Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondinucleotide repeat insertion binding

MSH2 MSH3

1.25e-052712GO:0032181
GeneOntologyMolecularFunctionsingle guanine insertion binding

MSH2 MSH3

3.73e-053712GO:0032142
GeneOntologyMolecularFunctiondinucleotide insertion or deletion binding

MSH2 MSH3

3.73e-053712GO:0032139
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THSD4 COL4A4 DSPP LAMA3 COL6A5 EDIL3

5.54e-05188716GO:0005201
GeneOntologyMolecularFunctionguanine/thymine mispair binding

MSH2 MSH3

7.44e-054712GO:0032137
GeneOntologyMolecularFunctionsingle base insertion or deletion binding

MSH2 MSH3

7.44e-054712GO:0032138
GeneOntologyMolecularFunctionDNA insertion or deletion binding

MSH2 MSH3

1.85e-046712GO:0032135
GeneOntologyMolecularFunctioncentromeric DNA binding

MSH2 MSH3

2.59e-047712GO:0019237
GeneOntologyMolecularFunctionoxidized purine DNA binding

MSH2 MSH3

5.51e-0410712GO:0032357
GeneOntologyMolecularFunctionoxidized DNA binding

MSH2 MSH3

6.72e-0411712GO:0032356
GeneOntologyMolecularFunctionmismatched DNA binding

MSH2 MSH3

1.10e-0314712GO:0030983
GeneOntologyBiologicalProcesspositive regulation of anion channel activity

TCAF1 ABCB1

3.40e-053702GO:1901529
GeneOntologyBiologicalProcesspositive regulation of anion transmembrane transport

TCAF1 ABCB1

3.40e-053702GO:1903961
GeneOntologyBiologicalProcesspositive regulation of monoatomic anion transport

TCAF1 ABCB1

6.78e-054702GO:1903793
GeneOntologyCellularComponentMutSbeta complex

MSH2 MSH3

1.14e-052712GO:0032302
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THSD4 COL4A4 DSPP FCN1 LAMA3 NCAM1 COL6A5 EGFLAM EDIL3

7.45e-05530719GO:0062023
GeneOntologyCellularComponentextracellular matrix

THSD4 COL4A4 DSPP FCN1 LAMA3 NCAM1 COL6A5 EGFLAM EDIL3

3.67e-04656719GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THSD4 COL4A4 DSPP FCN1 LAMA3 NCAM1 COL6A5 EGFLAM EDIL3

3.75e-04658719GO:0030312
GeneOntologyCellularComponentsite of double-strand break

