1	1.02e-04	4	144	2	17454161
Pubmed	Orm family proteins mediate sphingolipid homeostasis.	ORMDL1 ORMDL3	1.02e-04	4	144	2	20182505
Pubmed	Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter.	SLC1A2 SLC1A6	1.02e-04	4	144	2	9379843
Pubmed	Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice.	SLC1A2 SLC1A6	1.02e-04	4	144	2	29463856
Pubmed	Differential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with interleukin-6 production.	SLC22A1 ABCB11	1.02e-04	4	144	2	23929842
Pubmed	Optimization of RNA isolation from human ocular tissues and analysis of prostanoid receptor mRNA expression using RT-PCR.	PTGER1 PTGFR	1.02e-04	4	144	2	11951086
Pubmed	In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia.	STS HSD17B1	1.02e-04	4	144	2	18467089
Pubmed	Common variations in 4p locus are related to male completed suicide.	TBC1D1 HTT	1.02e-04	4	144	2	19115052
Pubmed	Potential sites of prostaglandin actions in the periimplantation mouse uterus: differential expression and regulation of prostaglandin receptor genes.	PTGER1 PTGFR	1.02e-04	4	144	2	9116135
Pubmed	Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes.	AQP8 AQP1	1.02e-04	4	144	2	29626438
Pubmed	Contribution of prostanoid FP receptor and prostaglandins in transient inflammatory ocular hypertension.	PTGER1 PTGFR	1.02e-04	4	144	2	30038227
Pubmed	Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta.	AQP8 AQP1	1.02e-04	4	144	2	32542408
Pubmed	[Expression of aquaporins 1, 3, 8, 9 mRNA in human fetal membranes].	AQP8 AQP1	1.02e-04	4	144	2	17545093
Pubmed	The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice.	ORMDL1 ORMDL3	1.02e-04	4	144	2	31880535
Pubmed	Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.	COL10A1 GRIA3 SLC10A3	1.16e-04	23	144	3	8464923
Pubmed	Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.	ABCC5 ABCB8 ABCB11	1.16e-04	23	144	3	10708515
Pubmed	Crispr-Cas9 engineered osteogenesis imperfecta type V leads to severe skeletal deformities and perinatal lethality in mice.	COL10A1 ANKH IFITM5	1.32e-04	24	144	3	29174564
Pubmed	Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.	CFTR RET HTT	1.50e-04	25	144	3	8889551
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	CFTR ABCC5 SLC22A1 ABCB8 ABCB11 TAP1	1.60e-04	193	144	6	19343046
Pubmed	Aquaporin expression patterns in the developing mouse salivary gland.	AQP8 AQP1	1.69e-04	5	144	2	20121927
Pubmed	SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease.	RET ROBO1	1.69e-04	5	144	2	25786906
Pubmed	Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.	ABCB8 ABCB11	1.69e-04	5	144	2	11829140
Pubmed	Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells.	GIMAP7 GIMAP8	1.69e-04	5	144	2	11964296
Pubmed	Structural insights into the mechanism of GTPase activation in the GIMAP family.	GIMAP7 GIMAP8	1.69e-04	5	144	2	23454188
Pubmed	Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells.	SLC1A2 SLC1A6	1.69e-04	5	144	2	9129177
Pubmed	The Expression of Water and Ion Channels in Diffuse Alveolar Damage Is Not Dependent on DAD Etiology.	AQP1 ATP1A1	1.69e-04	5	144	2	27835672
Pubmed	c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.	NFKBID IL2RB	1.69e-04	5	144	2	28652399
Pubmed	A novel human endogenous retroviral protein inhibits cell-cell fusion.	SLC1A5 ERVFRD-1	1.69e-04	5	144	2	23492904
Pubmed	Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.	PTGER1 PTGFR	1.69e-04	5	144	2	8253813
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	DDX47 PPAN ABCC5 SLC1A5 SCD DHCR7 STOML1 ROBO1 SARAF ATP1A1 TMED10 RFT1 PIGO	1.74e-04	952	144	13	38569033
Pubmed	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.	DNHD1 ORC3 CHD6	1.89e-04	27	144	3	17525332
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	OPN3 ABCC5 SACM1L ORMDL1 TRMT6 ORMDL3 STOML1 ROBO1 SARAF ALG12 PIGO	2.13e-04	719	144	11	35337019
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	PPAN MFSD11 NOL10 DHCR7 ABCB8 RFT1 HTT	2.45e-04	296	144	7	34186245
Pubmed	Ontogeny of erythroid gene expression.	AQP8 AQP1	2.53e-04	6	144	2	23243273
Pubmed	Evidence of efficient stop codon readthrough in four mammalian genes.	OPRL1 SACM1L	2.53e-04	6	144	2	25013167
Pubmed	ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis.	ORMDL1 ORMDL3	2.53e-04	6	144	2	25691431