SMCHD1 POLH EPC1 INTS3

3.89e-04101714GO:0035861
GeneOntologyCellularComponentmismatch repair complex

MSH2 MSH3

6.13e-0411712GO:0032300
GeneOntologyCellularComponentcell-cell junction

NRAP ATP7B MYLK DSC1 DSC2 LAMA3 NCAM1 ABCB1

8.65e-04591718GO:0005911
GeneOntologyCellularComponent9+2 non-motile cilium

STRC STRCP1

1.01e-0314712GO:0097732
GeneOntologyCellularComponentkinocilium

STRC STRCP1

1.01e-0314712GO:0060091
GeneOntologyCellularComponentsite of DNA damage

SMCHD1 POLH EPC1 INTS3

1.22e-03137714GO:0090734
Domain-

MSH2 MSH3

3.79e-0536723.30.420.110
DomainDNA_mismatch_repair_MutS-lik_N

MSH2 MSH3

3.79e-053672IPR007695
DomainMutS_I

MSH2 MSH3

3.79e-053672PF01624
DomainMutS_II

MSH2 MSH3

7.57e-054672PF05188
DomainHIN_200

IFI16 PYHIN1

7.57e-054672PS50834
DomainHIN

IFI16 PYHIN1

7.57e-054672PF02760
DomainHIN200/IF120x

IFI16 PYHIN1

7.57e-054672IPR004021
DomainDNA_mmatch_repair_MutS_con_dom

MSH2 MSH3

7.57e-054672IPR007860
DomainMutS_IV

MSH2 MSH3

1.26e-045672PF05190
DomainMutS_III

MSH2 MSH3

1.26e-045672PF05192
DomainDNA_mismatch_repair_MutS_C

MSH2 MSH3

1.26e-045672IPR000432
DomainMUTSd

MSH2 MSH3

1.26e-045672SM00533
DomainMUTSac

MSH2 MSH3

1.26e-045672SM00534
DomainMutS_V

MSH2 MSH3

1.26e-045672PF00488
DomainDNA_mismatch_repair_MutS_core

MSH2 MSH3

1.26e-045672IPR007696
DomainDNA_mismatch_repair_MutS_clamp

MSH2 MSH3

1.26e-045672IPR007861
DomainDNA_MISMATCH_REPAIR_2

MSH2 MSH3

1.26e-045672PS00486
DomainDesmosomal_cadherin

DSC1 DSC2

2.63e-047672IPR009122
DomainCadherin_pro

DSC1 DSC2

2.63e-047672PF08758
DomainCadherin_pro_dom

DSC1 DSC2

3.50e-048672IPR014868
DomainCadherin_pro

DSC1 DSC2

3.50e-048672SM01055
DomainVWA

CLCA1 CACNA2D2 COL6A5

1.07e-0356673PF00092
DomainEGF

TIE1 LAMA3 EGFLAM EDIL3 GPR179

1.55e-03235675SM00181
Domain-

CLCA1 CACNA2D2 COL6A5

2.38e-03746733.40.50.410
Domainfn3

MYLK TIE1 NCAM1 EGFLAM

2.73e-03162674PF00041
DomainDAPIN

IFI16 PYHIN1

2.80e-0322672PS50824
DomainPYRIN

IFI16 PYHIN1

2.80e-0322672PF02758
DomainDAPIN

IFI16 PYHIN1

2.80e-0322672IPR004020
DomainPYRIN

IFI16 PYHIN1

2.80e-0322672SM01289
DomainVWFA

CLCA1 CACNA2D2 COL6A5

3.19e-0382673PS50234
DomainVWA

CLCA1 CACNA2D2 COL6A5

3.42e-0384673SM00327
DomainCollagen

COL4A4 FCN1 COL6A5

3.53e-0385673IPR008160
DomainCollagen

COL4A4 FCN1 COL6A5

3.53e-0385673PF01391
DomainCadherin_cytoplasmic-dom

DSC1 DSC2

3.61e-0325672IPR000233
DomainCadherin_C

DSC1 DSC2

3.61e-0325672PF01049
DomainFN3

MYLK TIE1 NCAM1 EGFLAM

4.39e-03185674SM00060
DomainCatenin_binding_dom

DSC1 DSC2

4.84e-0329672IPR027397
Domain-

DSC1 DSC2

4.84e-03296724.10.900.10
DomainVWF_A

CLCA1 CACNA2D2 COL6A5

5.41e-0399673IPR002035
DomainATP_grasp_subdomain_2

TTLL6 MCCC1

5.51e-0331672IPR013816
DomainFN3

MYLK TIE1 NCAM1 EGFLAM

5.68e-03199674PS50853
DomainFN3_dom

MYLK TIE1 NCAM1 EGFLAM

6.74e-03209674IPR003961
DomainCadherin_CS

DSC1 DSC2 PCDH11X

7.07e-03109673IPR020894
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A4 DSPP LAMA3 NCAM1 COL6A5

9.35e-0676535M27219
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FASN GAPVD1 ILF3 DSC1 CACNA2D2 SYNE1 SMCHD1 DDX18 PABPC4 EIF5 CASP7 APOB MSH2 MSH3 NHP2

1.51e-071425711530948266
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

SP1 FASN GAPVD1 SMCHD1 MSH2 MSH3 TAF1 INTS3

4.00e-0733271832786267
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

THSD4 COL4A4 LAMA3 EGFLAM EDIL3

6.16e-077971518757743
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

FASN ILF3 DSC1 SMCHD1 MYL6B DDX18 PABPC4 EIF5 LAMA3 MSH2 SPATS2 IFI16 EDIL3

1.40e-061257711336526897
Pubmed

Conformational trapping of mismatch recognition complex MSH2/MSH3 on repair-resistant DNA loops.

MSH2 MSH3

4.11e-06271221960445
Pubmed

DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse.

POLH MSH2

4.11e-06271217190840
Pubmed

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.

SP1 IFI16

4.11e-06271231175045
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

4.11e-06271234910522
Pubmed

The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.

SP1 IFI16

4.11e-06271222291595
Pubmed

Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.

MSH2 MSH3

4.11e-06271221128252
Pubmed

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha.

MSH2 MSH3

4.11e-0627129677427
Pubmed

Mismatch recognition protein MutSbeta does not hijack (CAG)n hairpin repair in vitro.

MSH2 MSH3

4.11e-06271219525234
Pubmed

Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.

EGFLAM GPR179

4.11e-06271237490546
Pubmed

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops.

MSH2 MSH3

4.11e-06271222179786
Pubmed

Differential synthesis of type 1 and type 2 desmocollin mRNAs in human stratified epithelia.

DSC1 DSC2

4.11e-0627128507556
Pubmed

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA.

MSH2 MSH3

4.11e-0627128805365
Pubmed

Effective oligonucleotide-mediated gene disruption in ES cells lacking the mismatch repair protein MSH3.

MSH2 MSH3

4.11e-06271216437133
Pubmed

(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.

MSH2 MSH3

4.11e-06271216025128
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

4.11e-06271211687802
Pubmed

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.

MYLK DSC2 APOB MSH2

5.80e-065771423788249
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FASN GAPVD1 ILF3 SYNE1 SMCHD1 MYL6B DDX18 PABPC4 MSH2 EDIL3 ABCB1

6.96e-061024711124711643
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SP1 ILF3 SMCHD1 DDX18 EPC1 MSH2 MSH3 MCCC1 CHRAC1 INTS3 NHP2 IFI16

1.13e-051294711230804502
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

1.23e-05371230801007
Pubmed

DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication.

MSH2 MSH3

1.23e-05371221957315
Pubmed

Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators.

SP1 TAF1

1.23e-0537127824954
Pubmed

Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head.

APOB ABCB1

1.23e-05371218696186
Pubmed

MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta.

MSH2 MSH3

1.23e-05371220154325
Pubmed

The influence of desmocollin 1-3 expression on prognosis after curative resection of colorectal liver metastases.

DSC1 DSC2

1.23e-05371223975055
Pubmed

Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer.

MSH2 MSH3

1.23e-0537129774676
Pubmed

Compositionally different desmosomes in the various compartments of the human hair follicle.

DSC1 DSC2

1.23e-0537129810708
Pubmed

Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.

DSC1 DSC2

1.23e-0537129389456
Pubmed

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions.

MSH2 MSH3

1.23e-05371210545954
Pubmed

MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells.

MSH2 MSH3

1.23e-05371222941650
Pubmed

Crosstalk between MSH2-MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair.

MSH2 MSH3

1.23e-05371227546332
Pubmed

Transcription promotes contraction of CAG repeat tracts in human cells.

MSH2 MSH3

1.23e-05371216388310
Pubmed

MutSbeta exceeds MutSalpha in dinucleotide loop repair.

MSH2 MSH3

1.23e-05371220160730
Pubmed

Desmocollin switching in colorectal cancer.

DSC1 DSC2

1.23e-05371217088906
Pubmed

Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients.

MSH2 MSH3

1.23e-05371228093084
Pubmed

Activation of human MutS homologs by 8-oxo-guanine DNA damage.

MSH2 MSH3

1.23e-05371211756455
Pubmed

NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription.

ILF3 ACRV1

1.23e-05371217942973
Pubmed

The nucleotide binding dynamics of human MSH2-MSH3 are lesion dependent.

MSH2 MSH3

1.23e-05371219377479
Pubmed

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern.

MSH2 MSH3

1.23e-05371210662804
Pubmed

[Genetic analysis for prevention of steroid-induced osteonecrosis of the femoral head].

APOB ABCB1

1.23e-05371217548929
Pubmed

Structural and functional characterization of the mouse multidrug resistance gene family.

SP1 ABCB1

1.23e-0537121980424
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

FASN ILF3 MYLK SMCHD1 DDX18 PABPC4 EIF5 INTS3 NHP2

1.43e-0571171933022573
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

TTLL6 DSPP SYNE1 POLH DENND3

1.54e-0515271534299191
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

CLCA1 DSC2 CACNA2D2 SMCHD1 MYL6B EPC1 TAF1 DENND3

1.69e-0555271810737800
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

FASN ILF3 COQ8A PABPC4 MSH2 MCCC1

2.03e-0527271625315684
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CNNM2 RAP1GDS1 ATP7B MYL6B PABPC4 FASTKD1 PEX14 SPATS2 YIPF3

2.26e-0575471933060197
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

2.46e-05471218849963
Pubmed

A novel function of apolipoprotein E: upregulation of ATP-binding cassette transporter A1 expression.

SP1 APOB

2.46e-05471221779326
Pubmed

The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF.

SP1 TAF1

2.46e-05471212498690
Pubmed

cis-Regulatory control of Mesp1 expression by YY1 and SP1 during mouse embryogenesis.

SP1 EDIL3

2.46e-05471226384464
Pubmed

The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair.

MSH2 MSH3

2.46e-05471224013230
Pubmed

The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells.

POLH MSH2

2.46e-05471221855803
Pubmed

Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.

MSH2 MSH3

2.46e-05471217142234
Pubmed

Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues.

SP1 ABCB1

2.46e-05471223133566
Pubmed

Sp1 coordinately regulates de novo lipogenesis and proliferation in cancer cells.

SP1 FASN

2.46e-05471219621387
Pubmed

Transcriptional repression of protein kinase Calpha via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation.

SP1 ABCB1

2.46e-05471215563462
Pubmed

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks.

MSH2 MSH3

2.46e-05471219468048
Pubmed

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.

MSH2 MSH3

2.46e-0547128942985
Pubmed

The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.

MSH2 MSH3

2.46e-05471222289650
Pubmed

Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter.

SP1 FASN

2.46e-05471222331133
Pubmed

The mammalian PYHIN gene family: phylogeny, evolution and expression.

IFI16 PYHIN1

2.46e-05471222871040
Pubmed

Association between genetic polymorphisms in DNA mismatch repair-related genes with risk and prognosis of head and neck squamous cell carcinoma.

MSH2 MSH3

2.46e-05471225598504
Pubmed

Association of IFI200 gene polymorphisms with susceptibility to systemic lupus erythematosus.

IFI16 PYHIN1

2.46e-05471220595294
Pubmed

Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.

APOB ABCB1

2.46e-05471232243098
Pubmed

Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis.

SP1 CASP7

2.46e-05471210103059
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GAPVD1 DSC2 DDX18 PABPC4 PEX14 NCAM1 APOB MCCC1 ADCY9

2.86e-0577771935844135
Pubmed

hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis.

MSH2 MSH3

4.09e-05571210029069
Pubmed

The interaction of DNA mismatch repair proteins with human exonuclease I.