Pubmed	Chromosomal localization of the human prostanoid receptor gene family.	PTGER1 PTGFR	2.53e-04	6	144	2	7759114
Pubmed	Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).	RET TBC1D1	2.53e-04	6	144	2	26572137
Pubmed	An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.	IL2RB TAP1	2.53e-04	6	144	2	17664294
Pubmed	Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice.	AQP8 AQP1	2.53e-04	6	144	2	20957496
Pubmed	The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships.	SLC10A3 SLC10A6	2.53e-04	6	144	2	16541252
Pubmed	Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.	OR52I2 OR52K1 OR52K2	3.46e-04	33	144	3	17350283
Pubmed	Role of aquaporin water channels in kidney and lung.	AQP8 AQP1	3.53e-04	7	144	2	9822113
Pubmed	Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes.	COL10A1 ANKH	3.53e-04	7	144	2	22421045
Pubmed	Defining the membrane proteome of NK cells.	RCE1 DDX47 NUP85 ADAR SLC1A5 SCD DHCR7 PEX16 ABHD13 IL2RB TAP1 ALG12 PIGO CYBA	3.68e-04	1168	144	14	19946888
Pubmed	Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36.	GIMAP7 GIMAP8	4.69e-04	8	144	2	11814688
Pubmed	Prostanoid receptors: structures, properties, and functions.	PTGER1 PTGFR	4.69e-04	8	144	2	10508233
Pubmed	Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.	PTGER1 PTGFR	4.69e-04	8	144	2	20566843
Pubmed	Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia.	PTGER1 PTGFR	4.69e-04	8	144	2	15834430
Pubmed	The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut.	PTGER1 PTGFR	4.69e-04	8	144	2	11927615
Pubmed	Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.	PTGER1 PTGFR	4.69e-04	8	144	2	17496729
Interaction	SLC22A9 interactions	SLC25A46 SACM1L SGPP1 ORMDL1 ORMDL3 CHPT1 ABCB8 TAP1 MTCH1	8.37e-08	120	130	9	int:SLC22A9
Interaction	AQP6 interactions	SLC25A46 AQP1 DEFB103A SACM1L ZDHHC24 ORMDL1 ORMDL3 SCD PEX16 SLC35E4 UNC93B1 RFT1 TAP1	2.25e-07	330	130	13	int:AQP6
Interaction	SLC10A1 interactions	SLC25A46 CFTR SACM1L ORMDL1 ORMDL3 PEX16 SLC35E4 TAP1	1.18e-06	121	130	8	int:SLC10A1
Interaction	GPR182 interactions	MMS22L TCAF1 ORC3 SACM1L SGPP1 MROH1 CHPT1 SCD ABCB8 UNC93B1 RFT1 TAP1 PIGO HTT	1.47e-06	455	130	14	int:GPR182
Interaction	SLC35C2 interactions	SACM1L ORMDL1 ORMDL3 SCD SLC10A6 PEX16 UNC93B1 TAP1	1.80e-06	128	130	8	int:SLC35C2
Interaction	SPPL2B interactions	RCE1 CHPT1 ABCB8 UNC93B1 ATP1A1 RFT1 SLC52A2 MPPE1 MTCH1 PIGO	2.79e-06	233	130	10	int:SPPL2B
Interaction	SCN3B interactions	ABCC5 DEFB103A SACM1L ORMDL1 SCD ABCB8 PEX16 SLC35E4 MTCH1	1.05e-05	214	130	9	int:SCN3B
Interaction	TCTN3 interactions	DDX47 CFTR ORMDL3 CHPT1 SCD DHCR7 UNC93B1 ATP1A1 RFT1 TAP1 ADIPOR2	1.11e-05	334	130	11	int:TCTN3
Interaction	MFSD14B interactions	SLC25A46 SACM1L ZDHHC24 ORMDL1 SCD PEX16	1.30e-05	80	130	6	int:MFSD14B
Interaction	ERGIC3 interactions	SLC25A46 DEFB103A SGPP1 ORMDL1 ORMDL3 CHPT1 SCD PEX16 UNC93B1 RFT1 TAP1	1.31e-05	340	130	11	int:ERGIC3
Interaction	SLC10A6 interactions	SLC25A46 CFTR SACM1L ORMDL1 SCD SLC10A6 PEX16 TAP1	2.14e-05	179	130	8	int:SLC10A6
Interaction	AQP3 interactions	SLC25A46 ADAR ORMDL1 ORMDL3 ABCB8 PEX16 UNC93B1 RFT1 TAP1	2.53e-05	239	130	9	int:AQP3
Interaction	GPR12 interactions	ORMDL1 CHPT1 ABCB8 PEX16 TAP1 CYBA	3.09e-05	93	130	6	int:GPR12
Interaction	VAPB interactions	SLC25A46 CFTR RET SACM1L SCD SLC22A1 DHCR7 UNC93B1 TMED10 RFT1 TAP1 HTT	4.77e-05	464	130	12	int:VAPB
Interaction	CMKLR1 interactions	SLC25A46 SACM1L SGPP1 ROBO1 UNC93B1 GPRC5B	4.93e-05	101	130	6	int:CMKLR1
Interaction	FAM209A interactions	OTOR AQP1 SACM1L ORMDL1 ORMDL3 SCD PEX16 SLC52A2 MMD	5.03e-05	261	130	9	int:FAM209A
Interaction	RIMKLB interactions	PTGFR OR10G4 OR10G9	5.53e-05	12	130	3	int:RIMKLB
Interaction	CYB5R3 interactions	SLC1A5 SACM1L DHCR7 SLC10A6 PEX16 UNC93B1 TMED10 MTCH1 ADIPOR2 AMTN	6.93e-05	338	130	10	int:CYB5R3
Interaction	ALG9 interactions	GRIA3 KCNK16 STS CHPT1 MPPE1	1.41e-04	77	130	5	int:ALG9
Cytoband	11p15.4	DNHD1 OR51A7 OR52I2 OR52R1 OR52K1 OR52K2	4.29e-05	200	144	6	11p15.4
Cytoband	9q31.1	OR13C5 OR13C9 OR13C2	2.95e-04	41	144	3	9q31.1
Cytoband	7q35	TCAF2 TCAF1 OR10AC1	7.04e-04	55	144	3	7q35
Cytoband	16p12	AQP8 GPRC5B	8.67e-04	14	144	2	16p12
GeneFamily	Solute carriers	SLC25A46 SLC36A4 SLC6A16 SLC10A3 SLC1A2 SLC1A5 SLC1A6 SLC22A1 SLC10A6 SLC35E4 SLC52A2 MTCH1	2.07e-06	395	101	12	752
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C9 OR13A1 OR13C2	7.49e-06	23	101	4	162
GeneFamily	ATP binding cassette subfamily B	ABCB8 ABCB11 TAP1	2.70e-05	11	101	3	806
GeneFamily	Olfactory receptors, family 52	OR52I2 OR52R1 OR52K1 OR52K2	1.60e-04	49	101	4	165
GeneFamily	Olfactory receptors, family 10	OR10G7 OR10G4 OR10AC1 OR10G9	5.07e-04	66	101	4	157
GeneFamily	GTPases, IMAP	GIMAP7 GIMAP8	8.46e-04	8	101	2	580
GeneFamily	Adenosine deaminases acting on RNA	ADAR ADAD2	8.46e-04	8	101	2	1303
GeneFamily	Prostaglandin (prostanoid) receptors	PTGER1 PTGFR	1.08e-03	9	101	2	207
GeneFamily	Progestin and adipoQ receptor family	MMD ADIPOR2	1.64e-03	11	101	2	930
GeneFamily	ATP binding cassette subfamily C	CFTR ABCC5	2.32e-03	13	101	2	807
GeneFamily	Aquaporins	AQP8 AQP1	2.69e-03	14	101	2	305
GeneFamily	Olfactory receptors, family 4	OR4D10 OR4D9 OR4D1 OR4D11	5.93e-03	129	101	4	151
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	MFSD11 ABCC5 SLC10A3 AQP1 ATP10A ANKH SGPP1 ZDHHC24 SCD ATP1A1 TMED10 SLC52A2 ALG12 PIGO GPRC5B HTT	7.08e-07	681	139	16	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	MFSD11 ABCC5 SLC10A3 AQP1 ATP10A ANKH SGPP1 ZDHHC24 SCD ATP1A1 TMED10 SLC52A2 ALG12 PIGO GPRC5B HTT	1.07e-06	703	139	16	MM1055
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP	SIDT1 BBS1 ABCC5 GRIA3 PTGER1 BNIP3L CLEC11A SARAF ATP1A1	1.22e-06	199	139	9	M4521
Coexpression	GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP	NUP85 ORC3 ATP10A SMYD4 TRMT6 DHCR7 SLC52A2 TAP1	1.20e-05	200	139	8	M4830
Coexpression	WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK	SLC25A46 SLC1A5 ORMDL3 CHPT1 SCD ADIPOR2 GPRC5B	1.39e-05	147	139	7	MM1316
Coexpression	WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK	SLC25A46 SLC1A5 ORMDL3 CHPT1 SCD ADIPOR2 GPRC5B	1.45e-05	148	139	7	M2420
Coexpression	GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN	ADAR ATP10A HMCN2 STOML1 UNC93B1 TAP1 SECTM1	8.45e-05	195	139	7	M4292
Coexpression	AFFAR_YY1_TARGETS_UP	COL10A1 CFTR ABCC5 GRIA3 SLC1A6 HSD17B1 TAP1	9.59e-05	199	139	7	M1466
Coexpression	GSE30083_SP3_VS_SP4_THYMOCYTE_DN	MAN1C1 SIDT1 ANKH MROH1 IL2RB MPPE1 MMD	9.89e-05	200	139	7	M5037
Coexpression	GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_DN	MFSD11 LAG3 GIMAP7 GIMAP8 UNC93B1 IL2RB TAP1	9.89e-05	200	139	7	M6474
Coexpression	GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	SLC36A4 BNIP3L SCD UNC93B1 TAP1 MMD CYBA	9.89e-05	200	139	7	M6242
Coexpression	GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP	RCE1 SEMA6B OPN3 BNIP3L SCD PEX16 MMD	9.89e-05	200	139	7	M3413
Coexpression	GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN	NFKBID AQP1 ADAR SLC1A5 GPR146 TRMT6 GIMAP8	9.89e-05	200	139	7	M6095
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAN1C1 CFTR MFSD6L RET SCD DHCR7 ROBO1 GPRC5B	1.57e-07	184	144	8	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAG3 SIDT1 GIMAP7 GIMAP8 SCD SARAF IL2RB FCMR	1.78e-07	187	144	8	66cf67c76067e4ba8c09c110adfa0ccc0d1c5ee9
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 STOML1 ROBO1 UNC93B1 IL2RB FCMR	1.74e-06	176	144	7	11067b649fe21ac2bb328829ecadc2f64c2c10aa
ToppCell	droplet-Spleen-nan-21m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 STOML1 ROBO1 UNC93B1 IL2RB FCMR	1.74e-06	176	144	7	130238f0707541c511f479619c4f7a3593ef0ebf
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAN1C1 CFTR MFSD6L RET ROBO1 AMTN GPRC5B	1.95e-06	179	144	7	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SEMA6B SIDT1 GIMAP7 AQP1 GPR146 ADAD2 TAP1	2.60e-06	187	144	7	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAG3 GIMAP7 GIMAP8 IL2RB MMD CFAP46	6.39e-06	140	144	6	a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP7 SLC1A5 ZDHHC24 SCD IL2RB FCMR	1.37e-05	160	144	6	1cb6f42b68c9e41e8edae0de8f0d8371c4620b04
ToppCell	facs-Liver-Liver_non-hepato/SCs\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP7 SLC1A5 ZDHHC24 SCD IL2RB FCMR	1.37e-05	160	144	6	ebefde92db400cbe68d9ce31545a0308e0afbde1
ToppCell	Immune_cells-B_cell\|World / Lineage and Cell class	NFKBID GIMAP7 SCD UNC93B1 FCMR CYBA	1.52e-05	163	144	6	3a02465de7c2f7cea227e289fb082a1fb6400301