MSH2 MSH3

4.09e-05571211427529
Pubmed

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6.

MSH2 MSH3

4.09e-05571216728433
Pubmed

Nomenclature of the desmosomal cadherins.

DSC1 DSC2

4.09e-0557128486729
Pubmed

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors.

MSH2 MSH3

4.09e-05571217715146
Pubmed

MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1.

MSH2 MSH3

4.09e-05571237140056
Pubmed

Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.

DSC1 DSC2

4.09e-05571222438068
Pubmed

Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.

CACNA2D2 ABCB1

4.09e-05571223402298
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

STRC STRCP1

4.09e-05571224920589
Pubmed

The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation.

IFI16 PYHIN1

4.09e-05571214757431
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

FASN ILF3 SMCHD1 PABPC4 PEX14 MCCC1 ABCB1

5.97e-0548471731995728
Pubmed

Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.

MSH2 MSH3

6.13e-05671211498787
Pubmed

hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.

MSH2 MSH3

6.13e-05671211809883
Pubmed

DNA mismatch repair and cancer.

MSH2 MSH3

6.13e-05671211223406
Pubmed

Pathology of mouse models of intestinal cancer: consensus report and recommendations.

MSH2 MSH3

6.13e-05671212612914
Pubmed

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors.

IFI16 PYHIN1

6.13e-05671223045604
Pubmed

Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1.

MSH2 MSH3

6.13e-05671220188637
Pubmed

The Mismatch-Binding Factor MutSβ Can Mediate ATR Activation in Response to DNA Double-Strand Breaks.

MSH2 MSH3

6.13e-05671226212458
Pubmed

Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse.

DSC1 DSC2

6.13e-0567129404003
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SYNE1 SMCHD1 DDX18 SPATS2 NHP2 IFI16

6.15e-0533271625693804
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A4 TIE1 LAMA3

7.63e-054071327068110
Pubmed

Tight junction regulation by morphine and HIV-1 tat modulates blood-brain barrier permeability.

MYLK ABCB1

8.57e-05771218574677
Pubmed

Three novel collagen VI chains with high homology to the alpha3 chain.

LAMA3 COL6A5

8.57e-05771218276594
Pubmed

A family of protein-deglutamylating enzymes associated with neurodegeneration.

MYLK TTLL6

8.57e-05771221074048
Pubmed

Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.

MSH2 MSH3

8.57e-05771219115210
Pubmed

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.

MSH2 MSH3

8.57e-05771218723338
Pubmed

Common variants in mismatch repair genes and risk of invasive ovarian cancer.

MSH2 MSH3

8.57e-05771216774946
Pubmed

Common variants in mismatch repair genes and risk of colorectal cancer.

MSH2 MSH3

8.57e-05771218364438
Pubmed

IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

GAPVD1 TCAF1 RAP1GDS1 PABPC4 EIF5

9.17e-0522171531950832
Pubmed

Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.

FASN APOB TAF1

9.49e-054371318722179
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

FASN TCAF1 RAP1GDS1 PDPR DSC1 DDX18 EIF5 PEX14 MCCC1 INTS3 NHP2

9.75e-051367711132687490
Cytoband15q15.3

STRC STRCP1

6.91e-042571215q15.3
Cytoband18q12.1

DSC1 DSC2

7.48e-042671218q12.1
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

IFI16 PYHIN1

7.76e-055512995
GeneFamilyMutS homologs|PWWP domain containing

MSH2 MSH3

7.76e-0555121026
GeneFamilyDesmosomal cadherins

DSC1 DSC2

1.62e-0475121188
GeneFamilyFibronectin type III domain containing

MYLK TIE1 NCAM1 EGFLAM

1.07e-03160514555
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

IFI16 PYHIN1

2.25e-0325512994
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

RAP1GDS1 ARMC2

6.54e-0343512409
GeneFamilyCollagens

COL4A4 COL6A5

7.46e-0346512490
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYLK ALPK3 NCAM1

1.06e-02161513593
CoexpressionGSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP

ILF3 DSC1 POLH DDX18 PABPC4 INTS3

8.40e-06176716M7103
CoexpressionNABA_CORE_MATRISOME

THSD4 COL4A4 DSPP LAMA3 COL6A5 EGFLAM EDIL3

8.63e-06270717MM17057
CoexpressionNABA_CORE_MATRISOME

THSD4 COL4A4 DSPP LAMA3 COL6A5 EGFLAM EDIL3

9.72e-06275717M5884
CoexpressionLUCAS_HNF4A_TARGETS_UP

ATP7B DSC2 ATXN7L1 ABCB1

1.88e-0558714M11410
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A4 MYLK CACNA2D2 LAMA3 EDIL3 DENND3

4.80e-071837166821dca076318115d360ff426eb1218cfe104063
ToppCellCOVID-NK-|COVID / Condition, Cell_class and T cell subcluster

COL4A4 TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

5.62e-07188716fabdd68a9734d35e75e1f4a4bfd5c531cfc099f1
ToppCellCOVID-NK|COVID / Condition, Cell_class and T cell subcluster