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCAF2 LAG3 OR4D1 SDR42E2 ABHD13 IL2RB	1.74e-05	167	144	6	9c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	COL10A1 CFTR KCNK16 GLP2R NPC1L1 DUOXA2	1.80e-05	168	144	6	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAN1C1 CFTR MFSD6L RET ROBO1 GPRC5B	1.80e-05	168	144	6	6a233045638cb83dab64789b996b7598c325001e
ToppCell	facs-Heart-LV-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 NFKBID GIMAP7 GIMAP8 IL2RB FCMR	1.93e-05	170	144	6	2491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RET PTCHD4 PTGFR SLC10A6 NKAIN3 DUOXA2	1.93e-05	170	144	6	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	droplet-Spleen-nan-21m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 STOML1 ROBO1 UNC93B1 CYBA	2.06e-05	172	144	6	3dc02709c2a6be2155576e5c34e1b0b3ae19b061
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAG3 GIMAP7 ZP1 DEFB124 HEATR9 IL2RB	2.13e-05	173	144	6	42272af45547422ef85e35f4a4c7d269e9ed7a8a
ToppCell	facs-Marrow-T-cells\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 GIMAP8 SCD IL2RB FCMR	2.13e-05	173	144	6	806f94f5c3ac836ddffc389d3c2cd7e4da7a608d
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAG3 GIMAP7 ZP1 DEFB124 HEATR9 IL2RB	2.20e-05	174	144	6	5c69447261c5aa309a24882656da90655728d637
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A ANKH GIMAP8 MMD FCMR	2.35e-05	176	144	6	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	PPAN LAG3 SLC1A5 SCD HSD17B1 HTT	2.35e-05	176	144	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A ANKH GIMAP8 MMD FCMR	2.35e-05	176	144	6	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	droplet-Marrow-BM-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 AQP1 ORMDL3 GIMAP8 IL2RB	2.42e-05	177	144	6	650095a17e1a39caea74a6e89646565b9332af5d
ToppCell	droplet-Marrow-BM-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 AQP1 ORMDL3 GIMAP8 IL2RB	2.42e-05	177	144	6	d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 IL2RB MMD FCMR	2.42e-05	177	144	6	f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCell	LPS-antiTNF-Lymphocytic_NKT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 IL2RB MMD FCMR	2.58e-05	179	144	6	ecea75c568911ff56939c9f67ab901497bd4356c
ToppCell	LPS-IL1RA-Lymphocytic_NKT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 IL2RB MMD FCMR	2.58e-05	179	144	6	5ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SIDT1 GIMAP7 AQP1 GPR146 GIMAP8 HMCN2	2.66e-05	180	144	6	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CCP110 SUSD6 SACM1L GIMAP8 CLEC11A HTT	3.01e-05	184	144	6	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 GIMAP8 SCD IL2RB FCMR	3.01e-05	184	144	6	b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCell	mild_COVID-19-CD8+_T_naive\|mild_COVID-19 / disease group, cell group and cell class (v2)	MAN1C1 GIMAP7 ORMDL3 CLEC11A SARAF FCMR	3.40e-05	188	144	6	60d27014e5f9e562efe2a602482ea1d07efd0331
ToppCell	LPS_only-Lymphocytic_NKT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 IL2RB MMD FCMR	3.40e-05	188	144	6	bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCell	mild_COVID-19-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	MAN1C1 GIMAP7 ORMDL3 CLEC11A SARAF FCMR	3.40e-05	188	144	6	ddfb1c64305825fb0bc23819aa001bfc2ac4c2b2
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAN1C1 CFTR MFSD6L RET DHCR7 GPRC5B	3.60e-05	190	144	6	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B AQP1 ANKH SLC10A6 GPRC5B DUOXA2	3.60e-05	190	144	6	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B AQP1 ANKH SLC10A6 GPRC5B DUOXA2	3.60e-05	190	144	6	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B AQP1 ANKH SLC10A6 GPRC5B DUOXA2	3.60e-05	190	144	6	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	NS-critical-d_07-13-Lymphoid-Treg\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LAG3 GIMAP7 ANKH GIMAP8 IL2RB FCMR	3.82e-05	192	144	6	cd34defac6565d34db507918e791b09c79f7d1f8
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAN1C1 GIMAP7 ORMDL3 ROBO1 SARAF FCMR	3.93e-05	193	144	6	d371403b51281a6e37652fa8dc1b2dd81d2ab371
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAN1C1 GIMAP7 ORMDL3 ROBO1 SARAF FCMR	3.93e-05	193	144	6	6436d3bfce02d137b76e5c4c8b2fe27974c57c99
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAN1C1 GIMAP7 ORMDL3 ROBO1 SARAF FCMR	3.93e-05	193	144	6	3cde93bbfc1ae6fb586ae6b7aaa6ed8b5eee28a4
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAN1C1 GIMAP7 ORMDL3 ROBO1 SARAF FCMR	3.93e-05	193	144	6	d755dc6de4fbd4d8f5d8a88aac497e7b9e8b89de
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAG3 GIMAP7 SACM1L ORMDL1 IL2RB FCMR	4.16e-05	195	144	6	4b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B AQP1 GIMAP8 HMCN2 ADIPOR2 GPRC5B	4.16e-05	195	144	6	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	Severe-Lymphoid-T-Treg\|Severe / Condition, Lineage, Cell class and cell subclass	TCAF2 LAG3 GIMAP7 ORMDL3 IL2RB FCMR	4.28e-05	196	144	6	29d4db6816fead2ad9136ef824e0775463b02159
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAG3 SIDT1 GIMAP7 IL2RB TAP1 FCMR	4.41e-05	197	144	6	927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAG3 SIDT1 GIMAP7 IL2RB TAP1 FCMR	4.41e-05	197	144	6	3e09158507df08c08e08613ce23617206280c911
ToppCell	Severe_COVID-19-T/NK-CD4+_T_2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	LAG3 GIMAP7 ORMDL3 SARAF IL2RB FCMR	4.53e-05	198	144	6	c8c9343c19198b6534f8f07e74405e29b3a164bf
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CFTR MFSD6L RET SCD DHCR7 GPRC5B	4.53e-05	198	144	6	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_Exhausted\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAG3 GIMAP7 ORMDL3 SARAF IL2RB FCMR	4.53e-05	198	144	6	a5f5c0b42ae43ba48a7e4f06c4ad179b2244d941
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LAG3 GIMAP7 ORMDL3 SARAF IL2RB FCMR	4.53e-05	198	144	6	93773b1abbf46b39e320d628077bf94958b872a4
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	LAG3 GIMAP7 ORMDL3 SARAF IL2RB FCMR	4.53e-05	198	144	6	812ffe7369bf83ae5071970934c8831611db9557
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_Exhausted-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAG3 GIMAP7 ORMDL3 SARAF IL2RB FCMR	4.53e-05	198	144	6	bb99db3e04d547248ea66953c2f8dd55c530461c
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Transitional_AT2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MAN1C1 CFTR MFSD6L RET SCD DHCR7	4.66e-05	199	144	6	cd581d7330b471431ef427f8a4f5be553f70e068
ToppCell	distal-Endothelial-Artery-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GIMAP7 AQP1 MED24 GIMAP8 ATP1A1 ADIPOR2	4.66e-05	199	144	6	3788f3218356aaaa10684e48d63757037f8a3a3c
ToppCell	VE-CD4-CD8_2\|VE / Condition, Cell_class and T cell subcluster	MAN1C1 GIMAP7 SLC1A2 ADAD2 PRRT3	4.81e-05	122	144	5	6745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 GIMAP8 SLC35E4 IL2RB CFAP46	5.19e-05	124	144	5	05e114fcfe84cfc8d92978a4eda6db4d8a616e0e
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 MMD FCMR	6.04e-05	128	144	5	c2045f052cc713e52312eb015825711576fcb6c5
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-AT1-AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMS22L HMCN2 SCD PRRT3 ERVFRD-1	6.04e-05	128	144	5	082b3dc312b033c9b21cf73499009a1dc049ee2b
ToppCell	URO-Lymphocyte-T_NK-CD8_TCM\|URO / Disease, Lineage and Cell Type	TCAF2 COL10A1 GIMAP7 SLC1A6 ZP1	9.55e-05	141	144	5	53aef819f505238011f8a3202445f31055791d05
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL10A1 PKD1L3 ADAD2 FCMR	1.08e-04	76	144	4	355a6793e2828728da62357bd2250735b0fd76b1
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL10A1 PKD1L3 ADAD2 FCMR	1.08e-04	76	144	4	2c304b41c04a567874126df25b15d8ee2ad2b6d9
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAG3 SIDT1 GIMAP7 HEATR9 IL2RB	1.20e-04	148	144	5	7cb4865a1e9522e24f9c14799568b67172bd99dc
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OPN3 PTCHD4 ATP10A MMD FCMR	1.24e-04	149	144	5	4b44108c40376a6b73258df40d2424e68f991383
ToppCell	Lymphoid-Lymphoid-B_cells\|Lymphoid / shred on cell class and cell subclass (v4)	SCD CHD6 UNC93B1 FCMR CYBA	1.28e-04	150	144	5	5ebf6b4b9b029422a4676ba09a6a9225bd25db47
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 IL2RB FCMR CYBA	1.44e-04	154	144	5	ee03b386d28a524084eaf1c0091f7389daa34250
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFTR PTGER1 NPC1L1 TRPV6 CYBA	1.44e-04	154	144	5	9316732964a819a8e935a952faa3823109f90b77