COL4A4 TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

5.62e-071887160beaa671611110a11e46156f54f5202cc24967a4
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERICH3 NRAP COQ8A CACNA2D2 PABPC4 ALPK3

6.35e-07192716f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERICH3 NRAP COQ8A CACNA2D2 PABPC4 ALPK3

6.35e-071927161a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ERICH3 SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

6.75e-07194716a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FASN CACNA2D2 SYNE1 LAMA3 MCCC1 ADCY9

6.75e-0719471697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ERICH3 SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

6.75e-071947160abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

ERICH3 SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

7.38e-07197716a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 COL4A4 CACNA2D2 LAMA3 MCCC1 ADCY9

7.83e-071997165cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / disease group, cell group and cell class

ERICH3 SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

7.83e-07199716bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

TIE1 SMCHD1 CASP7 EGFLAM IFI16 EDIL3

8.06e-07200716be55cef682ba87250dad97689332c8820b3a7420
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 TTLL6 ACRV1 DNAH9 FABP6

6.30e-0616371543194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellileum|World / shred on tissue and cell subclass

DSC2 CASP7 APOB ABCB1 FABP6

7.73e-061707159f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

1.05e-051817159c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK PCDH11X NCAM1 BCHE APOB

1.05e-05181715b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.08e-051827158ccffcbae28c374fd4161fb0d4cf2c49fae557f6
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL4A4 NCAM1 IFI16 ABCB1 PYHIN1

1.19e-05186715e0eeef2b9e06324354c5a11a4c6d4c98546f32af
ToppCellfacs-Heart-Unknown-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.23e-051877150ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.23e-05187715362e56426a568423a81e8a30e3ecf99b76135843
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.23e-05187715c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.26e-0518871590dc0e15798d0b984518ad58c7e416e30aff687a
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP COQ8A PTPRN ALPK3 BCHE

1.26e-051887154db566f3f708e66730aa9e16f4d73d91dc534177
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.26e-05188715f63dfd076ced81013918363282ae25cbbd8948ae
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.26e-051887150554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP COQ8A PTPRN ALPK3 BCHE

1.26e-051887156704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.29e-05189715a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.29e-05189715efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

1.29e-051897153e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A CACNA2D2 ALPK3

1.36e-05191715c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A CACNA2D2 ALPK3

1.36e-05191715715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.39e-051927150bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TIE1 PCDH11X LAMA3 IFI16

1.39e-0519271556b021c297a21dff357531f21e2464f85186106d
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSC2 COQ8A PABPC4 ALPK3

1.39e-05192715d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ERICH3 SYNE1 ARMC2 DNAH9 FABP6

1.43e-05193715ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellnormal-na-Lymphocytic_NK-NK_bright-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

1.46e-05194715dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCellnormal-na-Lymphocytic_NK-NK_bright|normal / PBMC cell types (v2) per disease, treatment status, and sex

TIE1 SYNE1 NCAM1 ABCB1 PYHIN1

1.46e-051947158c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TIE1 PCDH11X LAMA3 IFI16

1.50e-051957156bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

1.50e-05195715609732e83ab7fc3ba7dace66f5a17e46557fd6d1
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.50e-051957159990440bda7fac5d00ef80444fab07459be625e1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

1.54e-051967155b5cf6f70534661d694f47359b6595b4580876c3
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.54e-05196715418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.54e-05196715581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

1.54e-051967158e1ed30256a031bb90dac1f167e074c68efbed74
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.54e-051967156beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.54e-05196715c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellSevere-Lymphoid-NK-NK|Severe / Condition, Lineage, Cell class and cell subclass

ERICH3 SYNE1 NCAM1 ABCB1 PYHIN1

1.58e-05197715d5b94f9f73e9d050245841b19b046242a32c6258
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 TTLL6 SYNE1 ARMC2 DNAH9

1.58e-0519771574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

1.58e-05197715550cce374332c49893bcf4ce4b7dceb7f5fe26aa
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK SYNE1 ALPK3 BCHE EDIL3

1.58e-05197715ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 SYNE1 NCAM1 IFI16 PYHIN1

1.61e-051987150e918e9db9b884f5328d438e90efe065e27266ee
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 SYNE1 NCAM1 IFI16 PYHIN1

1.61e-05198715ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERICH3 SYNE1 NCAM1 IFI16 PYHIN1

1.61e-05198715fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK SYNE1 ALPK3 BCHE EDIL3

1.61e-05198715c12e7511628db819a52959bb68580e27c00c2e41
ToppCellsevere_COVID-19-NK|World / disease group, cell group and cell class (v2)

ERICH3 SYNE1 NCAM1 ABCB1 PYHIN1

1.61e-0519871536b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERICH3 SYNE1 NCAM1 IFI16 PYHIN1

1.61e-051987151ef3a6bd681c223eed58300348adfef89df5563c
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK NCAM1 BCHE COL6A5 EDIL3

1.61e-051987157582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK SYNE1 ALPK3 BCHE EDIL3

1.61e-0519871522e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 IFI16 ABCB1 PYHIN1

1.61e-051987155607e36f393cb399fcc2504502498453fd32d96b
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 COL4A4 CACNA2D2 LAMA3 MCCC1

1.65e-051997155f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 COL4A4 CACNA2D2 LAMA3 MCCC1

1.65e-05199715725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 COL4A4 CACNA2D2 LAMA3 MCCC1

1.65e-051997158587bd98de7767a575088afbea07a1feb4516b9b
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A4 MYLK PCDH11X LAMA3 EGFLAM

1.65e-051997150cdbedf09ec72734b86ddab3fec562e066afed92
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

ERICH3 SYNE1 NCAM1 IFI16 PYHIN1

1.65e-05199715edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ERICH3 SYNE1 NCAM1 ABCB1 PYHIN1

1.65e-05199715df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ERICH3 SYNE1 NCAM1 ABCB1 PYHIN1

1.65e-05199715ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellControl_saline-Endothelial-Endothelial-Alv_Gen_Intermediate|Control_saline / Treatment groups by lineage, cell group, cell type

TIE1 CASP7 EGFLAM IFI16 EDIL3

1.69e-05200715041a34080120c9f613373c20dcc366292f558040
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TIE1 SMCHD1 EGFLAM IFI16 EDIL3

1.69e-0520071566f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

THSD4 MYLK SYNE1 NCAM1 BCHE

1.69e-05200715c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TIE1 SMCHD1 EGFLAM IFI16 EDIL3

1.69e-05200715b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

CACNA2D2 SYNE1 NCAM1 ABCB1 PYHIN1

1.69e-05200715f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

THSD4 CNNM2 MYLK SYNE1 PCDH11X

1.69e-052007158bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellileum-Absorptive_Enterocytes|ileum / shred on tissue and cell subclass

APOB ABCB1 FABP6

3.85e-0541713650cec538c6acd92f45d804b3c94248c6231aa21
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

THSD4 SYNE1 SMCHD1 APOB

4.21e-0512171419333a660800b583fa27b495c1f7828e6636a257
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))-|Thalamus / BrainAtlas - Mouse McCarroll V32

BNIPL APOB STRC

1.04e-0457713ef44602342511a9f90c93463628ad8b154cb26fb
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))|Thalamus / BrainAtlas - Mouse McCarroll V32

BNIPL APOB STRC

1.04e-0457713a3dc14f7a63cc70b2789770644e0b9453426c6f9
ToppCellLeuk-UTI-Lymphocyte-T_NK-MAIT|Leuk-UTI / Disease, Lineage and Cell Type

CNNM2 SYNE1 ABCB1 PYHIN1

1.05e-04153714ac3a1d1b5bf6009df818fd757dad7382d95c60dc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TIE1 PCDH11X LAMA3

1.07e-04154714e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellsevere_influenza-NK_CD56bright|severe_influenza / disease group, cell group and cell class (v2)

TIE1 NCAM1 ABCB1 PYHIN1

1.16e-04157714fabaf54429dd5a899f9192f0d42522109ca36b9b
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2|TCGA-Lung / Sample_Type by Project: Shred V9

ATP7B ACRV1 NCAM1 MSH2

1.18e-041587149dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL6 COL6A5 DNAH9 GPR179

1.21e-0415971400a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MYLK LAMA3 EGFLAM EDIL3

1.27e-0416171447b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 LAMA3 ABCB1 PYHIN1

1.27e-04161714bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCellHealthy-NK_CD56bright|Healthy / disease group, cell group and cell class

TIE1 NCAM1 ABCB1 FABP6

1.37e-04164714ed193211965accba60a256d3e6c159f0fc911d8b
ToppCelllung-Club_Cells|lung / shred on tissue and cell subclass

CLCA1 DSC2 CASP7 IFI16

1.37e-04164714b12cacd499b18b96120ca6d14646aebeaed41d10
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK LAMA3 EGFLAM EDIL3

1.40e-04165714f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA3 PABPC4L ABCB1

1.43e-041667148e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

ERICH3 ACRV1 DNAH9 FABP6

1.47e-04167714442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCellSevere-Lymphoid-NK-CD8_T|Severe / Condition, Lineage, Cell class and cell subclass

CACNA2D2 SYNE1 ABCB1 PYHIN1

1.47e-041677148d41015871616ab7eced5104cd8f70d0efe504f2
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 MYLK EGFLAM STRC

1.60e-04171714b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 MYLK EGFLAM STRC

1.60e-041717149d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN MYL6B NCAM1 DENND3

1.60e-04171714d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 NCAM1 ABCB1 PYHIN1

1.60e-04171714adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CACNA2D2 SYNE1 NCAM1 PYHIN1

1.60e-0417171404c811817cfec45af5f2891793106cc7ddb0300e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 NCAM1 ABCB1 PYHIN1

1.64e-0417271468fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|367C / Donor, Lineage, Cell class and subclass (all cells)

BNIPL NCAM1 ABCB1 PYHIN1

1.64e-041727146379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA2D2 SYNE1 NCAM1 PYHIN1

1.64e-0417271486f52f486d67217fc1b8443ab362c975df2974a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA2D2 SYNE1 NCAM1 PYHIN1