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 IL2RB FCMR CYBA	1.44e-04	154	144	5	3fa6f77ad2c30ec24b9b904e2732ec5b419dff5b
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAG3 GIMAP7 SGPP1 IL2RB HTT	1.49e-04	155	144	5	5687416773809b8c478567bc54310af102b3029a
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 GIMAP8 IL2RB TAP1	1.53e-04	156	144	5	39aa3adbee9f04cdc0055487d393edfa515e062b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 GIMAP8 IL2RB TAP1	1.53e-04	156	144	5	a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCell	IPF-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	MAN1C1 CFTR MFSD6L RET GPRC5B	1.63e-04	158	144	5	67adf625a959444762d32268b3b7441f6f8b3b8c
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 GIMAP8 SARAF IL2RB	1.68e-04	159	144	5	94bc6ab248a8f02ccbc0facd24e0c7e9fda687d2
ToppCell	Immune_cells-NK_cells\|World / Lineage and Cell class	SIDT1 NFKBID GIMAP7 GIMAP8 IL2RB	1.78e-04	161	144	5	3ef2e15b06286d94c18b71626aed456f681cc77b
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e-Excitatory_Neuron.Sc17a7.Sema3e-Nnat_(Layer_6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS13 DNAH14 SLC22A1 DUOXA2	1.82e-04	87	144	4	7518ca56d626619d9706505169a85f1850105608
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAG3 GIMAP7 SACM1L IL2RB FCMR	1.88e-04	163	144	5	453e0bb292baca2938d24582fedfd6a8bb1e78e9
ToppCell	facs-GAT-Fat-24m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP7 SMYD4 GIMAP8 HEATR9 IL2RB	1.88e-04	163	144	5	e58863a462cc504bced627f004a47890ee2307ce
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP8 SCD DHCR7 ABCB11 ADIPOR2	1.99e-04	165	144	5	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFTR MFSD6L RET TBC1D1 DHCR7	1.99e-04	165	144	5	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 NFKBID GIMAP7 GIMAP8 IL2RB	2.16e-04	168	144	5	18c266162a879544c0103d9dff0270af68964f9e
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 PTCHD4 TRPV6 IL2RB	2.16e-04	168	144	5	1254c66f0cd53ef3b913933c0b0648d091da07e9
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFTR MFSD6L RET TBC1D1 DHCR7	2.16e-04	168	144	5	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MMS22L SIDT1 GIMAP7 MAMDC4 IL2RB	2.16e-04	168	144	5	6c758eb120faf06ff72d157b495e399191c79ec9
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 GIMAP8 HEATR9 IL2RB	2.16e-04	168	144	5	110c3c7c322e04a684a19c2b5434a502279fd000
ToppCell	facs-Marrow-T-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP7 SCD IL2RB FCMR CYBA	2.16e-04	168	144	5	0ece1e196d17c0f276424abd5cb43d528f40224b
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 NFKBID GIMAP7 GIMAP8 IL2RB	2.16e-04	168	144	5	cb1506cd43a4f36f9024cc9b8e5319365498d244
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 GIMAP8 HEATR9 IL2RB	2.16e-04	168	144	5	735d30cfda1889740bdeb43e39330a52e8f4d599
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 ZP1 HEATR9 IL2RB	2.23e-04	169	144	5	18ba8fc2ba8838484d3b223428cd41568e2ccb10
ToppCell	droplet-Marrow-BM-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP7 AQP1 ANKH IL2RB GPRC5B	2.23e-04	169	144	5	8e7a30eb546fc6fa184ebb76f54b74b278005a84
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 STOML1 UNC93B1 FCMR	2.23e-04	169	144	5	d44fc49056799dfc70a3c7d538c210d88ffded05
ToppCell	droplet-Lung-nan-21m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 ZP1 HEATR9 IL2RB	2.23e-04	169	144	5	47a63afd80cb7ba2258ba57d3084d8b2a7bc4e8d
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 TRPV6 IL2RB MPPE1	2.23e-04	169	144	5	8028622ff362d70d1002e65a74ade46ea7f1f13f
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAG3 GIMAP7 GIMAP8 IL2RB FCMR	2.29e-04	170	144	5	26178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCell	droplet-Marrow-BM-30m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 GIMAP7 GIMAP8 SARAF IL2RB	2.29e-04	170	144	5	f8defd260dadd202692282e834ed7f38193eb553
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBID GIMAP7 STOML1 UNC93B1 FCMR	2.29e-04	170	144	5	53fd50c9a27d47662fbcbd7e9e9837f72ac448c5
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAG3 GIMAP7 GIMAP8 SARAF IL2RB	2.29e-04	170	144	5	d74fbd995a8a37fc237f7147d398357b811d6452
ToppCell	Severe-Lymphoid-T-\|Severe / Condition, Lineage, Cell class and cell subclass	TCAF2 LAG3 GIMAP7 IL2RB FCMR	2.29e-04	170	144	5	5788e1158fde036937d41708e9db3222ca351eb1
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SIDT1 GIMAP7 GIMAP8 SARAF IL2RB	2.29e-04	170	144	5	8e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR PTGFR ATP10A GPRC5B OSGIN1	2.35e-04	171	144	5	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP7 ATP10A GIMAP8 MMD FCMR	2.35e-04	171	144	5	539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
Drug	ZK110841	RET PTGER1 PTGFR HTT	1.77e-06	15	140	4	CID005311503
Disease	bronchiectasis (is_implicated_in)	CFTR TAP1	2.02e-05	2	133	2	DOID:9563 (is_implicated_in)
Disease	glycosyltransferase-like protein LARGE1 measurement	CHPT1 PEX16	1.20e-04	4	133	2	EFO_0802578
Disease	Choledochal Cyst, Type II	CFTR AQP1	2.00e-04	5	133	2	C1257796
Disease	Choledochal Cyst, Type III	CFTR AQP1	2.00e-04	5	133	2	C1257797
Disease	Choledochal Cyst, Type IV	CFTR AQP1	2.00e-04	5	133	2	C1257798
Disease	Choledochal Cyst, Type V	CFTR AQP1	2.00e-04	5	133	2	C1257799
Disease	Choledochal Cyst, Type I	CFTR AQP1	2.00e-04	5	133	2	C0009439
Disease	Choledochal Cyst	CFTR AQP1	2.00e-04	5	133	2	C0008340
Disease	episodic ataxia type 6 (implicated_via_orthology)	SLC1A5 SLC1A6	2.99e-04	6	133	2	DOID:0050994 (implicated_via_orthology)
Disease	neuropathy (implicated_via_orthology)	SLC25A46 MED24	2.99e-04	6	133	2	DOID:870 (implicated_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	GRIA3 SLC1A2 SLC1A5 SLC1A6 HTT	5.19e-04	145	133	5	DOID:1289 (implicated_via_orthology)
Disease	Autosomal Recessive Polycystic Kidney Disease	CFTR AQP1	7.11e-04	9	133	2	C0085548
Disease	cathepsin F measurement	ZDHHC24 CHPT1	7.11e-04	9	133	2	EFO_0022038
Disease	cystic fibrosis (implicated_via_orthology)	CFTR ABCB11	7.11e-04	9	133	2	DOID:1485 (implicated_via_orthology)
Disease	sleep duration, low density lipoprotein cholesterol measurement	PKD1L3 SLC22A1 NPC1L1 HTT	7.79e-04	91	133	4	EFO_0004611, EFO_0005271
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	CFTR AQP1	1.08e-03	11	133	2	DOID:0110861 (biomarker_via_orthology)
Disease	Hirschsprung's disease (implicated_via_orthology)	RET MED24	1.29e-03	12	133	2	DOID:10487 (implicated_via_orthology)
Disease	cholestasis (biomarker_via_orthology)	CFTR ADAMTS13 ABCB11	1.42e-03	49	133	3	DOID:13580 (biomarker_via_orthology)
Disease	gastric ulcer (implicated_via_orthology)	CFTR PTGER1	1.77e-03	14	133	2	DOID:10808 (implicated_via_orthology)
Disease	congenital disorder of glycosylation type I (implicated_via_orthology)	RFT1 ALG12	2.04e-03	15	133	2	DOID:0050570 (implicated_via_orthology)
Disease	hyperinsulinism (biomarker_via_orthology)	SCD ADIPOR2	2.04e-03	15	133	2	DOID:2018 (biomarker_via_orthology)
Disease	von Willebrand factor measurement	OR13C5 ADAMTS13 GIMAP7	2.08e-03	56	133	3	EFO_0004629
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ADAMTS13 SCD ADIPOR2	3.19e-03	65	133	3	DOID:0080208 (biomarker_via_orthology)
Disease	apolipoprotein B measurement	MAN1C1 BBS1 PKD1L3 ZDHHC24 SLC22A1 NPC1L1 ABCB11 HTT OSGIN1	3.19e-03	663	133	9	EFO_0004615
Disease	citrulline measurement	GLP2R HMCN2	3.63e-03	20	133	2	EFO_0009777

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSFLLGQVIPLAHTG	nan	71	Q8NBF4
LPLIVTFHLYGGIIL	ABHD13	31	Q7L211
HLLPALVLFLAGSSG	MAMDC4	6	Q6UXC1
LLLRNLGFTAIPLHG	DDX47	281	Q9H0S4
LLFLHLDSGVPQGVT	EPG5	1086	Q9HCE0
LGHAIHGLLVLPLIY	SLC1A5	311	Q15758
LGLGGALLAHLVSPL	ADAD2	406	Q8NCV1
FIVRTLLLHPAIFGL	CFTR	131	P13569
SGAHLNPAVTLGLLL	AQP1	71	P29972
LARVHILLALVLSPG	CFAP46	1301	Q8IYW2
LHGIAQPGVLLIFGT	ABCB11	71	O95342
LQPALAHGLALGLVI	AQP8	66	O94778
LIIHSLFPGGILPTS	AMTN	126	Q6UX39
LLLAVPHFGAGLLHI	DNHD1	396	Q96M86
IEGAVLIFLPGLAHI	DHX29	866	Q7Z478
QLSTPHAVGVLLLGL	DHCR7	331	Q9UBM7
IIFIATTNLLGLLPH	MT-ATP6	76	P00846
LLTHAVPGLLSPGLI	DACH2	196	Q96NX9
PIVTIALLTFLLHLG	ATP10A	1206	O60312
AGGILHLELLVAVGP	ADAMTS13	76	Q76LX8
PLLLGLLVAVATVHL	ALG12	11	Q9BV10
VFLGLGLSGIIPTLH	ADIPOR2	281	Q86V24
LLFLPGLVAVCAVHG	OTOR	6	Q9NRC9
PLAGLHLSPVLLGTF	RFT1	461	Q96AA3
GGFVHSIVQISLLLP	OR4D11	151	Q8NGI4
PILGNFLHIIVVILG	NKAIN3	36	Q8N8D7
LLTAFILTGLPHAPG	OR10G7	6	Q8NGN6
PVLFLLLLGVHLATL	OR10AC1	26	Q8NH08
LVTAFILTGLPHAPG	OR10G4	6	Q8NGN3
VLHVAATYGLPGVLL	NFKBID	121	Q8NI38
LGIPLNVIFLNHLGT	KCNK16	131	Q96T55