1.64e-04172714fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA2D2 SYNE1 NCAM1 PYHIN1

1.64e-04172714e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Fos_(Deep_layer_pyramidal_cells_(IEG))|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CLCA1 DSC1 APOB

1.68e-0467713b17d498034ab8280be4991cca1527373d7e43f38
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

5.71e-062712DOID:0110471 (implicated_via_orthology)
Diseasearrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)

DSC1 DSC2

5.68e-055712DOID:0050431 (implicated_via_orthology)
Diseasedesmocollin-2 measurement

DSC1 DSC2

5.68e-055712EFO_0021936
Diseasefamilial hyperlipidemia (is_implicated_in)

APOB ABCB1

1.58e-048712DOID:1168 (is_implicated_in)
Diseaseepilepsy (is_implicated_in)

BCHE ABCB1

2.03e-049712DOID:1826 (is_implicated_in)
DiseaseMalignant neoplasm of breast

FASN ATP7B SYNE1 POLH DDX18 EIF5 CASP7 BCHE DNAH9 ABCB1

2.41e-0410747110C0006142
Diseasecytochrome p450 3a4 measurement

BCHE APOB

3.10e-0411712EFO_0020303
Diseasethoracic aortic aneurysm (is_implicated_in)

THSD4 MYLK

3.10e-0411712DOID:14004 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_implicated_in)

CASP7 MSH2 MSH3 ABCB1

3.59e-04139714DOID:3908 (is_implicated_in)
DiseaseParkinson Disease, Secondary Vascular

BCHE ABCB1

3.71e-0412712C0751414
DiseaseAtherosclerotic Parkinsonism

BCHE ABCB1

3.71e-0412712C0751415
DiseaseSecondary Parkinson Disease

BCHE ABCB1

3.71e-0412712C0030569
Diseaseintegral membrane protein 2B measurement

BCHE APOB

3.71e-0412712EFO_0802634
DiseaseHypertriglyceridemia

BCHE APOB

5.87e-0415712C0020557
Diseasesodium-coupled monocarboxylate transporter 1 measurement

BCHE APOB

9.51e-0419712EFO_0802076
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

MSH2 MSH3

9.51e-0419712C2936783
DiseaseUterine leiomyoma

SYNE1 NCAM1 ARMC2

1.39e-0391713HP_0000131
Diseasesmoking behavior

GAPVD1 CNNM2 NRAP DDX18 NCAM1

1.40e-03341715EFO_0004318
DiseaseColorectal Carcinoma

ATP7B FCN1 SYNE1 PCDH11X APOB MSH2 ABCB1

1.49e-03702717C0009402
Diseasenephrotic syndrome (implicated_via_orthology)

GAPVD1 COQ8A

1.52e-0324712DOID:1184 (implicated_via_orthology)
DiseaseDyslipidemias

ATP7B APOB

1.52e-0324712C0242339
DiseaseDyslipoproteinemias

ATP7B APOB

1.52e-0324712C0598784
DiseaseMammary Carcinoma, Human

FASN ATP7B SYNE1 CASP7 BCHE ABCB1

1.66e-03525716C4704874
DiseaseMammary Neoplasms, Human

FASN ATP7B SYNE1 CASP7 BCHE ABCB1

1.66e-03525716C1257931
DiseaseMammary Neoplasms

FASN ATP7B SYNE1 CASP7 BCHE ABCB1

1.69e-03527716C1458155
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

MSH2 MSH3

1.79e-0326712C0009405
Diseasecoronary artery disease (is_implicated_in)

MYLK BCHE APOB

1.83e-03100713DOID:3393 (is_implicated_in)
DiseaseBreast Carcinoma

FASN ATP7B SYNE1 CASP7 BCHE ABCB1

1.88e-03538716C0678222
DiseaseHereditary non-polyposis colorectal cancer syndrome

MSH2 MSH3

1.93e-0327712C1112155
Diseaseacute myocardial infarction (biomarker_via_orthology)

DSC2 CASP7

2.07e-0328712DOID:9408 (biomarker_via_orthology)
DiseaseNeurotoxicity Syndromes

BCHE ABCB1

2.22e-0329712C0235032
DiseaseEncephalopathy, Toxic

BCHE ABCB1

2.22e-0329712C0149504
DiseaseToxic Encephalitis

BCHE ABCB1

2.22e-0329712C0154659
DiseaseHereditary Nonpolyposis Colorectal Cancer

MSH2 MSH3

2.22e-0329712C1333990
Diseasebipolar disorder (is_implicated_in)