GLLLYIGHLSELPSV	MMS22L	176	Q6ZRQ5
HFQLSVLLAPTILGG	HMCN2	2536	Q8NDA2
VILAENGFLPIHLLG	ATP1A1	871	P05023
AVLHLLLSVPAGFLL	CYBA	91	P13498
SVALSLLGEILLHPF	MFSD6L	406	Q8IWD5
GFLVVLTLTHFGLLA	MPPE1	366	Q53F39
VLRAVFFLVLGLLGH	GRIA3	11	P42263
FLFIRTGHLIGPVLC	RCE1	246	Q9Y256
LFAVFIALLPILGHR	PTGFR	161	P43088
ILFIEVAPAGPLLLH	NUP85	151	Q9BW27
LFLLIGIPGLEHAHI	OR51A7	11	Q8NH64
FVVSIHSGLAGLAPL	SLC10A3	131	P09131
AGHVIPGALVLRLYT	PTGER1	86	P34995
LGNHSLGLPLITALV	PDZD3	26	Q86UT5
APGALPAGHLLLFLI	LAG3	441	P18627
PAGHLLLFLILGVLS	LAG3	446	P18627
LENLGLTHLIGSPFL	NOL10	381	Q9BSC4
GNGTLILISILDPHL	OR13C5	41	Q8NGS8
GNGTLILISILDPHL	OR13C2	41	Q8NGS9
GRNPVVLLGILVHFI	MFSD11	306	O43934
VSALVPFHNLGLLIG	MROH1	956	Q8NDA8
GLLHIVLLSIPFFSV	ORMDL1	31	Q9P0S3
AFLIVPAIVGSALLH	MMD	36	Q15546
SPVGLHFLFLLGTLG	GPRC5B	91	Q9NZH0
HPVSFILLGIPGLES	OR52R1	11	Q8NGF1
GGFVHSIAQISLLLP	OR4D9	151	Q8NGE8
LGLLHGLVFLPVILS	NPC1L1	1276	Q9UHC9
VAVGPLVILFSVLHI	ABCC5	1016	O15440
LFLGCLVVPLGVIAH	OPN3	206	Q9H1Y3
HAAGFSVPLLIVILV	DUOXA2	16	Q1HG44
LPSRVGALHGVLYVL	HTT	2776	P42858
IPLLGVHEILFSFIT	GLP2R	391	O95838
LGLQGALLTHFLQPI	ADAR	1046	P55265
SEIFLRGIHGPFLII	CHD6	501	Q8TD26
LSGILQAGLIHPVTG	CHD6	2256	Q8TD26
AVLLLPFGVHLSLIE	HSD17B1	171	P14061
AAVLGVILVLAIHPG	SLC1A2	131	P43004
IIGLIIHGGIFLPLI	SLC1A2	321	P43004
LFLVALLVLGHVPSG	DEFB124	6	Q8NES8
HLLVGLSGAFGFIIL	IL2RB	246	P14784
APSLHALLLVIAIGH	GIMAP8	91	Q8ND71
PSLFLSHVLALGLGI	BNIP3L	191	O60238
LIASLVVLPYLGVHG	ANKH	411	Q9HCJ1
IRFHGVAILSPLLNI	CCP110	36	O43303
VIVGLFLHAGIVLPL	SLC1A6	346	P48664
LVPVLSLHIGLARAL	DNAH14	16	Q0VDD8
GLVTLCFGALFLLPH	MAN1C1	31	Q9NR34
PPLLLLGLVVTGALH	IFITM5	96	A6NNB3
GLLALALHFLGLQPL	SDR42E2	401	A6NKP2
VAGLVLSALAPVHLL	GPR146	71	Q96CH1
VVQGLGPTFKLTLHL	BBS1	491	Q8NFJ9
PIFGILGTIHLVAGN	SACM1L	56	Q9NTJ5
VGLVALTGLAYALPH	SLC22A1	246	O15245
PLLLGAVALVHGVGL	PRRT3	571	Q5FWE3
LFLFLVPVPGHGGII	DEFB103A	11	P81534
LPSGFPLHTDILGLL	FUZ	286	Q9BT04
VLAAALLLRAHPGVL	DIPK1C	36	Q0P6D2
VVSGFGLLLHIGVPF	PTCHD3	426	Q3KNS1
GLLLHIGVPFVIIVA	PTCHD3	431	Q3KNS1
GGFVHSIVQLALILP	OR4D1	151	Q15615
VFGVSLVLVLIGSHP	OSGIN1	386	Q9UJX0
LVLVLIGSHPDLSFL	OSGIN1	391	Q9UJX0
GLLHIVLLSIPFVSV	ORMDL3	31	Q8N138
LVTAFILTGLPHAPG	OR10G9	6	Q8NGN4
LAHVVLILRLPFSGP	OR2A1;	156	Q8NGT9
VLITLAITFNPGLHA	OR13A1	61	Q8NGR1
LFLLLPLSAFHGVKG	IZUMO3	6	Q5VZ72
LHEFPLILIFGIATS	ORC3	241	Q9UBD5
LILIFGIATSPIIIH	ORC3	246	Q9UBD5
LHPHLLVLGVAVVLA	ABCB8	141	Q9NUT2
GNGTLILISILDPHL	OR13C9	41	Q8NGT0
SHGAFLPLGLKVTIV	OPRL1	41	P41146
PHLLVVLFLSTGFIA	OR14A16	241	Q8NHC5
SFLLVGIPGLQSSHL	OR52I2	41	Q8NH67
PAVFLLVGIPGLEHL	OR52K1	11	Q8NGK4
PTAFLLVGIPGLEHL	OR52K2	11	Q8NGK3
GGFVHSIVQISLLLP	OR4D10	151	Q8NGI6
FLLQLLADHVPGVGL	PEX16	301	Q9Y5Y5
VALGAGVTALSHPLL	MTCH1	86	Q9NZJ7
EEGLLGFFVGLIPHL	MTCH1	246	Q9NZJ7
GFFVGLIPHLLGDVV	MTCH1	251	Q9NZJ7
ADLTILLGHPISPIF	SLC6A16	596	Q9GZN6
PLGGLLLTLGVFCHI	SMYD4	336	Q8IYR2
LGLHLFLLTAGPALG	SARAF	16	Q96BY9
SQLLVHGALAFPLGL	TCAF1	236	Q9Y4C2
SQLLVHGALAFPLGL	TCAF2	236	A6NFQ2
SAIHSIGGIQVLFPL	NBEA	491	Q8NFP9
SLGGHTLILIPEVLL	PRR23B	91	Q6ZRT6
GPHAIVLVLLLGRYT	GIMAP7	91	Q8NHV1
VLILTFFLVIHPLGN	PTCHD4	671	Q6ZW05
LVLLGHILPGLLTDS	MED24	781	O75448
PARPVLTHLLVALFG	SLC52A2	6	Q9HAB3
AATHLVGFPVLLATV	PKD1L3	1551	Q7Z443
APFIIIGLHLALGIF	SGPP1	291	Q9BX95
LGLLHVPLGVFFSLL	STS	206	P08842
SGLLTPLHLEGLVQF	TAP1	491	Q03518
VASVGHGVFLPLVIL	SUSD6	16	Q92537
HGVFLPLVILCTLLG	SUSD6	21	Q92537
LIHFSVFLGLLLVGI	TM4SF20	186	Q53R12
LLGALVVPQLLGFGH	CLEC11A	6	Q9Y240
GTSVLSPGLHIGLII	CHPT1	261	Q8WUD6
PFLLLVSLNLVHGVF	COL10A1	6	Q03692
PRAGLSLFLHLILAV	C11orf94	11	C9JXX5
LLLLLGGAHGLFPEE	SEMA6B	16	Q9H3T3
VAGAGVHLLLTFILF	UNC93B1	406	Q9H1C4
VLLLPAVALVLGFGV	ZP1	606	P60852
LAFPGHVSQALGTLL	SECTM1	6	Q8WVN6
AIHFIPLLAGLGILA	ERVFRD-1	351	P60508
LFLLGPRLVLAISFH	TMED10	21	P49755
LLSLIFPTVLHGVLH	SLC25A46	261	Q96AG3
HGLISFLGFLLLLVT	STOML1	56	Q9UBI4
VAGPLGVTHFLILSK	PPAN	76	Q9NQ55
NLGHVLLGFLFLLIV	SIDT1	501	Q9NXL6
FGLQLVGSLPVHSLT	TBC1D1	21	Q86TI0
GFHILIPTILGLFLL	FCMR	251	O60667
LGVLGIRSPQVFHLL	HEATR9	426	A2RTY3
FGQTILGGPFHVLII	TRPV6	456	Q9H1D0
LLTISFIFPLIGHVT	SLC10A6	226	Q3KNW5
LLHLGALYGITLIPT	SCD	81	O00767
LLPSGSLFFLRIVHG	ROBO1	121	Q9Y6N7
GFVLGVDLLHIFPLE	MRM2	106	Q9UI43
AGVLLLHFNVSVLPV	RET	386	P07949
AAGVLLHVSVLLGPA	ZDHHC24	146	Q6UX98
GLIVASRFHPTPLLL	TRMT6	371	Q9UJA5
SFLLLHLLAAGIPVT	PIGO	866	Q8TEQ8
FTVHGFGRPLLLSAL	SLC35E4	71	Q6ICL7
LGPISLVFIGIISVH	SLC36A4	91	Q6YBV0