SYNE1 NCAM1

2.22e-0329712DOID:3312 (is_implicated_in)
DiseaseMarijuana Abuse

NCAM1 ABCB1

2.38e-0330712C0024809

Protein segments in the cluster

PeptideGeneStartEntry
TQKNEGMGGGRVVAV

ERICH3

1326

Q5RHP9
GFKMKDDVVLGIGVN

EPC1

671

Q9H2F5
TKNGKVRGMNLTVFG

BCHE

36

P06276
VDKQKIVEGMAEGGF

EGFLAM

711

Q63HQ2
FKEAVQGMVAKGTTG

CACNA2D2

356

Q9NY47
QNKGKKVAMVGDGVN

ATP7B

1256

P35670
EEGNMLGNKFKGRSI

ARMC2

301

Q8NEN0
QGEKGMQGEKGTQSE

ALPK3

901

Q96L96
GNKGAKGDMVVSRVK

COL4A4

551

P53420
GMILGKGNVKTQGEV

DSPP

406

Q9NZW4
GDFMKRVQESGIVKD

DENND3

651

A2RUS2
IKNGGQETIEMVKGG

DSC2

776

Q02487
KIFEGGKLQFMVQGC

ACRV1

221

P26436
AEGTGKKQQEGRAMA

ATXN7L1

16

Q9ULK2
TFMKQIAGGGDVTAK

INTS3

166

Q68E01
KINEGIGDKIGMFFQ

ABCB1

181

P08183
VKKVQQKEGGSDLGM

MSH3

101

P20585
MNGKEISGKIIFVGR

PABPC4

251

Q13310
GGVVNVGADIKKTME

PTPRN

376

Q16849
KLGRVVVKEGQMGRF

MYLK

166

Q15746
KVAVPMRFNGKSGVE

LAMA3

2386

Q16787
GKLIGAKDVQGDSQM

NRAP

831

Q86VF7
KGSFGEMGEQTVKAV

GPR179

1511

Q6PRD1
GEKGSDRFRQKVQEM

GAPVD1

236

Q14C86
MGTIQEAGKKTDVGV

BNIPL

1

Q7Z465
MVKKGQVTGVETDKG

PDPR

216

Q8NCN5
VMKVKVEDGGFPQRS

PCDH11X

216

Q9BZA7
GGMSQEAVGNIKVTK

DDX18

71

Q9NVP1
EQKFQKVKGFGGAMT

GBA

111

P04062
KGMRGEKGDAGQSQS

FCN1

96

O00602
KVKGTNEDMVFRGNI

EDIL3

261

O43854
QMIGEVIRKGSKNDF

APOB

811

P04114
EGKGNGIKTVIVNMV

EIF5

26

P55010
VGKESNIQTMGGKTF

FABP6

66

P51161
VGVGKANQKELEGMA

COL6A5

951

A8TX70
KGIGGMDGTQQQIFK

FASTKD1

691

Q53R41
MQKLFEGGKGSVFQR

RAP1GDS1

306

P52306
VMEVEVDGQKFQGAG

ILF3

556

Q12906
IQDKTGSMAVVGKGE

PYHIN1

346

Q6K0P9
TAVEQIGMFLGKVQG

COQ8A

46

Q8NI60
RGTVNVKGKGQMKTY

ADCY9

1226

O60503
KNFDKVTGMGVRNGT

CASP7

76

P55210
IQDDRGKMDVVGTGQ

IFI16

336

Q16666
GGKGMRIVRSEQEFQ

MCCC1

211

Q96RQ3
GQGIKTQQSFEMVKG

DSC1

771

Q08554
KVEKGDFQGLVEIMG

DNAH9

1136

Q9NYC9
RKEGVFAKEVRTGGM

FASN

666

P49327
GVVGVKMSAVDGQRQ

MSH2

146

P43246
VNKGEKGIMVLAGDT

NHP2

71

Q9NX24
RVKVMQEEGQSKGFG

PABPC4L

321

P0CB38
EIGVKKFMITGGNLQ

TATDN1

41

Q6P1N9
KGGKTVQMGQELQGE

SMCHD1

1156

A6NHR9
EGEVKLNMAIGKGEQ

SYNE1

2676

Q8NF91
FQVIMGRKRGNVEKG

TCAF1

421

Q9Y4C2
KAKMREQERQASGGG

TAF1

646

P21675
QGQGKGAMGTQKEVI

RUFY4

296

Q6ZNE9
TAEETVQKEGMRKQG

POLH

156

Q9Y253
MTAVVKIEKGVGGNN

SP1

11

P08047
GVVDVKGQVRMEVQG

PEX14

301

O75381
FRVKDGVKNMGTTGA

STRC

1101

Q7RTU9
GQKQGGFVVDKNTKM

CLCA1

536

A8K7I4
MADVVVGKDKGGEQR

CHRAC1

1

Q9NRG0
QGKVEVEAGKEGMKF

CNNM2

691

Q9H8M5
KLEGQMGEDGNSIKV

NCAM1

616

P13591
GGAFENMKEKINAVR

SPATS2

26

Q86XZ4
RVFDKEGNGKVMGAE

MYL6B

151

P14649
GEGNFGQVIRAMIKK

TIE1

846

P35590
KKVEMQGESAGEQVR

TTLL6

501

Q8N841
QGESAGEQVRKKGMR

TTLL6

506

Q8N841
GMKGFKGQLSRQVAD

YIPF3

81

Q9GZM5
FRVKDGVKNMGTTGA

STRCP1

1101

A6NGW2
MVTEGRSQEEGEQKG

THSD4

551

Q6ZMP0
RFKQEGVLNSKVGMD

THOP1

626

P52888